Reagent container storage device, reagent interaction module, sample analyzer and system
By designing a reagent container storage device and using the switching of locking and unlocking positions to achieve synchronous connection and separation between the reagent needle and the container, the problem of cumbersome reagent replacement process and human contact risk in hematology analyzers is solved, thus realizing safe and convenient reagent replacement.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- ZYBIO INC
- Filing Date
- 2024-01-30
- Publication Date
- 2026-07-03
AI Technical Summary
The existing process of changing fluorescent dyes and reagents in hematology analyzers is cumbersome and poses a risk of human contact, leading to pollution and harm.
Design a reagent container storage device, including a reagent container housing and a storage chamber, to enable communication or separation between the reagent needle and the reagent container through locking and unlocking positions, and to ensure safe loading and replacement of the reagent container by combining a positioning structure and a guide groove.
It ensures the safety and ease of reagent replacement, reduces the risk of human contact with reagents, and simplifies the operation process.
Smart Images

Figure CN118618727B_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of blood analysis technology, and in particular to a reagent container storage device, a reagent interaction module, a sample analyzer and system. Background Technology
[0002] A hematology analyzer is a medical device used to detect the number and type of white blood cells in the blood. It measures indicators such as the number of white blood cells, white blood cell types, and platelet count. Important reagents used in conjunction with the hematology analyzer include fluorescent dyes, which contain a fluorescent dye that binds to certain proteins or molecules in the blood, thereby enhancing their fluorescence signal. This reagent improves the sensitivity and accuracy of the hematology analyzer, helping doctors to diagnose and treat diseases more accurately. However, fluorescent dyes are toxic and should not be touched directly by hand; moreover, some manufacturers' reagents are designed to be kept out of air. When using fluorescent dyes in a hematology analyzer, it is essential to follow the correct operating procedures and instructions to minimize harm to the human body. However, the current process for changing fluorescent dyes is cumbersome, and accidental contact with the reagent is easy. The reagent bags are delicate, and handling them by hand can either contaminate the reagent or cause harm to the human body.
[0003] For example, some solutions use aluminum foil bags located on the front of the front panel. The front panel is flipped down to open, and the reagents are contained in the aluminum foil bags. The aluminum foil bags are hung on a sheet metal bracket via a suction nozzle. The person holding the aluminum foil bag touches the suction nozzle and the cap, manually rotating the cap to clamp it to the sheet metal bracket or remove and replace it. After securing it, a steel needle connected to the tubing is inserted downwards into the suction nozzle of the aluminum foil bag, and finally the front panel is closed. The reagent replacement process involves contact with the bag opening area, and the steel needle punctures through this area, easily causing reagent contamination. Even a slight leak at the bag opening area can come into contact with the person's hands, posing a health risk.
[0004] For example, in other solutions, reagent bottles are used, but it is necessary to manually use a needle to puncture the seal of the reagent bottle or use a mechanism-assisted sliding needle to puncture the seal of the reagent bottle. Puncture of the reagent bottle seal may be mistaken, resulting in the needle pricking the hand, harming the body and contaminating the reagent.
[0005] Currently, the reagent replacement process in various models is complex and involves many steps, and there is a risk of human contact with the reagents. Therefore, there is an urgent need for a reagent replacement structure that is both safe and easy to use. Summary of the Invention
[0006] In view of the shortcomings of the prior art described above, the object of the present invention is:
[0007] Firstly, a reagent container storage device is provided, the key feature of which is that it includes:
[0008] A reagent container holder, wherein the reagent container holder is provided with a receiving cavity for receiving reagent containers;
[0009] A storage chamber, wherein the storage chamber has at least one receiving space inside, the storage chamber has an assembly port, and a reagent needle is fixed inside the receiving space;
[0010] The reagent container is movably installed in the storage chamber and extends into the accommodating space along the first direction;
[0011] The storage chamber has a locking position and an unlocking position. When the reagent container is in the locking position, the reagent needle is in communication with the reagent container; when the reagent container is in the unlocking position, the reagent needle is separated from the reagent container.
[0012] In conjunction with the first aspect, in some implementations, the storage chamber also has a replacement position, whereby the reagent container is placed or removed when it is located in the replacement position.
[0013] In conjunction with the first aspect, in some implementations, the reagent container includes a positioning structure, and the reagent container is provided with a fixing structure corresponding to the positioning structure. The fixing structure cooperates with the positioning structure to position and fix the reagent container in the receiving cavity.
[0014] In conjunction with the first aspect, in some implementations, the positioning structure is a U-shaped card interface, the fixing structure is inserted into the U-shaped card interface, and the fixing structure is limited in the first direction.
[0015] In conjunction with the first aspect, in some implementations, the receiving cavity of the reagent container has an opening for loading or unloading the reagent container along a second direction, the second direction being perpendicular to the first direction.
[0016] In conjunction with the first aspect, in some implementations, the accommodating space is provided with a guide groove for directionally guiding the reagent container container to be loaded into or unloaded from the accommodating space. The guide groove extends along the first direction. The bottom of the reagent container container is also provided with a guide seat. The guide seat is provided with a sliding shaft for cooperating with the guide groove and sliding in a directional manner. The sliding shaft is located near the front end of the guide seat.
[0017] In conjunction with the first aspect, in some implementations, the reagent container housing has a first marking on the side opposite to the positioning structure. The reagent container housing also includes a cooling module for controlling the reagents within the reagent container within a preset temperature range.
[0018] In conjunction with the first aspect, in some implementations, the storage chamber includes at least three accommodating spaces, each of which corresponds to the installation of one of the reagent container accommodating boxes.
[0019] In conjunction with the first aspect, in some implementations, the reagent container is located in the storage chamber, and the reagent container is switched between a locked position and an unlocked position by pressing the reagent container.
[0020] In conjunction with the first aspect, in some implementations, the storage chamber is further provided with a locking tongue unit, and the reagent container is provided with a locking unit that cooperates with the locking tongue unit, and the locking tongue unit provides a first elastic force to the locking unit;
[0021] When the reagent container is pressed, the locking tongue unit is connected to the locking unit via a first elastic force, and the reagent container is in the locked position; pressing the reagent container provides a force to overcome the first elastic force, releasing the connection between the locking tongue unit and the locking unit, and the reagent container is in the unlocked position.
[0022] In conjunction with the first aspect, in some implementations, a motion locking chamber is provided below the accommodating space, and the locking tongue unit is disposed within the motion locking chamber. The locking tongue unit includes a base, a protrusion disposed on the base, and an elastic part connected to the protrusion. One end of the elastic part is fixed to the protrusion, and the other end extends in a first direction. When the elastic part is subjected to a downward compressive force, it provides an upward first elastic force. When the reagent container is inserted into the locking position in the storage chamber, the elastic part is connected to the locking unit under the action of the first elastic force; the protrusion abuts against and is positioned with the reagent container.
[0023] In conjunction with the first aspect, in some implementations, the base is reciprocated in the first direction, the storage chamber is provided with a hook and a first elastic element, the tail of the hook is fixed in the first direction, the head of the hook hooks the base in the initial or locked position along the first direction, and the first elastic element provides a reset elastic force to the base in the opposite direction of the first direction.
[0024] The reagent container is inserted into the storage chamber and pushes the base to move along the first direction to the locking position. The head of the hook moves from the initial position of the base to the locking position and hooks the locking position. The hook and the reset force of the first elastic element are balanced. The reagent container is unlocked and exits the locking position along the first direction. The head of the hook disengages from the locking position and moves to the initial position under the reset force of the first elastic element. The base pushes the reagent container to pop out from the locking position.
[0025] In conjunction with the first aspect, in some implementations, the initial position and the locked position are connected by a first slide and a second slide, the first slide and the second slide are connected end to end, the head of the hook moves from the initial position to the locked position along the first slide and is fixed at a fixed point in the locked position, and moves from the locked position to the initial position along the second slide and is fixed at a fixed point in the initial position.
[0026] In conjunction with the first aspect, in some implementations, along the direction of movement of the hook head, the first and second slides are sequentially divided into a first segment, a second segment, a third segment, and a fourth segment. The connection between the first and second segments serves as a first inflection point, used to guide the hook head to move towards the second segment. The second and third segments combine to form a "V"-shaped slide, the curved portion of the "V"-shaped slide serves as the locking position, and the connection between the third and fourth segments serves as a second inflection point, used to guide the hook head to move towards the fourth segment. The starting end of the first segment and the ending end of the fourth segment converge to form the starting position.
[0027] In conjunction with the first aspect, in some implementations, from the starting end of the first segment to the bend, the depth of the first slide rail first decreases and then increases after reaching the first inflection point; from the bend to the ending end of the fourth segment, the depth of the second slide rail first decreases and then increases after reaching the second inflection point.
[0028] In conjunction with the first aspect, in some implementations, the curved portion of the "V"-shaped slide includes a locking portion with a concave sidewall and a guide portion with a protruding sidewall. When the hook is in the locking position, the head of the hook hooks onto the locking portion, the head of the hook retracts from the locking portion, and the guide portion guides the head of the hook to shift towards the third segment.
[0029] In conjunction with the first aspect, in some implementations, a support partition for supporting the reagent container is provided between the motion locking chamber and the accommodating space. The support partition has a guide hole extending in a first direction, and the base is configured to reciprocate in the first direction by engaging with the guide hole through the protrusion.
[0030] In conjunction with the first aspect, in some implementations, the lower side of the supporting partition is provided with a guide rail extending along a first direction, and the base is provided with a directional sliding groove, the base sliding in cooperation with the guide rail through the directional sliding groove.
[0031] In conjunction with the first aspect, in some implementations, a second elastic element is provided below the base, the second elastic element provides a second elastic force to the hook, the second elastic force pushes the hook toward the base.
[0032] In conjunction with the first aspect, in some implementations, the support partition extends to the assembly port, and the support partition is provided with a guide slope at the assembly port.
[0033] In conjunction with the first aspect, in some implementations, the motion locking chamber is equipped with a micro switch for determining whether the reagent container holder is in the locking position.
[0034] In conjunction with the first aspect, in some implementations, multiple ribs are provided on the inner wall of the accommodating space, the ribs extend along a first direction, and the multiple ribs are evenly and parallelly distributed in a direction perpendicular to the first direction.
[0035] In conjunction with the first aspect, in some implementations, the locking unit includes a locking hole disposed on the guide seat.
[0036] In conjunction with the first aspect, in some implementations, the reagent container includes a reagent bottle or a reagent bag.
[0037] In conjunction with the first aspect, in some implementations, the reagent container includes at least one for containing latex reagent, hemolytic reagent, diluent reagent, or fluorescent reagent.
[0038] In conjunction with the first aspect, in some implementations, the reagent container further includes a refrigeration module for controlling the reagents within the reagent container within a preset temperature range.
[0039] Secondly, a reagent container is provided, the key feature of which is: it includes a nozzle and a body, the nozzle is provided with a reagent puncture part for reagent needle puncture, and the neck of the nozzle is provided with a fixing structure for cooperating and fixing with a reagent receiving box, the fixing structure includes a front limiting block, a rear limiting block and a connecting block connected between the front limiting block and the rear limiting block, the front limiting block, the rear limiting block and the connecting block are combined to form an I-shape.
[0040] In conjunction with the second aspect, in some implementations, the device body is provided with a liquid accumulation section, which is located near the suction nozzle, and both the suction nozzle and the liquid accumulation section are located at the bottom of the device body in the direction of gravity.
[0041] Thirdly, the use of the reagent container storage device described in any implementation of the first aspect is provided, the key point being: a storage device as a container for storing fluorescent reagents.
[0042] Fourthly, a reagent interaction module is provided, the key feature of which is: it includes multiple reagent container storage devices connected side by side, wherein the reagent container storage devices are the reagent container storage devices described in any implementation of the first aspect.
[0043] In conjunction with the fourth aspect, in some implementations, a gap-blocking plate is provided on the surface where the assembly port of the reagent container storage device is located. The gap-blocking plate connects the reagent container storage devices and blocks the gaps between the reagent container storage devices. The gap-blocking plate has an assembly hole corresponding to the assembly port of each reagent container storage device.
[0044] In conjunction with the fourth aspect, in some implementations, an electronic tag board and an antenna board are provided on the rear side away from the assembly port of the reagent container storage device.
[0045] In conjunction with the fourth aspect, in some implementations, the bottom surface of the reagent interaction module is fixedly provided with a mounting plate.
[0046] Fifthly, a sample analyzer is provided, the key feature of which is that it includes the reagent interaction module described in any of the implementations of the fourth aspect.
[0047] Sixthly, a sample analysis system is provided, the key of which includes:
[0048] A detection subsystem, the detection subsystem including a reaction tank;
[0049] A reagent container storage device, wherein the reagent container storage device is the reagent container storage device in any implementation of the first aspect, wherein the storage chamber is provided with at least two accommodating spaces, and the reagent container accommodating box is provided one-to-one with the accommodating space;
[0050] The reagent management subsystem is used to control the supply of reagents and the loading and / or replacement of reagent containers.
[0051] In conjunction with the sixth aspect, in some implementations, the sample analysis system further includes an information reading module for reading information about the reagent container.
[0052] In conjunction with the sixth aspect, in some implementations, the information reading module includes an information reading unit capable of simultaneously reading information from multiple reagent container boxes; the reagent management subsystem is communicatively connected to the information reading module.
[0053] In conjunction with the sixth aspect, in some implementations, the information reading module includes multiple information reading units, each of which is configured one-to-one with the reagent container, and the reagent management subsystem is communicatively connected to the information reading module.
[0054] In conjunction with the sixth aspect, in some implementations, when receiving reagent loading and / or reagent replacement instructions, the reagent management subsystem controls the information reading unit to initiate information reading.
[0055] In conjunction with the sixth aspect, in some implementations, the reagent management subsystem is also used to judge the information read by the information reading unit;
[0056] If the read information is deemed correct, a normal signal is output.
[0057] If the read information is deemed invalid, an alarm signal is output.
[0058] In conjunction with the sixth aspect, in some implementations, the reagent management subsystem determines the information read by the information reading unit by judging whether a label is present, whether it is within its expiration period, and one or more types of reagents.
[0059] In conjunction with the sixth aspect, in some implementations, the determination of the information read by the information reading unit by the reagent management subsystem includes a first determination, and if the first determination is yes, it also includes a second determination;
[0060] If the second judgment is correct, a normal signal is output and the read information is stored in the sample analysis system;
[0061] If the second judgment is negative, an alarm signal is output.
[0062] In conjunction with the sixth aspect, in some implementations, if the second judgment is correct, a normal signal is output and a confirmation message is displayed; after receiving the confirmation instruction, the information read by the information reading unit is stored in the sample analysis system and a success signal is output.
[0063] In conjunction with the sixth aspect, in some implementations, the reagent management subsystem is also used to judge and store the information read by the information reading unit;
[0064] If the read information is deemed correct, a normal signal is output and the read information is stored in the sample analysis system.
[0065] If the read information is deemed invalid, an alarm signal is output.
[0066] In conjunction with the sixth aspect, in some implementations, when the read information is determined to be correct, a normal signal is output and a confirmation message is displayed; after receiving the confirmation instruction, the read information is stored in the sample analysis system and a success signal is output.
[0067] In conjunction with the sixth aspect, in some implementations, when a confirmation instruction for reagent loading and / or reagent replacement is received, the reagent management subsystem controls the reagent container to switch from the locked position to the unlocked position.
[0068] In conjunction with the sixth aspect, in some implementations, when a reagent loading success, reagent anomaly elimination, and / or reagent replacement success instruction or signal is received, the reagent management subsystem controls the information reading unit to close the information reading.
[0069] In conjunction with the sixth aspect, in some implementations, when a reagent loading, reagent malfunction, and / or reagent replacement instruction is received, the reagent management subsystem activates the reagent operation interface.
[0070] In conjunction with the sixth aspect, in some implementations, when a reagent management subsystem receives an instruction or signal indicating successful reagent loading, reagent anomaly elimination, and / or successful reagent replacement, it starts and closes the reagent operation interface.
[0071] In conjunction with the sixth aspect, in some implementations, the information reading unit includes multiple reading areas, which can simultaneously read and display multiple RFID tags.
[0072] When the received "reagent loading and / or reagent replacement instruction" is for a portion of the reagent container holders (e.g., only FN has a replacement instruction, while FR and FD are normal), the reagent management subsystem controls the information reading unit to only activate the information reading area of the reagent container holder corresponding to the instruction.
[0073] In conjunction with the sixth aspect, in some implementations, the reagent management subsystem controls the information reading unit to only activate the information reading area of the reagent container corresponding to the instruction, and only displays the reading information of the reagent container corresponding to the instruction.
[0074] As described above, the reagent container storage device and sample analysis system of the present invention have at least the following beneficial effects:
[0075] In the reagent container storage device, the reagent container and the storage chamber are pushed in or out in a drawer-like combination. The reagent container can be locked in the locking position and unlocked in the unlocking position of the storage chamber. When the reagent container is pushed in to lock or released to unlock, the reagent needle is simultaneously connected or separated from the reagent container. The loading or replacement operation of the reagent container is carried out simultaneously with the connection or separation operation of the reagent needle, making reagent loading or replacement easier and more convenient, and the replacement process safer.
[0076] In the sample analysis system, the detection subsystem is used for the reaction between reagents and samples. Based on the reagent container storage device, when reagents need to be actively loaded or replaced with new reagents, the reagent management subsystem can detect whether reagents need to be loaded or replaced, and assist the reagent container storage device in confirming and identifying relevant information about newly loaded or replaced reagents, ensuring successful loading or replacement of reagents, and further simplifying the reagent loading or replacement operation process. Attached Figure Description
[0077] Figure 1 This is a schematic diagram of the structure of a sample analyzer according to an exemplary embodiment of the present invention;
[0078] Figure 2 This is a schematic diagram of the structure of a reagent interaction module from a frontal view, as shown in an exemplary embodiment of the present invention.
[0079] Figure 3 This is a perspective view of the rear of a reagent interaction module, as shown in an exemplary embodiment of the present invention.
[0080] Figure 4 for Figure 2 A picture of someone who is angry;
[0081] Figure 5 for Figure 4 Exploded view of the reagent container storage device;
[0082] Figure 6 for Figure 5 Schematic diagram of the middle locking tongue unit;
[0083] Figure 7 This is a schematic diagram of the assembly of the right shell and the reagent container box;
[0084] Figure 8 for Figure 7 A bottom view;
[0085] Figure 9-1 A simplified diagram showing the initial and locked positions of the base from the bottom view, as well as the positional relationship between the first and second slide rails;
[0086] Figure 9-2 This is a plan view of the first and second slides;
[0087] Figure 9-3 Detailed structural diagrams of the first, second, third, and fourth sections of the slide;
[0088] Figure 9-4 Detailed structural diagrams of the first, second, third, and fourth sections of the slide;
[0089] Figure 10 for Figure 7 A three-dimensional image;
[0090] Figure 11 for Figure 10 A three-dimensional diagram viewed from below;
[0091] Figure 12 A schematic diagram of the structure inside the lower motion locking chamber for assembling the second elastic element;
[0092] Figure 13This is a schematic diagram of the right shell structure;
[0093] Figure 14 This is a schematic diagram of the left shell structure;
[0094] Figure 15 A diagram showing the state changes of the reagent container as it exits the right shell.
[0095] Figure 16 This is a schematic diagram of the reagent container box.
[0096] Figure 17 This is an internal cross-sectional view of the reagent container housing.
[0097] Figure 18 This is a schematic diagram of the reagent bag structure;
[0098] Figure 19 This is a three-dimensional view of the reagent container housing and guide seat assembly;
[0099] Figure 20 for Figure 19 A three-dimensional view of the bottom surface of the center guide seat;
[0100] Figure 21 A flowchart illustrating a reagent loading method in a sample analyzer, as shown in an exemplary embodiment of the present invention.
[0101] Figure 22 A flowchart illustrating a reagent replacement method in a sample analyzer, as shown in an exemplary embodiment of the present invention.
[0102] Figure 23 This is a flowchart illustrating a reagent replacement method in a sample analyzer, as shown in another exemplary embodiment of the present invention.
[0103] The accompanying figure is labeled as follows:
[0104] 1. Housing; 3. Reagent interaction module; 2. Reagent container storage device; 4. Seam-sealing plate; 5. Assembly hole 401; 6. Electronic tag board; 7. Antenna board; 8. Mounting plate.
[0105] The reagent container includes a container box 301, a storage chamber 302, a reagent puncture site 303, a receiving space 304, a motion locking chamber 305, a reagent needle 306, a locking tongue unit 307, a locking unit 308, a pull hook 309, a first elastic element 310, a support partition 311, a micro switch 312, a rib 313, a guide groove 314, a guide seat 315, a sliding shaft 316, a positioning groove 317, and a guide plate 318.
[0106] First direction X, second direction Y
[0107] Left shell 3021, right shell 3022,
[0108] Base 3071, protrusion 3072, elastic part 3073, limiting protrusion 3074, initial position 3001, locking position 3002, first slide rail 3003, second slide rail 3004, first segment A, second segment B, third segment C, fourth segment D, first inflection point M, second inflection point N, bending part E, locking part E1, guide part E2, first step 3005, second step 3006, third step 3007.
[0109] Guide hole 3111, guide rail 3112, sliding groove 3113, second elastic element 3114, guide slope 3115,
[0110] Reagent container box 3011, reagent bag 3012,
[0111] Suction nozzle 3013, device body 3014, fixing structure 3015, front limiting block 3151, rear limiting block 3152, connecting block 3153, electronic tag 3154, liquid accumulation section 3155.
[0112] Card slot 3016, positioning structure 3017, panel 3018,
[0113] Base plate 3161, side plate 3162, guide rib 3163, body clamping interface 3164, guide opening 3165, positioning hole 3166, inclined surface 317. Detailed Implementation
[0114] The following specific examples illustrate the implementation of the present invention. Those skilled in the art can easily understand other advantages and effects of the present invention from the content disclosed in this specification. The present invention can also be implemented or applied through other different specific embodiments, and various details in this specification can also be modified or changed based on different viewpoints and applications without departing from the spirit of the present invention.
[0115] It should be understood that the invention can be embodied in various forms and should not be construed as being limited to the embodiments set forth herein. Rather, providing these embodiments will make the disclosure thorough and complete, and will fully convey the scope of the invention to those skilled in the art.
[0116] In a first embodiment, a sample analyzer is provided, comprising a housing 1 and a reagent interaction module 3 disposed at a reagent assembly point on the front of the housing 1. The reagent interaction module 3 includes a reagent container storage device 2, which comprises a storage chamber 302 having three accommodating spaces 304, and reagent container receiving boxes 301 arranged one-to-one with each of the accommodating spaces 304. In specific implementations, the number of accommodating spaces 304 can be appropriately increased or decreased, or the number of storage chambers 302 can be increased, depending on the specific sample testing needs.
[0117] In another embodiment, a sample analyzer is provided, including a housing 1 and a reagent interaction module 3 disposed on the front of the housing 1 at a reagent assembly point. Unlike the first embodiment, the reagent interaction module 3 in this embodiment may include three reagent container storage devices 2 arranged side-by-side. Each reagent container storage device 2 includes a storage chamber 302 with a receiving space 304 and a reagent container receiving box 301 disposed one-to-one with the receiving space 304.
[0118] The following is an extended description based on the second embodiment: Appendix Figure 1 This is a schematic diagram of the structure of a sample analyzer according to the present invention; attached. Figure 2 This is a schematic diagram of the structure of the reagent interaction module 3 of the present invention.
[0119] Please see the appendix Figure 1 As shown, a sample analyzer includes a housing 1 and a reagent interaction module 3 disposed at a reagent assembly point on the front of the housing 1. (See attached diagram.) Figure 2 and 3 As shown in Figure 4, the reagent interaction module 3 of the present invention includes three reagent container storage devices 2 connected side by side. A gap-sealing plate 4 is provided on the front of each reagent container storage device 2, connecting the reagent container storage devices 2 and covering the gaps between them. The gap-sealing plate 4 has an assembly hole 401 corresponding to each reagent container storage device 2. An electronic tag board 5 and an antenna board 6 are provided on the rear side of each reagent container storage device 2. A mounting plate 7 is fixedly provided on the bottom surface of the reagent interaction module 3.
[0120] Please see the appendix Figure 4As shown: The reagent container storage device 2 includes a reagent container housing 301 and a storage chamber 302. The reagent container housing 301 has a receiving cavity for positioning and fixing the reagent container. The reagent container has a reagent puncture part 303. The storage chamber 302 has a receiving space 304 inside, and the storage chamber 302 has an assembly port. A reagent needle 306 is fixed in the receiving space 304. The reagent container housing 301 is movably installed in the storage chamber 302, specifically in a drawer-type assembly. The storage chamber 302 has a locking position and an unlocking position. The reagent container housing 301 is inserted into the receiving space 304 from the assembly port along the first direction X, first passing through the unlocking position and then being assembled to the locking position. In the locking position, the reagent needle 306 punctures the reagent container through the reagent puncture part 303 and communicates with the reagent container. When the reagent container housing 301 is withdrawn from the receiving space 304 from the assembly port along the first direction X to the unlocking position, the reagent needle 306 separates from the reagent container. In the specific implementation process, as shown in the figure, the first direction X is the loading direction of the reagent container 301, which is also the direction in which the reagent puncture part 303 points towards the reagent needle 306, ensuring that the assembly and puncture are carried out simultaneously.
[0121] In some embodiments, such as Figure 15 As shown in Figure c, the storage chamber 302 also has a replacement position. When the reagent container holding box 301 is in the replacement position, a reagent container can be put into or taken out of the reagent container holding box 301. In the replacement position, the reagent container holding box 301 is not completely separated from the storage chamber 302. Of course, in the specific implementation process, the storage chamber 302 may not have a replacement position (not shown in the figure), which is equivalent to the reagent container holding box 301 being completely removed from the storage chamber 302. In this way, after the actual container holding box is separated from the storage chamber 302, a reagent container can be put into or taken out of the reagent container holding box 301.
[0122] For specific implementation details, please refer to the appendix. Figure 5 As shown, the storage chamber 302 is formed by fastening together a left shell 3021 and a right shell 3022, and the receiving space 304 is formed between the left shell 3021 and the right shell 3022. A motion locking chamber 305 is provided at the lower part of the receiving space 304. The assembly port is located on the front of the receiving space 304, and the reagent needle 306 is located on the back of the receiving space 304.
[0123] In some embodiments, such as Figure 5As shown, the reagent container housing 301 includes a positioning structure 3017, and a fixing structure 3015 corresponding to the positioning structure 3017 is provided on the reagent container. The fixing structure 3015 cooperates with the positioning structure 3017 to position and fix the reagent container in the housing cavity. In a specific implementation, the positioning structure 3017 is a U-shaped card interface, and the fixing structure 3015 is inserted into the U-shaped card interface and limits the fixing structure 3015 in the first direction. The housing cavity of the reagent container housing 301 has an opening for loading or unloading the reagent container in a second direction, which is perpendicular to the first direction.
[0124] In the specific implementation process, such as Figure 19 As shown, the reagent container 301 specifically includes a bottom plate 3161 on the bottom side, side plates 3162 on both sides of the bottom plate 3161, and a panel 3018 facing away from the positioning structure 3017. The reagent container 301 is designed for the reagent bag 3012. The opening is located on the top side. The positioning structure 3017 and the panel 3018 are respectively located at the front and rear ends of the bottom plate 3161. The inner surface of the bottom plate 3161 is a slope 317 where the front end is lower than the rear end. The bottom plate 3161, side plates 3162, and panel 3018 protect and isolate the rear of the reagent bag 3012. The slope 317 is designed to accumulate the reagent in the reagent bag 3012 towards the nozzle 3013, so that the reagent in the reagent bag 3012 is as little as possible and the reagent is utilized as much as possible. In specific implementation, when there are multiple cavities, adjacent cavities share a side plate 3162. At least two pairs of guide ribs 3163 are provided on the inner walls of the two side plates 3162 of the receiving cavity. Each pair of guide ribs 3163 is evenly distributed from the front end to the rear end of the receiving cavity. Each guide rib 3163 extends upward from the bottom plate 3161, and a body locking interface 3164 for positioning and securing the reagent bag 3012 is formed between each pair of guide ribs 3163. The ribs 313 are used to position and straighten the reagent bag 3012.
[0125] To prevent reagent bag 3012 from getting stuck when being inserted into the receiving cavity, such as Figure 19 As shown, a funnel-shaped guide opening 3165 is provided on the upper part of the body locking interface 3164 for guiding and positioning. The guide opening 3165 guides the reagent bag 3012 into the locking slot 3016. The body locking interface 3164 positions and straightens the lower side of the reagent bag 3012. The side plate 3162 is a wedge-shaped plate with a front end height lower than the rear end height. The lower front end height allows the upper front corner of the reagent bag 3012 to be exposed, facilitating the handling of the reagent bag 3012. In addition, the wedge-shaped plate structure facilitates the overall guiding and installation of the reagent container housing 301.
[0126] Please see the appendix Figure 14 and 15 As shown in a, 15b, and 15c: In some embodiments, the receiving space 304 is provided with guide grooves 314 for directional guidance of the reagent container receiving box 301 into or out of the receiving space 304. The guide grooves 314 are arranged in pairs and extend along the first direction X, respectively disposed on the inner walls of the left shell 3021 and the right shell 3022. The bottom of the reagent container receiving box 301 is also provided with a guide seat 315. The guide seat 315 is provided with a sliding shaft 316 for engaging with and directionally sliding with the guide grooves 314. The sliding shaft 316 is disposed near the front end of the guide seat 315. For example... Figure 15 As shown in Figure c, for the replacement position, the guide groove 314 can be designed as a closed groove, with the sliding shaft 316 confined within it. The main body of the reagent container 301 can be pulled out of the storage chamber 302, but not completely separated. Alternatively, the guide groove 314 can be designed with the assembly port side open, as shown in the figure. In this case, the sliding shaft 316 can detach from the guide groove 314, and the reagent container 301 and reagent bag 3012 can be completely pulled out of the storage chamber 302 together. Additionally, the reagent container 301 has a first marking on the side opposite to the positioning structure 3017. This first marking can be characters such as FN, FR, or FD, or it can be an indicator light.
[0127] In some embodiments, the reagent container housing 301 is located within the storage chamber 302, and is switched between a locked position and an unlocked position by pressing the reagent container housing 301. (See appendix) Figure 15 and 17As shown: To maintain the press-to-switch between the locked and unlocked positions after the reagent container 301 and the storage chamber 302 are assembled, the storage chamber 302 is also provided with a locking tongue unit 307, and the reagent container 301 is provided with a locking unit 308 that cooperates with the locking tongue unit 307. The locking tongue unit 307 provides a first elastic force to the locking unit 308. When the reagent container 301 is pressed, the locking tongue unit 307 connects to the locking unit 308 through the first elastic force, and the reagent container 301 is in the locked position. Pressing the reagent container 301 provides a force that overcomes the first elastic force, releasing the connection between the locking tongue unit 307 and the locking unit 308, and the reagent container 301 is in the unlocked position. When the reagent container 301 is pressed and pushed into the storage chamber 302, it is locked by the cooperation of the locking tongue unit 307 and the locking unit 308, and the reagent container 301 is stably connected to the storage chamber 302. When the reagent container 301 is pulled out, the first elastic force is overcome by the pulling force or the component of the pulling force, and the connection between the locking tongue unit 307 and the locking unit 308 is released, so that the reagent container 301 and the storage chamber 302 are unlocked.
[0128] In the specific implementation process, according to the specific installation space and assembly requirements, the specific setting position and structure of the locking tongue unit 307 are as follows: The locking tongue unit 307 is located inside the motion locking chamber 305, such as... Figure 5 and 6 As shown, the locking tongue unit 307 includes a base 3071, a protrusion 3072 disposed on the base 3071, and an elastic part 3073 connected to the protrusion 3072. One end of the elastic part 3073 is fixed to the protrusion 3072, and the other end extends in the first direction X. When subjected to downward pressing force, the elastic part 3073 provides an upward first elastic force. When the reagent container 301 is inserted into the locking position in the storage chamber 302, the elastic part 3073 is connected to the locking unit 308 under the action of the first elastic force; the protrusion 3072 abuts against and is positioned with the reagent container 301. It should be noted that the locking unit 308 that cooperates with the locking tongue unit 307 can be a locking hole or a positioning protrusion that directly cooperates with the elastic part 3073. The area where the elastic part 3073 cooperates with the locking hole or positioning protrusion is provided with a limiting protrusion 3074. The limiting protrusion 3074 is partially inserted into the locking hole or engaged with the positioning protrusion. The limiting protrusion 3074 has inclined surfaces 317 on both sides in the first direction X to prevent the elastic part 3073 from jamming with the locking unit 308, so as to overcome the first elastic force for assembly or disengagement.
[0129] Please see the appendix Figure 5 and 11As shown in Figures 12 and 9-1: The base 3071 is reciprocatingly slidable in the first direction X. The storage chamber 302 is provided with a hook 309 and a first elastic element 310. The tail of the hook 309 is fixed in the first direction X, and the head of the hook 309 hooks the base 3071 at its initial position 3001 or locked position 3002 along the first direction X. The first elastic element 310 provides a reset elastic force to the base 3071 in the opposite direction of the first direction X. The reagent container 301 is inserted into the storage chamber 302 and pushes the base 3071 along... The first direction X moves to the locking position, the head of the hook 309 moves from the initial position 3001 of the base 3071 to the locking position 3002 and hooks the locking position 3002. The hook 309 is balanced with the reset force of the first elastic element 310. The reagent container 301 unlocks and exits the locking position along the first direction X. The head of the hook 309 disengages from the locking position 3002 and moves to the initial position 3001 under the reset force of the first elastic element 310. The base 3071 pushes the reagent container 301 out of the locking position.
[0130] That is, the reagent container 301 is pushed into the receiving space 304, the reagent container 301 abuts against the protrusion of the base 3071 and the locking tongue unit 307 is connected and locked with the locking unit 308, and at the same time the base 3071 is pushed and moves in the first direction X against the reset elastic force of the first elastic element 310 until the reagent needle 306 pierces the reagent puncture part 303. At this time, the hook 309 hooks the locking position 3002 of the base 3071, so that the reagent container 301 is kept in the locked position; the reagent container 301 is pressed again and the hook 309 disengages from the locking position 3002 of the base 3071. The first elastic element 310 drives the base 3071 and pushes the reagent container 301 to move in the opposite direction of the first direction X until the hook 309 catches the initial position 3001 of the base 3071, causing the reagent container 301 to pop out a certain distance. Then, by pulling the reagent container 301 with external force, the locking tongue unit 307 and the locking unit 308 are released from the locking state, and the reagent container 301 is taken out from the receiving space 304, completing the extraction from the storage chamber 302. In specific implementation, the first elastic element 310 can be a tension spring.
[0131] Please see the appendix Figure 9-2As shown: In some embodiments, in order to make the switching of the head of the hook 309 between the initial position 3001 and the locked position 3002 smoother, two guide slides, namely the first slide 3003 and the second slide 3004, are provided between the initial position 3001 and the locked position 3002. The first slide 3003 and the second slide 3004 are connected end to end to form a loop. The head of the hook 309 moves from the initial position 3001 to the locked position 3002 along the first slide 3003 and is fixed at the locked position 3002. It moves from the locked position 3002 to the initial position 3001 along the second slide 3004 and is fixed at the initial position 3001.
[0132] Combined with appendix Figure 8 and 9-2 As shown: In some embodiments, along the head movement direction of the hook 309, the first slide 3003 and the second slide 3004 are sequentially divided into a first segment A, a second segment B, a third segment C, and a fourth segment D. The connection between the first segment A and the second segment B serves as a first inflection point M, used to guide the head of the hook 309 to move towards the second segment B. The second segment B and the third segment C combine to form a "V"-shaped slide. The curved portion E of the "V"-shaped slide serves as the locking position 3002. The connection between the third segment C and the fourth segment D serves as a second inflection point N, used to guide the head of the hook 309 to move towards the fourth segment D. The starting end of the first segment A and the ending end of the fourth segment D converge to form the starting position.
[0133] Please see the appendix Figure 9-2As shown: When the reagent container holder 301 is pushed in, it is pushed into the receiving space 304 along the first direction X until the locking tongue unit 307 connects with the locking unit 308. Continuing to press the reagent container holder 301 inward pushes the base 3071 towards the tail of the hook 309. The head of the hook 309 moves from the initial position 3001 along the first segment A to the first inflection point M. The pressure is released, the base 3071 slightly resets, and the head of the hook 309 then turns into the second segment B at the first inflection point M and moves along the second segment B to the curved part E of the "V"-shaped slide, i.e., the locking position 3002. The head of the hook 309 can stably hook onto the curved part E, completing the installation of the reagent container holder 301. When the reagent container holder 301 is pulled out, the reagent container holder is slightly pressed... The container 301 causes the head of the hook 309 to disengage from the bend E of the "V"-shaped slide and move along the third segment C to the second inflection point N. The pressure is released, and the base 3071 moves in the opposite direction X under the reset elastic force of the first elastic element 310. The head of the hook 309 turns into the fourth segment D at the second inflection point N and moves along the fourth segment D to the initial position 3001. At this time, the base 3071 ejects the reagent container 301 from the storage chamber 302 a certain distance, providing a point of force for external force. Under the action of external force, the reagent container 301 continues to be pulled out of the storage chamber 302. The external force overcomes the resistance of the first elastic force, causing the reagent container 301 to separate from the base 3071 and partially or completely pull the reagent container 301 out of the storage chamber 302. The distance of slightly pressing the reagent container holder 301 includes, but is not limited to, 2~5mm, and the distance of the reagent container holder 301 popping out includes, but is not limited to, 20~30mm, which can be designed according to the specific size and space of the product.
[0134] Please see the appendix Figure 9-3 and 9-4As shown: In some embodiments, from the starting end of the first segment A to the bend E, the depth of the first slide rail 3003 first decreases, then increases again at the first inflection point M; from the bend E to the ending end of the fourth segment D, the depth of the second slide rail 3004 first decreases, then increases again at the second inflection point N. In the specific implementation process, the first slide rail 3003 and the second slide rail 3004 are both opened on the bottom surface relative to the base 3071. Relative to the bottom surface of the base 3071, the position of the first segment A gradually rises from low to high along the travel direction of the hook 309 head until the first inflection point M; the position of the second segment B gradually decreases from high to low along the travel direction relative to the bottom surface. The highest point of the first segment A is higher than the highest point of the second segment B, forming a first step 3005 to guide the second segment B, so as to prevent the hook 309 head from returning to the starting end along the first segment A; the position of the third segment C gradually rises from low to low along the travel direction relative to the bottom surface until the second inflection point N; the position of the fourth segment D gradually decreases from high to low along the travel direction relative to the bottom surface. The highest point of the third segment C is higher than the highest point of the fourth segment D, forming a second step 3006 to guide the fourth segment D, so as to prevent the hook 309 head from returning to the curved part E of the "V"-shaped slide along the third segment C. The area where the fourth segment D connects with the first segment A forms a third step 3007 where the fourth segment D is higher than the first segment A. In addition, during the movement, the head of the hook 309 abuts against the bottom of the slide. As the head of the hook 309 moves from the starting end of the first section A to the first inflection point M, the depth of the slide gradually decreases, and the pressure on the hook 309 increases. After passing the first inflection point M, the depth increases, and the reaction force of the head of the hook 309 pushes the head of the hook 309 along the second section B to the curved part E of the deeper "V"-shaped slide. The same applies to the third section C and the fourth section D, forcing the head of the hook 309 to move along a single route, that is, sequentially along the first section A to the second section B to the third section C and then to the fourth section D.
[0135] Please see the appendix Figure 8 As shown: In some embodiments, to further ensure the uniqueness of the travel path of the hook 309 head, the curved portion E of the "V"-shaped slide includes a locking portion E1 with a concave sidewall and a guide portion E2 with a protruding sidewall. When the hook 309 is in the locking position 3002, the head of the hook 309 hooks the locking portion E1, and the head of the hook 309 disengages from the locking portion E1. The guide portion E2 guides the head of the hook 309 to deflect towards the third segment C. In other words, the centerline of the main body of the hook 309 is biased towards the third segment C, and the top of the guide portion E2 is biased towards the second segment B, ensuring that when the reagent container 301 is pressed, the head of the hook 309 can move towards the third segment C immediately under the action of the guide portion E2.
[0136] Please see the appendix Figure 5 and 7As shown: In some embodiments, a support partition 3113 for supporting the reagent container 301 is provided between the motion locking chamber 305 and the receiving space 304. The support partition 3113 separates the motion locking chamber 305, providing support for the reagent container 301. Furthermore, the support partition 3113 also acts as a guide, facilitating the smooth insertion of the reagent container 301. The support partition 311 has a guide hole 31113 extending along a first direction X. The base 3071 engages with the guide hole 3111 via the protrusion 3072 and slides back and forth along the first direction X. This provides the base 3071 with an installation position, sliding space, and sliding direction, while also limiting the maximum stroke of the base 3071's reciprocating slide through the guide hole 3111, thereby controlling the maximum distance the reagent container 301 can eject.
[0137] Please see the appendix Figure 12 and 13 As shown: In some embodiments, the lower side of the support partition 311 is provided with a guide rail 3112 extending along the first direction X, such as... Figure 6 As shown, the base 3071 is provided with a directional sliding groove 311333, and the base 3071 slides in cooperation with the guide rail 3112 through the directional sliding groove 3113. The cooperation between the sliding groove 3113 and the guide rail 3112 can further improve the stability of the reciprocating sliding of the base 3071.
[0138] Please see the appendix Figure 5 and 12 As shown: In some embodiments, a second elastic element 3114 is provided below the base 3071. The second elastic element 3114 provides a second elastic force to the hook 309, which pushes the hook 309 against the base 3071 to prevent the hook 309 from falling out of the slide of the base 3071. In specific implementation, the second elastic element 3114 adopts a spring sheet structure, with one end of the spring sheet fixed and the main body of the spring sheet abutting against the main body of the hook 309 to provide an upward elastic force.
[0139] Please see the appendix Figure 10 As shown: In some embodiments, the support partition 311 extends to the assembly port, and the support partition 311 is provided with a guide slope 3115 at the assembly port. The front end of the reagent container holder 301 is inclined at a certain angle along the guide slope 3115 to facilitate the placement and removal of the reagent bag 3012. (See attached diagram) Figure 15 As shown in a, 15b and 15c, the dynamic process of the reagent container 301 being pulled out of the storage chamber 302 can be seen. At the guide slope 3115, the reagent container 301 is tilted relative to the storage chamber 302, making room for the reagent bag 3012 to be placed or removed.
[0140] Please see the appendix Figure 5 and 7 As shown: In some embodiments, the motion locking chamber 305 is provided with a micro switch 312 for determining whether the reagent container 301 is in the locking position. When the reagent container 301 is pushed into the locking position, the micro switch 312 is triggered, generating an electrical signal, which can be displayed by an indicator light or other means to remind the reagent container 301 that it is in place.
[0141] Please see the appendix Figure 5 and 10 As shown: In some embodiments, the inner wall of the accommodating space 304 is provided with multiple ribs 313, which extend along a first direction X, and the multiple ribs 313 are evenly and parallelly distributed in a direction perpendicular to the first direction X. The two sides of the reagent container accommodating box 301 are in contact with the ribs 313, reducing the sliding friction of the reagent container accommodating box 301.
[0142] Please refer to Figures 9 and 20: In some embodiments, the locking unit 308 includes a locking hole provided on the guide seat 315. The locking hole can cooperate with the elastic portion 3073 of the latch unit 307. Figure 20 As shown, the lower surface of the guide seat 315 is also provided with a positioning groove 317, which is mainly used for positioning and cooperating with the protrusion 3072 of the locking tongue unit 307 when the reagent container 301 is replaced and installed. The guide groove 314 extends from the front end of the guide seat 315 to the rear.
[0143] The present invention provides a reagent container storage device 2 for use as a container for storing fluorescent reagents.
[0144] This invention provides a reagent container, which can be used to hold latex reagents, hemolysis reagents, dilution reagents, and fluorescent reagents. The reagent container includes a reagent bottle or reagent bag 3012. The following description uses a reagent bag 3012 as an example. Please refer to the appendix. Figure 17 and 18As shown: The reagent bag 3012 includes a suction nozzle 3013 and a body 3014. The suction nozzle 3013 is arranged along the first direction X. The reagent puncture part 303 is provided on the suction nozzle 3013. The neck of the suction nozzle 3013 is provided with the fixing structure 3015. When the reagent bag 3012 is assembled with the reagent container box 301 along the second direction Y, the fixing structure 3015 of the suction nozzle 3013 is easily placed into the positioning structure 3017 along the second direction Y. The positioning structure 3017 limits the suction nozzle 3013 in the first direction X. Therefore, whether the reagent container box 301 is subjected to installation force or the suction nozzle 3013 is subjected to puncture force, it will not affect the stable assembly of the suction nozzle 3013 and the positioning structure 3017 in the first direction X.
[0145] Please see the appendix Figure 18 and 19 As shown: In some embodiments, the fixing structure 3015 includes a front limiting block 3151, a rear limiting block 3152, and a connecting block 3153 connecting the front limiting block 3151 and the rear limiting block 3152. The front limiting block 3151, the rear limiting block 3152, and the connecting block 3153 are combined to form an I-shape. The connecting block 3153 is inserted into the U-shaped card interface. The front limiting block 3151 and the rear limiting block 3152 clamp the two sides of the U-shaped card interface and limit it in the first direction X. Based on the perpendicularity of the first direction X and the second direction Y, when the reagent is replaced, the fixing structure 3015 can be easily inserted into the U-shaped card interface along the second direction Y without causing excessive compression to the reagent bag 3012. Meanwhile, the U-shaped card interface can also limit the fixing structure 3015 in the first direction X, which can stabilize the nozzle 3013. When the reagent container 301 is installed and subjected to puncture force, it can remain stable in the first direction X and will not move in the second direction Y. In specific implementation, the front limiting block 3151 is equipped with an electronic tag 3154 on the side facing the nozzle 3013 for identification, anti-counterfeiting, tracking, etc.
[0146] Other examples Figure 17 and 18 As shown, the suction nozzle 3013 is positioned near the base plate 3161, and the body 3014 has a liquid collection section 3155, which is positioned near the suction nozzle 3013. The base plate 3161 has a positioning hole 3166 for positioning the liquid collection section 3155 of the reagent bag 3012. After the reagent bag 3012 is assembled with the reagent container 301, both the suction nozzle 3013 and the liquid collection section 3155 are close to the base plate 3161. This allows as much reagent as possible to accumulate in the liquid collection section 3155, facilitating extraction by the puncture needle and reducing reagent waste.
[0147] Therefore, in the reagent container holder 301, the reagent bag 3012 is inserted into the receiving cavity of the reagent container holder 301 along the second direction Y, and is positioned and aligned by the guide ribs 3163 to maintain the uniformity of reagent distribution within the reagent bag 3012. The positioning structure 3017 cooperates with the fixing structure 3015 of the nozzle 3013 for installation, taking into account the convenience of assembling and disassembling the reagent bag 3012 and the reagent container holder 301 in the second direction Y, and also ensuring the stability of the reagent bag 3012 assembly in the first direction X. The wedge-shaped design of the side plate 3162 and the setting of the guide seat 315 make the guidance and positioning of the reagent container holder 301 easier and more accurate during replacement. The entire replacement process only requires contact with the reagent container holder 301. The rigid reagent container holder 301 not only plays a role in isolation, but also provides more stable stress distribution compared to the soft reagent bag 3012, making assembly more convenient and safer.
[0148] Please see the appendix Figure 7 and 10 As shown: In some embodiments, the receiving space 304 is provided with a guide plate 318 to guide the reagent puncture portion 303 of the reagent bag 3012. The guide plate 318 can guide the suction nozzle 3013 of the reagent bag 3012 to prevent the reagent needle 306 from being inserted off-center.
[0149] In addition, in some embodiments, the reagent container further includes a refrigeration module for controlling the reagents inside the reagent container within a preset temperature range.
[0150] This invention provides a sample analysis system, including a detection subsystem, a reagent container storage device 2, and a reagent management subsystem. The system includes a reaction chamber, which serves as the reaction site for the sample and reagents. The reagent container storage device 2 includes a storage chamber 302 and a reagent container receiving box 301. The storage chamber 302 has at least two receiving spaces 304, and the reagent container receiving box 301 is configured one-to-one with each receiving space 304. The reagent container receiving box 301 and the storage chamber 302 adopt the structure described in any of the above embodiments. The reagent management subsystem is used to control the supply of reagents and the loading and / or replacement of reagent containers.
[0151] In some embodiments, the sample analysis system further includes an information reading module for reading information from the reagent container 301.
[0152] In one embodiment, the information reading module includes an information reading unit capable of simultaneously reading information from multiple reagent container holders 301; the reagent management subsystem is communicatively connected to the information reading module. The information reading unit includes multiple reading areas, capable of simultaneously reading and displaying multiple RFID tags. When the received "reagent loading and / or reagent replacement instruction" targets only some of the reagent container holders 301, the reagent management subsystem controls the information reading unit to activate only the information reading area of the reagent container holder 301 corresponding to the instruction. For example, if there are three RFID tags: FN, FR, and FD, and only FN has a replacement instruction while FR and FD are normal, the reagent management subsystem controls the information reading unit to activate only the information reading area of the reagent container holder 301 corresponding to the FN tag. Additionally, it will display the reading information of the reagent container holder 301 corresponding to the instruction.
[0153] In another embodiment, the information reading module includes multiple information reading units, each of which is configured one-to-one with the reagent container 301, and the reagent management subsystem is communicatively connected to the information reading module.
[0154] Based on the two aforementioned implementation methods, when the sample analysis system receives a reagent loading and / or reagent replacement instruction, the reagent management subsystem controls the information reading unit to initiate information reading. The reagent management subsystem determines the information read by the information reading unit based on factors including the presence or absence of a label, whether the reagent is within its expiration date, and one or more reagent types.
[0155] In some embodiments, the reagent management subsystem is further configured to perform a first judgment on the information read by the information reading unit: if the first judgment of the read information is yes, a normal signal is output; if the first judgment of the read information is no, an alarm signal is output. Based on the first judgment, if the first judgment is yes, a second judgment is also included:
[0156] If the second judgment is correct, a normal signal is output and the read information is stored in the sample analysis system. In specific implementation, a confirmation window is also displayed when a normal signal is output. After receiving the confirmation instruction, the information read by the information reading unit is stored in the sample analysis system and a success signal is output. If the second judgment is incorrect, an alarm signal is output.
[0157] In some embodiments, the reagent management subsystem is further configured to judge and store the information read by the information reading unit;
[0158] If the read information is deemed satisfactory, a normal signal is output and the read information is stored in the sample analysis system. In specific implementation, a confirmation message is also displayed when a normal signal is output. After receiving the confirmation instruction, the information read by the information reading unit is stored in the sample analysis system and a success signal is output.
[0159] If the read information is deemed invalid, an alarm signal is output.
[0160] Based on the two implementation methods described above, in some embodiments, when the sample analysis system receives instructions or signals indicating successful reagent loading, reagent anomaly elimination, and / or successful reagent replacement, the reagent management subsystem controls the information reading unit to close the information reading function.
[0161] Based on the two implementation methods described above, in some embodiments, when the sample analysis system receives instructions for reagent loading, reagent malfunction, and / or reagent replacement, the reagent management subsystem activates the reagent operation interface.
[0162] Based on the two implementation methods described above, in some embodiments, when the sample analysis system receives instructions or signals indicating successful reagent loading, reagent anomaly elimination, and / or successful reagent replacement, the reagent management subsystem activates and closes the reagent operation interface.
[0163] Based on the aforementioned system, the methods for reagent loading and replacement can be specifically as follows:
[0164] Figure 21 A flowchart illustrating the steps of a fluorescent dye reagent interaction method in a sample analyzer, as shown in an exemplary embodiment of this application, is as follows: Figure 21 As shown, the detailed steps of a reagent loading method in a sample analyzer are as follows:
[0165] Step 1: When powering on for the first time and actively loading reagents, actively trigger the reagent scanning interaction command on the reagent management interface, and then load the reagent with electronic tag 3154 into the analyzer. The specific operation is as follows: Press the button to pop out the reagent container 301, put the reagent bag 3012 into the reagent container 301, and push the reagent bag 3012 and the reagent container 301 back into the analyzer together. The analyzer will automatically position and lock, completing the reagent loading.
[0166] Step 2: Receive and respond to the reagent scanning interaction command issued by the reagent management interface. Perform the first scan and identification of the reagent's electronic tag 3154.
[0167] If the first scan fails, the reagent management interface will display a reminder to reload the reagent. After reloading the reagent, the electronic tag 3154 will be scanned again. If the electronic tag 3154 fails to be scanned, it will be determined that the electronic tag 3154 is damaged or has other problems, and the reagent loading will be terminated.
[0168] If the first scan is successful, it confirms that the reagent is initially assembled. Then, the electronic tag 3154 of the reagent is scanned a second time. The interval between the second scan and the first scan can be 1 second to confirm whether the reagent is stably assembled.
[0169] If the second scan fails to identify the reagent, a reminder will be displayed on the reagent management interface to reload the reagent. After reloading the reagent, the electronic tag 3154 will be identified again. If the identification of electronic tag 3154 fails, it will be determined that electronic tag 3154 is damaged or has other problems, and the reagent loading will be terminated.
[0170] If the second scan is successful, it confirms that the reagent is stably loaded and obtains the number of electronic tags 3154. When the number of electronic tags 3154 is 1, the information of electronic tag 3154 is read directly. When the number of electronic tags 3154 is greater than 1, the information of electronic tags 3154 is read sequentially.
[0171] Step 3: Process the information from the read electronic tag 3154 to generate reagent information, including reagent type and expiration date. Other reagent information, such as remaining reagent quantity, can also be added. The hematology analyzer includes three types of fluorescent dyes: FR, FD, and FN, arranged in a specific order.
[0172] Step 4: Identify and determine the types of reagents loaded in a specific location, and simultaneously or sequentially identify and determine the expiration dates of the reagents.
[0173] If the reagent type is identified as normal, the reagent information is generated. If the reagent type is identified as abnormal, an alarm is issued and / or the reason for the abnormal reagent type is displayed on the reagent management interface, and the current reagent loading is terminated.
[0174] If the reagent is identified as being within its expiration date, the reagent information is generated. If the reagent is identified as being outside its expiration date, the reagent management interface displays a reminder that the reagent is not within its expiration date and ends the reagent loading process.
[0175] If the reagent type and its corresponding expiration date are both normal, the reagent information will be displayed as checkboxes in the reagent interaction interface.
[0176] Step 5: Select the displayed reagent types and expiration dates from the checkboxes to trigger the "Load Reagent" interaction request. "Load Reagent" refers to entering new reagent information and replacing the original reagent information to complete the update. The system receives and responds to the "Load Reagent" interaction request by entering the new reagent information and replacing the original reagent information.
[0177] If the reagent information loading and updating fails, the reagent interface will display "Loading error" and terminate the current reagent loading process.
[0178] If the reagent information is loaded and updated without any issues, and a message indicating successful loading is displayed via sound and / or the reagent interaction interface, then close the 3154 electronic tag scan to complete the reagent loading process.
[0179] Figure 22 A flowchart illustrating the steps of a reagent replacement method in a sample analyzer, as shown in an exemplary embodiment of this application, is as follows: Figure 22 As shown, a reagent replacement method in a sample analyzer includes at least two types of fluorescent dye reagents. Specifically, the fluorescent dye reagents in the sample analyzer include three types: FR, FD, and FN. Each of the three reagents (FR, FD, and FN) is individually labeled with an electronic tag 3154. The interaction method steps are as follows:
[0180] Step 1: Obtain reagent failure information and display it on the reagent management interface. The reagent failure information includes any reagent not within its expiration date, any reagent being unavailable, or any reagent needing to be replaced.
[0181] Step 2: Based on the reagent fault information, click the command to clear the "Reagent Fault Information" in the reagent management interface, and determine whether there is a "Reagent Out" fault. "Reagent Out" means that the reagent balance is insufficient.
[0182] If a "reagent unavailable" error occurs, replace the reagent with one carrying the electronic tag 3154. The specific replacement procedure is as follows: Press the button to eject the reagent container 301. Place the reagent bag 3012 into the reagent container 301. Push the reagent bag 3012 and reagent container 301 back into the analyzer together. The analyzer will automatically position and lock, completing the reagent replacement. The reagent carrying the electronic tag 3154 includes reagent bottles, reagent bags 3012, or other reagent storage devices. After the reagent loading is complete, the electronic tag 3154 scanning will automatically begin.
[0183] If there is no "reagent not found" fault, replace with reagents other than FR, FD, and FN.
[0184] Step 3: Scan and identify electronic tag 3154.
[0185] If identification of electronic tag 3154 fails, the reagent management interface will display a reminder to reload the reagent. After reloading the reagent, identify electronic tag 3154 again. If identification of electronic tag 3154 fails again, it will be determined that the reagent is not loaded, electronic tag 3154 is damaged or there is another problem, and the reagent replacement will end.
[0186] If electronic tag 3154 is successfully identified, the number of electronic tags 3154 obtained is at least 1;
[0187] Step 4: If the number of electronic tags 3154 is 1, the information of electronic tag 3154 is directly read and converted into reagent information. If the number of electronic tags 3154 is greater than 1, the information of electronic tags 3154 is sequentially verified and read to convert into reagent information. The reagent information includes reagent type and reagent expiration date.
[0188] Step 5: During the reagent information generation process, the reagent type and expiration date are checked one by one:
[0189] a. Identify and determine the type of reagent loaded at a specific location. If the reagent type is identified as normal, generate the reagent information. If the reagent type is identified as abnormal, issue an alarm and / or display the reason for the abnormal reagent type on the reagent management interface, and end the current reagent replacement.
[0190] b. Identify and determine whether the reagent is within its expiration date. If the reagent is within its expiration date, generate the reagent information. If the reagent is not within its expiration date, the reagent management interface will display a reminder that the reagent is not within its expiration date and end the reagent replacement.
[0191] Step 6: Display the obtained reagent information in the reagent management interface.
[0192] Step 7: Confirm that the obtained reagent information is correct. The reagent management interface will display a "Clear Fault" interactive request. Click "Clear Fault" to load and update the reagent information. Determine if it is successful. If successful, close the 3154 electronic tag scan and complete the reagent replacement. If it fails, the reagent management interface will display "Loading Error" and end this reagent replacement.
[0193] Figure 23 A flowchart illustrating the steps of a reagent replacement method in a sample analyzer, as shown in an exemplary embodiment of this application, is as follows: Figure 23As shown, a reagent replacement method in a sample analyzer includes at least two types of fluorescent dye reagents. Specifically, the sample analyzer uses three types of fluorescent dye reagents: FR, FD, and FN. Each of the FR, FD, and FN reagents is individually labeled with an electronic tag 3154. The sample analyzer has a trigger switch corresponding to each type of fluorescent dye reagent. The electronic tag 3154 responds to the opening and closing signals of the trigger switches in a one-to-one scan. The interaction method steps are as follows:
[0194] Step 1: Obtain reagent failure information and display it on the reagent management interface. The reagent failure information includes any reagent not within its expiration date, any reagent being unavailable, or any reagent needing to be replaced.
[0195] Step 2: Based on the reagent fault information, click the command to clear the "Reagent Fault Information" in the reagent management interface, and determine whether there is a "Reagent Out" fault. "Reagent Out" means that the reagent balance is insufficient.
[0196] If a "reagent not found" fault occurs, replace the reagent carrying the electronic tag 3154. Reagents carrying the electronic tag 3154 include reagent bottles, reagent bags 3012, or other reagent storage devices. The specific replacement procedure is as follows: Press the button to eject the reagent container 301. Place the reagent bag 3012 into the reagent container 301. Push the reagent bag 3012 and reagent container 301 back into the analyzer together. The analyzer will automatically position and lock. If the trigger switch is not activated, it indicates that the reagent is not properly loaded or has not been replaced, and the reagent can be reloaded. If the trigger switch is activated, the reagent loading is complete, and the scanning of the electronic tag 3154 will automatically begin. The electronic tag 3154 corresponding to the reagent whose trigger switch is activated will be scanned.
[0197] Step 3: Scan and identify electronic tag 3154.
[0198] If identification of electronic tag 3154 fails, the reagent management interface will display a reminder to reload the reagent. After reloading the reagent, identify electronic tag 3154 again. If identification of electronic tag 3154 fails again, it will be determined that the reagent is not loaded, electronic tag 3154 is damaged or there is another problem, and the reagent replacement will end.
[0199] If electronic tag 3154 is successfully identified, the number of electronic tags 3154 obtained is at least 1;
[0200] Step 4: If the number of electronic tags 3154 is 1, the information of electronic tag 3154 is directly read and converted into reagent information. If the number of electronic tags 3154 is greater than 1, the information of electronic tags 3154 is sequentially verified and read to convert into reagent information. The reagent information includes reagent type and reagent expiration date.
[0201] Step 5: During the reagent information generation process, the reagent type, expiration date, and batch number are checked one by one:
[0202] a. Identify and determine the type of reagent loaded at a specific location. If the reagent type is identified as normal, generate the reagent information. If the reagent type is identified as abnormal, issue an alarm and / or display the reason for the abnormal reagent type on the reagent management interface, such as "XX reagent is placed in the wrong location" or "XX reagent type is incorrect", and end the current reagent replacement.
[0203] b. Identify and determine whether the reagent is within its expiration date. If the reagent is within its expiration date, generate the reagent information. If the reagent is not within its expiration date, the reagent management interface will display a reminder that the reagent is not within its expiration date and end the reagent replacement.
[0204] c. Identify and determine whether the reagents of the same type belong to the same batch number. If the reagents are identified as belonging to the same batch number, generate the reagent information, load and update the reagent information directly, and display a reminder on the reagent management interface that the reagent replacement was successful. If the reagents are identified as belonging to different batch numbers, generate the reagent information and continue to the following steps.
[0205] Step 6: Display the acquired reagent information in a pop-up window in the reagent management interface, and only refresh and display the reagent information generated by the reagent that was changed in the current time.
[0206] Step 7: Confirm that the obtained reagent information is correct. When actively replacing reagents, the reagent management interface will display a "Replace Reagent" interaction request. When passively replacing reagents due to reagent malfunction, the reagent management interface will display a "Clear Fault" interaction request. Click the interaction request "Replace Reagent" or "Clear Fault" to load and update the reagent information. Determine if successful. If successful, a notification will be displayed via sound and / or the interface will indicate successful reagent loading. The scanning of electronic tag 3154 will be closed, or the electronic tag 3154 will be reversed / rewritten, completing the reagent replacement. If it fails, the reagent management interface will display "Loading Error," ending this reagent replacement.
[0207] The above embodiments are merely illustrative of the principles and effects of the present invention and are not intended to limit the invention. Any person skilled in the art can modify or alter the above embodiments without departing from the spirit and scope of the present invention. Therefore, all equivalent modifications or alterations made by those skilled in the art without departing from the spirit and technical concept disclosed in the present invention should still be covered by the claims of the present invention.
Claims
1. A reagent container storage device, characterized in that, include: A reagent container holder has a cavity for accommodating a reagent container; a storage chamber has at least one accommodating space inside, and an assembly opening in the storage chamber, within which a reagent needle is fixed; the reagent container holder is movably installed in the storage chamber and extends into the accommodating space along a first direction; the storage chamber has a locking position and an unlocking position; when the reagent container holder is in the locking position, the reagent needle is in communication with the reagent container; when the reagent container holder is in the unlocking position, the reagent needle is separated from the reagent container; The reagent container is located in the storage chamber, and the reagent container is switched between the locked and unlocked positions by pressing the reagent container. The storage chamber is also equipped with a locking tongue unit, and the reagent container is equipped with a locking unit that cooperates with the locking tongue unit. The locking tongue unit provides a first elastic force to the locking unit. When the reagent container is pressed, the locking tongue unit connects to the locking unit through the first elastic force, and the reagent container is in the locked position. Pressing the reagent container provides a force that overcomes the first elastic force, releasing the connection between the locking tongue unit and the locking unit, and the reagent container is in the unlocked position. Below the accommodating space is a movable locking chamber, and the locking tongue unit is disposed within the movable locking chamber. The locking tongue unit includes a base, a protrusion on the base, and an elastic part connected to the protrusion. One end of the elastic part is fixed to the protrusion, and the other end extends in a first direction. When subjected to a downward compressive force, the elastic part provides an upward first elastic force. When the reagent container is inserted into the locking position in the storage chamber, the elastic part connects to the locking unit under the action of the first elastic force; the protrusion abuts against and is positioned with the reagent container. The base is slidably oriented in the first direction. The storage chamber is provided with a hook and a first elastic element. The tail of the hook is fixed in the first direction, and the head of the hook hooks onto the base in the initial or locked position along the first direction. The first elastic element provides a reset force to the base in the opposite direction of the first direction. The reagent container is inserted into the storage chamber and pushes the base to move to the locked position along the first direction. The head of the hook moves from the initial position of the base to the locked position and hooks onto the locked position. The reset force of the hook and the first elastic element are balanced. The reagent container unlocks and exits the locked position along the first direction. The head of the hook disengages from the locked position and moves back to the initial position under the reset force of the first elastic element. The base pushes the reagent container out of the locked position.
2. The reagent container storage apparatus according to claim 1, characterized by: The storage chamber also has a replacement position, whereby the reagent container can be loaded or unloaded when the reagent container is located in the replacement position.
3. The reagent container storage device according to claim 1, characterized in that: The reagent container includes a positioning structure, and a fixing structure is provided on the reagent container corresponding to the positioning structure. The fixing structure cooperates with the positioning structure to position and fix the reagent container in the receiving cavity.
4. The reagent container storage device according to claim 3, characterized in that: The positioning structure is a U-shaped card interface, and the fixing structure is inserted into the U-shaped card interface and limits the fixing structure in the first direction.
5. The reagent container storage device according to claim 4, characterized in that: The reagent container housing has an opening for loading or unloading the reagent container in a second direction, which is perpendicular to the first direction.
6. The reagent container storage device according to claim 4, characterized in that: The accommodating space is provided with a guide groove for guiding the reagent container container into or out of the accommodating space. The guide groove extends along the first direction. The bottom of the reagent container container is also provided with a guide seat. The guide seat is provided with a sliding shaft for cooperating with the guide groove and sliding in a directional manner. The sliding shaft is located near the front end of the guide seat.
7. The reagent container storage device according to claim 4, characterized in that: The reagent container is marked with a first mark on the side opposite to the positioning structure; the reagent container also includes a refrigeration module for controlling the reagents in the reagent container within a preset temperature range.
8. The reagent container storage device according to claim 1, characterized in that: The storage chamber includes at least three storage spaces, and each storage space corresponds to the installation of one reagent container box.
9. The reagent container storage device according to claim 1, characterized in that: The initial position and the locked position are connected by a first slide and a second slide, which are connected end to end. The head of the hook moves from the initial position to the locked position along the first slide and is fixed at a fixed point in the locked position. It also moves from the locked position to the initial position along the second slide and is fixed at a fixed point in the initial position.
10. The reagent container storage device according to claim 9, characterized in that: Along the direction of movement of the hook head, the first and second slides are sequentially divided into a first segment, a second segment, a third segment, and a fourth segment. The connection between the first and second segments serves as the first inflection point, used to guide the hook head to move towards the second segment. The second and third segments combine to form a "V"-shaped slide. The curved part of the "V"-shaped slide serves as the locking position. The connection between the third and fourth segments serves as the second inflection point, used to guide the hook head to move towards the fourth segment. The starting end of the first segment and the ending end of the fourth segment converge to form the starting position.
11. The reagent container storage device according to claim 10, characterized in that: From the starting end of the first segment to the bend, the depth of the first slide rail first decreases, and then increases again at the first inflection point; from the bend to the ending end of the fourth segment, the depth of the second slide rail first decreases, and then increases again at the second inflection point.
12. The reagent container storage device according to claim 10, characterized in that: The curved part of the "V"-shaped slide includes a locking part with a concave side wall and a guide part with a protruding side wall. When the hook is in the locking position, the head of the hook hooks onto the locking part. When the head of the hook retracts from the locking part, the guide part guides the head of the hook to shift to the third segment.
13. The reagent container storage device according to claim 1, characterized in that: A support partition for supporting the reagent container is provided between the motion locking chamber and the accommodating space. The support partition has a guide hole extending in a first direction. The base is configured to reciprocate in the first direction by engaging with the guide hole through the protrusion.
14. The reagent container storage device according to claim 13, characterized in that: The lower side of the support partition is provided with a guide rail extending in a first direction, and the base is provided with a directional sliding groove, through which the base slides in cooperation with the guide rail.
15. The reagent container storage device according to claim 13, characterized in that: A second elastic element is provided below the base, and the second elastic element provides a second elastic force to the hook, which pushes the hook toward the base.
16. The reagent container storage device according to claim 13, characterized in that: The support partition extends to the assembly port, and the support partition is provided with a guide slope at the assembly port.
17. The reagent container storage device according to claim 1, characterized in that: The motion locking chamber is equipped with a micro switch for determining whether the reagent container holder is in the locking position.
18. The reagent container storage device according to claim 1, characterized in that: The inner wall of the accommodating space is provided with multiple ribs, which extend along a first direction and are evenly and parallelly distributed in a direction perpendicular to the first direction.
19. The reagent container storage device according to claim 6, characterized in that: The locking unit includes a locking hole disposed on the guide seat.
20. Use of a reagent container storage device as described in any one of claims 1 to 19, characterized in that: A storage device that serves as a container for storing fluorescent reagents.
21. A reagent interaction module, characterized in that: It includes multiple reagent container storage devices connected side by side, wherein the reagent container storage device is the reagent container storage device according to any one of claims 1 to 19.
22. The reagent interaction module according to claim 21, characterized in that: The reagent container storage device has a gap-covering plate on the surface where the assembly port is located. The gap-covering plate connects the reagent container storage devices and covers the gaps between the reagent container storage devices. The gap-covering plate has an assembly hole corresponding to the assembly port of each reagent container storage device.
23. The reagent interaction module according to claim 22, characterized in that: An electronic tag board and an antenna board are provided on the rear side away from the assembly port of the reagent container storage device.
24. The reagent interaction module according to claim 22, characterized in that: The bottom surface of the reagent interaction module is fixedly equipped with a mounting plate.
25. A sample analyzer, characterized in that, Includes the reagent interaction module as described in any one of claims 21 to 24.
26. A sample analysis system, characterized in that, include: A detection subsystem, comprising a reaction tank; a reagent container storage device, wherein the reagent container storage device is the reagent container storage device according to any one of claims 1 to 19, wherein the storage tank has at least two accommodating spaces, and the reagent container accommodating box is provided one-to-one with the accommodating space; and a reagent management subsystem for controlling the supply of reagents and the loading and / or replacement of reagent containers.
27. The sample analysis system according to claim 26, characterized in that: The sample analysis system also includes an information reading module for reading information about reagent container holders.
28. The sample analysis system according to claim 27, characterized in that: The information reading module includes an information reading unit that can simultaneously read information from multiple reagent container boxes; the reagent management subsystem is communicatively connected to the information reading module.
29. The sample analysis system according to claim 27, characterized in that: The information reading module includes multiple information reading units, each of which is configured one-to-one with the reagent container. The reagent management subsystem is communicatively connected to the information reading module.
30. The sample analysis system according to claim 28 or 29, characterized in that: When receiving a reagent loading and / or reagent replacement instruction, the reagent management subsystem controls the information reading unit to start information reading.
31. The sample analysis system according to claim 30, characterized in that: The reagent management subsystem is also used to judge the information read by the information reading unit; if the information read is judged to be correct, a normal signal is output; if the information read is judged to be incorrect, an alarm signal is output.
32. The sample analysis system according to claim 31, characterized in that: The reagent management subsystem determines the information read by the information reading unit based on factors including the presence or absence of a label, whether the reagent is within its expiration period, and one or more reagent types.
33. The sample analysis system according to claim 31, characterized in that: The reagent management subsystem's judgment of the information read by the information reading unit includes a first judgment. If the first judgment is correct, a second judgment is also included. If the second judgment is correct, a normal signal is output and the read information is stored in the sample analysis system. If the second judgment is negative, an alarm signal is output.
34. The sample analysis system according to claim 33, characterized in that: If the second judgment is correct, a normal signal is output and a confirmation message is displayed; upon receiving the confirmation instruction, the information read by the information reading unit is stored in the sample analysis system and a success signal is output.
35. The sample analysis system according to claim 30, characterized in that: The reagent management subsystem is also used to judge and store the information read by the information reading unit; when the information read is judged to be correct, a normal signal is output and the information read is stored in the sample analysis system; when the information read is judged to be incorrect, an alarm signal is output.
36. The sample analysis system according to claim 35, characterized in that: If the read information is deemed satisfactory, a normal signal is output and a confirmation message is displayed; upon receiving the confirmation instruction, the read information is stored in the sample analysis system and a success signal is output.
37. The sample analysis system according to claim 30, characterized in that: Upon receiving a confirmation instruction for reagent loading and / or reagent replacement, the reagent management subsystem controls the reagent container to switch from the locked position to the unlocked position.
38. The sample analysis system according to claim 30, characterized in that: When the reagent management subsystem receives an instruction or signal indicating successful reagent loading, reagent malfunction elimination, and / or successful reagent replacement, it controls the information reading unit to close the information reading function.
39. The sample analysis system according to claim 30, characterized in that: When a reagent loading, reagent malfunction, or reagent replacement instruction is received, the reagent management subsystem activates the reagent operation interface.
40. The sample analysis system according to claim 30, characterized in that: When the reagent management subsystem receives an instruction or signal indicating successful reagent loading, elimination of reagent malfunction, and / or successful reagent replacement, it activates and deactivates the reagent operation interface.
41. The sample analysis system according to claim 28, characterized in that: The information reading unit includes multiple reading areas, which can read and display multiple RFID tags simultaneously. When the received "reagent loading and / or reagent replacement instruction" is for some of the reagent container boxes, the reagent management subsystem controls the information reading unit to only activate the information reading area of the reagent container box corresponding to the instruction.
42. The sample analysis system according to claim 41, characterized in that: The reagent management subsystem controls the information reading unit to only activate the information reading area of the reagent container corresponding to the instruction, and only displays the reading information of the reagent container corresponding to the instruction.