Light distribution module, optical measurement device, sample analyzer and sample analysis method

Abstract

The embodiment of the invention discloses a light distribution module, an optical measurement device, a sample analyzer and a sample analysis method.The light distribution module comprises an optical fiber beam combiner, a light uniformizing part and an optical fiber beam splitter, the optical fiber beam combiner is used for receiving light beams emitted by a light source and transmitting the light beams to the light uniformizing part, the light uniformizing part transmits the light beams to the optical fiber beam splitter, and the optical fiber beam splitter is used for receiving the light beams emitted by the light source; the optical fiber beam splitter can uniformly distribute light beams to each detection assembly of the detection module; the optical fiber beam combiner comprises a plurality of optical fiber monofilaments, the optical fiber monofilaments are combined to form a first light emitting end at the light emitting end of the optical fiber beam combiner, and the optical fiber monofilaments are uniformly distributed in the first light emitting end, so that light beams in the optical fiber monofilaments are uniform, the difference of optical channels is reduced, and the light intensity consistency of the optical channels is ensured; therefore, the accuracy of detection results in the optical measurement device and the sample analyzer and the detection repeatability and stability of the optical measurement device and the sample analyzer are improved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a light distribution module, an optical measuring device, a sample analyzer and a sample analysis method. Background Art

[0002] In today's society where the economy and technology are developing rapidly and human consciousness is significantly improved, life and health issues have gradually become the focus of social attention. With the increase in customer demand for coagulation project diagnosis, the number of sample analyses that hospitals need to complete per day has increased significantly. Therefore, higher requirements are also placed on the number of tests, test items, and test accuracy of the current fully automatic coagulation analyzer.

[0003] As a key measuring device of the fully automatic coagulation analyzer, the optical system directly affects the number of samples that can be detected and the detection accuracy of the instrument. Therefore, in order to improve the number of samples detected, the detection items, and the detection accuracy of the current coagulation analyzer, the optical system must first support multiple channels. However, the increase in detection channels will inevitably increase the differences between channels, and the differences in channels will directly affect the accuracy of the test results, the repeatability and stability of the instrument. Summary of the invention

[0004] The purpose of the present invention is to propose a light distribution module, an optical measuring device, a sample analyzer and a sample analysis method, aiming to solve the problem that the optical system of the existing coagulation analyzer can support multiple channels, but there are differences between the channels, which will affect the accuracy of the test results, the repeatability and stability of the instrument.

[0005] In a first aspect, the present invention provides a light distribution module, the light distribution module includes a fiber optic combiner, a light homogenizer and a fiber optic beam splitter, the fiber optic combiner is used to receive a light beam emitted by a light source and transmit the light beam to the light homogenizer, the light homogenizer can homogenize the light beam and transmit the light beam to the fiber optic beam splitter, the fiber optic beam splitter can evenly distribute the light beam to each detection component of the detection module;

[0006] The optical fiber combiner comprises a plurality of optical fiber filaments. At the light output end of the optical fiber combiner, the optical fiber filaments are combined to form a first light output end, and the optical fiber filaments are evenly distributed among the optical fiber filaments in the first light output end.

[0007] In one embodiment, the light output end of the optical fiber combiner is arranged opposite to the light input end of the light homogenizer, and the light output end of the optical fiber combiner and the light input end of the light homogenizer are arranged at intervals to form a first gap; and / or

[0008] The light output end of the light homogenizer is arranged opposite to the light input end of the optical fiber beam splitter, and the light output end of the light homogenizer is arranged at an interval with the light input end of the optical fiber beam splitter to form a second gap.

[0009] In one embodiment, the first gap is no greater than 3 mm, and the second gap is no greater than 3 mm.

[0010] In one embodiment, at the light input end of the optical fiber combiner, each optical fiber single filament is combined to form a first light input end; wherein the first light input end is combined to form one, and is used to be set corresponding to one light source; or, the first light input end is combined to form a plurality of first light input ends, and is used to be set one by one corresponding to each light source;

[0011] The optical fiber splitter includes a plurality of optical fiber filaments, and at the light input end of the optical fiber splitter, the optical fiber filaments are bundled together to form a second light input end; wherein, the first light output end is bundled together to form one, and the light homogenizer and the second light input end are each provided with one; or, the first light output end is bundled together to form a plurality of optical fiber filaments, and the light homogenizer and the second light input end are each provided with a plurality of optical fiber filaments, and are provided one-to-one with each of the first light output ends.

[0012] In a second aspect, the present invention also provides an optical measuring device, comprising a light source module, a detection module and a light distribution module of any of the above-mentioned embodiments, wherein the detection module comprises a plurality of detection components, the light source module is used to emit a light beam, and the light distribution module is arranged between the light source module and the detection module and is used to evenly distribute the light beam to each of the detection components.

[0013] In one embodiment, the light source module includes a plurality of main light sources, and the light emission wavelengths of the main light sources are different;

[0014] The light source module further includes a secondary light source, the light emission wavelength of the secondary light source is the same as the light emission wavelength of one of the primary light sources, so as to be able to intensify the light emitted by one of the primary light sources.

[0015] In one embodiment, a plurality of auxiliary light sources are provided, and are arranged one-to-one corresponding to a plurality of main light sources, so that each auxiliary light source can intensify the light emitted by each main light source.

[0016] In one embodiment, the detection assembly includes an aperture, a reaction cup, a first light receiver and a second light receiver, the light output end of an optical fiber monofilament in the light distribution module, the aperture, the reaction cup and the first light receiver are spaced apart along a first direction, and the second light receiver is arranged on the side of the reaction cup and avoids the straight line where the first direction is located;

[0017] Wherein, the first light receiver is a transmission photoelectric converter, and the second light receiver is a scattering photoelectric converter.

[0018] In a third aspect, the present invention further provides a sample analyzer, which includes the light distribution module of any one of the above embodiments, or the optical measurement device of any one of the above embodiments.

[0019] In a fourth aspect, the present invention further provides a sample analysis method, which is applied to a sample analyzer, wherein the sample analyzer includes a light source module, a detection module and a light distribution module, wherein the detection module includes a plurality of detection components, and the light distribution module is arranged between the light source module and the detection module, and the light distribution module includes a fiber combiner, a light homogenizer and a fiber splitter, wherein the fiber combiner includes a plurality of optical fiber filaments, and the sample analysis method includes the following steps:

[0020] Providing a light beam to the light input end of the optical fiber combiner through the light source module;

[0021] At the light output end of the optical fiber combiner, the optical fiber single fibers are combined to form a first light output end, and the optical fiber single fibers in the first light output end are evenly distributed, and the light beam emitted by the light source module is received by the optical fiber combiner, and the light beam is transmitted to the light homogenizer;

[0022] The light beam is homogenized by the light homogenizer, and the light beam is transmitted to the optical fiber beam splitter;

[0023] The optical fiber beam splitter is used to evenly distribute the light beam to each of the detection components.

[0024] The embodiments of the present invention have the following beneficial effects:

[0025] The light distribution module, optical measuring device and sample analyzer of the present invention are adopted, and the optical fiber combiner includes multiple optical fiber filaments. At the light output end of the optical fiber combiner, the optical fiber filaments are combined to form a first light output end, and the optical fiber filaments are evenly distributed among the optical fiber filaments in the first light output end, so that the light beam in each optical fiber filament is uniform, so that the uniform light beam can be transmitted to the light homogenizer, thereby improving the uniformity of the light beam after being homogenized by the light homogenizer, so that a more uniform light beam can be transmitted to the optical fiber beam splitter, so that the light beam in each optical fiber filament in the optical fiber beam splitter is uniform, so as to reduce the difference between the optical channels, ensure the consistency of the light intensity between the optical channels, and ensure that the optical fiber beam splitter can evenly distribute the light beam to the detection components of the detection module, thereby increasing the accuracy of the detection results in the optical measuring device and the sample analyzer, as well as the detection repeatability and stability of the optical measuring device and the sample analyzer.

[0026] By adopting the sample analysis method of the present invention, at the light output end of the optical fiber combiner, the optical fiber single fibers are combined to form a first light output end, and the optical fiber single fibers in the first light output end are evenly distributed, so that the light beam in each optical fiber single fiber is uniform, so that the uniform light beam can be transmitted to the light homogenizer, thereby improving the uniformity of the light beam after being homogenized by the light homogenizer, so that a more uniform light beam can be transmitted to the optical fiber beam splitter, so that the light beam in each optical fiber single fiber in the optical fiber beam splitter is uniform, so as to reduce the difference between the optical channels, ensure the consistency of the light intensity between the optical channels, and ensure that the optical fiber beam splitter can evenly distribute the light beam to the detection components of the detection module, thereby increasing the accuracy of the sample analysis results, as well as the detection repeatability and stability of the sample analysis. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0028] in:

[0029] Figure 1 FIG. 1 is a schematic diagram of an optical measurement device in a sample analyzer according to an embodiment.

[0030] Figure 2 for Figure 1 Schematic diagram of the light distribution module in the optical measurement device shown.

[0031] Figure 3 for Figure 2 A side view of the multi-core optical fiber in the optical fiber combiner in the light distribution module shown.

[0032] Figure 4 for Figure 3 A front view of the multi-core optical fiber shown.

[0033] Figure 5 for Figure 1 Schematic diagram of the detection module in the optical measurement device shown.

[0034] Figure 6 for Figure 5 Schematic diagram of the detection components in the detection module shown.

[0035] Figure 7 FIG. 4 is a schematic diagram of an optical measuring device in a sample analyzer according to another embodiment.

[0036] Figure 8 for Figure 7 Schematic diagram of the light distribution module in the optical measurement device shown.

[0037] Fig. 9 FIG. 4 is a schematic diagram of an optical measuring device in a sample analyzer according to another embodiment.

[0038] Fig.10 FIG. 4 is a schematic diagram of an optical measuring device in a sample analyzer according to another embodiment.

[0039] Fig.11 FIG. 4 is a schematic diagram of an optical measuring device in a sample analyzer according to another embodiment.

[0040] Figure numbers: 100, light source module; 110, main light source; 111, first light source; 112, second light source; 113, third light source; 114, fourth light source; 115, fifth light source; 120, auxiliary light source; 121, sixth light source; 122, seventh light source; 130, light source combiner; 140, lens; 150, first filter; 200, light distribution module; 210, fiber combiner; 211, first light input end; 212, first light output end; 220, light homogenizer; 230, fiber beam splitter; 231, second light input end; 232, second light output end; 201, optical fiber monofilament; 300, detection module; 310, detection component; 311, aperture; 312, reaction cup; 313, first light receiver; 314, second light receiver; 315, second filter. DETAILED DESCRIPTION

[0041] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0042] It should be noted that all directional indications in the embodiments of the present invention (such as up, down, left, right, front, back, etc.) are only used to explain the relative position relationship, movement status, etc. between the components under a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indication will also change accordingly.

[0043] In addition, the descriptions of "first", "second", etc. in the present invention are only used for descriptive purposes and cannot be understood as indicating or implying their relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In addition, the technical solutions between the various embodiments can be combined with each other, but they must be based on the ability of ordinary technicians in the field to implement them. When the combination of technical solutions is contradictory or cannot be implemented, it should be deemed that such a combination of technical solutions does not exist and is not within the scope of protection required by the present invention.

[0044] The embodiment of the present invention discloses a sample analyzer, which is used for detecting and analyzing samples such as blood. The sample analyzer is a fully automatic coagulation analyzer, and an optical measuring device is one of the core components of the sample analyzer, so that the sample can be detected and analyzed by an optical method.

[0045] See also Figures 1 to 4 The sample analyzer of this embodiment includes an optical measuring device, which includes a light source module 100, a detection module 300 and a light distribution module 200. The detection module 300 includes a plurality of detection components 310. The light source module 100 is used to emit a light beam. The light distribution module 200 is arranged between the light source module 100 and the detection module 300 and is used to evenly distribute the light beam to each detection component 310, thereby completing the detection and analysis of the sample through the optical measuring device.

[0046] In this embodiment, the light distribution module 200 includes a fiber optic combiner 210, a light homogenizer 220 and a fiber optic beam splitter 230. The fiber optic combiner 210 is used to receive a light beam emitted by a light source and transmit the light beam to the light homogenizer 220. The light homogenizer 220 can homogenize the light beam and transmit the light beam to the fiber optic beam splitter 230. The fiber optic beam splitter 230 can evenly distribute the light beam to each detection component 310 of the detection module 300 to ensure the consistency of each optical channel.

[0047] Furthermore, the optical fiber combiner 210 includes a plurality of optical fiber filaments 201. At the light output end of the optical fiber combiner 210, each optical fiber filament 201 is combined to form a first light output end 212. The optical fiber filaments 201 are evenly distributed in the first light output end 212, so that a uniform light beam can be transmitted to the light homogenizer 220, thereby improving the uniformity of the light beam after being homogenized by the light homogenizer 220, so that a more uniform light beam can be transmitted to the optical fiber splitter 230, so that the light beam in each optical fiber filament 201 in the optical fiber splitter 230 is uniform, so as to reduce the difference between each optical channel, ensure the consistency of light intensity between each optical channel, and ensure that the optical fiber splitter 230 can evenly distribute the light beam to each detection component 310 of the detection module 300, thereby increasing the accuracy of the detection results in the optical measurement device and the sample analyzer, as well as the detection repeatability and stability of the optical measurement device and the sample analyzer. The optical measurement device is an optical detection system with multi-channel detection and low channel difference.

[0048] In one embodiment, see Figure 2 The light output end of the optical fiber combiner 210 and the light input end of the light homogenizer 220 are arranged opposite to each other, and the light output end of the optical fiber combiner 210 and the light input end of the light homogenizer 220 are arranged to form a first gap. The first gap can balance the light intensity of the light beam transmitted between the light output end of the optical fiber combiner 210 and the light input end of the light homogenizer 220, and has a homogenizing effect. Figure 2 , that is, the light homogenizer 220 and the optical fiber combiner 210 are not tightly attached, but there is an air gap of size T1.

[0049] It is understandable that when the light output end of the optical fiber combiner 210 and the light input end of the light homogenizer 220 are arranged in close contact, an uneven light spot will be formed in the process of the light beam being output from the light output end of the optical fiber combiner 210 to the light input end of the light homogenizer 220, thereby affecting the uniformity of the light beam output by the light homogenizer 220. Since there is a first gap between the light output end of the optical fiber combiner 210 and the light input end of the light homogenizer 220 in this embodiment, the setting of the first gap can balance the light intensity of the light beam output from the light output end of the optical fiber combiner 210 to the light input end of the light homogenizer 220, and through the setting of the first gap, the light beam has a certain light beam transmission stroke in the process of being output from the light output end of the optical fiber combiner 210 to the light input end of the light homogenizer 220, so that the light beam has a light homogenization effect during the transmission process, thereby improving the uniformity of the light beam output by the light homogenizer 220.

[0050] Furthermore, in this embodiment, the light output end of the light homogenizer 220 is arranged opposite to the light input end of the optical fiber beam splitter 230, and the light output end of the light homogenizer 220 and the light input end of the optical fiber beam splitter 230 are arranged to form a second gap, and the light intensity of the light beam transmitted between the light output end of the light homogenizer 220 and the light input end of the optical fiber beam splitter 230 can be balanced through the second gap, and a light homogenization effect can be achieved. Figure 2, that is, there is also an air gap of size T2 between the light homogenizer 220 and the optical fiber beam splitter 230 .

[0051] Similarly, it can be understood that when the light output end of the light homogenizer 220 and the light input end of the optical fiber beam splitter 230 are arranged in close contact, an uneven light spot will be formed in the process of the light beam being output from the light output end of the light homogenizer 220 to the light input end of the optical fiber beam splitter 230, thereby affecting the uniformity of the light beam output from the light output end of the optical fiber beam splitter 230. Since there is a second gap between the light output end of the light homogenizer 220 and the light input end of the optical fiber beam splitter 230 in this embodiment, the setting of the second gap can balance the light intensity of the light beam transmitted between the light output end of the light homogenizer 220 and the light input end of the optical fiber beam splitter 230, and the setting of the second gap makes the light beam have a certain light beam transmission stroke in the process of being output from the light output end of the light homogenizer 220 to the light input end of the optical fiber beam splitter 230, so that the light beam has a light homogenization effect during the transmission process, thereby improving the uniformity of the light beam output from the optical fiber beam splitter 230.

[0052] Specifically, in order to avoid the light beam transmission stroke being too long, which causes the light intensity of the light beam to weaken, thereby affecting the number of light channels and the light intensity of the light channels allocated to each detection component 310, the first gap is not greater than 3mm, and the first gap can be selected as 1mm, 1.5mm, 2mm or 3mm, etc., and the second gap is not greater than 3mm, and the second gap can be selected as 1mm, 2mm, 2.3mm or 3mm, etc. By setting the first gap to be no greater than 3mm, and setting the second gap to be within the range of no greater than 3mm, it is possible to ensure that the light beam has a certain light beam transmission stroke and has a uniform light effect, and the light intensity of the light beam will not decay, thereby ensuring the number of light channels and the light intensity of each light channel allocated to each detection component 310, thereby meeting the detection requirements of the detection module 300. In addition, the first gap is set to be no greater than 3mm, and the second gap is set to be no greater than 3mm, which is conducive to the miniaturization assembly of the light distribution module 200.

[0053] Further, the end face size of the light input end of the light homogenizer 220 matches the light passing diameter of the first light output end 212 of the optical fiber combiner 210, and the light passing diameter of the first light output end 212 of the optical fiber combiner 210 is 2.0mm-6.0mm, and the light passing diameter of the first light output end 212 of the optical fiber combiner 210 can be selected as 2.0mm, 2.8mm, 3.6mm, 5.0mm or 6.0mm, etc. The length of the light homogenizer 220 is 25mm-60mm, and further, the length of the light homogenizer 220 is 20mm-80mm, and the length of the light homogenizer 220 can be selected as 20mm, 25mm, 40mm, 60mm or 80mm, etc. The end face size of the light output end of the light homogenizer 220 matches the light passing diameter of the second light input end 231 of the optical fiber beam splitter 230. The light passing diameter of the second light input end 231 of the optical fiber beam splitter 230 is 2.0 mm-6.0 mm. The light passing diameter of the second light input end 231 of the optical fiber beam splitter 230 can be selected as 2.0 mm, 2.8 mm, 3.6 mm, 5.0 mm or 6.0 mm, etc. The light passing diameter of the optical fiber beam splitter 230 and each optical fiber filament 201 in the optical fiber beam splitter 230 is 0.4 mm-1.2 mm. The light passing diameter of the optical fiber beam splitter 230 and each optical fiber filament 201 in the optical fiber beam splitter 230 can be selected as 0.4 mm, 0.6 mm, 0.8 mm, 1.0 mm or 1.2 mm, etc. The light passing diameter of all optical fiber filaments 201 is the same.

[0054] Of course, in other embodiments, the first gap can also be 3mm-5mm, further, the first gap can be selected as 4mm or 5mm, and the second gap can also be 3mm-5mm, further, the second gap can be selected as 4mm or 5mm, and the specific size of the first gap needs to be set according to the cross-sectional size of the light output end of the optical fiber combiner 210 and the cross-sectional size of the light input end of the light homogenizer 220. As the cross-sectional size of the light output end of the optical fiber combiner 210 and the cross-sectional size of the light input end of the light homogenizer 220 increase, the specific size of the first gap also increases, thereby ensuring that the light homogenization ability is sufficient, and the specific size of the second gap needs to be set according to the cross-sectional size of the light output end of the light homogenizer 220 and the cross-sectional size of the light input end of the optical fiber splitter 230. The cross-sectional size of the light input end is selected. As the cross-sectional size of the light output end of the light homogenizer 220 and the cross-sectional size of the light input end of the optical fiber splitter 230 increase, the specific size of the second gap also increases accordingly, thereby ensuring that the light homogenization capability is sufficient. It should be noted that when the specific size of the first gap is greater than 3 mm, the effect of increasing the size of the first gap on the light homogenization capability is weakened. When the specific sizes of the second gaps are both greater than 3 mm, the effect of increasing the size of the second gap on the light homogenization capability is also weakened. By setting the size of the first gap and the size of the second gap within the range, it is possible to avoid causing the light beam to decay during the transmission process of the first gap and the second gap, thereby ensuring that the light intensity of the light beam meets the detection requirements of the detection module 300.

[0055] In one embodiment, the light homogenizer 220 is a columnar structure made of a light-guiding material, and both the light input end and the light output end of the light homogenizer 220 are coated with an anti-reflection film. The anti-reflection film can increase the transmittance of the light beam and reduce the reflectivity of the light beam, thereby reducing the light intensity energy loss of the light beam during transmission.

[0056] In one embodiment, see Figures 2 to 4 , Figures 7 to 11 At the light input end of the optical fiber combiner 210, the optical fiber single fibers 201 are combined to form a first light input end 211. In this embodiment, when the first light input ends 211 are combined to form one, the first light input end 211 can be set corresponding to a light source to receive a light beam emitted by a light source.

[0057] When there are multiple first light input ends 211 combined into a beam, and multiple light sources are also provided, and are provided one-to-one with each light source, then each first light input end 211 can receive a light beam emitted by a light source. Further, there are multiple first light input ends 211 and first light output ends 212. In order to support multiple wavelengths of optical detection, the emission wavelengths of each light source are different. By evenly distributing the optical fiber filament 201 bundle contained in at least one of the first light input ends 211 to each first light output end 212, multi-wavelength distribution of each first light output end 212 can be achieved.

[0058] In one embodiment, see Figures 2 to 4 , Figures 7 to 11 The optical fiber beam splitter 230 includes a plurality of optical fiber filaments 201. At the light input end of the optical fiber beam splitter 230, each optical fiber filament 201 is combined to form a second light input end 231. When the first light output end 212 is combined to form one, each light homogenizer 220 and the second light input end 231 are provided with one. At this time, one first light output end 212 can transmit a light beam to one light homogenizer 220, and one light homogenizer 220 can transmit the light beam to one second light input end 231 after homogenization. When the first light output end 212 is combined to form multiple light beams, each light homogenizer 220 and the second light input end 231 are provided with multiple light homogenizers 220 and are arranged one-to-one with each first light output end 212. At this time, each first light output end 212 can transmit its own light beam to each light homogenizer 220, and each light homogenizer 220 can transmit each light beam to each second light input end 231 after homogenization.

[0059] Furthermore, in the present embodiment, at the light output end of the optical fiber splitter 230, the optical fiber filaments 201 are combined to form a second light output end 232; wherein, they are evenly distributed among the optical fiber filaments 201 at the first light input end 211, evenly distributed among the optical fiber filaments 201 at the second light input end 231, and evenly distributed among the optical fiber filaments 201 at the second light output end 232. By evenly distributing the optical fiber filaments 201, the uniformity of the light beam transmission process can be ensured, thereby ensuring that the light beams output by the optical fiber filaments 201 in the second light output end 232 are uniform and have the same light intensity.

[0060] Specifically, the first light input end 211 and the first light output end 212 are combined to form a plurality of light input ends 211 and the first light output end 212 are combined to form a plurality of light input ends 211 and the light homogenizing element 220 are provided in a one-to-one correspondence with each first light output end 212; the second light input end 231 and the second light output end 232 are combined to form a plurality of light input ends 231 and each second light output end 232 is provided in a one-to-one correspondence with each light homogenizing element 220, and each second light input end 231 corresponds to a plurality of second light output ends 232.

[0061] For further information, see Figure 2 The fiber combiner 210 can be selected as a ZY multi-core fiber combiner 210, the light homogenizer 220 can be selected as an optical integrator rod, and each light homogenizer 220 is arranged in an array, and the fiber splitter 230 can be selected as a YS single-core fiber splitter 230, wherein the Z end of the ZY multi-core fiber combiner 210 is LED-fiber coupled with the light source end, and Z represents the number of branches of the first light input end 211. If the light source has 5 optical path channels, Z is 5, that is, each first light input end 211 is connected to an optical path channel and a light source, and the Z first light input ends 211 are combined into Y first light output ends 212, and Y can be selected as 1, 2, 3, etc.

[0062] Please also read Figure 3 and Figure 4 Each optical fiber filament 201 of the optical fiber combiner 210 is a tiny quartz filament, and each quartz filament is evenly distributed in the Y first light output ends 212, that is, the spacing between each quartz filament and other quartz filaments is the same, and they are arranged in a periodic order, thereby reducing the light intensity difference of each optical fiber filament 201 in the optical fiber splitter 230, and further reducing the channel difference.

[0063] At the same time, the optical fiber filaments 201 in the Z first light input ends 211 and the Y first light output ends 212 of the optical fiber combiner 210 are divided in an average manner. For example, when Z is 5 and Y is 3, the optical fiber combiner 210 is a 5-3 multi-core optical fiber combiner 210, and the five first light input ends 211 (Z1-Z5) each have 60 quartz filaments, so there are a total of 300 quartz filaments, and these 300 quartz filaments need to be divided into three first light output ends 212 (Y1-Y3), then the three first light output ends 212 should be composed of 100 quartz filaments each, and these 100 quartz filaments should come from 20 of each of the five first light input ends 211.

[0064] A light homogenizer 220 is arranged at the first light output end 212 of the fiber combiner 210. The light homogenizer 220 array is composed of Y optical integrating rods of the same size and material. Each optical integrating rod is composed of an optical substrate such as fused quartz, and its end face shape can be hexagonal, circular, triangular or quadrilateral, etc. The function of the light homogenizer 220 is to homogenize the light output from the fiber combiner 210 to avoid the appearance of Gaussian spot, thereby reducing channel differences.

[0065] An optical fiber beam splitter 230 is arranged at the light output end of the light homogenizing element 220. The optical fiber beam splitter 230 is a YS single-core optical fiber beam splitter 230, wherein Y corresponds to the number of the light homogenizing elements 220. If there are three light homogenizing elements 220, the optical fiber beam splitter 230 has three second light input ends 231, and each second light input end 231 is respectively connected to the light output end of each light homogenizing element 220, each second light input end 231 corresponds to a plurality of second light output ends 232, and the number of second light output ends 232 corresponding to each second light input end 231 can be selected to be 24, 28 or 30.

[0066] It can be seen from the above that in this embodiment, the specific arrangement of the light distribution module 200 can have multiple implementations.

[0067] In one embodiment, see Figure 7 and Figure 8 , Fig.11 , the fiber combiner 210 is a 5-1 multi-core fiber combiner 210, that is, the first light input end 211 is combined to form 5, the first light output end 212 is combined to form 1, and the light homogenizer 220 is provided with one, and is arranged corresponding to one first light output end 212, and the fiber splitter 230 is a 1-28 single-core fiber splitter 230, that is, the second light input end 231 is combined to form 1, and the second light output end 232 is evenly split into 28. Among them, the radial cross-section of the light homogenizer 220 is a hexagonal end face, and the extension length of the light homogenizer 220 is 25mm. The first gap T1 between the light output end of the fiber combiner 210 and the light input end of the light homogenizer 220 is 2mm, and the second gap T2 between the light output end of the light homogenizer 220 and the light input end of the fiber splitter 230 is 2mm.

[0068] In another embodiment, see Fig. 9 and Fig.10 , the fiber combiner 210 is a 1-1 multi-core fiber combiner 210, that is, the first light input end 211 is combined to form 1, the first light output end 212 is combined to form 1, the light homogenizer 220 is provided with one, and is arranged corresponding to one first light output end 212, and the fiber splitter 230 is a 1-28 single-core fiber splitter 230, that is, the second light input end 231 is combined to form 1, and the second light output end 232 is evenly split into 28. Among them, the radial cross-section of the light homogenizer 220 is a hexagonal end face, and the extension length of the light homogenizer 220 is 25mm. The first gap T1 between the light output end of the fiber combiner 210 and the light input end of the light homogenizer 220 is 2mm, and the second gap T2 between the light output end of the light homogenizer 220 and the light input end of the fiber splitter 230 is 2mm.

[0069] In one embodiment, see Figure 1 , Figure 7 , Figures 9 to 11 The light source module 100 includes a plurality of main light sources 110 , and the light emission wavelengths of the main light sources 110 are different, so that the light source module 100 can provide light beams with multiple wavelengths.

[0070] In this embodiment, the light source module 100 also includes a secondary light source 120, and the light emission wavelength of the secondary light source 120 is the same as the light emission wavelength of one of the main light sources 110, so that it can complement the light emitted by one of the main light sources 110. When the light intensity of the main light source 110 is insufficient, the secondary light source 120 with the same light emission wavelength can be set to complement the light emitted by the main light source 110, thereby ensuring that the light intensity of the light beam of each wavelength meets the detection requirements.

[0071] Furthermore, in this embodiment, a plurality of auxiliary light sources 120 are provided, and are arranged one-to-one with a plurality of main light sources 110, so that each auxiliary light source 120 can reinforce the light emitted by each main light source 110. By providing a plurality of auxiliary light sources 120, the light emitted by a plurality of main light sources 110 can be reinforced at the same time.

[0072] Specifically, at the light input end of the optical fiber combiner 210, when each optical fiber filament 201 is combined to form a first light input end 211, the light beams emitted by each main light source 110 converge to a first light input end 211, so that a multi-wavelength light beam can be transmitted to a first light input end 211. At the light input end of the optical fiber combiner 210, when each optical fiber filament 201 is combined to form a plurality of first light input ends 211, each first light input end 211 is arranged in a one-to-one correspondence with each main light source 110, and is used to receive the light beam emitted by each main light source 110. At this time, in order to evenly distribute the multi-wavelength light beams of each main light source 110, the optical fiber filament 201 bundle contained in at least one of the first light input ends 211 is evenly distributed to each first light output end 212.

[0073] It is understandable that the increase in detection wavelengths in the optical measurement device will involve problems of wavelength coupling and optical power difference. Since the light source module 100 of this embodiment can reinforce the main light source 110 by setting up the auxiliary light source 120, the problem of optical power difference can be solved. Since the optical fiber filament 201 bundle contained in at least one of the first light input ends 211 in the light source module 100 of this embodiment is evenly distributed to each first light output end 212, the multi-wavelength light beams of each main light source 110 can be evenly distributed to solve the problem of wavelength coupling.

[0074] In this embodiment, the specific arrangement of the light source module 100 may have various implementations.

[0075] In one embodiment, see Figure 1 and Figure 7 The light source module 100 is provided with five optical path channels, each of which is arranged in parallel with each other, and each of the optical path channels is respectively a first optical path, a second optical path, a third optical path, a fourth optical path and a fifth optical path. Five main light sources 110 are correspondingly provided, and are respectively arranged at the initial end of each optical path channel. Each main light source 110 is respectively a first light source 111, a second light source 112, a third light source 113, a fourth light source 114 and a fifth light source 115. Each main light source 110 is a light source in a narrow-band wavelength range, wherein the first optical path includes a first main optical path and a first branch path, the first light source 111 is arranged at the initial end of the first main optical path, the fifth optical path includes a second main optical path and a second branch path, the second light source 112 is arranged at the initial end of the second main optical path, and two auxiliary light sources 120 are correspondingly provided, and are respectively arranged at the first branch path and the fifth branch path.

[0076] Specifically, the first optical path, the second optical path, the third optical path, the fourth optical path and the fifth optical path are arranged in order, the first branch path is arranged perpendicular to the first main optical path, and the fifth branch path is arranged perpendicular to the fifth main optical path. At the same time, a light source combiner 130 is arranged at the intersection of the light beams of the first light source 111 and the sixth light source 121 to combine the light beams emitted by the first light source 111 and the sixth light source 121 into a combined light beam, and a light source combiner 130 is arranged at the intersection of the light beams of the fifth light source 115 and the seventh light source 122 to combine the light beams emitted by the fifth light source 115 and the seventh light source 122 into a combined light beam, and the light beams emitted by the second light source 112, the third light source 113 and the fourth light source 114 are each used as a combined light beam.

[0077] In the beam transmission direction of each combined light beam, a lens 140 and a first filter 150 are respectively arranged in each optical path channel, and the light beam in each optical path channel can be focused by the arrangement of the lens 140. Further, by adjusting the distance between each light source and each lens 140, and adjusting the distance between each lens 140 and the light distribution module 200, the light intensity of the light beams transmitted from each optical path channel to the light distribution module 200 can be balanced, so that the light intensity of each light beam converged to the light distribution module 200 is consistent.

[0078] For example, when the distance from each light source to the lens 140 is 16 mm, the distance from each light source to the light distribution module 200 can be adjusted within the range of 38 mm-42 mm to ensure that the light intensity of each light beam converged from each light source to the light distribution module 200 is consistent.

[0079] In this embodiment, the first light source 111 is an LED with any wavelength in the range of 320nm-350nm. Further, the first light source 111 can be an LED with a wavelength of 320nm, 340nm or 350nm. The second light source 112 is an LED with any wavelength in the range of 385nm-430nm. Further, the second light source 112 can be an LED with a wavelength of 385nm, 405nm or 430nm. The third light source 113 is an LED with any wavelength in the range of 625nm-680nm. Further, the third light source 113 can be selected as an LED with a wavelength of 625nm, 660nm or 680nm; the fourth light source 114 is an LED with any wavelength in the range of 780nm-820nm, and further, the fourth light source 114 can be selected as an LED with a wavelength of 780nm, 810nm or 820nm; the fifth light source 115 is an LED with any wavelength in the range of 565nm-590nm, and further, the fifth light source 115 can be selected as an LED with a wavelength of 565nm, 575nm or 590nm. Among them, the sixth light source 121 and the first light source 111 are LEDs with the same wavelength, so that the sixth light source 121 is used to supplement the light intensity of the first light source 111, and the seventh light source 122 and the fifth light source 115 are LEDs with the same wavelength, so that the seventh light source 122 is used to supplement the light intensity of the fifth light source 115.

[0080] Further, the first filter 150 may be selected as a narrow-band filter, wherein the transmission wavelength range of the first filter 150 corresponding to the first light source 111 is 325nm-355nm, further, the transmission wavelength range of the first filter 150 corresponding to the first light source 111 may be selected as 325nm, 335nm, 345nm or 355nm, etc., the transmission wavelength range of the first filter 150 corresponding to the second light source 112 is 390nm-420nm, further, the transmission wavelength range of the first filter 150 corresponding to the second light source 112 may be selected as 390nm, 400nm, 410nm or 420nm, etc., the transmission wavelength range of the first filter 150 corresponding to the third light source 113 is 640nm-680nm, further, The transmission wavelength range of the first filter 150 corresponding to the third light source 113 can be selected as 640nm, 650nm, 660nm, 670nm or 680nm, etc., the transmission wavelength range of the first filter 150 corresponding to the fourth light source 114 can be selected as 788nm-828nm, further, the transmission wavelength range of the first filter 150 corresponding to the fourth light source 114 can be selected as 788nm, 798nm, 808nm, 818nm or 828nm, etc., the transmission wavelength range of the first filter 150 corresponding to the fifth light source 115 is 560nm-600nm, further, the transmission wavelength range of the first filter 150 corresponding to the fifth light source 115 can be selected as 560nm, 570nm, 580nm, 590nm or 600nm, etc.

[0081] When the light source module 100 is specifically detecting work, each main light source 110 works in sequence in a stroboscopic driving mode in a certain periodic sequence, and the lighting duration of each main light source 110 can be 20ms-50ms, and the lighting duration of each main light source 110 can be selected as 20ms, 25ms or 50ms, etc. Among them, each main light source 110 works in sequence in a stroboscopic driving mode in a certain periodic sequence, which specifically means that if the first light source 111 is lit, the other main light sources 110 are extinguished, and after a lighting duration, the first light source 111 is extinguished, the second light source 112 is lit, and all other main light sources 110 are extinguished, and then the fifth light source 115, the third light source 113, and the fourth light source 114 are lit in sequence. When the fourth light source 114 completes the lighting and extinguishing steps, a stroboscopic cycle is completed. The lighting and extinguishing time of the sixth light source 121 is exactly the same as that of the first light source 111, and the lighting and extinguishing time of the seventh light source 122 is exactly the same as that of the fifth light source 115.

[0082] It is understandable that the purpose of setting the auxiliary light source 120 in the above embodiment is to supplement the main light source 110. Therefore, when the LED light intensity of the main light source 110 is high enough, please refer to Fig.11, the auxiliary light source 120 and the light source combiner 130 in the above embodiment can also be eliminated, thereby reducing the manufacturing cost of the light source module 100.

[0083] In another embodiment, see Fig. 9 The light source module 100 is provided with an optical path channel, which includes a main optical path and four branch optical paths. Each branch optical path is connected to the main optical path and is arranged perpendicular to the extension direction of the main optical path. Under the condition that the light intensity of each main light source 110 is sufficient, the setting of the auxiliary light source 120 can be cancelled to save costs. Each main light source 110 is a first light source 111, a second light source 112, a third light source 113, a fourth light source 114 and a fifth light source 115. The fifth light source 115 is arranged at the initial end of the main optical path. The first light source 111, the second light source 112, the third light source 113 and the fourth light source 114 are arranged in order in each branch optical path. The first light source 111, the second light source 112, the third light source 113 and the fourth light source 114 are arranged in a longitudinal array.

[0084] The first light source 111 is an LED with any wavelength in the range of 385nm-430nm, and further, the first light source 111 can be selected as an LED with a wavelength of 385nm, 405nm or 430nm; the second light source 112 is an LED with any wavelength in the range of 780nm-820nm, and further, the second light source 112 can be selected as an LED with a wavelength of 780nm, 810nm or 820nm; the third light source 113 is an LED with any wavelength in the range of 565nm-590nm, and further, the third light source 113 can be selected as an LED with a wavelength of 565nm, 575nm or 590nm; the fourth light source 114 is an LED with any wavelength in the range of 320nm-350nm, and further, the fourth light source 114 can be selected as an LED with a wavelength of 320nm, 340 or 350nm; the fifth light source 115 is an LED with any wavelength in the range of 625nm-680nm, and further, the fifth light source 115 can be selected as an LED with a wavelength of 625nm, 660nm or 680nm.

[0085] In this embodiment, the driving method of each main light source 110 is the same as that of the previous embodiment. Similarly, at each main light source 110, a lens 140 and a first filter 150 are respectively configured, and the lens 140 is a double convex lens 140, and the first filter 150 is a narrow band filter. Among them, the transmission wavelength range of the first filter 150 corresponding to the first light source 111 is 390nm-420nm, and further, the transmission wavelength range of the first filter 150 corresponding to the first light source 111 can be selected as 390nm, 400nm, 410nm or 420nm, etc., the transmission wavelength range of the first filter 150 corresponding to the second light source 112 is 788nm-828nm, and further, the transmission wavelength range of the first filter 150 corresponding to the second light source 112 can be selected as 788nm, 798nm, 808nm, 818nm or 828nm, etc., and the transmission wavelength range of the first filter 150 corresponding to the third light source 113 is 560nm-600nm, and further, the transmission wavelength range of the first filter 150 corresponding to the third light source 113 can be selected as 788nm, 798nm, 808nm, 818nm or 828nm, etc. 13, the transmission wavelength range of the first filter 150 corresponding to the fourth light source 114 is 325nm-355nm. Further, the transmission wavelength range of the first filter 150 corresponding to the fourth light source 114 can be selected as 325nm, 335nm, 345nm or 355nm. The transmission wavelength range of the first filter 150 corresponding to the fifth light source 115 is 640nm-680nm. Further, the transmission wavelength range of the first filter 150 corresponding to the fifth light source 115 can be selected as 640nm, 650nm, 660nm, 670nm or 680nm.

[0086] In this embodiment, a light source combiner 130 is respectively arranged at the place where each branch light path is connected to the main light path. The light source combiner 130 is a binocular mirror, wherein the light source combiner 130 corresponding to the first light source 111 is used to reflect the light of 405±10nm wavelength to converge to the main light path, while the light of other wavelengths is transmitted to be filtered out, and the light source combiner 130 corresponding to the second light source 112 is used to reflect the light of 405±10nm wavelength to converge to the main light path, while the light of other wavelengths is transmitted to be filtered out, and the light source combiner 130 corresponding to the second light source 112 is used to reflect the light of 405±10nm wavelength to converge to the main light path, while the light of other wavelengths is transmitted to be filtered out, and The light source combiner 130 corresponding to the three light sources 113 is used to reflect light with a wavelength of 800±10nm to converge to the main light path, while light of other wavelengths is transmitted through for filtering and removal. The light source combiner 130 corresponding to the fourth light source 114 is used to reflect light with a wavelength of 575±10nm to converge to the main light path, while light of other wavelengths is transmitted through for filtering and removal. The light source combiner 130 corresponding to the fifth light source 115 is used to reflect light with a wavelength of 340±10nm to converge to the main light path, while light of other wavelengths is transmitted through for filtering and removal.

[0087] In yet another embodiment, see Fig.10 The light source module 100 is provided with four optical path channels, and each optical path channel is a first optical path, a second optical path, a third optical path and a fourth optical path. Four main light sources 110 are provided correspondingly, and are respectively arranged at the initial end of each optical path channel, and the end end of each optical path channel converges to a first light incident end 211 of the light beam combiner. The first optical path, the second optical path, the third optical path and the fourth optical path are arranged in a certain offset angle, and the offset angle between two adjacent optical path channels is 0-45°. Furthermore, the offset angle between two adjacent optical path channels can be selected as 10°, 15°, 20°, 25°, 30°, 35°, 40° or 45°, etc.

[0088] The first light source 111 is an LED with any wavelength in the range of 385nm-430nm. Further, the first light source 111 can be selected as an LED with a wavelength of 385nm, 405nm or 430nm; the second light source 112 is an LED with any wavelength in the range of 565nm-590nm. Further, the second light source 112 can be selected as an LED with a wavelength of 565nm, 575nm or 590nm; the third light source 113 is an LED with any wavelength in the range of 625nm-680nm. Further, the third light source 113 can be selected as an LED with a wavelength of 625nm, 660nm or 680nm; the fourth light source 114 is an LED with any wavelength in the range of 780nm-820nm. Further, the fourth light source 114 can be selected as an LED with a wavelength of 780nm, 810 or 820nm.

[0089] In this embodiment, the driving method of each main light source 110 is the same as the driving method of the previous embodiment. Similarly, at each main light source 110, a lens 140 and a first filter 150 are respectively configured, and the lens 140 is a double convex lens 140, and the first filter 150 is a narrow-band filter. Among them, the transmission wavelength range of the first filter 150 corresponding to the first light source 111 is 390nm-420nm, and further, the transmission wavelength range of the first filter 150 corresponding to the first light source 111 can be selected as 390nm, 400nm, 410nm or 420nm, etc., and the transmission wavelength range of the first filter 150 corresponding to the second light source 112 is 560nm-600nm, and further, the transmission wavelength range of the first filter 150 corresponding to the second light source 112 can be selected as 560nm, 570nm, 580nm, 590nm or 600nm, etc. The transmission wavelength range of the first filter 150 corresponding to the third light source 113 is 640nm-680nm. Further, the transmission wavelength range of the first filter 150 corresponding to the third light source 113 can be selected as 640nm, 650nm, 660nm, 670nm or 680nm, etc. The transmission wavelength range of the first filter 150 corresponding to the fourth light source 114 is 788nm-828nm. Further, the transmission wavelength range of the first filter 150 corresponding to the fourth light source 114 can be selected as 788nm, 798nm, 808nm, 818nm or 828nm, etc.

[0090] As can be seen from the above embodiments, the number of main light sources 110 in the light source module 100 , the multi-wavelength range, and the arrangement of the optical path channels can be adjusted according to the setting requirements of the optical measurement device.

[0091] In one embodiment, see Figure 6 The detection component 310 includes an aperture 311, a reaction cup 312, a first light receiver 313 and a second light receiver 314. The light output end of an optical fiber filament 201 in the light distribution module 200, the aperture 311, the reaction cup 312 and the first light receiver 313 are spaced apart along the first direction. The second light receiver 314 is arranged on the side of the reaction cup 312 and avoids the straight line where the first direction is located.

[0092] In this embodiment, the first light receiver 313 is a transmission photoelectric converter, and the second light receiver 314 is a scattering photoelectric converter, thereby supporting switching between scattering and transmission detection methodologies, or combined detection of scattering and transmission methodologies.

[0093] Specifically, a second filter 315 is also arranged between the first light receiver 313 and the reaction cup 312. The second filter 315 can be selected as a low-pass filter with a cut-off wavelength of 830nm. The low-pass filter is a broadband optical filter that transmits light below the cut-off wavelength and blocks light above the cut-off wavelength. Its function is to remove external stray light.

[0094] An optical fiber monofilament 201 is inserted into the aperture 311 so that the size of the light spot can be controlled through the aperture 311. The reaction cup 312 is used to place the sample to be detected. After the light beam passes through the sample to be detected, it passes through the second filter 315 to transmit the optical information to the first light receiver 313.

[0095] Further, in this embodiment, please refer to Figure 5 , Figure 7 , Figures 9 to 11 The detection module 300 includes Y×S first light receivers 313, 4 second light receivers 314 and corresponding optical components. The first light receivers 313 are arranged in the direction in which the light beam emitted by the optical fiber monofilament 201 passes through the reaction cup 312, and the first light receivers 313 are arranged in two rows. Each reaction cup 312 is arranged between the two rows of first light receivers 313. Each row has 1 / 2×Y×S first light receivers 313 integrated on the transmission photoelectric detection board, so as to collect transmission information.

[0096] At the four corners of the detection module 300, a second light receiver 314 is arranged in the vertical direction of the light beam emitted by the optical fiber filament 201 passing through the reaction cup 312, that is, there are four second light receivers 314, so as to receive the scattered signal of the light beam. Compared with the transmission methodology, the scattering method has higher sensitivity.

[0097] It can be understood that, taking coagulation sample detection as an example, the transmission methodology has the Lambert-Beer law as its theoretical basis, and the scattering methodology has the Rayleigh law as its theoretical basis. The transmission methodology has a simple optical path, and the scattering methodology has a higher sensitivity. Through the above-mentioned structural setting, the switching or multiplexing of the scattering transmission detection methodology can be realized, thereby enhancing the accuracy of the results and supporting functions such as multi-project and interference detection.

[0098] In this embodiment, the specific arrangement of the detection module 300 may have various implementations.

[0099] In one embodiment, see Figure 7The detection module 300 includes 28 first light receivers 313, 4 second light receivers 314 and corresponding optical components. Each row of 14 first light receivers 313 is integrated on the transmission photoelectric detection board to collect transmission information. Each detection module 300 can be adapted to two second light output ends 232. Through the detection module 300 of this embodiment, 28 or more channel detections can be achieved, which is conducive to improving batch detection efficiency.

[0100] In another embodiment, see Fig.11 , the detection module 300 has multiple ones, one of which is a detection module 300A, which includes 12 first light receivers 313, 4 second light receivers 314 and corresponding optical components, and each row has 6 first light receivers 313 integrated on the transmission photoelectric detection board, so as to collect transmission information. The 4 second light receivers 314 are distributed near the 4 corners of the detection module 300 to receive 90° scattered light. One of the detection modules 300B includes 14 first light receivers 313, 4 second light receivers 314 and corresponding optical components, and each row has 7 first light receivers 313 integrated on the transmission photoelectric detection board, so as to collect transmission information. The 4 second light receivers 314 are distributed near the 4 corners of the detection module 300 to receive 90° scattered light.

[0101] It can be seen from the above specific implementation that there are one or more detection modules 300. When there are multiple detection modules 300, the specific composition structures of each detection module 300 can be the same or different.

[0102] In summary, the optical measurement device in the sample analyzer of this embodiment can support multi-wavelength, multi-channel, high channel consistency, and multiplexing of scattering method and transmission method. It can be used in hospitals to improve batch detection efficiency, thereby alleviating the detection pressure of the hospital, and greatly improving the detection performance of the sample analyzer.

[0103] The present invention also provides a sample analysis method, which is applied to a sample analyzer. Figures 1 to 11 The sample analyzer includes a light source module 100, a detection module 300 and a light distribution module 200, the detection module 300 includes a plurality of detection components 310, the light distribution module 200 is arranged between the light source module 100 and the detection module 300, the light distribution module 200 includes a fiber combiner 210, a light homogenizer 220 and a fiber splitter 230, wherein the fiber combiner 210 includes a plurality of optical fiber filaments 201, and the sample analysis method includes the following steps:

[0104] S420 , providing a light beam to the light input end of the optical fiber combiner 210 through the light source module 100 .

[0105] S440, at the light output end of the fiber combiner 210, combine the optical fiber filaments 201 to form a first light output end 212, evenly distribute the optical fiber filaments 201 in the first light output end 212, receive the light beam emitted by the light source module 100 through the fiber combiner 210, and transmit the light beam to the light homogenizer 220.

[0106] S460 , the light beam is homogenized by the light homogenizer 220 , and the light beam is transmitted to the optical fiber beam splitter 230 .

[0107] S480 , evenly distribute the light beam to each detection component 310 through the optical fiber beam splitter 230 .

[0108] It can be understood that, at the light output end of the fiber combiner 210, the optical fiber filaments 201 are combined to form a first light output end 212, and the optical fiber filaments 201 in the first light output end 212 are evenly distributed, so that the light beam in each optical fiber filament 201 is uniform, so that the uniform light beam can be transmitted to the light homogenizer 220, thereby improving the uniformity of the light beam after being homogenized by the light homogenizer 220, so that a more uniform light beam can be transmitted to the fiber beam splitter 230, so that the light beam in each optical fiber filament 201 in the fiber beam splitter 230 is uniform, so as to reduce the difference between the optical channels and ensure the consistency of light intensity between the optical channels, thereby ensuring that the fiber beam splitter 230 can evenly distribute the light beam to the detection components 310 of the detection module 300, thereby increasing the accuracy of the sample analysis results, as well as the detection repeatability and stability of the sample analysis.

[0109] The above disclosure is only the preferred embodiment of the present invention, which certainly cannot be used to limit the scope of the present invention. Therefore, equivalent changes made according to the claims of the present invention are still within the scope of the present invention.

Claims

1. A light distribution module, characterized in that: The light distribution module includes a fiber combiner, a light homogenizer and a fiber beam splitter. The fiber combiner is used to receive a light beam emitted by a light source and transmit the light beam to the light homogenizer. The light homogenizer can homogenize the light beam and transmit the light beam to the fiber beam splitter. The fiber beam splitter can evenly distribute the light beam to each detection component of the detection module. The optical fiber combiner comprises a plurality of optical fiber filaments. At the light output end of the optical fiber combiner, the optical fiber filaments are combined to form a first light output end, and the optical fiber filaments are evenly distributed among the optical fiber filaments in the first light output end.

2. The light distribution module according to claim 1, characterized in that: The light output end of the optical fiber combiner is arranged opposite to the light input end of the light homogenizer, and the light output end of the optical fiber combiner and the light input end of the light homogenizer are arranged at intervals to form a first gap; and / or The light output end of the light homogenizer is arranged opposite to the light input end of the optical fiber beam splitter, and the light output end of the light homogenizer is arranged at an interval with the light input end of the optical fiber beam splitter to form a second gap.

3. The light distribution module according to claim 2, characterized in that: The first gap is no larger than 3 mm, and the second gap is no larger than 3 mm.

4. The light distribution module according to claim 1, characterized in that: At the light input end of the optical fiber combiner, the optical fiber single fibers are combined to form a first light input end; wherein the first light input end is combined to form one, and is used to be set corresponding to one of the light sources; or, the first light input end is combined to form a plurality of first light input ends, and is used to be set one by one corresponding to each of the light sources; The optical fiber splitter includes a plurality of optical fiber filaments, and at the light input end of the optical fiber splitter, the optical fiber filaments are bundled together to form a second light input end; wherein, the first light output end is bundled together to form one, and the light homogenizer and the second light input end are each provided with one; or, the first light output end is bundled together to form a plurality of optical fiber filaments, and the light homogenizer and the second light input end are each provided with a plurality of optical fiber filaments, and are provided one-to-one with each of the first light output ends.

5. An optical measuring device, characterized in that: The optical measuring device comprises a light source module, a detection module and a light distribution module as described in any one of claims 1 to 4, wherein the detection module comprises a plurality of detection components, the light source module is used to emit a light beam, and the light distribution module is arranged between the light source module and the detection module and is used to evenly distribute the light beam to each of the detection components.

6. The optical measuring device according to claim 5, characterized in that The light source module includes a plurality of main light sources, and the light emission wavelengths of the main light sources are different; The light source module further includes a secondary light source, the light emission wavelength of the secondary light source is the same as the light emission wavelength of one of the primary light sources, so as to be able to intensify the light emitted by one of the primary light sources.

7. The optical measuring device according to claim 6, characterized in that There are a plurality of auxiliary light sources, and they are arranged one-to-one correspondingly to a plurality of main light sources, so that each auxiliary light source can intensify the light emitted by each main light source.

8. The optical measuring device according to claim 5, characterized in that The detection assembly includes an aperture, a reaction cup, a first light receiver and a second light receiver. The light-emitting end of an optical fiber monofilament in the light distribution module, the aperture, the reaction cup and the first light receiver are spaced apart along a first direction. The second light receiver is arranged on the side of the reaction cup and avoids the straight line where the first direction is located. Wherein, the first light receiver is a transmission photoelectric converter, and the second light receiver is a scattering photoelectric converter.

9. A sample analyzer, characterized in that: The sample analyzer comprises the light distribution module according to any one of claims 1 to 4, or the optical measurement device according to any one of claims 5 to 8.

10. A sample analysis method, characterized in that: The sample analysis method is applied to a sample analyzer, which includes a light source module, a detection module and a light distribution module, wherein the detection module includes a plurality of detection components, the light distribution module is arranged between the light source module and the detection module, and the light distribution module includes a fiber combiner, a light homogenizer and a fiber beam splitter, wherein the fiber combiner includes a plurality of optical fiber filaments, and the sample analysis method includes the following steps: Providing a light beam to the light input end of the optical fiber combiner through the light source module; At the light output end of the optical fiber combiner, the optical fiber single fibers are combined to form a first light output end, and the optical fiber single fibers in the first light output end are evenly distributed, and the light beam emitted by the light source module is received by the optical fiber combiner, and the light beam is transmitted to the light homogenizer; The light beam is homogenized by the light homogenizer, and the light beam is transmitted to the optical fiber beam splitter; The optical fiber beam splitter is used to evenly distribute the light beam to each of the detection components.

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