The invention relates to an artificial climate box capable of simulating multiple complex environment conditions, in order to mainly solve the problem of simulating complex environment conditions in space and the air on the ground. The artificial climate box mainly comprises an artificial climate box body, a fluorescent lamp region, an X-ray radiation region, a high-frequency electromagnetic wave emitting probe, a low-frequency electromagnetic wave emitter, a temperature conservation layer, a box body inner container, a rotatable sample support, a temperature/humidity sensor, an observing window, a control panel, a working indicating lamp, a power supply switch, a power line interface, an artificial climate regulating and controlling region, a CO2 and O2 sensor, an electromagnetic wave sensor, an X-ray sensor, a fixer, a gear drive speed reduction device, a main body support, a rotary shaft, a rotary barrel and the like. The temperature, humidity, electromagnetic radiation and ionizing radiation conditions can be regulated and controlled flexibly by the artificial climate box, and micro gravity and supergravity effects are simulated by the rotary sample support of which the speed can be regulated, and thus the simulation of multiple complex conditions is realized and experiment equipment for environment condition simulation experiment in space and in the air is provided on the ground.