A dye endoscope capable of laser treatment and its application

Abstract

The embodiment of the present invention provides a dye endoscope capable of laser treatment, comprising: an endoscope having a head end and a tail end, wherein an image sensor capable of cutoff filtering is provided; a light processing system, one end of which is connected to the tail end through a fiber bundle formed by at least two cores or two optical fibers; a light source, which includes an infrared laser transmitter, a therapeutic laser transmitter, and a full-spectrum light source with controllable bandpass filtering, connected to the other end of the light processing system through an optical fiber. By integrating ordinary white light, narrow-band light, therapeutic laser, and visible infrared laser into the entire endoscope system, narrow-band light dyeing and laser treatment can be achieved, solving the pain point that traditional laser treatment needs to occupy the biopsy channel and requires multiple people to operate. A laser cutoff filter is set in the image sensor channel to solve the pain point of image overexposure caused by laser highlight.

Description

Technical Field

[0001] The invention relates to the technical field of medical instruments, and in particular to a dye endoscope capable of laser treatment and application thereof. Background Art

[0002] In medical clinical practice, an endoscope can enter the human body through natural cavities or percutaneous puncture channels, directly observe lesions in relevant parts, make a diagnosis of the lesions under observation, or take a biopsy of the lesion for pathological diagnosis. It can also provide timely treatment for the lesions or implant artificial products with therapeutic effects.

[0003] In the use of traditional endoscopes, only lesions with obvious changes in shape or color can be found, but small, flat early cancers and dysplasia are difficult to diagnose, and often lead to missed diagnosis; and when various benign and malignant lesions are found, as well as airway stenosis caused by various reasons, or symptoms such as stones, interventional treatment of the lesions is often required, which is often difficult to do with traditional endoscopes. In addition, when using traditional endoscopes, the laser optical fiber needs to be inserted into the lesion through the endoscopic biopsy operation channel, extending at least 1 cm from the distal end of the endoscope, and positioned with visible red light, and the laser is aligned and irradiated at a distance of 4 to 10 mm from the ablation target. This method requires the use of a biopsy channel and requires multiple people to operate. If the operators do not cooperate well, its efficiency will be reduced. In addition, when the existing endoscope is used, its laser highlight may cause the image to be overexposed. Therefore, the present application proposes a laser-treatable dye endoscope and its application to at least partially solve the problems that may exist in the prior art. Summary of the invention

[0004] In view of the above problems, embodiments of the present invention are proposed to provide a laser-treatable chromoendoscope and its application that overcomes the above problems or at least partially solves the above problems.

[0005] In order to solve the above problems, the embodiment of the present invention discloses a dye endoscope capable of laser treatment, comprising:

[0006] An endoscope having a head end and a tail end, wherein an image sensor capable of performing cutoff filtering is provided;

[0007] an optical processing system, one end of which is connected to the tail end through an optical fiber bundle formed by at least two cores or two optical fibers;

[0008] The light source, which includes an infrared laser transmitter, a therapeutic laser transmitter, and a full-spectrum light source with controllable bandpass filtering, is connected to the other end of the light treatment system via an optical fiber.

[0009] Preferably, the endoscope is further provided with an operation channel, a laser channel and at least one light source channel;

[0010] A cut-off filter is provided at the front end of the image sensor;

[0011] A lens is arranged at the front end of the laser channel.

[0012] Preferably, the lens is a self-focusing lens.

[0013] Preferably, two light source channels are provided, and the light source channels are composed of multiple groups of optical fibers.

[0014] Preferably, the cutoff wavelength range of the cutoff filter is 400 to 2100 nm.

[0015] Preferably, a coupler and a beam splitter are provided at the other end of the light processing system;

[0016] The infrared laser emitter and the therapeutic laser emitter are respectively connected to the coupler via the optical fiber;

[0017] The full-spectrum light source is connected to the beam splitter through the optical fiber.

[0018] Preferably, the full-spectrum light source comprises at least one full-spectrum lamp and a bandpass filter.

[0019] Preferably, the full spectrum lamp includes a xenon lamp and a halogen lamp.

[0020] Preferably, the therapeutic laser emitter is a pulsed coherent laser.

[0021] The embodiment of the present invention further discloses a medical device, which uses the above-mentioned laser-treatable dye endoscope.

[0022] The embodiments of the present invention include the following advantages:

[0023] Through the endoscope, it has a head end and a tail end, which has an image sensor capable of cutoff filtering; a light processing system, one end of which is connected to the tail end through a fiber bundle formed by at least two cores or two optical fibers; a light source, which includes an infrared laser transmitter, a therapeutic laser transmitter, and a full-spectrum light source with controllable bandpass filtering, connected to the other end of the light processing system through an optical fiber. By combining ordinary white light, narrow-band light, therapeutic laser, and visible infrared laser in the entire endoscope system, narrow-band light staining and laser treatment can be achieved, solving the pain point that traditional laser treatment needs to occupy the biopsy channel and requires multiple people to operate. A laser cutoff filter is set in the image sensor channel to solve the pain point of image overexposure caused by laser highlight. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 It is a schematic structural diagram of a dye endoscope capable of laser treatment provided by one embodiment of the present invention;

[0025] Figure 2 It is a schematic diagram of the cross-sectional structure of an endoscope of a dye endoscope capable of laser treatment provided by one embodiment of the present invention;

[0026] Figure 3 It is a schematic diagram of light propagation of a self-focusing lens of a dye endoscope capable of laser treatment provided by one embodiment of the present invention.

[0027] The accompanying drawings are as follows:

[0028] 100, endoscope; 101, head end; 102, tail end; 103, image sensor; 104, cutoff filter; 105, light source channel; 106, operation channel; 107, laser channel; 108, lens; 200, light processing system; 201, fiber bundle; 202, optical fiber; 203, coupler; 204, beam splitter; 300, light source; 301, bandpass filter; 302, full-spectrum light source; 303, infrared laser emitter; 304, therapeutic laser emitter. DETAILED DESCRIPTION

[0029] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the present invention is further described in detail below with reference to the accompanying drawings and specific embodiments.

[0030] One of the core concepts of the embodiments of the present invention is to integrate ordinary white light, narrow-band light, therapeutic laser and visible infrared laser in the entire endoscope system, so as to realize narrow-band light staining and laser treatment, thereby solving the pain points that traditional laser treatment needs to occupy the biopsy channel and requires multiple people to operate. A laser cutoff filter is set in the image sensor channel to solve the pain point of image overexposure caused by laser highlight.

[0031] Reference Figure 1 , shows a laser-treatable dye endoscope of the present invention, which may specifically include: an endoscope 100, which has a head end 101 and a tail end 102, wherein an image sensor 103 capable of cutoff filtering is provided; a light processing system 200, one end of which is connected to the tail end 102 via a fiber bundle 201 formed by at least two cores or two optical fibers; a light source 300, which includes an infrared laser emitter 303, a therapeutic laser emitter 304, and a full-spectrum light source 302 with controllable bandpass filtering, and is connected to the other end of the light processing system 200 via the optical fiber 202.

[0032] In this embodiment, by using the above-mentioned image sensor 103 with cutoff filtering and the full-spectrum light source 302 with controllable bandpass filtering, the corresponding wavelength is selected for filtering according to the tissue that needs optical staining analysis, and the image information reflected by the tissue can be optically stained by irradiating narrow-band light, so that the basic image processing is optimized. This is extremely helpful for the screening of tumors and cancerous lesions, and solves the problem that in the use of traditional endoscopes, only lesions with obvious changes in morphology or color can be found, but it is difficult to diagnose small, flat early cancers and dysplasia, and even often leads to missed diagnosis. The infrared laser emitter 303 and the therapeutic laser emitter 304 have the advantages of deep penetration, shallow thermal damage depth, small thermal damage to surrounding tissues, not easy to damage deep tissues, good safety, and especially can ensure the advantages of accurate and safe local operation and few complications, etc., which solves the problem that it is difficult to implement interventional treatment of lesions through traditional endoscopes when various benign and malignant lesions are found, as well as airway stenosis or stones caused by various reasons.

[0033] In one embodiment of the present application, Figures 1 to 3 As shown, a dye endoscope capable of laser treatment comprises: an endoscope 100, which has a head end 101 and a tail end 102, wherein an image sensor 103 capable of cut-off filtering is provided therein; the endoscope 100 is also provided with an operation channel 106, a laser channel 107 and at least one light source channel 105; a cut-off filter 104 is provided at the front end of the image sensor 103; a lens 108 is provided at the front end of the laser channel 107; a light processing system 200, one end of which is connected to the tail end 102 through a fiber bundle 201 formed by at least two cores or two optical fibers; a light source 300, which comprises an infrared laser emitter 303, a therapeutic laser emitter 304 and a full-spectrum light source 302 with controllable bandpass filtering, and is connected to the other end of the light processing system 200 through the optical fiber 202.

[0034] By selecting a bandpass filter of the corresponding wavelength according to the tissue that needs optical staining analysis, optical staining can be performed by irradiating the tissue with narrow-band light and reflecting the image information, which solves the pain point that traditional laser treatment needs to occupy the biopsy channel and requires multiple people to operate. Through the above multiple channels, such as the separation of viewing and operation channels; through the image sensor that can perform cut-off filtering, the pain point of image overexposure caused by laser highlight is solved. By using an infrared laser transmitter and applying visible red light positioning, the accuracy of positioning is ensured. By setting a corresponding lens in front of the above laser channel, the laser beam can be focused to a specific position, such as Figure 3As shown, the above-mentioned lens can make the laser beam emit light smoothly and continuously converge to one point, so as to concentrate the energy. For example, the lens can focus the laser beam to a small point. In addition, the lens can correct the optical distortion and deviation of the laser beam to make it more uniform and accurate, which is very important for maintaining the quality and stability of the laser beam and is conducive to maintaining high power density.

[0035] By designing the endoscope system, laser, visible infrared light and light source are combined in the endoscope system, solving the following pain points of conventional laser treatment: (1) In conventional equipment, multiple people are required to assist in inserting the optical fiber through the endoscope biopsy hole for visible red light positioning and then laser irradiation; through the dye endoscope of the present application, infrared laser, therapeutic laser and full-spectrum light can be directly integrated. In addition, the full-spectrum light is used to output the full-spectrum light source through controllable bandpass filtering or through narrow-band light for daily diagnosis and treatment or narrow-band light staining lesion screening. (2) Through the endoscope system structure of the present application, the problem of occupying the biopsy operation channel of the endoscope when using a traditional endoscope is solved, and the repeated extraction and insertion are required when switching the operating instrument, which affects the treatment work efficiency. (3) The cost of disinfection of the optical fiber after surgery is reduced. (4) By using different light sources, the accuracy and safety of treatment are improved, and the incidence of complications is reduced. (5) Through reasonable structural design, the overall performance and service life of the endoscope system are improved.

[0036] In one embodiment of the present application, Figure 1 As shown, the other end of the light processing system 200 is provided with a coupler 203 and a beam splitter 204; the infrared laser emitter 303 and the therapeutic laser emitter 304 are respectively connected to the coupler 203 through the optical fiber 202; the full spectrum light source 302 is connected to the beam splitter 204 through the optical fiber 202. The laser of the laser emitter is coupled to the light processing system through the coupler 203 for fusion, and then transmitted to the laser channel 107 of the endoscope 100 through the optical fiber bundle, and then output through the head end 101 of the endoscope 100 through the channel; the light emitted by the full spectrum light source is evenly dispersed into multiple light source channels 105 through the beam splitter 204, and can also be transmitted to the endoscope 100 through the optical fiber 202 together with the therapeutic laser transmission channel.

[0037] In one embodiment of the present application, the full-spectrum light source 302 includes at least one full-spectrum lamp and a bandpass filter 301. For example, the full-spectrum lamp can be one or more combinations of xenon lamps and halogen lamps. A controllable bandpass filter 301 is arranged in front of these lamps, which can be controlled not to filter the output port, so that the light is transmitted to the light processing system 200 as full-spectrum light through the optical fiber 202, and then further processed. Different bandpass filters 301 can also be selected for filtering as needed. When narrow-band light is needed, the bandpass filter 301 is controlled to output narrow-band light that meets the needs.

[0038] As an example, in the laser-treatable dye endoscope of the present application, the following parts are included: a light source 300, a light processing system 200, and an endoscope 100; wherein the light source 300 includes a full-spectrum light source 302, a therapeutic laser emitter 304, and a visible infrared laser emitter 303 to form a light source system; a coupler 203, an optical fiber 202 (optical fiber), and a beam splitter 204 and other structures constitute the light processing system 200; the end of the endoscope head 101 and the optical fiber in the mirror body and other structures constitute the endoscope system; the light source in the light source system can be illuminated in two ways to achieve different purposes. One is to use a full-spectrum light source, such as a xenon lamp, a halogen lamp, etc., for daily diagnosis and treatment observation; the other is to use a bandpass filter for narrow-band filtering according to the wavelength required for narrow-band optical dyeing. For example, light with a wavelength of 415 nm is easily absorbed by the blood vessels on the surface of the mucosa, light with a wavelength of 540 nm is easily absorbed by the capillaries in the submucosal layer, light with a wavelength of 555 nm is easily absorbed by deoxyhemoglobin, light with a wavelength of 569 nm is easily absorbed by carboxyhemoglobin, and light with a wavelength of 577 nm is easily absorbed by oxyhemoglobin. According to the tissue to be optically stained and analyzed, a bandpass filter with a corresponding wavelength can be selected, and optical staining can be performed by irradiating the tissue with narrow-band light and reflecting the image information back.

[0039] The therapeutic laser emitter 304 in the light source system can preferably be a pulsed coherent laser, which can emit high-energy pulsed coherent laser to help treat diseases. The therapeutic lasers include holmium lasers, Nd:YAG lasers, CO2 lasers, and semiconductor lasers. The visible infrared laser emitter 303 can emit visible infrared lasers, which are continuous visible infrared lasers used for the emission and aiming of therapeutic lasers during surgery to avoid lesion positioning errors. The light sources output by the visible infrared laser emitter 303 and the therapeutic laser emitter 304 are input into the light processing system 200 and coupled to the same laser transmission channel through the coupler 203 to achieve laser fusion applications.

[0040] The full-spectrum light source 302 output by the light source system is transmitted to the light processing system 200 through the optical fiber 202 (optical fiber), evenly dispersed into two channels through the beam splitter, and transmitted to the endoscope 100 together with the treatment laser transmission channel through the optical fiber bundle 201. The light processing system 200 can switch between ordinary white light diagnosis and treatment mode, narrow-band light staining screening mode and laser treatment mode according to clinical needs so as to output different lights.

[0041] It should be noted that the optical fiber bundle 201 is composed of at least one optical fiber 202 , and may be of the same configuration as the optical fiber 202 , or may be composed of a plurality of different optical fibers 202 .

[0042] In one embodiment of the present application, the lens 108 is a self-focusing lens. Figure 3 As shown, the transmission of laser-infrared light source through the above-mentioned self-focusing lens. In the laser treatment mode, a continuous visible infrared laser can be output in the laser channel, and the operator can observe the direction of the infrared laser through the image sensor. The visible infrared laser is used for aiming and positioning of laser treatment. Specifically, a Grin Lens (self-focusing lens) is set at the outermost side of the laser-infrared light source transmission channel. The lens is an optical lens with a refractive index distribution that gradually changes along the radial direction, which can achieve smooth and continuous convergence of the emitted light to one point, playing the role of laser focusing. The light source channel 105 is preferably set to two in the present application, and the light source channel 105 is composed of multiple groups of optical fibers; the light output by the light source system is transmitted to the light processing system 200 through the optical fiber 202, wherein the light is evenly dispersed into the two channels through the beam splitter 204, and the full spectrum light or narrow band light can also be combined with the coupler 203 through the beam splitter 204, and transmitted to the endoscope 100 through the optical fiber together with the treatment laser. The light treatment system 200 can select and switch between ordinary white light diagnosis and treatment mode, narrow-band light staining screening mode and laser treatment mode according to clinical needs.

[0043] In order to adapt to more wavelengths, the above-mentioned cutoff filter 104 preferably has a cutoff wavelength range of 400 to 2100 nm. Specifically, light with a wavelength of 415 nm is easily absorbed by the mucosal surface blood vessels, light with a wavelength of 540 nm is easily absorbed by the capillaries in the submucosal layer, light with a wavelength of 555 nm is easily absorbed by deoxyhemoglobin, light with a wavelength of 569 nm is easily absorbed by carboxyhemoglobin, and 532 nm, 980 nm, 1064 nm, 2100 nm, etc., wherein, for example, 532 nm is in the green light band, and is mainly used for skin treatment and ophthalmic surgery, and has the advantages of having a shallower tissue penetration depth, a high absorption rate, and a stronger photothermal effect. This makes it advantageous in the treatment of vascular lesions (such as vasodilation, pigmentation and hemangioma) and laser keratoplasty; 980nm is a near-infrared light band, mainly used for laser surgery and laser thermal therapy, with advantages including high tissue transparency, low tissue absorption rate, large penetration depth and good photothermal conversion efficiency. Light of this wavelength has good applications in neurosurgery, tumor resection and local tissue regeneration, etc. 1064nm is also a near-infrared light band. In laser surgery and skin surface treatment, due to its relatively large transmission depth, good tissue penetration and low absorption rate, light of this wavelength has outstanding effects in smoothing fine lines on the skin, skin plastic surgery, acne treatment, tattoo removal, etc.; 2100nm is a mid-infrared light band, with a high absorption rate in the skin and tissue, and performs well in skin cutting, dermal tissue regeneration, fat dissolution and skin tightening. In addition, lasers with a wavelength of 2100nm can also be used to treat varicose veins and varicose veins.

[0044] Based on the same concept, in one embodiment of the present application, a medical device is also disclosed. The medical device uses the above-mentioned laser-treatable chromoendoscope, and can display the image acquired by the image sensor 103 in the above-mentioned chromoendoscope through a display, or store it as image data. For example, the lesion can be analyzed through the image data.

[0045] The beneficial effects of the present application also include that the light source can be switched between ordinary white light or dyed narrow-band light by switching the bandpass filter as needed, which provides great convenience and practicality for realizing optical dyeing. The laser channel is integrated in the endoscope. Compared with the traditional laser treatment, which requires a second person to insert the laser optical fiber into the lesion through the biopsy instrument channel, it not only avoids occupying the biopsy instrument channel, but also allows the operator to operate alone, improving the stability and uniformity of the operation. The continuous visible infrared laser and the therapeutic laser are coupled in the same optical transmission channel. The direction of the infrared laser can be observed by the image sensor, which can be used to assist the operator in aiming and positioning during laser treatment. A laser filter is set outside the image sensor channel to filter the light of the corresponding wavelength of the laser, avoiding the problem of image overexposure caused by laser highlight.

[0046] The various embodiments in this specification are described in a progressive manner, and each embodiment focuses on the differences from other embodiments. The same or similar parts between the various embodiments can be referenced to each other.

[0047] It will be appreciated by those skilled in the art that the embodiments of the present invention may be provided as methods, devices, or computer program products. Therefore, the embodiments of the present invention may take the form of a complete hardware embodiment, a complete software embodiment, or an embodiment combining software and hardware. Moreover, the embodiments of the present invention may take the form of a computer program product implemented on one or more computer-usable storage media (including but not limited to disk storage, CD-ROM, optical storage, etc.) containing computer-usable program codes.

[0048] The embodiments of the present invention are described with reference to the flowcharts and / or block diagrams of the methods, terminal devices (systems), and computer program products according to the embodiments of the present invention. It should be understood that each process and / or block in the flowchart and / or block diagram, as well as the combination of the processes and / or blocks in the flowchart and / or block diagram, can be implemented by computer program instructions. These computer program instructions can be provided to a processor of a general-purpose computer, a special-purpose computer, an embedded processor, or other programmable data processing terminal device to generate a machine, so that the instructions executed by the processor of the computer or other programmable data processing terminal device generate instructions for implementing the processes in the flowchart and / or block diagram. Figure 1 A process or multiple processes and / or boxes Figure 1 A device that provides the functions specified in a block or multiple blocks.

[0049] These computer program instructions may also be stored in a computer-readable memory capable of directing a computer or other programmable data processing terminal device to operate in a specific manner, so that the instructions stored in the computer-readable memory produce a manufactured product including an instruction device, which implements the process Figure 1 A process or multiple processes and / or boxes Figure 1 A function specified in one or more boxes.

[0050] These computer program instructions can also be loaded onto a computer or other programmable data processing terminal device so that a series of operating steps are executed on the computer or other programmable terminal device to produce a computer-implemented process, thereby providing instructions for executing on the computer or other programmable terminal device to implement the process. Figure 1 A process or multiple processes and / or boxes Figure 1 The steps for the functions specified in one or more boxes.

[0051] Although the preferred embodiments of the present invention have been described, those skilled in the art may make additional changes and modifications to these embodiments once they have learned the basic creative concept. Therefore, the appended claims are intended to be interpreted as including the preferred embodiments and all changes and modifications that fall within the scope of the embodiments of the present invention.

[0052] Finally, it should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or terminal device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or terminal device. In the absence of further restrictions, the elements defined by the sentence "comprise a ..." do not exclude the existence of other identical elements in the process, method, article or terminal device including the elements.

[0053] The above is a detailed introduction to a laser-therapy-capable dye endoscope and its application provided by the present invention. Specific examples are used in this article to illustrate the principles and implementation methods of the present invention. The description of the above embodiments is only used to help understand the method of the present invention and its core idea. At the same time, for those skilled in the art, according to the idea of ​​the present invention, there will be changes in the specific implementation method and application scope. In summary, the content of this specification should not be understood as a limitation on the present invention.

Claims

1. A laser-treatable dye endoscope, characterized in that: include: An endoscope having a head end and a tail end, wherein an image sensor capable of performing cutoff filtering is provided; an optical processing system, one end of which is connected to the tail end through an optical fiber bundle formed by at least two cores or two optical fibers; A light source, which includes an infrared laser transmitter, a therapeutic laser transmitter, and a full-spectrum light source with controllable bandpass filtering, connected to the other end of the light treatment system via an optical fiber; Select a bandpass filter of the corresponding wavelength according to the tissue that needs optical staining analysis, and optical staining can be performed by irradiating the tissue with narrow-band light and reflecting the image information; By using an infrared laser transmitter, visible red light positioning is applied; The light sources output by the visible infrared laser transmitter and the therapeutic laser transmitter are input into the light processing system and coupled into the same laser transmission channel through a coupler to realize laser fusion application.

2. The dye endoscope according to claim 1, characterized in that: The endoscope is also provided with an operation channel, a laser channel and at least one light source channel; A cut-off filter is provided at the front end of the image sensor; A lens is arranged at the front end of the laser channel.

3. The dye endoscope according to claim 2, characterized in that: The lens is a self-focusing lens.

4. The dye endoscope according to claim 2, characterized in that: There are two light source channels, and the light source channels are composed of multiple groups of optical fibers.

5. The dye endoscope according to claim 2, characterized in that: The cut-off wavelength range of the cut-off filter is 400 to 2100 nm.

6. The dye endoscope according to claim 1, characterized in that: The other end of the light processing system is provided with a coupler and a beam splitter; The infrared laser emitter and the therapeutic laser emitter are respectively connected to the coupler via the optical fiber; The full-spectrum light source is connected to the beam splitter through the optical fiber.

7. The chromoendoscope according to claim 1, characterized in that: The full-spectrum light source includes at least one full-spectrum lamp and a bandpass filter.

8. The dye endoscope according to claim 7, characterized in that: The full spectrum lamps include xenon lamps and halogen lamps.

9. The dye endoscope according to claim 7, characterized in that: The therapeutic laser emitter is a pulsed coherent laser.

10. A medical device, characterized in that: The medical device uses the laser-treatable chromoendoscope described in any one of claims 1 to 9 above.

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