A blood pusher and method

Abstract

The application discloses a blood pushing machine and method. The blood pushing machine comprises a pushing device, an image processing device and a dyeing device. The pushing device is used for pushing and processing a sample to be detected on a blood smear to form a blood film sample on the blood smear. The image processing device is used for acquiring a detection image of the blood film sample and determining whether the blood smear meets a qualified condition based on the detection image. The dyeing device is used for dyeing and processing the blood film sample on the blood smear meeting the qualified condition. Through the above implementation, whether the blood smear meets the qualified condition is determined based on the detection image, and then the dyeing device only dyes and processes the blood film sample meeting the qualified condition, so that the quality of the blood film is greatly improved, and the problem of low microscopic examination efficiency caused by unqualified smears is solved.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical devices, in particular to a blood pushing machine and method. BACKGROUND

[0002] Blood cell counting and blood morphology examination are the most basic and most commonly used tests in blood tests. Blood cell morphology examination is the basis and core of laboratory medicine and an important means of disease diagnosis. At present, blood cell counting has been freed from traditional manual operation and microscopic examination, and can be completed by an automatic blood analyzer.

[0003] Although blood cell analyzers have been popularized and have played a great role in actual work: improving work efficiency and test quality, and providing more scientific parameters for clinical tests. However, blood cell analyzers still do not have the ability to identify the morphology of red blood cells, white blood cells and platelets, and cannot completely replace the identification and classification examination of blood cells by a microscope.

[0004] After the blood smear is processed by the pushing machine, the blood smear needs to be dyed. However, the blood smear processed by the pushing machine may not meet the relevant requirements. At this time, if the dyeing operation is performed on all blood smears after pushing, the quality of the formed blood film sample will be seriously affected, and the microscopic examination efficiency will be low. SUMMARY

[0005] In order to solve the above technical problems in the prior art, the present application provides a blood pushing machine and method.

[0006] To solve the above problems, the present application provides a blood pushing machine, which comprises a pushing device, an image processing device and a dyeing device. The pushing device is used to process a to-be-tested sample on a blood smear to form a blood film sample on the blood smear. The image processing device is used to acquire a detection image of the blood film sample and determine whether the blood smear meets the qualified condition based on the detection image. The dyeing device is used to dye the blood film sample on the blood smear that meets the qualified condition.

[0007] To solve the above problems, the present application provides a blood pushing method, which is applied to the blood pushing machine. The blood pushing method comprises the following steps: the pushing device processes a to-be-tested sample on a blood smear to form a blood film sample on the blood smear; the image processing device acquires a detection image of the blood film sample and determines whether the blood smear meets the qualified condition based on the detection image; and the dyeing device dyes the blood film sample on the blood smear that meets the qualified condition.

[0008] Compared with existing technologies, the blood smear applicator of this application includes a smear-pushing device, an image processing device, and a staining device. The smear-pushing device is used to push the sample to be tested on the blood smear to form a blood film sample on the blood smear. The image processing device is used to acquire a detection image of the blood film sample and determine whether the blood smear meets the qualification criteria based on the detection image. The staining device is used to stain the blood film samples on the blood smears that meet the qualification criteria. Through the above implementation method, the qualification criteria of the blood smear are first determined based on the detection image, and then the staining device only stains the blood film samples that meet the qualification criteria, which can greatly improve the quality of the blood smear and save the problem of low microscopic examination efficiency caused by unqualified smears.

[0009] It should be understood that the above general description and the following detailed description are exemplary and explanatory only, and are not intended to limit this application. Attached Figure Description

[0010] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0011] Figure 1 This is a schematic block diagram of an embodiment of the blood smear machine provided in this application;

[0012] Figure 2 This is a schematic diagram of an embodiment of forming a blood film sample on a blood smear provided in this application;

[0013] Figure 3 This is a schematic diagram of the structure of an embodiment of the blood membrane sample provided in this application;

[0014] Figure 4 This is a schematic diagram of an embodiment of placing a blood smear on a contrast plate provided in this application.

[0015] Reference numerals: Blood smear machine 10; Smear device 100; Image processing device 200; Staining device 300; Light source device 400; Drying device 500; Sample injection device 600; Contrast plate 700; Blood smear 20; Blood film sample 30; First region 31; Second region 32; Third region 33. Detailed Implementation

[0016] The application will be described in further detail below with reference to the drawings and embodiments. It is particularly pointed out that the following embodiments are merely for illustration of the application and do not limit the scope of the application. Similarly, the following embodiments are only part of the embodiments of the application, and all other embodiments obtained by those of ordinary skill in the art without creative work fall within the scope of the application.

[0017] Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the application. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are they necessarily mutually exclusive of other embodiments. It is explicitly contemplated that embodiments described herein can be combined with other embodiments in combinations that are not explicitly stated nor inherently opposed.

[0018] In the description of the application, it should be noted that, unless otherwise explicitly specified and limited, the terms "mounting", "setting", "connecting", "connecting" should be understood broadly, for example, it can be fixedly connected, it can be detachably connected, or integrally connected; it can be mechanically connected, or electrically connected; it can be directly connected, or connected through an intermediate medium. For those of ordinary skill in the art, the above can be connected according to the specific meaning in the application.

[0019] Blood cell count and blood morphology examination is the most basic and most commonly used test in blood test. Blood cell morphology test is the basis and core of laboratory medicine, and is an important means for disease diagnosis. At present, blood cell count has got rid of the traditional manual operation and microscopic examination, which can be completed by automatic blood analyzer.

[0020] Although blood cell analyzer has been popularized and plays a great role in actual work: improving work efficiency and test quality, and providing more scientific parameters for clinical test. Blood cell analyzer still does not have the ability to identify the morphology of red blood cells, white blood cells and platelets, and cannot completely replace the identification and classification examination of blood cells by microscope.

[0021] Observing pathological changes of cell morphology by microscope provides basis for disease diagnosis, which is still an important standard in diagnosis of many diseases. The observation of cell morphology generally includes two steps, i.e. preparation of blood smear and observation of blood smear. Qualified and standard blood smear is the primary condition for normal analysis of blood cell morphology. A good blood smear generally has the following characteristics: clear thickness, clear head-body-tail; uniform cell distribution; neat edge with gap on both sides.

[0022] The blood smear preparation generally has a manual push method and an automatic smear method. The manual push method is applied earlier and is a commonly used method in clinical medicine. However, this method also has the characteristics of low smear production efficiency and poor consistency. The automatic smear method is to realize the automatic sending of the smear, the taking of blood, the pushing of the smear, the marking and the staining of the blood smear by developing a special medical equipment. However, no matter the manual push method or the automatic smear method, it is difficult to absolutely guarantee the smear quality. The manual push method can only rely on manual judgment of the quality of the blood smear. The automatic smear method can only find out whether the smear is normal when the smear is completed and the smear is read. No matter the manual push method or the automatic push method, in the processing of unqualified blood smears, they have the disadvantages of low efficiency and slow response.

[0023] Based on the above technical basis, the application provides a blood smear pushing machine, referring to Figure 1 and Figure 2 , Figure 1 is an embodiment structure schematic diagram of the blood smear pushing machine provided by the application, Figure 2 is an embodiment structure schematic diagram of the blood smear pushing machine provided by the application.

[0024] The blood smear pushing machine 10 comprises a smear pushing device 100, an image processing device 200 and a staining device 300.

[0025] The smear pushing device 100 is used for pushing the sample to be tested on the blood smear 20 to form a blood film sample 30 on the blood smear 20. The blood smear 20 can carry a sample to be tested, which can be a blood sample or a body fluid sample, etc. In this embodiment, the sample to be tested is taken as a blood sample. After the sample to be tested is in the preset position of the blood smear 20, the smear pushing device 100 can start the smear pushing process. Specifically, the smear pushing device 100 can push the sample to be tested according to the preset smear pushing parameters to form a blood film sample 30.

[0026] The image processing device 200 is configured to acquire a detection image of the blood film sample 30, and determine whether the blood smear 20 meets the qualified condition based on the detection image. The image processing device 200 at least includes an image acquisition module and an image analysis module. The image acquisition module can be used to acquire an image of the blood film sample 30 to obtain the detection image of the blood film sample 30. For example, the image acquisition module can be a camera or a camera, etc. The image processing device 200 can also move the image acquisition module to facilitate the image acquisition module to clearly and completely capture the detection image of the blood film sample 30. The image analysis module is configured to receive the detection image and perform an analysis operation on the image to determine the difference between the detection image and the standard image of the blood film sample 30, so as to determine whether the detection image meets the requirements, and further determine whether the blood smear 20 meets the qualified condition. The qualified condition can include that after the blood film sample 30 is used for staining and other operations, the microscopic operation of the blood smear 20 is not affected, etc. After it is determined based on the detection image that the blood smear 20 does not meet the qualified condition, the blood smear 20 can be determined as a discarded blood smear 20 or a pending blood smear 20, and the blood smear 20 is replaced to re-perform the pushing operation. After it is determined based on the detection image that the blood smear 20 meets the qualified condition, subsequent operations can be continued, for example, the blood film sample 30 can be subjected to a staining operation, etc.

[0027] The staining device 300 is configured to perform staining processing on the blood film sample 30 on the blood smear 20 that meets the qualified condition. Specifically, the staining device 300 can perform staining processing on the blood film sample 30 on the blood smear 20 according to a preset staining parameter or a preset staining mode. The preset staining parameter can be a parameter corresponding to the characteristics of the sample to be tested, or can be a parameter corresponding to different staining modes, so that other devices can analyze the blood smear 20, for example, detect the staining quality, perform a microscopic operation on the stained blood smear 20 to obtain a detection result, etc.

[0028] Through the above implementation, it is determined based on the detection image whether the blood smear 20 meets the qualified condition, and then the staining device 300 only performs staining processing on the blood film sample 30 that meets the qualified condition, which can greatly improve the quality of the blood smear 20, and save the problem of low microscopic efficiency caused by unqualified smears.

[0029] In order to detect whether the blood smear 20 meets the qualified condition, whether the blood film sample 30 has an obvious thickness area division can be detected. Referring to Figures 1-3 , Figure 3 is an embodiment structure schematic diagram of the blood film sample 30 provided by the present application.

[0030] The image processing device 200 is configured to determine whether the blood film sample 30 has the first region 31, the second region 32 and the third region 33 based on the detection image, so as to determine whether the blood smear 20 meets the qualified condition, wherein the first region 31, the second region 32 and the third region 33 are arranged in sequence along a pushing direction of the sample to be detected when the pushing device 100 performs the pushing processing on the sample to be detected, and the thickness of the third region 33 is greater than the thickness of the second region 32, and the thickness of the second region 32 is greater than the thickness of the first region 31. During the process of forming the blood film sample 30 by using the pushing device 100, the pushing device 100 moves along the pushing direction to perform the pushing processing on the sample to be detected, and after the pushing is completed, the blood film sample 30 is formed on the blood smear 20. In general, the normal blood film sample 30 includes three regions arranged in sequence along the pushing direction, i.e., the first region 31 with the greatest thickness, the second region 32 with the second greatest thickness, and the third region 33 with the thinnest thickness. Therefore, in the embodiment, whether the blood film sample 30 has obvious first region 31, second region 32 and third region 33 can be detected, and whether the thickness of the blood film sample 30 is clear can be determined. When the thickness of the blood film sample 30 is clear (i.e., the first region 31, the second region 32 and the third region 33 are obvious), it can be determined that the blood smear 20 meets the qualified condition. When the thickness of the blood film sample 30 is not clear (i.e., the first region 31, the second region 32 and the third region 33 are not obvious), it can be determined that the blood smear 20 does not meet the qualified condition.

[0031] In the embodiment, the blood smear 20 has three regions as an example, and whether the thickness of the blood smear 20 is clear can be determined by detecting whether the three regions exist. In other embodiments, the standard blood smear 20 can only include two regions with different thicknesses, and thus, whether the blood smear 20 is qualified can be determined by detecting whether the thicknesses of the two regions are obviously different.

[0032] Further, the image processing device 200 is configured to compare the image of the first region 31, the image of the second region 32 and the image of the third region 33 with the corresponding standard image respectively, to obtain the first similarity between the image of the first region 31 and the corresponding standard image, the second similarity between the image of the second region 32 and the corresponding standard image, and the third similarity between the image of the third region 33 and the corresponding standard image. In this way, the three regions are compared with the standard image respectively to obtain the similarity of each region, so as to determine whether the blood smear 20 meets the qualified condition. The similarity can be determined by detecting whether the shape, texture and other features of the three regions meet the preset condition, so as to determine whether the blood smear 20 is qualified. Taking the shape of the three regions as an example, the standard first region 31 and the second region 32 are square, and the third region 33 is semicircular or semi-elliptical. In this way, the shape of the first region 31 divided from the blood film sample 30 and the standard first region 31 is compared, to obtain the first similarity between the image of the first region 31 and the corresponding standard image; the shape of the second region 32 divided from the blood film sample 30 and the standard second region 32 is compared, to obtain the second similarity between the image of the second region 32 and the corresponding standard image; and the shape of the third region 33 divided from the blood film sample 30 and the standard third region 33 is compared, to obtain the third similarity between the image of the third region 33 and the corresponding standard image. In other embodiments, other features or combinations of multiple features in each region can be compared with the corresponding features in the standard image to obtain the respective similarity, which can be similar to the similarity of the shape detected above, and will not be described herein.

[0033] After the similarity of each region is determined, whether the blood smear 20 meets the qualified condition can be determined based on the similarity. Specifically, the image processing apparatus 200 is further configured to determine whether the first region 31 meets a first similarity condition based on the first similarity, to determine whether the second region 32 meets a second similarity condition based on the second similarity, and to determine whether the third region 33 meets a third similarity condition based on the third similarity, to determine whether the blood smear 20 meets the qualified condition. Specifically, the first similarity can be compared with a first similarity threshold, when the first similarity is greater than or equal to the first similarity threshold, it can be determined that the first region 31 meets the first similarity condition; the second similarity can be compared with a second similarity threshold, when the second similarity is greater than or equal to the second similarity threshold, it can be determined that the second region 32 meets the second similarity condition; the third similarity can be compared with a third similarity threshold, when the third similarity is greater than or equal to the third similarity threshold, it can be determined that the third region 33 meets the third similarity condition. Wherein the first similarity threshold, the second similarity threshold and the third similarity threshold can be set according to the actual situation. Thus, by determining the similarity of different regions to the standard image, the difference between the blood film sample 30 and the standard image can be further determined, so as to more accurately identify whether the blood smear 20 meets the qualified condition.

[0034] Optionally, the image processing apparatus 200 is configured to compare the brightness uniformity of the first region 31 image with a first brightness threshold, and determine whether the first region 31 meets a first brightness condition based on the comparison result; the image processing apparatus 200 is configured to compare the brightness uniformity of the second region 32 image with a second brightness threshold, and determine whether the second region 32 meets a second brightness condition based on the comparison result; the image processing apparatus 200 is configured to compare the brightness uniformity of the third region 33 image with a third brightness threshold, and determine whether the third region 33 meets a third brightness condition based on the comparison result, to determine whether the blood smear 20 meets the qualified condition. In an application scenario, when the image processing apparatus 200 acquires the detection image, the light source is used to continuously emit illumination light to the blood film sample 30, so as to improve the brightness of the blood film sample 30. When the blood cells in each region are uniformly distributed, the uniformity of each position of the illuminated blood film sample 30 is higher, that is, the difference between the brightness and darkness in the same region is small. Based on this, when the blood cells in each region are uniformly distributed, the brightness uniformity of the corresponding detection image in the same region is higher; otherwise, the brightness uniformity in the same region is lower. After determining the brightness uniformity of each region, the brightness uniformity of each region can be compared with the brightness threshold of each region, so as to determine whether the brightness uniformity of each region meets the condition, to further determine whether the blood smear 20 meets the qualified condition. The first brightness threshold, the second brightness threshold, the third brightness threshold, the first brightness condition, the second brightness condition and the third brightness condition can be set according to actual conditions, for example, the first brightness condition can include that the brightness uniformity of the first region 31 image is greater than or equal to the first brightness threshold; the second brightness condition can include that the brightness uniformity of the second region 32 image is greater than or equal to the second brightness threshold; and the third brightness condition can include that the brightness uniformity of the third region 33 image is greater than or equal to the third brightness threshold. In this way, the uniformity of the cell distribution in the blood film sample 30 can be further determined, so that whether the blood smear 20 meets the qualified condition can be more quickly and accurately identified.

[0035] In an embodiment, the image processing device 200 is configured to detect whether the edge line of the detection image meets a preset straightness condition to determine whether the blood smear 20 meets the qualified condition. The edge line of the detection image can be regarded as the outer contour of the blood film sample 30. When the outer contour of the blood film sample 30 is relatively straight, the straightness of the edge line of the detection image is higher. For example, when the blood film sample 30 includes the first region 31, the second region 32 and the third region 33, whether a certain edge contour line of the first region 31 and the second region 32 is a straight line extending in the direction of the pusher. When the certain edge contour line of the first region 31 and the second region 32 is a straight line extending in the direction of the pusher, it can be determined that the blood smear 20 meets the qualified condition. Otherwise, when the certain edge contour line of the first region 31 and the second region 32 is a plurality of spaced line segments, it is considered that the blood smear 20 does not meet the qualified condition. Thus, it can be more quickly and accurately determined whether the blood smear 20 meets the qualified condition.

[0036] In an embodiment, the image processing device 200 is configured to detect whether there is a gap in the detection image to determine whether the blood smear 20 meets the qualified condition. The gap can exist in the middle region of the detection image, or the gap can intersect with the outer edge line of the detection image. The gap can have different shapes, such as a circular shape, a square shape, etc. In this embodiment, when it is detected that there is a gap in the detection image, it can be determined that the blood smear 20 does not meet the qualified condition. Otherwise, it is considered that the blood smear 20 meets the qualified condition. Thus, it can be more quickly and accurately determined whether the blood smear 20 meets the qualified condition.

[0037] Referring to Figures 1-4 , Figure 4 is an embodiment structure schematic diagram of placing the blood smear 20 on the contrast base plate 700 provided by the present application.

[0038] The blood pusher 10 further includes a contrast base plate 700 and a light source device 400. The contrast base plate 700 is located between the light source device 400 and the image processing device 200. The blood smear 20 is arranged on the side of the contrast base plate 700 facing the image processing device 200. The light source device 400 is configured to emit illumination light to the contrast base plate 700. The contrast base plate 700 is configured to improve the contrast of the detection image. The blood smear 20 can be a transparent glass or quartz sheet. The contrast base plate 700 can be provided with a relatively high contrast. The blood smear 20 faces the image processing device 200, and the contrast base plate 700 faces the light source device 400. When the contrast base plate 700 receives the illumination and transmits to the blood film sample 30, the contrast of the detection image can be improved, so that the subsequent analysis and processing of the detection image can be facilitated. Thus, the accuracy of recognizing the detection image can be improved, and the accuracy of determining whether the blood smear 20 is qualified can be further improved.

[0039] In an embodiment, the blood slide pushing machine 10 further comprises a drying device 500 for drying the blood film sample 30 before or after the image processing device 200 collects the detection image. The drying device 500 can dry the blood film sample 30, so that the morphology of the blood film sample 30 can be stabilized, and the dried blood film sample 30 can also be detected for drying, so as to determine the drying effect of the blood film sample 30. In this embodiment, the drying step can be after or before the image collection. When the drying step can be before the image collection, a more accurate detection image can be obtained, and the accuracy of the result can be improved. When the drying step can be after the image collection, the problem of low microscopic examination efficiency caused by unqualified smears can be saved.

[0040] In an embodiment, the blood slide pushing machine 10 further comprises a sample feeding device 600 for transporting the sample to be tested to the blood smear 20. The sample feeding device 600 is mainly responsible for sampling the sample to be tested and transporting the sampled sample to be tested to the blood smear 20. For example, the sample feeding device 600 can include a sampling needle. The sampling needle is immersed in the sample to be tested to suck the sample to be tested, and then the sampling needle is controlled to move above the blood smear 20 to drop the sample to be tested on the blood smear 20 to form a sample feeding operation of the sample to be tested.

[0041] In some embodiments, the blood slide pushing machine 10 further comprises a cleaning device. After the pushing device 100 completes the pushing, the pushing device 100 can be cleaned by the cleaning device.

[0042] Through the above-mentioned embodiments, whether the blood smear 20 meets the qualified condition is determined based on the detection image, and then the staining device 300 only stains the blood film sample 30 that meets the qualified condition, which can greatly improve the quality of the blood smear 20 and save the problem of low microscopic examination efficiency caused by unqualified smears.

[0043] To solve the technical problems in the prior art, the application further provides a blood slide pushing method. The blood slide pushing method is applied to the blood slide pushing machine 10 in any of the above-mentioned embodiments. The blood slide pushing method comprises the following steps:

[0044] The pushing device 100 pushes the sample to be tested on the blood smear 20 to form a blood film sample 30 on the blood smear 20. The image processing device 200 acquires a detection image of the blood film sample 30 and determines whether the blood smear 20 meets the qualified condition based on the detection image. The staining device 300 stains the blood film sample 30 on the blood smear 20 that meets the qualified condition. The blood slide pushing method can be realized by a control device, that is, the control device controls each device to realize the corresponding function, and finally realizes the blood slide pushing method.

[0045] Through the above-mentioned embodiments, whether the blood smear 20 meets the qualified condition is determined based on the detection image first, and then the staining device 300 only performs the staining process on the blood film sample 30 meeting the qualified condition, which can greatly improve the quality of the blood smear 20 and save the problem of low microscopic efficiency caused by unqualified smears.

[0046] In addition, when the above functions are implemented in the form of software functions and sold or used as independent products, they can be stored in a mobile terminal readable storage medium, that is, the application also provides a storage device storing program data, which can be executed to implement the method of the above-mentioned embodiments. The storage device can be, for example, a U disk, an optical disk, a server, etc. That is, the application can be embodied in the form of a software product, which includes a plurality of instructions for causing an intelligent terminal to execute all or part of the steps of the method described in each embodiment.

[0047] In the description of the present application, the description of the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" means that the specific features, structures, materials or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the present application. In the present specification, the illustrative description of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any appropriate manner in any one or more embodiments or examples. In addition, the skilled person in the art can combine and combine the different embodiments or examples described in the specification and the features of the different embodiments or examples without contradiction.

[0048] In addition, the terms "first", "second" are only for descriptive purposes and cannot be understood as indicating or implying relative importance or implicitly indicating the number of indicated technical features. Therefore, the features defined with "first", "second" can explicitly or implicitly include at least one of the features. In the description of the present application, the meaning of "multiple" is at least two, for example, two, three, etc., unless otherwise explicitly specified.

[0049] Any process or method descriptions in flow charts or otherwise described herein can be understood as representing code modules, segments, or portions of code that include one or more executable instructions for implementing specific logic functions or other processes, and the various preferred embodiments of the application include additional implementations in which the order of execution is different, in which other code modules are utilized, in which not all code modules are utilized, in which code modules are utilized in combination with one another, and in which other structures and methods of implementation are utilized.

[0050] The logic and / or steps represented in the flow diagrams and / or otherwise described herein, for example, can be embodied in non-transitory computer-readable media, executed by an instruction execution system, apparatus, or device, such as a personal computer, server, network device, or other computing / processing apparatuses that can fetch the instructions from the instruction execution system, apparatus, or device and execute the instructions. In this regard, the "computer-readable medium" can be any apparatus that can contain, store, communicate, propagate, or transport the program for use by or in connection with the instruction execution system, apparatus, or device. The computer-readable medium can comprise any one of the following: electric connections (electronic devices), a portable computer diskette (magnetic devices), a random access memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or Flash memory), an optical fiber, and a portable compact disc read-only memory (CDROM). Additionally, the computer-readable medium can even be paper or other suitable medium upon which the program is printed, as the program can be electronically captured, via for instance an optical scanner, then compiled, interpreted, or otherwise processed, and stored in a computer storage medium.

[0051] The above description is merely illustrative of the embodiments of this application and is not intended to limit the scope of the application. Any equivalent structure or equivalent processes variant using the content of the specification and the drawings of this application, or directly or indirectly applied in other related technical fields, are also included in the patent protection scope of this application.

Claims

1. A blood pusher, characterized by, The method comprises the following steps: A pushing device is used to push the sample on a blood smear to form a blood film sample on the blood smear; An image processing device is used to acquire a detection image of the blood film sample and determine whether the blood smear meets the qualified condition based on the detection image; A staining device is used to stain the blood film sample on the blood smear meeting the qualified condition; The image processing device is used to determine whether the blood film sample has a first area, a second area and a third area based on the detection image, so as to determine whether the blood smear meets the qualified condition, wherein the first area, the second area and the third area are arranged in sequence along the pushing direction of the pushing device when the pushing device pushes the sample, the thickness of the third area is greater than that of the second area, and the thickness of the second area is greater than that of the first area, the blood film sample is detected by detecting whether the first area, the second area and the third area are obvious, and when the blood film sample is clear in thickness, it is determined that the blood smear meets the qualified condition.

2. The blood pusher according to claim 1, wherein The image processing device is used to compare the image of the first area, the image of the second area and the image of the third area with the corresponding standard image respectively, so as to obtain the first similarity between the image of the first area and the corresponding standard image, the second similarity between the image of the second area and the corresponding standard image, and the third similarity between the image of the third area and the corresponding standard image. The image processing device is also used to determine whether the first area meets the first similarity condition based on the first similarity, whether the second area meets the second similarity condition based on the second similarity, and whether the third area meets the third similarity condition based on the third similarity, so as to determine whether the blood smear meets the qualified condition.

3. The blood pusher according to claim 1, wherein The image processing device is used to compare the brightness uniformity of the first area image with a first brightness threshold, and determine whether the first area meets the first brightness condition based on the comparison result; The image processing device is used to compare the brightness uniformity of the second area image with a second brightness threshold, and determine whether the second area meets the second brightness condition based on the comparison result; The image processing device is used to compare the brightness uniformity of the third area image with a third brightness threshold, and determine whether the third area meets the third brightness condition based on the comparison result, so as to determine whether the blood smear meets the qualified condition.

4. The blood pusher according to claim 1, wherein The image processing device is used to detect whether the edge line of the detection image meets a preset alignment condition, so as to determine whether the blood smear meets the qualified condition.

5. The blood pusher according to claim 1, wherein The image processing device is used to detect whether there is a gap in the detection image, so as to determine whether the blood smear meets the qualified condition.

6. The blood pusher according to any one of claims 1 to 5, wherein The blood smearing machine further comprises a contrast base plate and a light source device, the contrast base plate is located between the light source device and the image processing device, the blood smear is arranged on one side of the contrast base plate facing the image processing device, the light source device is used for emitting illumination light to the contrast base plate, and the contrast base plate is used for improving the contrast of the detection image.

7. The blood pusher according to any one of claims 1 to 5, wherein The blood smearing machine further comprises a drying device, which is used for drying the blood film sample before or after the image processing device collects the detection image.

8. The blood pusher according to any one of claims 1 to 5, wherein The blood smearing machine further comprises a sample feeding device, which is used for transporting the to-be-tested sample to the blood smear.

9. A method of blood pushing, characterized by, The blood smearing method is applied to the blood smearing machine as claimed in any one of claims 1-8, and the method comprises: the smearing device performing smearing processing on the to-be-tested sample on the blood smear to form a blood film sample on the blood smear; The image processing device acquires a detection image of the blood film sample, and determines whether the blood smear meets the qualified condition based on the detection image; The staining device performs staining processing on the blood film sample on the blood smear meeting the qualified condition. The blood smearing machine further comprises a contrast base plate and a light source device, the contrast base plate is located between the light source device and the image processing device, the blood smear is arranged on one side of the contrast base plate facing the image processing device, the light source device is used for emitting illumination light to the contrast base plate, and the contrast base plate is used for improving the contrast of the detection image. The blood smearing machine further comprises a drying device, which is used for drying the blood film sample before or after the image processing device collects the detection image. The blood smearing machine further comprises a sample feeding device, which is used for transporting the to-be-tested sample to the blood smear. The blood smearing method is applied to the blood smearing machine as claimed in any one of claims 1-8, and the method comprises: the smearing device performing smearing processing on the to-be-tested sample on the blood smear to form a blood film sample on the blood smear; The image processing device acquires a detection image of the blood film sample, and determines whether the blood smear meets the qualified condition based on the detection image; The staining device performs staining processing on the blood film sample on the blood smear meeting the qualified condition.

Images