Cyclic dinucleotide compounds, agonists, and uses of cyclic dinucleotide compounds, a medicament

By using cyclic dinucleotide compounds and non-nucleoside interferon gene stimulating factor agonists, the problems of pest resistance and environmental pollution in pest control have been solved, achieving selective feeding rejection and insecticidal activity in insects, and providing a new method for green pest control.

CN118684723BActive Publication Date: 2026-06-02NANKAI UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
NANKAI UNIV
Filing Date
2024-05-24
Publication Date
2026-06-02

AI Technical Summary

Technical Problem

Existing chemical insecticides have problems such as increased pest resistance, disruption of ecological balance, and pesticide residues in pest control. Furthermore, there is insufficient understanding of the physiological regulatory mechanisms of cyclic dinucleotides in insects, and a lack of green and effective control methods.

Method used

Provides cyclic dinucleotide compounds and their pharmaceutically acceptable salts and non-nucleoside interferon gene stimulating factor agonists for selective feeding rejection and pest control in insects, with specific structures represented by Formula I, Formula II or Formula III, and prepared into solutions, powders, emulsions, suspensions or granules in combination with agonists diABZI-1, MSA-2, and SR-717.

Benefits of technology

It achieves selective rejection and killing of pests, has good insecticidal activity, reduces environmental pollution and threats to human health, and provides a green and effective means of pest control.

✦ Generated by Eureka AI based on patent content.

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Abstract

The application relates to the technical field of pesticides, and discloses a cyclic dinucleotide compound, an agonist, application of the cyclic dinucleotide compound and a medicament. The cyclic dinucleotide compound has a structure as shown in formula I, formula II or formula III. The cyclic dinucleotide compound provided by the application has selective antifeeding activity on insects and good insecticidal activity.
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