A herbicidal composition containing dichloroisoniximone and mesosulfuron and its application

Abstract

The present application relates to the technical field of pesticides, in particular to a herbicidal composition containing dichloroisoxyfluorfen and mesosulfuron-methyl and application thereof, wherein the weight ratio of dichloroisoxyfluorfen to mesosulfuron-methyl in the composition is 1:0.004-1.5. The composition can significantly reduce the phytotoxicity of herbicides on crops and has a synergistic effect on weeds, and is an ideal herbicide.

Description

[0001] This application claims priority to the Chinese patent application No. 202311799218.3, filed on December 25, 2023, and entitled "Herbicidal composition containing dichloro-isoxyfluro and mesosulfuron and its application", the entire content of which is incorporated herein by reference. TECHNICAL FIELD

[0002] The present application relates to the technical field of pesticides, in particular, to a herbicidal composition containing dichloro-isoxyfluro and mesosulfuron and its application in controlling weeds in agricultural fields. BACKGROUND

[0003] Wheat is the third largest food crop in China after corn and rice, accounting for more than 20% of the total grain output in China. Therefore, ensuring the sustainable high yield of wheat is of great significance to maintaining China's grain self-sufficiency and ensuring national food security. However, wheat production is threatened by many factors, one of which is weeds. In China, the area of wheat fields infested by weeds accounts for more than 90% of the total planting area, and the yield loss is up to 15%. Meanwhile, with the continuous increase of labor costs in China, the use of herbicides to control weed damage in wheat fields has become a necessary measure for wheat production.

[0004] Dichloro-isoxyfluro is a new type of isoxazoline ketone herbicide, which can be absorbed by the roots and young shoots of weeds, transported to various parts of the plant through transpiration, inhibit 1-deoxy-D-xylulose 5-phosphate synthase, block the synthesis of carotenoids, cause the leaves of the plant to turn white, and eventually die due to the inability to perform photosynthesis. It can be used to control various grasses and broadleaf weeds in wheat, corn, cotton and other crop fields. In wheat fields, dichloro-isoxyfluro has good control effect on many weeds such as Galium aparine, Descurania sophia, Galium spurium, Galium aparine, Veronica longifolia, Alopecurus aequalis, Alopecurus pratensis, Alopecurus japonicus, and Lolium multiflorum. In particular, due to its novel mechanism of action, it also has good control effect on resistant weeds, and plays an important role in the control of resistant weeds in wheat fields. However, dichloro-isoxyfluro has poor safety to wheat and can cause phytotoxicity under low temperature conditions. Therefore, improving the safety of dichloro-isoxyfluro to wheat and reducing the risk of phytotoxicity are of great significance to the control of weeds in wheat fields. SUMMARY

[0005] The purpose of the present application is to provide a herbicidal composition and its formulation which can significantly reduce the phytotoxicity of dichloro-isoxyfluro to wheat, and which is used for controlling weeds in wheat fields and has less phytotoxicity to wheat than dichloro-isoxyfluro alone.

[0006] In one aspect, the present application relates to a herbicidal composition containing dichloro-isoxyfluro and mesosulfuron, wherein the weight ratio of dichloro-isoxyfluro to mesosulfuron is 1:0.004-1.5.

[0007] Preferably, the weight ratio of dichloroisonixaben and mesosulfuron-methyl is 1:0.008-0.2.

[0008] More preferably, the weight ratio of dichloroisonixaben and mesosulfuron-methyl is 1:0.02-0.15.

[0009] Another aspect of the present application relates to a herbicide containing the above-mentioned herbicidal composition of dichloroisonixaben and mesosulfuron-methyl.

[0010] In the herbicide described in the present application, dichloroisonixaben and mesosulfuron-methyl account for 5% to 90% of the total weight, preferably 20% to 60%, and further 25% to 50%.

[0011] The herbicide described in the present application can be added with an agriculturally acceptable adjuvant and / or carrier, and processed into any pesticide-acceptable dosage form as needed, such as wettable powder, suspension concentrate, water dispersible granule, suspoemulsion, microemulsion, aqueous emulsion, emulsifiable concentrate, oil miscible flowable concentrate, soluble powder, dry flowable concentrate, granule, powder, water agent, oil agent, and microcapsule flowable concentrate, among which the preferred dosage forms are wettable powder, suspension concentrate, and water dispersible granule.

[0012] The agriculturally acceptable adjuvant and / or carrier described in the present application includes but is not limited to dispersant, wetting agent, disintegrant, binder, release agent, solvent, emulsifier, co-emulsifier, stabilizer, antifoaming agent, tackifier, density regulator, pH regulator, antifreeze, preservative, penetrant, carrier, etc.

[0013] When the composition is made into wettable powder, it contains the following components and weight contents: dichloroisonixaben 20% to 45%, mesosulfuron-methyl 0.1% to 20%, carrier 20% to 50%, wetting agent 3% to 10%, dispersant 3% to 10%, antifoaming agent 0.1% to 3%, and the rest is filler.

[0014] The preparation method can be, for example, first adsorbing dichloroisonixaben technical material onto a carrier and drying, then mixing the carrier adsorbed with dichloroisonixaben technical material, mesosulfuron-methyl technical material, wetting agent, dispersant, antifoaming agent, and filler, mixing uniformly in a mixing cylinder, and then crushing with an air flow crusher and mixing uniformly again.

[0015] When the composition is made into suspension concentrate, it contains the following components and weight contents: dichloroisonixaben 15% to 45%, mesosulfuron-methyl 0.1% to 10%, carrier 15% to 50%, dispersant 3% to 10%, tackifier 0.1% to 0.5%, antifreeze 2% to 5%, antifoaming agent 0.1% to 5%, preservative 0.1% to 1%, and the rest is deionized water.

[0016] The preparation method can be, for example, as follows: first, adsorb the dichloroisonixappeton technical material onto the carrier and dry, then add the carrier adsorbed with the dichloroisonixappeton technical material, the mesosulfuron-methyl technical material, the dispersing agent, part of the water into a homogenizer for coarse crushing, add a sand mill for ultra-micro grinding and crushing, then add the rest of the water in which the tackifier, the antifreezing agent, the defoaming agent and the preservative are dissolved into the homogenizer, and mix well to obtain the product.

[0017] When the composition is made into a water dispersible granule, the composition comprises the following components and weight contents: dichloroisonixappeton 10% to 45%, mesosulfuron-methyl 0.1% to 30%, carrier 10% to 50%, wetting agent 1% to 10%, dispersing agent 5% to 20%, binding agent 0.1% to 2%, disintegrating agent 1% to 5%, separating agent 0.1% to 2%, defoaming agent 0.1% to 5%, and filler to make up the balance.

[0018] The preparation method can be, for example, as follows: first, adsorb the dichloroisonixappeton technical material onto the carrier and dry, then add the carrier adsorbed with the dichloroisonixappeton technical material, the mesosulfuron-methyl technical material, the wetting agent, the dispersing agent, the binding agent, the disintegrating agent, the separating agent and the filler into water for grinding, then add the defoaming agent under the action of the homogenizer to obtain a slurry. The slurry is sent into a drying tower for spray drying, and the product is obtained after screening.

[0019] The dispersing agent can be one or more of sodium lignosulfonate, potassium lignosulfonate, ammonium lignosulfonate, NNO (sodium naphthalene sulfonate formaldehyde condensate), NO (sodium dibutyl naphthalene sulfonate formaldehyde condensate), diffusion agent MF (sodium methyl naphthalene sulfonate formaldehyde condensate), fatty alcohol ethylene oxide adduct phosphate, alkyl phenol polyoxyethylene ether phosphate, SOPA (alkyl phenol polyoxyethylene ether formaldehyde condensate sulfate), polyoxyethylene polyoxypropylene ether block copolymer, alkyl phenol polyoxyethylene phosphate, fatty amine polyoxyethylene ether, and hydrogenated castor oil EO adduct.

[0020] The wetting agent can be one or more of sodium dodecyl benzene sulfonate, sodium lauryl sulfate, dioctyl butanedioate sulfonate sodium, diisopropyl naphthalene sulfonate sodium, nonylphenol polyoxyethylene ether (NP), octylphenol polyoxyethylene ether, tridecyl alcohol polyoxyethylene ether, sodium dodecyl sulfate, fatty alcohol ethoxylate, alkyl phenol ethoxylate, naphthalene sulfonate, and sodium octadecyl butanedioate.

[0021] The defoaming agent can be one or more of isooctanol, isopentanol, stearic acid, lauric acid, ethylene oxide-propylene oxide block copolymer, and non-ionic soap defoaming agent.

[0022] The tackifier can be one or more of xanthan gum, gelatin, gum arabic, magnesium aluminum silicate, diatomite, bentonite, polyacrylate, natural polysaccharide, xanthan gum, gypsum, clay, water glass, sodium carboxymethyl starch, soluble starch, sodium carboxymethyl cellulose, hydroxyethyl cellulose, sodium alginate, agar;

[0023] The antifreezing agent can be one or more of ethylene glycol, propylene glycol, glycerol, polyethylene glycol, sorbitol, glycerol-ethyl ether diethylene glycol, methyl propylene glycol diethylene glycol;

[0024] The preservative can be one or more of formaldehyde, sodium salicylate, sodium benzoate, 1,2-benzothiazoline-3-ketone, 2-hydroxydiphenyl, sorbic acid, benzoic acid, benzaldehyde, p-hydroxybenzaldehyde, p-hydroxybenzyl;

[0025] The disintegrant can be one or more of thiamine, calcium chloride, aluminum chloride;

[0026] The binder can be one or more of polyvinyl acetate polymer, polyvinyl alcohol, ethylene-vinyl acetate copolymer, soluble starch;

[0027] The separating agent can be one or more of amorphous silica gel, aerosol silica gel;

[0028] The carrier and / or filler can be one or more of white carbon black, bentonite, kaolin, activated white clay, attapulgite, diatomite, light calcium carbonate, talc, leaf wax, clay;

[0029] The third aspect of the present application relates to the use of the above-mentioned herbicidal composition and / or herbicide in the control of agricultural weeds.

[0030] Preferably, the herbicidal composition and / or herbicide is used in the control of weeds in wheat field, such as tall oat grass, look grass, Japanese look grass, blackgrass, false oat, brome, broadcast weed, shepherd's purse, wheat public, cornflower, etc.

[0031] More preferably, the herbicidal composition and / or herbicide is used in the control of tall oat grass, look grass, shepherd's purse in wheat field.

[0032] Further, the herbicidal composition or herbicide of the present application reduces the phytotoxicity to crops when used in the control of agricultural weeds. Tests show that the phytotoxicity of dichloro-isoxadione to wheat is significantly lighter than that of dichloro-isoxadione alone when dichloro-isoxadione is mixed with herbicide methyldithiopyr.

[0033] In the application described in the present application, the effective component of the herbicidal composition and / or herbicide is used in the field at an amount of 10-500 g / hm 2 , preferably 150-250 g / hm 2 .

[0034] The herbicidal composition or the use method of the herbicide according to the present application includes, but is not limited to, being prepared into a mixed preparation, being used in a tank mix, or being used by adding other effective components or adjuvants.

[0035] The present application has the following positive beneficial effects:

[0036] 1. After the compounding of dichloroisonixiconone and mesosulfuron-methyl, the phytotoxicity to crops is obviously lighter than that of dichloroisonixiconone alone;

[0037] 2. After the compounding of dichloroisonixiconone and mesosulfuron-methyl, the obvious synergistic effect is obtained, and good control effect is obtained on resistant weeds;

[0038] 3. The action mechanisms of dichloroisonixiconone and mesosulfuron-methyl are different, and the compounding use can delay the weed resistance. BRIEF DESCRIPTION OF DRAWINGS

[0039] Figure 1 The phytotoxicity of dichloroisonixiconone to wheat;

[0040] Figure 2 The phytotoxicity of the herbicidal composition of the present application to wheat. DETAILED DESCRIPTION

[0041] The following examples are used to illustrate the present application, but are not used to limit the scope of the present application. If the specific technology or condition is not indicated in the examples, the technology or condition described in the literature in the art or according to the product instruction is used. Unless otherwise specified, the percentage in all examples of the present application refers to the weight percentage.

[0042] (I) Preparation Examples

[0043] Preparation Example 1: 30% dichloroisonixiconone·mesosulfuron-methyl wettable powder

[0044] Dichloroisonixiconone 29.9%, mesosulfuron-methyl 0.1%, white carbon black 35%, sodium dodecyl benzene sulfonate 3%, potassium lignosulfonate 3%, ethylene oxide-propylene oxide block copolymer 0.1%, diatomite to make up the balance.

[0045] First, the dichloroisonixiconone technical material is uniformly adsorbed on the white carbon black and dried, then the white carbon black adsorbed with the dichloroisonixiconone technical material, the mesosulfuron-methyl technical material, the sodium dodecyl benzene sulfonate, the potassium lignosulfonate, the ethylene oxide-propylene oxide block copolymer, and the diatomite are mixed, uniformly mixed in a mixing cylinder, and then uniformly mixed after being crushed by an air flow crusher.

[0046] Preparation Example 2: 20% dichloroisonixiconone·mesosulfuron-methyl suspension concentrate

[0047] Diclofop-P 19.8%, mesosulfuron-methyl 0.2%, white carbon black 25%, naphthalene sulfonate sodium formaldehyde condensate 3%, polyoxyethylene polyoxypropylene ether block copolymer 2%, magnesium aluminum silicate 0.2%, ethylene glycol 2%, isoamyl alcohol 1%, sodium benzoate 0.5%, and deionized water to make up the balance.

[0048] First, the diclofop-P technical material is uniformly adsorbed onto the white carbon black and dried, then the white carbon black adsorbed with the diclofop-P technical material, the mesosulfuron-methyl technical material, the naphthalene sulfonate sodium formaldehyde condensate, the polyoxyethylene polyoxypropylene ether block copolymer, and part of the water are coarsely mixed by a homogenizer, then added to a sand mill for ultra-micro grinding and crushing, and then the remaining water in which the magnesium aluminum silicate, the ethylene glycol, the isoamyl alcohol, and the sodium benzoate are dissolved is added under the action of the homogenizer, and thoroughly mixed to obtain the product.

[0049] Preparation Example 3: 30% diclofop-P·mesosulfuron-methyl water dispersible granules

[0050] Diclofop-P 29.7%, mesosulfuron-methyl 0.3%, white carbon black 35%, sodium dodecyl sulfate 2%, naphthalene sulfonate sodium formaldehyde condensate 5%, polyoxyethylene polyoxypropylene ether block copolymer 5%, polyvinyl acetate polymer 1%, thiamine 1%, amorphous silica gel 0.2%, isooctanol 0.2%, and kaolin to make up the balance.

[0051] First, the diclofop-P technical material is uniformly adsorbed onto the white carbon black and dried, then the white carbon black adsorbed with the diclofop-P technical material, the mesosulfuron-methyl technical material, the sodium dodecyl sulfate, the naphthalene sulfonate sodium formaldehyde condensate, the polyoxyethylene polyoxypropylene ether block copolymer, the polyvinyl acetate polymer, the thiamine, the amorphous silica gel, and the kaolin are ground in water, then the isoamyl alcohol is added under the action of the homogenizer to obtain a slurry. The slurry is sprayed and dried in a drying tower, and then sieved to obtain the product.

[0052] Preparation Example 4: 35% diclofop-P·mesosulfuron-methyl wettable powder

[0053] Diclofop-P 34.3%, mesosulfuron-methyl 0.7%, white carbon black 40%, dioctyl butanedioate sulfonate sodium 4%, potassium lignosulfonate 5%, isoamyl alcohol 0.3%, and diatomite to make up the balance.

[0054] First, the diclofop-P technical material is uniformly adsorbed onto the white carbon black and dried, then the white carbon black adsorbed with the diclofop-P technical material, the mesosulfuron-methyl technical material, the dioctyl butanedioate sulfonate sodium, the potassium lignosulfonate, the isoamyl alcohol, and the diatomite are mixed and uniformly mixed in a mixing cylinder, and then uniformly mixed after being crushed by an air flow crusher.

[0055] Preparation Example 5: 25% diclofop-P·mesosulfuron-methyl suspension concentrate

[0056] Dichloroisonixin 24.3%, mesosulfuron-methyl 0.7%, white carbon black 30%, alkylphenol polyoxyethylene ether phosphate 3%, alkylphenol polyoxyethylene phosphate 3%, magnesium aluminum silicate 0.2%, ethylene glycol 2%, stearic acid 1%, sodium salicylate 0.5%, deionized water to make up the balance.

[0057] First, the dichloroisonixin technical material is uniformly adsorbed onto the white carbon black and dried, then the white carbon black adsorbed with the dichloroisonixin technical material, the mesosulfuron-methyl technical material, the alkylphenol polyoxyethylene ether phosphate, the alkylphenol polyoxyethylene phosphate, and part of the water are coarsely mixed by a homogenizer, then added into a sand mill for ultra-micro grinding and crushing, and then the remaining water in which the magnesium aluminum silicate, the ethylene glycol, the stearic acid, and the sodium salicylate are dissolved is added under the action of the homogenizer, and thoroughly mixed to obtain the product.

[0058] Preparation Example 6: 35% dichloroisonixin·mesosulfuron-methyl water dispersible granules

[0059] Dichloroisonixin 32.6%, mesosulfuron-methyl 2.4%, white carbon black 35%, fatty alcohol ethoxylate 3%, sodium dibutylnaphthalene sulfonate formaldehyde condensate 6%, alkylphenol polyoxyethylene phosphate 6%, polyvinyl alcohol 1%, calcium chloride 1%, aerosol silica 0.2%, stearic acid 0.2%, activated white clay to make up the balance.

[0060] First, the dichloroisonixin technical material is uniformly adsorbed onto the white carbon black and dried, then the white carbon black adsorbed with the dichloroisonixin technical material, the mesosulfuron-methyl technical material, the fatty alcohol ethoxylate, the sodium dibutylnaphthalene sulfonate formaldehyde condensate, the alkylphenol polyoxyethylene phosphate, the polyvinyl alcohol, the calcium chloride, the aerosol silica, and the activated white clay are added into water for grinding, and then the stearic acid is added under the action of the homogenizer to obtain a slurry. The slurry is sent into a spray drying tower for spray drying, and then sieved to obtain the product.

[0061] Preparation Example 7: 40% dichloroisonixin·mesosulfuron-methyl wettable powder

[0062] Dichloroisonixin 36.9%, mesosulfuron-methyl 3.1%, white carbon black 40%, tridecyl alcohol polyoxyethylene ether 4%, sodium methyl naphthalene sulfonate formaldehyde condensate 2%, polyoxyethylene polyoxypropylene ether block copolymer 2%, ethylene oxide-propylene oxide block copolymer 0.5%, diatomite to make up the balance.

[0063] First, the dichloroisonixin technical material is uniformly adsorbed onto the white carbon black and dried, then the white carbon black adsorbed with the dichloroisonixin technical material, the mesosulfuron-methyl technical material, the tridecyl alcohol polyoxyethylene ether, the sodium methyl naphthalene sulfonate formaldehyde condensate, the polyoxyethylene polyoxypropylene ether block copolymer, the ethylene oxide-propylene oxide block copolymer, and the diatomite are mixed and uniformly mixed in a mixing cylinder, and then crushed by an air flow crusher.

[0064] Preparation Example 8: 30% klorvar·mesosulfuron suspension concentrate

[0065] klorvar 27.7%, mesosulfuron 2.3%, white carbon black 30%, sodium dibutylnaphthalene sulfonate formaldehyde condensate 4%, alkylphenol polyoxyethylene phosphoric ester 4%, polyacrylate 0.3%, glycerin 2%, lauric acid 1.5%, sorbic acid 1%, deionized water to make up the balance.

[0066] First, the klorvar TC was uniformly adsorbed onto the white carbon black and dried, then the white carbon black adsorbed with the klorvar TC, the mesosulfuron TC, the sodium dibutylnaphthalene sulfonate formaldehyde condensate, the alkylphenol polyoxyethylene phosphoric ester, and part of the water were coarsely mixed by a homogenizer, then the mixture was ultra-micro ground by a sand mill, and then the remaining water in which the polyacrylate, the glycerin, the lauric acid, and the sorbic acid were dissolved was added under the action of the homogenizer, and the mixture was thoroughly mixed to obtain the product.

[0067] Preparation Example 9: 40% klorvar·mesosulfuron water dispersible granule

[0068] klorvar 36.2%, mesosulfuron 3.8%, white carbon black 40.6%, alkylphenol ethoxylate 4%, sodium methylnaphthalene sulfonate formaldehyde condensate 6%, nonylphenol polyoxyethylene ether 6%, ethylene-vinyl acetate copolymer 2%, aluminum chloride 1%, amorphous silica gel 0.2%, lauric acid 0.2%.

[0069] First, the klorvar TC was uniformly adsorbed onto the white carbon black and dried, then the white carbon black adsorbed with the klorvar TC, the mesosulfuron TC, the alkylphenol ethoxylate, the sodium methylnaphthalene sulfonate formaldehyde condensate, the nonylphenol polyoxyethylene ether, the ethylene-vinyl acetate copolymer, the aluminum chloride, and the amorphous silica gel were ground in water, and then the lauric acid was added under the action of the homogenizer to obtain a slurry. The slurry was sprayed and dried in a drying tower, and the product was obtained after screening.

[0070] Preparation Example 10: 45% klorvar·mesosulfuron wettable powder

[0071] klorvar 39.5%, mesosulfuron 5.5%, white carbon black 43%, nonylphenol polyoxyethylene ether 5%, sodium methylnaphthalene sulfonate formaldehyde condensate 3%, polyoxyethylene-polyoxypropylene ether block copolymer 3%, isooctanol 1%.

[0072] First, the klorvar TC was uniformly adsorbed onto the white carbon black and dried, then the white carbon black adsorbed with the klorvar TC, the mesosulfuron TC, the nonylphenol polyoxyethylene ether, the sodium methylnaphthalene sulfonate formaldehyde condensate, the polyoxyethylene-polyoxypropylene ether block copolymer, and the isooctanol were mixed and uniformly mixed in a mixing cylinder, and then the mixture was uniformly mixed after being ground by an air flow crusher.

[0073] Formulation Example 11: 35% klorvar·mesosulfuron suspension concentrate

[0074] Klorvar 30.5%, mesosulfuron 4.5%, white carbon black 35%, alkylphenol polyoxyethylene ether phosphate 5%, polyoxyethylene polyoxypropylene ether block copolymer 5%, polyacrylate 0.5%, sorbitol 2%, stearic acid 1%, sodium salicylate 1%, deionized water to make up the balance.

[0075] First, the klorvar TC was uniformly adsorbed onto the white carbon black and dried, then the white carbon black adsorbed with klorvar TC, mesosulfuron TC, alkylphenol polyoxyethylene ether phosphate, polyoxyethylene polyoxypropylene ether block copolymer, part of the water were coarsely mixed by a homogenizer, then added into a sand mill for ultrafine grinding and crushing, and then the remaining water in which polyacrylate, sorbitol, stearic acid, and sodium salicylate were dissolved was added under the action of the homogenizer, and fully mixed to obtain the product.

[0076] Formulation Example 12: 25% klorvar·mesosulfuron water dispersible granules

[0077] Klorvar 20.9%, mesosulfuron 4.1%, white carbon black 25%, naphthalene sulfonate 2%, fatty alcohol ethylene oxide adduct phosphate 5%, fatty amine polyoxyethylene ether 5%, soluble starch 2%, thiamine 1%, aerosol silica 0.2%, isoamyl alcohol 0.3%, light calcium carbonate to make up the balance.

[0078] First, the klorvar TC was uniformly adsorbed onto the white carbon black and dried, then the white carbon black adsorbed with klorvar TC, mesosulfuron TC, naphthalene sulfonate, fatty alcohol ethylene oxide adduct phosphate, fatty amine polyoxyethylene ether, soluble starch, thiamine, aerosol silica, light calcium carbonate were ground in water, and then isoamyl alcohol was added under the action of the homogenizer to obtain a slurry. The slurry was sprayed and dried in a drying tower, and the product was obtained after sieving.

[0079] Formulation Example 13: 50% klorvar·mesosulfuron wettable powder

[0080] Klorvar 30.8%, mesosulfuron 19.2%, white carbon black 35%, diisopropyl naphthalene sulfonate sodium 7%, naphthalene sulfonate sodium formaldehyde condensate 3%, polyoxyethylene polyoxypropylene ether block copolymer 4%, lauric acid 1%.

[0081] First, the klorvar TC was uniformly adsorbed onto the white carbon black and dried, then the white carbon black adsorbed with klorvar TC, mesosulfuron TC, diisopropyl naphthalene sulfonate sodium, naphthalene sulfonate sodium formaldehyde condensate, polyoxyethylene polyoxypropylene ether block copolymer, lauric acid were mixed and uniformly mixed in a mixing cylinder, and then crushed by an air flow crusher and uniformly mixed again.

[0082] Formulation Example 14: 45% ipfencarbazone-methyl · mesosulfuron water dispersible granule

[0083] Ipfencarbazone 18.3%, mesosulfuron 26.7%, white carbon black 20%, sodium octadecyl succinate 5%, alkylphenol polyoxyethylene ether formaldehyde condensate sulfate 7%, hydrogenated castor oil EO adduct 7%, polyvinyl acetate polymer 2%, calcium chloride 1%, amorphous silica gel 0.3%, oxirane-oxpropylene block copolymer 0.4%, bentonite to make up the balance.

[0084] First, the ipfencarbazone TC is uniformly adsorbed on the white carbon black and dried, then the white carbon black adsorbed with ipfencarbazone TC, mesosulfuron TC, sodium octadecyl succinate, alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, hydrogenated castor oil EO adduct, polyvinyl acetate polymer, calcium chloride, amorphous silica gel, bentonite are added into water and ground, and then the oxirane-oxpropylene block copolymer is added under the action of the homogenizer to obtain a slurry. The slurry is sent into a spray drying tower for spray drying, and the product is prepared after sieving.

[0085] (B) Indoor bioassay examples

[0086] The indoor bioassay examples of the present application are carried out according to "Guidelines for Pesticide Indoor Bioassay Test Herbicide Part 7: Determination of Combined Action of Mixtures (NY / T 1155.7-2006)", and the combined action of two agents on crops and weeds after being mixed in a certain proportion is determined through indoor bioassay. The test method is as follows:

[0087] Accurately weigh 5.21 g of 96% ipfencarbazone TC, dissolve in 100 mL of petroleum ether to prepare a 50 g / L ipfencarbazone stock solution. Accurately weigh 5.26 g of 95% mesosulfuron TC, dissolve in 25 mL of N,N-dimethylformamide to prepare a 200 g / L mesosulfuron stock solution. During the test, appropriate amounts of ipfencarbazone stock solution and mesosulfuron stock solution are diluted with appropriate amounts of 0.1% Tween 80 aqueous solution to prepare the test solutions.

[0088] Pot culture test method is used, and the test targets are wheat and main weeds in wheat field, Alopecurus myosuroides, Bromus japonicus, and Capsella bursa-pastoris. In the sunlight greenhouse, plastic pots with a diameter of 12 cm and a height of 11 cm are used for seedling culture, and the seedlings are fixed before spraying, with 10 uniform wheat or weed plants in each pot. Stem and leaf spraying treatment is carried out at the 3-4 leaf stage, with 8 replicates for each treatment, and the amount of liquid is 450 L / hm 2 . After 14 days, the fresh weight of the aboveground part of each pot is weighed, and the actual phytotoxicity rate / efficacy E of each treatment is calculated:

[0089]

[0090] PT - fresh weight of the treatment group;

[0091] CK - fresh weight of the blank control group.

[0092] The joint action of the two herbicides in a certain ratio on wheat or weeds was evaluated by Gowing method. The theoretical phytotoxicity rate / efficacy E0of the mixture was calculated according to the formula:

[0093]

[0094] X - phytotoxicity rate / efficacy when the amount of herbicide A is P;

[0095] Y - phytotoxicity rate / efficacy when the amount of herbicide B is Q;

[0096] E0 - theoretical phytotoxicity rate / efficacy of the mixture when the amount of herbicide A is P and the amount of herbicide B is Q;

[0097] E - actual phytotoxicity rate / efficacy of the mixture when the amount of herbicide A is P and the amount of herbicide B is Q.

[0098] E - E0> 10% is synergistic effect; E - E0< -10% is antagonistic effect; -10% < E - E0< 10% is additive effect.

[0099] Example 1 of indoor bioassay:

[0100] The test target was wheat (variety Jimei 22), and the amount of each treatment and the control effect are shown in Table 1. The bioassay results showed that when the ratio of dichloroisonicotinic acid ketone and mesosulfuron-methyl was in the range of 1:0.004-1.5, the value of E-E0was -20.1% to -11.4%, indicating that the mixture of the two in the range of 1:0.004-1.5 had obvious antagonistic effect on the phytotoxicity rate of wheat, which could significantly reduce the phytotoxicity to wheat. When the ratio of dichloroisonicotinic acid ketone and mesosulfuron-methyl was in the range of 1:0.008-0.2, the value of E-E0was -20.1% to -12.2%, indicating that the mixture of the two in the range of 1:0.008-0.2 had more obvious antagonistic effect on the phytotoxicity rate of wheat. When the ratio of dichloroisonicotinic acid ketone and mesosulfuron-methyl was in the range of 1:0.02-0.15, the value of E-E0was -20.1% to -17.9%, indicating that the mixture of the two in the range of 1:0.02-0.15 had the most obvious antagonistic effect on the phytotoxicity rate of wheat.

[0101] Table 1 Bioassay results of dichloroisonicotinic acid ketone and mesosulfuron-methyl in different ratios on wheat

[0102]

[0103]

[0104] Indoor bioassay example 2:

[0105] The test target was Alopecurus pratensis, and the dosage and control effect of each treatment agent are shown in Table 2. The bioassay results showed that dichloroisoniximone and mesosulfuron-methyl in the range of 1:0.004-1.5, the E-E0 value was 10.9%-21.7%, indicating that the two in the range of 1:0.004-1.5 mixed, Alopecurus pratensis had obvious synergistic effect. Dichloroisoniximone and mesosulfuron-methyl in the range of 1:0.008-0.2, the E-E0 value was 13.1%-21.7%, indicating that the two in the range of 1:0.008-0.2 mixed, Alopecurus pratensis had more obvious synergistic effect. Dichloroisoniximone and mesosulfuron-methyl in the range of 1:0.02-0.15, the E-E0 value was 15.0%-21.7%, indicating that the two in the range of 1:0.02-0.15 mixed, Alopecurus pratensis had the most obvious synergistic effect.

[0106] Table 2 Bioassay results of dichloroisoniximone and mesosulfuron-methyl in different proportions on Alopecurus pratensis

[0107]

[0108]

[0109] Indoor bioassay example 3:

[0110] The test target was Alopecurus pratensis, and the dosage and control effect of each treatment agent are shown in Table 2. The bioassay results showed that dichloroisoniximone and mesosulfuron-methyl in the range of 1:0.004-1.5, the E-E0 value was 10.9%-21.7%, indicating that the two in the range of 1:0.004-1.5 mixed, Alopecurus pratensis had obvious synergistic effect. Dichloroisoniximone and mesosulfuron-methyl in the range of 1:0.008-0.2, the E-E0 value was 13.1%-21.7%, indicating that the two in the range of 1:0.008-0.2 mixed, Alopecurus pratensis had more obvious synergistic effect. Dichloroisoniximone and mesosulfuron-methyl in the range of 1:0.02-0.15, the E-E0 value was 15.0%-21.7%, indicating that the two in the range of 1:0.02-0.15 mixed, Alopecurus pratensis had the most obvious synergistic effect.

[0111] Table 3 Bioassay results of dichloroisoniximone and mesosulfuron-methyl in different proportions on Alopecurus pratensis

[0112]

[0113]

[0114] Indoor bioassay example 4:

[0115] The target plant was shepherd's purse. The dosage and efficacy of each treatment are shown in Table 4. Biochemical tests showed that when the ratio of dichlorvos to mesosulfuron-methyl was between 1:0.004 and 1.5, the E-E0 value ranged from 12.1% to 27.1%, indicating that the mixture of the two in this range had a significant synergistic effect on shepherd's purse. When the ratio of dichlorvos to mesosulfuron-methyl was between 1:0.008 and 0.2, the E-E0 value ranged from 18.5% to 27.1%, indicating that the mixture of the two in this range had an even more significant synergistic effect on shepherd's purse. When the ratio of dichlorvos to mesosulfuron is in the range of 1:0.02-0.15, the E-E0 value is 24.2% to 27.1%, indicating that the combination of the two in the range of 1:0.02-0.15 has the most significant synergistic effect on shepherd's purse.

[0116] Table 4. Results of bioassays on shepherd's purse with different ratios of dichloroisoxamate and mesosulfuron-methyl.

[0117]

[0118] (III) Examples of Field Efficacy Trials

[0119] The field efficacy test examples of this invention were conducted in accordance with the "Guidelines for Field Efficacy Tests of Pesticides (I) Herbicides for the Control of Weeds in Wheat Crops (GB / T17980.41-2000)". Field plot trials were conducted to verify the results of the indoor bioassay tests and to clarify the effect of the two agents, when combined in a certain proportion, on reducing phytotoxicity to wheat and their field control effect on weeds. The test methods are as follows:

[0120] Foliar spraying at the 3-5 leaf stage after winter wheat sowing (mid-November), with a solution volume of 450 L / hm². 2 Each treatment was repeated four times, with a plot size of 125 m², arranged in a randomized block design. A survey was conducted 15 days post-treatment. Four sampling points were randomly selected from each plot to investigate the aboveground fresh weight of all wheat seedlings or all weeds within each sampling point. Each wheat sampling point was 0.25 m². 2 Each weed sampling point is 1m in size. 2 Calculate the actual phytotoxicity rate / control efficacy E for each treatment:

[0121]

[0122] In the formula: PT—fresh weight of wheat / weeds in the treated area;

[0123] CK – Fresh weight of wheat / weeds in the blank control area.

[0124] The data obtained in the investigation, with reference to the Pesticide Indoor Biological Test Guideline Herbicide Part 7: Mixed Combined Action Determination (NY / T 1155.7-2006), the combined action of two pesticides in a certain proportion on wheat or weeds is evaluated by Gowing method, and the theoretical phytotoxicity / efficacy E0 of the mixture is calculated by the following formula:

[0125]

[0126] In the formula, X is the phytotoxicity / efficacy when the amount of herbicide A is P;

[0127] Y is the phytotoxicity / efficacy when the amount of herbicide B is Q;

[0128] E0 is the theoretical phytotoxicity / efficacy when the amount of herbicide A is P and the amount of herbicide B is Q;

[0129] E is the actual phytotoxicity / efficacy when the amount of herbicide A is P and the amount of herbicide B is Q.

[0130] E-E0>10% is synergistic effect; E-E0<-10% is antagonistic effect; -10%<E-E0<10% is additive effect.

[0131] The test is carried out in Wagu Village, Nanhew District, Xingtai City, Hebei Province, the wheat variety is Tianci Mai No. 1, and the main weeds in the field are Alopecurus carinatus and Brassica campestris, and the weeds are uniformly distributed.

[0132] The amount of each treatment and the phytotoxicity to wheat are shown in Table 5. The results of the field test show that the dichloroisonixarone and mesosulfuron-methyl composition of the present application has a phytotoxicity of 2.4% to 7.1% to wheat, and the dichloroisonixarone single agent has a phytotoxicity of 13.5% to 24.7% to wheat, and the E-E0 value is -20.2% to -11.1%, indicating that in actual application, the composition of the present application has obvious antagonistic effect on the phytotoxicity of wheat, and can significantly reduce the phytotoxicity of dichloroisonixarone single agent to wheat.

[0133] Table 5 Field test results of dichloroisonixarone and mesosulfuron-methyl combination on wheat phytotoxicity

[0134]

[0135]

[0136] The representative treatment field performance is shown in Figure 1 and Figure 2 . As can be seen from Figure 1 , 36% dichloroisonixarone suspension concentrate 216 g a.i. / hm2 After treatment, the wheat heart leaves were severely whitened and yellowed, the growth points were severely affected, the wheat growth was severely inhibited, the overall phytotoxicity was serious, and it was difficult to recover. The dosage of preparation example 4 was 220.5g a.i. / hm 2 After treatment, the wheat leaves were slightly yellowed, the growth points were not obviously affected, the overall phytotoxicity was slight, and it could recover. 2 After treatment, the wheat leaves were slightly yellowed, the growth points were not obviously affected, the overall phytotoxicity was slight, and it could recover.

[0137] The dosage of each treatment agent and the control effect on weeds in wheat field are shown in Table 6. The results of field test show that the dichloroisoniximone and mesosulfuron-methyl composition described in the present application has an E-E0 value of 15.4% to 27.6% for the overall control effect on Alopecurus aequalis and Brassica campestris in wheat field, indicating that the composition described in the present application has obvious synergistic effect on weeds in wheat field in actual application.

[0138] Table 6: Field test results of dichloroisoniximone and mesosulfuron-methyl combination on weeds in wheat field

[0139]

[0140] Therefore, the dichloroisoniximone and mesosulfuron-methyl composition described in the present application can significantly reduce the phytotoxicity to crops and improve the control effect on weeds without adding a safener, by virtue of the unique interaction mechanism of the two and the interaction mechanism of the two with crops or weeds, and is an ideal herbicide.

[0141] The present application has been described by specific examples. Those skilled in the art can appropriately change raw materials, process conditions and other aspects to achieve corresponding other purposes with reference to the content of the present application, and the related changes do not deviate from the content of the present application, all similar substitutions and modifications are considered to be included in the scope of the present application, and all similar substitutions and modifications are considered to be included in the scope of the present application. The spirit does not deviate from the present application.

Claims

1. A herbicidal composition comprising dichloroisoniximone and mesosulfuron, characterized in that, The weight ratio of the dichloroisonixappontane and mesosulfuron-methyl is 1:0.004-1.5, and the herbicidal composition does not contain a herbicide safener.

2. The herbicidal composition according to claim 1, characterized by The weight ratio of the dichloroisonixappontane and mesosulfuron-methyl is 1:0.008-0.

2.

3. The herbicidal composition according to any one of claims 1 or 2, characterized in that, The weight ratio of the dichloroisonixappontane and mesosulfuron-methyl is 1:0.02-0.

15.

4. A herbicide containing the herbicidal composition according to any one of claims 1-3.

5. The herbicide according to claim 4, characterized in that, The dichloroisonixappontane and mesosulfuron-methyl account for 5%-90% of the total weight.

6. The herbicide according to claim 5, characterized in that, The dichloroisonixappontane and mesosulfuron-methyl account for 20%-60% of the total weight.

7. The herbicide according to any one of claims 4 to 6, characterized in that, The herbicidal composition is prepared into any pesticidally acceptable dosage form selected from the group consisting of wettable powder, suspension concentrate, water dispersible granule, suspoemulsion, microemulsion, aqueous emulsion, emulsifiable concentrate, oil miscible flowable concentrate, soluble powder, dry flowable concentrate, granule, powder, aqueous agent, oil agent and microcapsule flowable concentrate.

8. Use of the herbicidal composition according to any one of claims 1-3 or the herbicide according to any one of claims 4-7 in reducing crop phytotoxicity in controlling agricultural weeds.

9. Use according to claim 8, characterized in that, The herbicidal composition and / or herbicide is used for controlling bromus japonicus and brassica campestris in wheat field. The herbicidal composition and / or herbicide is used for controlling bromus japonicus and brassica campestris in wheat field.

10. Use according to any one of claims 8-9, characterized in that, The effective component of the herbicidal composition or herbicide is used in an amount of 10-500 g / hm 2 .

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