Injection device with fixed point function and use method thereof

Abstract

The invention discloses an injection device with a point fixing function and a using method thereof.The injection device comprises a bottom plate, a mouse placing device is installed on the left side of the bottom plate, body shape adjusting devices are installed on the front side and the rear side of the mouse placing device correspondingly, and a body length adjusting device is installed on the left side of the mouse placing device; a mouse placing device is installed on the right side of the bottom plate, a tail pre-fixing device is installed on the right side of the mouse placing device, a clamping point fixing device is installed on the right side of the bottom plate and comprises a height adjusting mechanism, a secondary clamping assembly and a rapid point fixing mechanism, the height adjusting mechanism is installed on the right side of the bottom plate, and the secondary clamping assembly is installed on the left side of the height adjusting mechanism. The rapid point fixing mechanism is installed on the right side of the height adjusting mechanism. By means of the mode, the mouse tail vein fixing device can be rapidly adjusted according to the body type of a mouse, fixed-point positioning can be rapidly conducted on the mouse tail vein, and the height can be adjusted to adapt to the terrain clearance of different mouse tails.

Description

Technical Field

[0001] The invention relates to the technical field of mouse experimental equipment, in particular to an injection device with a fixed-point function and a use method thereof. Background Art

[0002] Mouse tail vein injection is usually used for drug injection experiments and disease model establishment. In pharmacological research, it is often necessary to inject drugs into mice through tail vein injection to study the drug's efficacy, pharmacokinetics and other properties. For example, in the process of new drug development, candidate drugs are injected into mice through tail vein injection, and then the physiological reactions of mice and the metabolic process of drugs in the body are observed. Therefore, the tail of the mouse needs to be fixed for injection experiments. When the needle enters the vein, there will be a slight sense of emptiness, and blood can be seen returning to the syringe. At this time, the syringe piston can be slowly pushed to inject the drug solution into the tail vein. The injection speed should not be too fast to avoid rupturing the vein or causing adverse reactions in mice. After the injection is completed, slowly pull out the needle and press the injection site with a cotton ball for a moment to prevent bleeding.

[0003] Chinese patent CN217828148U proposes a fixing device for mouse tail vein injection, including a base, a cylinder, a limiting cylinder and a limiting plate, wherein the cylinder is horizontally fixed on the base, the tail end of the cylinder is open, the limiting cylinder is inserted into the cylinder from the tail end of the cylinder, the front end of the limiting cylinder is open, the limiting plate is arranged at the tail end opening of the limiting cylinder, and a limiting plate bottom hole is opened at the bottom end of the limiting plate, and the limiting plate bottom hole is used to leak the mouse's tail for intravenous injection. The mouse's tail can be well protected by the limiting cylinder rubber pad and the limiting plate rubber pad, thereby ensuring a good experimental fixation effect while protecting animal welfare.

[0004] However, the technical solution of this patent has the following problems:

[0005] 1. This patent can well protect the tail of mice through the limiting tube rubber pad and the limiting plate rubber pad, and ensure a good experimental fixation effect under the premise of protecting animal welfare, but it cannot be quickly adjusted according to the body shape of the mouse, and the height cannot be adjusted to fix the tail of mice of different heights.

[0006] 2. This patent cannot be quickly adjusted to locate the tail vein, and the working efficiency is low.

[0007] Based on this, the present invention designs an injection device with a fixed-point function and a method of using the same to solve the above problems. Summary of the invention

[0008] In view of the above-mentioned shortcomings of the prior art, the present invention provides an injection device with a fixed-point function and a method for using the same.

[0009] To achieve the above objectives, the present invention is implemented through the following technical solutions:

[0010] An injection device with a fixed-point function comprises a base plate, a mouse placing device is installed on the left side of the base plate, body shape adjustment devices are installed on both the front and rear sides of the mouse placing device, a body length adjustment device is installed on the left side of the mouse placing device, a tail pre-fixing device is installed on the right side of the mouse placing device, a clamping fixed-point device is installed on the right side of the base plate, the clamping fixed-point device comprises: a height adjustment mechanism, a secondary clamping assembly and a quick fixed-point mechanism, the height adjustment mechanism is installed on the right side of the base plate, the secondary clamping assembly is installed on the left side of the height adjustment mechanism, and the quick fixed-point mechanism is installed on the right side of the height adjustment mechanism.

[0011] Furthermore, the height adjustment mechanism includes: a first guide rod, a support plate, a threaded rod, a first bevel gear and an adjustment assembly, a plurality of the first guide rods are slidably connected to the right side of the base plate, the support plate is fixedly installed on the upper side of the first guide rod, the upper side of the threaded rod is rotatably connected to the lower side of the support plate, the first bevel gear is rotatably connected to the base plate, the lower side of the threaded rod is threadedly connected to the first bevel gear, and the two adjustment assemblies are symmetrically installed on the lower side of the base plate along the central axis of the first bevel gear.

[0012] Furthermore, the adjustment assembly includes: an extension rod and a second bevel gear, the extension rod is rotatably connected to the lower side of the base plate, the second bevel gear is fixedly mounted on one end of the extension rod close to the first bevel gear, and the second bevel gear and the first bevel gear are meshed with each other.

[0013] Furthermore, the secondary clamping assembly includes: a rotating splint and a silicone pad. The rotating splint is rotatably connected to the left side of the support plate through a damping shaft. An arc-shaped groove is provided on the rotating splint. A silicone pad is fixedly installed in the arc-shaped groove to isolate the mouse tail and the rotating splint to prevent the rotating splint from scratching the mouse tail and causing stress to the mouse.

[0014] Furthermore, the rapid positioning mechanism includes: a transparent plate, a scale, a sliding rod and an LED light, a strip groove is provided on the middle side of the support plate, the transparent plate is fixedly mounted on the strip groove, the scale is fixedly mounted on the upper side of the support plate, the scale is arranged on the rear side of the transparent plate, the sliding rod is slidably connected in the strip groove, the LED light is fixedly mounted on the left side of the sliding rod, and the LED light is electrically connected to an external controller.

[0015] Furthermore, the mouse placement device includes: a circular shell, a first magnet and an iron sheet, a plurality of protrusions are arranged on the lower side of the circular shell, a plurality of circular grooves are arranged on the bottom plate, the protrusions on the lower side of the circular shell are arranged in the circular grooves, a first magnet is fixedly installed in each of the protrusions, an iron sheet is fixedly installed in each of the circular grooves, a first slot is arranged on the upper side of the circular shell, and a second slot is arranged on the right side of the circular shell.

[0016] Furthermore, the body shape adjustment device includes: an arc plate, a sliding bracket, a vertical sliding rod and a second magnet, the arc plate is arranged in a circular shell, the sliding bracket is slidably connected to the side wall of the circular shell, the arc plate is fixedly installed on one end of the sliding bracket close to the center of the circular shell, the upper side of the vertical sliding rod is slidably connected to the middle side of the sliding bracket, the second magnet is fixedly installed on the bottom plate, the second magnet is arranged on the lower side of the vertical sliding rod, and the vertical sliding rod can be set to any one of iron, cobalt, nickel and their alloys, so that the vertical sliding rod can be attracted by the second magnet.

[0017] Furthermore, the body length adjustment device includes: a sliding circular frame, a shading cloth and an adjusting nut, the sliding circular frame is slidably connected to the first slot, the shading cloth is fixedly installed on the left side of the sliding circular frame, and the adjusting nut is threadedly connected to the upper side of the sliding circular frame.

[0018] Furthermore, the tail pre-fixing device includes: a fixing plate and a limiting cylinder, the fixing plate is slidably connected to the second slot, and a plurality of limiting cylinders are fixedly installed on the lower side of the fixing plate to limit the upward movement distance of the fixing plate so that it will not move out of the circular shell.

[0019] In order to better achieve the purpose of the present invention, the present invention also provides a method of an injection device with a fixed-point function, comprising the following steps:

[0020] Step 1: Pick up the circular shell of the mouse placement device, move the fixing plate of the tail pre-fixing device, open the fixing plate, put the mouse head in from the fixing plate position of the circular shell, so that the mouse enters the circular shell as a whole, place the mouse tail in the third slot on the fixing plate, close the fixing plate, and preliminarily fix the mouse tail in the third slot;

[0021] Step 2: Put the circular shell back on the bottom plate, move the sliding circular frame left and right, guide the shading cloth on the left side of the sliding circular frame onto the mouse head, tighten the adjustment nut to fix the sliding circular frame, and constrain the length and size of the mouse;

[0022] Step 3: Rotate the rotating clamp plate, and the arc-shaped slot of the rotating clamp plate further clamps the mouse tail. Place the mouse tail on the transparent plate, and observe the approximate length of the mouse tail through the scale on the back of the transparent plate, and pre-judge the mouse tail vein injection point, and move the sliding rod left and right. The left and right movement of the sliding rod drives the LED light to move left and right. According to the pre-judged approximate position of the mouse tail vein injection point, move the LED light to its approximate position, and control the light intensity of the LED light through the external controller to find the appropriate light intensity to observe the mouse tail vein. Next, move the sliding rod left and right to further confirm the mouse tail vein injection point;

[0023] Step 4: After finding a suitable intravenous injection point, perform intravenous injection on the mouse. After the injection, open the rotating splint, pick up the round shell, open the fixing plate and release the mouse.

[0024] Compared with the prior art, the beneficial effects of the present invention are as follows: 1. The present invention drives the arc plate and the vertical slide bar to move forward and backward at the same time by moving the movable bracket and the sliding bracket forward and backward. The arc plate moves forward and backward to limit the front and rear directions of the mouse. The vertical slide bar is adsorbed on the second magnet, which is conducive to stepless adjustment of the sliding bracket and quick fixation of the arc plate at the same time to adapt to the body shapes of different mice, and can be quickly adjusted according to the body shapes of the mice; the sliding circular frame is moved left and right to guide the shading cloth on the left side of the sliding circular frame onto the head of the mouse. The shading cloth is conducive to shielding the light from the eyes of the mouse, which is used to soothe some breeds of mice, improve the success rate of injection, and is conducive to adapting to the body lengths of different mice;

[0025] 2. Open the fixing plate, put the mouse head into the circular shell from the fixing plate position direction, so that the mouse enters the circular shell as a whole, place the mouse tail in the third slot on the fixing plate, close the fixing plate, and preliminarily fix the mouse tail in the third slot, which is conducive to pre-fixing the mouse tail. Place the mouse tail on the transparent plate, observe the approximate length of the mouse tail through the scale on the back of the transparent plate to pre-judge the mouse tail vein injection point, move the sliding rod left and right, and the sliding rod moves left and right to drive the LED light to move left and right. According to the pre-judged approximate position of the mouse tail vein injection point, move the LED light to its approximate position, control the light intensity of the LED light through the external controller, find the appropriate light intensity to observe the mouse tail vein, and then move the sliding rod left and right to further confirm the mouse tail vein injection point, which is conducive to quickly positioning the mouse tail vein;

[0026] 3. The extension rod of the adjusting assembly of the height adjustment mechanism rotates to drive the second bevel gear to rotate, and the rotation of the second bevel gear drives the first bevel gear to rotate. The rotation of the first bevel gear causes the threaded rod to move up and down on the first bevel gear. The up and down movement of the threaded rod drives the support plate to move up and down, which is conducive to adjusting the height to adapt to the height of the tail of different mice from the ground. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the prior art descriptions are briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention, and for ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0028] Figure 1 The three-dimensional structure of the present invention is shown in FIG. Figure 1 ;

[0029] Figure 2 It is a front view of the present invention;

[0030] Figure 3 The three-dimensional structure of the present invention is shown in FIG. Figure 2 ;

[0031] Figure 4 The three-dimensional structure of the present invention is shown in FIG. Figure 3 ;

[0032] Figure 5 The three-dimensional structure of the present invention is shown in FIG. Figure 4 ;

[0033] Figure 6 It is an overall cross-sectional view of the present invention;

[0034] Figure 7 The structure diagram of the mouse of the present invention is shown in the following figure. Figure 1 ;

[0035] Figure 8 The structure diagram of the mouse of the present invention is shown in the following figure. Figure 2 ;

[0036] Fig. 9 for Figure 8 A is an enlarged view of the middle image.

[0037] The numbers in the figure represent:

[0038] 1. Base plate; 2. Mouse placement device; 21. Round shell; 22. First magnet; 23. Iron sheet; 3. Body shape adjustment device; 31. Arc plate; 32. Sliding bracket; 33. Vertical slide rod; 34. Second magnet; 4. Body length adjustment device; 41. Sliding round frame; 42. Shading cloth; 43. Adjusting nut; 5. Tail pre-fixing device; 51. Fixing plate; 52. Limiting cylinder: 6. Clamping fixed point device; 61. First guide rod; 62. Support plate; 63. Threaded rod; 64. First bevel gear; 65. Adjusting assembly; 66. Extension rod; 67. Second bevel gear; 68. Rotating splint; 69. Silicone pad; 610. Transparent plate; 611. Scale; 612. Sliding rod; 613. LED light; 7. First slot; 8. Second slot. DETAILED DESCRIPTION

[0039] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0040] The present invention will be further described below in conjunction with the embodiments.

[0041] The terms “left”, “right”, “front”, “back”, “up” and “down” mentioned in the following description are oriented in the viewing direction of the front view.

[0042] Embodiment 1: In some embodiments, please refer to Figure 1-Figure 9 , an injection device with a fixed-point function, comprising a base plate 1, a mouse placing device 2 is installed on the left side of the base plate 1, body shape adjustment devices 3 are installed on the front and rear sides of the mouse placing device 2, a body length adjustment device 4 is installed on the left side of the mouse placing device 2, a tail pre-fixing device 5 is installed on the right side of the mouse placing device 2, a clamping fixed-point device 6 is installed on the right side of the base plate 1, and the clamping fixed-point device 6 includes: a height adjustment mechanism, a secondary clamping assembly and a quick fixed-point mechanism, the height adjustment mechanism is installed on the right side of the base plate 1, the secondary clamping assembly is installed on the left side of the height adjustment mechanism, and the quick fixed-point mechanism is installed on the right side of the height adjustment mechanism.

[0043] The mouse placement device 2 is used to place mice. The body shape adjustment device 3 and the body length adjustment device 4 can be adjusted according to the body shapes of different mice to adapt to different mice, so as to ensure that the mice have a minimum range of activity in the mouse placement device 2 to avoid affecting the tail vein injection. The tail pre-fixing device 5 pre-fixes the end of the mouse's tail to reduce the swinging range of the mouse's tail. The height adjustment mechanism of the clamping and fixing device 6 adjusts the height to adapt to the height of the mouse's tail from the ground. The secondary clamping component further clamps the middle side of the mouse's tail to further reduce the swinging range of the mouse's tail. The rapid fixing mechanism is used to quickly fix the mouse's tail vein.

[0044] The height adjustment mechanism includes: a first guide rod 61, a support plate 62, a threaded rod 63, a first bevel gear 64 and an adjustment assembly 65. Multiple first guide rods 61 are slidably connected to the right side of the base plate 1, the support plate 62 is fixedly installed on the upper side of the first guide rod 61, the upper side of the threaded rod 63 is rotatably connected to the lower side of the support plate 62, the first bevel gear 64 is rotatably connected to the base plate 1, and the lower side of the threaded rod 63 is threadedly connected to the first bevel gear 64. Two adjustment assemblies 65 are symmetrically installed on the lower side of the base plate 1 along the central axis of the first bevel gear 64.

[0045] The adjustment assembly 65 includes: an extension rod 66 and a second bevel gear 67. The extension rod 66 is rotatably connected to the lower side of the base plate 1. The second bevel gear 67 is fixedly mounted on one end of the extension rod 66 close to the first bevel gear 64. The second bevel gear 67 and the first bevel gear 64 are meshed with each other.

[0046] The extension rod 66 of the adjustment component 65 of the height adjustment mechanism rotates to drive the second bevel gear 67 to rotate, and the second bevel gear 67 rotates to drive the first bevel gear 64 to rotate. The rotation of the first bevel gear 64 causes the threaded rod 63 to move up and down on the first bevel gear 64. The up and down movement of the threaded rod 63 drives the support plate 62 to move up and down, which is conducive to adjusting the height to adapt to the height of the tail of different mice from the ground.

[0047] The secondary clamping assembly includes: a rotating splint 68 and a silicone pad 69. The rotating splint 68 is rotatably connected to the left side of the support plate 62 through a damping shaft. An arc-shaped groove is provided on the rotating splint 68. A silicone pad 69 is fixedly installed in the arc-shaped groove to isolate the mouse tail and the rotating splint 68, so as to prevent the rotating splint 68 from scratching the mouse tail and causing stress to the mouse.

[0048] The rotating clamping plate 68 is rotated, and the arc-shaped slot of the rotating clamping plate 68 further clamps the mouse tail, which is beneficial to further fix the mouse tail and reduce the swing range of the mouse tail.

[0049] The rapid positioning mechanism includes: a transparent plate 610, a scale 611, a sliding rod 612 and an LED lamp 613. A strip groove is provided on the middle side of the support plate 62. The transparent plate 610 is fixedly mounted on the strip groove. The scale 611 is fixedly mounted on the upper side of the support plate 62. The scale 611 is arranged on the rear side of the transparent plate 610. The sliding rod 612 is slidably connected in the strip groove. The LED lamp 613 is fixedly mounted on the left side of the sliding rod 612. The LED lamp 613 is electrically connected to an external controller.

[0050] Place the mouse tail on the transparent plate 610, observe the approximate length of the mouse tail through the scale 611 on the rear side of the transparent plate 610 to pre-judge the mouse tail vein injection point, move the sliding rod 612 left and right, and the sliding rod 612 left and right moves the LED light 613 left and right. According to the pre-judged approximate position of the mouse tail vein injection point, move the LED light 613 to its approximate position, control the light intensity of the LED light 613 through an external controller, find the appropriate light intensity to observe the mouse tail vein, and then move the sliding rod 612 left and right to further confirm the mouse tail vein injection point, which is conducive to quickly positioning the mouse tail vein.

[0051] Embodiment 2: In some embodiments, Figure 1-Figure 9 As shown, as a preferred embodiment of the present invention, the mouse placement device 2 includes: a circular shell 21, a first magnet 22 and an iron sheet 23, the circular shell 21 is provided with a plurality of protrusions on the lower side, the bottom plate 1 is provided with a plurality of circular grooves, the protrusions on the lower side of the circular shell 21 are arranged in the circular grooves, each of the protrusions is fixedly installed with the first magnet 22, each of the circular grooves is fixedly installed with the iron sheet 23, the upper side of the circular shell 21 is provided with a first slot 7, the right side of the circular shell 21 is provided with a second slot 8, and the circular shell 21 is fixed by the attraction of the first magnet 22 to the iron sheet 23.

[0052] The body shape adjustment device 3 includes: an arc plate 31, a sliding bracket 32, a vertical sliding rod 33 and a second magnet 34. The arc plate 31 is arranged in the circular shell 21, and the sliding bracket 32 ​​is slidably connected to the side wall of the circular shell 21. The arc plate 31 is fixedly installed at one end of the sliding bracket 32 ​​close to the center of the circular shell 21. The upper side of the vertical sliding rod 33 is slidably connected to the middle side of the sliding bracket 32. The second magnet 34 is fixedly installed on the bottom plate 1. The second magnet 34 is arranged on the lower side of the vertical sliding rod 33. The vertical sliding rod 33 can be set to any one of iron, cobalt, nickel and their alloys, so that the vertical sliding rod 33 can be attracted by the second magnet 34.

[0053] The sliding bracket 32 ​​moves forward and backward, and the sliding bracket 32 ​​drives the arc plate 31 and the vertical slide bar 33 to move forward and backward at the same time. The arc plate 31 moves forward and backward to limit the front and back directions of the mouse. The vertical slide bar 33 is adsorbed on the second magnet 34, which is conducive to stepless adjustment of the sliding bracket 32 ​​and quick fixation of the arc plate 31 at the same time to adapt to the body shapes of different mice.

[0054] The body length adjustment device 4 includes: a sliding circular frame 41, a shading cloth 42 and an adjusting nut 43. The sliding circular frame 41 is slidably connected to the first slot 7, the shading cloth 42 is fixedly installed on the left side of the sliding circular frame 41, and the adjusting nut 43 is threadedly connected to the upper side of the sliding circular frame 41.

[0055] Move the sliding circular frame 41 left and right, and guide the shading cloth 42 on the left side of the sliding circular frame 41 onto the mouse head. The shading cloth 42 is helpful to block the light from the mouse eyes, which is used to soothe some species of mice, improve the injection success rate, and is also helpful to adapt to different mouse body lengths.

[0056] The tail pre-fixing device 5 includes: a fixing plate 51 and a limiting cylinder 52, wherein the fixing plate 51 is slidably connected to the second slot 8, and a plurality of limiting cylinders 52 are fixedly mounted on the lower side of the fixing plate 51 to limit the upward movement distance of the fixing plate 51 so that it does not move out of the circular shell 21, and a third slot is provided on the fixing plate 51 for the mouse tail to pass through.

[0057] Pick up the circular shell 21 of the mouse placement device 2, move the fixing plate 51 of the tail pre-fixing device 5, open the fixing plate 51, put the mouse head in from the position direction of the fixing plate 51 of the circular shell 21, so that the mouse as a whole enters the circular shell 21, place the mouse tail in the third slot on the fixing plate 51, close the fixing plate 51, preliminarily fix the mouse tail in the third slot, move the sliding circular frame 41 left and right, guide the shading cloth 42 on the left side of the sliding circular frame 41 onto the mouse head, the shading cloth 42 is conducive to blocking the light from the mouse's eyes, and is used to soothe some breeds of mice and improve the success rate of injection, tighten the adjusting nut 43 to fix the sliding circular frame 41, which is conducive to restraining the mouse's body length and body shape, so that its range of activities in the circular shell 21 becomes smaller.

[0058] Embodiment 3: In some embodiments, Figure 1-Figure 9 As shown, as a preferred embodiment of the present invention, a method of an injection device with a fixed-point function comprises the following steps:

[0059] Step 1: Pick up the circular shell 21 of the mouse placement device 2, move the fixing plate 51 of the tail pre-fixing device 5, open the fixing plate 51, put the mouse head in from the position direction of the fixing plate 51 of the circular shell 21, so that the mouse enters the circular shell 21 as a whole, place the mouse tail in the third slot on the fixing plate 51, close the fixing plate 51, and preliminarily fix the mouse tail in the third slot;

[0060] Step 2: Put the circular housing 21 back on the bottom plate 1, move the sliding circular frame 41 left and right, guide the shading cloth 42 on the left side of the sliding circular frame 41 onto the mouse head, and tighten the adjusting nut 43 to fix the sliding circular frame 41 to constrain the length and shape of the mouse;

[0061] Step 3: Rotate the rotating clamp 68, the arc-shaped slot of the rotating clamp 68 further clamps the mouse tail, place the mouse tail on the transparent plate 610, observe the approximate length of the mouse tail through the scale 611 on the rear side of the transparent plate 610, pre-judge the mouse tail vein injection point, move the sliding rod 612 left and right, the sliding rod 612 moves left and right to drive the LED light 613 to move left and right, according to the pre-judgement of the approximate position of the mouse tail vein injection point, move the LED light 613 to its approximate position, control the light intensity of the LED light 613 through the external controller, find the appropriate light intensity to observe the mouse tail vein, and then move the sliding rod 612 left and right to further confirm the mouse tail vein injection point;

[0062] Step 4: After finding a suitable intravenous injection point, perform intravenous injection on the mouse. After the injection is completed, open the rotating clamp 68, pick up the circular shell 21, open the fixing plate 51 and release the mouse.

[0063] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit the same. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that the technical solutions described in the aforementioned embodiments may still be modified, or some of the technical features may be replaced by equivalents. Such modifications or replacements will not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. An injection device with a fixed-point function, comprising a base plate (1), characterized in that: A mouse placement device (2) is installed on the left side of the base plate (1), body shape adjustment devices (3) are installed on both the front and rear sides of the mouse placement device (2), a body length adjustment device (4) is installed on the left side of the mouse placement device (2), a tail pre-fixing device (5) is installed on the right side of the mouse placement device (2), and a clamping and fixing device (6) is installed on the right side of the base plate (1). The clamping and fixing device (6) comprises: a height adjustment mechanism, a secondary clamping assembly and a rapid fixing mechanism. The height adjustment mechanism is installed on the right side of the base plate (1), the secondary clamping assembly is installed on the left side of the height adjustment mechanism, and the rapid fixing mechanism is installed on the right side of the height adjustment mechanism.

2. The injection device with fixed-point function according to claim 1, characterized in that: The height adjustment mechanism comprises: a first guide rod (61), a support plate (62), a threaded rod (63), a first bevel gear (64) and an adjustment assembly (65); a plurality of the first guide rods (61) are slidably connected to the right side of the base plate (1); the support plate (62) is fixedly mounted on the upper side of the first guide rod (61); the upper side of the threaded rod (63) is rotatably connected to the lower side of the support plate (62); the first bevel gear (64) is rotatably connected to the base plate (1); the lower side of the threaded rod (63) is threadedly connected to the first bevel gear (64); and two adjustment assemblies (65) are symmetrically mounted on the lower side of the base plate (1) along the central axis of the first bevel gear (64).

3. The injection device with fixed-point function according to claim 2, characterized in that: The adjustment assembly (65) comprises: an extension rod (66) and a second bevel gear (67); the extension rod (66) is rotatably connected to the lower side of the base plate (1); the second bevel gear (67) is fixedly mounted on one end of the extension rod (66) close to the first bevel gear (64); the second bevel gear (67) and the first bevel gear (64) are meshed with each other.

4. The injection device with fixed-point function according to claim 3, characterized in that: The secondary clamping assembly comprises: a rotating clamping plate (68) and a silicone pad (69); the rotating clamping plate (68) is rotatably connected to the left side of the support plate (62) via a damping shaft; an arc-shaped slot is provided on the rotating clamping plate (68), and the silicone pad (69) is fixedly installed in the arc-shaped slot.

5. The injection device with fixed-point function according to claim 4, characterized in that: The rapid positioning mechanism comprises: a transparent plate (610), a scale (611), a sliding rod (612) and an LED lamp (613); a strip groove is arranged on the middle side of the support plate (62); the transparent plate (610) is fixedly mounted on the strip groove; the scale (611) is fixedly mounted on the upper side of the support plate (62); the scale (611) is arranged on the rear side of the transparent plate (610); the sliding rod (612) is slidably connected in the strip groove; the LED lamp (613) is fixedly mounted on the left side of the sliding rod (612); and the LED lamp (613) is electrically connected to an external controller.

6. The injection device with fixed-point function according to claim 5, characterized in that: The mouse placement device (2) comprises: a circular shell (21), a first magnet (22) and an iron sheet (23); a plurality of protrusions are arranged on the lower side of the circular shell (21); a plurality of circular grooves are arranged on the bottom plate (1); the protrusions on the lower side of the circular shell (21) are arranged in the circular grooves; the first magnet (22) is fixedly installed in each of the protrusions; the iron sheet (23) is fixedly installed in each of the circular grooves; a first slot (7) is arranged on the upper side of the circular shell (21); and a second slot (8) is arranged on the right side of the circular shell (21).

7. The injection device with fixed-point function according to claim 6, characterized in that: The body shape adjustment device (3) comprises: an arc plate (31), a sliding bracket (32), a vertical sliding rod (33) and a second magnet (34); the arc plate (31) is arranged in a circular shell (21); the sliding bracket (32) is slidably connected to the side wall of the circular shell (21); the arc plate (31) is fixedly mounted on one end of the sliding bracket (32) close to the center of the circular shell (21); the upper side of the vertical sliding rod (33) is slidably connected to the middle side of the sliding bracket (32); the second magnet (34) is fixedly mounted on the bottom plate (1); and the second magnet (34) is arranged on the lower side of the vertical sliding rod (33).

8. The injection device with fixed-point function according to claim 7, characterized in that: The body length adjustment device (4) comprises: a sliding circular frame (41), a shading cloth (42) and an adjustment nut (43); the sliding circular frame (41) is slidably connected to the first slot (7); the shading cloth (42) is fixedly mounted on the left side of the sliding circular frame (41); and the adjustment nut (43) is threadedly connected to the upper side of the sliding circular frame (41).

9. The injection device with fixed-point function according to claim 8, characterized in that: The tail pre-fixing device (5) comprises: a fixing plate (51) and a limiting cylinder (52); the fixing plate (51) is slidably connected to the second slot (8); and a plurality of limiting cylinders (52) are fixedly mounted on the lower side of the fixing plate (51).

10. A method for an injection device with a fixed-point function, used for the injection device with a fixed-point function according to claim 9, characterized in that: The following steps are involved: Step 1: Pick up the circular shell (21) of the mouse placement device (2), move the fixing plate (51) of the tail pre-fixing device (5), open the fixing plate (51), put the mouse head into the circular shell (21) from the position direction of the fixing plate (51) so that the mouse enters the circular shell (21) as a whole, place the mouse tail in the third slot on the fixing plate (51), close the fixing plate (51), and preliminarily fix the mouse tail in the third slot; Step 2: Place the circular housing (21) back onto the bottom plate (1), move the sliding circular frame (41) left and right, guide the shading cloth (42) on the left side of the sliding circular frame (41) onto the mouse head, and tighten the adjusting nut (43) to fix the sliding circular frame (41) to constrain the length and size of the mouse; Step 3: Rotate the rotating clamp (68), the arc-shaped slot of the rotating clamp (68) further clamps the mouse tail, and place the mouse tail on the transparent plate (610). Observe the approximate length of the mouse tail through the scale (611) on the rear side of the transparent plate (610), pre-judge the mouse tail vein injection point, move the sliding rod (612) left and right, and the sliding rod (612) moves left and right to drive the LED light (613) to move left and right. According to the pre-judgement of the approximate position of the mouse tail vein injection point, move the LED light (613) to its approximate position, control the light intensity of the LED light (613) through the external controller, find the appropriate light intensity to observe the mouse tail vein, and then move the sliding rod (612) left and right to further confirm the mouse tail vein injection point; Step 4: After finding a suitable intravenous injection point, perform intravenous injection on the mouse. After the injection is completed, open the rotating clamp (68), pick up the circular shell (21), open the fixing plate (51) and release the mouse.

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