An in vitro diagnostic test device using a fluorescent marker

By using the three-point support fixing of the limiting groove, the limiting plate and the arc-shaped seat in the in vitro diagnostic testing equipment, the problem of poor seal support is solved, and the sealing and convenience of use is improved.

CN118190891BActive Publication Date: 2025-04-11浙江基励生物科技有限公司
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Patent Information

Application Number
CN202410425404.9
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-04-10
Publication Date
2025-04-11
Estimated Expiration
2044-04-10

AI Technical Summary

Technical Problem

The seals of existing equipment for in vitro diagnostic testing using fluorescent markers cannot be effectively supported during use, and are prone to tilt and shake, resulting in poor sealing and inconvenient use.

Method used

The three-point support and fixing is formed between the limiting groove, the limiting plate and the arc seat. The arc seat horizontally slides the sealing plate horizontally on the top of the connection hole for sealing, and the extrusion limit is completed by moving the sealing plate back and forth to ensure the sealing of the top of the connection hole.

Benefits of technology

The stable support of the seal is achieved, the sealing of the connecting hole is ensured, the tilt shaking is avoided, and the convenience of the equipment is improved and the reliability of the inspection is improved.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention provides an in vitro diagnostic test device using a fluorescent marker, comprising a diagnostic test device body, the diagnostic test device body comprising a box, the top of the box is provided with an opening, a cover plate is movably installed inside the opening, one end of the box is provided with a fixing groove, and the cover plate is movably installed inside the fixing groove. The in vitro diagnostic test device using a fluorescent marker, when in use, a sealing plate is fixed by forming a three-point support between a limiting groove, a limiting plate and an arc seat, when in use, the arc seat slides horizontally to lay the sealing plate horizontally on the top of a connecting hole for sealing, and later the arc seat completes the support while allowing the sealing plate at one place to move back and forth, and the sealing plate is squeezed and limited by the back and forth movement of the sealing plate to ensure the sealing of the top of the connecting hole.
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Description

Technical Field

[0001] The present invention relates to the field of in vitro diagnostic test equipment, in particular to an in vitro diagnostic test equipment using a fluorescent marker. Background Art

[0002] In vitro diagnostics refers to products and services that obtain clinical diagnostic information by testing human samples (blood, body fluids, tissues, etc.) outside the human body, and then judge diseases or body functions. Fluorescent markers are one of the technologies for in vitro diagnostic testing. The diagnostic test device usually adds the sample to be tested into the sample addition area. After the sample reacts and mixes with other reagents pre-stored in the sample addition library, it flows through the sample reaction barrier, reaction chamber and time gate, arrives at the diagnostic unit for reaction, and finally flows into the used reagent library.

[0003] According to the patent document with the existing publication number CN117347339A, an in vitro diagnostic test device using fluorescent markers is disclosed, which includes a device body and a seal, wherein the device body is provided with a sample adding part, a diagnostic unit and a reagent reservoir; the sample adding part is connected to the reagent reservoir through the diagnostic unit; the seal is detachably connected to the device body, and the seal is used to be removed from the device body after the substance to be tested reacts with the corresponding biochemical substance and the tracer reagent, so that the external sensor can detect the signal generated by the diagnostic unit, the diagnostic unit includes a fluid channel, and the sample adding part is connected to the reagent reservoir through the fluid channel. When the technical solution is used, the seal can be removed to perform detection, so as to achieve detection without interference, thereby effectively improving the ability and reliability of detecting trace substances. With respect to the above technical solution, although the solution provides the ability of detection through the seal, the seal cannot be effectively supported during use, and tilts and shakes during use, resulting in ineffective sealing, which is inconvenient during use. Summary of the invention

[0004] In view of the shortcomings of the prior art, the purpose of the present invention is to provide an in vitro diagnostic test device using fluorescent markers to solve the problems raised in the above-mentioned background technology. The present invention has a novel structure. When in use, the sealing plate is fixed by forming three-point support between the limit groove, the limit plate and the arc seat. When in use, the arc seat slides horizontally to lay the sealing plate horizontally on the top of the connecting hole for sealing. Later, the arc seat can complete the support and extrusion limit of the sealing plate at the same time to ensure the sealing of the top of the connecting hole.

[0005] In order to achieve the above-mentioned purpose, the present invention is implemented through the following technical scheme: an in vitro diagnostic test device using fluorescent markers, comprising a diagnostic test device body, the diagnostic test device body comprising a box body, the top of the box body is provided with an opening, a cover plate is movably installed inside the opening, one end of the box body is provided with a fixing groove, the cover plate is movably installed inside the fixing groove, a movable seat and a fixed seat are respectively installed at the bottom of the box body, the fixed seat is fixedly installed at the bottom of the box body, a slide groove is provided on the side of the box body, and a slider is movably installed inside the slide groove.

[0006] Furthermore, a movable plate is fixed to one end of the sliding block, and a protrusion is fixed to the side of the movable plate.

[0007] Furthermore, a fixed box is fixedly installed inside the box body, an opening is opened on the fixed box, and a reagent storage is installed inside the fixed box.

[0008] Furthermore, a sealing plate is movably installed inside the box body, a limiting groove is formed at one end of the cover plate, and one end of the sealing plate is movably installed inside the limiting groove.

[0009] Furthermore, fixed blocks are fixed on the inner wall of the movable plate, and arc seats are fixedly installed between the fixed blocks.

[0010] Furthermore, a connecting hole is opened on the inner wall of the box body, a through hole is opened on the inner wall of the connecting hole, and a connecting groove is opened between the connecting holes.

[0011] Furthermore, a limiting plate is welded on the inner wall of the box body, a mounting hole is opened at the bottom of the box body, and a limiting hole is opened at one end of the mounting hole.

[0012] Furthermore, a limiting column is movably installed inside the installation hole and the limiting hole, and an extrusion plate is fixed to one end of the limiting column, and the extrusion plate cooperates with the limiting plate.

[0013] Furthermore, a support mechanism is fixed on the inner wall of the mounting hole, one end of the support mechanism is fixed on the extrusion plate, and the other end of the limiting column is fixed on the movable seat.

[0014] Furthermore, the arc seat is movably matched with the sealing plate, and the fixed block is movably installed inside the slide groove.

[0015] Beneficial effects of the present invention: The present invention is an in vitro diagnostic test device using fluorescent markers, comprising a box body; an opening; a cover plate; a movable seat; a fixed seat; a movable plate; a protrusion; a fixed box; an opening; a sealing plate; a slide groove; a slider; a connecting hole; a through hole; a connecting groove; a fixed block; an arc seat; a fixing groove; a limit groove; a limit plate; a mounting hole; a limit hole; a limit column; a support mechanism; and an extrusion plate.

[0016] 1. This is an in vitro diagnostic test device that uses fluorescent markers. When in use, the sealing plate is fixed by forming three-point support between the limit groove, the limit plate and the arc seat. When in use, the arc seat slides horizontally to lay the sealing plate horizontally on the top of the connecting hole for sealing. Later, the arc seat completes the support while allowing the sealing plate at one place to move back and forth. The back and forth movement of the sealing plate completes the extrusion and limitation of the sealing plate to ensure the sealing of the top of the connecting hole.

[0017] 2. This is an in vitro diagnostic test device that uses fluorescent markers. The cover plate blocks and seals the entire box when the device is not in use. When in use, one end of the sealing plate is limited inside the limiting groove. The limiting groove provides a support limiting point for the sealing plate. The subsequent movement of the cover plate allows the sealing plate to be quickly separated from the limiting groove, which makes it easy to quickly remove the sealing plate from the inside of the box.

[0018] 3. This is an in vitro diagnostic test device using fluorescent markers. One end of the sealing plate is placed between the extrusion plate and the limit plate. When the box is placed on the desktop, the movable seat is squeezed by the pressure of the box itself. The extrusion plate on the movable seat moves upward to complete the extrusion and fixation of one end of the sealing plate. In the later stage, the fixed seat and the movable seat are misaligned up and down. After the misalignment, the box as a whole is tilted to facilitate the flow of internal liquid. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 This is a schematic diagram of the structure of an in vitro diagnostic test device using a fluorescent marker according to the present invention;

[0020] Figure 2 This is a schematic structural diagram of an in vitro diagnostic test device using a fluorescent marker after the sealing plate is installed;

[0021] Figure 3 This is a schematic structural diagram of an in vitro diagnostic test device using a fluorescent marker after a sealing plate is removed according to the present invention;

[0022] Figure 4 A schematic diagram of the three-dimensional structure of an arc-shaped seat of an in vitro diagnostic test device using a fluorescent marker according to the present invention;

[0023] Figure 5 This is a schematic diagram of the side cross-sectional structure of a box of an in vitro diagnostic test device using a fluorescent marker according to the present invention;

[0024] In the figure: 1. box body; 2. opening; 3. cover plate; 4. movable seat; 5. fixed seat; 6. movable plate; 7. protrusion; 8. fixed box; 9. opening; 10. sealing plate; 11. slide groove; 12. slider; 13. connecting hole; 14. through hole; 15. connecting groove; 16. fixed block; 17. arc seat; 18. fixed groove; 19. limit groove; 20. limit plate; 21. mounting hole; 22. limit hole; 23. limit column; 24. support mechanism; 25. extrusion plate. DETAILED DESCRIPTION

[0025] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further explained below in conjunction with specific implementation methods.

[0026] See also Figures 1 to 5 The present invention provides a technical solution: an in vitro diagnostic test device using a fluorescent marker, comprising a diagnostic test device body, the diagnostic test device body comprising a box body 1, the top of the box body 1 is provided with an opening 2, a cover plate 3 is movably installed inside the opening 2, one end of the box body 1 is provided with a fixing groove 18, the cover plate 3 is movably installed inside the fixing groove 18, a movable seat 4 and a fixed seat 5 are respectively installed at the bottom of the box body 1, the fixed seat 5 is fixedly installed at the bottom of the box body 1, a slide groove 11 is provided on the side of the box body 1, a slider 12 is movably installed inside the slide groove 11, when the box body 1 is placed on a desktop, the movable seat 4 is squeezed by the pressure of the box body 1 itself, and the squeezing plate 25 on the movable seat 4 moves upward to complete the squeezing and fixing of one end of the sealing plate 10, and the fixed seat 5 and the movable seat 4 are displaced up and down in the later stage, and the box body 1 is tilted as a whole after the dislocation, which is convenient for the flow of the internal liquid.

[0027] In this embodiment, a movable plate 6 is fixed to one end of the slider 12, a protrusion 7 is fixed to the side of the movable plate 6, a fixed box 8 is fixedly installed inside the box body 1, an opening 9 is opened on the fixed box 8, a reagent reservoir is installed inside the fixed box 8, a sealing plate 10 is movably installed inside the box body 1, a limiting groove 19 is opened at one end of the cover plate 3, one end of the sealing plate 10 is movably installed inside the limiting groove 19, the through holes 14 are connected in a U-shape, one end of the U-shaped pipe is connected to the reagent reservoir, and when in use, the limiting plate 20 provides an upward limiting force for one end of the sealing plate 10 to avoid loosening caused by the upward tilting of the sealing plate 10.

[0028] In this embodiment, a fixing block 16 is fixed on the inner wall of the movable plate 6, an arc seat 17 is fixedly installed between the fixing blocks 16, a connecting hole 13 is opened on the inner wall of the box body 1, a through hole 14 is opened on the inner wall of the connecting hole 13, a connecting groove 15 is opened between the connecting holes 13, a limiting plate 20 is welded on the inner wall of the box body 1, a mounting hole 21 is opened at the bottom of the box body 1, a limiting hole 22 is opened at one end of the mounting hole 21, and the connecting groove 15 and the connecting hole 13 cooperate with each other to facilitate the flow of liquid inside the connecting holes 13 and the through holes 14 at different positions.

[0029] In this embodiment, a limiting column 23 is movably installed inside the mounting hole 21 and the limiting hole 22, and an extrusion plate 25 is fixed at one end of the limiting column 23, and the extrusion plate 25 cooperates with the limiting plate 20. A supporting mechanism 24 is fixed on the inner wall of the mounting hole 21, and one end of the supporting mechanism 24 is fixed on the extrusion plate 25, and the other end of the limiting column 23 is fixed on the movable seat 4. The arc seat 17 is movably coordinated with the sealing plate 10, and the fixed block 16 is movably installed inside the slide groove 11. The supporting mechanism 24 is a supporting spring. After the box body 1 moves upward, the box body 1 loses the extrusion on the movable seat 4, and the extrusion plate 25 is driven to shrink inside the mounting hole 21 under the pulling of the supporting mechanism 24, and the extrusion force on one end of the sealing plate 10 is lost.

[0030] When the device is in use, the cover plate 3 is first moved inside the fixing groove 18, and the position of the fixing box 8 is exposed as the cover plate 3 moves, and the position of the connecting hole 13 inside the box body 1 is opened with one end of the cover plate 3. After opening, the sealing plate 10 is preferentially installed inside the box body 1. When the sealing plate 10 is installed, one end of the sealing plate 10 passes through the bottom of the arc seat 17, and one end of the sealing plate 10 is installed at the bottom of the limiting plate 20. After one end of the sealing plate 10 is installed at the bottom of the limiting plate 20, the box body 1 is placed on the desktop, or the movable seat 4 is directly moved upward by hand. After the sealing plate 10 is fixed, the movable plate 6 is slid inside the slide groove 11, and the movable plate 6 drives the arc seat 17 to slide toward the position of the fixed box 8 through the fixed block 16, and the sealing plate 10 is laid on the top of the connecting hole 13. When the arc seat 17 moves to one side of the fixed box 8 in the later stage, the arc seat 17 stops moving, and the arc seat 17 provides secondary support for the sealing plate 10. The position of one end of the top of the plate 10 is adjusted by adjusting the position of the cover plate 3 on the top of the box body 1, and the cover plate 3 is moved inside the fixing groove 18, and one end of the sealing plate 10 is moved to enter the limiting groove 19, and the limiting groove 19 completes the re-limiting fixation of one end of the sealing plate 10, and the reagent to be tested is dripped into the opening 9, and enters the through hole 14 and the connecting hole 13 along with the opening 9. The through hole 14 and the connecting hole 13 are equipped with a diagnostic unit, and one end of the diagnostic unit is connected to the reagent reservoir. The reagent passes through the diagnostic unit in turn and enters the inside of the reagent reservoir to complete the reagent reaction. Finally, move the cover plate 3 in the opposite direction of the fixed box 8 to separate the limiting groove 19 from the sealing plate 10, and pull the sealing plate 10 out from between the arc seat 17 and the limiting plate 20. After being pulled out, the diagnostic unit is completely exposed. The sealing plate 10 is a flexible sealing paper sheet. When in use, the arc seat 17 slides horizontally to lay the sealing plate 10 horizontally on the top of the connecting hole 13 for sealing. Later, the arc seat 17 completes the support while allowing the sealing plate 10 at one place to move back and forth. The back and forth movement of the sealing plate 10 completes the extrusion and limiting of the sealing plate 10 to ensure the sealing of the top of the connecting hole 13.

[0031] The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. It is obvious to those skilled in the art that the present invention is not limited to the details of the above exemplary embodiments, and the present invention can be implemented in other specific forms without departing from the spirit or basic features of the present invention. Therefore, no matter from which point of view, the embodiments should be regarded as exemplary and non-restrictive. The scope of the present invention is defined by the attached claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims are included in the present invention. Any figure mark in the claims should not be regarded as limiting the claims involved.

[0032] In addition, it should be understood that although the present specification is described according to implementation modes, not every implementation mode contains only one independent technical solution. This description of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment may also be appropriately combined to form other implementation modes that can be understood by those skilled in the art.

Claims

1. An in vitro diagnostic test device using a fluorescent marker, comprising a diagnostic test device body, characterized in that: The diagnostic test device body comprises a box (1), the top of the box (1) is provided with an opening (2), a cover plate (3) is movably installed inside the opening (2), one end of the box (1) is provided with a fixing groove (18), the cover plate (3) is movably installed inside the fixing groove (18), the bottom of the box (1) is respectively provided with a movable seat (4) and a fixed seat (5), the fixed seat (5) is fixedly installed at the bottom of the box (1), a sliding groove (11) is provided on the side of the box (1), a sliding block (12) is movably installed inside the sliding groove (11), a movable plate (6) is fixed at one end of the sliding block (12), a protrusion (7) is fixed on the side of the movable plate (6), a sealing plate (10) is movably installed inside the box (1), a limiting groove (19) is provided at one end of the cover plate (3), one end of the sealing plate (10) is movably installed inside the limiting groove (19), and a fixing block (16) is fixed on the inner wall of the movable plate (6). An arc seat (17) is fixedly installed between the fixing blocks (16), a limit plate (20) is welded on the inner wall of the box body (1), a mounting hole (21) is opened at the bottom of the box body (1), a limit hole (22) is opened at one end of the mounting hole (21), a limit column (23) is movably installed inside the mounting hole (21) and the limit hole (22), an extrusion plate (25) is fixed at one end of the limit column (23), and the extrusion plate (25) matches the limit plate (20). A support mechanism (24) is fixed on the inner wall of the mounting hole (21), one end of the support mechanism (24) is fixed on the extrusion plate (25), the other end of the limit column (23) is fixed on the movable seat (4), the arc seat (17) is movably matched with the sealing plate (10), the fixed block (16) is movably mounted inside the slide groove (11), and the sealing plate (10) is supported and fixed at three points by the limit groove (19), the limit plate (20) and the arc seat (17).

2. The in vitro diagnostic test device using fluorescent markers according to claim 1, characterized in that: A fixed box (8) is fixedly installed inside the box body (1), an opening (9) is opened on the fixed box (8), and a reagent storage is installed inside the fixed box (8).

3. The in vitro diagnostic test device using fluorescent markers according to claim 1, characterized in that: The inner wall of the box body (1) is provided with a connection hole (13), the inner wall of the connection hole (13) is provided with a through hole (14), and connection grooves (15) are provided between the connection holes (13).

Citation Information

Patent Citations

  • Devices for in vitro diagnostic tests using fluorescent markers

    CN117347339A

  • Process to apply a self-adhesive seal to an automotive roof for a sliding hatch using industrial robot

    DE102007033363A1