Moisturizing and soothing sunscreen oil and preparation method thereof

Abstract

The present application relates to the field of cosmetic technology, and specifically discloses a moisturizing and soothing sunscreen oil and a preparation method thereof. The moisturizing and soothing sunscreen oil includes the following components: sunscreen, antioxidant, functional active ingredient, fragrance, dispersant, and emollient. Emollients include fatty alcohol benzoate, dicaprylyl carbonate, and nut seed oil, sunscreen includes isoamyl p-methoxycinnamate, ethylhexyl triazone, and bis-ethylhexyloxyphenol methoxyphenyl triazine, and functional active ingredients include Dunaliella salina extract and Capparis spinosa fruit extract. The moisturizing and soothing sunscreen oil of the present application can not only protect the skin from ultraviolet rays, but also reduce the loss of skin moisture, and can provide a more comprehensive protective effect on the skin.

Description

Technical Field

[0001] The present application relates to the technical field of cosmetics, and more specifically, to a moisturizing and soothing sunscreen oil and a preparation method thereof. Background Art

[0002] In recent decades, due to the emission of chemicals such as chlorofluorocarbons, the ozone layer is gradually being destroyed, which allows more ultraviolet rays to reach the earth's surface. Ultraviolet rays have a variety of potential negative effects on the skin. Long-term exposure to ultraviolet rays can not only cause skin damage such as sunburn, spots, wrinkles, but also lead to an increased incidence of skin cancer. In this context, the research and development of high-performance sunscreen cosmetics is particularly important.

[0003] Sunscreen products are a niche area in the sunscreen cosmetics market. In recent years, consumers' demand for sunscreen products is no longer limited to basic sunscreen effects, but they have begun to pay attention to product texture, packaging design and other additional functions, such as whitening, moisturizing, and anti-oxidation. The sunscreen cosmetics market is developing in a more segmented direction to meet the needs of consumers with different skin types, different occasions, and different needs.

[0004] With respect to the above-mentioned related technologies, the inventors believe that although the sunscreen cosmetics currently available on the market can provide a certain degree of sunscreen effect, it is still difficult to fully reduce the incidence of sunburn on the skin, and the effects of moisturizing and soothing the skin are limited, and therefore it is difficult to be used in occasions exposed to direct sunlight in midsummer. Summary of the invention

[0005] At present, commercially available sunscreen cosmetics are difficult to fully reduce the occurrence of sunburn on the skin, and have limited effects in moisturizing and soothing the skin, and are therefore difficult to be used in situations where the sun is directly exposed in the summer. In order to improve this defect, the present application provides a moisturizing and soothing sunscreen oil and a preparation method thereof.

[0006] In the first aspect, the present application provides a moisturizing and soothing sunscreen oil, which adopts the following technical solution:

[0007] A moisturizing and soothing sunscreen oil comprises the following components by mass fraction: 5-25% sunscreen, 0.01-1% antioxidant, 0.11-3% functional active ingredient, 0.01-1% fragrance, 2-3% dispersant, and the balance is supplemented to 100% by emollients; the emollients include fatty alcohol benzoate, dicaprylyl carbonate and argan seed oil, the sunscreen includes isopentyl p-methoxycinnamate, ethylhexyl triazone and bis-ethylhexyloxyphenol methoxyphenyl triazine, and the functional active ingredient includes Dunaliella salina extract and Capparis spinosa fruit extract.

[0008] By adopting the above technical scheme, dicaprylyl carbonate has good spreadability on the skin surface, and has good compatibility with fatty alcohol benzoate and nut seed oil, which can make the emollient easier to evenly apply on the skin. Therefore, the emollient of the present application can form a film layer with good protective effect on the skin surface, which helps to fully reduce the loss of skin moisture. While the emollient plays a water-retaining role, the composition of isoamyl methoxycinnamate, ethylhexyl triazone and bis-ethylhexyloxyphenol methoxyphenyl triazine can play the synergistic role of conjugated double bonds, triazine rings, benzene rings and other groups, fully realize the absorption of ultraviolet rays, and reduce the damage caused by ultraviolet rays to the skin. On the one hand, the colorless carotenoids phytoene and phytoene in the Dunaliella salina extract can reduce the formation and accumulation of advanced glycation end products (AGEs) in the skin, inhibiting the occurrence of cumulative skin damage and skin aging. On the other hand, the above-mentioned pigments can also produce a synergistic sunscreen effect with sunscreens, improving the absorption effect of sunscreen oil on ultraviolet rays. The vitamins, natural fatty acids and other nutrients in the caper fruit extract and nut seed oil can nourish the skin, improve the skin's own barrier function, and enhance the skin's resistance to ultraviolet rays. The moisturizing and soothing sunscreen oil of the present application can not only protect the skin from ultraviolet rays, but also reduce the loss of skin moisture, and can provide a more comprehensive protection effect on the skin, thereby overcoming the defects in the relevant technology, making the skin less prone to sunburn, cracking, etc., and can fully meet the skin's sun protection needs.

[0009] Preferably, the nut seed oil is macadamia oil or sunflower seed oil.

[0010] By adopting the above technical solution, macadamia oil is rich in monounsaturated fatty acids, especially oleic acid and palmitoleic acid. In addition, macadamia oil also contains a small amount of various fatty acids with carbon atoms ranging from 14 to 24. Sunflower seed oil is also rich in unsaturated fatty acids, vitamin E and carotene, among which the unsaturated fatty acids are mainly oleic acid and linoleic acid. The unsaturated fatty acids in these two nut seed oils help to fully nourish the skin.

[0011] Preferably, the sunscreen agent further comprises a fatty acid-modified sunscreen powder, and the fatty acid-modified sunscreen powder is prepared according to the following method:

[0012] Dissolve fatty acids in ethanol to obtain a fatty acid solution; mix an inorganic sunscreen agent with the fatty acid solution, heat-treat under ultrasonic treatment conditions, then cool and centrifuge, and dry the obtained precipitate to obtain a fatty acid-modified sunscreen powder; the fatty acid includes at least one of oleic acid, palmitoleic acid, and linoleic acid.

[0013] By adopting the above technical solution, the present application expands the ingredients of sunscreen agents and adds fatty acid modified sunscreen powder. Although inorganic sunscreen agents have a wide ultraviolet shielding band, they have poor dispersion effect in organic media and are easy to agglomerate. The fatty acid modified sunscreen powder of the present application is obtained by surface modification of inorganic sunscreen agents with fatty acids under the action of ultrasonic treatment and heating, which can overcome the defect that inorganic sunscreen agents have poor dispersion effect in sunscreen oil. Therefore, after using it as a sunscreen agent, sunscreen oil with better sunscreen effect can be obtained.

[0014] In addition, the present application also prefers specific types of fatty acids, among which oleic acid is the main unsaturated fatty acid in macadamia nut oil and sunflower seed oil, and palmitoleic acid and linoleic acid are unsaturated fatty acids with a relatively high proportion in macadamia nut oil and sunflower seed oil, respectively, except for oleic acid. When these unsaturated fatty acids are selected, since the unsaturated fatty acid composition on the surface of the fatty acid-modified sunscreen powder is close to the unsaturated fatty acid composition in nut seed oil, the fatty acid-modified sunscreen powder has good compatibility with nut seed oil, which enables the fatty acid-modified sunscreen powder to be distributed more evenly in the sunscreen oil, which helps to fully improve the sunscreen effect of the sunscreen oil.

[0015] Preferably, the inorganic sunscreen is prepared according to the following method:

[0016] A zinc chloride aqueous solution is prepared, and ammonia water is added to the zinc chloride aqueous solution to obtain a mixed solution, the mixed solution is subjected to microwave heating treatment under closed conditions, and then cooled, and the cooled mixed solution is vacuum filtered, and the obtained solid is dried to obtain an inorganic sunscreen agent.

[0017] By adopting the above technical scheme, the present application uses zinc chloride and ammonia water as raw materials, and uses a hydrothermal method under microwave heating conditions to prepare nano zinc oxide, that is, an inorganic sunscreen for preparing fatty acid-modified sunscreen powder. The nano zinc oxide synthesized in this way has a high degree of crystallinity and is not easy to agglomerate. Compared with the nano zinc oxide synthesized under non-microwave heating conditions, it has a better ultraviolet shielding effect, which helps to fully improve the sunscreen performance of sunscreen oil. In addition, due to the surface modification of fatty acids, nano zinc oxide is not easy to directly contact with other components in sunscreen oil, thereby reducing the photocatalytic activity of nano zinc oxide, which helps to reduce the degradation of the active ingredients of sunscreen oil.

[0018] Preferably, the sunscreen agent further comprises a silane-modified sunscreen powder, and the silane-modified sunscreen powder is prepared according to the following method:

[0019] The inorganic sunscreen agent is dispersed in water to obtain a dispersion; the pH of the dispersion is adjusted, and then the dispersion is stirred and shaken, and then a silane coupling agent is added, and after heat preservation reaction, the dispersion is filtered, and then the filter residue is washed and dried to obtain a silane-modified sunscreen powder.

[0020] By adopting the above technical solution, the present application expands the ingredients of the sunscreen agent and adds a silane-modified sunscreen powder. The silane-modified sunscreen powder of the present application is obtained by surface-modifying an inorganic sunscreen agent with a silane coupling agent, and the hydrolysis product of the silane coupling agent is bonded on the surface of the inorganic sunscreen agent powder. The silane segment introduced by the silane coupling agent can overcome the defect that the inorganic sunscreen agent has a poor dispersion effect in sunscreen oil, so after using it as a sunscreen agent, a sunscreen oil with better sunscreen effect can be obtained.

[0021] Preferably, the inorganic sunscreen is prepared according to the following method:

[0022] Nano titanium dioxide is dispersed in ammonia water, and then heated in a water bath after ultrasonic treatment. Then zinc acetate solution is added, and the reaction is continued before suction filtration. The filter residue is washed and dried, and then calcined to obtain an inorganic sunscreen.

[0023] By adopting the above technical scheme, the present application uses nano titanium dioxide as the core material, prepares tetraammine zinc hydroxide on the surface of nano titanium dioxide through the reaction of ammonia water and zinc acetate, and then decomposes tetraammine zinc hydroxide by roasting to obtain nano titanium dioxide with zinc oxide loaded on the surface. The loading of zinc oxide can improve the dispersion effect of nano titanium dioxide, and exert stronger ultraviolet shielding performance through the synergistic effect of zinc oxide and titanium dioxide. Therefore, by using this material as an inorganic sunscreen agent for preparing silane-modified sunscreen powder, a sunscreen oil with better sunscreen effect can be obtained.

[0024] Preferably, in the method for preparing the inorganic sunscreen, ethyl orthosilicate is added simultaneously with the zinc acetate solution, and the molar ratio of ethyl orthosilicate to nano titanium dioxide is 1:(4-6).

[0025] By adopting the above technical scheme, the present application further defines the method for preparing inorganic sunscreens, and adds tetraethyl orthosilicate, which can be hydrolyzed under the action of ammonia water, and the hydrolysis product can be attached to the surface of nano titanium dioxide together with zinc oxide. The hydrolysis product of tetraethyl orthosilicate will be converted into silicon dioxide after roasting, and silicon dioxide can inhibit the photocatalytic activity of zinc oxide and titanium dioxide. At the same time, the surface modification of inorganic sunscreens by silane coupling agents can further inhibit the photocatalytic activity of loaded zinc oxide. It can be seen that while achieving a better ultraviolet shielding effect by loading titanium dioxide with zinc oxide, the present application also successfully combines inorganic loading and organic surface grafting modification, exerts a good synergistic effect, effectively reduces the photocatalytic activity of zinc oxide loaded titanium dioxide, thereby reducing the negative impact caused by the photocatalytic activity, and helps to reduce the degradation of the active ingredients of sunscreen oil.

[0026] In general, the sunscreen of the present application combines isopentyl p-methoxycinnamate, ethylhexyl triazone and bis-ethylhexyloxyphenol methoxyphenyl triazine with fatty acid-modified sunscreen powder and silane-modified sunscreen powder in a reasonable manner and then acts as a sunscreen together. The advantage is that the sunscreen effect is greatly improved through the synergistic effect of chemical sunscreen and physical sunscreen, and the surface modification of fatty acids and silanes respectively improves the dispersibility, stability and adhesion ability of the physical sunscreen.

[0027] Preferably, in the method for preparing the inorganic sunscreen, the nano titanium dioxide used is rutile nano titanium dioxide or anatase nano titanium dioxide.

[0028] By adopting the above technical solution, the present application optimizes the crystal type of nano titanium dioxide. Among the two types of nano titanium dioxide, although anatase nano titanium dioxide has a higher photocatalytic activity, zinc oxide, silicon dioxide and silane coupling agent jointly block the direct contact between titanium dioxide and sunscreen components, and silicon dioxide and silane coupling agent jointly block the direct contact between zinc oxide and surrounding sunscreen components, so the photocatalytic activity of zinc oxide and titanium dioxide can be fully suppressed. In this case, the strong ultraviolet shielding effect of anatase nano titanium dioxide can be fully exerted, and the negative impact brought by the photocatalytic activity is small, which helps to fully improve the sunscreen performance of sunscreen.

[0029] Preferably, the dispersant is polyvinyl pyrrolidone, sodium hexametaphosphate and polyethylene glycol.

[0030] By adopting the above technical solution, polyvinyl pyrrolidone has good biocompatibility and physiological inertness, and has certain film-forming properties and colloid protection capabilities; sodium hexametaphosphate absorbs moisture in the air and becomes viscous; polyethylene glycol is non-irritating to the skin and can play its high molecular steric hindrance role in sunscreen. Under the joint action of polyvinyl pyrrolidone, sodium hexametaphosphate and polyethylene glycol, the various components in the sunscreen can maintain good compatibility, and it is not easy to stratify, so it can maintain uniformity and stability for a long time.

[0031] In a second aspect, the present application provides a method for preparing a moisturizing and soothing sunscreen oil, using the following technical solution.

[0032] A method for preparing a moisturizing and soothing sunscreen oil comprises the following steps:

[0033] (1) Mixing the fragrance, the functional active ingredient, the antioxidant and half the weight of the emollient, stirring to obtain a premix for later use;

[0034] (2) The premix, sunscreen and remaining emollient are mixed and stirred to obtain a moisturizing and soothing sunscreen oil.

[0035] By adopting the above technical scheme, the present application first mixes the fragrance, functional active ingredients, antioxidants and other components with smaller amounts with half of the emollient, and then mixes the obtained mixture with the remaining half of the emollient and the sunscreen, so that each component can achieve a more uniform dispersion effect, which helps to improve the sunscreen effect of the sunscreen oil.

[0036] In summary, this application has the following beneficial effects:

[0037] 1. The moisturizing and soothing sunscreen oil of the present application can not only protect the skin from ultraviolet rays, but also reduce the loss of moisture from the skin, thus providing a more comprehensive protective effect on the skin, thereby overcoming the defects in the relevant technologies and making the skin less prone to sunburn, cracking, etc.

[0038] 2. The fatty acid-modified sunscreen powder and silane-modified sunscreen powder of the present application can overcome the defect that inorganic sunscreen agents have poor dispersion effect in sunscreen oils. When these two components are used as sunscreen agents, sunscreen oils with better sunscreen effects can be obtained.

[0039] 3. The silane-modified sunscreen powder of the present application blocks direct contact between titanium dioxide and sunscreen components through zinc oxide, silicon dioxide and silane coupling agent, and blocks direct contact between zinc oxide and surrounding sunscreen components through silicon dioxide and silane coupling agent, so that the photocatalytic activity of zinc oxide and titanium dioxide can be fully suppressed, overcoming the negative impact of photocatalytic activity, and making full use of the strong ultraviolet shielding effect of anatase nano-titanium dioxide, which helps to improve the sunscreen performance of sunscreen. DETAILED DESCRIPTION

[0040] The present application is further described in detail below in conjunction with embodiments, preparation examples and comparative examples. The raw materials involved in the present application can all be obtained commercially.

[0041] Preparation example of fatty acid modified sunscreen powder

[0042] The following is an explanation using Preparation Example 1.

[0043] Preparation Example 1

[0044] In this preparation example, the fatty acid selected is caprylic acid.

[0045] In this preparation example, the inorganic sunscreen agent is prepared according to the following method:

[0046] 0.3 g of zinc chloride was added to 40 mL of deionized water to obtain a zinc chloride aqueous solution, 2 mL of 8 mol / L ammonia water was added to the zinc chloride aqueous solution to obtain a mixed solution, the mixed solution was heated at 150° C. for 2 h under closed conditions, and then the mixed solution was cooled to 25° C., the cooled mixed solution was vacuum filtered, and the obtained solid was dried in an oven at 60° C. to obtain an inorganic sunscreen.

[0047] In this preparation example, the fatty acid-modified sunscreen powder is prepared according to the following method:

[0048] 1.8 g of fatty acid was dissolved in 100 mL of anhydrous ethanol to obtain a fatty acid solution; 0.5 g of powdered inorganic sunscreen was mixed with the fatty acid solution, heated at 60° C. for 30 min under 500 W ultrasonic treatment conditions, then cooled to 25° C. and centrifuged at 8000 rpm for 10 min, and the obtained precipitate was dried in an oven at 60° C. for 1 h to obtain a fatty acid-modified sunscreen powder.

[0049] Preparation Example 2

[0050] The difference between this preparation example and preparation example 1 is that the fatty acid is a mixture of oleic acid and palmitoleic acid in a weight ratio of 5:1.

[0051] Preparation Example 3

[0052] The difference between this preparation example and preparation example 1 is that the fatty acid is a mixture of oleic acid and linoleic acid in a weight ratio of 5:1.

[0053] Preparation Example 4

[0054] The difference between this preparation example and preparation example 3 is that the heating treatment conditions are adjusted from heating the mixed solution at a temperature of 150°C for 2 hours under closed conditions to microwave heating treatment at a temperature of 90°C and a microwave power of 250 W for 10 minutes under closed conditions.

[0055] Preparation example of silane-modified sunscreen powder

[0056] The following is an explanation using Preparation Example 5.

[0057] Preparation Example 5

[0058] In this preparation example, the inorganic sunscreen used is rutile nano-titanium dioxide.

[0059] In this preparation example, the silane-modified sunscreen powder was prepared according to the following method:

[0060] 10 g of powdered inorganic sunscreen was dispersed in 190 mL of water to obtain a dispersion; the pH of the dispersion was adjusted to 4 using sodium hydroxide solution and hydrochloric acid, followed by 30 min of magnetic stirring and 30 min of ultrasonic oscillation, and then 2 g of silane coupling agent KH550 was added. After the reaction was kept at 80° C. for 4 h, the reaction system was cooled to 25° C. and filtered, and the filter residue was washed with water and ethanol, and then dried in a vacuum drying oven at 80° C. for 12 h to obtain a silane-modified sunscreen powder.

[0061] Preparation Example 6

[0062] The difference between this preparation example and preparation example 5 is that the inorganic sunscreen agent is prepared according to the following method:

[0063] 1.2 g of rutile nano-titanium dioxide was dispersed in 30 mL of 8 mol / L ammonia water, and ultrasonically treated at 500 W for 15 min. The mixture was heated in a water bath at 90° C., and then 50 mL of 0.5 mol / L zinc acetate solution was added. The reaction was continued for 30 min, and then the mixture was filtered and washed with ammonia water. The residue was dried at 80° C. for 12 h, and then calcined at 600° C. for 6 h to obtain an inorganic sunscreen.

[0064] Preparation Example 7

[0065] The difference between this preparation example and preparation example 6 is that in the method for preparing the inorganic sunscreen, ethyl orthosilicate is added at the same time as the zinc acetate solution, and the molar ratio of ethyl orthosilicate to nano titanium dioxide is 1:10.

[0066] Preparation Example 8

[0067] The difference between this preparation example and preparation example 7 is that in the method for preparing the inorganic sunscreen, the molar ratio of ethyl orthosilicate to nano titanium dioxide is 1:5.

[0068] Preparation Example 9

[0069] The difference between this preparation example and preparation example 7 is that in the method for preparing the inorganic sunscreen, the molar ratio of ethyl orthosilicate to nano titanium dioxide is 1:4.

[0070] Preparation Example 10

[0071] The difference between this preparation example and preparation example 7 is that in the method for preparing the inorganic sunscreen, the molar ratio of ethyl orthosilicate to nano titanium dioxide is 1:3.

[0072] Preparation Example 11

[0073] The difference between this preparation example and preparation example 10 is that in the method for preparing the inorganic sunscreen agent, the nano titanium dioxide used is anatase nano titanium dioxide.

[0074] Examples 1-5

[0075] The following description is given by taking Example 1 as an example.

[0076] Example 1

[0077] This embodiment provides a moisturizing and soothing sunscreen oil, which is composed of emollients, sunscreens, antioxidants, functional active ingredients, and fragrances. The mass fractions of the components in the emollient and in the sunscreen oil are: fatty alcohol benzoate (CAS No.: 68411-27-8) 20%, dicaprylyl carbonate 70.87%, nut seed oil 2%, totaling 92.87%, and the nut seed oil is macadamia oil (CAS: 128497-20-1). The mass fractions of the components in the sunscreen and in the sunscreen oil are: isopentyl p-methoxycinnamate 2%, ethylhexyl triazone 1%, bis-ethylhexyloxyphenol methoxyphenyl triazine 2%, totaling 5%. The mass fraction of the antioxidant in the sunscreen oil is 0.01%, and tocopherol is selected. The components of the active ingredients and their mass fractions in the sunscreen are: Dunaliella salina extract (EINECS No.: 921-534-9) 0.1%, Capparis spinosa fruit extract (CAS No.: 89958-23-6) 0.01%, and the total is 0.11%. The mass fraction of fragrance in the sunscreen is 0.01%.

[0078] This embodiment provides a method for preparing a moisturizing and soothing sunscreen oil, comprising the following steps:

[0079] (1) Mixing the fragrance, the functional active ingredient, the antioxidant and half the weight of the emollient, stirring to obtain a premix for later use;

[0080] (2) The premix, sunscreen and remaining emollient are mixed and stirred to obtain a moisturizing and soothing sunscreen oil.

[0081] As shown in Table 1, the differences between Examples 1-5 are mainly in the different raw material ratios of the sunscreen oils.

[0082] Table 1 Raw material ratio of sunscreen oil

[0083]

[0084] Example 6

[0085] The difference between this embodiment and embodiment 5 is that the sunscreen agent includes modified sunscreen powder in addition to isopentyl p-methoxycinnamate, ethylhexyl triazone and bis-ethylhexyloxyphenol methoxyphenyl triazine, and the modified sunscreen powder is fatty acid modified sunscreen powder, and the fatty acid modified sunscreen powder is prepared according to the method of preparation example 1. The ratio of isopentyl p-methoxycinnamate, ethylhexyl triazone, bis-ethylhexyloxyphenol methoxyphenyl triazine and modified sunscreen powder is 2:1:2:1.25.

[0086] Example 7

[0087] The difference between this embodiment and embodiment 6 is that the fatty acid-modified sunscreen powder is prepared according to the method of preparation example 2.

[0088] Example 8

[0089] The difference between this embodiment and embodiment 6 is that the nut seed oil is sunflower seed oil (CAS No.: 8001-21-6).

[0090] Example 9

[0091] The difference between this embodiment and embodiment 8 is that the fatty acid-modified sunscreen powder is prepared according to the method of preparation example 3.

[0092] Example 10

[0093] The difference between this embodiment and embodiment 9 is that the fatty acid-modified sunscreen powder is prepared according to the method of preparation example 4.

[0094] Embodiment 11

[0095] The difference between this embodiment and embodiment 10 is that the modified sunscreen powder further comprises a silane-modified sunscreen powder prepared by the method of preparation example 5, and the weight ratio of the silane-modified sunscreen powder to the fatty acid-modified sunscreen powder is 1:1.

[0096] As shown in Table 2, the difference between Examples 11-17 is that different preparation examples were used as reference when preparing the silane-modified sunscreen powder.

[0097] Table 2 Preparation example of silane-modified sunscreen powder

[0098]

[0099] Embodiment 18

[0100] The difference between this embodiment and embodiment 11 is that all modified sunscreen powders are silane-modified sunscreen powders, and the silane-modified sunscreen powders are prepared by referring to the method of preparation example 5.

[0101] Comparative Example

[0102] Comparative Example 1

[0103] The difference between this comparative example and Example 3 is that dicaprylyl carbonate is replaced by the same weight of fatty alcohol benzoate.

[0104] Comparative Example 2

[0105] The difference between this comparative example and Example 3 is that the nut seed oil is replaced with the same weight of fatty alcohol benzoate.

[0106] Comparative Example 3

[0107] The difference between this comparative example and Example 3 is that the fatty alcohol benzoate is replaced by the same weight of dicaprylyl carbonate.

[0108] Comparative Example 4

[0109] The difference between this comparative example and Example 3 is that isoamyl p-methoxycinnamate is replaced by ethylhexyl triazone of the same weight.

[0110] Comparative Example 5

[0111] The difference between this comparative example and Example 3 is that ethylhexyl triazone is replaced by the same weight of bis-ethylhexyloxyphenol methoxyphenyl triazine.

[0112] Comparative Example 6

[0113] The difference between this comparative example and Example 3 is that bis-ethylhexyloxyphenol methoxyphenyl triazine is replaced by the same weight of isoamyl p-methoxycinnamate.

[0114] Comparative Example 7

[0115] The difference between this comparative example and Example 3 is that, on the basis of Example 3, the Dunaliella salina extract in the formula is completely replaced by Capparis spinosa fruit extract.

[0116] Comparative Example 8

[0117] The difference between this comparative example and Example 3 is that, on the basis of Example 3, the Capparis spinosa fruit extract in the formula is completely replaced by the Dunaliella salina extract.

[0118] Performance testing methods

[0119] 1. Cosmetic performance testing

[0120] The sunscreen oils in the embodiments and comparative examples were tested with reference to the Technical Specifications for Safety of Cosmetics (2015 edition), and the testing items included microbial testing, sunscreen content testing, toxicology testing, SPF value testing, and PFA value testing.

[0121] Among them, the test results of microbial detection are shown in Table 3; the test results of sunscreen content detection are shown in Table 4. The components targeted by sunscreen content detection are the 15 components included in 5.1 of "Technical Specifications for Safety of Cosmetics" (2015 edition), such as phenylbenzimidazole sulfonic acid; toxicology tests include skin irritation test, skin allergy test, skin phototoxicity test and human skin patch test, and the test results are shown in Table 5; the results of SPF value detection and PFA value detection are shown in Table 6.

[0122] 2. Moisturizing effect

[0123] Test instrument: TewameterTM300 moisture loss tester, produced by German CK company.

[0124] Subjects: A total of 25 healthy volunteers were selected.

[0125] Inclusion criteria: (1) Aged 21-59 years, both men and women, with no history of allergic reactions to cosmetics; (2) The subject's forearm skin is intact, without any scars, injuries, or other factors that may affect the assessment; (3) The baseline value of the forearm test area measured by a skin moisture tester should be between 15 and 45.

[0126] Exclusion criteria: (1) Participants who are currently or have participated in other clinical trials before the start of this study; (2) Those who are in the period of preparing for pregnancy, pregnant, breastfeeding, or within six months after giving birth; (3) Those who have taken corticosteroids, antibiotics, retinoic acid drugs, or other anti-acne drugs in the past two weeks; (4) Subjects with active skin diseases that have not been cured clinically; (5) The test area has undergone laser beauty or chemical peels.

[0127] Test method: The test part cannot use any products 2-3 days before the test, and cannot come into contact with water 1-3 hours before the test. Before the test, the subjects need to clean the flexor side of both forearms, wipe them gently with a dry paper towel, and sit quietly in the human efficacy evaluation room (temperature 20-22℃, humidity 40%-60%) for 30 minutes. No water or beverages are allowed during the test.

[0128] During the test, the sample is applied according to the method described in "QB / T4256-2011 Guidelines for Evaluation of Cosmetic Moisturizing Efficacy", and the transepidermal water loss value is tested before and 8 hours after the product is used. Each area is measured in parallel 3 times for each measurement, and the average value is taken. The test of the same subject is completed by the same measurement personnel. The measuring probe should be cleaned between two measurements. The test site should be kept consistent between the two test time points.

[0129] The calculation method of the water loss value change rate is as follows:

[0130] Change rate of water loss value = transepidermal water loss value after use / transepidermal water loss value before use × 100%.

[0131] The sunscreen oils of various embodiments and comparative examples (including the sunscreen cosmetics of comparative example 1) were tested, and the water loss value change rate of comparative example 1 was used as a benchmark to calculate the ratio between the water loss value change rate of each embodiment and comparative example and the water loss value change rate of comparative example 1. The ratio was recorded as the relative water loss rate. The results are shown in Table 7.

[0132] 3. Fatty acid modified sunscreen powder performance test

[0133] Test method: Take the photodegradation of methylene blue as the probe reaction to test the photocatalytic activity of the sample. Weigh 0.04g fatty acid modified sunscreen powder sample and suspend it in 50mL methylene blue aqueous solution with a mass concentration of 4mg / L. React in a dark room for 1h to achieve adsorption-desorption equilibrium. Turn on the light source (500W xenon lamp) and carry out the photodegradation reaction at room temperature. Take 1mL of the reaction solution every 30min, filter out the powder and measure the absorbance of the methylene blue solution at 665nm. The degradation rate of methylene blue is calculated based on the absorbance measured after 6h and the initial absorbance.

[0134] Test group: fatty acid-modified sunscreen powder of Preparation Examples 1-4.

[0135] Control group: the inorganic sunscreen agent before being modified with fatty acid in Preparation Example 1.

[0136] Based on the test results of the control group samples, the ratio of the degradation rate measured in the test group to the degradation rate measured in the control group was calculated, and the ratio was recorded as the photocatalytic activity residual rate. The results are shown in Table 8.

[0137] 4. Silane modified sunscreen powder performance test

[0138] Test method: Same as the performance test of fatty acid modified sunscreen powder.

[0139] Test group: silane-modified sunscreen powder of Preparation Examples 5-11.

[0140] Control group: rutile nano-titanium dioxide used in Preparation Example 5.

[0141] Based on the test results of the control group samples, the ratio of the degradation rate measured in the test group to the degradation rate measured in the control group was calculated, and the ratio was recorded as the photocatalytic activity residual rate. The results are shown in Table 9.

[0142] Table 3 Microbiological detection

[0143]

[0144] Table 4 Sunscreen content detection

[0145]

[0146] Table 5 Toxicology test results

[0147]

[0148] Table 6 SPF value and PFA value test results

[0149]

[0150] Table 7 Relative water loss rate test results

[0151]

[0152] Table 8 Fatty acid modified sunscreen powder performance test results

[0153]

[0154] Table 9 Silane modified sunscreen powder performance test results

[0155]

[0156] It can be seen from Examples 1-18 and Tables 3-5 that the sunscreen oil of the present application not only meets the requirements of microbial testing and sunscreen content testing, but also shows no adverse effects on the skin in toxicology tests.

[0157] Combining Example 3 and Comparative Examples 1-3 with Table 7, it can be seen that when fatty alcohol benzoate, dicaprylyl carbonate and argan seed oil are not used in combination, the moisturizing performance of the sunscreen oil is poor.

[0158] Combining Example 3 and Comparative Examples 4-6 with Table 6, it can be seen that when fatty alcohol benzoate is not used in combination with isoamyl p-methoxycinnamate, ethylhexyl triazone and bis-ethylhexyloxyphenol methoxyphenyl triazine, these three sunscreens are difficult to fully exert their synergistic sunscreen effect, resulting in poor sunscreen performance of the sunscreen oil.

[0159] Combining Example 3 and Comparative Examples 7-8 with Tables 6-7, it can be seen that when the components of the sunscreen lack either the Dunaliella salina extract or the Capparis spinosa fruit extract, the sunscreen performance and moisturizing performance of the sunscreen are poor.

[0160] It can be seen from Example 5 and Example 6 and Table 6 that since the inorganic sunscreen has a wider ultraviolet shielding band, and the inorganic sunscreen is processed by fatty acid to prepare a fatty acid-modified powder with good dispersion effect, the sunscreen effect of the sunscreen oil is improved to a certain extent under the joint action of the various components of the sunscreen.

[0161] It can be seen from Example 6 and Example 7 and Table 6 that when the nut seed oil is macadamia nut oil, since the method of Preparation Example 2 uses a fatty acid that is closer to the components of macadamia nut oil to modify the inorganic sunscreen agent, the fatty acid-modified powder has a better dispersion effect, making the fatty acid-modified sunscreen powder of Preparation Example 2 more helpful in improving the sunscreen effect of sunscreen oil.

[0162] Combining Example 6 with Example 8 and Example 9 and Table 6, it can be seen that when sunflower seed oil is used as the nut seed oil, the method of Preparation Example 3 uses a fatty acid that is closer to the composition of sunflower seed oil to modify the inorganic sunscreen agent, so the obtained fatty acid-modified sunscreen powder has a better dispersion effect and is more helpful to improve the sunscreen effect of the sunscreen oil.

[0163] It can be seen from Example 9, Example 10 and Table 6 that when the inorganic sunscreen agent used to prepare the fatty acid-modified sunscreen powder is nano zinc oxide obtained by microwave heating, the sunscreen oil can obtain a better sunscreen effect.

[0164] It can be seen from the combination of Preparation Examples 1-4 and Table 8 that the modification treatment of fatty acid can inhibit the photocatalytic activity of zinc oxide and help reduce the negative impact of the photocatalytic activity of zinc oxide.

[0165] It can be seen from Example 10, Example 11, Example 18 and Table 6 that the silane-modified sunscreen powder and the fatty acid-modified sunscreen powder can help improve the sunscreen effect of the sunscreen oil when used together.

[0166] It can be seen from Example 11, Example 12 and Table 6 that, compared with nano-titanium dioxide, nano-titanium dioxide with zinc oxide loaded on the surface helps to improve the sunscreen effect of sunscreen oil.

[0167] It can be seen from Preparation Examples 7-10 and Table 9 that in the method for preparing silane-modified sunscreen powder, the addition of tetraethyl orthosilicate can reduce the photocatalytic activity of the silane-modified sunscreen powder, so that the components in the sunscreen oil are not easily degraded by the photocatalytic reaction. When the molar ratio of tetraethyl orthosilicate to nano-titanium dioxide is 1:(4-6), the photocatalytic activity of the silane-modified sunscreen powder can be better suppressed.

[0168] From Example 16 and Example 17 and Table 6 and Table 9, it can be seen that when anatase nano-titanium dioxide is used to prepare the silane-modified sunscreen powder, the sunscreen performance of the sunscreen oil is greatly improved, while the photocatalytic activity of the silane-modified sunscreen powder does not show a significant increase, indicating that the method of the present application can fully exert the ultraviolet shielding effect of nano-titanium dioxide while fully reducing the negative impact of the photocatalytic activity of nano-titanium dioxide.

[0169] The above embodiments are merely explanations of the present application and are not limitations of the present application. After reading this specification, those skilled in the art may make modifications to the embodiments of the present application without any creative contribution as needed. However, as long as they are within the scope of the claims of the present application, they are protected by the patent law.

Claims

1. A moisturizing and soothing sunscreen oil, characterized in that: The composition comprises the following components by mass fraction: 5-25% sunscreen, 0.01-1% antioxidant, 0.11-3% active ingredient, 0.01-1% fragrance, 2-3% dispersant, and the balance is made up to 100% by emollient; the emollient is fatty alcohol benzoate, dicaprylyl carbonate and nut seed oil, and the nut seed oil is macadamia oil or sunflower seed oil; the sunscreen is isoamyl p-methoxycinnamate, ethylhexyl triazone, bis-ethylhexyloxyphenol methoxyphenyl triazine, fatty acid-modified sunscreen powder and silane-modified sunscreen powder, and the active ingredient is Dunaliella salina extract and Capparis spinosa fruit extract; The fatty acid modified sunscreen powder is prepared according to the following method: Dissolving fatty acids in ethanol to obtain a fatty acid solution; mixing an inorganic sunscreen agent with the fatty acid solution, heating the mixture under ultrasonic treatment, cooling the mixture and centrifuging the mixture; and drying the obtained precipitate to obtain a fatty acid-modified sunscreen powder; the fatty acid comprises at least one of oleic acid, palmitoleic acid and linoleic acid; The silane-modified sunscreen powder is prepared according to the following method: The inorganic sunscreen agent is dispersed in water to obtain a dispersion; the pH of the dispersion is adjusted, and then the dispersion is stirred and shaken, and then a silane coupling agent is added, and after heat preservation reaction, the dispersion is filtered, and then the filter residue is washed and dried to obtain a silane-modified sunscreen powder.

2. The moisturizing and soothing sunscreen oil according to claim 1, characterized in that: The inorganic sunscreen agent used to prepare the fatty acid-modified sunscreen powder is prepared according to the following method: A zinc chloride aqueous solution is prepared, and ammonia water is added to the zinc chloride aqueous solution to obtain a mixed solution, the mixed solution is subjected to microwave heating treatment under closed conditions, and then cooled, and the cooled mixed solution is vacuum filtered, and the obtained solid is dried to obtain an inorganic sunscreen agent.

3. The moisturizing and soothing sunscreen oil according to claim 1, characterized in that: The inorganic sunscreen agent used to prepare the silane-modified sunscreen powder is prepared according to the following method: Nano titanium dioxide is dispersed in ammonia water, and then heated in a water bath after ultrasonic treatment. Then zinc acetate solution is added, and the reaction is continued before suction filtration. The filter residue is washed and dried, and then calcined to obtain an inorganic sunscreen.

4. The moisturizing and soothing sunscreen oil according to claim 3, characterized in that: In the preparation method of the inorganic sunscreen agent for preparing the silane-modified sunscreen powder, ethyl orthosilicate is added at the same time as the zinc acetate solution, and the molar ratio of ethyl orthosilicate to nano titanium dioxide is 1:(4-6).

5. The moisturizing and soothing sunscreen oil according to claim 4, characterized in that: In the preparation method of the inorganic sunscreen agent used to prepare the silane-modified sunscreen powder, the nano titanium dioxide used is rutile nano titanium dioxide or anatase nano titanium dioxide.

6. The moisturizing and soothing sunscreen oil according to claim 1, characterized in that: The dispersant is polyvinyl pyrrolidone, sodium hexametaphosphate and polyethylene glycol.

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