A preparation method of an extract of a processed product of polygala for treating uremia

By clarifying the processing parameters of Polygala tenuifolia prepared with Evodia rutaecarpa juice, the problems of reduced effective components and gastrointestinal toxicity in processed Polygala tenuifolia products were solved, providing a highly effective treatment plan for uremia and achieving stronger medicinal effects and reduced gastrointestinal toxicity.

CN118236420BActive Publication Date: 2026-07-03LIAONING UNIV OF TRADITIONAL CHINESE MEDICINE
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
LIAONING UNIV OF TRADITIONAL CHINESE MEDICINE
Filing Date
2024-04-16
Publication Date
2026-07-03

AI Technical Summary

Technical Problem

The existing processing technology for Polygala tenuifolia lacks clear parameters for processing Evodia rutaecarpa juice, which leads to a reduction in its effective components and may affect its efficacy. Furthermore, Polygala tenuifolia has gastrointestinal toxicity, and long-term or excessive use can damage gastrointestinal function, and there is a lack of effective detoxification measures.

Method used

The extract was prepared by mixing Evodia rutaecarpa juice with Polygala tenuifolia slices, then soaking, stir-frying and drying, followed by decoction twice with water and concentration. The parameters such as the ratio of material to liquid, stir-frying temperature and time were determined to form Polygala tenuifolia processed product made from Evodia rutaecarpa juice.

Benefits of technology

This method improves the therapeutic effect of processed Polygala tenuifolia on uremia, reduces gastrointestinal toxicity, and provides more significant medicinal value. The process is simple and inexpensive.

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Abstract

This invention belongs to the technical field of traditional Chinese medicine preparation methods, specifically relating to a method for preparing a processed Polygala tenuifolia extract for treating uremia. The preparation method includes step 1: mixing cleaned Polygala tenuifolia slices with Evodia rutaecarpa juice, allowing the mixture to soak and absorb the juice completely, then stir-frying and drying to obtain processed Polygala tenuifolia prepared with Evodia rutaecarpa juice; step 2: soaking the above processed Polygala tenuifolia in pure water, decocting twice, combining the two filtrates, and concentrating the decoction to a concentration of 0.9429 g / ml to obtain the processed Polygala tenuifolia extract. This preparation method clarifies the processing technology of processed Polygala tenuifolia prepared with Evodia rutaecarpa juice and its efficacy in treating uremia, providing a foundation for new drug development. The processed Polygala tenuifolia extract obtained by this method has a good therapeutic effect on uremia.
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