A whitening and anti-aging raw material and its preparation method and application

Abstract

The invention discloses a whitening and anti-aging raw material, which comprises, according to mass ratio: 6-15 grams of liquorice extract, 3-8 grams of arbutin, 0.5-5 grams of adenosine, 2-10 grams of collagen, 0.5-5 grams of coenzyme Q10, 1-6 grams of magnesium vitamin C phosphate, 0.5-5 grams of green tea polyphenols, 30-60 ml of fermentation liquid, 50-100 grams of nanocarrier, 80-200 grams of purified water, 800-1200 grams of cosmetic matrix and 1-5 grams of zinc oxide. The liquorice extract and arbutin are prepared by cleaning the raw materials. The material powder is mixed with solvent water, and then heated to 100-120°C, and then filtered, concentrated, purified and dried to finally obtain the corresponding extract. The present invention can effectively reduce melanin, brighten skin tone and whiten skin through the joint action of licorice extract, arbutin and magnesium ascorbyl phosphate; can provide excellent moisturizing effect through sodium hyaluronate and fermentation liquid, and maintain the moisture and elasticity of the skin; can reduce fine lines and wrinkles through adenosine, collagen and coenzyme Q10, and enhance the elasticity and firmness of the skin.

Description

Technical Field

[0001] The invention relates to the technical field of cosmetic preparation, in particular to a whitening and anti-aging raw material and a preparation method and application thereof. Background Art

[0002] Skin whitening skin care products are also called freckle removal and whitening skin care products. They are classified as special-purpose cosmetics in my country. Whitening skin care products have always occupied a considerable share in the cosmetics market. Especially in recent years, with the development of cosmetic medicine and the improvement of economic level, skin whitening skin care products are very popular among consumers.

[0003] With the development of society, people are getting busier and busier at work, staying up late longer and longer, and having less and less time to relax. Long-term work pressure and staying up late cause their skin to be worse than that of their peers. People are becoming more and more anxious about their age and appearance, which leads to more and more frequent use of cosmetics.

[0004] The current whitening and anti-aging raw materials have certain whitening and anti-aging effects, but the deep penetration of their whitening active ingredients is poor, resulting in the whitening effect after use is not obvious enough. The safety of some whitening and anti-aging raw materials is poor. They have certain whitening effects in the short term after use, but long-term use will cause certain irritation and damage to the skin, and their safety is poor; the anti-photosensitivity effect of some current whitening and anti-aging raw materials is poor, resulting in the situation that the user's skin becomes white after use and then quickly turns dark. In summary, it is necessary to propose a whitening and anti-aging raw material and its preparation method and application to solve the above problems. Summary of the invention

[0005] The purpose of the present invention is to provide a whitening and anti-aging raw material and a preparation method and application thereof, so as to solve the problems raised in the above background technology.

[0006] To achieve the above object, the present invention provides the following technical solutions:

[0007] A whitening and anti-aging raw material, comprising, by mass ratio:

[0008] Licorice extract 6-15g

[0009] Arbutin 3-8g

[0010] Adenosine 0.5-5 g

[0011] Collagen 2-10g

[0012] Coenzyme Q10 0.5-5 g

[0013] Magnesium Vitamin C Phosphate 1-6 g

[0014] Green tea polyphenols 0.5-5 g

[0015] Fermentation liquid 30-60ml

[0016] Nanocarrier 50-100 g

[0017] 80-200 g purified water

[0018] Cosmetic base 800-1200 g

[0019] Zinc oxide 1-5 g;

[0020] The ingredients in terms of mass ratio include: 10 grams of licorice extract, 5 grams of arbutin, 2 grams of adenosine, 5 grams of collagen, 2 grams of coenzyme Q10, 3 grams of magnesium vitamin C phosphate, 2 grams of green tea polyphenols, 50 ml of fermentation liquid, 80 grams of nanocarrier, 180 grams of purified water, 1000 grams of cosmetic matrix, and 3 grams of zinc oxide.

[0021] Preferably, the liquorice extract and arbutin are prepared by mixing clean raw material powders with solvent water, then heating the mixture to 100-120° C., filtering, concentrating, purifying and drying the mixture to obtain the corresponding extracts.

[0022] Preferably, the collagen is one or more of bovine collagen, fish collagen and porcine collagen. The bovine collagen is extracted from cowhide or cow bones and obtained after hydrolysis, extraction and refining. The fish collagen is extracted from fish skin or fish scales and obtained after hydrolysis, extraction and refining. The porcine collagen is extracted from pig skin and obtained after hydrolysis, extraction and refining.

[0023] Preferably, the nanocarrier is a phospholipid vesicle, and the fermentation broth is a yeast fermentation broth.

[0024] Preferably, the cosmetic matrix comprises, by mass ratio, 12-30 grams of emulsifier, 15-40 grams of oil phase component, 20-50 parts of water phase component, 6-18 grams of functional additive, 2-6 grams of preservative and 0.5-2.5 grams of thickener, and the preparation process comprises the following steps:

[0025] Step 1: Oil phase preparation: weigh the oil phase ingredients according to the formula ratio, put them into a heat-resistant container, heat to 50-70°C, stir until all ingredients are completely dissolved, and continue stirring until evenly mixed;

[0026] Step 2: Prepare the water phase: weigh the water phase ingredients according to the formula ratio, put them into another heat-resistant container, heat to 50-70°C, and stir evenly;

[0027] Step 3: Emulsification: Slowly add the heated oil phase to the heated water phase, and stir using a high shear homogenizer or emulsifier to evenly mix the oil phase and the water phase to form a stable emulsion;

[0028] Step 4: Cooling: After emulsification is completed, slowly cool to room temperature and continue stirring during the cooling process to maintain uniformity;

[0029] Step 5: Add functional ingredients: When the emulsion cools to below 40°C, add the heat-sensitive functional ingredients and continue stirring until all ingredients are completely mixed;

[0030] Step 6: Adjust pH: Use citric acid or alkaline solution to adjust the pH value of the emulsion to 5-7 to obtain a ready-to-use cosmetic base.

[0031] Preferably, the oil phase component is one or more of vegetable oil, mineral oil, silicone oil and isononyl isononanoate, and the water phase component is one or more of deionized water, aqueous plant extract solution, glycerol and propylene glycol.

[0032] Preferably, the thickener is one or more of carbomer, xanthan gum and guar gum, the preservative is phenoxyethanol or paraben, and the functional additive is an antioxidant, a moisturizer and a fragrance.

[0033] The present invention also provides a method for preparing a whitening and anti-aging raw material, comprising the following steps:

[0034] S1, fermentation treatment: add licorice extract and green tea polyphenols to yeast fermentation liquid respectively, mix them in a ratio of 1:10, keep the rotation speed at 500 rpm, stir for 20 minutes, then ferment at 37°C for 24 hours, filter and take the fermentation filtrate;

[0035] S2, enzymatic hydrolysis: dissolve the collagen in purified water, heat to 40°C, add an appropriate amount of trypsin, and perform enzymatic hydrolysis for 3 hours. After the enzymatic hydrolysis is completed, heat to 80°C to inactivate the enzyme, and filter to obtain the collagen enzymatic hydrolysate;

[0036] S3, nanoencapsulation: dissolving arbutin, adenosine, coenzyme Q10, zinc oxide and magnesium ascorbyl phosphate in a small amount of purified water, adding the dissolved components into a nanocarrier, and performing ultrasonic treatment so that the active components are encapsulated by the nanocarrier to obtain a nanoencapsulation solution;

[0037] S4, mixing and homogenizing: mix the fermentation filtrate, collagenase hydrolysate and nano-encapsulation solution, add sodium hyaluronate, stir until completely dissolved, then slowly add the mixture into the cosmetic matrix, stir, keep the speed at 3000 rpm, and stir for 20 minutes until uniform;

[0038] S5. Homogenization and packaging: Stir the mixed emulsion at 8000 rpm for 2 hours to homogenize the emulsion. Put the homogenized emulsion into a clean container, seal it, and store it in a cool and dry place.

[0039] Compared with the prior art, the beneficial effects of the present invention are as follows: the present invention can effectively reduce melanin, brighten skin tone and whiten skin through the joint action of licorice extract, arbutin and magnesium vitamin C phosphate; can provide excellent moisturizing effect through sodium hyaluronate and fermentation liquid, and maintain the moisture and elasticity of the skin; can reduce fine lines and wrinkles through adenosine, collagen and coenzyme Q10, and enhance the elasticity and firmness of the skin; green tea polyphenols, coenzyme Q10 and magnesium vitamin C phosphate make the prepared whitening and anti-aging raw materials have a strong antioxidant effect, protect the skin from free radical damage, and the coordinated addition of licorice extract and fermentation liquid has anti-inflammatory and repairing effects, can soothe the skin and promote skin health. DETAILED DESCRIPTION

[0040] Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in the field without making any creative work shall fall within the scope of protection of the present invention.

[0041] 1. Materials;

[0042] All materials in this application are commercially available unless otherwise specified;

[0043] Among them, it should be noted that licorice extract and arbutin are obtained by mixing their clean raw material powders with solvent water, then heating the temperature to 100-120°C, filtering, concentrating, purifying and drying, and finally obtaining the corresponding extracts; the collagen is one or more of bovine collagen, fish collagen and porcine collagen, the bovine collagen is extracted from cowhide or cow bones, and is obtained after hydrolysis, extraction and refining, the fish collagen is extracted from fish skin or fish scales, and is obtained after hydrolysis, extraction and refinement, and the porcine collagen is extracted from pig skin, and is obtained after hydrolysis, extraction and refinement; the nanocarrier is phospholipid vesicles, and the fermentation broth is yeast fermentation broth.

[0044] 2. Technology;

[0045] The present invention provides a technical solution:

[0046] A whitening and anti-aging raw material comprises, by mass ratio, 6-15 grams of licorice extract, 3-8 grams of arbutin, 0.5-5 grams of adenosine, 2-10 grams of collagen, 0.5-5 grams of coenzyme Q10, 1-6 grams of magnesium vitamin C phosphate, 0.5-5 grams of green tea polyphenols, 30-60 ml of fermentation liquid, 50-100 grams of nanocarriers, 80-200 grams of purified water, 800-1200 grams of cosmetic matrix, and 1-5 grams of zinc oxide.

[0047] It should be noted that the cosmetic matrix includes, by mass ratio, 12-30 grams of emulsifier, 15-40 grams of oil phase component, 20-50 parts of water phase component, 6-18 grams of functional additives, 2-6 grams of preservatives and 0.5-2.5 grams of thickener. The preparation process includes the following steps:

[0048] Step 1: Oil phase preparation: weigh the oil phase ingredients according to the formula ratio, put them into a heat-resistant container, heat to 50-70°C, stir until all ingredients are completely dissolved, and continue stirring until evenly mixed;

[0049] Step 2: Prepare the water phase: weigh the water phase ingredients according to the formula ratio, put them into another heat-resistant container, heat to 50-70°C, and stir evenly;

[0050] Step 3: Emulsification: Slowly add the heated oil phase to the heated water phase, and stir using a high shear homogenizer or emulsifier to evenly mix the oil phase and the water phase to form a stable emulsion;

[0051] Step 4: Cooling: After emulsification is completed, slowly cool to room temperature and continue stirring during the cooling process to maintain uniformity;

[0052] Step 5: Add functional ingredients: When the emulsion cools to below 40°C, add the heat-sensitive functional ingredients and continue stirring until all ingredients are completely mixed;

[0053] Step 6: Adjust pH: Use citric acid or alkaline solution to adjust the pH value of the emulsion to 5-7 to obtain a ready-to-use cosmetic base.

[0054] A method for preparing a whitening and anti-aging raw material comprises the following steps:

[0055] S1, fermentation treatment: add licorice extract and green tea polyphenols to yeast fermentation liquid respectively, mix them in a ratio of 1:10, keep the rotation speed at 500 rpm, stir for 20 minutes, then ferment at 37°C for 24 hours, filter and take the fermentation filtrate;

[0056] S2, enzymatic hydrolysis: dissolve the collagen in purified water, heat to 40°C, add an appropriate amount of trypsin, and perform enzymatic hydrolysis for 3 hours. After the enzymatic hydrolysis is completed, heat to 80°C to inactivate the enzyme, and filter to obtain the collagen enzymatic hydrolysate;

[0057] S3, nanoencapsulation: dissolving arbutin, adenosine, coenzyme Q10, zinc oxide and magnesium ascorbyl phosphate in a small amount of purified water, adding the dissolved components into a nanocarrier, and performing ultrasonic treatment so that the active components are encapsulated by the nanocarrier to obtain a nanoencapsulation solution;

[0058] S4, mixing and homogenizing: mix the fermentation filtrate, collagenase hydrolysate and nano-encapsulation solution, add sodium hyaluronate, stir until completely dissolved, then slowly add the mixture into the cosmetic matrix, stir, keep the speed at 3000 rpm, and stir for 20 minutes until uniform;

[0059] S5. Homogenization and packaging: Stir the mixed emulsion at 8000 rpm for 2 hours to homogenize the emulsion. Put the homogenized emulsion into a clean container, seal it, and store it in a cool and dry place. Example 1

[0060] A whitening and anti-aging raw material, comprising, by mass ratio: 6 grams of licorice extract, 3 grams of arbutin, 0.5 grams of adenosine, 2 grams of collagen, 0.5 grams of coenzyme Q10, 1 gram of magnesium vitamin C phosphate, 0.5 grams of green tea polyphenols, 30 ml of fermentation liquid, 50 grams of nanocarriers, 80 grams of purified water, 800 grams of cosmetic base, and 1 gram of zinc oxide.

[0061] It should be noted that the cosmetic matrix includes, by mass ratio, 12 grams of emulsifier, 15 grams of oil phase component, 20 parts of water phase component, 6 grams of functional additive, 2 grams of preservative and 0.5 grams of thickener. The preparation process includes the following steps:

[0062] Step 1: Prepare the oil phase: weigh the oil phase ingredients according to the formula ratio, put them into a heat-resistant container, heat to 50°C, stir until all ingredients are completely dissolved, and continue stirring until evenly mixed;

[0063] Step 2: Prepare the water phase: weigh the water phase ingredients according to the formula ratio, put them into another heat-resistant container, heat to 50°C, and stir evenly;

[0064] Step 3: Emulsification: Slowly add the heated oil phase to the heated water phase, and stir using a high shear homogenizer or emulsifier to evenly mix the oil phase and the water phase to form a stable emulsion;

[0065] Step 4: Cooling: After emulsification is completed, slowly cool to room temperature and continue stirring during the cooling process to maintain uniformity;

[0066] Step 5: Add functional ingredients: When the emulsion cools to below 40°C, add the heat-sensitive functional ingredients and continue stirring until all ingredients are completely mixed;

[0067] Step 6: Adjust pH: Use citric acid or alkaline solution to adjust the pH value of the emulsion to 5 to obtain a ready-to-use cosmetic base.

[0068] A method for preparing a whitening and anti-aging raw material comprises the following steps:

[0069] S1, fermentation treatment: add licorice extract and green tea polyphenols to yeast fermentation liquid respectively, mix them in a ratio of 1:10, keep the rotation speed at 500 rpm, stir for 20 minutes, then ferment at 37°C for 24 hours, filter and take the fermentation filtrate;

[0070] S2, enzymatic hydrolysis: dissolve the collagen in purified water, heat to 40°C, add an appropriate amount of trypsin, and perform enzymatic hydrolysis for 3 hours. After the enzymatic hydrolysis is completed, heat to 80°C to inactivate the enzyme, and filter to obtain the collagen enzymatic hydrolysate;

[0071] S3, nanoencapsulation: dissolving arbutin, adenosine, coenzyme Q10, zinc oxide and magnesium ascorbyl phosphate in a small amount of purified water, adding the dissolved components into a nanocarrier, and performing ultrasonic treatment so that the active components are encapsulated by the nanocarrier to obtain a nanoencapsulation solution;

[0072] S4, mixing and homogenizing: mix the fermentation filtrate, collagenase hydrolysate and nano-encapsulation solution, add sodium hyaluronate, stir until completely dissolved, then slowly add the mixture into the cosmetic matrix, stir, keep the speed at 3000 rpm, and stir for 20 minutes until uniform;

[0073] S5. Homogenization and packaging: Stir the mixed emulsion at 8000 rpm for 2 hours to homogenize the emulsion. Put the homogenized emulsion into a clean container, seal it, and store it in a cool and dry place. Example 2

[0074] A whitening and anti-aging raw material, comprising, by mass ratio: 8 grams of licorice extract, 4 grams of arbutin, 1 gram of adenosine, 3 grams of collagen, 1 gram of coenzyme Q10, 2 grams of magnesium vitamin C phosphate, 1 gram of green tea polyphenols, 35 ml of fermentation liquid, 56 grams of nanocarriers, 90 grams of purified water, 850 grams of cosmetic base, and 2 grams of zinc oxide.

[0075] It should be noted that the cosmetic matrix includes, by mass ratio, 15 grams of emulsifier, 20 grams of oil phase component, 25 parts of water phase component, 8 grams of functional additive, 3 grams of preservative and 1 gram of thickener. The preparation process includes the following steps:

[0076] Step 1: Prepare the oil phase: weigh the oil phase ingredients according to the formula ratio, put them into a heat-resistant container, heat to 55°C, stir until all ingredients are completely dissolved, and continue stirring until evenly mixed;

[0077] Step 2: Prepare the water phase: weigh the water phase ingredients according to the formula ratio, put them into another heat-resistant container, heat to 55°C, and stir evenly;

[0078] Step 3: Emulsification: Slowly add the heated oil phase to the heated water phase, and stir using a high shear homogenizer or emulsifier to evenly mix the oil phase and the water phase to form a stable emulsion;

[0079] Step 4: Cooling: After emulsification is completed, slowly cool to room temperature and continue stirring during the cooling process to maintain uniformity;

[0080] Step 5: Add functional ingredients: When the emulsion cools to below 40°C, add the heat-sensitive functional ingredients and continue stirring until all ingredients are completely mixed;

[0081] Step 6: Adjust pH: Use citric acid or alkaline solution to adjust the pH value of the emulsion to 5.5 to obtain a ready-to-use cosmetic base.

[0082] A method for preparing a whitening and anti-aging raw material comprises the following steps:

[0083] S1, fermentation treatment: add licorice extract and green tea polyphenols to yeast fermentation liquid respectively, mix them in a ratio of 1:10, keep the rotation speed at 500 rpm, stir for 20 minutes, then ferment at 37°C for 24 hours, filter and take the fermentation filtrate;

[0084] S2, enzymatic hydrolysis: dissolve the collagen in purified water, heat to 40°C, add an appropriate amount of trypsin, and perform enzymatic hydrolysis for 3 hours. After the enzymatic hydrolysis is completed, heat to 80°C to inactivate the enzyme, and filter to obtain the collagen enzymatic hydrolysate;

[0085] S3, nanoencapsulation: dissolving arbutin, adenosine, coenzyme Q10, zinc oxide and magnesium ascorbyl phosphate in a small amount of purified water, adding the dissolved components into a nanocarrier, and performing ultrasonic treatment so that the active components are encapsulated by the nanocarrier to obtain a nanoencapsulation solution;

[0086] S4, mixing and homogenizing: mix the fermentation filtrate, collagenase hydrolysate and nano-encapsulation solution, add sodium hyaluronate, stir until completely dissolved, then slowly add the mixture into the cosmetic matrix, stir, keep the speed at 3000 rpm, and stir for 20 minutes until uniform;

[0087] S5. Homogenization and packaging: Stir the mixed emulsion at 8000 rpm for 2 hours to homogenize the emulsion. Put the homogenized emulsion into a clean container, seal it, and store it in a cool and dry place. Example 3

[0088] A whitening and anti-aging raw material, comprising, by mass ratio: 10 grams of licorice extract, 5 grams of arbutin, 2 grams of adenosine, 4 grams of collagen, 1.5 grams of coenzyme Q10, 2.5 grams of magnesium vitamin C phosphate, 2.5 grams of green tea polyphenols, 40 ml of fermentation liquid, 66 grams of nanocarriers, 100 grams of purified water, 900 grams of cosmetic base, and 3 grams of zinc oxide.

[0089] It should be noted that the cosmetic matrix includes, by mass ratio, 18 grams of emulsifier, 25 grams of oil phase component, 30 parts of water phase component, 10 grams of functional additive, 3.5 grams of preservative and 1.5 grams of thickener. The preparation process includes the following steps:

[0090] Step 1: Prepare the oil phase: weigh the oil phase ingredients according to the formula ratio, put them into a heat-resistant container, heat to 70°C, stir until all ingredients are completely dissolved, and continue stirring until evenly mixed;

[0091] Step 2: Prepare the water phase: weigh the water phase ingredients according to the formula ratio, put them into another heat-resistant container, heat to 70°C, and stir evenly;

[0092] Step 3: Emulsification: Slowly add the heated oil phase to the heated water phase, and stir using a high shear homogenizer or emulsifier to evenly mix the oil phase and the water phase to form a stable emulsion;

[0093] Step 4: Cooling: After emulsification is completed, slowly cool to room temperature and continue stirring during the cooling process to maintain uniformity;

[0094] Step 5: Add functional ingredients: When the emulsion cools to below 40°C, add the heat-sensitive functional ingredients and continue stirring until all ingredients are completely mixed;

[0095] Step 6: Adjust pH: Use citric acid or alkaline solution to adjust the pH value of the emulsion to 7 to obtain a ready-to-use cosmetic base.

[0096] A method for preparing a whitening and anti-aging raw material comprises the following steps:

[0097] S1, fermentation treatment: add licorice extract and green tea polyphenols to yeast fermentation liquid respectively, mix them in a ratio of 1:10, keep the rotation speed at 500 rpm, stir for 20 minutes, then ferment at 37°C for 24 hours, filter and take the fermentation filtrate;

[0098] S2, enzymatic hydrolysis: dissolve the collagen in purified water, heat to 40°C, add an appropriate amount of trypsin, and perform enzymatic hydrolysis for 3 hours. After the enzymatic hydrolysis is completed, heat to 80°C to inactivate the enzyme, and filter to obtain the collagen enzymatic hydrolysate;

[0099] S3, nanoencapsulation: dissolving arbutin, adenosine, coenzyme Q10, zinc oxide and magnesium ascorbyl phosphate in a small amount of purified water, adding the dissolved components into a nanocarrier, and performing ultrasonic treatment so that the active components are encapsulated by the nanocarrier to obtain a nanoencapsulation solution;

[0100] S4, mixing and homogenizing: mix the fermentation filtrate, collagenase hydrolysate and nano-encapsulation solution, add sodium hyaluronate, stir until completely dissolved, then slowly add the mixture into the cosmetic matrix, stir, keep the speed at 3000 rpm, and stir for 20 minutes until uniform;

[0101] S5. Homogenization and packaging: Stir the mixed emulsion at 8000 rpm for 2 hours to homogenize the emulsion. Put the homogenized emulsion into a clean container, seal it, and store it in a cool and dry place. Example 4

[0102] A whitening and anti-aging raw material comprises, by mass ratio, 10 grams of licorice extract, 5 grams of arbutin, 2 grams of adenosine, 5 grams of collagen, 2 grams of coenzyme Q10, 3 grams of magnesium vitamin C phosphate, 2 grams of green tea polyphenols, 50 ml of fermentation liquid, 80 grams of nanocarriers, 180 grams of purified water, 1000 grams of cosmetic base, and 3 grams of zinc oxide.

[0103] It should be noted that the cosmetic matrix includes, by mass ratio, 20 grams of emulsifier, 30 grams of oil phase component, 35 parts of water phase component, 12 grams of functional additive, 4 grams of preservative and 2 grams of thickener. The preparation process includes the following steps:

[0104] Step 1: Prepare the oil phase: weigh the oil phase ingredients according to the formula ratio, put them into a heat-resistant container, heat to 65°C, stir until all ingredients are completely dissolved, and continue stirring until evenly mixed;

[0105] Step 2: Prepare the water phase: weigh the water phase ingredients according to the formula ratio, put them into another heat-resistant container, heat to 65°C, and stir evenly;

[0106] Step 3: Emulsification: Slowly add the heated oil phase to the heated water phase, and stir using a high shear homogenizer or emulsifier to evenly mix the oil phase and the water phase to form a stable emulsion;

[0107] Step 4: Cooling: After emulsification is completed, slowly cool to room temperature and continue stirring during the cooling process to maintain uniformity;

[0108] Step 5: Add functional ingredients: When the emulsion cools to below 40°C, add the heat-sensitive functional ingredients and continue stirring until all ingredients are completely mixed;

[0109] Step 6: Adjust pH: Use citric acid or alkaline solution to adjust the pH value of the emulsion to 6 to obtain a ready-to-use cosmetic base.

[0110] A method for preparing a whitening and anti-aging raw material comprises the following steps:

[0111] S1, fermentation treatment: add licorice extract and green tea polyphenols to yeast fermentation liquid respectively, mix them in a ratio of 1:10, keep the rotation speed at 500 rpm, stir for 20 minutes, then ferment at 37°C for 24 hours, filter and take the fermentation filtrate;

[0112] S2, enzymatic hydrolysis: dissolve the collagen in purified water, heat to 40°C, add an appropriate amount of trypsin, and perform enzymatic hydrolysis for 3 hours. After the enzymatic hydrolysis is completed, heat to 80°C to inactivate the enzyme, and filter to obtain the collagen enzymatic hydrolysate;

[0113] S3, nanoencapsulation: dissolving arbutin, adenosine, coenzyme Q10, zinc oxide and magnesium ascorbyl phosphate in a small amount of purified water, adding the dissolved components into a nanocarrier, and performing ultrasonic treatment so that the active components are encapsulated by the nanocarrier to obtain a nanoencapsulation solution;

[0114] S4, mixing and homogenizing: mix the fermentation filtrate, collagenase hydrolysate and nano-encapsulation solution, add sodium hyaluronate, stir until completely dissolved, then slowly add the mixture into the cosmetic matrix, stir, keep the speed at 3000 rpm, and stir for 20 minutes until uniform;

[0115] S5. Homogenization and packaging: Stir the mixed emulsion at 8000 rpm for 2 hours to homogenize the emulsion. Put the homogenized emulsion into a clean container, seal it, and store it in a cool and dry place. Example 5

[0116] A whitening and anti-aging raw material, comprising, by mass ratio: 12 grams of licorice extract, 7 grams of arbutin, 4 grams of adenosine, 8 grams of collagen, 4 grams of coenzyme Q10, 5 grams of magnesium vitamin C phosphate, 4 grams of green tea polyphenols, 55 ml of fermentation liquid, 90 grams of nanocarriers, 190 grams of purified water, 1100 grams of cosmetic base, and 3.5 grams of zinc oxide.

[0117] It should be noted that the cosmetic matrix includes, by mass ratio, 25 grams of emulsifier, 35 grams of oil phase component, 40 parts of water phase component, 15 grams of functional additive, 5 grams of preservative and 2 grams of thickener. The preparation process includes the following steps:

[0118] Step 1: Prepare the oil phase: weigh the oil phase ingredients according to the formula ratio, put them into a heat-resistant container, heat to 68°C, stir until all ingredients are completely dissolved, and continue stirring until evenly mixed;

[0119] Step 2: Prepare the water phase: weigh the water phase ingredients according to the formula ratio, put them into another heat-resistant container, heat to 68°C, and stir evenly;

[0120] Step 3: Emulsification: Slowly add the heated oil phase to the heated water phase, and stir using a high shear homogenizer or emulsifier to evenly mix the oil phase and the water phase to form a stable emulsion;

[0121] Step 4: Cooling: After emulsification is completed, slowly cool to room temperature and continue stirring during the cooling process to maintain uniformity;

[0122] Step 5: Add functional ingredients: When the emulsion cools to below 40°C, add the heat-sensitive functional ingredients and continue stirring until all ingredients are completely mixed;

[0123] Step 6: Adjust pH: Use citric acid or alkaline solution to adjust the pH value of the emulsion to 6 to obtain a ready-to-use cosmetic base.

[0124] A method for preparing a whitening and anti-aging raw material comprises the following steps:

[0125] S1, fermentation treatment: add licorice extract and green tea polyphenols to yeast fermentation liquid respectively, mix them in a ratio of 1:10, keep the rotation speed at 500 rpm, stir for 20 minutes, then ferment at 37°C for 24 hours, filter and take the fermentation filtrate;

[0126] S2, enzymatic hydrolysis: dissolve the collagen in purified water, heat to 40°C, add an appropriate amount of trypsin, and perform enzymatic hydrolysis for 3 hours. After the enzymatic hydrolysis is completed, heat to 80°C to inactivate the enzyme, and filter to obtain the collagen enzymatic hydrolysate;

[0127] S3, nanoencapsulation: dissolving arbutin, adenosine, coenzyme Q10, zinc oxide and magnesium ascorbyl phosphate in a small amount of purified water, adding the dissolved components into a nanocarrier, and performing ultrasonic treatment so that the active components are encapsulated by the nanocarrier to obtain a nanoencapsulation solution;

[0128] S4, mixing and homogenizing: mix the fermentation filtrate, collagenase hydrolysate and nano-encapsulation solution, add sodium hyaluronate, stir until completely dissolved, then slowly add the mixture into the cosmetic matrix, stir, keep the speed at 3000 rpm, and stir for 20 minutes until uniform;

[0129] S5. Homogenization and packaging: Stir the mixed emulsion at 8000 rpm for 2 hours to homogenize the emulsion. Put the homogenized emulsion into a clean container, seal it, and store it in a cool and dry place. Example 6

[0130] A whitening and anti-aging raw material comprises, by mass ratio, 15 grams of licorice extract, 8 grams of arbutin, 5 grams of adenosine, 10 grams of collagen, 5 grams of coenzyme Q10, 6 grams of magnesium vitamin C phosphate, 5 grams of green tea polyphenols, 60 ml of fermentation liquid, 100 grams of nanocarriers, 200 grams of purified water, 1200 grams of cosmetic base, and 4 grams of zinc oxide.

[0131] It should be noted that the cosmetic matrix includes, by mass ratio, 30 grams of emulsifier, 40 grams of oil phase component, 50 parts of water phase component, 18 grams of functional additive, 6 grams of preservative and 2.5 grams of thickener. The preparation process includes the following steps:

[0132] Step 1: Prepare the oil phase: weigh the oil phase ingredients according to the formula ratio, put them into a heat-resistant container, heat to 70°C, stir until all ingredients are completely dissolved, and continue stirring until evenly mixed;

[0133] Step 2: Prepare the water phase: weigh the water phase ingredients according to the formula ratio, put them into another heat-resistant container, heat to 70°C, and stir evenly;

[0134] Step 3: Emulsification: Slowly add the heated oil phase to the heated water phase, and stir using a high shear homogenizer or emulsifier to evenly mix the oil phase and the water phase to form a stable emulsion;

[0135] Step 4: Cooling: After emulsification is completed, slowly cool to room temperature and continue stirring during the cooling process to maintain uniformity;

[0136] Step 5: Add functional ingredients: When the emulsion cools to below 40°C, add the heat-sensitive functional ingredients and continue stirring until all ingredients are completely mixed;

[0137] Step 6: Adjust pH: Use citric acid or alkaline solution to adjust the pH value of the emulsion to 7 to obtain a ready-to-use cosmetic base.

[0138] A method for preparing a whitening and anti-aging raw material comprises the following steps:

[0139] S1, fermentation treatment: add licorice extract and green tea polyphenols to yeast fermentation liquid respectively, mix them in a ratio of 1:10, keep the rotation speed at 500 rpm, stir for 20 minutes, then ferment at 37°C for 24 hours, filter and take the fermentation filtrate;

[0140] S2, enzymatic hydrolysis: dissolve the collagen in purified water, heat to 40°C, add an appropriate amount of trypsin, and perform enzymatic hydrolysis for 3 hours. After the enzymatic hydrolysis is completed, heat to 80°C to inactivate the enzyme, and filter to obtain the collagen enzymatic hydrolysate;

[0141] S3, nanoencapsulation: dissolving arbutin, adenosine, coenzyme Q10, zinc oxide and magnesium ascorbyl phosphate in a small amount of purified water, adding the dissolved components into a nanocarrier, and performing ultrasonic treatment so that the active components are encapsulated by the nanocarrier to obtain a nanoencapsulation solution;

[0142] S4, mixing and homogenizing: mix the fermentation filtrate, collagenase hydrolysate and nano-encapsulation solution, add sodium hyaluronate, stir until completely dissolved, then slowly add the mixture into the cosmetic matrix, stir, keep the speed at 3000 rpm, and stir for 20 minutes until uniform;

[0143] S5. Homogenization and packaging: Stir the mixed emulsion at 8000 rpm for 2 hours to homogenize the emulsion. Put the homogenized emulsion into a clean container, seal it, and store it in a cool and dry place.

[0144] 3. Experiment;

[0145] ① Experiment 1: Study the effects of the creams made from the whitening and anti-aging raw materials prepared in Examples 1 to 6 on skin whitening and anti-aging effects.

[0146] Experimental materials: whitening and anti-aging raw materials prepared in Examples 1 to 6; subjects: 30 people, aged 20-40 years old, divided into 6 groups according to Examples 1 to 6, 5 people in each group; instruments: skin tester;

[0147] Experimental steps: 1. The whitening and anti-aging raw materials prepared in Examples 1 to 6 are uniformly mixed, and then added into the base cream to prepare a cream containing the whitening and anti-aging raw materials;

[0148] 2. Grouping: The subjects were randomly divided into 6 groups, and the creams containing the whitening and anti-aging raw materials prepared in Examples 1 to 6 were used;

[0149] 3. Usage: The subjects should apply the cream on their face after cleansing every morning and evening for 4 consecutive weeks;

[0150] 4. Data collection: Measure the moisture, elasticity and whitening effect of the subjects’ skin every week and record the data.

[0151] Data analysis: Compare the changes in skin indicators of the group members of Example 1 to Example 6 before and after use, and analyze the effects of the cream containing whitening and anti-aging ingredients on the skin. The results are shown in Table 1 to Table 6;

[0152] Table 1 Skin index changes in Example 1

[0153]

[0154] Table 2 Skin index changes in Example 2

[0155]

[0156] Table 3 Skin index changes in Example 3

[0157]

[0158] Table 4 Skin index changes in Example 4

[0159]

[0160] Table 5 Skin index changes in Example 5

[0161]

[0162] Table 6 Skin index changes in Example 6

[0163]

[0164] Experimental conclusion: The skin moisture content of the whitening and anti-aging raw material prepared using this embodiment 4 is significantly increased, the skin elasticity is better than that of other embodiments, and the skin whitening effect is better. As the product usage time increases, the skin moisture content of the whitening and anti-aging raw material prepared in embodiment 4 is the highest, the skin elasticity is the best, and the whitening degree is the highest, so it is concluded that the use effect of embodiment 4 of the present invention is significantly better than that of other embodiments.

[0165] ② Experiment 2: Study the effects of creams containing whitening and anti-aging ingredients on skin whitening and anti-aging effects.

[0166] Experimental materials: whitening and anti-aging raw materials prepared in Example 4 of the present invention; base cream without whitening and anti-aging raw materials; subjects: 30 people, aged 20-40 years old, divided into an experimental group and a control group, 15 people in each group; instruments: skin tester (to measure skin moisture, elasticity, and whitening effect);

[0167] Experimental steps:

[0168] 1. Preparation of cream: The whitening and anti-aging raw materials prepared in Example 4 of the present invention are uniformly mixed and added into a base cream to prepare a cream containing the whitening and anti-aging raw materials.

[0169] 2. Grouping: The subjects were randomly divided into two groups. The experimental group used a cream containing whitening and anti-aging ingredients, and the control group used a base cream without whitening and anti-aging ingredients.

[0170] 3. Usage: The subjects should apply the cream on their face after cleansing in the morning and evening every day for 4 weeks.

[0171] 4. Data collection: Measure the moisture, elasticity and whitening effect of the subjects’ skin every week and record the data.

[0172] Data analysis: Compare the changes of various skin indicators of the experimental group and the control group before and after use, and analyze the effects of the cream containing whitening and anti-aging ingredients on the skin. The experimental results are shown in Table 7;

[0173] Table 7 Changes of skin indexes in the experimental group and the control group

[0174]

[0175] Experimental conclusion: Compared with the control group, the experimental group had a significantly increased skin moisture content using the whitening and anti-aging raw materials prepared in the experimental group, better skin elasticity than other embodiments, and better skin whitening effect. As the product usage time increases, the whitening and anti-aging raw materials prepared in the experimental group have the highest skin moisture content, the best skin elasticity and the highest whitening degree, thus concluding that the whitening and anti-aging raw materials prepared by the present invention have a significantly better use effect than those of the control group.

[0176] In summary, the present invention can effectively reduce melanin, brighten skin tone and whiten skin through the combined effects of licorice extract, arbutin and magnesium vitamin C phosphate; can provide excellent moisturizing effect and maintain skin moisture and elasticity through sodium hyaluronate and fermentation liquid; can reduce fine lines and wrinkles and enhance skin elasticity and firmness through adenosine, collagen and coenzyme Q10; green tea polyphenols, coenzyme Q10 and magnesium vitamin C phosphate make the prepared whitening and anti-aging raw materials have a strong antioxidant effect, protect the skin from free radical damage, and the coordinated addition of licorice extract and fermentation liquid has anti-inflammatory and repairing effects, can soothe the skin and promote skin health.

[0177] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is limited by the appended claims and their equivalents.

Claims

1. A whitening and anti-aging raw material, comprising, by mass ratio: It is characterized in that The ingredients in terms of mass ratio include: 10 grams of licorice extract, 5 grams of arbutin, 2 grams of adenosine, 5 grams of collagen, 2 grams of coenzyme Q10, 3 grams of magnesium vitamin C phosphate, 2 grams of green tea polyphenols, 50 ml of fermentation liquid, 80 grams of nanocarrier, 180 grams of purified water, 1000 grams of cosmetic matrix, and 3 grams of zinc oxide.

2. A whitening and anti-aging raw material according to claim 1, characterized in that: The liquorice extract and arbutin are prepared by mixing clean raw material powders with solvent water, heating the mixture to 100-120° C., filtering, concentrating, purifying and drying the mixture to obtain the corresponding extracts.

3. The whitening and anti-aging raw material according to claim 1, characterized in that: The collagen is one or more of bovine collagen, fish collagen and porcine collagen. The bovine collagen is extracted from cowhide or cow bone and obtained after hydrolysis, extraction and purification. The fish collagen is extracted from fish skin or fish scale and obtained after hydrolysis, extraction and purification. The porcine collagen is extracted from pig skin and obtained after hydrolysis, extraction and purification.

4. The whitening and anti-aging raw material according to claim 1, characterized in that: The nanocarrier is a phospholipid vesicle, and the fermentation broth is a yeast fermentation broth.

5. The whitening and anti-aging raw material according to claim 1, characterized in that: The cosmetic matrix comprises, by mass ratio, 12-30 grams of an emulsifier, 15-40 grams of an oil phase component, 20-50 parts of an aqueous phase component, 6-18 grams of a functional additive, 2-6 grams of a preservative and 0.5-2.5 grams of a thickener. The preparation process comprises the following steps: Step 1: Prepare the oil phase: weigh the oil phase ingredients according to the formula ratio, put them into a heat-resistant container, heat to 50-70°C, stir until all ingredients are completely dissolved, and continue stirring until evenly mixed; Step 2: Prepare the water phase: weigh the water phase ingredients according to the formula ratio, put them into another heat-resistant container, heat to 50-70°C, and stir evenly; Step 3: Emulsification: Slowly add the heated oil phase into the heated water phase and stir using a high shear homogenizer or emulsifier to evenly mix the oil phase and the water phase to form a stable emulsion; Step 4: Cooling: After emulsification is completed, slowly cool to room temperature and continue stirring during the cooling process to maintain uniformity; Step 5: Add functional additive ingredients: When the emulsion cools to below 40°C, add the functional additive ingredients and continue stirring until all ingredients are completely mixed; Step 6: Adjust pH: Use citric acid or alkaline solution to adjust the pH value of the emulsion to 5-7 to obtain a ready-to-use cosmetic matrix; The functional additives are antioxidants, moisturizers and essences.

6. A whitening and anti-aging raw material according to claim 5, characterized in that: The oil phase component is one or more of vegetable oil, mineral oil, silicone oil and isononyl isononanoate, and the water phase component is one or more of deionized water, plant extract aqueous solution, glycerol and propylene glycol.

7. The whitening and anti-aging raw material according to claim 5, characterized in that: The thickener is one or more of carbomer, xanthan gum and guar gum, and the preservative is phenoxyethanol or parahydroxyformate.

8. A method for preparing a whitening and anti-aging raw material, comprising the whitening and anti-aging raw material according to any one of claims 1 to 7, characterized in that: The steps include: S1, fermentation treatment: add licorice extract and green tea polyphenols to yeast fermentation liquid respectively, mix them in a ratio of 1:10, keep the rotation speed at 500 rpm, stir for 20 minutes, then ferment at 37°C for 24 hours, filter and take the fermentation filtrate; S2, enzymatic hydrolysis: dissolve the collagen in purified water, heat to 40°C, add an appropriate amount of trypsin, and perform enzymatic hydrolysis for 3 hours. After the enzymatic hydrolysis is completed, heat to 80°C to inactivate the enzyme, and filter to obtain the collagen enzymatic hydrolysate; S3, nanoencapsulation: dissolving arbutin, adenosine, coenzyme Q10, zinc oxide and magnesium ascorbyl phosphate in a small amount of purified water, adding the dissolved components into a nanocarrier, and performing ultrasonic treatment so that the active components are encapsulated by the nanocarrier to obtain a nanoencapsulation solution; S4, mixing and homogenizing: mix the fermentation filtrate, collagenase hydrolysate and nano-encapsulation solution, add sodium hyaluronate, stir until completely dissolved, then slowly add the mixture into the cosmetic matrix, stir, keep the speed at 3000 rpm, and stir for 20 minutes until uniform; S5. Homogenization and packaging: Stir the mixed emulsion at 8000 rpm for 2 hours to homogenize the emulsion. Put the homogenized emulsion into a clean container, seal it, and store it in a cool and dry place.

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