An artificial cornea implanted once imitating the human eye and its usage method

Abstract

The present invention discloses a humanoid eye-mimicking artificial cornea for single implantation, belonging to the technical field of in-vivo prosthesis implantation. It solves at least the problem that the existing artificial corneas cannot simulate the appearance of real eyes. The artificial cornea includes a lens column, a stent and a cosmetic disc; wherein, the lens column includes a lens column body and a rear disc coaxially arranged at a position close to the rear end face of the lens column body; the cosmetic disc is coaxially arranged at the front end of the lens column body; the stent is coaxially and movably arranged on the lens column body between the rear disc and the cosmetic disc; in the use state, the stent and the rear disc clamp the cornea one in front and the other behind; the cosmetic disc has a central opening and has an iris texture area and a sclera texture area; an iris texture layer is formed in the iris texture area, and a mimic conjunctival vascular texture layer is formed in the sclera texture area. The present invention also provides a method for using the humanoid eye-mimicking artificial cornea for single implantation.

Description

Technical Field

[0001] The present invention belongs to the technical field of in - vivo prosthesis implantation, and particularly relates to an artificial cornea for one - time implantation imitating the human eye and its usage method. Background Art

[0002] An artificial cornea refers to a special refractive device made of artificial materials, which is used to replace the cloudy cornea that hinders the optical path of the eyeball after disease, so that the patient can obtain a certain vision.

[0003] Iris patterns are determined by genetic genes, and each person's iris pattern is unique and has a stable physiological structure. These texture features include shapes such as radial stripes, dots, filaments, coronas, crypts, etc. Placing a beauty sheet with an iris texture pattern on the eye surface of a patient is mainly to simulate the appearance of a real eye. However, the artificial corneas provided by the existing technologies only have the refractive function and do not simulate the appearance of a real eye. The artificial corneas provided by the existing technologies are prone to postoperative complications such as anterior membrane of the artificial cornea.

[0004] In view of this, there is an urgent need to propose an artificial cornea for one - time implantation imitating the human eye and its usage method. Summary of the Invention

[0005] The purpose of the present invention is to provide an artificial cornea for one - time implantation imitating the human eye and its usage method, so as to simulate the appearance of a real eye and reduce postoperative complications such as anterior membrane.

[0006] To achieve the above purpose, the present invention provides the following technical solutions:

[0007] In a first aspect, the present invention provides an artificial cornea for one - time implantation imitating the human eye, which includes a lens column, a stent, and a beauty disc; wherein, the lens column includes a lens column body and a rear disc coaxially arranged at a position close to the rear end face of the lens column body; the beauty disc is coaxially arranged at the front end of the lens column body; the stent is coaxially and movably arranged on the lens column body between the rear disc and the beauty disc; in the use state, the stent and the rear disc clamp the cornea front and back; the beauty disc has a central opening and has an iris texture area and a scleral texture area; an iris texture layer is formed in the iris texture area, and an artificial conjunctival vascular texture layer imitating the sclera is formed in the scleral texture area.

[0008] As a possible implementation manner, the iris texture layer and the artificial conjunctival vascular texture layer imitating the sclera are formed by using image processing and 3D printing.

[0009] As a possible implementation manner, the iris texture layer and the artificial conjunctival vascular texture layer imitating the sclera are any one of a corneal contact lens, a contact lens, an iris covering sheet, or colored contact lenses attached to the beauty disc.

[0010] As a possible implementation manner, the beauty disc is oval, with a major axis of 11 mm to 26 mm and a minor axis of 5.5 mm to 11 mm.

[0011] As a possible implementation, the radius of curvature of the beauty disc is 12 mm ± 3.0 mm.

[0012] As a possible implementation, the beauty disc has a structure that is thicker in the middle and thinner at both sides, is made of resin, and the maximum thickness is 0.05 - 0.5 mm.

[0013] As a possible implementation, the beauty disc is a resin beauty disc, and a notch for easy clamping is provided at the edge of the resin beauty disc.

[0014] As a possible implementation, the beauty disc is a resin beauty disc, an external thread is provided at the position of the lens column body for installing the beauty disc, and the diameter is smaller than that of other positions to form a limiting step; an internal thread corresponding to it is provided on the inner wall of the central hole of the beauty disc.

[0015] As a possible implementation, the beauty disc is made of silicone hydrogel, hydrogel ionic material, or non - ionic material and is sleeved on the front end of the lens column body.

[0016] As a possible implementation, the front end face of the lens column body is flush with or protrudes from the central opening of the beauty disc.

[0017] In a second aspect, the present invention also provides a method for using an artificial cornea implanted into a human - like eye at one time, including the following steps:

[0018] S10. Insert the rear end of the artificial cornea lens column together with the rear disc into the anterior chamber.

[0019] S11. Slide the rear disc of the stent to the posterior surface of the cornea so that the lens column is located at the center of the corneal drill hole.

[0020] S12. Suture the radial side incisions of the cornea until they are watertight.

[0021] S13. Rotate the stent until it fits the anterior surface of the cornea.

[0022] S14. Suture and fix the stent on the anterior surface of the cornea. At this time, the rear disc and the stent clamp the cornea front and back.

[0023] S15. Reinforce the stent with biological tissue or synthetic materials.

[0024] Compared with the prior art, the present invention has the following effects:

[0025] 1. A beauty disc is added to the artificial cornea, and a central opening is provided on the beauty disc. The beauty disc has an iris texture area of the same size as the cornea. On the one hand, it does not affect the refractive function that the artificial cornea must possess. On the other hand, an iris texture layer and a scleral texture layer are formed in the iris texture area, which can simulate the appearance of a real eye.

[0026] 2. The beauty disk of the present invention can prevent biological tissues from growing into the front end surface of the lens column body, reducing the occurrence of complications such as posterior membranes.

[0027] 3. Reduce tear evaporation, reduce the degree of dry eye after surgery, and reduce medication.

[0028] 4. No donor cornea is required, and the treatment of corneal blindness can be completed with a single implantation surgery.

[0029] 5. The stent is located on the outer surface of the cornea, with low surgical difficulty, small trauma, short healing period and good healing effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] The drawings described herein are used to provide a further understanding of the present invention and form a part of the present invention. The schematic embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an improper limitation of the present invention.

[0031] Figure 1 It is a schematic diagram of the overall structure of the artificial cornea provided by the embodiment of the present invention;

[0032] Figure 2 It is a schematic diagram of the structure of the lens column provided by the embodiment of the present invention;

[0033] Figure 3 It is a schematic diagram of the structure of the stent provided by the embodiment of the present invention;

[0034] Figure 4 It is a schematic diagram of the structure of the connection for the stent provided by the embodiment of the present invention;

[0035] Figure 5 It is a schematic diagram of the structure of another stent provided by the embodiment of the present invention.

[0036] Reference Numerals:

[0037] 1 - lens column, 10 - lens column body, 11 - rear disk;

[0038] 2 - stent, 20 - stent body, 21 - connection ring, 210 - internal thread, 211 - annular groove, 212 - notch, 213 - pinhole;

[0039] 3 - beauty disk. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0040] In order to clearly describe the technical solutions of the embodiments of the present invention, in the embodiments of the present invention, words such as "first" and "second" are used to distinguish the same items or similar items with basically the same functions and effects. For example, the first threshold and the second threshold are only used to distinguish different thresholds, and their order is not limited. Those skilled in the art can understand that words such as "first" and "second" do not limit the quantity and execution order, and words such as "first" and "second" do not necessarily limit them to be different.

[0041] It should be noted that, in the present invention, words such as "exemplary" or "for example" are used to indicate examples, illustrations or descriptions. Any embodiment or design described as "exemplary" or "for example" in the present invention should not be interpreted as being more preferred or more advantageous than other embodiments or designs. Specifically, the use of words such as "exemplary" or "for example" is intended to present related concepts in a specific way.

[0042] In the present invention, "at least one" means one or more, and "plurality" means two or more. "And / or" describes the association relationship of associated objects, indicating that three relationships may exist. For example, A and / or B can mean: A exists alone, A and B exist at the same time, and B exists alone, where A and B can be singular or plural. The character " / " generally indicates that the associated objects before and after are in an "or" relationship. "At least one of the following" or similar expressions refers to any combination of these items, including any combination of single or plural items. For example, at least one of a, b or c can mean: a, b, c, the combination of a and b, the combination of a and c, the combination of b and c, or the combination of a, b and c, where a, b, c can be single or multiple.

[0043] See also Figure 1 and Figure 2 The embodiment of the present invention provides a one-time implantable artificial cornea that simulates a human eye, including a lens column 1, a bracket 2, and a cosmetic plate 3. The lens column 1 includes a lens column body 10 and a rear plate 11 coaxially arranged at a position close to the rear end surface of the lens column body 10; the cosmetic plate 3 is coaxially arranged at the front end of the lens column body 10; the bracket 2 is coaxially and movably arranged on the lens column body 10 between the rear plate 11 and the cosmetic plate 3; in the use state, the bracket 2 and the rear plate 11 clamp the cornea in front and back; the cosmetic plate 3 has a central opening and has an iris texture area and a sclera texture area; the iris texture area is formed with an iris texture layer, and the sclera texture area is formed with a texture layer of vascular imitating the bulbar conjunctiva.

[0044] A beauty disc 3 is coaxially arranged at the front end of the lens column 1, and a texture imitating a human eye is formed on the beauty disc 3, making the artificial cornea closer to a real human eye and improving the aesthetics. Moreover, it will not affect the refractive function that the artificial cornea must possess. The beauty disc 3 provided by the embodiment of the present invention can prevent biological tissues from growing into the front end face of the lens column body 10, reduce the occurrence of complications such as posterior membranes, that is, reduce the adverse effects on the diopter of the lens column 1. The beauty disc 3 is equivalent to a barrier on the ocular surface and is placed outside the ocular surface, which can reduce tear evaporation, that is, can reduce the degree of dry eye after surgery and reduce medication.

[0045] The iris texture layer and the texture layer imitating conjunctival blood vessels are formed by applying image processing and 3D printing. That is, image processing technology is applied for feature extraction to generate images of the iris texture layer and the texture layer imitating conjunctival blood vessels. Then 3D printing is applied to form the iris texture layer and the texture layer imitating conjunctival blood vessels in the corresponding areas of the beauty disc 3. For example, high molecular density resin can be formed on the front surface of the beauty disc 3 through spraying or printing processes.

[0046] The iris texture layer and the texture layer imitating conjunctival blood vessels are any one of a corneal contact lens, a contact lens, an iris covering piece, or colored contact lenses attached to the beauty disc 3.

[0047] The size of the beauty disc 3 is adapted to the size of the conjunctival sac. The beauty disc 3 can be a sheet-like structure in the shape of an ellipse with a certain curvature. Its major axis is 11 mm to 26 mm, and its minor axis is 5.5 mm to 11 mm. For example, the major axis is 11 mm and the minor axis is 5.5 mm, or the major axis is 26 mm and the minor axis is 11 mm.

[0048] The radius of curvature of the beauty disc 3 is 12 mm ± 3.0 mm. For example, specifically 9 mm, 10 mm, 11 mm, 12 mm, 13 mm, 14 mm, or 15 mm.

[0049] The beauty disc 3 has a structure that is thicker in the middle and thinner at both sides, is made of resin, and has a thickness of 0.05 to 0.5 mm. For example, the position of the beauty disc 3 close to the central hole is the thickest, and its thickness is 0.05 mm, 0.06 mm, 0.07 mm, 0.08 mm, 0.09 mm, 0.1 mm, 0.2 mm, 0.3 mm, 0.4 mm, or 0.5 mm.

[0050] In order to facilitate the installation of the resin beauty disc and the lens column body 10, a notch (not shown in the figure) for easy clamping can be provided at the edge of the resin beauty disc. The notches can be evenly distributed at intervals along the circumference of the resin beauty disc.

[0051] The beauty disc 3 is a resin beauty disc. An external thread is provided at the position of the lens column body 10 for installing the resin beauty disc, and the diameter is smaller than that of other positions to form a limiting step; an internal thread corresponding to it is provided on the inner wall of the central hole of the beauty disc 3.

[0052] The pitch of the threaded section at the installation position of the resin beauty disc is different from that of the threaded section at the installation position of the bracket, so that the resin beauty disc will not continue to rotate downward after being installed in place. That is, the threaded sections with different pitches can play a limiting role.

[0053] The beauty disc 3 is made of silicone hydrogel, hydrogel ionic material, or non-ionic material and is sleeved on the front end of the lens column body 10. That is, the beauty disc 3 is a non-rigid beauty disc. In other words, the beauty disc 3 has a certain elasticity. The diameter of the central opening of the beauty disc 3 is smaller than the diameter of the lens column body 10 at the position for installing the beauty disc. Using its own elasticity, the beauty disc 3 tightly wraps around the front end of the lens column body 10. This setting not only facilitates assembly but also does not affect the refractive vision field of the lens column body 10.

[0054] The front end face of the lens column body 10 is flush with or protrudes from the central opening of the beauty disc 3 to minimize the adverse effect of the beauty disc 3 on the refractive vision field of the lens column body 10.

[0055] In the assembled state, the bracket 2 and the lens column 1 can be screwed together.

[0056] The lens column body 10 and the rear disc 11 are made of the same material and can be integrally formed, or they can be separately manufactured and then coaxially and firmly connected together by any method after the lens column body 10 and the rear disc 11 are completed.

[0057] The part of the lens column body 10 in front of the rear disc 11 can be a cylindrical structure with the same diameter from top to bottom, and an external threaded section matching the internal thread 210 of the bracket 2 is provided from top to bottom at the position where it is screwed with the bracket 2.

[0058] The diameter of the lens column body 10 is smaller than that of the rear disc 11. Specifically, the diameter of the lens column body 10 is 2.0 - 3.5 mm. The diameter of the rear disc 11 is 2 - 4 mm larger than the diameter of the lens column body 10, that is, the diameter of the rear disc 11 is 4 - 7.5 mm. For example, the diameter of the lens column body 10 is 2 mm and the diameter of the rear disc 11 is 4 mm; the diameter of the lens column body 10 is 3 mm and the diameter of the rear disc 11 is 5 mm; the diameter of the lens column body 10 is 3.5 mm and the diameter of the rear disc 11 is 7.5 mm.

[0059] In practical applications, the corneal diameter is 11 mm and the drilling diameter is 2.5 mm. The diameter of the rear disc 11 is less than or equal to the sum of the corneal radius and the lens column body 10 radius.

[0060] The total length of the lens column body 10 is 4.5 - 8.5 mm, of which the length from the rear disc 11 to the rear end face is 1 - 2 mm, the length of the optical axis section from the rear disc 11 to the end of the threaded section is 0.2 - 0.5 mm, the rear disc 11 is 0.3 - 0.5 mm, and the threaded section is 3 - 5.5 mm.

[0061] The diopter of the lens column 1 is 42 - 62D. For example, 42D, 45D, 50D, 55D, 60D or 62D.

[0062] The side bottom end to the rear end face of the lens column body 10 behind the rear disc 11 is a square edge. With such a setting, it is difficult for the biological tissue around the square edge to grow past the square edge towards the rear end face, that is, it can avoid the continuously growing biological tissue from covering the rear end face of the lens column 1, thus effectively avoiding the problem that the lens column 1 cannot transmit light due to being covered by the continuously growing biological tissue.

[0063] The square edge is one of a right - angled edge, an obtuse - angled edge or an acute - angled edge. The lens column body 10 behind the rear disc 11 is one of a constant - diameter structure, a structure with a gradually decreasing diameter or a structure with a gradually increasing diameter.

[0064] The lens column body 10 behind the rear disc 11 is one of a constant - diameter structure, a structure with a gradually decreasing diameter or a structure with a gradually increasing diameter.

[0065] A hydroxyapatite film layer is coated on the non - threaded section of the lens column body 10. When using atmospheric plasma spraying, the coating thickness is 30 - 150 microns, and the adhesion strength is at least 10 Mpa.

[0066] The lens column body 10 constitutes an optical device for replacing the eye light path, that is, light forms an image on the retina after passing through the lens column body 10.

[0067] An annular outer edge is provided forward on the outer periphery of the rear disc 11 to enclose the rear surface of the rear disc 11 and the corneal surface, preventing water leakage and infection.

[0068] The material of the lens column 1 is at least one of hydroxyethyl polymethacrylate, polymethyl methacrylate, bioceramics or optical glass.

[0069] See Figures 3 to 5 , the bracket 2 can be a metal bracket, such as a medical titanium metal bracket. It can also be a PMMA bracket, that is, the material of the bracket 2 is the same as or similar to the material of the lens column 1.

[0070] When the bracket 2 is a metal bracket, in order to shorten the healing period of the bracket 2 and the cornea and improve the healing effect, a layer of hydroxyapatite can be coated on the surface of the bracket 2.

[0071] When the support 2 is a metal support, the primary implantation of the artificial cornea further includes a connecting ring 21 in the shape of a hollow stepped shaft. The material of the connecting ring 21 is the same as or similar to that of the lens column 1. An internal thread 210 is provided on the inner wall of the connecting ring 21, and an external thread section matching the internal thread 210 is provided on the front section of the lens column 1. A circular groove 211 is provided at the shaft shoulder of the outer wall of the hollow stepped shaft. The inner wall of the central mounting hole of the support 2 is snapped into the circular groove 211 in an interference fit manner; and the connecting ring 21 is snapped into the central mounting hole of the support from front to back.

[0072] When the materials of the support 2 and the lens column 1 are different but relative movement needs to occur in a threaded connection manner, the metal support 2 will damage the threads of the lens column 1. The internal and external thread sections of the same material minimize the damage to each other during rotational movement when relative displacement changes occur between the two. Moreover, since the connecting ring 21 is snapped into the central mounting hole of the support from front to back, when the support 2 is rotated towards the ocular surface during the operation, the connecting ring 21 will not fall off into the eye from the central mounting hole.

[0073] When both the support 2 and the lens column 1 are made of PMMA, the support 2 and the lens column 1 can be directly connected without the above-mentioned connecting ring 21. That is, an internal thread 210 matching the external thread section can be directly provided on the inner wall of the central mounting hole of the support 2.

[0074] Structurally, the support 2 can be a butterfly support, a single-ring support, a double-ring support (with grid connecting pieces between the outer ring and the inner ring), or a mesh support. Among them, the mesh support facilitates the nutritional exchange between the anterior and posterior tissues.

[0075] Since the support 2 needs to fit the anterior surface of the cornea, it needs to have a certain curvature to ensure that the support 2 can completely fit on the anterior surface of the cornea. Moreover, the support 2 needs to have a certain rigidity, that is, after the support 2 is attached to the anterior surface of the cornea, it is not easily deformed or warped by force. The support 2 also needs to have a certain flexibility. Since the corneal curvatures of different patients vary, the support 2 with a certain flexibility can have a certain deformation space to adapt to corneas with different curvatures.

[0076] The support 2 is provided with a notch 212 or a pinhole 213 for convenient suture fixation. With such a setting, it is convenient to suture and fix the support 2 on the ocular surface. After the radial side incisions of the cornea are sutured, the human cornea is fixed on the posterior surface of the cornea. After the support 2 is moved to fit the anterior surface of the cornea, the support 2 is then sutured to the cornea using the notch 212 or the pinhole 213.

[0077] Outside the cornea, biological tissue or synthetic material is also sutured to reinforce the stent 2. The biological tissue covers the stent 2 and surrounds the lens column 1, serving to reinforce both the stent 2 and the lens column 1 simultaneously. The tissue is, in order from posterior to anterior, auricular cartilage, Tenon's capsule, and epithelial tissue. The synthetic material can be hydroxyapatite or artificial bone.

[0078] In specific applications, the patient's own auricular cartilage can be taken, drilled at the position corresponding to the lens column 1, and sutured to the cornea to surround the lens column 1 and cover the stent 2. This achieves secondary reinforcement of the artificial cornea, making the artificial cornea more stable and less prone to dislocation. Additionally, after the cornea is covered by auricular cartilage, it is equivalent to having a barrier on it, which not only plays a protective role but also can prevent corneal dissolution.

[0079] On the anterior surface of the auricular cartilage, Tenon's capsule is further covered. It belongs to the biological capsule on the ocular surface and has a certain flexibility and elasticity. Using Tenon's capsule can achieve tertiary reinforcement of the artificial cornea.

[0080] The outer peripheral dimension of the stent 2 is 8.5 mm to 10 mm. For example, the outer peripheral dimension of the stent 2 is 8.5 mm, 9.0 mm, 9.5 mm, or 10 mm.

[0081] The radius of curvature of the stent 2 is 7.8 mm ± 2.0 mm. For example, the radius of curvature of the stent 2 is 5.8 mm, 6.8 mm, 7.8 mm, 8.8 mm, or 9.8 mm.

[0082] The artificial cornea provided by the present invention is implanted into the eye of a severely corneal blind patient in the following manner to achieve the purpose of restoration of vision. That is, a trephine is used to punch a hole in the center of the patient's cornea, and a radial side incision of the cornea is made on one side of the hole to improve the surgical field of view, facilitate the complete removal of the lens, or solve the problem of residual lens cortex existing in the prior art.

[0083] After removing the lens and excising the anterior vitreous, the posterior disc 11 included in the artificial cornea is implanted into the above-mentioned drilled hole, that is, the posterior disc 11 enters the cornea through the radial side incision of the cornea and fits with its posterior surface. At this time, the radial side incision of the cornea can be sutured to preliminarily fix the lens column 1. On this basis, the stent 2 is rotated to move the stent 2 backward. When the stent 2 fits with the anterior surface of the cornea, the stent 2 and the posterior disc 11 clamp the cornea from front and back, and the stent 2 is sutured to the cornea to fix the stent 2 on the ocular surface.

[0084] As can be seen from the above application process, the artificial cornea provided by the present invention only requires one surgery to complete the treatment of corneal blindness, shortening the surgical period, and can reduce the anxiety of patients waiting and the pain of multiple surgeries. Moreover, the initial fixation of the stent 2 is achieved by using the patient's own cornea, without the need for donor corneas, which can completely avoid the lack of donor corneas and the rejection of allogeneic corneal transplantation. In addition, the stent 2 is located on the anterior surface of the cornea. Compared with the stent provided by the prior art implanted into the corneal stroma, the surgical difficulty and risk are greatly reduced, the trauma is small, the healing period is short, and the healing effect is good.

[0085] In practical applications, when the rear disc 11 and the lens column body 10 are integrally formed, they are assembled together in the following manner:

[0086] a. Snap the connecting ring 21 into the central mounting hole of the stent 2 from top to bottom;

[0087] b. The front end of the lens column body 10 penetrates through the internal thread 210 of the connecting ring 21 (or the internal threaded hole of the central mounting hole), and the lens column body 20 and the stent 2 are rotated in opposite directions so that the stent 2 moves axially along the lens column body 10 towards the direction close to the rear disc 11;

[0088] c. A cosmetic disc is coaxially mounted at the front end of the lens column body 10.

[0089] When the material of the stent is the same as that of the lens column, the connecting ring is omitted, and the stent with internal threads is directly connected to the lens column body.

[0090] In a second aspect, the embodiments of the present invention further provide a method for using a one-time implant artificial cornea. Before applying the artificial cornea provided by the embodiments of the present invention, it is first necessary to determine that the implantation position is in the center of the cornea, drill a hole in the center of the cornea with a trephine, and make a radial side incision on the cornea. The method of use includes the following steps:

[0091] S10. Implant the rear end of the artificial cornea lens column together with the rear disc into the anterior chamber;

[0092] S11. Slide the rear disc of the stent to the posterior surface of the center of the cornea;

[0093] S12. Suture the radial side incision of the cornea until it is watertight;

[0094] S13. Rotate the stent until the stent fits the anterior surface of the cornea;

[0095] S14. Suture and fix the stent on the anterior surface of the eyeball. At this time, the rear disc and the stent clamp the cornea front and back;

[0096] S15. Reinforce the stent with biological tissue or artificial materials.

[0097] As an example, S15 specifically includes:

[0098] S150. Take the auricular cartilage of the patient and drill holes in the auricular cartilage corresponding to the lens column body. Wrap the auricular cartilage around the lens column body through the holes and cover the stent, and suture the auricular cartilage and the cornea at the same time.

[0099] S151. Smoothly pull the Tenon's capsule to cover the surface of the auricular cartilage and suture it to the auricular cartilage.

[0100] Although the present invention has been described in connection with various embodiments, however, in the process of implementing the claimed invention, those skilled in the art can understand and achieve other variations of the disclosed embodiments by viewing the drawings, the disclosure content, and the like. In the specification, the word "comprising" does not exclude other components or steps, and "a" or "one" does not exclude a plurality. A single processor or other unit can implement several functions listed in the specification. Certain measures are recited in different embodiments, but this does not mean that these measures cannot be combined to produce good results.

[0101] Although the present invention has been described in connection with specific features and their embodiments, it is obvious that various modifications and combinations can be made without departing from the spirit and scope of the present invention. Accordingly, this specification and the drawings are only exemplary descriptions of the present invention and are considered to have covered any and all modifications, variations, combinations, or equivalents within the scope of the present invention. Obviously, those skilled in the art can make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if these modifications and variations of the present invention fall within the scope of the present invention and its equivalent technologies, the present invention is also intended to include these changes and modifications.

Claims

1. A one-time implantable artificial cornea that mimics the human eye, characterized in that: The invention comprises a lens column, a bracket and a cosmetic tray; wherein the lens column comprises a lens column body and a rear tray coaxially arranged at a position near the rear end face of the lens column body; the cosmetic tray is coaxially arranged at the front end of the lens column body; the bracket is coaxially and movably arranged on the lens column body between the rear tray and the cosmetic tray; in a state of use, the bracket and the rear tray clamp the cornea in front and in the back; the cosmetic tray has a hole in the center and has an iris texture area and a sclera texture area; the iris texture area is formed with an iris texture layer, and the sclera texture area is formed with a bulbar conjunctival vascular texture layer; The outer periphery of the posterior disc is provided with an annular outer edge forwardly, sealing the posterior disc and the posterior surface of the cornea; The support is a metal support, and the mirror column is at least one of polyhydroxyethyl methacrylate, polymethyl methacrylate, bioceramics or optical glass; The human-eye-imitating one-time implantable artificial cornea further comprises a hollow stepped shaft-shaped connecting ring; the inner wall of the connecting ring is provided with an internal thread, and the front section of the lens column is provided with an external thread matching the internal thread; an annular groove is provided at the shoulder of the outer wall of the hollow stepped shaft, and the inner wall of the central mounting hole of the bracket is inserted into the annular groove in an interference fit assembly manner; and the connecting ring is inserted into the central mounting hole of the bracket from front to back; The beauty tray is thick in the middle and thin on both sides, made of resin, and has a thickness of 0.05 to 0.5 mm at the thickest position; The bracket is provided with a notch or a needle hole for suturing and fixing.

2. The one-time implantable artificial cornea imitating human eyes according to claim 1, characterized in that: The iris texture layer and the imitation bulbar conjunctiva blood vessel texture layer are formed by applying image processing and 3D printing; or, The iris texture layer and the imitation bulbar conjunctiva blood vessel texture layer are at least one of a corneal contact lens, a contact lens, and an iris cover attached to the cosmetic tray.

3. The one-time implantable artificial cornea imitating human eyes according to claim 1, characterized in that: The beauty tray is oval in shape, with a major axis of 11 mm to 26 mm and a minor axis of 5.5 mm to 11 mm.

4. The one-time implantable artificial cornea imitating human eyes according to claim 1, characterized in that: The curvature radius of the beauty tray is 12 mm ± 3.0 mm.

5. The one-time implantable artificial cornea imitating human eyes according to claim 1, characterized in that: The beauty tray is a resin beauty tray, and a notch is provided on the edge of the resin beauty tray for easy clamping.

6. The one-time implantable artificial cornea imitating human eyes according to claim 1, characterized in that: The beauty tray is a resin beauty tray, and the mirror column body is provided with an external thread at the position where the beauty tray is installed, and the diameter is smaller than the diameter at other positions to form a limiting step; the inner wall of the central hole of the beauty tray is provided with an internal thread.

7. The one-time implantable artificial cornea imitating human eyes according to claim 1, characterized in that: The front end surface of the mirror column body is flush with or protrudes from the central opening of the beauty tray.

8. The one-time implantable artificial cornea imitating a human eye according to any one of claims 1 to 7, characterized in that: The diameter of the mirror column body is 2.0 to 3.5 mm, and the diameter of the rear disc is 4 to 7.5 mm; The total length of the mirror column body is 4.5-8.5 mm, of which the length from the rear disc to the rear end face is 1-2 mm, the length from the rear disc to the end of the threaded section is 0.2-0.5 mm, the length of the rear disc is 0.3-0.5 mm, and the length of the threaded section is 3-5.5 mm; The outer circumference size of the stent is 8.5mm~10mm; the curvature radius of the stent is 7.8mm±2.0mm.

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