Animal experiment platform for simulating microgravity environment

Abstract

The invention discloses an animal experiment platform for simulating a microgravity environment, and the platform comprises a positioning device which is provided with an accommodation space; the plurality of suspension devices are arranged on the periphery of the accommodating space; the suspension device and the positioning device are detachably assembled; the suspension devices are provided with containing spaces, the containing spaces are communicated with the containing spaces, and the containing spaces of every two adjacent suspension devices are also communicated with each other. The power device is detachably connected below the positioning device; the power device is used for driving the positioning device to rotate so as to drive the multiple suspension devices to rotate. According to the invention, a plurality of independent experimental animal accommodating spaces are provided, and a plurality of experimental animal objects can be kept independent from one another and cannot climb or twine one another; meanwhile, the multiple containing spaces are communicated, consistency can be kept in the aspect of environment control, synchronous adjustment of microgravity training research environment conditions is achieved, it is ensured that all experimental animal objects are tested under the same experimental conditions, and finally the purpose of improving the experimental efficiency is achieved.

Description

Technical Field

[0001] The present invention relates to the technical field of animal microgravity experiments, and in particular to an animal experiment platform for simulating a microgravity environment. Background Art

[0002] In life science research, it is often necessary to keep experimental animals in a specific posture for observation, study or handling. Since animals are naturally active and difficult to control, researchers need to use restraints that can limit the body movement of animals to a certain extent to achieve the purpose of controlling animals. In simulated weightlessness research, in order to simulate the effects of microgravity on experimental animals, a specific suspension restraint system is particularly needed.

[0003] At present, the tail suspension model is mostly used in animal experiments simulating microgravity, that is, multiple experimental animals (such as mice) are hung in the same cage after passing metal wires through their tails. Due to the movement of the experimental animals, the ropes of the tail suspension will become entangled with each other and the animals will climb on each other, which is not convenient for real-time collection of animal physiological data and will limit the animals' diet and water intake, ultimately leading to low experimental efficiency.

[0004] In view of this, the existing technology still needs to be improved and developed. Summary of the invention

[0005] In view of the above-mentioned deficiencies in the prior art, an object of the present invention is to provide an animal experiment platform that simulates a microgravity environment, aiming to improve the experimental efficiency.

[0006] The technical solution adopted by the present invention to solve the technical problem is as follows:

[0007] An animal experiment platform simulating a microgravity environment, comprising:

[0008] A positioning device having a receiving space;

[0009] A plurality of suspension devices are arranged at the periphery of the accommodation space; the suspension devices are detachably assembled with the positioning device; the suspension devices have an accommodation space, the accommodation space is connected with the accommodation space, and the accommodation spaces of two adjacent suspension devices are also connected with each other;

[0010] The power device is detachably connected to the bottom of the positioning device; the power device is used to drive the positioning device to rotate, so as to drive the multiple suspension devices to rotate.

[0011] In the animal experiment platform simulating a microgravity environment, the suspension device is in a trapezoidal or fan-shaped shape; a plurality of the suspension devices are arranged around the periphery of the positioning device with the positioning device as the center of the circle.

[0012] The animal experiment platform simulating a microgravity environment, wherein the positioning device comprises:

[0013] Axis of rotation;

[0014] A first rotating disk; one axial end of the rotating shaft is connected to the first rotating disk;

[0015] A second turntable is coaxially arranged below the first turntable; the other axial end of the rotating shaft passes through the second turntable and is detachably connected to the power device;

[0016] The accommodating space is located between the first turntable and the second turntable; the first turntable and the second turntable are both detachably assembled with the suspension device.

[0017] The animal experiment platform simulating a microgravity environment, wherein the suspension device comprises:

[0018] A bracket, detachably assembled with the positioning device;

[0019] A hanging chain assembly is located in the bracket and is detachably connected to the bracket; the hanging chain assembly is used to hang the experimental animal;

[0020] The loading tray is located below the suspension chain assembly and is detachably assembled with the bracket.

[0021] The animal experiment platform simulating a microgravity environment, wherein the support comprises:

[0022] Two supporting frames are arranged relatively tilted;

[0023] A first connecting portion is disposed between the two supporting frames and is detachably connected to the first rotating disk;

[0024] A second connecting portion is disposed between the two supporting frames and is detachably connected to the second rotating disk;

[0025] A support rib, disposed between the two support frames and arranged radially on the outside of the second connection portion;

[0026] The bearing part is arranged between the two supporting frames and is located above the supporting ribs; the bearing part is used for bearing food.

[0027] The animal experiment platform simulating a microgravity environment further comprises:

[0028] The plug-in portion is arranged on the cargo tray; the second connecting portion is provided with at least one plug hole, and the plug-in portion is plugged and matched with the plug hole;

[0029] At least two engaging members are arranged on both sides of the loading tray; the engaging members have downwardly arranged notches, and the notches are used for the supporting frame to be engaged with the engaging members.

[0030] The animal experiment platform simulating a microgravity environment further comprises:

[0031] At least one extension portion is arranged on the top of the loading tray and extends outward to form an inverted L-shaped accommodation space together with the loading tray; the support rib is located in the L-shaped accommodation space

[0032] The animal experiment platform simulating a microgravity environment further comprises:

[0033] The anti-escape device is located above the power device and arranged on the periphery of the multiple suspension devices; the anti-escape device is provided with a mounting hole, and a part of the positioning device passes through the mounting hole and is connected to the power device.

[0034] The animal experiment platform simulating a microgravity environment, wherein the anti-escape device comprises:

[0035] A transparent box having an opening on the top; the plurality of suspension devices are located in the transparent box;

[0036] An upper cover is arranged at the opening and can rotate relative to the transparent box to open and cover the opening;

[0037] The vent assembly is arranged on the transparent box to connect the inside of the transparent box with the outside.

[0038] The animal experiment platform simulating a microgravity environment, wherein the vent assembly comprises:

[0039] A plurality of vent units are arranged in sequence and at intervals along the horizontal direction;

[0040] The vent unit comprises:

[0041] A plurality of ventilation holes are arranged in sequence along the vertical direction; the height of the lowest ventilation hole among the plurality of ventilation holes from the bottom of the transparent box is 1 / 3 of the height of the transparent box.

[0042] Compared with the prior art, the present invention has the following beneficial effects:

[0043] The animal experiment platform simulating a microgravity environment described in the present invention not only provides a plurality of independent experimental animal subject accommodation spaces, but also allows the plurality of experimental animal subjects to remain independent of each other and not climb or entangle with each other; at the same time, the connectivity between the plurality of accommodation spaces can maintain consistency in environmental control (such as airflow, temperature, humidity, etc.), thereby achieving synchronous regulation of environmental conditions for microgravity training research, ensuring that each experimental animal subject is tested under the same experimental conditions, and ultimately achieving the purpose of improving experimental efficiency and experimental accuracy. BRIEF DESCRIPTION OF THE DRAWINGS

[0044] Figure 1 This is a schematic diagram of the overall structure of the animal experiment platform for simulating a microgravity environment according to the present invention;

[0045] Figure 2 A reference diagram of the use state of a plurality of suspension devices in the present invention, with the positioning device as the center of the circle and arranged around the periphery of the positioning device;

[0046] Figure 3 It is a schematic diagram of the structure of the positioning device described in the present invention;

[0047] Figure 4 is a schematic structural diagram of the bracket in the present invention when it is not assembled with the cargo tray;

[0048] Figure 5 It is a schematic diagram of the structure when the bracket and the cargo tray of the present invention are assembled;

[0049] Figure 6 It is a schematic diagram of the structure of the cargo tray of the present invention;

[0050] Figure 7 It is a schematic diagram of the structure when the plug-in portion and the second connecting portion of the present invention are plugged in and matched;

[0051] Figure 8 is a schematic structural diagram of the second connecting portion in the present invention;

[0052] Fig. 9 It is a structural schematic diagram of the transparent box body described in the present invention;

[0053] Fig.10 It is a schematic diagram of the distribution structure of the mounting holes on the transparent box body in the present invention;

[0054] Fig.11 It is a schematic diagram of the structure of the upper cover in the present invention;

[0055] Fig.12 It is a schematic structural diagram of the suspension chain assembly described in the present invention.

[0056] The numbers in the figure are as follows: 1-positioning device; 10-accommodating space; 11-rotating axis; 12-first turntable; 13-second turntable; 100-handle; 2-power device; 3-suspension device; 31-bracket; 311-first connecting part; 312-second connecting part; 3120-insertion hole; 3121-connecting plate; 3122-upward part; 313-support rib; 314-bearing part; 315-support frame; 316-partition; 32-suspension chain assembly; 320-pocket; 321-security clothes; 322-chain; 33-carrying tray; 331-tray body; 332-baffle; 333-filter plate; 4-plug-in part; 5-clamping piece; 6-extension part; 7-anti-escape device; 70-installation hole; 71-transparent box; 72-upper cover; 721-cover body; 73-vent assembly. DETAILED DESCRIPTION

[0057] In order to make the purpose, technical solution and effect of the present invention clearer and more specific, the present invention is further described in detail with reference to the accompanying drawings and examples. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0058] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first" and "second" are used only for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the present invention, unless otherwise specified, "multiple" means two or more.

[0059] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0060] The present invention provides an animal experiment platform for simulating a microgravity environment, such as Figure 1As shown, the animal experiment platform for simulating a microgravity environment includes a positioning device 1, a power device 2 and a plurality of suspension devices 3; the positioning device 1 has a receiving space 10 (such as Figure 3 As shown); a plurality of suspension devices 3 are arranged on the periphery of the accommodating space 10; the suspension device 3 is detachably assembled with the positioning device 1; the suspension device 3 has a accommodating space, the accommodating space is connected with the accommodating space 10, and the accommodating spaces of two adjacent suspension devices 3 are also connected with each other; the power device 2 is detachably connected to the bottom of the positioning device 1; the power device 2 is used to drive the positioning device 1 to rotate, so as to drive the plurality of suspension devices 3 to rotate.

[0061] Specifically, the positioning device 1 is used to position a plurality of suspension devices 3, and assemble the suspension devices 3 with the power device 2, so that the driving force generated by the power device 2 can be transmitted through the positioning device 1 to the suspension device 3, thereby realizing the rotation of the suspension device 3. When the power device 2 is started, the positioning device 1 drives the suspension device 3 to rotate, thereby providing a 1G hypergravity state for experimental animals, which is used for microgravity training research before the animals go into space.

[0062] The suspension device 3 is used to simulate the whole-body and long-term suspension of rodent experimental animals (such as mice) during weightlessness training; the accommodation space is used to accommodate experimental animals; each of the suspension devices 3 can hang an experimental animal, so when conducting microgravity training research, experimental animals can be hung one by one in multiple suspension devices 3, so that multiple experimental animals are positioned above the power device 2; based on the accommodation and isolation functions of the suspension device 3 itself, the periphery of the positioning device 1 is divided into multiple independent experimental units by multiple suspension devices 3, each experimental unit can be equipped with a mouse or rat, and multiple experimental units remain independent of each other, so that the experimental animals in multiple experimental units will not climb or entangle with each other, thereby not affecting the effect of the experiment, improving the accuracy of the experimental results, and achieving the purpose of improving the experimental efficiency.

[0063] At the same time, the positioning device 1 has the accommodating space 10, and the accommodating space of each of the suspension devices 3 is connected to the accommodating space 10, so that multiple suspension devices 3 form a multi-channel suspension system on the periphery of the positioning device 1; the connected multi-channel system can maintain consistency in environmental control (such as airflow, temperature, humidity, etc.), thereby achieving synchronous adjustment of environmental conditions for microgravity training research, ensuring that each experimental subject (mice) is tested under the same experimental conditions, and avoiding the environmental differences caused by a single suspension device 3 from affecting the experimental results.

[0064] Therefore, the animal experiment platform simulating a microgravity environment described in the present invention not only provides a plurality of independent experimental animal subject accommodation spaces, but also allows the plurality of experimental animal subjects to remain independent of each other and not climb or entangle with each other; at the same time, the connectivity between the plurality of accommodation spaces can maintain consistency in environmental control (such as airflow, temperature, humidity, etc.), thereby achieving synchronous adjustment of environmental conditions for microgravity training research, ensuring that each experimental animal subject is tested under the same experimental conditions, and ultimately achieving the purpose of improving experimental efficiency and experimental accuracy.

[0065] In one embodiment of the present invention, Figure 2 As shown, multiple suspension devices 3 are evenly arranged around the periphery of the positioning device 1, ensuring that the multiple suspension devices 3 can maintain a specific geometric distribution or equilibrium state. In rotation or microgravity simulation, the uniform arrangement of multiple suspension devices 3 can improve the overall stability and experimental accuracy of the animal experimental platform simulating a microgravity environment.

[0066] In one embodiment of the present invention, the suspension device 3 is in a trapezoidal or fan-shaped shape, and a plurality of the suspension devices 3 are arranged around the periphery of the positioning device 1 with the positioning device 1 as the center.

[0067] Specifically, when the suspension device 3 is designed to be a trapezoid, and the upper base of the suspension device 3 is arranged inward (i.e., toward the positioning device 1), and the lower base of the suspension device 3 is arranged outward; multiple suspension devices 3 are arranged in a circular shape along the circumferential direction on the periphery of the positioning device 1 with the positioning device 1 as the center of the circle.

[0068] The suspension device 3 is arranged on the periphery of the positioning device 1, and the suspension device 3 is designed to be trapezoidal, which helps to balance the forces between the various suspension devices 3, so that the stress distribution of the entire animal experimental platform is more uniform; this design can reduce the physical interference between the devices, ensure that the experimental animal objects in each suspension device 3 are subjected to relatively uniform forces, and avoid the influence of asymmetric force fields on the experimental results. When multiple suspension devices 3 rotate, the trapezoidal structural design of the suspension device 3 can improve the overall stability of the animal experimental platform, reduce vibration or imbalance during the rotation process, and thus ensure that the suspended experimental animal objects maintain relatively stable movement under 1G microgravity in a simulated microgravity environment.

[0069] At the same time, the trapezoidal structure of the suspension device 3 enables each suspension device 3 to be arranged more compactly in space, making full use of the space around the positioning device 1; this can reduce the occupied area of ​​multiple suspension devices 3, while being able to accommodate more experimental objects and improve experimental efficiency.

[0070] like Figure 3As shown, the positioning device 1 includes a rotating shaft 11, a first turntable 12 and a second turntable 13; one axial end of the rotating shaft 11 is connected to the first turntable 12; the second turntable 13 is coaxially arranged below the first turntable 12; the other axial end of the rotating shaft 11 passes through the second turntable 13 and is detachably connected to the power device 2; the accommodating space 10 is located between the first turntable 12 and the second turntable 13; the first turntable 12 and the second turntable 13 are both detachably assembled with the suspension device 3.

[0071] Specifically, the first turntable 12, the second turntable 13 and the rotating shaft 11 are all coaxially arranged; the first turntable 12 and the second turntable 13 are distributed up and down, and the central axis of the rotating shaft 11 is arranged in the vertical direction; the upper end of the rotating shaft 11 is connected to the first turntable 12, and the lower end of the rotating shaft 11 passes through the second turntable 13 and is detachably connected to the power device 2.

[0072] Each of the suspension devices 3 is detachably assembled with the first turntable 12 and the second turntable 13. When the positioning device 1 is removed from the power device 2, the positioning device 1 and the plurality of suspension devices 3 can be separated from the power device 2 as a whole. Based on this, several combination units formed by positioning devices 1 and suspension devices 3 can be prepared in advance, and the combination unit includes a positioning device 1 and a plurality of suspension devices 3; after completing the microgravity experiment on a batch of experimental animal subjects, the positioning device 1 can be directly removed, and the combination unit can be replaced to conduct the microgravity experiment on the next batch of experimental animal subjects, thereby further improving the experimental efficiency.

[0073] Since the assemblies between the suspension device 3 and the first turntable 12 and the second turntable 13 are all detachable, one of the suspension devices 3 can be replaced separately to replace the experimental animal object.

[0074] In one embodiment of the present invention, there are six suspension devices 3, that is, the six suspension devices 3 are evenly arranged around the periphery of the positioning device 1 with the positioning device 1 as the center; when conducting a microgravity experiment, six experimental animal objects can be suspended and positioned at the same time, thereby improving research efficiency.

[0075] In one embodiment of the present invention, the suspension device 3 is in an isosceles trapezoidal shape. When a plurality of suspension devices 3 are arranged around the periphery of the first turntable 12 and are all detachably connected to the first turntable 12, an installation position can be formed on the first turntable 12 between the plurality of suspension devices 3.

[0076] In one implementation of this embodiment, Figure 3As shown, a handle 100 is provided on the top of the first turntable 12, and the handle 100 is located in the installation position; then, after the positioning device 1 is removed from the power device 2, the handle 100 is pulled to separate the combined unit from the power device 2, so as to replace the next combined unit.

[0077] like Figure 5 and Fig.12 As shown, the suspension device 3 includes a bracket 31, a hanging chain assembly 32 and a loading tray 33; the bracket 31 is detachably assembled with the positioning device 1; the hanging chain assembly 32 is located in the bracket 31 and is detachably connected to the bracket 31; the hanging chain assembly 32 is used to hang experimental animals; the loading tray 33 is located below the hanging chain assembly 32 and is detachably assembled with the bracket 31.

[0078] Specifically, the loading tray 33 is used to carry the excrement of the experimental animal subjects, and is also used to carry the food that the experimental animal subjects leak when eating; the loading tray 33 and the bracket 31 are both isosceles trapezoidal.

[0079] like Figure 4 and Figure 5 As shown, the bracket 31 includes a first connecting portion 311, a second connecting portion 312, a supporting rib 313, a bearing portion 314 and two supporting frames 315; the two supporting frames 315 are arranged at an angle relative to each other; the first connecting portion 311 is arranged between the two supporting frames 315 and is detachably connected to the first turntable 12; the second connecting portion 312 is arranged between the two supporting frames 315 and is detachably connected to the second turntable 13; the supporting rib 313 is arranged between the two supporting frames 315 and is radially arranged on the outside of the second connecting portion 312; the bearing portion 314 is arranged between the two supporting frames 315 and is located above the supporting rib 313; the bearing portion 314 is used to bear food.

[0080] Specifically, the first connecting portion 311 and the second connecting portion 312 are both isosceles trapezoidal structures; the first connecting portion 311 and the second connecting portion 312 are both located between the two support frames 315 and are both close to the same end of the support frame 315 (the end of the support frame 315 close to the positioning device 1), thereby connecting and supporting the two support frames 315 from one side of the positioning device 1, and forming the upper base of the isosceles trapezoidal structure; the supporting rib 313 is located between the two support frames 315 and is close to the outer end of the support frame 315, thereby connecting and supporting the two support frames 315 from the side away from the positioning device 1, and forming the lower base of the isosceles trapezoidal structure; then, the two support frames 315, the first connecting portion 311, the second connecting portion 312 and the supporting rib 313 are mutually connected, so that the bracket 31 forms an isosceles trapezoidal structure. The bearing portion 314 is between the two support frames 315 and close to the outer ends of the support frames 315, so as to support the two support frames 315 while bearing food, and position the bracket 31 in an isosceles trapezoidal appearance.

[0081] It should be noted that the downward projection of the carrying portion 314 in the vertical direction at least partially overlaps with the downward projection of the loading tray 33 in the vertical direction, so that food missed by the experimental animal subjects when eating can be caught by the loading tray 33, thereby preventing food residues from contaminating the experimental environment.

[0082] like Figure 5 and Figure 6 As shown, the loading tray 33 includes a tray body 331 , a baffle 332 and a filter plate 333 ; the baffle 332 is disposed on the tray body 331 , and the filter plate 333 is mounted on the baffle 332 .

[0083] Specifically, the baffle 332 is used to divide the tray body 331 into two areas; one area corresponds to the filter plate 333 and is used to receive objects that fall through the filter plate 333; the other area corresponds to the bearing portion 314 and is used to receive missed food residues. The filter plate 333 is located below the suspended experimental animal object and receives the excrement of the experimental animal object.

[0084] like Fig.12 As shown, the hanging chain assembly 32 includes a restraining garment 321 and a plurality of chains 322; the restraining garment 321 is wrapped around the abdomen of the experimental animal to fix the experimental animal; one end of the chain 322 is connected to the restraining garment 321, and the other end is suspended on the supporting frame 315. By adjusting the length of the chain 322, the experimental animal can be suspended in the placement cavity to facilitate subsequent experiments.

[0085] The restraint garment 321 is in an I-shape and made of a flexible material to ensure a gentle and soft restraint process for the experimental animal; the chain 322 is made of a metal material. The restraint garment 321 is also provided with a pocket 320, which is used to place an experimental sensor for detecting data of the experimental animal.

[0086] Specifically, when conducting an experiment, the experimental sensor is first placed in the pocket 320, and then the restraining garment 321 is used to firmly wrap the experimental animal to prevent the experimental animal from falling during the experiment, and then the experiment can be conducted. The experimental sensor can be a photoelectric sensor, a light-sensitive sensor, a thermistor sensor, etc., so as to detect various vital sign parameters of the experimental animal (vital sign parameters include but are not limited to heart rate or blood pressure) through the experimental sensor.

[0087] The pocket 320 can be arranged on the outside of the restraining garment 321 to facilitate the fixing of the experimental sensor to prevent the experimental sensor from falling during the experiment; the pocket 320 can also be arranged on the outside of the restraining garment 321 to facilitate the replacement and maintenance of the experimental sensor. In actual use, the arrangement position of the pocket 320 on the restraining garment 321 can be arranged according to the experimental requirements.

[0088] like Figure 5 and Figure 6 As shown, the animal experiment platform for simulating a microgravity environment further includes a plug-in portion 4 and at least two engaging members 5; the plug-in portion 4 is arranged on the object tray 33; at least one plug hole 3120 (such as Figure 8 As shown), the plug-in portion 4 is plugged into and matched with the plug hole 3120 (as shown Figure 7 The engaging member 5 is disposed on both sides of the cargo tray 33; the engaging member 5 has a downwardly arranged notch, and the notch is used for the support frame 315 to be inserted into the engaging member 5.

[0089] The loading tray 33 is in an isosceles trapezoidal shape, and the engaging parts 5 are distributed on the two sides of the loading tray 33; the plug-in part 4 cooperates with the plug hole 3120, and after being inserted into the plug hole 3120, it is limited by the plug hole 3120; the engaging part 5 cooperates with the support frame 315, so that the support frame 315 can be inserted into the engaging part 5 from the notch from the bottom to the top, thereby engaging with the engaging part 5. Due to the setting of the notch, when the loading tray 33 is pushed upward with force, the loading tray 33 can be separated from the support frame 315 near the engaging part 5, and then the loading tray 33 is moved outward, so that the plug-in part 4 can be pulled out from the plug hole 3120, and finally the loading tray 33 and the support frame 315 are separated, and then the loading tray 33 can be replaced or cleaned.

[0090] Therefore, in the present invention, through the cooperation between the plug-in portion 4 and the plug hole 3120 on the second connecting portion 312, and the cooperation between the locking member 5 and the supporting frame 315, the positioning of the loading tray 33 on the supporting frame 315 and the removal of the loading tray 33 from the supporting frame 315 are achieved.

[0091] The support frame 315 includes a U-shaped frame; the opening of the U-shaped frame is arranged toward the positioning device 1; the two side edges of the U-shaped frame are distributed up and down, and the side edge located at the bottom cooperates with the notch to achieve the insertion into the engaging member 5 or the detachment from the engaging member 5 from the notch. The second connecting portion 312 and the supporting rib 313 connect the lower side edges of the two U-shaped frames, and the first connecting portion 311 connects the upper side edges of the two U-shaped frames.

[0092] In the two U-shaped frames, a partition 316 (such as Figure 4 and Figure 5 As shown in FIG. 1 , the other U-shaped frame is not provided with a partition plate 316, so that two adjacent suspension devices 3 share a partition plate 316. The partition plate 316 is provided with a through hole to connect the receiving spaces of the two suspension devices 3.

[0093] like Figure 8As shown, the second connection part 312 includes a connection plate 3121 and an upturned part 3122. The connection plate 3121 is detachably connected to the second turntable 13. The upturned part 3122 is arranged on the outside of the connection plate 3121 and is vertically upturned relative to the connection plate 3121. The insertion hole 3120 is located at the connection between the connection plate 3121 and the upturned part 3122. When the plug-in part 4 is inserted into the insertion hole 3120, a part of the plug-in part 4 extends to the top of the connection plate 3121, and the connection plate 3121 limits the plug-in part 4 from the bottom of the plug-in part 4, and the upturned part 3122 limits the plug-in part 4 from the side and top of the plug-in part 4.

[0094] In one embodiment of the present invention, Figure 5 and Figure 6 As shown, the animal experiment platform simulating a microgravity environment also includes at least one extension portion 6, which is arranged on the top of the loading tray 33 and extends outward to form an inverted L-shaped accommodating space 10 together with the loading tray 33; the support rib 313 is located in the L-shaped accommodating space 10.

[0095] Specifically, the extension portion 6 is arranged vertically relative to the loading tray 33 and extends outward in the horizontal direction, thereby forming an inverted L-shaped accommodating space 10 between the loading tray 33; when the plug-in portion 4 is inserted into the plug hole 3120 and the side of the U-shaped frame is inserted into the locking member 5, the support rib 313 is located in the L-shaped accommodating space 10, thereby limiting the support rib 313 from above the support rib 313 through the extension portion 6.

[0096] In this embodiment, on the basis of the mutual cooperation between the plug-in portion 4 and the plug hole 3120, and the support frame 315 and the engaging member 5, the cooperation and limitation of the support rib 313 by the extension portion 6 is added, which not only improves the positioning stability of the carrier tray 33 on the support frame 315, but also ensures that the carrier tray 33 can be smoothly removed from the support frame 315.

[0097] The animal experiment platform simulating microgravity environment also includes an anti-escape device 7, such as Figure 1 As shown, the anti-escape device 7 is located above the power device 2 and is arranged on the periphery of the plurality of suspension devices 3; the anti-escape device 7 is provided with a mounting hole 70 (such as Fig.10 As shown), a portion of the positioning device 1 passes through the mounting hole 70 and is connected to the power device 2.

[0098] Specifically, the mounting hole 70 is used to make way for the positioning device 1; the rotating shaft 11 cooperates with the mounting hole 70, so that the rotating shaft 11 passes through the second rotating disk 13 and then passes through the mounting hole 70 to be connected to the power device 2. The anti-escape device 7 protects the periphery of the suspension device 3, thereby preventing the occurrence of animal escape problems during the experiment.

[0099] like Fig. 9 and Fig.11 As shown, the anti-escape device 7 includes a transparent box 71, an upper cover 72 and a vent assembly 73; the top of the transparent box 71 has an opening; the multiple suspension devices 3 are located in the transparent box 71; the upper cover 72 is arranged at the opening and can be rotated relative to the transparent box 71 to open and cover the opening; the vent assembly 73 is arranged on the transparent box 71 to connect the inside of the transparent box 71 with the outside.

[0100] Specifically, the transparent box 71 protects the suspension device 3 while allowing the staff to see at a glance the status of the experimental animals suspended in the suspension device 3, which is convenient for real-time observation and recording of the status of the experimental animals during the microgravity experiment. The upper cover 72 is used to open and close the opening to release and enclose the experimental animals. The vent assembly 73 is used to connect the inside of the transparent box 71 with the outside, so as to supply air to the transparent box 71 and prevent the animals from escaping while meeting the ventilation needs of the experimental animals.

[0101] The vent assembly 73 includes a plurality of vent units, which are arranged in sequence along the horizontal direction; the vent unit includes a plurality of vents, which are arranged in sequence along the vertical direction; the height of the lowest vent among the plurality of vents from the bottom of the transparent box 71 is 1 / 3 of the height of the transparent box 71.

[0102] Specifically, the plurality of vents in the vent unit are arranged vertically, which allows airflow to pass through areas at different heights, forming air exchange in the up-down direction and covering the entire space; this allows air to flow not only in the horizontal direction, but also to circulate from bottom to top or from top to bottom, which helps to eliminate the accumulation of heat, moisture and harmful gases in the transparent box 71 and keep the air fresh. At the same time, the vents arranged vertically in the vent unit allow airflow to diffuse in the vertical direction, which helps to evenly distribute temperature and humidity; especially in a closed space, hot air usually rises, while cold air sinks, and vertical vents can help adjust the temperature and humidity of areas at different heights to prevent local overheating or overhumidification.

[0103] The height of the lowest vent hole among the multiple vent holes from the bottom of the transparent box 71 is 1 / 3 of the height of the transparent box 71, which can make the vent hole closer to the animal activity area and not be arranged at the bottom of the transparent box 71. This position can effectively guide the airflow through the environment where the animal is located, ensure that the air flows in the entire space, enable the animal to breathe fresh air, avoid air stagnation or local hypoxia, and prevent small animals that are good at climbing or jumping from escaping through the vent holes.

[0104] At the same time, the height of the lowest vent hole among the multiple vent holes from the bottom of the transparent box 71 is 1 / 3 of the height of the transparent box 71, which can avoid structural instability or strength reduction caused by opening holes at the bottom or top, and will not affect the overall stability of the anti-escape device 7.

[0105] In one embodiment of the present invention, the lengths of the four sides of the transparent box 71 are all 675 mm, and the heights are all 280 mm; the diameter of the vent hole is 5 mm; the bottom of the transparent box 71 is a square with a side length of 675 mm; the diameter of the mounting hole 70 is 350 mm, which can ensure the passage of the rotating shaft 11 and avoid interference with the rotation of the rotating shaft 11, and can also ensure the strength of the bottom of the transparent box 71. Fig.11 As shown, the upper cover 72 includes two cover bodies 721, which are symmetrically arranged and are both rotatably connected to the transparent box body 71; the length of the cover body 721 is 675 mm and the width is 337.5 mm.

[0106] The power device 2 includes a driver and a motor; the motor is connected to the positioning device 1 and the driver respectively. Specifically, the motor is connected to the rotating shaft 11, and the driver can control the rotating shaft 11 to rotate through the motor.

[0107] The model of the driver is HB808C, the working voltage adopts a DC input voltage of 24VDC~80VDC, the maximum continuous output current is 8.0A, and the maximum peak current is 13A; the driver can also accept differential and single-ended pulse / direction instructions, and has three control modes of position / speed / torque.

[0108] The motor adopts a 2-phase stepper motor; the torque of the motor is 2.2N, the input voltage is 12-60VDC, the rated current is 3.5A / PH, the step angle is 1.8°, the phase resistance is 0.40Ω / PH, the phase inductance is 1.55mH / PH, the maximum speed is 3000rpm, the rated speed is 1000prm, and the moment of inertia is 450g·cm 2 .

[0109] The power device 2 also includes a housing and a display, wherein the motor and the driver are both arranged in the housing; the display is arranged on the housing and is used to connect with the experimental sensor so as to display the data detected by the experimental sensor. The display has a control button for starting and stopping the motor to control the start and stop of the rotation of the suspension device 3.

[0110] The animal experiment platform simulating a microgravity environment also includes a power supply and a controller, and the controller is connected to the power device 2 and the power supply respectively. The controller adopts STM32F429 main control, 5VDC power input, clock 168MHz, flash memory 1MB, memory 8MB, 256B external EEPROM, and 32MB external SDRAM.

[0111] In summary, the present invention provides an animal experiment platform for simulating a microgravity environment, which includes: a positioning device having a containing space; a plurality of suspension devices arranged at the periphery of the containing space; the suspension device and the positioning device are detachably assembled; the suspension device has a containing space, the containing space is connected to the containing space, and the containing spaces of two adjacent suspension devices are also connected to each other; a power device is detachably connected to the bottom of the positioning device; the power device is used to drive the positioning device to rotate, so as to drive the plurality of suspension devices to rotate. The animal experiment platform for simulating a microgravity environment described in the present invention not only provides a plurality of independent experimental animal object containing spaces, but also a plurality of experimental animal objects remain independent from each other, and will not climb or entangle with each other; at the same time, the connection between the plurality of containing spaces can maintain consistency in environmental control (such as airflow, temperature, humidity, etc.), thereby realizing the synchronous adjustment of the environmental conditions of microgravity training research, ensuring that each experimental animal object is tested under the same experimental conditions, and finally achieving the purpose of improving experimental efficiency and experimental accuracy.

[0112] Those skilled in the art will readily appreciate other embodiments of the present invention after considering the specification and practicing the schemes disclosed herein. The present invention is intended to cover any variations, uses or adaptations of the present invention that follow the general principles of the present invention and include common knowledge or customary techniques in the art that are not disclosed in this scheme. The description and examples are to be regarded as exemplary only, and the true scope and spirit of the present invention are indicated by the claims.

Claims

1. An animal experiment platform simulating a microgravity environment, characterized in that: It includes: A positioning device having a receiving space; A plurality of suspension devices are arranged at the periphery of the accommodation space; The suspension device and the positioning device are detachably assembled; The suspension device has a receiving space, the receiving space is connected to the accommodating space, and the receiving spaces of two adjacent suspension devices are also connected to each other; The power device is detachably connected to the bottom of the positioning device; the power device is used to drive the positioning device to rotate, so as to drive the multiple suspension devices to rotate.

2. The animal experiment platform for simulating microgravity environment according to claim 1, characterized in that: The suspension device is in a trapezoidal or fan-shaped shape; a plurality of the suspension devices are arranged around the periphery of the positioning device with the positioning device as the center of the circle.

3. The animal experiment platform for simulating microgravity environment according to claim 1, characterized in that: The positioning device comprises: Axis of rotation; A first rotating disk; one axial end of the rotating shaft is connected to the first rotating disk; A second turntable is coaxially arranged below the first turntable; the other axial end of the rotating shaft passes through the second turntable and is detachably connected to the power device; The accommodating space is located between the first turntable and the second turntable; the first turntable and the second turntable are both detachably assembled with the suspension device.

4. The animal experiment platform for simulating microgravity environment according to claim 3, characterized in that: The suspension device comprises: A bracket, detachably assembled with the positioning device; A hanging chain assembly is located in the bracket and is detachably connected to the bracket; the hanging chain assembly is used to hang the experimental animal; The loading tray is located below the suspension chain assembly and is detachably assembled with the bracket.

5. The animal experiment platform for simulating microgravity environment according to claim 4, characterized in that: The support comprises: Two supporting frames are arranged relatively tilted; A first connecting portion is disposed between the two supporting frames and is detachably connected to the first rotating disk; A second connecting portion is disposed between the two supporting frames and is detachably connected to the second rotating disk; A support rib, disposed between the two support frames and arranged radially on the outside of the second connection portion; The bearing part is arranged between the two supporting frames and is located above the supporting ribs; the bearing part is used for bearing food.

6. The animal experiment platform for simulating microgravity environment according to claim 5, characterized in that: It also includes: The plug-in portion is arranged on the cargo tray; the second connecting portion is provided with at least one plug hole, and the plug-in portion is plugged and matched with the plug hole; At least two engaging members are arranged on both sides of the loading tray; the engaging members have downwardly arranged notches, and the notches are used for the supporting frame to be engaged with the engaging members.

7. The animal experiment platform for simulating microgravity environment according to claim 6, characterized in that: It also includes: At least one extension portion is disposed on the top of the loading tray and extends outward to form an inverted L-shaped accommodation space together with the loading tray; the supporting rib is located in the L-shaped accommodation space.

8. The animal experiment platform for simulating microgravity environment according to claim 1, characterized in that: It also includes: The anti-escape device is located above the power device and arranged on the periphery of the multiple suspension devices; the anti-escape device is provided with a mounting hole, and a part of the positioning device passes through the mounting hole and is connected to the power device.

9. The animal experiment platform for simulating microgravity environment according to claim 8, characterized in that: The anti-escape device comprises: A transparent box having an opening on the top; the plurality of suspension devices are located in the transparent box; An upper cover is arranged at the opening and can rotate relative to the transparent box to open and cover the opening; The vent assembly is arranged on the transparent box to connect the inside of the transparent box with the outside.

10. The animal experiment platform for simulating microgravity environment according to claim 9, characterized in that: The vent assembly comprises: A plurality of vent units are arranged in sequence and at intervals along the horizontal direction; The vent unit comprises: A plurality of ventilation holes are arranged in sequence along the vertical direction; the height of the lowest ventilation hole among the plurality of ventilation holes from the bottom of the transparent box is 1 / 3 of the height of the transparent box.

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