A drug balloon dilation catheter and methods of using the same

Abstract

The present application relates to a kind of medicine balloon dilatation catheter and its using method, which includes inner tube, outer tube, balloon, medicine patch and support mechanism, support mechanism includes support and push-pull piece with initial state and support state, support has multiple support parts corresponding with medicine patch and located in balloon on support, when support is in initial state, support part is straight and not in contact with balloon;When support is in support state, support part is arched outward and can push up corresponding medicine patch outward. By making support part on support mechanism arch outward and push up medicine patch, on the one hand, medicine patch can be pre-applied to the wall of diseased blood vessel, so as to realize the pre-release of medicine, and relieve inflammation caused by vessel expansion;On the other hand, part of the balloon wall is anchored on the vessel wall, preventing the displacement of the balloon during expansion, and the stability is better.

Description

TECHNICAL FIELD

[0001] The present application belongs to the technical field of medical devices, and particularly relates to a drug balloon dilatation catheter and a use method thereof. BACKGROUND

[0002] Drug balloon dilatation is a new technology that uses a balloon to fully dilate a diseased blood vessel, directly contacts the balloon with the diseased blood vessel, and releases drugs. A common drug balloon dilatation catheter includes a balloon, an inner tube, an outer tube, and a tube seat. The surface of the balloon is provided with a drug coating. A medium is filled into the balloon through a pressure port on the tube seat to pressurize the balloon and make the balloon expand. After the balloon expands, it can extrude the plaque of the stenosis of the blood vessel and adhere to the inner wall of the blood vessel. The drugs on the balloon can be released to act on the diseased blood vessel, so as to inhibit the proliferation of the intima of the blood vessel wall and reduce the occurrence of the disease.

[0003] However, the existing drug balloon dilatation catheter may have a risk of sliding during operation, especially in complex blood vessel morphology or high blood flow velocity area. In addition, the existing drug balloon dilatation catheter needs to make the balloon dilate and contact the diseased blood vessel, and then the drugs on the surface of the balloon can act on the diseased blood vessel. For the damaged blood vessel, it is easy to cause inflammation of the blood vessel. SUMMARY

[0004] The purpose of the present application is to provide a new drug balloon dilatation catheter and a use method thereof.

[0005] To achieve the above-mentioned purpose, the technical solution adopted by the present application is as follows:

[0006] A drug balloon dilatation catheter includes an inner tube, an outer tube, and a balloon. A part of the inner tube is arranged in the inside of the balloon. The outer tube is arranged outside the inner tube and forms a cavity between the inner tube and the outer tube. The cavity can be used to transmit a filling medium into the balloon to drive the balloon to expand or contract. The drug balloon dilatation catheter further includes:

[0007] A drug patch is arranged outside the balloon. The drug patch has a plurality of drug patches arranged outside the balloon.

[0008] A supporting mechanism includes a supporting piece having an initial state and a supporting state, and a push-pull piece movably arranged in the cavity. The supporting piece has a plurality of supporting portions arranged corresponding to the drug patches and located in the balloon. When the supporting piece is in the initial state, the supporting portions are straightened and do not contact the balloon. When the supporting piece is in the supporting state, the supporting portions are arched outward and can push the corresponding drug patches outward. One end of the supporting piece is connected to the inner tube, and the other end is connected to the push-pull piece. The supporting piece can be switched between the supporting state and the initial state under the control of the push-pull piece.

[0009] The present application can anchor part of the balloon wall on the blood vessel wall, increase the connection stability of the balloon and the blood vessel wall, and prevent the displacement of the balloon during the expansion process.

[0010] Preferably, the support member further comprises a plurality of support rings arranged along the axial direction of the inner tube, the support rings are sleeved on the outer side of the inner tube, the most distal support ring is fixedly connected to the inner tube, the most proximal support ring is connected to the push-pull member, and the support rings other than the most distal support ring are slidable relative to the inner tube, and one or more support portions are connected between adjacent two support rings.

[0011] In some embodiments, the support portion comprises a first support arm and a second support arm connected in rotation, and the distal ends of the first support arm and the second support arm away from each other are connected to the corresponding adjacent two support rings, respectively.

[0012] In some embodiments, when a plurality of support portions are arranged between the adjacent two support rings, the plurality of support portions between the adjacent two support rings are arranged around the axial line of the inner tube.

[0013] In some embodiments, the number of support portions between different adjacent two support rings is the same or different.

[0014] In some embodiments, the support portion and the support portion adjacent thereto and located at the proximal end and / or the distal end are staggered.

[0015] Preferably, when the support member is in the supporting state, the support portion arches outwardly in a triangular shape.

[0016] Preferably, the support member is integrally formed.

[0017] In some embodiments, the support member is integrally formed by laser engraving technology.

[0018] Preferably, the support member is made of stainless steel.

[0019] Preferably, the drug patch comprises a first patch connected to the balloon on the circumferential side and a second patch loaded with drugs between the first patch and the balloon, and a plurality of micropores for releasing the drugs are formed on the first patch.

[0020] Further preferably, the first patch completely covers the second patch and leaves a certain edge around.

[0021] In some embodiments, the first patch and the second patch are circular.

[0022] In some embodiments, the first patch is made of polyethylene or polylactic acid.

[0023] In some embodiments, the second patch is made of sodium alginate or polyvinyl alcohol.

[0024] In some embodiments, the drug is selected from one or more of an anti-proliferative drug (including but not limited to paclitaxel), an anti-thrombotic drug (including but not limited to sirolimus).

[0025] Further, the drug is sirolimus. Sirolimus is relatively stable at room temperature and has good sustained release effect, which can continuously inhibit the proliferation of vascular smooth muscle cells and reduce the occurrence of restenosis.

[0026] Preferably, the preparation method of the drug patch comprises the following steps:

[0027] S1, uniformly distributing the drug on the surface of the second patch by dipping or spraying process;

[0028] S2, covering the first patch on the outside of the second patch, and using a local hot melting tool or a hot melting head to heat the periphery of the first patch (the area outside the second patch) to make the first patch melt with the balloon surface;

[0029] S3, heat-shrinking the drug patch, including using a low-temperature hair dryer to uniformly blow the first patch to make it shrink and tightly adhere to the balloon surface. At the same time, the first patch shrinks to fix the internal drug patch on the balloon surface. The temperature of the hot air should be controlled within the range that does not affect the stability of the drug (usually not more than 50-60℃).

[0030] Further preferably, the preparation method of the drug patch further comprises micropore processing of the first patch. The micropore processing can be performed by laser drilling or other micropore forming operations.

[0031] In some embodiments, the micropore processing is performed before the first patch covers the second patch.

[0032] In some embodiments, the micropore processing is performed after the heat-shrinking fixation.

[0033] Preferably, the drug balloon dilatation catheter further comprises a driving mechanism, the driving mechanism comprising a handle connected to the outer tube and / or the inner tube, and a transmission member and a driving assembly arranged on the handle, the transmission member being connected between the push-pull member and the driving assembly and being controlled by the driving assembly, the transmission member being capable of moving with the push-pull member to switch the support member between the support state and the initial state.

[0034] The application also provides a method for using the drug balloon dilatation catheter as described above, which comprises the following steps:

[0035] (1) placing the balloon at a vascular lesion site;

[0036] (2) controlling the movement of the push-pull member to switch the support member from the initial state to the support state, and keeping the support member in the support state to perform the pre-release of the drug;

[0037] (3) introducing a filling medium into the balloon through the lumen to make the balloon expand outward and perform expansion keeping;

[0038] (4) controlling the movement of the push-pull member to switch the support member from the support state to the initial state, discharging the filling medium in the balloon through the lumen to make the balloon contract, and withdrawing the balloon.

[0039] Preferably, the height at which the balloon wall in the expanded state is controlled to be located is not lower than the height at which the support portion is located.

[0040] Thanks to the above technical solution, the application has the following advantages compared with the prior art:

[0041] The drug balloon dilatation catheter of the application comprises an inner tube, an outer tube, a balloon, a drug patch and a support mechanism, wherein the support portion on the support mechanism can arch outward and lift the drug patch, which on one hand anchors part of the balloon wall on the vascular wall to prevent the displacement of the balloon during the expansion process and has better stability, and on the other hand can pre-adhere the drug patch to the lesion vascular wall to realize the pre-release of the drug and relieve the inflammation caused by the vascular expansion. BRIEF DESCRIPTION OF DRAWINGS

[0042] In order to more clearly illustrate the technical solutions of the embodiments of the application, the drawings needed in the embodiment description will be briefly introduced. Obviously, the drawings in the following description are only some embodiments of the application, and other drawings can be obtained by those skilled in the art without creative effort.

[0043] Figure 1 FIG. 1 is a structural schematic diagram of the drug balloon dilatation catheter of Example 1;

[0044] Figure 2 FIG. 2 is a structural schematic diagram of the distal end portion of the drug balloon dilatation catheter of Example 1;

[0045] Figure 3 FIG. 3 is a perspective view of the distal end portion of the drug balloon dilatation catheter of Example 1;

[0046] Figure 4 Cross-sectional view of the distal end of the drug balloon dilatation catheter of Example 1, wherein the support is in the initial state;

[0047] Figure 5 Cross-sectional view of the distal end of the drug balloon dilatation catheter of Example 1, wherein the support is in the supporting state and the balloon is in the contracted state;

[0048] Figure 6 Cross-sectional view of the distal end of the drug balloon dilatation catheter of Example 1, wherein the support is in the supporting state and the balloon is in the expanded state;

[0049] Figure 7 Structural schematic view of the support in the initial state of Example 1;

[0050] Figure 8 Structural schematic view of the support in the supporting state of Example 1;

[0051] Figure 9 Structural schematic view of the support and the support ring of Example 1;

[0052] Figure 10 Schematic view of the half-section structure of the drug patch of Example 1;

[0053] Figure 11 Cross-sectional view of the driving mechanism of Example 1;

[0054] Figure 12 Physical model view of the distal end of the drug balloon dilatation catheter of Example 1;

[0055] 1. balloon;

[0056] 2. drug patch; 21. first patch; 211. adhesive area; 212. permeation area; 22. second patch;

[0057] 3. support mechanism; 31. support; 311. support ring; 312. support part; 3121. first support arm; 3122. second support arm;

[0058] 4. inner tube;

[0059] 5. outer tube;

[0060] 6. driving mechanism; 61. handle; 62. transmission tube; 63. cam; 64. transmission rod; 65. operating part; 66. first rotating wheel; 67. second rotating wheel;

[0061] 7. guide wire. DETAILED DESCRIPTION

[0062] In the following description, certain example embodiments will simply be described. As can be appreciated by those skilled in the art, the disclosed embodiments can be modified in various different ways without departing from the spirit or scope of embodiments of the present application. Therefore, the drawings and description are to be regarded as illustrative in nature and not restrictive.

[0063] In the description of embodiments of the present application, it needs to be understood that the terms "far", "near" and the like indicate the position or location relationship defined in the position of the drug balloon dilatation catheter in use, wherein the side close to the operator is the proximal end and the side away from the operator is the distal end. Only for the purpose of facilitating the description of embodiments of the present application and simplifying the description, it is not intended to indicate or imply that the indicated device or element must have a particular position, be constructed and operated in a particular position, and therefore cannot be understood as a limitation of embodiments of the present application.

[0064] In addition, the terms "first", "second" are only for the purpose of description, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first", "second" can explicitly or implicitly include one or more of the features. In the description of embodiments of the present application, the meaning of "multiple" is two or more, unless otherwise specifically limited.

[0065] In embodiments of the present application, unless otherwise specifically defined and limited, "on" or "under" of a first feature to a second feature can include that the first and second features are in direct contact, or that the first and second features are not in direct contact but are in contact through another feature between them. Moreover, "on", "above" and "over" of the first feature to the second feature includes that the first feature is directly above and obliquely above the second feature, or only indicates that the first feature is higher in horizontal height than the second feature. "Below", "under" and "underneath" of the first feature to the second feature includes that the first feature is directly below and obliquely below the second feature, or only indicates that the first feature is lower in horizontal height than the second feature.

[0066] The following disclosure provides many different embodiments or examples for implementing different structures of embodiments of the present application. In order to simplify the disclosure of embodiments of the present application, the components and arrangements of specific examples are described in the following. Of course, they are only examples and the purpose is not to limit the present application. In addition, reference numerals and / or reference letters can be repeated in different examples of the present application, and such repetition is for the purpose of simplification and clarity, and does not itself indicate a relationship between the various embodiments and / or arrangements discussed.

[0067] The existing drug balloon dilatation catheter is usually expanded outward by balloon inflation to dilate the narrow blood vessel, and the drug on the balloon acts on the inner wall of the blood vessel. Such dilatation catheter has the following problems: first, due to the influence of blood flow, the balloon is easy to slide during the process of dilating the blood vessel, so it is difficult to accurately act on the target lesion position; second, it is difficult to realize local pressurization and drug release, which can easily lead to poor treatment effect and increased risk of blood vessel restenosis. In view of the above problems, the present application provides a drug balloon dilatation catheter, which can make the drug patch on the balloon be lifted to the specified position of releasing drug according to the demand by setting a supporting mechanism, avoid the sliding of the balloon due to the influence of blood flow, and realize the positioning of the drug patch. In addition, the drug patch is pre-released in the narrow blood vessel to treat the blood vessel wall, which can relieve the inflammation caused by the blood vessel expansion. The embodiments of the present application will be described in detail below with reference to the accompanying drawings.

[0068] Embodiment 1

[0069] A drug balloon dilatation catheter, as shown in Figures 1 to 12 , which comprises a balloon 1, an inner tube 4, an outer tube 5, a drug patch 2 and a supporting mechanism 3.

[0070] The balloon 1 can be radially expanded or contracted, and its specific structure can refer to the prior art, which is not particularly limited in the present application.

[0071] A part of the inner tube 4 is arranged in the inside of the balloon 1, specifically, the distal end of the inner tube 4 is inserted into the balloon 1 and fixedly connected with the distal end of the balloon 1. The outer tube 5 is arranged outside the inner tube 4, and its distal end is inserted into the balloon 1 and fixedly connected with the proximal end of the balloon 1. The cavity is formed between the outer tube 5 and the inner tube 4, which can be used to transmit the filling medium into the balloon 1 to drive the balloon 1 to expand or contract. The filling medium refers to the prior art, for example, it can be normal saline, contrast agent, etc.

[0072] The supporting mechanism 3 comprises a supporting piece 31 having an initial state and a supporting state, and a push-pull piece movably arranged in the cavity. As an example, the push-pull piece can be a pipe arranged outside the outer tube and in contact or connected with the proximal end of the supporting piece 31, and the push-pull piece can be controlled to slide along the axial direction of the inner tube 4.

[0073] Referring to Figure 9As shown, the support member 31 comprises a plurality of support rings 311 and support portions 312. The plurality of support rings 311 are sleeved on the inner tube 4 and arranged in sequence along the axial direction of the inner tube 4. The most distal support ring 311 is fixedly connected to the inner tube 4. The support rings 311 other than the most distal support ring 311 can slide relative to the inner tube 4. One or more support portions 312 are connected between two adjacent support rings 311. When a plurality of support portions 312 are arranged between two adjacent support rings 311, the plurality of support portions 312 are uniformly arranged around the axis of the inner tube 4. Preferably, 2-4 support portions 312 are connected between two adjacent support rings 311. The number of support portions 312 between different adjacent support rings 311 is the same or different. In this embodiment, the number of support portions 312 between different adjacent support rings 311 is the same, and the support portions 312 between the same adjacent support rings 311 and the support portions 312 adjacent thereto and located at the proximal end and / or the distal end are arranged alternately. Generally, the support portions 312 are located in the balloon 1. In the initial state, the support portions 312 are straight and do not contact the balloon 1. When the support member 31 is switched from the initial state to the support state, the support rings 311 other than the most distal support ring 311 slide relative to the inner tube 4 towards the distal end, causing the support portions 312 to arch outward, thereby pushing the balloon 1 wall in contact therewith outward to anchor the balloon 1 wall in the stenosis region and prevent the balloon 1 from sliding.

[0074] Preferably, the support portions 312 arch outward in a triangular shape. Specifically, the support portions 312 comprise first support arms 3121 and second support arms 3122 connected in rotation. The ends of the first support arms 3121 and the second support arms 3122 away from each other are connected to the corresponding adjacent support rings 311, respectively. When the support rings 311 slide relative to the inner tube 4 towards the distal end, the support rings 311 press the support portions 312, causing the connection of the first support arms 3121 and the second support arms 3122 to move in a direction away from the axis of the inner tube 4, i.e. arch outward, thereby pushing part of the balloon 1 wall to a predetermined position; when the support rings 311 slide in the opposite direction, the support rings 311 pull the support portions 312 to straighten them.

[0075] The support member 31 is preferably integrally formed, for example, by laser engraving technology. Preferably, the support member 31 is made of a pipe made of stainless steel material.

[0076] The most proximal support ring 311 of the support member 31 is connected to the push-pull member. Under the driving of the push-pull member, the support member 31 can be switched between the initial state and the support state.

[0077] Referring to Figures 1 to 3The drug patches 2 are arranged outside the balloon 1, preferably corresponding to the support portions 312, and are located at the outer region of the balloon 1 wall contacted by the support portions 312 in the supporting state, so as to be pushed outward by the support portions 312 when the support portions 312 arch outward.

[0078] Further, referring to Figure 10 The drug patches 2 include a first patch 21 and a second patch 22. The first patch 21 includes a permeation region 212 in the middle and an adhesive region 211 around the permeation region 212, the permeation region 212 is provided with a plurality of micropores for releasing drugs, and the adhesive region 211 is adhered to the balloon 1 by a hot melt process or glue. As preferred, the first patch 21 is made of polyethylene (PE) or polylactic acid (PLA), which has good biocompatibility and can realize heat shrinkage and hot melting at a relatively low temperature. The second patch 22 is located between the first patch 21 and the balloon 1 and carries drugs, which is preferably a material with good drug adsorption capacity and biocompatibility, such as sodium alginate, polyvinyl alcohol (PVA) or other biodegradable polymers. The drugs include but are not limited to anti-proliferative drugs (such as paclitaxel) or anti-thrombotic drugs (such as sirolimus).

[0079] Referring to Figure 1 and Figure 11 The drug balloon dilatation catheter further includes a driving mechanism 6, the driving mechanism 6 includes a handle 61 connected to the outer tube 5 and / or the inner tube 4, and a transmission member and a driving assembly arranged on the handle 61, the transmission member is connected between the push-pull member and the driving assembly and is controlled by the driving assembly, and the transmission member can move the push-pull member axially along the inner tube 4 to switch the support member 31 between the supporting state and the initial state.

[0080] In this embodiment, the proximal ends of the inner tube 4 and the outer tube 5 are connected to the handle 61, and the proximal end of the inner tube 4 extends out of the outer tube 5. The handle 61 has a pressurized cavity connected to the lumen and used for introducing the filling medium, and a guide wire cavity connected to the inner tube 4 and used for introducing the guide wire 7. The transmission member includes a transmission tube 62 screwed to the handle 61 and located between the inner tube 4 and the outer tube 5, a cam 63 connected to the transmission tube 62, and a transmission rod 64 fixedly connected to the cam 63. When the transmission rod 64 is rotated, the cam 63 on it is rotated and drives the transmission tube 62 to spiral along the axial direction of the inner tube 4, thereby driving the push-pull rod to move axially along the inner tube 4. The drive assembly includes an operating part 65, a first rotating wheel 66, and a second rotating wheel 67, wherein the second rotating wheel 67 is fixedly connected to the proximal end of the transmission rod 64; the first rotating wheel 66 is engaged between the operating part 65 and the second rotating wheel 67, and has a plurality of distributed on the outer periphery of the second rotating wheel 67. Rotating the operating part 65, the first rotating wheel 66 rotates with the second rotating wheel 67 under the drive of the operating part 65, and the second rotating wheel 67 rotates with the transmission rod 64, thereby causing the cam 63 on the transmission rod 64 to spiral along the axial direction of the inner tube 4 with the transmission tube 62. Of course, the drive mechanism 6 can also be other structures in the prior art.

[0081] Working principle:

[0082] (1) Place the balloon 1 at the vascular lesion site;

[0083] (2) Control the push-pull member to move to switch the support member 31 from the initial state to the support state, and keep the support member 31 in the support state, which specifically includes rotating the operating part 65, the operating part 65 drives the first rotating wheel 66 to rotate with the second rotating wheel 67, and the second rotating wheel 67 rotates synchronously with the transmission rod 64 and the cam 63, thereby driving the first transmission tube 62 to spiral towards the distal end, and further driving the push-pull rod to move axially along the inner tube 4 towards the distal end, causing the support portion 312 to arch outward and lift the drug patch 2, so that the drug patch 2 acts on the stenosis region, and the pre-release of the drug is realized;

[0084] (3) Introduce the filling medium into the balloon 1 through the lumen to make the balloon expand outward and maintain the expansion, which specifically includes introducing the filling medium into the balloon 1 through the pressurized cavity to make the balloon 1 expand until the height of the balloon wall in the expanded state is greater than the height of the support portion 312, i.e. the balloon wall is located outside the support portion 312;

[0085] (4) Control the push-pull member to move to switch the support member 31 from the support state to the initial state, which specifically includes reversing the rotation of the operating part 65 to switch the support member 31 from the support state to the initial state, and discharging the filling medium in the balloon through the filling port to make the balloon contract, and then withdrawing the balloon.

[0086] The above examples are only for illustrating the technical concept and characteristics of the present application, and the purpose is to enable those skilled in the art to understand the content of the present application and to implement it, and cannot limit the protection scope of the present application. Any equivalent changes or modifications made according to the spirit and essence of the present application shall be covered within the protection scope of the present application.

Claims

1. A drug balloon dilatation catheter, comprising an inner tube (4), an outer tube (5) and a balloon (1), a part of the inner tube (4) is arranged in the interior of the balloon (1), the outer tube (5) is arranged outside the inner tube (4) and a cavity is formed between the inner tube (4) and the outer tube (5), the cavity can be used to transmit filling medium into the balloon (1) to drive the balloon (1) to expand or contract, characterized in that, The drug balloon dilatation catheter further comprises: a drug patch (2) arranged outside the balloon (1); a supporting mechanism (3) comprising a supporting member (31) having an initial state and a supporting state, and a push-pull member movably arranged in the lumen, the supporting member (31) having a plurality of supporting portions (312) arranged corresponding to the drug patch (2) and located in the balloon (1), and a plurality of supporting rings (311) arranged along the axial direction of the inner tube (4) and sleeved outside the inner tube (4), the most distal supporting ring (311) being fixedly connected to the inner tube (4), the most proximal supporting ring (311) being connected to the push-pull member, the other supporting rings (311) being slidable relative to the inner tube (4), and one or more supporting portions (312) being connected between any two adjacent supporting rings (311); when the supporting member (31) is in the initial state, the supporting portions (312) are straight and do not contact the balloon (1); when the supporting member (31) is in the supporting state, the supporting portions (312) arch outward and can push the corresponding drug patch (2) outward, one end of the supporting member (31) being connected to the inner tube (4) and the other end being connected to the push-pull member, the supporting member (31) being switchable between the supporting state and the initial state under the control of the push-pull member.

2. The drug balloon dilation catheter of claim 1, wherein, The supporting portion (312) comprises a first supporting arm (3121) and a second supporting arm (3122) connected rotatably, and the distal ends of the first supporting arm (3121) and the second supporting arm (3122) are connected to the corresponding adjacent two supporting rings (311), respectively; and / or, when a plurality of supporting portions (312) are arranged between the adjacent two supporting rings (311), the plurality of supporting portions (312) are arranged around the axis of the inner tube (4); and / or, the number of supporting portions (312) between different adjacent two supporting rings (311) is the same or different; and / or, the supporting portions (312) and the supporting portions (312) adjacent to them and located at the proximal end and / or the distal end are arranged alternately.

3. The drug balloon dilation catheter of claim 1, wherein, When the supporting member (31) is in the supporting state, the supporting portions (312) arch outward in a triangular shape.

4. The drug balloon dilation catheter of claim 1, wherein, The supporting member (31) is integrally formed; and / or, the supporting member (31) is made of stainless steel.

5. The drug balloon dilation catheter of claim 1, wherein, The drug patch (2) comprises a first patch (21) connected to the balloon (1) on the peripheral side, and a second patch (22) located between the first patch (21) and the balloon (1) and loaded with drugs, and a plurality of micropores are formed in the first patch (21) for releasing the drugs.

6. The drug balloon dilation catheter of claim 5, wherein, The first patch (21) is made of polyethylene or polylactic acid; and / or, the second patch (22) is made of sodium alginate or polyvinyl alcohol; and / or, The drug is selected from one or more of an antiproliferative drug, an antithrombotic drug.

7. The drug balloon dilation catheter of claim 1, wherein, The drug balloon dilatation catheter further comprises a driving mechanism (6) comprising a handle (61) connected to the outer tube (5) and / or inner tube (4) and a transmission member and a driving assembly arranged on the handle (61), the transmission member being connected between the push-pull member and the driving assembly and being controlled by the driving assembly, the transmission member being capable of moving with the push-pull member to switch the support member (31) between the support state and the initial state.

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