Acne removal composition and application thereof

Abstract

The invention relates to an acne-removing composition and application thereof. The acne-removing composition is prepared from a sweet osmanthus extract, zinc pyrrolidone carboxylate, coated salicylic acid, quaternary ammonium salt-73, 0-cymene-5-ol, oat beta-glucan, nicotinamide and an oat kernel extract. Starting from acne formation factors, various active components are reasonably compounded, the obtained composition is fresh and oil-free, acne formation can be inhibited from multiple aspects of oil control, anti-inflammation, bacteriostasis, pore dredging and the like, the purpose of comprehensive acne removal is achieved, the acne removal effect is outstanding, and the composition has the advantages of being stable and free of color change after being added into a product and has a good application prospect. And a subject can have a pleasant sensory experience in use.

Description

Technical Field

[0001] The present invention relates to the technical field of cosmetics, and in particular to an anti-acne composition and application thereof. Background Art

[0002] Acne, also known as "pimples", "acne" or "blackheads", is a common skin problem that plagues modern people, especially teenagers. There are three factors that cause it: excessive oil secretion is a prerequisite for acne. Excessive skin oil secretion and continuous accumulation and poor discharge cause pore blockage, which leads to the accelerated reproduction of acne bacteria that prefer an anaerobic environment; pore blockage is a key factor in acne, and the oxygen-deficient hair follicles will become an excellent breeding ground for acne; and the severity of inflammation determines the time of acne. If there is inflammation, there will be acne. If the inflammation is not eliminated, the acne cannot be completely eliminated. Once the skin is inflamed, it will cause local swelling, narrowing of the hair follicles, aggravating pore blockage and causing acne.

[0003] The concentration of acne removal products on the market today is too low to achieve the desired acne removal effect, while a high concentration can damage the skin and cause skin allergies. Or acne removal products contain added pigments, flavors, cooling ingredients (menthol, camphor tincture), coconut oil, lanolin, most plant oils and sulfur-containing surfactants, which can cause skin irritation and recurring acne for consumers.

[0004] Therefore, it is an urgent problem to be solved in the art to provide a refreshing oil-free cosmetic composition designed for the factors that cause acne, inhibit the formation of acne from multiple aspects such as oil control, anti-inflammation and pore cleaning, and fully achieve the purpose of acne removal. Summary of the invention

[0005] In order to solve the above technical problems, the present invention provides an acne-removing composition and its application. The present invention starts from the formation factors of acne, rationally compounds multiple active components, and the obtained composition is refreshing and oil-free, and can inhibit the formation of acne from multiple aspects such as oil control, anti-inflammatory, antibacterial, and pore dredging, so as to achieve the purpose of comprehensive acne removal, and the acne removal effect is outstanding. Moreover, the composition has the advantages of being stable and not discolored when added to the product, so that the subjects can achieve a pleasant sensory experience during use.

[0006] To achieve this object, the present invention adopts the following technical solutions:

[0007] In a first aspect, the present invention provides an anti-acne composition, comprising osmanthus extract, zinc pyrrolidone carboxylate, encapsulated salicylic acid, quaternary ammonium salt-73, 0-cymene-5-ol, oat β-glucan, niacinamide and oat kernel extract.

[0008] In the present invention, the osmanthus extract has a good preventive effect on the greasiness caused by excessive oil secretion on the face and hair, and can make the skin and hair refreshing and non-greasy.

[0009] In the present invention, zinc pyrrolidone carboxylate has the effects of accelerating wound repair, improving epidermal regeneration rate and anti-inflammatory properties, and can penetrate the dermis of the skin, regulate sebaceous gland secretion, decompose accumulated grease and clean pores.

[0010] In the present invention, the encapsulated salicylic acid can make the skin dry quickly, promote the shedding of aging keratin on the skin, and inhibit the bacteria that cause acne.

[0011] In the present invention, quaternary ammonium salt-73 and 0-cymene-5-ol have good water solubility and good permeability to the skin, can effectively fight acne, inhibit the reproduction of acrylic acid bacteria, prevent skin roughness, inhibit excessive sebum secretion, have a broad spectrum of bactericidal effects, have astringent properties, and shrink pores.

[0012] In the present invention, oat beta-glucan is a water-soluble non-starch polysaccharide, which has the effects of anti-wrinkle, moisturizing and immune activation, can promote wound healing, and also has the effect of improving skin smoothness, so that skin elasticity continues to increase over time.

[0013] In the present invention, niacinamide can inhibit the generation of free radicals, reduce oxidative stress, prevent skin aging, and at the same time reduce the inflammatory response of the skin, relieve skin allergies, redness and swelling and other symptoms. In addition, it can also reduce sebum secretion, regulate oil balance, and have a certain improvement effect on acne skin.

[0014] In the present invention, the oat kernel extract has anti-allergic and soothing effects, and can be used to relieve skin irritation and reduce skin discomfort.

[0015] The present invention starts from the formation factors of acne and rationally compounds a variety of active components. The obtained composition is refreshing and oil-free, and can inhibit the formation of acne from multiple aspects such as oil control, anti-inflammatory, antibacterial, and pore unblocking, thereby achieving the purpose of comprehensive acne removal. The acne removal effect is outstanding, and the composition added to the product has the advantage of being stable and not discolored, so that the subjects can achieve a pleasant sensory experience during use.

[0016] Preferably, the anti-acne composition comprises, by weight, 80-100 parts of osmanthus extract, 0.5-5 parts of zinc pyrrolidonecarboxylate, 0.5-5 parts of encapsulated salicylic acid, 0.00125-0.0035 parts of quaternary ammonium salt-73, 0.0275-0.065 parts of 0-cymene-5-ol, 1-5 parts of oat β-glucan, 2-10 parts of niacinamide and 0.1-0.5 parts of oat kernel extract.

[0017] In the present invention, by weight, the osmanthus extract can be 82 parts, 85 parts, 88 parts, 90 parts, 92 parts, 95 parts, 98 parts, etc.; the zinc pyrrolidone carboxylate can be 0.8 parts, 1 parts, 2 parts, 3 parts, 4 parts, etc.; the encapsulated salicylic acid can be 0.8 parts, 1 parts, 2 parts, 3 parts, 4 parts, etc.; the quaternary ammonium salt-73 can be 0.0015 parts, 0.00175 parts, 0.002 parts, 0.00225 parts, 0.0025 parts, 0.00275 parts, 0.00 3 parts, 0.00325 parts, etc.; 0-cymene-5-ol can be 0.03 parts, 0.04 parts, 0.05 parts, 0.06 parts, etc.; oat β-glucan can be 1.5 parts, 2 parts, 2.5 parts, 3 parts, 3.5 parts, 4 parts, 4.5 parts, etc.; niacinamide can be 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, etc.; oat kernel extract can be 0.15 parts, 0.2 parts, 0.25 parts, 0.3 parts, 0.35 parts, 0.4 parts, 0.45 parts, etc.

[0018] Preferably, the preparation method of the osmanthus extract comprises the following steps:

[0019] The fresh osmanthus is subjected to vacuum constant temperature extraction and solid-liquid separation to obtain the osmanthus extract.

[0020] Preferably, the extraction drying coefficient K is 1.1-1.3 (for example, it can be 1.12, 1.15, 1.2, 1.25, 1.28, etc.), the extraction temperature is 45-55°C (for example, it can be 46°C, 48°C, 50°C, 52°C, 54°C, etc.), the extraction pressure is 0.068-0.08MPa (for example, it can be 0.07MPa, 0.072MPa, 0.076MPa, 0.078MPa, etc.), and the extraction time is 3.5-4h (for example, it can be 3.6h, 3.7h, 3.8h, 3.9h, etc.).

[0021] The preparation method of the osmanthus extract provided by the invention does not add any solvent in the whole process, and the obtained product is a pure natural plant extract, which is safe and non-irritating to the skin.

[0022] In a second aspect, the present invention provides a use of the anti-acne composition according to the first aspect in the preparation of cosmetics.

[0023] Preferably, the mass fraction of the anti-acne composition in the cosmetic is 50-95%, for example, 60%, 70%, 80%, 90%, etc.

[0024] Preferably, the cosmetics include facial masks, lotions, toners, creams, essences, make-up removers or cleansing products.

[0025] In a third aspect, the present invention provides an acne-removing essence, which comprises a thickener, a moisturizer, a pH regulator and a skin conditioner; the skin conditioner comprises the acne-removing composition described in the first aspect.

[0026] Preferably, the anti-acne essence comprises, by mass percentage, 0.1-1% of a thickener, 5-15% of a moisturizer, 0.1-1% of a pH regulator, and 70-95% of a skin conditioner.

[0027] In the present invention, in terms of mass percentage, the thickener can be 0.2%, 0.3%, 0.4%, 0.5%, 0.6%, 0.7%, 0.8%, 0.9% etc.; the moisturizer can be 6%, 8%, 10%, 12%, 14% etc.; the pH adjuster can be 0.2%, 0.3%, 0.4%, 0.5%, 0.6%, 0.7%, 0.8%, 0.9% etc.; the skin conditioner can be 74%, 78%, 82%, 86%, 90% etc.

[0028] Preferably, the thickener comprises any one of hydroxyethyl cellulose, hydroxypropyl starch phosphate, sodium alginate, polyacrylamide or xanthan gum, or a combination of at least two thereof.

[0029] Preferably, the moisturizing agent includes any one of sodium hyaluronate, trehalose, 1,2-pentanediol, 1,2-hexanediol, 1,2-propylene glycol, dipropylene glycol, 1,3-butylene glycol or caprylyl glycol, or a combination of at least two thereof.

[0030] Preferably, the pH adjuster comprises sodium citrate.

[0031] In a fourth aspect, the present invention provides a method for preparing the anti-acne essence according to the third aspect, characterized in that the preparation method comprises the following steps:

[0032] The thickener, moisturizer, pH regulator and osmanthus extract, zinc pyrrolidone carboxylate, encapsulated salicylic acid and niacinamide in the skin conditioner are mixed, heated and stirred, and the system is cooled after being dissolved, and quaternary ammonium salt-73, 0-cymene-5-ol, oat β-glucan and oat kernel extract in the skin conditioner are added to obtain the acne-removing essence.

[0033] Preferably, the heating temperature is 70-85°C, for example, 72°C, 74°C, 76°C, 78°C, 80°C, 82°C, 84°C, etc.

[0034] Preferably, the temperature is lowered to 40-50°C, for example, 42°C, 44°C, 46°C, 48°C, etc.

[0035] Compared with the prior art, the present invention has at least the following beneficial effects:

[0036] The present invention starts from the formation factors of acne and rationally compounds a variety of active components. The obtained composition is refreshing and oil-free, and can inhibit the formation of acne from multiple aspects such as oil control, anti-inflammatory, antibacterial, and pore unblocking, thereby achieving the purpose of comprehensive acne removal. The acne removal effect is outstanding, and the composition added to the product has the advantage of being stable and not discolored, so that the subjects can achieve a pleasant sensory experience during use. DETAILED DESCRIPTION

[0037] For the convenience of understanding the present invention, the present invention lists the following embodiments. It should be understood by those skilled in the art that the embodiments are only to help understand the present invention and should not be regarded as specific limitations of the present invention.

[0038] The sources of ingredients in the following examples and comparative examples are as follows:

[0039] Zinc pyrrolidone carboxylate was purchased from Tianjin Kebaisi Technology Co., Ltd.;

[0040] Encapsulated salicylic acid was purchased from Ningbo Xiangshen Biochemical Co., Ltd.;

[0041] Oat β-glucan was purchased from Qinxiang New Materials (Guangzhou) Co., Ltd.;

[0042] Oat kernel extract was purchased from Fanlin Chemical Technology (Guangzhou) Co., Ltd. with a specification of 10:1.

[0043] The weight percentages of the zinc pyrrolidonecarboxylate, oat β-glucan, and oat kernel extract involved are all calculated based on the actual content of the effective ingredients contained in the commercially available raw materials. The commercially available raw materials may also selectively contain any one or a combination of at least two of solvents, fillers, diluents, stabilizers, pH adjusters, antibacterial agents, antioxidants, or impurities within the permitted range.

[0044] The preparation methods of the osmanthus extract in the embodiments and comparative examples are as follows:

[0045] Fresh osmanthus was extracted for 4 hours at a drying coefficient K of 1.3, a temperature of 55° C., and a pressure of 0.07 MPa to obtain an osmanthus extract (yield 65%).

[0046] Other raw materials are common commercially available products and will not be described in detail here.

[0047] Example 1

[0048] The present embodiment provides an anti-acne composition, which comprises, by weight, 85 parts of osmanthus extract, 2.5 parts of zinc pyrrolidone carboxylate, 2.5 parts of encapsulated salicylic acid, 0.002 parts of quaternary ammonium salt-73, 0.05 parts of 0-cymene-5-ol, 2.5 parts of oat β-glucan, 6 parts of niacinamide and 0.3 parts of oat kernel extract.

[0049] Example 2

[0050] The present embodiment provides an anti-acne composition, which comprises, by weight, 80 parts of osmanthus extract, 0.5 parts of zinc pyrrolidone carboxylate, 0.5 parts of encapsulated salicylic acid, 0.00125 parts of quaternary ammonium salt-73, 0.0275 parts of 0-cymene-5-ol, 1 part of oat β-glucan, 2 parts of niacinamide and 0.1 parts of oat kernel extract.

[0051] Example 3

[0052] The present embodiment provides an anti-acne composition, which includes, by weight, 100 parts of osmanthus extract, 5 parts of zinc pyrrolidone carboxylate, 5 parts of encapsulated salicylic acid, 0.0035 parts of quaternary ammonium salt-73, 0.065 parts of 0-cymene-5-ol, 5 parts of oat β-glucan, 10 parts of niacinamide and 0.5 parts of oat kernel extract.

[0053] Comparative Example 1

[0054] This comparative example provides an anti-acne composition, which differs from Example 1 only in that it does not contain zinc pyrrolidone carboxylate, and its weight proportions are distributed according to the ratio of encapsulated salicylic acid and niacinamide.

[0055] Comparative Example 2

[0056] This comparative example provides an anti-acne composition, which differs from Example 1 only in that it does not contain encapsulated salicylic acid, and its weight proportions are distributed according to the ratio of zinc pyrrolidone carboxylate and niacinamide.

[0057] Comparative Example 3

[0058] This comparative example provides an anti-acne composition, which differs from Example 1 only in that niacinamide is not contained, and its weight proportions are distributed according to the ratio of encapsulated salicylic acid and zinc pyrrolidonecarboxylate.

[0059] Comparative Example 4

[0060] This comparative example provides an anti-acne composition, which differs from Example 1 only in that it does not contain 0-cymene-5-ol, and its weight parts are distributed according to the ratio of quaternary ammonium salt-73 and encapsulated salicylic acid.

[0061] Comparative Example 5

[0062] This comparative example provides an anti-acne composition, which differs from Example 1 only in that it does not contain quaternary ammonium salt-73, and its weight parts are distributed according to the ratio of 0-cymene-5-ol and encapsulated salicylic acid.

[0063] Comparative Example 6

[0064] This comparative example provides an anti-acne composition, which differs from Example 1 only in that it does not contain encapsulated salicylic acid, and its weight parts are distributed according to the ratio of quaternary ammonium salt-73 and 0-cymene-5-ol.

[0065] Comparative Example 7

[0066] This comparative example provides an anti-acne composition, which differs from Example 1 only in that it does not contain oat β-glucan, and its weight proportions are distributed according to the ratio of oat kernel extract and niacinamide.

[0067] Comparative Example 8

[0068] This comparative example provides an anti-acne composition, which differs from Example 1 only in that it does not contain oat kernel extract, and its weight parts are distributed according to the ratio of oat β-glucan and niacinamide.

[0069] Comparative Example 9

[0070] This comparative example provides an anti-acne composition, which differs from Example 1 only in that niacinamide is not contained, and its weight parts are distributed according to the ratio of oat β-glucan and oat kernel extract.

[0071] Comparative Example 10

[0072] This comparative example provides an anti-acne composition, which is different from Example 1 only in that the osmanthus extract is replaced by an equal weight portion of deionized water.

[0073] Application Example 1

[0074] This application example provides an acne-removing essence, the formula of which is as follows:

[0075]

[0076] The method for preparing the anti-acne essence comprises the following steps: mixing a thickener, a moisturizer, a pH regulator and osmanthus extract, zinc pyrrolidone carboxylate, encapsulated salicylic acid and niacinamide in a skin conditioner, heating to 85° C., stirring to dissolve, then cooling to 45° C., adding quaternary ammonium salt-73, 0-cymene-5-ol, oat β-glucan and oat kernel extract in the skin conditioner to obtain the anti-acne essence.

[0077] Application Example 2

[0078] This application example provides an acne-removing essence, the formula of which is as follows:

[0079]

[0080] The method for preparing the anti-acne essence comprises the following steps: mixing a thickener, a moisturizer, a pH regulator and osmanthus extract, zinc pyrrolidone carboxylate, encapsulated salicylic acid and niacinamide in a skin conditioner, heating to 75° C., stirring to dissolve, then cooling to 50° C., adding quaternary ammonium salt-73, 0-cymene-5-ol, oat β-glucan and oat kernel extract in the skin conditioner to obtain the anti-acne essence.

[0081] Application Example 3

[0082] This application example provides an acne-removing essence, the formula of which is as follows:

[0083]

[0084]

[0085] The method for preparing the anti-acne essence comprises the following steps: mixing a thickener, a moisturizer, a pH regulator and osmanthus extract, zinc pyrrolidone carboxylate, encapsulated salicylic acid and niacinamide in a skin conditioner, heating to 70° C., stirring to dissolve, then cooling to 40° C., adding quaternary ammonium salt-73, 0-cymene-5-ol, oat β-glucan and oat kernel extract in the skin conditioner to obtain the anti-acne essence.

[0086] Comparative Application Examples 1-10

[0087] The above comparative application examples respectively provide an anti-acne essence, which differs from Application Example 1 only in that the skin conditioner is replaced by the compositions provided in Comparative Examples 1-10 respectively; the preparation method refers to Application Example 1.

[0088] Test Example 1

[0089] Skin oil content test

[0090] Experimental principle: Grease test is based on the principle of photometer. Choose a special matte tape with a thickness of 0.1mm, which can quickly absorb the grease on human skin. Due to the effect of grease, the matte tape becomes translucent. The more grease absorbed, the greater the light transmittance. The light transmittance is measured with a photometer. According to the change in light transmittance before and after the matte tape, the oil content of the skin can be measured.

[0091] Test method: 70 volunteers, ladies aged 20-50 years old, were selected and randomly divided into 7 groups, 10 people in each group. Each group took an appropriate amount of the anti-acne essence provided in Application Examples 1-3 and Comparative Application Examples 1-4 to wipe the forehead. The technicians used the skin oil test probe to test the test site 5 times, took the average value, and statistically measured the measured values. The mean method was used to analyze the changing pattern and persistence of skin oil secretion. The specific test results are shown in Table 1.

[0092] Table 1

[0093]

[0094] From the test results in Table 1, it can be seen that the acne-removing essence provided by the present invention has an excellent effect of inhibiting the secretion of sebum, can effectively regulate the water-oil balance of the skin, and oil will not recur. By comparing Application Example 1 with Comparative Application Examples 1-3, it can be seen that the three components of zinc pyrrolidone carboxylate, encapsulated salicylic acid and niacinamide in the acne-removing composition provided by the present invention have a synergistic technical effect in oil control; by comparing Application Example 1 with Comparative Application Example 10, it can be seen that osmanthus extract has an excellent oil control effect, and when not added, the oil control effect is significantly reduced.

[0095] Test Example 2

[0096] Pore ​​index test

[0097] Test principle: The present invention uses the ANTERA-3D skin measuring instrument, which collects skin conditions through 24 LED lights of 7 different wavelengths and can reconstruct a real 3D model of the skin. By analyzing the facial collection image of ANTERA-3D through software, relevant data such as total pore volume, average pore area, and pore count can be obtained to help analyze the pore status of the skin surface.

[0098] Test method: 60 volunteers, ladies aged 20-50 years old, were randomly divided into 6 groups, each with 10 people. Each group used one of the essences provided in Application Examples 1-3 and Comparative Application Examples 4-6 of the present invention, and applied and massaged on the clean face at 8 am and 5 pm every day until completely absorbed. Before the test, the face was cleaned first, and then the face was collected and recorded as W0 by ANTERA-3D after sitting in a room with an ambient temperature of 25°C and a humidity of 50% for 15 minutes. Subsequently, a return visit test was conducted 1 week (W1), 2 weeks (W2), and 4 weeks (W4) after using the product, and the images were collected for analysis.

[0099] By analyzing the facial images collected by volunteers, the total pore volume (mm 3 ), average pore area (mm 2 ) and data analysis and summary of pore counts, the results are shown in Table 2 below.

[0100] Table 2

[0101]

[0102]

[0103] The test results in Table 2 show that the anti-acne essence provided by the present invention has an excellent effect of clearing and cleaning pores, and has the effect of reducing the total volume of pores (mm 3 ), average pore area (mm 2 ) and the technical effect of pore counting. And through the comparison of application example 1 and comparative application examples 4-6, it can be seen that the quaternary ammonium salt-73, 0-cymene-5-ol and encapsulated salicylic acid in the present invention have a synergistic technical effect in dredging and cleaning pores and reducing the volume and number of pores.

[0104] Test Example 3

[0105] Antibacterial test

[0106] The massive proliferation of Propionibacterium acnes is one of the important factors causing the formation and aggravation of acne. Therefore, if skin care products have the effect of inhibiting Propionibacterium acnes, they can prevent the formation of acne and inhibit the development of acne to a certain extent. Determining the inhibitory effect of the test substance on Propionibacterium acnes can reflect its acne-removing effect.

[0107] Test method: Prepare the product of Application Example 1 into a 100 mg / mL sample, prepare ten test tubes (the first of which is an empty test tube, and the other nine test tubes are filled with 5 mL of distilled water), add 5 mL of sample to the first test tube; then draw 5 mL of sample into the second test tube and mix; then draw 5 mL of diluent into the third test tube, and so on, when it comes to the tenth test tube, draw 5 mL from the tenth test tube and discard it. Add 0.1 mL of Propionibacterium acnes bacterial solution (100,000 cfu / mL) to each of the ten test tubes, mix well, place in a 37°C incubator for 24 hours, observe the clear test tubes, and determine the minimum inhibitory concentration MIC.

[0108] The operations of Application Examples 2-3 and Comparative Application Examples 4-6 are the same as above, and the results are shown in Table 3.

[0109] Table 3

[0110]

[0111]

[0112] It can be seen from the test results in Table 3 that the acne-removing essence provided by the present invention has a good inhibitory effect on Propionibacterium acnes, and through the comparison of Application Example 1 and Comparative Application Examples 4-6, it can be seen that the quaternary ammonium salt-73, 0-cymene-5-ol and encapsulated salicylic acid in the present invention have a synergistic technical effect in inhibiting Propionibacterium acnes.

[0113] Test Example 4

[0114] Anti-inflammatory test

[0115] Test method: RAW264.7 cells with good morphology in the logarithmic growth phase were selected and inoculated into 24-well plates and incubated in an incubator for 24 hours. A blank control group, an LPS-induced stimulation group, a positive control group (dexamethasone, DEX, concentration of 0.01%) and a sample group (concentration of 0.1%) were set up and incubated in a 37°C, 5% CO2 incubator for 2 hours. Except for the blank control group, LPS was added to each well and incubated in an incubator for 24 hours. The cell supernatant was tested according to the instructions of the ELISA kit and the nitric oxide detection kit, and the contents of TNF-α, IL-6 and NO in the collected cell supernatant were detected, and the inhibition rates were calculated, respectively. The results are shown in Table 4.

[0116] Table 4

[0117]

[0118]

[0119] It can be seen from the test results in Table 4 that the acne-removing essence provided by the present invention has excellent anti-inflammatory effects, and through the comparison between Application Example 1 and Comparative Application Examples 7-9, it can be seen that niacinamide, β-glucan and oat kernel extract in the present invention have synergistic technical effects in anti-inflammatory effects; through the comparison between Application Example 1 and Comparative Application Example 10, it can be seen that osmanthus extract has excellent anti-inflammatory effects, and when it is not added, the anti-inflammatory effect is weakened.

[0120] Test Example 5

[0121] Acne treatment effect evaluation

[0122] 130 female volunteers aged 25-50 with acne skin were selected and randomly divided into 13 groups, with 10 volunteers in each group. They were asked to use the products once every night after facial cleansing for 30 consecutive days. The other basic skin care products used within 30 days were the same. The volunteers evaluated the acne repair effects of the products provided in the corresponding application examples 1-3 and comparative application examples 1-10. The scoring standards and grades were: 0 points for no acne removal effect; greater than 0 points and less than or equal to 3 points for slight acne removal effect; greater than 3 points and less than or equal to 5 points for obvious acne removal effect. The average value was taken, and the results are shown in Table 5.

[0123] Table 5

[0124]

[0125]

[0126] It can be seen from the test results in Table 5 that the acne-removing essence provided by the present invention can inhibit the formation of acne from multiple aspects such as oil control, anti-inflammatory, antibacterial, and pore unclogging, and fully achieve the purpose of acne removal, and the acne-removing effect is evaluated to be outstanding.

[0127] Test Example 6

[0128] Safety Testing

[0129] Test method: Refer to the "Cosmetic Hygiene Standards" for human skin patch test. 30 volunteers aged 18-60 who are healthy and have no allergic diseases are selected as test subjects. The test subjects are divided into 3 groups, each with 10 people. The products provided in Examples 1-3 are tested. No other skin care products can be used during the test. A patch tester with an area of ​​6mm×6mm is selected, and the test substance is placed in the small chamber of the patch tester. The dosage is 0.025g. The patch tester with the test substance is applied to the back of the subject with a low-allergenic tape, and lightly pressed with the palm of the hand to evenly apply it to the skin for 24 hours. 30 minutes after removing the test substance patch tester (after the indentation disappears), 24 hours and 48 hours respectively. Observe the skin reaction according to the standards shown in the table below and record the observation results.

[0130] Rating Skin reactions 0 Negative reaction 1 Suspicious reaction, only slight erythema 2 Erythema, infiltration, edema, and papules may be present 3 Erythema, infiltration, edema, papules, prolapse; reactions may extend beyond the test area 4 Obvious erythema, severe infiltration, edema, confluent herpes; reaction beyond the test area

[0131] The test results show that the acne-removing essence provided by the present invention is very mild and non-irritating to the skin.

[0132] The applicant declares that the above is only a specific implementation mode of the present invention, but the protection scope of the present invention is not limited thereto. Those skilled in the art should understand that any changes or substitutions that can be easily thought of by those skilled in the art within the technical scope disclosed by the present invention are within the protection scope and disclosure scope of the present invention.

Claims

1. An anti-acne composition, characterized in that: The anti-acne composition comprises osmanthus extract, zinc pyrrolidone carboxylate, encapsulated salicylic acid, quaternary ammonium salt-73, 0-cymene-5-ol, oat beta-glucan, niacinamide and oat kernel extract.

2. The anti-acne composition according to claim 1, characterized in that: The anti-acne composition comprises, by weight, 80-100 parts of osmanthus extract, 0.5-5 parts of zinc pyrrolidone carboxylate, 0.5-5 parts of encapsulated salicylic acid, 0.00125-0.0035 parts of quaternary ammonium salt-73, 0.0275-0.065 parts of 0-cymene-5-ol, 1-5 parts of oat beta-glucan, 2-10 parts of niacinamide and 0.1-0.5 parts of oat kernel extract.

3. Use of the anti-acne composition according to claim 1 or 2 in the preparation of cosmetics.

4. The use according to claim 3, characterized in that: The mass fraction of the anti-acne composition in the cosmetic is 50-95%.

5. The use according to claim 3 or 4, characterized in that: The cosmetics include facial masks, lotions, toners, creams, essences, make-up removers or cleansers.

6. An anti-acne essence, characterized in that: The anti-acne essence comprises a thickener, a moisturizer, a pH regulator and a skin conditioner; the skin conditioner comprises the anti-acne composition according to claim 1 or 2.

7. The anti-acne essence according to claim 6, characterized in that: The anti-acne essence comprises, by weight percentage, 0.1-1% of a thickener, 5-15% of a moisturizer, 0.1-1% of a pH regulator and 70-95% of a skin conditioner.

8. The anti-acne essence according to claim 6 or 7, characterized in that: The thickener includes any one or a combination of at least two of hydroxyethyl cellulose, hydroxypropyl starch phosphate, sodium alginate, polyacrylamide or xanthan gum; Preferably, the moisturizing agent includes any one or a combination of at least two of sodium hyaluronate, trehalose, 1,2-pentanediol, 1,2-hexanediol, dipropylene glycol, 1,2-propylene glycol, 1,3-butylene glycol or caprylyl glycol; Preferably, the pH adjuster comprises sodium citrate.

9. A method for preparing the anti-acne essence according to any one of claims 6 to 8, characterized in that: The preparation method comprises the following steps: The thickener, moisturizer, pH regulator and osmanthus extract, zinc pyrrolidone carboxylate, encapsulated salicylic acid and niacinamide in the skin conditioner are mixed, heated and stirred, and the system is cooled after being dissolved, and quaternary ammonium salt-73, 0-cymene-5-ol, oat β-glucan and oat kernel extract in the skin conditioner are added to obtain the acne-removing essence.

10. The preparation method according to claim 9, characterized in that: The heating is to a temperature of 70-85°C; Preferably, the temperature is lowered to 40-50°C.

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