Traditional Chinese medicine formula for treating carotid plaque

Through a formula containing a variety of traditional Chinese medicine ingredients, an effective, safe and economical treatment plan is provided to address the uncertainty of existing carotid plaque treatment methods and high risk and high cost issues, and a valid, safe and economical treatment plan is achieved to achieve carotid artery Good therapeutic effect of plaque.

CN119405754APending Publication Date: 2025-02-11温德军
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Patent Information

Application Number
CN202411913556.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-24
Publication Date
2025-02-11

AI Technical Summary

Technical Problem

There are many uncertainties in the treatment methods of carotid artery plaque, the effect of drug treatment is not obvious, the operation risk is high and the cost is high.

Method used

Provide a Chinese medicine formula, including raw astragalus, dinosaur, wolfberry, Panax notoginseng, Gastrodia elata, silkworm, Kermbu, seaweed, earthworm, summer worm, cassia seed, kudzu root, raw hawthorn, polygonum multiflorum, black sheath snake, and tensile Chinese medicine ingredients such as grass, epimedium, raw oysters, vinegar, turtle shell, angelica and centipede are used to treat carotid artery spots by replenishing qi and promoting blood, strengthening the body and eliminating evil, nourishing the liver and kidneys, promoting blood circulation and removing blood stasis, and softening and dispersing nodules. piece.

Benefits of technology

This Chinese medicine formula has good effect on treating and eliminating carotid plaques. It is easy to take, has small doses, small side effects, and low cost. It reduces the medical and economic burden of patients. It is better than the cumbersome and large amount of traditional decoctions and decoctions of traditional Chinese medicine. The disadvantages of high costs and great side effects.

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Abstract

The invention relates to a traditional Chinese medicine formula for treating carotid plaque, and belongs to the field of traditional Chinese medicine formulas. The formula consists of the following traditional Chinese medicines by mass: 30 to 100g of raw astragalus membranaceus, 9 to 15g of earthworm, 10 to 15g of medlar, 7 to 15g of pseudo-ginseng, 10 to 15g of gastrodia elata, 9 to 15g of stiff silkworm, 10 to 15g of kelp, 10 to 15g of seaweed, 10 to 15g of ground beeltle, 10 to 15g of selfheal, 10 to 15g of cassia seed, 15 to 20g of kudzu vine root, 10 to 15g of raw hawthorn, 10 to 15g of prepared fleece flower root, 10 to 15g of zaocys dhumnade, 10 to 15g of lycopodium clavatum, 10 to 15g of epimedium and 15 to 30g of raw oyster. , 10-15 g of vinegar turtle shell, 10-15 g of Chinese angelica, and 2-5 g of centipede. The traditional Chinese medicine formula combines the theories of traditional Chinese medicine and modern medicine and pharmacology, has the effects of tonifying qi and promoting blood circulation, strengthening body resistance to eliminate pathogenic factors, nourishing liver and kidney, promoting blood circulation to remove blood stasis and softening hardness to dissipate stagnation, can be adjusted according to the illness states of different patients, and has good treatment and elimination effects on carotid plaques.
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Description

Technical Field

[0001] The invention belongs to the field of traditional Chinese medicine formulas, and particularly relates to a traditional Chinese medicine formula for treating carotid artery plaques. Background Art

[0002] Carotid plaque is the deposition of fat and calcium on the inner wall of the carotid artery. It is an important manifestation of carotid atherosclerosis and is often found at the bifurcation of the common carotid artery. It is believed to be closely related to the occurrence of ischemic stroke in the elderly. There are many uncertainties in the current treatment of carotid artery. Drug treatment is not effective and can easily damage the functions of other organs. Surgical treatment is risky and expensive, and there are not many hospitals that can perform surgery.

[0003] Traditional Chinese medicine has a history of thousands of years and has good conditioning and treatment effects. It has great advantages in treating carotid artery plaques. Summary of the invention

[0004] The purpose of the present invention is to provide a traditional Chinese medicine formula for treating carotid artery plaque.

[0005] In order to achieve the above object, the present invention provides the following technical solutions: A traditional Chinese medicine formula for treating carotid plaque, characterized in that it is composed of the following traditional Chinese medicines in the following mass proportions: 30-100 grams of raw astragalus, 9-15 grams of earthworm, 10-15 grams of wolfberry, 7-15 grams of Panax notoginseng, 10-15 grams of Gastrodia elata, 9-15 grams of Bombyx batryticatus, 10-15 grams of kelp, 10-15 grams of seaweed, 10-15 grams of Eupolyphaga sinensis, 10-15 grams of Prunella vulgaris, 10-15 grams of Cassia seed, 15-20 grams of Pueraria root, 10-15 grams of raw hawthorn, 10-15 grams of processed Polygonum multiflorum, 10-15 grams of black sheathed snake, 10-15 grams of Lycopodiella cuneata, 10-15 grams of Epimedium, 15-30 grams of raw oyster, 10-15 grams of vinegar turtle shell, 10-15 grams of Angelica sinensis, and 2-5 grams of centipede.

[0006] Preferably, it is composed of the following Chinese medicines in parts by mass: 30 grams of raw astragalus, 9 grams of earthworm, 10 grams of wolfberry, 7 grams of Panax notoginseng, 10 grams of Gastrodia elata, 9 grams of Bombyx batryticatus, 10 grams of kelp, 10 grams of seaweed, 10 grams of Eupolyphaga sinensis, 10 grams of Prunella vulgaris, 10 grams of Cassia seed, 15 grams of Pueraria root, 10 grams of raw hawthorn, 10 grams of processed Polygonum multiflorum, 10 grams of Agkistrodon acutus, 10 grams of Lycopodiella cuneata, 10 grams of Epimedium, 15 grams of raw oyster, 10 grams of vinegar turtle shell, 10 grams of Angelica sinensis, and 2 grams of centipede.

[0007] Preferably, it is composed of the following traditional Chinese medicines in parts by mass: 50 grams of raw astragalus, 12 grams of earthworm, 12 grams of wolfberry, 11 grams of Panax notoginseng, 13 grams of Gastrodia elata, 12 grams of Bombyx batryticatus, 12 grams of kelp, 12 grams of seaweed, 12 grams of Eupolyphaga sinensis, 12 grams of Prunella vulgaris, 12 grams of Cassia seed, 17 grams of Pueraria root, 12 grams of raw hawthorn, 12 grams of processed Polygonum multiflorum, 12 grams of Agkistrodon acutus, 12 grams of Lycopodiella cuneata, 12 grams of Epimedium, 23 grams of raw oyster, 12 grams of vinegar turtle shell, 12 grams of Angelica sinensis, and 3 grams of centipede.

[0008] Preferably, the composition is composed of the following traditional Chinese medicine in parts by mass: 100 grams of raw astragalus, 15 grams of earthworm, 15 grams of wolfberry, 15 grams of Panax notoginseng, 15 grams of Gastrodia elata, 15 grams of Bombyx batryticatus, 15 grams of kelp, 15 grams of seaweed, 15 grams of Eupolyphaga sinensis, 15 grams of Prunella vulgaris, 15 grams of Cassia seed, 20 grams of Pueraria root, 15 grams of raw hawthorn, 15 grams of processed Polygonum multiflorum, 15 grams of Agkistrodon acutus, 15 grams of Lycopodiella cuneata, 15 grams of Epimedium, 30 grams of raw oyster, 15 grams of vinegar turtle shell, 15 grams of Angelica sinensis, and 5 grams of centipede.

[0009] The above-mentioned Chinese herbal ingredients have the following effects: Raw Astragalus: It has the effects of replenishing Qi and strengthening the exterior, expelling toxins and pus, promoting diuresis, and promoting tissue regeneration.

[0010] Earthworm: It has the effects of clearing away heat and calming the nerves, unblocking meridians, relieving asthma and promoting diuresis.

[0011] Lycium barbarum: It has the effects of promoting immunity, anti-aging, anti-tumor, scavenging free radicals, anti-fatigue, anti-radiation, liver protection, and protecting and improving reproductive function.

[0012] Panax notoginseng: It has the effects of dispersing blood stasis, stopping bleeding, reducing swelling and relieving pain.

[0013] Gastrodia elata: It has the effect of calming wind and calming the nerves. It can effectively treat dizziness, dark spots in the eyes, headaches, numbness of limbs, hemiplegia, and slurred speech.

[0014] Bombyx batryticatus: It has the effects of calming wind and stopping convulsions, dispelling wind and relieving pain, and resolving phlegm and dispersing nodules.

[0015] Kelp: It has the effects of eliminating phlegm, softening hard masses, dispersing lumps, promoting diuresis and reducing swelling.

[0016] Seaweed: It has the effects of eliminating phlegm, softening hard masses, dispersing lumps, promoting diuresis and reducing swelling.

[0017] Earthworm: It has the effects of breaking up blood stasis, repairing tendons and bones, treating tendon and bone fractures, blood stasis, amenorrhea, and abdominal masses.

[0018] Prunella Vulgaris: It has the effect of clearing liver fire and dispersing blood stasis.

[0019] Cassia seed: has the effects of clearing away heat, improving eyesight, moistening the intestines and promoting bowel movements.

[0020] Pueraria root: It has the functions of relieving muscles and reducing fever, promoting body fluid, clearing rashes, raising yang and stopping diarrhea.

[0021] Raw hawthorn: has the effect of eliminating food accumulation and removing blood stasis.

[0022] Prepared Polygonum multiflorum: It has the effects of nourishing the liver and kidneys, improving the essence and blood, blackening the hair, strengthening the tendons and bones, resolving turbidity and reducing fat.

[0023] Black Sheathed Snake: It has the effects of dispelling wind, unblocking meridians and stopping spasms.

[0024] Stretching grass: It has the effect of dispelling wind and dampness, relaxing muscles and activating blood circulation.

[0025] Epimedium: It has the effects of replenishing kidney yang, strengthening muscles and bones, and eliminating rheumatism.

[0026] Raw oysters: have astringent, sedative, detoxifying and analgesic effects.

[0027] Vinegar turtle shell: has the effects of astringency, detoxification, dispersing blood stasis and relieving pain.

[0028] Angelica: It has the effects of regulating the body's immune function, anti-cancer, blood-tonifying and activating blood circulation, skin care and beauty, blood-tonifying and activating blood circulation, anti-bacterial, anti-atherosclerosis, regulating menstruation and relieving pain, and moisturizing the intestines and promoting bowel movements.

[0029] Centipede: It has the effects of extinguishing wind and stopping convulsions, detoxifying and dispersing nodules, and unblocking meridians and relieving pain.

[0030] The beneficial effects of the present invention are: Combining the theories of traditional Chinese medicine and modern medicine, it has the effects of replenishing qi and promoting blood circulation, strengthening the body and eliminating evil, nourishing the liver and kidney, promoting blood circulation and removing blood stasis, softening and dispersing nodules. The prescription ratio can be adjusted according to the conditions of different patients, and it has a good treatment and elimination effect on carotid artery plaques. This formula is easy to take, with a small dosage, few side effects, and low cost, which reduces the medical economic burden of patients. It is better than the disadvantages of decocting Chinese medicine, which is cumbersome, large dosage, high cost, and large side effects. Long-term use makes patients more willing to accept it.

[0031] The above description is only an overview of the technical solution of the present invention. In order to more clearly understand the technical means of the present invention and implement it according to the contents of the specification, the following is a detailed description of the preferred embodiments of the present invention in conjunction with the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] Figure 1 This is the ultrasound diagnosis report of Ms. Shi, a patient in the experimental example of the present invention, before taking the medicine; Figure 2 This is the ultrasound diagnosis report of Ms. Shi, a patient in the experimental example of the present invention, after taking the medicine; Figure 3 This is the ultrasound diagnosis report of Ms. Yang, a patient in the experimental example of the present invention, before taking the medicine; Figure 4 This is the ultrasound diagnosis report of Ms. Yang, a patient in the experimental example of the present invention, before taking the medicine; Figure 5 This is the ultrasound diagnosis report of Ms. Li, a patient in the experimental example of the present invention, before taking the medicine; Figure 6 This is the ultrasound diagnosis report of Ms. Li, a patient in the experimental example of the present invention, before taking the medicine; Figure 7 This is the ultrasound diagnosis report of Ms. Wang, a patient in the experimental example of the present invention, before taking the medicine; Figure 8 This is the ultrasound diagnosis report of Ms. Wang, a patient in the experimental example of the present invention, before taking the medicine; Fig. 9 This is the ultrasound diagnosis report of Ms. He, a patient in the experimental example of the present invention, before taking the medicine; Fig.10 This is the ultrasound diagnosis report of Ms. He, a patient in the experimental example of the present invention, before taking the medicine. DETAILED DESCRIPTION

[0033] The technical solution of the present invention will be described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0034] In addition, the technical features involved in the different embodiments of the present invention described below can be combined with each other as long as they do not conflict with each other. Example

[0035] A traditional Chinese medicine formula for treating carotid artery plaques, consisting of the following traditional Chinese medicines in parts by weight: 30 grams of raw astragalus, 9 grams of earthworm, 10 grams of wolfberry, 7 grams of Panax notoginseng, 10 grams of Gastrodia elata, 9 grams of Bombyx batryticatus, 10 grams of kelp, 10 grams of seaweed, 10 grams of Eupolyphaga sinensis, 10 grams of Prunella vulgaris, 10 grams of Cassia seed, 15 grams of Pueraria root, 10 grams of raw hawthorn, 10 grams of processed Polygonum multiflorum, 10 grams of Agkistrodon acutus, 10 grams of Lycopodiella cuneata, 10 grams of Epimedium, 15 grams of raw oyster, 10 grams of vinegar turtle shell, 10 grams of Chinese angelica, and 2 grams of centipede.

[0036] Grind the above-mentioned Chinese medicine into fine powder with a grinder or beat it into fine powder with a pulverizer, and take it with warm water after meals, twice a day, 5 grams each time. Avoid raw, cold and spicy food during the period of taking it, and eat less oil, salt and other foods that damage blood vessels and blood. This Chinese medicine can also be processed into Chinese medicine granules, Chinese medicine water pills, Chinese medicine tablets, Chinese medicine capsules or Mongolian medicine powder for oral administration. Example

[0037] A traditional Chinese medicine formula for treating carotid artery plaque, consisting of the following traditional Chinese medicines in parts by mass: 50 grams of raw astragalus, 12 grams of earthworm, 12 grams of wolfberry, 11 grams of Panax notoginseng, 13 grams of Gastrodia elata, 12 grams of Bombyx batryticatus, 12 grams of kelp, 12 grams of seaweed, 12 grams of Eupolyphaga sinensis, 12 grams of Prunella vulgaris, 12 grams of Cassia seed, 17 grams of Pueraria root, 12 grams of raw hawthorn, 12 grams of processed Polygonum multiflorum, 12 grams of Agkistrodon acutus, 12 grams of Lycopodiella cuneata, 12 grams of Epimedium, 23 grams of raw oyster, 12 grams of vinegar turtle shell, 12 grams of Chinese angelica, and 3 grams of centipede.

[0038] The administration method in this embodiment is the same as that in embodiment 1. Example

[0039] A traditional Chinese medicine formula for treating carotid artery plaque, consisting of the following traditional Chinese medicines in parts by mass: 100 grams of raw astragalus, 15 grams of earthworm, 15 grams of wolfberry, 15 grams of Panax notoginseng, 15 grams of Gastrodia elata, 15 grams of Bombyx batryticatus, 15 grams of kelp, 15 grams of seaweed, 15 grams of Eupolyphaga sinensis, 15 grams of Prunella vulgaris, 15 grams of Cassia seed, 20 grams of Pueraria root, 15 grams of raw hawthorn, 15 grams of processed Polygonum multiflorum, 15 grams of Snakehead aconite, 15 grams of Lycopodiella cuneata, 15 grams of Epimedium, 30 grams of raw oyster, 15 grams of Vinegar-scented turtle shell, 15 grams of Angelica sinensis, and 5 grams of centipede.

[0040] The administration method in this embodiment is the same as that in embodiment 1.

[0041] The therapeutic effect of the Chinese medicine preparation of the present invention is illustrated below through clinical observation.

[0042] 1. Please see Figure 1-2 Ms. Shi, 59 years old, was found to have 0.2*1.0cm and 0.2*0.6 low echo plaques on the posterior wall of the left carotid artery near the bifurcation after ultrasound examination in our hospital in October 2022. The patient started taking the prescription shown in the present invention for 4 months in November 2022; the ultrasound diagnosis report in March 2023 showed that a 0.2*0.6 low echo plaque was detected on the posterior wall of the left carotid artery near the bifurcation, and the internal echo was uniform. It can be seen that the plaque on the left side of the carotid artery has been significantly improved.

[0043] 2. Please see Figure 3-4 Ms. Yang, 69 years old, was found to have a 0.2*0.5cm low-echo plaque on the posterior wall of the right carotid artery near the bifurcation after ultrasound examination in our hospital in December 2022. The patient started taking the prescription shown in the present invention for 23 months in December 2022; the ultrasound diagnosis report in October 2024 showed that no plaque echo was found in the lumen, the blood flow was smooth, and the filling was good. It can be seen that the plaque on the right side of the carotid artery was effectively cured.

[0044] 3. Please see Figure 5-6Ms. Li, 71 years old, was found to have a 4.9*1.9cm low-echo plaque on the posterior wall of the bifurcation of the right common carotid artery after ultrasound examination in our hospital in March 2024. The patient started taking the prescription of the present invention for 8 months in March 2024. The ultrasound diagnosis report in October 2024 showed that no plaque echo was found in the lumen, the blood flow was smooth, and the filling was good. It can be seen that the plaque of the right common carotid artery was effectively cured.

[0045] 4. Please see Figure 7-8 Ms. Wang, 72 years old, underwent ultrasound examination in our hospital in May 2022. It was found that a 0.38*0.21cm low-echo plaque was visible on the posterior wall of the left common carotid artery near the bifurcation, and a 0.39*0.15cm low-echo plaque was visible on the posterior wall of the right common carotid artery near the bifurcation. The patient started taking the prescription shown in the present invention for 20 months in May 2022; the ultrasound diagnosis report in February 2024 showed that no plaque echo was found in the lumen, the blood flow was smooth, and the filling was good, which showed that the patient's carotid artery plaque had been effectively cured.

[0046] 5. Please see Figure 9-10 Ms. He, 66 years old, was found to have a 0.3*0.17cm strong echo plaque on the posterior wall of the right common carotid artery near the bifurcation after ultrasound examination in our hospital in May 2022. The patient started taking the prescription shown in the present invention for 26 months in May 2022; the ultrasound diagnosis report in October 2024 showed that no plaque echo was found in the lumen, the blood flow was smooth, and the filling was good, which showed that the patient's carotid artery plaque had been effectively cured.

[0047] From the above experimental examples, it can be seen that taking the Chinese medicine formula shown in the present invention for 4-6 months has a significant improvement effect on the treatment of carotid artery plaques, and taking it for 20-24 months can effectively cure carotid artery plaques, which is a significant improvement compared to the prior art.

[0048] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0049] The above-mentioned embodiments only express several implementation methods of the present invention, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the invention patent. It should be pointed out that, for ordinary technicians in this field, several variations and improvements can be made without departing from the concept of the present invention, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the patent of the present invention shall be subject to the attached claims.

Claims

1. A Chinese medicine formula for treating carotid artery plaque, characterized in that: It is composed of Chinese medicine in the following mass proportions: 30-100 grams of raw astragalus, 9-15 grams of earthworm, 10-15 grams of wolfberry, 7-15 grams of Panax notoginseng, 10-15 grams of Gastrodia elata, 9-15 grams of Bombyx batryticatus, 10-15 grams of kelp, 10-15 grams of seaweed, 10-15 grams of earthworm, 10-15 grams of selfheal, 10-15 grams of cassia seed, 15-20 grams of Pueraria root, 10-15 grams of raw hawthorn, 10-15 grams of processed Polygonum multiflorum, 10-15 grams of black sheathed snake, 10-15 grams of Lycopodiella cuneata, 10-15 grams of Epimedium, 15-30 grams of raw oyster, 10-15 grams of vinegar turtle shell, 10-15 grams of Angelica sinensis, and 2-5 grams of centipede.

2. The Chinese medicine formula for treating carotid artery plaque according to claim 1, characterized in that: The following parts by weight of Chinese medicine Ingredients: 30g raw Astragalus, 9g earthworm, 10g wolfberry, 7g Panax notoginseng, 10g Gastrodia, 9g Bombyx batryticatus, 10g kelp, 10g seaweed, 10g earthworm, 10g selfheal, 10g cassia seed, 15g Pueraria root, 10g raw hawthorn, 10g processed Polygonum multiflorum, 10g black sheathed snake, 10g Lycopodiella cuneata, 10g Epimedium, 15g raw oyster, 10g vinegar turtle shell, 10g angelica, and 2g centipede.

3. The Chinese medicine formula for treating carotid artery plaque according to claim 1, characterized in that: The composition is composed of the following Chinese medicines in parts by weight: 50 grams of raw astragalus, 12 grams of earthworm, 12 grams of wolfberry, 11 grams of Panax notoginseng, 13 grams of Gastrodia elata, 12 grams of Bombyx batryticatus, 12 grams of kelp, 12 grams of seaweed, 12 grams of Eupolyphaga sinensis, 12 grams of Prunella vulgaris, 12 grams of Cassia seed, 17 grams of Pueraria root, 12 grams of raw hawthorn, 12 grams of processed Polygonum multiflorum, 12 grams of Agkistrodon acutus, 12 grams of Lycopodiella cuneata, 12 grams of Epimedium, 23 grams of raw oyster, 12 grams of vinegar turtle shell, 12 grams of Angelica sinensis, and 3 grams of centipede.

4. The Chinese medicine formula for treating carotid plaque according to claim 1, characterized in that: It is composed of the following Chinese medicines in parts by weight: 100 grams of raw astragalus, 15 grams of earthworm, 15 grams of wolfberry, 15 grams of Panax notoginseng, 15 grams of Gastrodia elata, 15 grams of Bombyx batryticatus, 15 grams of kelp, 15 grams of seaweed, 15 grams of Eupolyphaga sinensis, 15 grams of Prunella vulgaris, 15 grams of Cassia seed, 20 grams of Pueraria root, 15 grams of raw hawthorn, 15 grams of processed Polygonum multiflorum, 15 grams of Agkistrodon acutus, 15 grams of Lycopodiella cuneata, 15 grams of Epimedium, 30 grams of raw oyster, 15 grams of vinegar turtle shell, 15 grams of Angelica sinensis, and 5 grams of centipede.