Traditional Chinese medicine composition for removing residual poison after rash and preventing and treating complications after rash

Through a composition containing a variety of traditional Chinese medicine ingredients, the problems of post-measle residual toxicity removal and complication prevention and treatment are solved, and the effects of effectively removing post-erasy residual toxicity, reducing the probability of pneumonia and shortening the treatment cycle are achieved.

CN119564787APending Publication Date: 2025-03-07JILIN CHILDRENS HOSPITAL
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Patent Information

Application Number
CN202411778487.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-05
Publication Date
2025-03-07
Patent Text Reader

Abstract

The invention relates to a traditional Chinese medicine composition for removing residual poison after rash and preventing and treating complications after rash. The traditional Chinese medicine composition is prepared from 50-80 g of indigo naturalis, 50-80 g of Sichuan notopterygium root, 50-80 g of coptis chinensis, 10-20 g of cinnabar, 50-80 g of bunge corydalis herb, 50-80 g of bulbus fritillariae cirrhosae, 50-80 g of frankincense, 2-5 g of pearl, 40-50 g of liquorice, 50-80 g of chrysanthemum, 10-30 g of antelope silk, 100-120 g of scutellaria baicalensis, 10-15 g of realgar, 10-15 g of borneol, 100-120 g of peach kernel, 150-200 g of honeysuckle, 10-30 g of hawksbill, 40-50 g of amber, 2-5 g of calculus bovis factitius, 50-80 g of myrrh and 100-120 g of radix scrophulariae. The traditional Chinese medicine composition has the effects of clearing away heat and toxic materials, resisting bacteria and diminishing inflammation, cooling blood and removing freckles, clearing away heart fire and tranquilizing mind, moistening lung and reducing phlegm, and relieving cough and asthma, can effectively remove residual poison after rash, reduces the probability of pneumonia, and meanwhile eliminates hyperpigmentation after rash.
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Description

Technical Field

[0001] The invention relates to the field of medicine, and more particularly to a traditional Chinese medicine composition for removing residual toxins after rash and preventing and treating complications after rash. Background Art

[0002] Measles is one of the most common acute respiratory infectious diseases in children. It is highly contagious. The measles virus belongs to paramyxovirus and is transmitted through respiratory secretion droplets. Clinically, it is characterized by fever, upper respiratory tract inflammation, conjunctivitis, and red maculopapular rashes on the skin and measles mucosal spots on the buccal mucosa. After the rash subsides, pigmentation is left, accompanied by bran-like desquamation. It is often complicated by respiratory diseases such as laryngobronchitis and pneumonia; among them, measles pneumonia is the main cause of death caused by measles. The existing treatment methods mainly include giving antiviral (ribavirin) and heat-clearing and detoxifying (Xiyanping) drugs. For children with laryngobronchitis and pneumonia, cough and expectorant, antibacterial drugs, etc. are given at the same time. Although most children can be cured, the treatment cycle is long, which greatly reduces the quality of life of children. If timely intervention can be made in the early stage of measles to prevent complications, the pain of children can be alleviated and the mortality rate of children with measles and severe pneumonia can be reduced. However, there is currently no Chinese medicine composition for removing the residual toxins after the rash and preventing and treating the complications after the rash. Summary of the invention

[0003] The object of the present invention is to provide a traditional Chinese medicine composition for removing residual toxins after rash and preventing and treating complications after rash. The traditional Chinese medicine composition has the functions of clearing away heat and detoxifying, resisting bacteria and reducing inflammation, cooling blood and removing spots, clearing the heart and calming the mind, moistening the lungs and resolving phlegm, and relieving cough and asthma. It can effectively remove residual toxins after rash, reduce the probability of pneumonia, and eliminate pigmentation after rash.

[0004] To achieve the above object, the present invention adopts the following technical solution:

[0005] A traditional Chinese medicine composition for removing residual toxins after rash and preventing and treating complications after rash, the traditional Chinese medicine composition consists of 50-80g of Indigo Naturalis, 50-80g of Rhizoma Chuanxiong, 50-80g of Rhizoma Coptidis, 10-20g of Cinnabaris, 50-80g of Rhizoma Cyperi, 50-80g of Fritillariae Cirrhosae, 50-80g of Olibanum, 2-5g of Pearl, 40-50g of Licorice, 50-80g of Chrysanthemum, 10-30g of Antelope Silk, 100-120g of Scutellaria Baicalensis, 10-15g of Realgar, 10-15g of Borneolum Syntheticum, 100-120g of Peach Kernel, 150-200g of Honeysuckle, 10-30g of Hawksbill Turtle, 40-50g of Amber, 2-5g of Artificial Bezoar, 50-80g of Myrrh and 100-120g of Scrophulariae.

[0006] As the preferred embodiment of the present invention, the Chinese medicine composition is composed of 60g of Indigo Naturalis, 60g of Rhizoma Chuanxiong, 60g of Coptis Chinensis, 10g of Cinnabar, 60g of Herba Phytophthorae, 60g of Fritillariae Chuanxiong, 60g of Frankincense, 2.5g of Pearl, 40g of Licorice, 60g of Chrysanthemum, 15g of Antelope Silk, 100g of Scutellaria Baicalensis, 10g of Realgar, 12g of Borneol, 120g of Peach Kernel, 200g of Honeysuckle, 15g of Hawksbill Turtle, 40g of Amber, 2.5g of Artificial Bezoar, 60g of Myrrh and 100g of Scrophulariae.

[0007] The present invention also provides Babao powder for removing residual toxins after rash and preventing and treating complications after rash. The preparation method of Babao powder is as follows: the pearls and cinnabar in the above-mentioned traditional Chinese medicine composition are ground into extremely fine powder respectively, the indigo and borneol are ground into fine powder respectively, the antelope silk and other medicinal flavors are crushed into fine powder, and the powder is mixed with the above-mentioned four kinds of medicinal powders, and the powder is passed through a 100-mesh sieve and packaged to obtain the powder.

[0008] Advantages and beneficial effects of the present invention:

[0009] (1) The Chinese medicine composition provided by the present invention has the effects of clearing away heat and detoxifying, resisting bacteria and relieving inflammation, cooling blood and removing spots, clearing the heart and calming the mind, moistening the lungs and resolving phlegm, and relieving cough and asthma. Among them, Indigo, Antelope Silk, Coptis chinensis, Herba Lycoris, Chrysanthemum, Baical Scutellariae, and Flos Lonicerae are bitter and cold in nature and can clear away heat and cool blood, purge fire and detoxify. Antelope Silk and Indigo are selected to be compatible with other herbs to enhance the effects of clearing away heat and detoxifying, cooling blood and removing spots, and can also calm convulsions. When combined with amber, cinnabar and other herbs, it can effectively prevent high fever convulsions in children with measles. Fritillaria cirrhosa is bitter, sweet and slightly cold; Scrophularia ningpoensis is bitter, sweet, salty and cold; Peach kernel is bitter, sweet and neutral. The three herbs can clear away heat and moisten the lungs, resolve phlegm and relieve cough. Among them, Peach kernel can also promote blood circulation and remove blood stasis, relieve cough and asthma, and can enhance the effects of removing phlegm and relieving cough when combined with other herbs. Realgar is pungent and warm, can dry dampness and remove phlegm, relieve The bitter and cold nature of the above-mentioned medicines can further enhance the effect of removing phlegm; cinnabar can clear away heat and detoxify, remove blood stasis and stop bleeding, and calm the nerves; pearl can extinguish wind and clear heat, calm the heart and calm the nerves; amber can calm the nerves, promote blood circulation and remove blood stasis; hawksbill turtle can clear away heat and detoxify, soothe the liver and calm the nerves; borneol is pungent, bitter and slightly cold, and can clear away heat and detoxify, calm the nerves and calm the nerves; the above-mentioned five medicines can play the effects of clearing the heart and calming the nerves, calming the nerves and detoxifying, and can treat high fever caused by intense heat and toxicity, and even coma and convulsions; Sichuan Qiang is pungent and warm, dispersing, and has anti-inflammatory and analgesic effects; frankincense and myrrh can promote blood circulation and qi, and have anti-inflammatory and analgesic effects; the three medicines are all pungent and warm in nature, and can regulate the circulation of qi and blood. At the same time, the three medicines have antibacterial, anti-inflammatory and analgesic effects; artificial bezoar can be used in combination with the above-mentioned medicines to enhance the effects of clearing heat and detoxifying, removing phlegm and relieving cough, and antibacterial, calming the nerves and calming the nerves; licorice is sweet and flat, can remove phlegm and relieve cough, and harmonize the various medicines.

[0010] (2) The Chinese medicine composition provided by the present invention can effectively remove residual toxins after rash, and it can regulate qi and blood and has antibacterial and anti-inflammatory functions. It can treat complications related to secondary bacterial infection, play a good preventive role, and reduce the probability of measles children developing pneumonia.

[0011] (3) The Chinese medicine composition provided by the present invention also has a good therapeutic effect on children with measles and pneumonia. It can effectively relieve the symptoms of children and avoid convulsions caused by high fever. At the same time, it can shorten the treatment cycle, promote early recovery of children, and eliminate post-rash pigmentation. DETAILED DESCRIPTION

[0012] The present invention discloses a Chinese medicine composition for removing residual toxins after rash and eliminating complications after rash. Those skilled in the art can refer to the contents of this article and appropriately improve the component parameters or process parameters to achieve the above. It should be particularly noted that all similar substitutions and modifications are obvious to those skilled in the art and are deemed to be included in the scope of protection of the present invention.

[0013] Example 1

[0014] The present embodiment provides a traditional Chinese medicine composition for clearing residual toxins after rash and eliminating complications after rash, the traditional Chinese medicine composition is composed of 60g of Indigo Naturalis, 60g of Rhizoma Chuanxiong, 60g of Coptis chinensis, 10g of Cinnabar, 60g of Herba Phytophthorae, 60g of Fritillariae Cirrhosae, 60g of Frankincense, 2.5g of Pearl, 40g of Licorice, 60g of Chrysanthemum, 15g of Antelope Silk, 100g of Scutellaria Baicalensis, 10g of Realgar, 12g of Borneol, 120g of Peach Kernel, 200g of Honeysuckle, 15g of Hawksbill Turtle, 40g of Amber, 2.5g of Artificial Bezoar, 60g of Myrrh, and 100g of Scrophulariae.

[0015] The Chinese medicine composition provided in this embodiment can be made into an oral preparation when actually used; the oral preparation includes powders, granules, tablets, capsules, decoctions or pills, etc. Among the above dosage forms, powders have the advantage of being simple to prepare, so powders are preferred.

[0016] Example 2

[0017] The present embodiment provides a Babao powder for removing residual toxins after rash and eliminating complications after rash. The preparation method of the Babao powder is as follows: grind the pearls and cinnabar in the Chinese medicine composition of Example 1 into extremely fine powders, grind the indigo and borneol into fine powders, crush the antelope silk and other medicinal ingredients into fine powders, mix and grind with the above four medicinal powders, pass through a 100-mesh sieve, and package to obtain the powder.

[0018] The Babao powder provided by the present invention has the functions of clearing away heat and detoxifying, resisting bacteria and reducing inflammation, cooling blood and removing spots, clearing the heart and calming the mind, moistening the lungs and resolving phlegm, and relieving cough and asthma. This prescription has been used in Jilin Children's Hospital for many years. The following is an illustration of the therapeutic effect of the Babao powder described in Example 2 of the present invention through clinical data, and the specific situation is as follows:

[0019] Clinical Data

[0020] 1. General Information

[0021] A total of 62 children aged 0 to 12 years old who were admitted to Jilin Children's Hospital from May 2020 to June 2021 were collected. There were 40 males and 22 females. All children had symptoms such as fever, rash, and cough. Fifty cases had a fever above 39°C, and 12 cases had a fever between 37.5 and 39°C. Children with measles were divided into two groups according to whether the patients had pneumonia; 48 cases had pneumonia and 14 cases did not have pneumonia. Inclusion criteria: ① Meet the diagnostic criteria for measles (WS296-2017); ② All children with measles pneumonia were diagnosed in accordance with the "Guidelines for the Management of Community-Acquired Pneumonia in Children in 2013". Exclusion criteria: children with diseases such as liver and kidney damage.

[0022] 2. Treatment Methods

[0023] All children were given the same treatment after admission, and were given the Babao Powder of Example 2 (0.35-0.5 g once per year old, 2-3 times a day, those under 1 year old are calculated as one year old, those over 1 year old are calculated as 2 years old, those over 2 years old are calculated as 3 years old, and so on; the specific usage and dosage are: under 1 year old: 0.5 g once, twice a day; 2 to 3 years old: 1 g once, twice a day; 4 to 6 years old, 2 g once, twice a day; 7 to 10 years old, 3.5 g once, twice a day; over 10 years old, 5 g once, twice a day), while receiving supportive treatment such as oxygen inhalation and nebulization, those with combined bacterial infection were given antibiotic anti-infection treatment, and those with combined Mycoplasma pneumoniae infection were given azithromycin treatment.

[0024] 3. Results

[0025] Table 1 Comparison of disappearance time of papules and body temperature recovery time between the two groups ( d)

[0026] Group Time for papules to disappear (d) Body temperature recovery time (d) Pneumonia group 4.35±0.23 3.42±0.33 Non-pneumonia group 3.46±0.18 2.15±0.23

[0027] In addition, none of the above-mentioned children experienced high fever convulsions during the treatment, and all were discharged after being cured, with a cure rate of 100%. Among them, the average hospitalization days for the pneumonia group was 6.75 days, and the average hospitalization days for the non-pneumonia group was 3.71, which greatly shortened the treatment cycle.

[0028] The above description is a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A Chinese medicine composition for removing residual toxins after rash and preventing and treating complications after rash, characterized in that: The traditional Chinese medicine composition consists of 50-80g of Indigo Naturalis, 50-80g of Rhizoma Chuanxiong, 50-80g of Rhizoma Coptidis, 10-20g of Cinnabaris, 50-80g of Herba Phytophthorae, 50-80g of Fritillariae Cirrhosae, 50-80g of Frankincense, 2-5g of Pearl, 40-50g of Licorice, 50-80g of Chrysanthemum, 10-30g of Antelope Silk, 100-120g of Scutellaria Baicalensis, 10-15g of Realgar, 10-15g of Borneolum Syntheticum, 100-120g of Peach Kernel, 150-200g of Honeysuckle, 10-30g of Hawksbill Turtle, 40-50g of Amber, 2-5g of Artificial Bezoar, 50-80g of Myrrh and 100-120g of Scrophulariae.

2. A Chinese medicine composition for removing residual toxins after rash and preventing and treating complications after rash according to claim 1, characterized in that: The traditional Chinese medicine composition consists of 60g of Indigo Naturalis, 60g of Rhizoma Chuanxiong, 60g of Coptis Chinensis, 10g of Cinnabar, 60g of Herba Phytophthorae, 60g of Fritillariae Cirrhosae, 60g of Frankincense, 2.5g of Pearl, 40g of Licorice, 60g of Chrysanthemum, 15g of Antelope Silk, 100g of Scutellaria Baicalensis, 10g of Realgar, 12g of Borneol, 120g of Peach Kernel, 200g of Honeysuckle, 15g of Hawksbill Turtle, 40g of Amber, 2.5g of Artificial Bezoar, 60g of Myrrh and 100g of Scrophulariae.

3. A Babao powder for removing residual toxins after rash and preventing and treating complications after rash, characterized in that: The preparation method of Babaosan is as follows: grind the pearls and cinnabar in the Chinese medicine composition of claim 1 or 2 into extremely fine powder respectively, grind the indigo and borneol into fine powder respectively, crush the antelope silk and other medicinal ingredients into fine powder, mix and grind with the above four medicinal powders, pass through a 100-mesh sieve, and package to obtain the Babaosan.