Femtosecond laser refractive surgery cutting center positioning method and device

Abstract

The invention discloses a femtosecond laser refractive surgery cutting center positioning method and device, and relates to the field of refractive surgery cutting center localization, and the method comprises the steps: obtaining a lying position eye image and a sitting position eye image of a to-be-operated patient under set illumination brightness, and determining a first iris image and a first relative position; determining a second iris image according to the lying position eye image; according to the first iris image and the second iris image, a first eyeball rotation angle is determined, a second visual axis center and a second relative position of the patient to be operated can be further calculated, negative pressure suction is guided, and before negative pressure suction and after the center of a negative pressure suction ring is aligned with the second visual axis center, if movement occurs, the first eyeball rotation angle is determined; a third iris image in the negative pressure suction process is shot, then the center of a third visual axis is calculated, the center of the negative pressure suction ring is aligned to the center of the third visual axis, and the center of the third visual axis serves as the cutting center for operation. The cutting center can be accurately positioned.

Description

Technical Field

[0001] The present application relates to the field of cutting center positioning in refractive surgery, and in particular to a method and device for positioning the cutting center in femtosecond laser refractive surgery. Background Art

[0002] Femtosecond laser refractive lens extraction is a surgery that uses a femtosecond laser to create a stromal lens on the cornea and remove the lens to correct refractive errors such as myopia and astigmatism. The human eye is not a completely regular optical system, and there is usually a certain deviation between the pupil center and the visual axis center. The use of femtosecond laser to make a lens requires the cutting center to be accurately aligned with the visual axis center, but it is easier to observe the visual axis center during surgery. The relative position of the visual axis center and the pupil center can be obtained relatively easily during preoperative examination, so theoretically, the visual axis center can be found according to the relative position and the pupil center during surgery. However, the eyeball rotates in these two postures during preoperative examination and lying position during surgery, and the relative position also changes. In addition, the pupil diameter will also affect the relative position. The relative position relationship between the visual axis center and the pupil center becomes more complicated due to the influence of eyeball rotation and changes in pupil diameter, and it is easy to cause deviations if it is simply based on manual positioning by the doctor. Summary of the invention

[0003] The purpose of this application is to provide a method and device for positioning the cutting center in femtosecond laser refractive surgery, so as to realize automatic positioning of the cutting center and improve positioning accuracy.

[0004] To achieve the above objectives, this application provides the following solutions:

[0005] In a first aspect, the present application provides a method for positioning the cutting center of femtosecond laser refractive surgery, comprising:

[0006] Acquire an eye image of a patient to be operated on in a seated position under a set light illumination, and determine a first iris image and a first relative position; the first relative position is the relative position of a first pupil center and a first visual axis center; the first pupil center is the pupil center of the patient to be operated on when the patient is sitting and looking at a fixation lamp; the first visual axis center is a coaxial reflection point in the eye image of the patient to be operated on in a seated position;

[0007] Acquire an eye image of a patient in a lying position to be operated on under a set light illumination;

[0008] Determining a second iris image and a second pupil center of the patient to be operated on according to the lying eye image;

[0009] determining a first eyeball rotation angle according to the first iris image and the second iris image;

[0010] According to the first pupil center, the first relative position and the first eyeball rotation angle, a second visual axis center of the patient to be operated on is calculated, and a second relative position between the second visual axis center and the second pupil center is calculated; the second visual axis center is the visual axis center of the patient to be operated on in a lying position;

[0011] performing negative pressure suction according to the second relative position guidance;

[0012] Aligning the center of the negative pressure suction ring with the center of the second visual axis, and determining whether the center of the negative pressure suction ring is aligned with the center of the second visual axis;

[0013] If yes, a prompt is given to start negative pressure suction, and a third iris image of the patient to be operated on is obtained under the set light illumination, and a third pupil center is determined;

[0014] According to the first pupil center, the first relative position and the second eyeball rotation angle, the third visual axis center of the patient to be operated on is calculated, and the third relative position between the third visual axis center and the third pupil center is calculated; the second eyeball rotation angle is determined according to the first iris image and the third iris image; the third visual axis center is the visual axis center of the patient to be operated on during the negative pressure suction process;

[0015] Determining whether the center of the negative pressure suction ring is aligned with the center of the third visual axis;

[0016] If so, the third visual axis center is used as the cutting center, and the astigmatism axis of the femtosecond laser equipment cutting model is adjusted according to the second eyeball rotation angle, prompting to start laser scanning.

[0017] Optionally, if not, re-perform vacuum suction.

[0018] Optionally, if not, adjust the center of the femtosecond laser device cutting model to the center of the third visual axis, adjust the astigmatism axis of the cutting model according to the second eyeball rotation angle, and prompt to start laser scanning.

[0019] Optionally, obtaining an eye image of a patient in a sitting position to be operated on under a set light illumination, and determining a first iris image and a relative position, specifically includes:

[0020] Acquire an eye image of a patient in a sitting position to be operated on under a set light illumination;

[0021] Determining a first pupil diameter, a first iris image, a first pupil center, and a first visual axis center of the patient to be operated on according to the sitting eye image;

[0022] A first relative position is determined based on the first pupil center and the first visual axis center.

[0023] Optionally, obtaining an eye image of a patient in a lying position to be operated on under a set light illumination specifically includes:

[0024] The patient to be operated on looks at the fixation light while lying in preparation for the operation;

[0025] Adjusting the light brightness to a set light brightness so that the pupil center of the patient to be operated on coincides with the first pupil center;

[0026] The lying eye image is captured.

[0027] Optionally, determining a first eyeball rotation angle according to the first iris image and the second iris image specifically includes:

[0028] Determine the positions of an inner circle and an outer circle in the first iris image and the second iris image respectively, and obtain a processed first iris image and a processed second iris image; the inner circle is a boundary between the iris and the pupil; the outer circle is a boundary between the iris and the sclera;

[0029] performing normalization processing on the processed first iris image and the processed second iris image respectively to obtain a normalized first iris image and a normalized second iris image;

[0030] performing image enhancement on the normalized first iris image and the normalized second iris image respectively to obtain an enhanced first iris image and an enhanced second iris image;

[0031] Determining a first iris feature point angle according to the enhanced first iris image;

[0032] Determining a second iris feature point angle according to the enhanced second iris image;

[0033] The first eyeball rotation angle is determined according to the first iris feature point angle and the second iris feature point angle.

[0034] Optionally, determining the first eyeball rotation angle according to the first iris feature point angle and the second iris feature point angle specifically includes:

[0035] The first eyeball rotation angle is determined using the formula λ1=α-β1, wherein λ1 is the first eyeball rotation angle; α is the first iris feature point angle; and β1 is the second iris feature point angle.

[0036] Optionally, determining a second eyeball rotation angle according to the first iris image and the third iris image specifically includes:

[0037] Determine the positions of an inner circle and an outer circle in the first iris image and the third iris image, respectively, to obtain a processed first iris image and a processed third iris image; the inner circle is a boundary between the iris and the pupil; the outer circle is a boundary between the iris and the sclera;

[0038] performing normalization processing on the processed first iris image and the processed third iris image respectively to obtain a normalized first iris image and a normalized third iris image;

[0039] performing image enhancement on the normalized first iris image and the normalized third iris image respectively to obtain an enhanced first iris image and an enhanced third iris image;

[0040] Determining a first iris feature point angle according to the enhanced first iris image;

[0041] Determining a third iris feature point angle according to the enhanced third iris image;

[0042] The second eyeball rotation angle is determined according to the first iris feature point angle and the third iris feature point angle.

[0043] Optionally, determining the second eyeball rotation angle according to the first iris feature point angle and the third iris feature point angle specifically includes:

[0044] The second eyeball rotation angle is determined using the formula λ2=α-β2, wherein λ2 is the second eyeball rotation angle; α is the first iris feature point angle; and β2 is the third iris feature point angle.

[0045] In a second aspect, the present application provides a computer program product, including a computer program, which, when executed by a processor, implements any of the above-mentioned methods for positioning the cutting center of femtosecond laser refractive surgery.

[0046] According to the specific embodiments provided in this application, this application discloses the following technical effects:

[0047] The present application provides a method and device for positioning the cutting center of a femtosecond laser refractive surgery, which obtains an eye image of a patient in a lying position and a sitting position under a set light illumination, and determines a first iris image and a first relative position; determines a second iris image based on the eye image in the lying position; determines a first eyeball rotation angle based on the first iris image and the second iris image, and can further calculate the second visual axis center and the second relative position of the patient in the surgery, and guides the negative pressure suction. Before the negative pressure suction, after the center of the negative pressure suction ring is aligned with the second visual axis center, if movement occurs, a third iris image is taken during the negative pressure suction process, and then the third visual axis center is calculated, the center of the negative pressure suction ring is aligned to the third visual axis center, and the third visual axis center is used as the cutting center for surgery. The present application improves the accuracy of positioning the cutting center by determining the visual axis center of the patient in the lying position for surgery and using the visual axis center as the cutting center for femtosecond laser refractive surgery. BRIEF DESCRIPTION OF THE DRAWINGS

[0048] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0049] Figure 1 A schematic diagram of a process flow of a femtosecond laser refractive surgery cutting center positioning method provided in one embodiment of the present application;

[0050] Figure 2 A schematic diagram of the structure of a computer device provided in one embodiment of the present application. DETAILED DESCRIPTION

[0051] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0052] In order to make the above-mentioned objects, features and advantages of the present application more obvious and easy to understand, the present application is further described in detail below with reference to the accompanying drawings and specific implementation methods.

[0053] There is usually a certain deviation between the pupil center and the visual axis center of the human eye. When using femtosecond laser to make a lens, the cutting center needs to be accurately aligned with the visual axis center. The relative position relationship between the visual axis center and the pupil center becomes more complicated due to the influence of eye rotation and pupil diameter change. It is easy to cause deviations if it only relies on manual positioning by a doctor. The present invention provides a method for accurately locating the visual axis center point as the center of corneal stroma lens for femtosecond laser scanning to improve the accuracy of cutting center positioning in femtosecond laser refractive surgery.

[0054] In order to accurately position the needs, corresponding adjustments are made. For doctors with high requirements, this application provides a method for positioning the cutting center of femtosecond laser refractive surgery.

[0055] In an exemplary embodiment, Figure 1 As shown, a method for positioning the cutting center of femtosecond laser refractive surgery is provided, comprising the following steps:

[0056] S1: Acquire an eye image of a patient in a sitting position under a set light illumination, and determine a first iris image and a first relative position; the first relative position is the relative position of a first pupil center and a first visual axis center.

[0057] As an optional implementation, S1 specifically includes:

[0058] Acquire an eye image of the patient in the seated position for surgery at a set light intensity.

[0059] Based on the sitting eye image, a first pupil diameter, a first iris image, a first pupil center and a first visual axis center of the patient to be operated on are determined.

[0060] A first relative position is determined based on the first pupil center and the first visual axis center.

[0061] S2: Acquire an eye image of a patient in a lying position to be operated on under a set light illumination.

[0062] As an optional implementation, S2 specifically includes:

[0063] The patient to be operated on looks at the fixation light while lying in preparation for the operation.

[0064] The light brightness is adjusted to a set light brightness so that the pupil center of the patient to be operated on is consistent with the first pupil center.

[0065] The lying eye image is captured.

[0066] S3: Determine a second iris image and a second pupil center of the patient to be operated on according to the lying eye image.

[0067] S4: Determine a first eyeball rotation angle according to the first iris image and the second iris image.

[0068] As an optional implementation, S4 specifically includes:

[0069] Determine the positions of the inner circle and the outer circle in the first iris image and the second iris image respectively, and obtain the processed first iris image and the processed second iris image; the inner circle is the boundary between the iris and the pupil; the outer circle is the boundary between the iris and the sclera.

[0070] The processed first iris image and the processed second iris image are respectively normalized to obtain a normalized first iris image and a normalized second iris image.

[0071] Image enhancement is performed on the normalized first iris image and the normalized second iris image to obtain an enhanced first iris image and an enhanced second iris image.

[0072] The angle of the first iris feature point is determined according to the enhanced first iris image.

[0073] The second iris feature point angle is determined according to the enhanced second iris image.

[0074] Determining the first eyeball rotation angle according to the first iris feature point angle and the second iris feature point angle specifically includes:

[0075] The first eyeball rotation angle is determined using the formula λ1=α-β1, wherein λ1 is the first eyeball rotation angle; α is the first iris feature point angle; and β1 is the second iris feature point angle.

[0076] S5: Calculate the second visual axis center of the patient to be operated on according to the first pupil center, the first relative position and the first eyeball rotation angle, and calculate the second relative position between the second visual axis center and the second pupil center; the second visual axis center is the visual axis center of the patient to be operated on. When the patient lies and looks at the fixation light directly above, the coaxial reflection point in the image (this point is at the very center of the image when the patient fixates on the fixation light directly in the center) is the visual axis center by default.

[0077] S6: Perform negative pressure suction according to the second relative position guidance.

[0078] S7: aligning the center of the negative pressure suction ring with the center of the second visual axis, and determining whether the center of the negative pressure suction ring is aligned with the center of the second visual axis.

[0079] S8: If yes, then start the negative pressure suction, obtain the third iris image of the patient to be operated under the set light brightness, and determine the third pupil center. In order to determine whether the visual axis center shifts during the negative pressure suction process, it is necessary to take the third iris image and perform the following steps.

[0080] S9: Calculate the third visual axis center of the patient to be operated on according to the first pupil center, the first relative position and the second eyeball rotation angle, and calculate the third relative position between the third visual axis center and the third pupil center; the second eyeball rotation angle is determined according to the first iris image and the third iris image; the third visual axis center is the visual axis center of the patient to be operated on during the negative pressure suction process. The calculation principle of the second eyeball rotation angle is consistent with the calculation principle of the first eyeball rotation angle.

[0081] As an optional implementation manner, determining the second eyeball rotation angle according to the first iris image and the third iris image specifically includes:

[0082] Determine the positions of the inner circle and the outer circle in the first iris image and the third iris image respectively, and obtain the processed first iris image and the processed third iris image; the inner circle is the boundary between the iris and the pupil; the outer circle is the boundary between the iris and the sclera.

[0083] The processed first iris image and the processed third iris image are respectively normalized to obtain a normalized first iris image and a normalized third iris image.

[0084] Image enhancement is performed on the normalized first iris image and the normalized third iris image to obtain an enhanced first iris image and an enhanced third iris image.

[0085] The angle of the first iris feature point is determined according to the enhanced first iris image.

[0086] The angle of the third iris feature point is determined according to the enhanced third iris image.

[0087] Determining the second eyeball rotation angle according to the first iris feature point angle and the third iris feature point angle specifically includes:

[0088] The second eyeball rotation angle is determined using the formula λ2=α-β2, wherein λ2 is the second eyeball rotation angle; α is the first iris feature point angle; and β2 is the third iris feature point angle.

[0089] S10: Determine whether the center of the negative pressure suction ring is aligned with the center of the third visual axis.

[0090] S11: If yes, the third visual axis center is used as the cutting center, and the astigmatism axis of the femtosecond laser device cutting model is adjusted according to the second eyeball rotation angle, and a prompt is given to start laser scanning.

[0091] If not, perform negative pressure suction again, or adjust the center of the cutting model of the femtosecond laser equipment to the center of the third visual axis, adjust the astigmatism axis of the cutting model according to the second eye rotation angle, and prompt to start laser scanning.

[0092] So far, a relatively clear and reliable third visual axis center point, that is, the cutting center, has been obtained. The rotation angle of the eyeball when the patient lies in preparation for surgery has also been determined, providing an accurate reference for the cutting center and rotation angle for the next step of laser cutting treatment.

[0093] The femtosecond laser refractive surgery cutting center positioning method of the present application is specifically described below:

[0094] Step 1: Obtain the relative position of the patient to be operated on, and record the light brightness, the first pupil diameter and the first iris image.

[0095] Step 2: Let the patient to be operated on turn on the fixation light, and let the patient lie down. Adjust the light brightness so that the diameter of the second pupil is consistent with the diameter of the first pupil in the sitting position.

[0096] Step 3: Let the patient to be operated look at the fixation light, take an eye image in the lying position, and compare it with the eye image in the sitting position to obtain the first eye rotation angle.

[0097] In this embodiment, femtosecond laser refractive surgery is performed using a VISX STAR S4 excimer laser device, which determines the eye rotation angle based on the eye rotation angle acquisition method described in "Wavefront-Guided Refractive Surgery".

[0098] Step 4: Let the patient to be operated look at the fixation light, identify the second pupil center, and locate the second visual axis center and the second relative position between the second visual axis center and the second pupil center based on the eyeball rotation angle and the first relative position.

[0099] Step 5: Confirm that the patient to be operated on is looking at the fixation light, move the laser emission window closer to the eyeball, and perform negative pressure suction according to the second relative position guidance.

[0100] Step 6: Before starting the negative pressure suction, determine whether the center of the negative pressure suction ring is aligned with the center of the second visual axis. If so, execute step 7.

[0101] Step seven: start negative pressure suction. In order to determine whether the center of the visual axis shifts during the negative pressure suction process, obtain the third iris image of the patient to be operated on under the set light illumination and determine the third pupil center.

[0102] Step 8: Calculate the third visual axis center of the patient to be operated on according to the first pupil center, the first relative position and the second eyeball rotation angle, and calculate the third relative position between the third visual axis center and the third pupil center. The calculation principle of the second eyeball rotation angle is the same as the calculation principle of the first eyeball rotation angle.

[0103] Step 9: Determine whether the center of the negative pressure suction ring is aligned with the center of the third visual axis, if so, proceed to step 10. If the center of the negative pressure suction ring is aligned with the center of the third visual axis, it means that the center of the visual axis has not shifted during the negative pressure suction process, and the operation can be performed.

[0104] Step 10: Use the third visual axis center as the cutting center, adjust the astigmatism axis of the femtosecond laser equipment cutting model according to the second eyeball rotation angle, and prompt to start laser scanning to perform femtosecond laser surgery.

[0105] This application realizes precise positioning of the visual axis center and achieves the expected precise correction effect.

[0106] In an exemplary embodiment, a computer device is provided. The computer device may be a server or a terminal. The internal structure diagram thereof may be as follows: Figure 2 As shown. The computer device includes a processor, a memory, an input / output interface (Input / Output, referred to as I / O) and a communication interface. The processor, the memory and the input / output interface are connected through a system bus, and the communication interface is connected to the system bus through the input / output interface. The processor of the computer device is used to provide computing and control capabilities. The memory of the computer device includes a non-volatile storage medium and an internal memory. The non-volatile storage medium stores an operating system, a computer program and a database. The internal memory provides an environment for the operation of the operating system and the computer program in the non-volatile storage medium. The input / output interface of the computer device is used to exchange information between the processor and an external device. The communication interface of the computer device is used to communicate with an external terminal through a network connection. When the computer program is executed by the processor, a method for positioning the cutting center of femtosecond laser refractive surgery is implemented.

[0107] Those skilled in the art will understand that Figure 2 The structure shown in the figure is only a block diagram of a part of the structure related to the present application scheme, and does not constitute a limitation on the computer device to which the present application scheme is applied. The specific computer device may include more or fewer components than those shown in the figure, or combine certain components, or have a different arrangement of components. In an exemplary embodiment, a computer device is provided, including a memory and a processor, wherein a computer program is stored in the memory, and when the processor executes the computer program, the above-mentioned femtosecond laser refractive surgery cutting center positioning method is implemented.

[0108] In an exemplary embodiment, a computer-readable storage medium is provided, storing a computer program, which, when executed by a processor, implements the above-mentioned method for positioning the cutting center of femtosecond laser refractive surgery.

[0109] In an exemplary embodiment, a computer program product is provided, including a computer program, which, when executed by a processor, implements the above-mentioned femtosecond laser refractive surgery cutting center positioning method.

[0110] It should be noted that the user information (including but not limited to user device information, user personal information, etc.) and data (including but not limited to data used for analysis, stored data, displayed data, etc.) involved in this application are all information and data authorized by the user or fully authorized by all parties, and the collection, use and processing of relevant data must comply with relevant regulations.

[0111] Those of ordinary skill in the art can understand that all or part of the processes in the above-mentioned embodiment methods can be completed by instructing the relevant hardware through a computer program, and the computer program can be stored in a non-volatile computer-readable storage medium. When the computer program is executed, it can include the processes of the embodiments of the above-mentioned methods. Among them, any reference to the memory, database or other medium used in the embodiments provided in the present application can include at least one of non-volatile and volatile memory. Non-volatile memory can include read-only memory (ROM), magnetic tape, floppy disk, flash memory, optical memory, high-density embedded non-volatile memory, resistive random access memory (ReRAM), magnetic random access memory (MRAM), ferroelectric random access memory (FRAM), phase change memory (PCM), graphene memory, etc. Volatile memory can include random access memory (RAM) or external cache memory, etc. By way of illustration and not limitation, RAM may be in various forms, such as static random access memory (SRAM) or dynamic random access memory (DRAM).

[0112] The database involved in each embodiment provided in this application may include at least one of a relational database and a non-relational database. The non-relational database may include a distributed database based on blockchain, etc., but is not limited thereto. The processor involved in each embodiment provided in this application may be a general-purpose processor, a central processing unit, a graphics processor, a digital signal processor, a programmable logic device, a data processing logic device based on quantum computing, etc., but is not limited thereto.

[0113] The technical features of the above embodiments may be combined arbitrarily. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0114] This article uses specific examples to illustrate the principles and implementation methods of this application. The description of the above embodiments is only used to help understand the method and core ideas of this application. At the same time, for those skilled in the art, according to the ideas of this application, there will be changes in the specific implementation methods and application scope. In summary, the content of this specification should not be understood as limiting this application.

Claims

1. A method for positioning the cutting center of femtosecond laser refractive surgery, characterized in that: include: Acquire an eye image of a patient in a sitting position under a set light illumination, and determine a first iris image and a first relative position; the first relative position is the relative position of a first pupil center and a first visual axis center; The first pupil center is the pupil center of the patient to be operated on when the patient is sitting and looking at the fixation light; the first visual axis center is the coaxial reflection point in the eye image of the patient in the sitting position; Acquire an eye image of a patient in a lying position to be operated on under a set light illumination; Determining a second iris image and a second pupil center of the patient to be operated on according to the lying eye image; determining a first eyeball rotation angle according to the first iris image and the second iris image; According to the first pupil center, the first relative position and the first eyeball rotation angle, a second visual axis center of the patient to be operated on is calculated, and a second relative position between the second visual axis center and the second pupil center is calculated; the second visual axis center is the visual axis center of the patient to be operated on in a lying position; performing negative pressure suction according to the second relative position guidance; Aligning the center of the negative pressure suction ring with the center of the second visual axis, and determining whether the center of the negative pressure suction ring is aligned with the center of the second visual axis; If yes, a prompt is given to start negative pressure suction, and a third iris image of the patient to be operated on is obtained under the set light illumination, and a third pupil center is determined; According to the first pupil center, the first relative position and the second eyeball rotation angle, the third visual axis center of the patient to be operated on is calculated, and the third relative position between the third visual axis center and the third pupil center is calculated; the second eyeball rotation angle is determined according to the first iris image and the third iris image; the third visual axis center is the visual axis center of the patient to be operated on during the negative pressure suction process; Determining whether the center of the negative pressure suction ring is aligned with the center of the third visual axis; If so, the third visual axis center is used as the cutting center, and the astigmatism axis of the femtosecond laser equipment cutting model is adjusted according to the second eyeball rotation angle, prompting to start laser scanning.

2. The method for positioning the cutting center of femtosecond laser refractive surgery according to claim 1, characterized in that: If not, perform vacuum suction again.

3. The method for positioning the cutting center of femtosecond laser refractive surgery according to claim 1, characterized in that: If not, adjust the center of the cutting model of the femtosecond laser device to the center of the third visual axis, adjust the astigmatism axis of the cutting model according to the second eye rotation angle, and prompt to start laser scanning.

4. The method for positioning the cutting center of femtosecond laser refractive surgery according to claim 1, characterized in that: Acquiring an eye image of a patient in a sitting position to be operated under a set light illumination, and determining a first iris image and a relative position, specifically includes: Acquire an eye image of a patient in a sitting position to be operated on under a set light illumination; Determining a first pupil diameter, a first iris image, a first pupil center, and a first visual axis center of the patient to be operated on according to the sitting eye image; A first relative position is determined based on the first pupil center and the first visual axis center.

5. The method for positioning the cutting center of femtosecond laser refractive surgery according to claim 1, characterized in that: Obtaining an eye image of a patient in a lying position under a set light intensity, specifically including: The patient to be operated on looks at the fixation light while lying in preparation for the operation; Adjusting the light brightness to a set light brightness so that the pupil center of the patient to be operated on coincides with the first pupil center; The lying eye image is captured.

6. The method for positioning the cutting center of femtosecond laser refractive surgery according to claim 1, characterized in that: Determining a first eyeball rotation angle according to the first iris image and the second iris image specifically includes: Determine the positions of an inner circle and an outer circle in the first iris image and the second iris image respectively, and obtain a processed first iris image and a processed second iris image; the inner circle is a boundary between the iris and the pupil; the outer circle is a boundary between the iris and the sclera; performing normalization processing on the processed first iris image and the processed second iris image respectively to obtain a normalized first iris image and a normalized second iris image; performing image enhancement on the normalized first iris image and the normalized second iris image respectively to obtain an enhanced first iris image and an enhanced second iris image; Determining a first iris feature point angle according to the enhanced first iris image; Determining a second iris feature point angle according to the enhanced second iris image; The first eyeball rotation angle is determined according to the first iris feature point angle and the second iris feature point angle.

7. The method for positioning the cutting center of femtosecond laser refractive surgery according to claim 6, characterized in that: Determining the first eyeball rotation angle according to the first iris feature point angle and the second iris feature point angle specifically includes: The first eyeball rotation angle is determined using the formula λ1=α-β1, wherein λ1 is the first eyeball rotation angle; α is the first iris feature point angle; and β1 is the second iris feature point angle.

8. The method for positioning the cutting center of femtosecond laser refractive surgery according to claim 1, characterized in that: Determining a second eyeball rotation angle according to the first iris image and the third iris image specifically includes: Determine the positions of an inner circle and an outer circle in the first iris image and the third iris image, respectively, to obtain a processed first iris image and a processed third iris image; the inner circle is a boundary between the iris and the pupil; the outer circle is a boundary between the iris and the sclera; performing normalization processing on the processed first iris image and the processed third iris image respectively to obtain a normalized first iris image and a normalized third iris image; performing image enhancement on the normalized first iris image and the normalized third iris image respectively to obtain an enhanced first iris image and an enhanced third iris image; Determining a first iris feature point angle according to the enhanced first iris image; Determining a third iris feature point angle according to the enhanced third iris image; The second eyeball rotation angle is determined according to the first iris feature point angle and the third iris feature point angle.

9. The method for positioning the cutting center of femtosecond laser refractive surgery according to claim 8, characterized in that: Determining the second eyeball rotation angle according to the first iris feature point angle and the third iris feature point angle specifically includes: The second eyeball rotation angle is determined using the formula λ2=α-β2, wherein λ2 is the second eyeball rotation angle; α is the first iris feature point angle; and β2 is the third iris feature point angle.

10. A computer device comprising: A memory, a processor, and a computer program stored in the memory and executable on the processor, wherein the processor executes the computer program to implement the femtosecond laser refractive surgery cutting center positioning method described in any one of claims 1-9.

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