Soothing, anti-wrinkle and moisturizing lotion and preparation method thereof

Abstract

The invention belongs to the technical field of cosmetics, and particularly discloses a soothing anti-wrinkle moisturizing lotion and a preparation method thereof, the soothing anti-wrinkle moisturizing lotion comprises the following components by mass: 0.02-0.12% of a chelating agent, 4-8% of a humectant, 0.2-0.6% of a thickener, 0.5-2% of pitaya stem polysaccharide, 5-15% of pitaya seed oil, 0.3-1% of tocopheryl acetate, 1-3% of an emulsifier, 0.02-0.1% of rose essential oil, 5-10% of a pitaya peel extract, 0.3-0.5% of p-hydroxyacetophenone, 0.5-1% of 1, 2-propylene glycol, and the balance of water. The cleaning agent comprises the following components in percentage by weight: 0.02-0.1% of 1, 2-hexanediol, 0.02-0.1% of pH According to the soothing, anti-wrinkle and moisturizing lotion, the dragon fruit stem polysaccharide, the dragon fruit seed oil and the dragon fruit peel extracting solution which are naturally sourced are added, and the soothing, anti-wrinkle and moisturizing lotion is green and natural in component source, free of essence, pigment and preservative, safe, effective, mild and non-irritant.

Description

Technical Field

[0001] The invention relates to the technical field of cosmetics, and in particular to a soothing, anti-wrinkle and moisturizing emulsion and a preparation method thereof. Background Art

[0002] As the world promotes sustainable development in all fields, sustainable consumption in the cosmetics field is also expanding. The sustainable development trend of the cosmetics market to coexist with the environmental ecology is becoming a core topic. More and more consumers are beginning to screen and choose skin care products with natural ingredients, green sources, and environmental friendliness.

[0003] Dragon fruit is not only sweet, but also has high nutritional value. It combines the advantages of fruit, flower buds, vegetables and medicine. It is not only nutritious and unique in function, but also has few diseases and pests, and can grow normally without using any pesticides. Therefore, dragon fruit is a green, environmentally friendly fruit and a health food with certain therapeutic effects. Due to the huge dragon fruit industry chain in my country, many by-products are produced and have not been reasonably utilized. Most dragon fruit processing plants only use the dragon fruit pulp, while the dragon fruit peel, dragon fruit seeds and dragon fruit stems can only be discarded or simply processed into feed.

[0004] In view of this, this application is filed. Summary of the invention

[0005] The invention provides a soothing anti-wrinkle moisturizing lotion and a preparation method thereof. The soothing anti-wrinkle moisturizing lotion of the invention is added with natural pitaya stem polysaccharide, pitaya seed oil and pitaya peel extract, the ingredients are green and natural, and do not contain essence, pigment and preservative, so as to be truly safe, effective, mild and non-irritating.

[0006] The present invention solves the technical problem by adopting the following technical solutions: A soothing, anti-wrinkle and moisturizing lotion comprises the following components in percentage by mass: 0.02-0.12% of a chelating agent, 4-8% of a moisturizing agent, 0.2-0.6% of a thickener, 0.5-2% of pitaya stem polysaccharide, 5-15% of pitaya seed oil, 0.3-1% of tocopherol acetate, 1-3% of an emulsifier, 0.02-0.1% of rose essential oil, 5-10% of pitaya peel extract, 0.3-0.5% of p-hydroxyacetophenone, 0.5-1% of 1,2-hexanediol, 0.02-0.1% of a pH regulator, and the balance of deionized water.

[0007] The pitaya peel contains a large amount of betalain, rich carbohydrates, proteins, anthocyanins, vitamins C, B1, B2, B3, calcium, phosphorus, iron and other minerals, and is rich in nutrition; pitaya seeds contain rich calcium, phosphorus, iron and other minerals and various enzymes, albumin, arachidonic acid, flavonoids, and flavonoids; pitaya stems contain a variety of trace elements necessary for the human body, as well as a large amount of plant polysaccharides, vitamins and various plant sterols. In the present invention, after a series of purification and extraction operations, pitaya stem polysaccharides, pitaya seed oil, and pitaya peel extract are added to the emulsion system. Under the synergistic effect of the three, the soothing and anti-wrinkle effect can be achieved.

[0008] The soothing, anti-wrinkle and moisturizing lotion of the present invention is added with naturally-derived pitaya stem polysaccharide, pitaya seed oil and pitaya peel extract, and the ingredients are green and natural, and do not contain flavors, pigments or preservatives, so it is truly safe, effective, mild and non-irritating.

[0009] The soothing, anti-wrinkle and moisturizing lotion of the present invention is added with pitaya stem polysaccharides extracted by ultrasound-assisted low eutectic solvent method. The organic and inorganic solvents used in traditional polysaccharide extraction generally have long extraction time, large solvent consumption, low extraction efficiency and certain pollution problems. As an emerging green solvent, low eutectic solvent has a variety of solvent properties that traditional organic solvents do not have. Pitaya seed oil is produced by subcritical extraction process. Compared with the traditional "pre-pressing-leaching" processing method, although the oil extraction efficiency reaches more than 95%, the material has been treated at high temperature for a long time and has poor quality. It requires a complex refining process, and the loss of heat-sensitive functional ingredients is large. The effective amino acids of the protein are significantly damaged, which seriously affects its comprehensive utilization value. The diffusion performance of solvent molecules in the subcritical state is enhanced, the mass transfer rate is accelerated, and the solubility capacity is significantly improved. It has the advantages of low desolvation temperature, high extraction efficiency, and greatly reduced production costs. The pitaya peel extract is produced by CO 2 It is obtained by supercritical extraction, enzymatic hydrolysis and nanofiltration separation. The whole extraction temperature does not exceed 60 degrees, which can not affect the activity of high temperature-resistant substances such as anthocyanins and vitamin C, while retaining components with a relative molecular weight of less than 1000Da. Extracts within this relative molecular weight range are more easily absorbed by the skin.

[0010] As a preferred embodiment of the present invention, the preparation method of the pitaya stem polysaccharide is: (1) taking fresh pitaya stems, removing thorns and extracting the middle fiber bundles, cutting into sections, washing with deionized water, freeze-drying, and crushing to obtain pitaya stem freeze-dried powder; (2) adding choline chloride and oxalic acid dihydrate into water to prepare a eutectic aqueous solution with a water content of 60-70%; the molar ratio of choline chloride to oxalic acid dihydrate is 2:(0.8-1.2); (3) The pitaya stem freeze-dried powder and the low eutectic aqueous solution were mixed evenly at a solid-liquid ratio of 1 g: (20-30) mL and placed in a microwave extractor. The mixture was extracted at a power of 400-600 W and a temperature of 70-80 ° C for 3-6 min. The mixture was filtered to obtain a crude extract of pitaya stem polysaccharide. (4) Add 3.5-4.5 times the volume of ethanol solution to the crude extract of pitaya stem polysaccharide, let it stand for 100-150 minutes, centrifuge, collect the precipitate, wash it with ethanol solution for 3-4 times, centrifuge, collect the precipitate, and obtain pitaya stem polysaccharide; the volume concentration of the ethanol solution is 85-98%.

[0011] As a preferred embodiment of the present invention, the preparation method of the pitaya seed oil is: (1) Soaking pitaya seeds in physiological saline at 35-50° C. for 10-18 h, drying, placing in a microwave extractor, heating at 400-600 W and 110-130° C. for 10-20 min, shelling to obtain shelled pitaya seeds, and crushing to obtain shelled pitaya seed powder; (2) The shelled pitaya seed powder and n-butane were added into a subcritical extraction device at a solid-liquid ratio of 1 g: (8-12) mL. The extraction was performed at 35-40 °C for 35-40 min. The pressure was reduced to 0.01-0.03 MPa and centrifuged to obtain pitaya seed oil.

[0012] As a preferred embodiment of the present invention, the preparation method of the pitaya peel extract is: (1) drying the pitaya peel until the moisture content is less than 1%, crushing the pitaya peel to obtain pitaya peel powder, and putting the pitaya peel powder into a supercritical extraction kettle for extraction to obtain a pitaya peel extract; (2) Add the complex enzyme to the pitaya peel extract, perform enzymolysis at 45-55°C for 2-6 hours, and filter with a nanofiltration membrane with a molecular weight cutoff of 1000 Da to obtain the pitaya peel extract.

[0013] As a preferred embodiment of the present invention, the extraction pressure is 15-20 MPa, the extraction temperature is 50-60°C, the separation kettle I pressure is 10-15 MPa, the temperature is 50-60°C, the separation kettle II pressure is 5-8 MPa, the temperature is 40-50°C; CO 2 The flow rate is 80~100kg / h and the extraction time is 1~3h.

[0014] As a preferred embodiment of the present invention, the complex enzyme includes endopeptidase, cellulase, hemicellulase and glucoamylase, and the mass ratio of the endopeptidase, cellulase, hemicellulase, glucoamylase and pitaya peel extract is (0.001~0.005):(0.001~0.005):(0.001~0.005):(0.001~0.005):1.

[0015] As a preferred embodiment of the present invention, the humectant includes at least one of glycerin, butylene glycol, sorbitol, xylitol, glyceryl polyether-26, hydroxyethyl urea, erythritol, and dipropylene glycol.

[0016] As a preferred embodiment of the present invention, the thickener includes xanthan gum, sodium alginate, carrageenan, carrageenan, guar gum, acrylic acid (ester) / C 10～30 At least one of an alkyl acrylate cross-linked polymer.

[0017] As a preferred embodiment of the present invention, the emulsifier includes at least one of cetearyl olivate / sorbitan olivate (trade name OLIVEM 1000), hydrogenated lecithin / phytosterols, hydrogenated lysolecithin, and steareth-2 / steareth-21.

[0018] Wherein, the chelating agent is EDTA-2Na.

[0019] The pH regulator is sodium hydroxide.

[0020] The present invention also provides a method for preparing the soothing, anti-wrinkle and moisturizing emulsion, comprising the following steps: Mixing pitaya seed oil, tocopherol acetate and emulsifier at 80-90° C. to obtain an oil phase; The chelating agent, humectant and thickener are mixed evenly, and then pitaya stem polysaccharide and deionized water are added, and the mixture is heated to 75-85° C. with stirring, and then the oil phase is added, and the mixture is stirred for 2-8 minutes and then homogenized. When the temperature is cooled to 40-45° C., rose essential oil, pitaya peel extract, p-hydroxyacetophenone, 1,2-hexanediol and pH adjuster are added, and the mixture is stirred evenly to obtain a soothing, anti-wrinkle and moisturizing lotion.

[0021] The beneficial effects of the present invention are as follows: (1) The soothing and anti-wrinkle moisturizing lotion of the present invention adds pitaya stem polysaccharide, pitaya seed oil and pitaya peel extract from natural sources, and the ingredients are green and natural, and do not contain flavors, pigments and preservatives, so that the lotion is truly safe, effective, mild and non-irritating. (2) The present invention adds pitaya stem polysaccharide, pitaya seed oil and pitaya peel extract to the lotion system, and under the synergistic effect of the three, the soothing and anti-wrinkle effect can be achieved. The soothing and anti-wrinkle moisturizing lotion contains rich anthocyanins, phytosterols, flavonoids, flavonoids and water-soluble vitamins, and these substances can play an antioxidant and anti-wrinkle role. DETAILED DESCRIPTION

[0022] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be described clearly and completely below. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0023] In the present invention, the technical features described in an open manner include closed technical solutions composed of the listed features, and also include open technical solutions containing the listed features.

[0024] In the present invention, when it comes to numerical ranges, unless otherwise specified, the above numerical ranges are deemed to be continuous and include the minimum and maximum values ​​of the range, as well as each value between such minimum and maximum values. Further, when a range refers to an integer, each integer between the minimum and maximum values ​​of the range is included. In addition, when multiple ranges are provided to describe features or characteristics, the ranges can be merged. In other words, unless otherwise specified, all ranges disclosed herein should be understood to include any and all subranges included therein.

[0025] In the present invention, there is no particular limitation on the specific dispersion and stirring treatment methods.

[0026] The reagents or instruments used in the present invention without indicating the manufacturer are all conventional products that can be obtained commercially. The raw materials used in the comparative examples and the raw materials used in the parallel experiments of the embodiments are the same commercially available products unless otherwise specified.

[0027] The preparation method of the pitaya stem polysaccharide used in the embodiments and comparative examples is as follows: (1) Take fresh pitaya stems, remove the thorns and extract the middle fiber bundles, cut into small segments of 3 to 5 mm, wash with deionized water, put into a vacuum freeze dryer for freeze drying, and crush to obtain pitaya stem freeze-dried powder; (2) adding choline chloride and oxalic acid dihydrate into water, shaking well, and letting stand to prepare a uniform, transparent eutectic aqueous solution with a water content of 67%; the molar ratio of choline chloride to oxalic acid dihydrate is 2:1; (3) The pitaya stem freeze-dried powder and the low eutectic aqueous solution were mixed evenly at a solid-liquid ratio of 1 g: 24 mL and placed in a microwave extractor for extraction at 500 W power and 75 ° C for 4 min. After the extraction was completed, the supernatant was aspirated and filtered with a 0.45 nm filter membrane to obtain a crude extract of pitaya stem polysaccharide; (4) Add 4 times the volume of ethanol solution to the crude extract of pitaya stem polysaccharide, let it stand for 120 minutes, centrifuge at 7000 rpm for 20 minutes, collect the precipitate, wash it three times with ethanol solution, centrifuge at 7000 rpm for 20 minutes, collect the precipitate, and obtain pitaya stem polysaccharide; the volume concentration of the ethanol solution is 90%.

[0028] Wherein, the preparation method of the pitaya seed oil used in the embodiment and the comparative example is: (1) separating pitaya seeds from pitaya pulp, soaking the pitaya seeds in physiological saline at 45°C for 12 hours, drying, placing the pitaya seeds in a microwave extractor, heating at 500W power and 120°C for 15 minutes, shelling the pitaya seeds to obtain shelled pitaya seeds, and crushing the seeds in a low-temperature press to obtain shelled pitaya seed powder; (2) Shelled pitaya seed powder and n-butane were added into a subcritical extraction device at a solid-liquid ratio of 1 g: (8-12) mL. The extraction was carried out at 38 °C for 38 min. The pressure was reduced to 0.02 MPa and the mixture was centrifuged at 7000 rpm for 6 min to obtain pitaya seed oil.

[0029] The preparation method of the pitaya peel extract used in the embodiments and comparative examples is as follows: (1) After the dragon fruit peel is cleaned, it is naturally dried in the shade and then placed in a vacuum drying oven for drying. When the water content is less than 1%, it is placed in a grinder and pulverized to obtain dragon fruit peel powder. The dragon fruit peel powder is placed in a supercritical extraction kettle, and the extraction pressure is selected to be 18 MPa and the extraction temperature is 55°C; the pressure of separation kettle I is 12 MPa and the temperature is 55°C, and the pressure of separation kettle II is 7 MPa and the temperature is 45°C; CO 2 The flow rate is 90 kg / h, the extraction time is 2 h, and the pitaya peel extract is obtained; (2) Add the complex enzyme to the pitaya peel extract, perform enzymolysis at 50°C for 4 h, and filter using a rolled nanofiltration membrane with a molecular weight cutoff of 1000 Da to obtain the pitaya peel extract.

[0030] The complex enzyme comprises endopeptidase, cellulase, hemicellulase and glucoamylase, and the mass ratio of the endopeptidase, cellulase, hemicellulase, glucoamylase and pitaya peel extract is 0.003:0.003:0.003:0.003:1.

[0031] Example 1 A soothing, anti-wrinkle and moisturizing lotion comprising the following components in percentage by mass: 0.2% acrylic acid (ester) / C 10～30Alkyl acrylate crosspolymer (Carbopol Ultrez 21, the same below), 5% glycerin, 1% butylene glycol, 2% glyceryl polyether-26, 0.1% disodium EDTA, 0.5% pitaya stem polysaccharide, 6% pitaya seed oil, 0.3% tocopheryl acetate, 1% cetearyl olivate / sorbitan olivate, 1% glyceryl stearate, 0.1% rose essential oil, 10% pitaya peel extract, 0.5% p-hydroxyacetophenone, 0.5% 1,2-hexanediol, 0.04% sodium hydroxide, and the balance deionized water.

[0032] The method for preparing the soothing, anti-wrinkle and moisturizing emulsion comprises the following steps: Mix pitaya seed oil, tocopherol acetate, cetearyl olivate / sorbitan olivate, and glyceryl stearate at 85° C. to obtain an oil phase; Disodium EDTA, glycerin, butylene glycol, glyceryl polyether-26, acrylic acid (esters) / C 10～30 The alkyl acrylate cross-linked polymer is evenly mixed, and pitaya stem polysaccharide and deionized water are added. After stirring and heating to 80° C., the oil phase is added and stirred for 5 minutes for homogenization. When the temperature is cooled to 45° C., rose essential oil, pitaya peel extract, p-hydroxyacetophenone, 1,2-hexanediol and sodium hydroxide are added and stirred evenly to obtain a soothing anti-wrinkle moisturizing lotion.

[0033] Example 2 The difference between Example 2 and Example 1 is that the amount of raw materials is different, and the other aspects are the same.

[0034] A soothing, anti-wrinkle and moisturizing lotion comprising the following components in percentage by mass: 0.2% acrylic acid (ester) / C 10～30 Alkyl acrylate crosspolymer, 5% glycerin, 1% butylene glycol, 2% glyceryl polyether-26, 0.1% disodium EDTA, 2% pitaya stem polysaccharide, 6% pitaya seed oil, 0.3% tocopheryl acetate, 1% cetearyl olivate / sorbitan olivate, 1% glyceryl stearate, 0.1% rose essential oil, 5% pitaya peel extract, 0.5% p-hydroxyacetophenone, 0.5% 1,2-hexanediol, 0.04% sodium hydroxide, balance deionized water.

[0035] Example 3 The difference between Example 3 and Example 1 is that the amount of raw materials is different, and everything else is the same.

[0036] A soothing, anti-wrinkle and moisturizing lotion comprising the following components in percentage by mass: 0.2% acrylic acid (ester) / C 10～30Alkyl acrylate crosspolymer, 5% glycerin, 1% butylene glycol, 2% glyceryl polyether-26, 0.1% disodium EDTA, 2% pitaya stem polysaccharide, 9% pitaya seed oil, 0.3% tocopheryl acetate, 2% cetearyl olivate / sorbitan olivate, 1% glyceryl stearate, 0.1% rose essential oil, 8% pitaya peel extract, 0.5% p-hydroxyacetophenone, 0.5% 1,2-hexanediol, 0.04% sodium hydroxide, balance deionized water.

[0037] Comparative Example 1 The difference between Comparative Example 1 and Example 2 is that Comparative Example 1 does not contain pitaya stem polysaccharide.

[0038] A soothing, anti-wrinkle and moisturizing lotion comprising the following components in percentage by mass: 0.2% acrylic acid (ester) / C 10～30 Alkyl acrylate crosspolymer, 5% glycerin, 1% butylene glycol, 2% glyceryl polyether-26, 0.1% disodium EDTA, 6% pitaya seed oil, 0.3% tocopheryl acetate, 1% cetearyl olivate / sorbitan olivate, 1% glyceryl stearate, 0.1% rose essential oil, 5% pitaya peel extract, 0.5% p-hydroxyacetophenone, 0.5% 1,2-hexanediol, 0.04% sodium hydroxide, balance deionized water.

[0039] Comparative Example 2 The difference between Comparative Example 2 and Example 2 is that Comparative Example 2 does not contain pitaya seed oil.

[0040] A soothing, anti-wrinkle and moisturizing lotion comprising the following components in percentage by mass: 0.2% acrylic acid (ester) / C 10～30 Alkyl acrylate crosspolymer, 5% glycerin, 1% butylene glycol, 2% glyceryl polyether-26, 0.1% disodium EDTA, 2% pitaya stem polysaccharide, 0.3% tocopheryl acetate, 1% cetearyl olivate / sorbitan olivate, 1% glyceryl stearate, 0.1% rose essential oil, 5% pitaya peel extract, 0.5% p-hydroxyacetophenone, 0.5% 1,2-hexanediol, 0.04% sodium hydroxide, balance deionized water.

[0041] Comparative Example 3 The difference between Comparative Example 3 and Example 2 is that Comparative Example 3 does not contain pitaya peel extract.

[0042] A soothing, anti-wrinkle and moisturizing lotion comprising the following components in percentage by mass: 0.2% acrylic acid (ester) / C 10～30Alkyl acrylate crosspolymer, 5% glycerin, 1% butylene glycol, 2% glyceryl polyether-26, 0.1% disodium EDTA, 2% pitaya stem polysaccharide, 6% pitaya seed oil, 0.3% tocopheryl acetate, 1% cetearyl olive oil / sorbitan olive oil ester, 1% glyceryl stearate, 0.1% rose essential oil, 0.5% p-hydroxyacetophenone, 0.5% 1,2-hexanediol, 0.04% sodium hydroxide, balance deionized water.

[0043] Comparative Example 4 The difference between Comparative Example 4 and Example 2 is that Comparative Example 4 does not contain pitaya stem polysaccharide (but the total amount of pitaya stem polysaccharide, pitaya seed oil, and pitaya peel extract is the same as that in Example 2).

[0044] A soothing, anti-wrinkle and moisturizing lotion comprising the following components in percentage by mass: 0.2% acrylic acid (ester) / C 10～30 Alkyl acrylate crosspolymer, 5% glycerin, 1% butylene glycol, 2% glyceryl polyether-26, 0.1% disodium EDTA, 7% pitaya seed oil, 0.3% tocopheryl acetate, 1% cetearyl olivate / sorbitan olivate, 1% glyceryl stearate, 0.1% rose essential oil, 6% pitaya peel extract, 0.5% p-hydroxyacetophenone, 0.5% 1,2-hexanediol, 0.04% sodium hydroxide, the balance is deionized water.

[0045] Comparative Example 5 The difference between Comparative Example 5 and Example 2 is that Comparative Example 5 does not contain pitaya seed oil (but the total amount of pitaya stem polysaccharide, pitaya seed oil, and pitaya peel extract is the same as that in Example 2).

[0046] A soothing, anti-wrinkle and moisturizing lotion comprising the following components in percentage by mass: 0.2% acrylic acid (ester) / C 10～30 Alkyl acrylate crosspolymer, 5% glycerin, 1% butylene glycol, 2% glyceryl polyether-26, 0.1% disodium EDTA, 5% pitaya stem polysaccharide, 0.3% tocopheryl acetate, 1% cetearyl olivate / sorbitan olivate, 1% glyceryl stearate, 0.1% rose essential oil, 8% pitaya peel extract, 0.5% p-hydroxyacetophenone, 0.5% 1,2-hexanediol, 0.04% sodium hydroxide, the balance is deionized water.

[0047] Comparative Example 6 The difference between Comparative Example 6 and Example 2 is that Comparative Example 6 does not contain pitaya peel extract (but the total amount of pitaya stem polysaccharide, pitaya seed oil, and pitaya peel extract is the same as that in Example 2).

[0048] A soothing, anti-wrinkle and moisturizing lotion comprising the following components in percentage by mass: 0.2% acrylic acid (ester) / C10～30 Alkyl acrylate crosspolymer, 5% glycerin, 1% butylene glycol, 2% glyceryl polyether-26, 0.1% disodium EDTA, 4.5 fruit stem polysaccharides, 8.5% pitaya seed oil, 0.3% tocopheryl acetate, 1% cetearyl olive oil / sorbitan olive oil ester, 1% glyceryl stearate, 0.1% rose essential oil, 0.5% p-hydroxyacetophenone, 0.5% 1,2-hexanediol, 0.04% sodium hydroxide, the balance is deionized water.

[0049] Comparative Example 7 The difference between Comparative Example 7 and Example 2 is that Comparative Example 7 uses an equal amount of Tremella polysaccharide to replace pitaya stem polysaccharide.

[0050] A soothing, anti-wrinkle and moisturizing lotion comprising the following components in percentage by mass: 0.2% acrylic acid (ester) / C 10～30 Alkyl acrylate crosspolymer, 5% glycerin, 1% butylene glycol, 2% glyceryl polyether-26, 0.1% disodium EDTA, 2% tremella polysaccharide, 6% pitaya seed oil, 0.3% tocopheryl acetate, 1% cetearyl olivate / sorbitan olivate, 1% glyceryl stearate, 0.1% rose essential oil, 5% pitaya peel extract, 0.5% p-hydroxyacetophenone, 0.5% 1,2-hexanediol, 0.04% sodium hydroxide, balance deionized water.

[0051] Comparative Example 8 The difference between Comparative Example 8 and Example 2 is that Comparative Example 8 uses an equal amount of grape seed oil to replace the pitaya seed oil.

[0052] A soothing, anti-wrinkle and moisturizing lotion comprising the following components in percentage by mass: 0.2% acrylic acid (ester) / C 10～30 Alkyl acrylate crosspolymer, 5% glycerin, 1% butylene glycol, 2% glyceryl polyether-26, 0.1% disodium EDTA, 2% pitaya stem polysaccharide, 6% grape seed oil, 0.3% tocopheryl acetate, 1% cetearyl olivate / sorbitan olivate, 1% glyceryl stearate, 0.1% rose essential oil, 5% pitaya peel extract, 0.5% p-hydroxyacetophenone, 0.5% 1,2-hexanediol, 0.04% sodium hydroxide, the balance is deionized water.

[0053] Test example: 1. Comparative test of skin moisture content: Test subjects: 110 volunteers (male to female ratio of 1:1), aged 20 to 35 years old, healthy. The 110 volunteers were randomly divided into 11 groups, 10 people in each group, and the products of the test examples and comparative examples were used in the morning and evening (3 drops each time), and the test area was a 2cm×3cm rectangular area selected from the same part of the forehead.

[0054] Test conditions: 1) Indoor environment; 2) No strong sunlight or direct light; 3) Ambient temperature 25±2℃, ambient humidity 40%~60%.

[0055] The following tests were conducted for 0.5 h: the skin moisture tester MDD4-Corneometer CM825 was used for testing, and the average was taken as the skin moisture content before use (recorded as A0); the volunteers then washed their faces with clean water, and 0.5 h later, the skin moisture tester MDD4-Corneometer CM825 was used for testing, and the average was taken as the skin moisture content after 0.5 h of use (recorded as A1), and the skin moisture content change rate was calculated = [(A1-A0) / A0] 100%.

[0056] After one month of use, the following tests were performed: The test area was measured using the Reviscometer RV600 (elastic fiber tissue test probe) of the German CK skin elasticity tester MPA580, and the skin elasticity index R of the test area was recorded. 2 , R 5 , R 7 The average value was taken as the initial data of the volunteers (the negative pressure was constant at 450mbar during the test). Used continuously for one month (no other skin care products were used during this period). Measured the test area again and recorded the skin elasticity index R of the test area. 2 , R 5 , R 7 The average of the values ​​was taken as the final data of the volunteers (the negative pressure was constant at 450 mbar during the test).

[0057] R before test 2 Denoted as R 2前 , R2 after the test is recorded as R 2后 , R 2 Rate of change = [(R 2后 -R 2前 ) / R 2前 】 100%.

[0058] R before test 5 Denoted as R 5前 , R after testing 5 Denoted as R 5后 , R 5 Rate of change = [(R 5后 -R 5前 ) / R 5前 】 100%.

[0059] R before test 7 Denoted as R7前 , R after testing 7 Denoted as R 7后 , R 7 Rate of change = [(R 7后 -R 7前 ) / R 7前 】 100%.

[0060] Note: Skin elasticity index R 2 , R 5 , R 7 The closer it is to 1, the better the skin's elasticity.

[0061] R 2 =U a / U f ; R 5 =U r / U e ; R 7 =U r / U f ; U f ——Maximum stretch of skin; U e ——After constant negative pressure is applied to the skin, the amount of skin stretching in 0.1 seconds, and the amount of stretching of the positioning elastic part; U r ——After the negative pressure is removed, the skin will quickly return to its original state, which is also divided into the elastic part value U r , that is, the recovery value and viscoelastic part value of the skin, or the plastic part value, 0.1 seconds after the negative pressure is removed; U a ——The recovery value of the skin from the time when negative pressure is cancelled to the time when negative pressure is applied to the skin surface again during the next continuous test.

[0062] Table 1

[0063] As can be seen from Table 1, the emulsion of the present invention has excellent soothing and anti-wrinkle effects and has broad application prospects. The pitaya stem polysaccharide, pitaya seed oil and pitaya peel extract have significant synergistic effects.

[0064] Finally, it should be noted that the above embodiments are intended to illustrate the technical solution of the present invention rather than to limit the scope of protection of the present invention. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solution of the present invention may be modified or replaced by equivalents without departing from the essence and scope of the technical solution of the present invention.

Claims

1. A soothing anti-wrinkle moisturizing lotion, characterized in that: The invention comprises the following components in percentage by weight: 0.02-0.12% of a chelating agent, 4-8% of a moisturizing agent, 0.2-0.6% of a thickener, 0.5-2% of pitaya stem polysaccharide, 5-15% of pitaya seed oil, 0.3-1% of tocopherol acetate, 1-3% of an emulsifier, 0.02-0.1% of rose essential oil, 5-10% of pitaya peel extract, 0.3-0.5% of p-hydroxyacetophenone, 0.5-1% of 1,2-hexanediol, 0.02-0.1% of a pH regulator, and the balance of deionized water.

2. The soothing anti-wrinkle moisturizing lotion according to claim 1, characterized in that: The preparation method of the pitaya stem polysaccharide is: (1) taking fresh pitaya stems, removing thorns and extracting the middle fiber bundles, cutting into sections, washing with deionized water, freeze-drying, and crushing to obtain pitaya stem freeze-dried powder; (2) adding choline chloride and oxalic acid dihydrate into water to prepare a eutectic aqueous solution with a water content of 60-70%; the molar ratio of choline chloride to oxalic acid dihydrate is 2:(0.8-1.2); (3) The pitaya stem freeze-dried powder and the low eutectic aqueous solution were mixed evenly at a solid-liquid ratio of 1 g: (20-30) mL and placed in a microwave extractor. The mixture was extracted at a power of 400-600 W and a temperature of 70-80 ° C for 3-6 min. The mixture was filtered to obtain a crude extract of pitaya stem polysaccharide. (4) Add 3.5-4.5 times the volume of ethanol solution to the crude extract of pitaya stem polysaccharide, let it stand for 100-150 minutes, centrifuge, collect the precipitate, wash it with ethanol solution for 3-4 times, centrifuge, collect the precipitate, and obtain pitaya stem polysaccharide; The volume concentration of the ethanol solution is 85-98%.

3. The soothing anti-wrinkle moisturizing lotion according to claim 1, characterized in that: The preparation method of the pitaya seed oil is: (1) Soaking pitaya seeds in physiological saline at 35-50° C. for 10-18 h, drying, placing in a microwave extractor, heating at 400-600 W and 110-130° C. for 10-20 min, shelling to obtain shelled pitaya seeds, and crushing to obtain shelled pitaya seed powder; (2) The shelled pitaya seed powder and n-butane were added into a subcritical extraction device at a solid-liquid ratio of 1 g: (8-12) mL. The extraction was performed at 35-40 °C for 35-40 min. The pressure was reduced to 0.01-0.03 MPa and centrifuged to obtain pitaya seed oil.

4. The soothing anti-wrinkle moisturizing lotion according to claim 1, characterized in that: The preparation method of the pitaya peel extract is: (1) drying the pitaya peel until the moisture content is less than 1%, crushing the pitaya peel to obtain pitaya peel powder, and putting the pitaya peel powder into a supercritical extraction kettle for extraction to obtain a pitaya peel extract; (2) Add the complex enzyme to the pitaya peel extract, perform enzymolysis at 45-55°C for 2-6 hours, and filter with a nanofiltration membrane with a molecular weight cutoff of 1000 Da to obtain the pitaya peel extract.

5. The soothing anti-wrinkle moisturizing lotion according to claim 4, characterized in that: The extraction pressure is 15-20Mpa, the extraction temperature is 50-60°C, the pressure of separation kettle I is 10-15Mpa, the temperature is 50-60°C, the pressure of separation kettle II is 5-8Mpa, and the temperature is 40-50°C; the CO2 flow rate is 80-100kg / h, and the extraction time is 1-3h.

6. The soothing anti-wrinkle moisturizing lotion according to claim 4, characterized in that: The complex enzyme comprises endopeptidase, cellulase, hemicellulase and glucoamylase, and the mass ratio of the endopeptidase, cellulase, hemicellulase, glucoamylase and pitaya peel extract is (0.001-0.005):(0.001-0.005):(0.001-0.005):(0.001-0.005):

1.

7. The soothing anti-wrinkle moisturizing lotion according to claim 1, characterized in that: The moisturizing agent includes at least one of glycerin, butylene glycol, sorbitol, xylitol, glyceryl polyether-26, hydroxyethyl urea, erythritol, and dipropylene glycol.

8. The soothing anti-wrinkle moisturizing lotion according to claim 1, characterized in that: The thickener includes xanthan gum, sodium alginate, carrageenan, carrageenan, guar gum, acrylic acid (ester) / C 10～30 At least one of an alkyl acrylate cross-linked polymer.

9. The soothing anti-wrinkle moisturizing lotion according to claim 1, characterized in that: The emulsifier includes at least one of cetearyl olivate / sorbitan olivate, hydrogenated lecithin / phytosterols, hydrogenated lysolecithin, and steareth-2 / steareth-21.

10. The method for preparing the soothing, anti-wrinkle and moisturizing emulsion according to any one of claims 1 to 9, characterized in that: The following steps are involved: Mixing pitaya seed oil, tocopherol acetate and emulsifier at 80-90° C. to obtain an oil phase; The chelating agent, humectant and thickener are mixed evenly, and then pitaya stem polysaccharide and deionized water are added, and the mixture is heated to 75-85° C. with stirring, and then the oil phase is added, and the mixture is stirred for 2-8 minutes and then homogenized. When the temperature is cooled to 40-45° C., rose essential oil, pitaya peel extract, p-hydroxyacetophenone, 1,2-hexanediol and pH adjuster are added, and the mixture is stirred evenly to obtain a soothing, anti-wrinkle and moisturizing lotion.

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