Small animal muscle strength detection device and method

Abstract

The present invention relates to the technical field of scientific experimental instruments, and specifically discloses a small animal muscle strength detection device and method, which are used to solve the problem of inconvenient observation and measurement in the prior art; the device includes a test box, a test cavity for testing is provided inside the test box, a bottom blocking component is provided at the lower opening of the test box, a top opening is provided at the upper end of the test box, a positioning mechanism for binding a mouse is slidably provided at the upper end of the top opening, a test base is provided at one end of the test box, and a muscle strength testing mechanism for testing the tension of the positioning mechanism is provided on the test base. The present invention is designed in response to existing needs, and can limit the running direction of the mouse to ensure the accuracy of the strength test, and can also quickly and conveniently fix the mouse, simplifying the operation process. When performing a strength test, the maximum value of the mouse's pulling can also be locked, which is convenient for later readings.

Description

Technical Field

[0001] The invention relates to the technical field of scientific experimental instruments, in particular to a small animal muscle strength detection device and method. Background Art

[0002] According to statistics, the number of deaths caused by chronic non-communicable diseases such as cardiovascular and cerebrovascular diseases, cancer, chronic respiratory diseases, and diabetes accounts for 88% of the total number of deaths, and the disease burden caused by them accounts for more than 70% of the total disease burden. Based on the above situation, it is proposed to "implement the National Fitness Action" to strengthen the continuous deepening of exercise in disease prevention and treatment. Since the effective physiological mechanism of exercise on the human body is still unclear, in order to solve this problem, the human training method is applied to animals, and its physiological mechanism is studied from animals to achieve a reference effect. At present, there are all kinds of equipment used to study human training methods, but there is a lack of animal exercise training, so the exercise method is subject to many restrictions. In order to solve the problem of weight-bearing exercise training for mice, the existing patent announcement number CN211671905U discloses a mouse weight-bearing running trainer, which can be tied to the waist of the mouse, will not cause damage to the mouse, and make the mouse run with weight, but this device is not easy to control the direction of the mouse's running during actual operation, which is not convenient for observation of the experiment, and it is impossible to measure the muscle strength of the mouse, and it is not convenient to adjust the measurement intensity.

[0003] Based on this, a small animal muscle strength detection device and method are now provided, which can eliminate the disadvantages of existing devices. Summary of the invention

[0004] The purpose of the present invention is to provide a small animal muscle strength detection device and method, which solves the problem of inconvenient observation and measurement in the prior art.

[0005] To achieve the above object, the present invention provides the following technical solutions:

[0006] The small animal muscle strength detection device comprises a test box, wherein a test inner cavity for testing is arranged inside the test box, a bottom blocking component is arranged at the opening position of the lower end of the test box, a top opening is arranged at the upper end of the test box, a positioning mechanism for tying a mouse is slidably arranged at the upper end position of the top opening, a test base is arranged at one end of the test box, and a muscle strength testing mechanism for testing the tension of the positioning mechanism is arranged on the test base, so that the mouse can be fixed on the positioning mechanism.

[0007] On the basis of the above technical solution, the present invention also provides the following optional technical solution:

[0008] In an optional solution: a side door is opened on the side of the test box, and a movable door is slidably matched at the position of the side door. Limit blocks are symmetrically provided on the upper and lower sides of the test box, and the sliding gap formed between the two limit blocks matches the movable door. The movable door and the test box are made of transparent materials.

[0009] In an optional scheme: the muscle strength testing mechanism includes an elastic vertical plate arranged at the upper end of the test base, an elastic sliding rod is provided at the upper end of the elastic vertical plate for horizontal sliding, and a scale bar is provided on the elastic sliding rod for easy reading, a fixed round block is provided at the outer end of the elastic sliding rod, the fixed round block is connected to the elastic vertical plate by a test spring, a locking bolt is provided at the other end of the elastic sliding rod, a test block is provided on the side of the positioning slide facing the test base, and a test pull ring matching the locking bolt is provided at the end of the test block.

[0010] In an optional solution: a positioning socket is provided at the upper end of the test base, and the lower end of the elastic vertical plate matches the positioning socket.

[0011] In an optional scheme: the positioning mechanism includes a positioning slide slidably set at the top opening position, the two sides of the lower end of the positioning slide are connected to the test box by sliding parts, the upper end of the positioning slide is provided with a clamping slide groove, two clamping slides are slidably provided in the clamping slide groove, the clamping slide is an I-shaped structure, each clamping slide is provided with a vertical sliding rod for vertical sliding, each vertical slide is provided with a binding ring for clamping the mouse body at the lower end, the binding ring is a clamping ring, a locking bolt for locking the vertical slide rod is screwed on the side of the clamping slide, a first limit member for limiting the outward sliding of the clamping slide is provided between the clamping slide and the positioning slide, and a second limit member is provided between the positioning slide and the test box.

[0012] In an optional scheme: the second limiting member includes a second mounting side block connected to the positioning slide, a second limiting vertical rod is slidably provided on the second mounting side block, a second locking bevel block is provided at the lower end of the second limiting vertical rod, the second pulling block at the upper end of the second limiting vertical rod is connected to the second mounting side block through a second reset spring, a side strip plate is provided on the outer side of the upper end of the test box, and a side strip convex strip surface corresponding to the second locking bevel block is provided on the side strip plate.

[0013] In an optional scheme: the first limiting member includes a first mounting side plate arranged on the side of the clamping slider, a first limiting vertical rod is vertically slidably provided on the first mounting side plate, a first pulling block is provided at the upper end of the first limiting vertical rod, a first reset block on the side of the first pulling block is connected to the first mounting side plate through a first reset spring, a first locking bevel block is provided at the lower end of the first limiting vertical rod, and a clamping groove surface corresponding to the first locking bevel block is provided at the upper end of the positioning slide, and the bevel surface of the first locking bevel block is arranged facing inward.

[0014] In an optional solution: the sliding member includes a sliding block arranged at the lower end of the positioning slide, the sliding block is provided with a sliding hole, and a horizontal sliding rod is provided on the outer side of the upper end of the test box and passes through the sliding hole, and the two ends of the horizontal sliding rod are connected to the test box through a fixed block.

[0015] In an optional solution: the bottom blocking component includes a support platform, which is connected to the test cavity by a connecting frame group, and a support leg is respectively provided at the four corners of the lower end of the support platform, and two transmission rollers are rotatably provided on both sides of the upper end of the support platform, and the two transmission rollers are connected by a transmission belt transmission, and one of the transmission rollers is connected to a treadmill motor for driving its rotation.

[0016] In an optional solution: the connecting frame assembly includes a lifting push rod arranged on the outside of the support platform, the output end of the lifting push rod is provided with a lifting connecting rod, and the upper end of the lifting connecting rod is connected to the connecting side block on the outside of the test box.

[0017] Compared with the prior art, the present invention has the following beneficial effects:

[0018] 1. The present invention is designed according to existing needs, and can limit the running direction of the mouse to ensure the accuracy of the strength test. It is also convenient and quick to fix the mouse, simplifying the operation process. When performing the strength test, the maximum value of the mouse's pulling can also be locked, which is convenient for later readings.

[0019] 2. The present invention constructs a bottom blocking component at the bottom of the test box to form a treadmill-like structure, which can warm up the mice before the test, exercise the mice, and detect the running speed of the mice, thereby achieving multiple goals at one stroke and enriching the experimental data. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a schematic diagram of the structure of the present invention.

[0021] Figure 2 It is a structural schematic diagram of the back side of the present invention.

[0022] Figure 3 It is a schematic diagram of the positioning mechanism structure of the present invention.

[0023] Figure 4 It is a schematic diagram of the structure of the first limiting member of the present invention.

[0024] Figure 5 It is a schematic diagram of the structure of the second limit member of the present invention.

[0025] Figure 6 It is a structural schematic diagram of the muscle strength testing mechanism of the present invention.

[0026] Figure 7 It is a schematic diagram of the structure of the connecting frame group of the present invention.

[0027] Reference numerals: test box 100, top opening 101, limit block 102, movable door 103, side door 104, test inner cavity 105, side strip board 106, side strip convex strip surface 107, lifting connecting rod 108, lifting push rod 109, connecting side block 110;

[0028] Positioning mechanism 200, positioning slide 201, vertical slide bar 202, clamping slide 203, test block 204, test pull ring 205, locking bolt 206, sliding block 207, sliding hole 208, binding ring 209, silicone layer 210, clamping slide groove 211, clamping groove surface 212, first stopper 213, second stopper 214;

[0029] A first pull block 220, a first limit vertical rod 219, a first reset block 218, a first reset spring 217, a first mounting side plate 216, and a first locking bevel block 215;

[0030] A second pulling block 225, a second return spring 224, a second mounting side block 223, a second limiting vertical rod 222, and a second locking oblique block 221;

[0031] Test base 300, muscle strength test mechanism 301, locking bolt 302, elastic slide bar 303, test spring 304, fixed round block 305, elastic vertical plate 306;

[0032] Support legs 401 , support platform 400 , running motor 402 , transmission roller 403 , transmission belt 404 . DETAILED DESCRIPTION

[0033] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0034] Example 1

[0035] like Figure 1-Figure 7As shown, the embodiment of the present invention provides a small animal muscle strength detection device, including a test box 100, wherein a test cavity 105 for testing is provided inside the test box 100, a bottom blocking component is provided at the opening position of the lower end of the test box 100, a top opening 101 is provided at the upper end of the test box 100, a positioning mechanism 200 for binding a mouse is slidably provided at the upper end position of the top opening 101, and a test base 300 is provided at one end of the test box 100, and a muscle strength testing mechanism 301 for testing the pulling force of the positioning mechanism 200 is provided on the test base 300, so that the mouse can be fixed on the positioning mechanism 200, so that the mouse runs at the upper end of the bottom blocking component, and then the positioning mechanism 200 is pulled to slide, and the mouse strength is observed through the muscle strength testing mechanism 301, thereby completing the detection of the mouse:

[0036] The test box 100 has a side door 104, and a movable door 103 is slidably matched at the side door 104. Limit blocks 102 are symmetrically arranged on the upper and lower sides of the test box 100, and the sliding gap formed between the two limit blocks 102 matches the movable door 103, so that it is convenient to open the test box 100 from the side and to take and put the mouse.

[0037] The muscle strength testing mechanism 301 includes an elastic vertical plate 306 arranged at the upper end of the test base 300, an elastic slide bar 303 is arranged on the upper end of the elastic vertical plate 306 for horizontal sliding, and a scale bar is arranged on the elastic slide bar 303 for easy reading, a fixed round block 305 is arranged at the outer end of the elastic slide bar 303, and the fixed round block 305 is connected to the elastic vertical plate 306 through a test spring 304, and a locking bolt 302 is arranged at the other end of the elastic slide bar 303, and a test block 204 is arranged on the side of the positioning slide 201 facing the test base 300, and a test pull ring 205 matching the locking bolt 302 is arranged at the end of the test block 204. In actual use, the corresponding number of muscle strength testing mechanisms 301 are selected according to the volume of the test mouse, and the corresponding resistance value is matched for the positioning mechanism 200 by inserting the locking bolt 302 into the test pull ring 205;

[0038] The positioning mechanism 200 includes a positioning slide 201 slidably arranged at the top opening 101 position, the lower ends of the positioning slide 201 are connected to the test box 100 by sliding members, the upper end of the positioning slide 201 is provided with a clamping slot 211, and two clamping sliders 203 are slidably arranged in the clamping slot 211. The clamping sliders 203 are I-shaped structures, and each clamping slider 203 is provided with a vertical sliding rod 202 for vertical sliding, and each vertical sliding rod 202 is provided with a binding ring 209 for clamping the mouse body at the lower end. A silicone layer 210 is provided on the side, the binding ring 209 can be a Velcro or a clamping ring, so as to quickly fix the mouse, a locking bolt 206 for locking the vertical slide bar 202 is screwed on the side of the clamping slider 203, a first limiting member 213 for limiting the outward sliding of the clamping slider 203 is provided between the clamping slider 203 and the positioning slide 201, and a second limiting member 214 is provided between the positioning slide 201 and the test box 100, and the sliding distance of the positioning slide 201 is limited by the second limiting member 214, so as to lock the pulling amplitude of the mouse, so as to facilitate the staff to read accurately;

[0039] The second limiting member 214 includes a second mounting side block 223 connected to the positioning slide 201, a second limiting vertical rod 222 is slidably provided on the second mounting side block 223, a second locking bevel block 221 is provided at the lower end of the second limiting vertical rod 222, a second pull block 225 at the upper end of the second limiting vertical rod 222 is connected to the second mounting side block 223 via a second reset spring 224, a side strip plate 106 is provided on the outer side of the upper end of the test box 100, and a side strip convex surface 107 corresponding to the second locking bevel block 221 is provided on the side strip plate 106, so that when the mouse pulls the positioning slide 201 to slide on the upper end of the test box 100, the side strip convex surface 107 is connected to the second locking bevel block 221, so that the positioning slide 201 can only move forward and not backward, and the maximum forward value is the maximum force of the mouse, thereby locking the detection value for convenient recording;

[0040] The first limiting member 213 includes a first mounting side plate 216 arranged on the side of the clamping slider 203, a first limiting vertical rod 219 is vertically slidably provided on the first mounting side plate 216, a first pulling block 220 is provided on the upper end of the first limiting vertical rod 219, a first reset block 218 on the side of the first pull block 220 is connected to the first mounting side plate 216 through a first reset spring 217, a first locking bevel 215 is provided at the lower end of the first limiting vertical rod 219, a clamping groove surface 212 corresponding to the first locking bevel 215 is provided at the upper end of the positioning slide 201, and the first locking bevel 215 is arranged with an inclined surface facing inward. Under the action of the first reset spring 217, the first locking bevel 215 is pressed and contacted with the surface of the clamping groove surface 212. Only when the clamping slider 203 slides inwardly along the positioning slide 201, the first locking bevel 215 will not block the displacement, so as to quickly lock the clamping gap between the two binding rings 209;

[0041] The sliding member includes a sliding block 207 arranged at the lower end of the positioning slide 201, and a sliding hole 208 is provided on the sliding block 207. A horizontal sliding rod penetrating the sliding hole 208 is provided on the outer side of the upper end of the test box 100. The two ends of the horizontal sliding rod are connected to the test box 100 through a fixing block, so that the positioning slide 201 can slide along the horizontal rod at the top opening 101;

[0042] The bottom blocking component includes a support platform 400, which is connected to the test inner cavity 105 through a connecting frame group, and a support leg 401 is respectively provided at the four corners of the lower end of the support platform 400, and two transmission rollers 403 are rotatably provided on both sides of the upper end of the support platform 400, and the two transmission rollers 403 are connected to each other through a transmission belt 404, and one of the transmission rollers 403 is connected to a treadmill motor 402 for driving the transmission roller 403 to rotate. Under the drive of the treadmill motor 402, the transmission roller 403 drives the transmission belt 404 to rotate, thereby driving the mouse at the upper end of the transmission belt 404 to run, so as to exercise the mouse, and also to make the transmission belt 404 rotate slightly to warm up the mouse for tensile test, thereby improving the test effect;

[0043] Example 2

[0044] The difference from Example 1 is that the connecting frame assembly includes a lifting push rod 109 arranged on the outside of the support platform 400, and the output end of the lifting push rod 109 is provided with a lifting connecting rod 108. The upper end of the lifting connecting rod 108 is connected to the connecting side block 110 on the outside of the test box 100. The lifting connecting rod 108 is extended by the lifting push rod 109, thereby adjusting the distance between the test box 100 and the support platform 400.

[0045] Example 3

[0046] The difference from Example 2 is that:

[0047] The upper end of the test base 300 is provided with a positioning socket, and the lower end of the elastic vertical plate 306 matches the positioning socket, so that it is convenient to disassemble and assemble the muscle strength testing mechanism 301;

[0048] Working principle: In actual use, first select the corresponding number of muscle strength test mechanisms 301 according to the expected pulling force range of the mouse's body size, insert the locking bolt 302 into the test pull ring 205 to match the corresponding resistance value for the positioning mechanism 200, place the mouse inside the test box 100, and then push the two clamping sliders 203 closer to each other so that the two binding rings 209 clamp the mouse to complete the quick fixation. As the mouse runs, the mouse will pull the positioning slide 201 through the binding ring 209 and the vertical slide bar 202, so that the positioning slide 201 slides along the upper end of the test box 100, and at this time the locking bolt 302 will be pulled and locked. The tightening bolt 302 will drive the elastic slide bar 303 to slide along the upper end of the elastic vertical plate 306, thereby compressing the test spring 304. When the side strip convex surface 107 and the second locking bevel 221 match, the positioning slide 201 will not retreat, but will only be limited to the maximum distance the positioning slide 201 moves forward. The staff will record the readings. During the test, the running motor 402 can also be used to drive the transmission roller 403 and the transmission belt 404 to rotate, so as to test the running speed of the mouse and further complete the detection of the mouse's strength. In addition, the present application can also use the rotation of the transmission belt 404 to warm up the mouse to improve the accuracy of the test.

[0049] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A small animal muscle strength testing device, comprising a testing box (100), characterized in that: The test box (100) is provided with a test cavity (105) for testing, a bottom blocking component is provided at the lower opening of the test box (100), a top opening (101) is provided at the upper end of the test box (100), a positioning mechanism (200) for tying a mouse is slidably provided at the upper end of the top opening (101), a test base (300) is provided at one end of the test box (100), and a muscle strength testing mechanism (301) for testing the pulling force of the positioning mechanism (200) is provided on the test base (300); The muscle strength testing mechanism (301) comprises an elastic vertical plate (306) arranged at the upper end of the testing base (300); an elastic sliding rod (303) is horizontally slidably arranged at the upper end of the elastic vertical plate (306); a scale bar is arranged on the elastic sliding rod (303) for easy reading; a fixed round block (305) is arranged at the outer end of the elastic sliding rod (303); the fixed round block (305) is connected to the elastic vertical plate (306) via a testing spring (304); a locking bolt (302) is arranged at the other end of the elastic sliding rod (303); a testing block (204) is arranged on the side of the positioning slide (201) facing the testing base (300); a testing pull ring (205) matching the locking bolt (302) is arranged at the end of the testing block (204); The positioning mechanism (200) comprises a positioning slide (201) slidably arranged at the position of the top opening (101); the lower ends of the positioning slide (201) are connected to the test box (100) via sliding members; the upper end of the positioning slide (201) is provided with a clamping slide groove (211); two clamping slide blocks (203) are slidably arranged in the clamping slide groove (211); the clamping slide blocks (203) are of an I-shaped structure; each clamping slide block (203) is provided with a vertical sliding rod (202) for vertical sliding movement; each A binding ring (209) for clamping the mouse body is provided at the lower end of the vertical slide bar (202), and the binding ring (209) is a clamping ring. A locking bolt (206) for locking the vertical slide bar (202) is screwed on the side of the clamping slide bar (203). A first limiting member (213) for limiting the clamping slide bar (203) from sliding outward is provided between the clamping slide bar (203) and the positioning slide seat (201), and a second limiting member (214) is provided between the positioning slide seat (201) and the test box (100).

2. The small animal muscle strength detection device according to claim 1, characterized in that: A side door (104) is provided on the side of the test box (100), and a movable door (103) is slidably matched at the position of the side door (104). Limit blocks (102) are symmetrically provided on the upper and lower sides of the test box (100), and a sliding gap formed between the two limit blocks (102) matches the movable door (103). The movable door (103) and the test box (100) are made of transparent materials.

3. The small animal muscle strength detection device according to claim 2, characterized in that: The second limiting member (214) comprises a second mounting side block (223) connected to the positioning slide (201); a second limiting vertical rod (222) is slidably provided on the second mounting side block (223); a second locking bevel block (221) is provided at the lower end of the second limiting vertical rod (222); a second pulling block (225) at the upper end of the second limiting vertical rod (222) is connected to the second mounting side block (223) via a second reset spring (224); a side strip plate (106) is provided on the outer side of the upper end of the test box (100); and a side strip convex strip surface (107) corresponding to the second locking bevel block (221) is provided on the side strip plate (106).

4. The small animal muscle strength detection device according to claim 3, characterized in that: The first limiting member (213) comprises a first mounting side plate (216) arranged on the side of the clamping slide block (203); a first limiting vertical rod (219) is vertically slidably provided on the first mounting side plate (216); a first pulling block (220) is provided at the upper end of the first limiting vertical rod (219); a first reset block (218) on the side of the first pulling block (220) is connected to the first mounting side plate (216) via a first reset spring (217); a first locking bevel block (215) is provided at the lower end of the first limiting vertical rod (219); a clamping groove surface (212) corresponding to the first locking bevel block (215) is provided at the upper end of the positioning slide seat (201); and the bevel surface of the first locking bevel block (215) is arranged facing inward.

5. The small animal muscle strength detection device according to claim 4, characterized in that: The sliding member comprises a sliding block (207) arranged at the lower end of the positioning slide (201), a sliding hole (208) being provided on the sliding block (207), a horizontal sliding rod penetrating the sliding hole (208) being provided on the outer side of the upper end of the test box (100), and two ends of the horizontal sliding rod are connected to the test box (100) via fixing blocks.

6. The small animal muscle strength detection device according to claim 5, characterized in that: The bottom blocking component comprises a support platform (400), the support platform (400) is connected to the test inner cavity (105) via a connecting frame group, a support leg (401) is respectively provided at the four corners of the lower end of the support platform (400), two transmission rollers (403) are rotatably provided on both sides of the upper end of the support platform (400), the two transmission rollers (403) are connected to each other via a transmission belt (404), and one of the transmission rollers (403) is connected to a treadmill motor (402) for driving the transmission roller (403) to rotate.

7. The small animal muscle strength detection device according to claim 6, characterized in that: The connecting frame assembly comprises a lifting push rod (109) arranged outside the support platform (400), the output end of the lifting push rod (109) is provided with a lifting connecting rod (108), and the upper end of the lifting connecting rod (108) is connected to a connecting side block (110) outside the test box (100).

8. A method for testing the small animal muscle strength detection device according to claim 7, characterized in that: The following steps are involved: Step 1: First, according to the expected pulling force range of the mouse body, a corresponding number of muscle strength testing mechanisms (301) are selected, and the locking bolt (302) is inserted into the test pull ring (205), thereby matching the corresponding resistance value for the positioning mechanism (200); Step 2: Place the mouse inside the test box (100), and then push the two clamping sliders (203) closer to each other so that the two binding rings (209) clamp the mouse to complete the quick fixation. As the mouse runs, the mouse will pull the positioning slide (201) through the binding ring (209) and the vertical slide bar (202), so that the positioning slide (201) slides along the upper end of the test box (100). At this time, the locking bolt (302) will be pulled, and the locking bolt (302) will drive the elastic slide bar (303) to slide along the upper end of the elastic vertical plate (306), thereby compressing the test spring (304). When the side strip convex strip surface (107) and the second locking bevel (221) match, the positioning slide (201) will not retreat, but will only be limited to the maximum distance that the positioning slide (201) moves forward. The staff will record the readings.

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