A filtering and extracting device for biomedical production

By designing a filtration and extraction device for biopharmaceutical production with a rotating extraction cylinder and active filtration function, the problem in the existing technology that the filtration and extraction process cannot be actively adjusted is solved, and efficient and precise extraction results are achieved.

CN118874038BActive Publication Date: 2025-01-21NINGBO HEXIN PHARMA EQUIPS
View PDF 2 Cites 0 Cited by

Patent Information

Application Number
CN202411379953.3
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-09-30
Publication Date
2025-01-21
Estimated Expiration
2044-09-30

AI Technical Summary

Technical Problem

In the existing biomedical production, the filtration and extraction process cannot be actively adjusted, which affects efficiency and accuracy, and the combination control of the extraction device is difficult, which reduces the performance of the device.

Method used

Design a filtration and extraction device that includes a box, an extraction cylinder, an extraction box, a filter plate and a collection port. The extraction box and filter plate are driven by the rotation of the extraction cylinder inside the box for active filtration, and the rack rod is used for active filtering. and isolation cylinder to achieve unified collection of discharged materials and avoid interference.

Benefits of technology

It achieves high efficiency and precision of filtration and extraction in biopharmaceutical production. Through the design of active filtration and unified discharge, the performance and adaptability of the extraction device are improved.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN118874038B_ABST
    Figure CN118874038B_ABST
Patent Text Reader

Abstract

The invention discloses a filtering and extracting device for biomedical production, comprising a box body, a sealing hole is provided at the bottom of the box body, an extraction cylinder is rotatably installed inside the sealing hole, the outer surface of the extraction cylinder is fixedly connected to the extraction box body, a filter plate is fixedly connected to the opening position of the extraction box body, a collecting port is provided on the outer surface of the extraction cylinder, the collecting port is located on one side of the interior of the extraction box body, a conical guide plate is fixedly connected to the one end surface of the extraction cylinder, a mounting frame is fixedly connected to the upper end surface of the box body, a rack pull rod is slidably installed at the middle position of the interior of the mounting frame, the rack pull rod is slidably connected to the interior of the extraction cylinder, can be rotatably adjusted to perform active filtering, thereby ensuring efficiency and accuracy, and an isolation cylinder is installed through the internal rack pull rod, so that materials can be discharged after unified collection to avoid interference, and the device is efficient, stable and highly adaptable.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The invention relates to the field of medicine production, and more specifically to a filtering and extracting device for biomedicine production. Background Art

[0002] At present, with the rapid development of my country, the biomedical industry has absorbed the world's top technology and made great progress. In the pharmaceutical process, filtering and purifying drugs is an important part. At the same time, biomedicine is to understand the structure, function and other life phenomena of the human body from the multi-level of molecules, cells, tissues, organs and even the entire human system, so as to study artificial materials, products, devices and system technologies for disease prevention, treatment, human function assistance and health care. The pharmaceutical industry and the biomedical engineering industry are the two pillars of the modern pharmaceutical industry. Due to the different composition of the pharmaceutical industry, the definition and scope of the biotechnology industry by various countries and organizations are not unified, and even the views of different people are often very different. In the production process of the biomedical industry, it is often necessary to use filtering and extraction devices to soak and extract the components in the raw materials.

[0003] Most biological drugs exist in biological tissues or cells. To improve the extraction rate, the crushing process of biological tissues and cells is very important, and there are five commonly used crushing methods: A. Grinding method, which belongs to the mechanical crushing method, and the equipment used includes tissue crusher, colloid mill, homogenizer, homogenizer, ball mill, mortar, etc.; B. Pressure method, this method has two types of pressure and pressure reduction, and the commonly used French autoclave has good effect; C. Repeated freeze-thaw method, this method has simple equipment and good activity retention, but it takes a long time; D. Ultrasonic oscillation crushing method, this method has a better crushing effect, but due to local heating, there is a loss of activity; E. Autolysis or enzymatic hydrolysis method, which is less used, and the extraction of active substances in biological tissues must be carried out immediately after cell crushing. In the extraction process (1) the extraction reagent should be selected according to the properties of the active substance. The main extraction reagents are: water, buffer solution, salt solution, ethanol, and other organic solvents (such as chloroform, acetone, etc.). (2) Consider the amount of extraction solvent (solid-liquid ratio) and the number of extractions and extraction time. (3) Pay attention to factors such as extraction temperature, pH, denaturant, etc. This will ensure that the active substances are fully extracted and not denatured.

[0004] However, in the production and extraction process of biopharmaceuticals, the effective ingredients are obtained directly through extraction with extracting liquids, which can only be extracted passively by filtering and cannot be actively adjusted, which affects the efficiency and accuracy, is not conducive to the combined control of the extraction device, and reduces the performance of the extraction device. A new filtering extraction device needs to be proposed. Summary of the invention

[0005] In view of the problems existing in the prior art, the purpose of the present invention is to provide a filtering and extraction device for biomedical production. By installing an extraction cylinder inside the box, combined with the extraction box and the collection port on the surface, it can be rotated and adjusted to perform active filtration to ensure efficiency and accuracy, and the isolation cylinder is installed through the internal rack pull rod, so that the materials can be discharged after unified collection to avoid interference. The device is efficient, stable and highly adaptable.

[0006] To solve the above problems, the present invention adopts the following technical solutions.

[0007] A filtering and extracting device for biomedical production, comprising a box body, a sealing hole is provided at the bottom of the box body, an extraction cylinder is rotatably installed inside the sealing hole, the outer surface of the extraction cylinder is fixedly connected to the extraction box body, a filter plate is fixedly connected to the opening position of the extraction box body, a collection port is provided on the outer surface of the extraction cylinder, the collection port is located on one side of the interior of the extraction box body, a conical guide plate is fixedly connected to one end surface of the extraction cylinder, a mounting frame is fixedly connected to the upper end surface of the box body, a rack pull rod is slidably installed at the middle position inside the mounting frame, and the rack pull rod is slidably connected to the interior of the extraction cylinder;

[0008] One end of the rack pull rod is fixedly connected to an isolation cylinder, one end of the isolation cylinder is fixedly connected to a conical head, the conical head is fixedly connected to one end of the rack pull rod, the outer surface of the isolation cylinder is fixedly connected to a sealing cylinder, the sealing cylinder is slidably connected to the inner wall surface of the extraction cylinder, the inner side of the mounting frame is fixedly connected to a collecting bucket, the bottom of the collecting bucket is provided with a circular avoidance hole, the circular avoidance hole is sleeved on one end surface of the extraction cylinder, one side of the collecting bucket is fixedly connected to a discharge plate, the discharge plate is fixedly connected to one side position of the mounting frame;

[0009] The upper surface of the mounting frame is fixedly connected to a driving motor, one end of the driving motor is installed with a gear, the gear is meshed with one side of the rack pull rod, the bottom two ends of the box body are fixedly connected to a fixed cylinder, a sliding rod is slidably installed inside the fixed cylinder, a movable bracket is fixedly installed on one end of the sliding rod, a buffer spring is slidably installed on the other end of the sliding rod, and the buffer spring is slidably installed inside the fixed cylinder;

[0010] The method for using the extraction device comprises the following steps:

[0011] S1. Add the treated extract into the box, control the liquid level to cover the extraction box, and part of the extract will pass through the filter plate into the extraction box, and then flow into the extraction cylinder from the collection port;

[0012] S2, control the extraction cylinder to rotate inside the box, and rotate with the extraction box and the filter plate, the filter plate actively impacts the extraction liquid, filters and extracts the effective components inside, and the filtered effective components enter the extraction box and continue to accumulate;

[0013] S3, the accumulated effective ingredients enter the extraction cylinder through the collection port, gradually accumulate inside the extraction cylinder, and are stored at the upper end of the isolation cylinder, and continue to rotate for filtering and extraction;

[0014] S4, the sliding rod can be slidably adjusted by supporting the fixed cylinder, and the internal buffer spring can be used for buffering support, buffering adjustment of the movable bracket, support adjustment of the connected extraction cylinder, and up and down oscillation adjustment;

[0015] S5, the extraction cylinder oscillates up and down inside the box, and the extraction box and the filter plate oscillate up and down in the extraction liquid to assist in cleaning the surface;

[0016] S6. After the filtration and extraction is completed, the driving motor is controlled to rotate with the gear, engage the rack pull rod to drive, lift the rack pull rod upward, and slide the isolation cylinder upward;

[0017] S7, the isolation cylinder slides upward inside the extraction cylinder, temporarily closing the collection port, and the filtered and extracted effective components are accumulated inside the extraction box, and the accumulated effective components are pushed upward inside, discharged from the upper end of the extraction cylinder, and flow back through the conical guide plate to slide outward;

[0018] S8. The effective ingredients flow back through the conical guide plate and flow into the collection hopper. Then they are manually cleaned and collected at the discharge plate position, and then slid out to the external position for centralized collection and processing to complete the production.

[0019] Furthermore, a support seat is fixedly connected to one side surface of the movable bracket, a support head is rotatably installed inside the support seat, and the support head is fixedly connected to the bottom surface of the extraction cylinder. By installing the support head on the support seat, the extraction cylinder can be supported and limited, thereby ensuring the stability of the rotation adjustment and improving safety of use.

[0020] Furthermore, a driven gear ring is fixedly connected to the outer surface of the extraction cylinder, and the driven gear ring is located at the bottom of the box.

[0021] Furthermore, a rotating motor is fixedly installed on one side of the movable bracket, and a driving gear is installed on one end of the rotating motor. The driving gear is meshed with one side of the driven gear ring. The driving gear is installed by the rotating motor, thereby meshing the gear ring, and the extraction cylinder can be rotated, which is convenient for active filtration, efficient and stable, and conducive to control and use.

[0022] Furthermore, an oscillating telescopic rod is fixedly installed on the bottom of the box, and one end of the oscillating telescopic rod is fixedly connected to the surface of one end of the movable bracket. The movable bracket is connected by the oscillating telescopic rod, which can be telescopically controlled to oscillate up and down to avoid blockage and improve extraction performance and efficiency.

[0023] Furthermore, a feed pipe is fixedly connected to one end surface of the box body, and the feed pipe is located at the bottom of the box body.

[0024] Furthermore, a long through groove is provided on one side of the box body, and an overflow pipe is slidably installed inside the long through groove. By connecting the feed pipe and the overflow pipe, it is convenient to replenish the extraction liquid, which is conducive to continuous filtration and extraction with high efficiency and stability.

[0025] Furthermore, one end of the overflow pipe is fixedly connected to a sealing plate, the sealing plate is slidably connected to one side of the long through groove, and the sealing plate is slidably installed on the inner wall surface of the box body.

[0026] Furthermore, an adjustable telescopic rod is fixedly installed on one side of the overflow pipe, and the adjustable telescopic rod is fixedly installed on the outer surface of the box body. The sealing plate and the adjustable telescopic rod are installed through the overflow pipe, and the height can be adjusted up and down by telescopic control, which is beneficial to control the overflow height, improve the stability of use, and facilitate combined adjustment.

[0027] Compared with the prior art, the advantages of the present invention are:

[0028] (1) This solution installs an extraction cylinder inside the box, combined with the extraction box and collection port on the surface, which can be rotated and adjusted for active filtering to ensure efficiency and accuracy. In addition, the isolation cylinder is installed through the internal rack pull rod, which can be uniformly collected and discharged to avoid interference. It is efficient, stable and highly adaptable.

[0029] (2) By installing the support head through the support seat, the extraction cylinder can be supported and limited, ensuring the stability of the rotation adjustment and improving the safety of use.

[0030] (3) By rotating the motor to install the driving gear, the gear ring is engaged, which can drive the extraction cylinder to rotate, making it convenient for active filtration, efficient and stable, and easy to control.

[0031] (4) The movable bracket can be connected by an oscillating telescopic rod, which can be telescopically controlled to oscillate up and down to avoid blockage and improve extraction performance and efficiency.

[0032] (5) By connecting the feed pipe and the overflow pipe, it is convenient to replenish the extraction liquid, which is conducive to continuous filtration and extraction, and is efficient and stable.

[0033] (6) The sealing plate and the adjustable telescopic rod are installed through the overflow pipe, and the height can be adjusted up and down by telescopic control, which is conducive to controlling the overflow height, improving the stability of use, and facilitating combined adjustment. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] Figure 1 It is a schematic diagram of the external three-dimensional structure of the overall structure of the present invention;

[0035] Figure 2 It is a schematic diagram of the planar structure of the present invention;

[0036] Figure 3 It is a partial cross-sectional view of the connection between the extraction cylinder and the extraction box of the present invention;

[0037] Figure 4 It is a three-dimensional schematic diagram of the extraction cylinder and the extraction box of the present invention;

[0038] Figure 5 It is a partial cross-sectional view of the connection between the mounting frame and the collecting bucket of the present invention;

[0039] Figure 6 It is a partial structural diagram of the movable support connection of the present invention;

[0040] Figure 7 It is a partial structural diagram of the connection between the fixed cylinder and the telescopic rod of the present invention;

[0041] Figure 8 It is a partial schematic diagram of the overflow pipe connection of the present invention.

[0042] Description of the numbers in the figure:

[0043] 1 box body, 11 sealing hole, 12 extraction cylinder, 13 extraction box body, 14 filter plate, 15 collection port, 16 conical guide plate, 17 mounting frame, 18 rack pull rod, 2 isolation cylinder, 20 sealing cylinder, 21 conical head, 22 collection bucket, 23 circular avoidance hole, 24 discharge plate, 25 drive motor, 26 gear, 3 fixed cylinder, 31 sliding rod, 32 movable bracket, 33 buffer spring, 34 support seat, 35 support head, 36 driven gear ring, 37 rotating motor, 38 driving gear, 39 oscillating telescopic rod, 4 feeding pipe, 41 long through groove, 42 overflow pipe, 43 sealing plate, 44 adjusting telescopic rod. DETAILED DESCRIPTION

[0044] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention; it is obvious that the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments, and all other embodiments obtained by ordinary technicians in this field based on the embodiments of the present invention without making creative work are within the scope of protection of the present invention.

[0045] See also Figure 1 , Figure 2 , Figure 3 and Figure 4 A filtering and extracting device for biomedical production includes a box body 1. A sealing hole 11 is provided at the bottom of the box body 1. An extraction cylinder 12 is rotatably installed inside the sealing hole 11. By connecting the extraction cylinder 12 to the inside of the sealing hole 11, the sealing stability during rotation can be ensured to avoid leakage of the extract. At the same time, it can slide up and down for adjustment, which is conducive to small-amplitude vibration and avoids blockage. It is safe, stable and highly adaptable. The outer surface of the extraction cylinder 12 is fixedly connected to an extraction box body 13. The opening position of the extraction box body 13 is fixedly connected to a filter plate 14. By rotating the extraction cylinder 12 with the extraction box body 13, the filter plate 14 on the surface can be combined to filter and collect the extract into the extraction box body 13, which is convenient and efficient. , can actively contact the extract for collection, convenient operation and use, high adaptability, the outer surface of the extraction cylinder 12 is provided with a collection port 15, and the collection port 15 is provided, so that the extracted substances can be collected into the inside of the extraction cylinder 12, which is convenient for separation and storage and avoids interference. The collection port 15 is located on one side of the inside of the extraction box 13, and a conical guide plate 16 is fixedly connected to one end surface of the extraction cylinder 12, and a mounting frame 17 is fixedly connected to the upper end surface of the box 1, and a rack pull rod 18 is slidably installed in the middle position of the mounting frame 17. The rack pull rod 18 is connected by the mounting frame 17, and can be slid up and down for adjustment, which is convenient for controlling the discharge, has high adaptability and avoids interference, and the rack pull rod 18 is slidably connected to the inside of the extraction cylinder 12;

[0046] See also Figure 2 and Figure 7One end of the rack pull rod 18 is fixedly connected to the isolation cylinder 2, and one end of the isolation cylinder 2 is fixedly connected to the conical head 21. The isolation cylinder 2 is connected by the rack pull rod 18, which will not interfere with the rotation adjustment of the extraction cylinder 12. At the same time, it can be pulled upward for adjustment, and the stored extraction material can be moved upward, so as to discharge the material from the top, which is efficient and stable. During the upward pulling process, the isolation cylinder 2 can temporarily close the collection port 15 to prevent the collected extraction material from entering and entering the bottom position of the isolation cylinder 2, avoiding interference and waste, and being safe and stable. The conical head 21 is fixedly connected to one end of the rack pull rod 18, and a sealing cylinder 20 is fixedly connected to the outer surface of the isolation cylinder 2. By setting the sealing cylinder 20, elastic sealing can be achieved, stability can be improved, gaps can be avoided, and installation and use are facilitated. , and the extract will not leak after entering the extraction cylinder 12. The sealing cylinder 20 is slidably connected to the inner wall surface of the extraction cylinder 12. The inner side of the mounting frame 17 is fixedly connected with a collecting bucket 22. The bottom of the collecting bucket 22 is provided with a circular avoidance hole 23. The circular avoidance hole 23 is sleeved on one end surface of the extraction cylinder 12. One side of the collecting bucket 22 is fixedly connected with a discharge plate 24. The discharge plate 24 is fixedly connected to one side of the mounting frame 17. By setting the collecting bucket 22 and combining the circular avoidance hole 23, the combined installation can be performed without interfering with the rotation adjustment of the extraction cylinder 12. After discharging from the upper end of the extraction cylinder 12, it can enter the collecting bucket 22 to avoid falling. Then, it can be uniformly discharged from the position of the discharge plate 24, which is convenient for manual cleaning and collection, with high adaptability, high efficiency and stability.

[0047] The upper surface of the mounting frame 17 is fixedly connected with a driving motor 25, and a gear 26 is installed at one end of the driving motor 25. The gear 26 meshes with one side of the rack pull rod 18. The gear 26 is installed by the driving motor 25, and the rack pull rod 18 can be rotated to mesh, and the rack pull rod 18 can be driven to slide up and down, which is beneficial to control the isolation cylinder 2 for positioning, which is beneficial to discharging, and has high adaptability. The bottom two ends of the box body 1 are fixedly connected with a fixed cylinder 3, and a sliding rod 31 is slidably installed inside the fixed cylinder 3. A movable bracket 32 ​​is fixedly installed at one end of the sliding rod 31, and a buffer spring 33 is slidably installed at the other end of the sliding rod 31. The buffer spring 33 is slidably installed inside the fixed cylinder 3. The sliding rod 31 is installed by the fixed cylinder 3, so as to connect the buffer spring 33 and the movable bracket 32, and can slide up and down with a small amplitude, which is beneficial to combined positioning. In this way, the extraction cylinder 12 can be pushed to slide up and down, thereby driving the extraction box body 13 and the filter plate 14 to oscillate up and down inside the extraction liquid, avoiding blockage, facilitating the maintenance of the extraction surface, improving the efficiency and stability of continuous production, and facilitating control and use;

[0048] The method for using the extraction device comprises the following steps:

[0049] S1, adding the treated extract into the box 1, controlling the liquid level to be above the extraction box 13, part of the extract will pass through the filter plate 14 into the extraction box 13, and then flow into the extraction cylinder 12 from the collection port 15;

[0050] S2, control the extraction cylinder 12 to rotate inside the box 1, and rotate with the extraction box 13 and the filter plate 14, the filter plate 14 actively impacts the extract, filters and extracts the effective components inside, and the filtered effective components enter the extraction box 13 and continue to accumulate;

[0051] S3, the accumulated effective ingredients enter the extraction cylinder 12 through the collection port 15, gradually accumulate inside the extraction cylinder 12, and are stored at the upper end of the isolation cylinder 2, and continue to rotate for filtering and extraction;

[0052] S4, the sliding rod 31 is supported by the fixed cylinder 3, which can be slidably adjusted, and the internal buffer spring 33 is used for buffering support, the movable bracket 32 ​​is buffered and adjusted, and the connected extraction cylinder 12 is supported and adjusted to perform up and down oscillation adjustment;

[0053] S5, the extraction cylinder 12 oscillates up and down inside the box 1, and brings the extraction box 13 and the filter plate 14 to oscillate up and down in the extraction liquid to assist in cleaning the surface;

[0054] S6, after the filtration and extraction is completed, the driving motor 25 is controlled to rotate with the gear 26, and the rack pull rod 18 is engaged to drive, and the rack pull rod 18 is lifted upward, and the isolation cylinder 2 is driven to slide upward;

[0055] S7, the isolation cylinder 2 slides upward inside the extraction cylinder 12, temporarily closing the collection port 15, and the filtered and extracted effective components are accumulated inside the extraction box 13, and the accumulated effective components are pushed upward inside, discharged from the upper end of the extraction cylinder 12, and flow back through the conical guide plate 16 to slide outward;

[0056] S8. The effective ingredients flow back through the conical guide plate 16 and flow into the collecting hopper 22. Then they are manually cleaned and collected at the position of the discharge plate 24, and then slid out to the external position for centralized collection and processing, thus completing the production.

[0057] See also Figure 2 and Figure 6A support seat 34 is fixedly connected to one side surface of the movable bracket 32, and a support head 35 is rotatably installed inside the support seat 34. The support head 35 is fixedly connected to the bottom surface of the extraction cylinder 12. The support head is installed by the support seat, so that the extraction cylinder can be supported and limited, ensuring the stability of the rotation adjustment and improving the safety of use. The support head 35 rotates inside the support seat 34 to assist in supporting the extraction cylinder 12, thereby improving the stability of the rotation and avoiding the up and down oscillation that can be pushed and adjusted. It is safe, stable and highly adaptable.

[0058] See also Figure 2 and Figure 6 The outer surface of the extraction cylinder 12 is fixedly connected with a driven gear ring 36, and the driven gear ring 36 is located at the bottom of the box body 1. A rotating motor 37 is fixedly installed on one side of the movable bracket 32. A driving gear 38 is installed at one end of the rotating motor 37. The driving gear 38 is meshed with one side of the driven gear ring 36. The driving gear is installed by the rotating motor, thereby meshing the gear ring, and the extraction cylinder can be rotated, which is convenient for active filtration, efficient and stable, and conducive to control and use.

[0059] See also Figure 2 and Figure 8 An oscillating telescopic rod 39 is fixedly installed at the bottom of the box body 1, and one end of the oscillating telescopic rod 39 is fixedly connected to the surface of one end of the movable bracket 32. The movable bracket is connected by the oscillating telescopic rod, and can be telescopically controlled to oscillate up and down to avoid blockage and improve the extraction performance and efficiency. By controlling the extension and retraction of the oscillating telescopic rod 39, the movable bracket 32 ​​can be slid up and down, and the extraction cylinder 12 can be adjusted in combination with the support seat 34, so as to perform up and down oscillation adjustment, which is convenient for combined control and use, avoids filter blockage, and facilitates continuous extraction for production, which is safe and efficient.

[0060] See also Figure 2 and Figure 8 A feed pipe 4 is fixedly connected to the surface of one end of the box body 1, and the feed pipe 4 is located at the bottom of the box body 1. A long through groove 41 is provided on one side of the box body 1, and an overflow pipe 42 is slidably installed inside the long through groove 41. By connecting the feed pipe and the overflow pipe, it is convenient to replenish the extraction liquid, which is beneficial to continuous filtration and extraction, efficient and stable. The feed pipe 4 can be connected to the pipeline to replenish the extraction liquid into the box body 1, which is beneficial to continuous filtration and extraction, and the excess part can flow back from the overflow pipe 42, avoiding waste and pollution of the working environment, which is beneficial to controlling the internal liquid level height, and is also convenient for multiple replenishments, with high adaptability.

[0061] One end of the overflow pipe 42 is fixedly connected to a sealing plate 43, which is slidably connected to one side of the long through groove 41. The sealing plate 43 is slidably installed on the inner wall surface of the box body 1, and one side of the overflow pipe 42 is fixedly installed with an adjustable telescopic rod 44, which is fixedly installed on the outer surface of the box body 1. The sealing plate and the adjustable telescopic rod are installed through the overflow pipe, and the height can be adjusted up and down by telescopic control, which is beneficial to controlling the overflow height, improving the stability of use, and facilitating combined adjustment. When used, the adjustable telescopic rod 44 can be controlled to be extended and retracted, thereby sliding the overflow pipe 42 up and down inside the long through groove 41, and the overflow height can be changed to adjust the internal liquid level, which is beneficial to inspection and maintenance, and also convenient for production control. During the up and down adjustment process, the sealing plate 43 slides up and down against the inner wall surface of the box body 1, and the long through groove 41 can be isolated and sealed to avoid leakage, thereby improving the safety and stability during adjustment, and facilitating combined installation to control production.

[0062] The above is only a preferred specific implementation of the present invention; however, the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical solution and its improved conception of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A filtering and extracting device for biopharmaceutical production, comprising a housing (1), characterized in that: The bottom of the box body (1) is provided with a sealing hole (11), an extraction cylinder (12) is rotatably mounted inside the sealing hole (11), the outer surface of the extraction cylinder (12) is fixedly connected to the extraction box body (13), the opening position of the extraction box body (13) is fixedly connected to a filter plate (14), the outer surface of the extraction cylinder (12) is provided with a collection port (15), the collection port (15) is located on one side of the interior of the extraction box body (13), one end surface of the extraction cylinder (12) is fixedly connected to a conical guide plate (16), the upper end surface of the box body (1) is fixedly connected to a mounting frame (17), a rack pull rod (18) is slidably mounted at the middle position inside the mounting frame (17), and the rack pull rod (18) is slidably connected to the interior of the extraction cylinder (12); One end of the rack pull rod (18) is fixedly connected to an isolation cylinder (2), one end of the isolation cylinder (2) is fixedly connected to a conical head (21), the conical head (21) is fixedly connected to one end of the rack pull rod (18), the outer surface of the isolation cylinder (2) is fixedly connected to a sealing cylinder (20), the sealing cylinder (20) is slidably connected to the inner wall surface of the extraction cylinder (12), the inner side of the mounting frame (17) is fixedly connected to a collecting bucket (22), the bottom of the collecting bucket (22) is provided with a circular avoidance hole (23), the circular avoidance hole (23) is sleeved on one end surface of the extraction cylinder (12), one side of the collecting bucket (22) is fixedly connected to a discharge plate (24), the discharge plate (24) is fixedly connected to one side of the mounting frame (17); A driving motor (25) is fixedly connected to the upper surface of the mounting frame (17), a gear (26) is installed at one end of the driving motor (25), and the gear (26) is meshed with one side of the rack pull rod (18). The two ends of the bottom of the box body (1) are fixedly connected to a fixed cylinder (3), a sliding rod (31) is slidably installed inside the fixed cylinder (3), a movable bracket (32) is fixedly installed at one end of the sliding rod (31), and a buffer spring (33) is slidably installed at the other end of the sliding rod (31), and the buffer spring (33) is slidably installed inside the fixed cylinder (3).

2. A filtering and extracting device for biopharmaceutical production according to claim 1, characterized in that: A support seat (34) is fixedly connected to one side surface of the movable bracket (32), a support head (35) is rotatably mounted inside the support seat (34), and the support head (35) is fixedly connected to the bottom surface of the extraction cylinder (12).

3. A filtering and extracting device for biopharmaceutical production according to claim 1, characterized in that: The outer surface of the extraction cylinder (12) is fixedly connected to a driven gear ring (36), and the driven gear ring (36) is located at the bottom of the box body (1).

4. A filtering and extracting device for biopharmaceutical production according to claim 1, characterized in that: A rotating motor (37) is fixedly mounted on one side of the movable bracket (32), a driving gear (38) is mounted on one end of the rotating motor (37), and the driving gear (38) is meshed with one side of the driven gear ring (36).

5. A filtering and extracting device for biopharmaceutical production according to claim 1, characterized in that: An oscillating telescopic rod (39) is fixedly mounted on the bottom of the box body (1), and a rod head at one end of the oscillating telescopic rod (39) is fixedly connected to a surface at one end of the movable bracket (32).

6. A filtering and extracting device for biopharmaceutical production according to claim 1, characterized in that: A feed pipe (4) is fixedly connected to one end surface of the box body (1), and the feed pipe (4) is located at the bottom of the box body (1).

7. A filtering and extracting device for biopharmaceutical production according to claim 1, characterized in that: A long through groove (41) is provided on one side of the box body (1), and an overflow pipe (42) is slidably mounted inside the long through groove (41).

8. A filtering and extracting device for biopharmaceutical production according to claim 7, characterized in that: One end of the overflow pipe (42) is fixedly connected to a sealing plate (43), the sealing plate (43) is slidably connected to one side of the long through groove (41), and the sealing plate (43) is slidably mounted on the inner wall surface of the box body (1).

9. A filtering and extracting device for biopharmaceutical production according to claim 7, characterized in that: An adjustable telescopic rod (44) is fixedly mounted on one side of the overflow pipe (42); the adjustable telescopic rod (44) is fixedly mounted on the outer surface of the box body (1); The method for using the extraction device comprises the following steps: S1, adding the treated extract into the box (1), controlling the liquid level to be above the extraction box (13), and part of the extract will pass through the filter plate (14) into the extraction box (13), and then flow into the extraction cylinder (12) from the collection port (15); S2, controlling the extraction cylinder (12) to rotate inside the box (1), driving the extraction box (13) and the filter plate (14) to rotate, the filter plate (14) actively impacting the extraction liquid, filtering and extracting the effective components inside, and the filtered effective components enter the extraction box (13) and continue to accumulate; S3, the accumulated effective ingredients enter the extraction cylinder (12) through the collection port (15), gradually accumulate inside the extraction cylinder (12), and are stored at the upper end of the isolation cylinder (2), and are continuously rotated for filtering and extraction; S4, the sliding rod (31) is supported by the fixed cylinder (3) to be slidable and adjustable, and the internal buffer spring (33) is used for buffering support, the movable bracket (32) is buffered and adjusted, and the connected extraction cylinder (12) is supported and adjusted to perform up and down oscillation adjustment; S5, the extraction cylinder (12) oscillates up and down inside the box (1), causing the extraction box (13) and the filter plate (14) to oscillate up and down in the extraction liquid to assist in cleaning the surface; S6, after the filtration and extraction is completed, the driving motor (25) is controlled to rotate with the gear (26), and the rack pull rod (18) is engaged to drive, and the rack pull rod (18) is lifted upward, and the isolation cylinder (2) is driven to slide upward; S7, the isolation cylinder (2) slides upward inside the extraction cylinder (12), temporarily closing the collection port (15), and the filtered and extracted effective components are accumulated inside the extraction box (13), and the accumulated effective components are pushed upward inside, discharged from the upper end of the extraction cylinder (12), and flow back through the conical guide plate (16) to slide outward; S8. The active ingredients flow back through the conical guide plate (16) and flow into the collection bucket (22). They are then manually cleaned and collected at the discharge plate (24), where they are then slid out to an external position for centralized collection and processing, thus completing production.

Citation Information

Patent Citations

  • Filter residue filtering device for biopharmaceuticals

    CN212141736U

  • Artemisia argyi extracting solution filtering equipment

    CN216497902U