Cyclic dinucleotide compounds, agonists, and uses of cyclic dinucleotide compounds, a medicament
By using cyclic dinucleotide compounds and non-nucleoside interferon gene stimulating factor agonists, the problems of pest resistance and environmental pollution in pest control have been solved, achieving selective feeding rejection and insecticidal activity in insects, and providing a new method for green pest control.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- NANKAI UNIV
- Filing Date
- 2024-05-24
- Publication Date
- 2026-06-02
AI Technical Summary
Existing chemical insecticides have problems such as increased pest resistance, disruption of ecological balance, and pesticide residues in pest control. Furthermore, there is insufficient understanding of the physiological regulatory mechanisms of cyclic dinucleotides in insects, and a lack of green and effective control methods.
Provides cyclic dinucleotide compounds and their pharmaceutically acceptable salts and non-nucleoside interferon gene stimulating factor agonists for selective feeding rejection and pest control in insects, with specific structures represented by Formula I, Formula II or Formula III, and prepared into solutions, powders, emulsions, suspensions or granules in combination with agonists diABZI-1, MSA-2, and SR-717.
It achieves selective rejection and killing of pests, has good insecticidal activity, reduces environmental pollution and threats to human health, and provides a green and effective means of pest control.
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Figure CN118684723B_ABST