Esophageal squamous cell carcinoma rapid detection system based on near infrared spectrum technology and water spectrum omics and working method of esophageal squamous cell carcinoma rapid detection system

CN119322034APending Publication Date: 2025-01-17SHANDONG UNIV
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Patent Information

Application Number
CN202411416984.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-10-11
Publication Date
2025-01-17

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Abstract

The invention relates to an esophageal squamous cell carcinoma rapid detection system based on a near infrared spectrum technology and water spectrum omics and a working method thereof, and the system comprises a spectrum collection unit which is used for collecting a near infrared spectrum of a to-be-detected plasma sample and obtaining spectrum data; the spectrum preprocessing unit is used for preprocessing the near infrared spectrum of the to-be-detected plasma sample and eliminating the influence of instrument noise and environmental change on the spectrum; the spectral data analysis unit is used for carrying out waveband selection, principal component analysis and partial least square discriminant analysis on the near infrared spectral data and identifying a wavelength with a high contribution degree; and the water spectrum omics unit is used for selecting 12 characteristic wavelengths by combining spectral data analysis and a water spectrum omics principle, establishing a water absorption spectrum mode pattern for spectral data at the characteristic wavelengths, and carrying out rapid detection by characterizing a water species structure change rule in the plasma of the esophageal squamous carcinoma patient. The method has good practical application and reference value for large-scale screening of cancers.
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