Mild hand sanitizer with efficient antibacterial effect and application of mild hand sanitizer

Abstract

The invention discloses a mild hand sanitizer with an efficient antibacterial effect and application of the mild hand sanitizer. The mild hand sanitizer is prepared from the following components: water, a surfactant, a humectant, lactic acid, a chelating agent and a preservative. The mild hand sanitizer composition with the efficient antibacterial effect has the beneficial effects that the pH value of a system is reduced through lactic acid, so that bacteria are under the condition that the pH value is 4-5 and the bacteria are not easy to grow, but the hand is mild and free of irritation, and meanwhile, the growth of the bacteria can be inhibited, so that the purposes of cleaning hand skin, keeping the skin clean and moist, and keeping the skin clean and moist are achieved. The side effect is small, and the safety is high.

Description

Technical Field

[0001] The invention relates to the technical field of hand washing liquid, in particular to a mild hand washing liquid with high-efficiency antibacterial effect and application thereof. Background Art

[0002] Hand sanitizer is a skin care cleansing liquid used to clean hands. It exerts the cleaning effect of surfactants through friction, and can remove dirt and attached bacteria on hands with or without water. When using, first wet your hands with clean water, take an appropriate amount of hand sanitizer on the palm of your hand and rub your hands thoroughly for at least 30 seconds. During this process, pay attention to rubbing the fingertips and finger gaps, and allow the foam to cover all parts of the hand. After rubbing, rinse with running water. Finally, be sure to dry with a clean dry towel or paper towel.

[0003] Most diseases enter the body through the mouth. Many pathogens are transported from the hands to the mouth, or enter the body through contact between the hands and the nose, eyes and other parts of the body. Hands are one of the main channels for introducing pathogens, so washing hands has become an effective way to prevent diseases. Most of the existing hand sanitizers cannot quickly inhibit bacteria, are relatively irritating to the skin, and have many side effects. For this reason, mild hand sanitizers with fast and efficient antibacterial effects are designed. Summary of the invention

[0004] The purpose of the present invention is to solve the above problems and to design a mild hand washing liquid with high-efficiency antibacterial effect and its application.

[0005] The technical solution of the present invention to achieve the above-mentioned purpose is a mild hand sanitizer with high-efficiency antibacterial effect, comprising the following components: water, surfactant, moisturizer, lactic acid, chelating agent, and preservative.

[0006] As a further description of the technical solution, the components are as follows in terms of mass percentage: water balance, surfactant 7-10%, moisturizer 0.5-3%, lactic acid 0.2-4%, chelating agent 0.05-2%, and preservative 0.05-1%.

[0007] As a further description of the technical solution, the surfactant is a mixture of one or more of AES (sodium laureth sulfate), CAB (cocamidopropyl betaine), and CMEA (cocoamide MEA).

[0008] As a further description of the technical solution, the source of the AES (sodium laureth sulfate) is obtained by synthesis, the source of the CAB (cocamidopropyl betaine) is obtained by synthesis, and the source of the CMEA (cocoamide MEA) is obtained by synthesis.

[0009] As a further description of the technical solution, the moisturizing agent is a mixture of one or more of glycerol, propylene glycol, and butylene glycol.

[0010] As a further description of the technical solution, the source of the glycerol is obtained from saponification by-products, the source of the propylene glycol is obtained through synthesis, and the source of the butylene glycol is obtained through synthesis.

[0011] As a further description of the technical solution, the source of the lactic acid is obtained by fermentation.

[0012] As a further description of the technical solution, the chelating agent is a mixture of one or more of EDTA-2Na, sodium citrate, and sodium gluconate, and the preservative is a mixture of one or more of kasone, DMDM ​​H (DMDM hydantoin), sodium benzoate, and phenoxyethanol.

[0013] As a further description of the technical solution, the source of the EDTA-2Na is obtained by synthesis, the source of the sodium citrate is obtained by synthesis, and the source of the sodium gluconate is obtained by synthesis.

[0014] Mild hand sanitizer with high antibacterial effect for use in cosmetics and personal care products.

[0015] The beneficial effect is that the mild hand sanitizer combination with high-efficiency antibacterial effect of the present invention reduces the pH value of the system through lactic acid, so that bacteria are placed under a pH condition of 4-5 where it is not easy to grow, but is gentle to the hands and does not cause irritation. At the same time, it can inhibit the growth of bacteria, thereby achieving the purpose of cleaning the hand skin, keeping the skin clean and moisturized, with small side effects and high safety. DETAILED DESCRIPTION

[0016] First of all, the original intention of the design of the present invention is explained. Most diseases are transmitted through the mouth. Many pathogens are transported into the mouth through the hands, or enter the body through the contact between the hands and the nose, eyes and other parts. Hands are one of the main channels for bringing in pathogens, so washing hands has become an effective way to prevent diseases. Most of the existing hand sanitizers cannot quickly inhibit bacteria, and are more irritating to the skin and have more side effects. Therefore, the present invention designs a mild hand sanitizer with high-efficiency antibacterial effect and its application.

[0017] The present invention will be described in detail below. A mild hand soap with high-efficiency antibacterial effect comprises the following components: water, a surfactant, a moisturizer, lactic acid, a chelating agent, and a preservative.

[0018] The components are as follows according to mass percentage: water balance, surfactant 7-10%, moisturizer 0.5-3%, lactic acid 0.2-4%, chelating agent 0.05-2%, and preservative 0.05-1%.

[0019] Wherein, the surfactant is a mixture of one or more of AES (sodium laureth sulfate), CAB (cocamidopropyl betaine), and CMEA (cocamide MEA); the source of AES (sodium laureth sulfate) is synthetic, the source of CAB (cocamidopropyl betaine) is synthetic, and the source of CMEA (cocamide MEA) is synthetic.

[0020] The moisturizing agent is a mixture of one or more of glycerol, propylene glycol and butylene glycol.

[0021] The glycerol is obtained from saponification byproducts, the propylene glycol is obtained from synthesis, and the butylene glycol is obtained from synthesis.

[0022] The lactic acid is obtained from fermentation.

[0023] The chelating agent is a mixture of one or more of EDTA-2Na, sodium citrate, and sodium gluconate; the preservative is a mixture of one or more of kasone, DMDM ​​H (DMDM hydantoin), sodium benzoate, and phenoxyethanol; the EDTA-2Na is synthesized, the sodium citrate is synthesized, and the sodium gluconate is synthesized.

[0024] Mild hand sanitizer with high antibacterial effect for use in cosmetics and personal care products.

[0025] In a preferred embodiment of the present invention, the mild hand sanitizer combination with high-efficiency antibacterial effect includes water, AES, CAB, CMEA, glycerol, propylene glycol, butylene glycol, lactic acid, EDTA-2Na, sodium citrate, sodium gluconate, kason, DMDM ​​H, sodium benzoate, phenoxyethanol, etc. The content of each component is as follows: by mass percentage, water balance, AES 5-8%, CAB 1.5-3%, CMEA 0.1-1.5%, glycerol 0.1-2%, propylene glycol 0.1-1%, butylene glycol 0.1-0.5%, lactic acid 0.2-4%, EDTA-2Na 0.02-0.15%, sodium citrate 0.02-1%, sodium gluconate 0.01-1%, kason 0.0001-0.001%, DMDM ​​H 0.01-0.4%, sodium benzoate 0.01-0.4%, phenoxyethanol 0.01-0.8%.

[0026] The present invention will be described in detail below with reference to the embodiments:

[0027] Embodiment 1:

[0028] Provided is a mild hand sanitizer combination with high-efficiency antibacterial effect, which consists of water, a surfactant, a moisturizer, lactic acid, a chelating agent, a preservative, etc. The content of each component is as follows: by mass percentage, water balance, AES 5.5%, CAB 2.5%, CMEA 1.5%, glycerol 2%, propylene glycol 0.7%, butylene glycol 0.1%, lactic acid 0.5%, EDTA-2Na 0.05%, sodium citrate 0.7%, sodium gluconate 0.6%, kason 0.001%, DMDM ​​H 0.01%, sodium benzoate 0.2%, and phenoxyethanol 0.4%.

[0029] The production process of the mild hand sanitizer with high efficiency and antibacterial effect comprises the following steps:

[0030] (1) At room temperature and pressure, AES, CAB, CMEA, glycerol, propylene glycol, and butylene glycol are added to water in sequence, stirred to dissolve completely, and then lactic acid, EDTA-2Na, sodium citrate, sodium gluconate, kasone, sodium benzoate, DMDM ​​H, and phenoxyethanol are added and stirred evenly;

[0031] (2) After filling, packaging and finished product testing, they can be put into storage or directly used for subsequent experiments.

[0032] Effect experiment: antibacterial test and skin irritation test (HRIPT)

[0033] Antibacterial test experiment: According to item 7.6 of QB / T 2738-2012, the antibacterial effect was tested and the accelerated stability antibacterial rate was tested in item 8. The system pH was 4.67 (10% aqueous solution, 25°C). Among them, the antibacterial rate test conditions were to directly use the stock solution, the action time was 1 minute, and the antibacterial rate against Staphylococcus aureus (ATCC 6538 or ATCC 27217) and Escherichia coli (8099 or ATCC 25922) was detected; the accelerated stability antibacterial rate test conditions were to place it at 37-40°C and >75% humidity for 3 months, directly use the stock solution, the action time was 1 minute, and the antibacterial rate against Staphylococcus aureus (ATCC 6538 or ATCC 27217) and Escherichia coli (8099 or ATCC 25922) was detected. The data are shown in the table below.

[0034]

[0035]

[0036] Skin irritation test (HRIPT): The specific methods and results are shown in the following table.

[0037]

[0038] The formula of Example 1 demonstrates its mildness and high antibacterial efficacy.

[0039] Embodiment 2:

[0040] Provided is a mild hand sanitizer combination with high efficiency and antibacterial effect, which is composed of water, surfactant, moisturizer, lactic acid, chelating agent, preservative, etc. The content of each component is as follows: by mass percentage, water balance, AES 7%, CAB 2%, CMEA 0.7%, glycerol 1.2%, propylene glycol 1%, butylene glycol 0.5%, lactic acid 2%, EDTA-2Na 0.1%, sodium citrate 0.8%, sodium gluconate 0.7%, kason 0.0001%, DMDM ​​H 0.2%, sodium benzoate 0.1%, phenoxyethanol 0.6%. The production process is the same as that of Example 1.

[0041] Embodiment three:

[0042] Provided is a mild hand sanitizer combination with high efficiency and antibacterial effect, which is composed of water, surfactant, moisturizer, lactic acid, chelating agent, preservative, etc. The content of each component is as follows: by mass percentage, water balance, AES 8%, CAB 1.2%, CMEA 0.4%, glycerol 1.6%, propylene glycol 0.5%, butylene glycol 0.3%, lactic acid 3.6%, EDTA-2Na 0.13%, sodium citrate 1%, sodium gluconate 0.4%, kason 0.0002%, DMDM ​​H 0.02%, sodium benzoate 0.3%, phenoxyethanol 0.3%. The production process is the same as that of Example 1.

[0043] The technical solution can clean the skin of the hands, inhibit the growth of bacteria, keep the skin clean and breathable, and is non-irritating to the skin, making the skin of the hands more comfortable and healthy, without using commonly used antibacterial agents such as quaternary ammonium salts, biguanides, alcohols, chlorine-containing compounds, (iso)thiazoles, halides, organic metal compounds, phenols, pyridines, imidazole halogenated alkyls, silver, copper, zinc and other metals or their ions. It has strong stability, few side effects, high safety, and is widely used.

[0044] The mild hand sanitizer combination with high-efficiency antibacterial effect of the present invention reduces the pH value of the system by lactic acid, so that bacteria are placed under the condition of pH 4-5 where it is not easy to grow, but is mild to the hands and does not cause irritation. At the same time, it can inhibit the growth of bacteria, thereby achieving the purpose of cleaning the hand skin, keeping the skin clean and moisturized, with little side effects and high safety.

[0045] The above technical solutions only reflect the preferred technical solutions of the technical solutions of the present invention. Some changes that may be made to certain parts thereof by technicians in this technical field all reflect the principles of the present invention and fall within the protection scope of the present invention.

Claims

1. A mild hand sanitizer with high antibacterial effect, characterized in that: The composition includes the following components: water, surfactant, humectant, lactic acid, chelating agent and preservative.

2. A mild hand washing liquid with high efficiency and antibacterial effect according to claim 1, characterized in that: The components are as follows according to mass percentage: water balance, surfactant 7-10%, moisturizer 0.5-3%, lactic acid 0.2-4%, chelating agent 0.05-2%, and preservative 0.05-1%.

3. A mild hand washing liquid with high efficiency and antibacterial effect according to claim 1, characterized in that: The surfactant is a mixture of one or more of AES (sodium laureth sulfate), CAB (cocamidopropyl betaine), and CMEA (cocamide MEA).

4. A mild hand washing liquid with high efficiency and antibacterial effect according to claim 3, characterized in that: The source of the AES (sodium laureth sulfate) is obtained by synthesis, the source of CAB (cocamidopropyl betaine) is obtained by synthesis, and the source of CMEA (cocamide MEA) is obtained by synthesis.

5. A mild hand washing liquid with high efficiency and antibacterial effect according to claim 1, characterized in that: The moisturizing agent is a mixture of one or more of glycerol, propylene glycol and butylene glycol.

6. A mild hand washing liquid with high efficiency and antibacterial effect according to claim 5, characterized in that: The glycerol is obtained from saponification byproducts, the propylene glycol is obtained from synthesis, and the butylene glycol is obtained from synthesis.

7. A mild hand washing liquid with high efficiency and antibacterial effect according to claim 1, characterized in that: The lactic acid is obtained from fermentation.

8. A mild hand washing liquid with high efficiency and antibacterial effect according to claim 1, characterized in that: The chelating agent is a mixture of one or more of EDTA-2Na, sodium citrate, and sodium gluconate, and the preservative is a mixture of one or more of kasone, DMDMH (DMDM hydantoin), sodium benzoate, and phenoxyethanol.

9. A mild hand washing liquid with high efficiency and antibacterial effect according to claim 8, characterized in that: The source of the EDTA-2Na is obtained by synthesis, the source of the sodium citrate is obtained by synthesis, and the source of the sodium gluconate is obtained by synthesis.

10. Use of a mild hand soap with high antibacterial effect as claimed in any one of claims 1 to 9 in cosmetics and personal care products.

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