A composition for preventing chicken necrotic enteritis and use thereof

Abstract

This application discloses a composition for combating necrotizing enteritis in chickens and its application. The active ingredients in the composition, by weight, consist of 5 parts paeonol, 5 parts farnesol, and 1 part soy saponin. This composition can also be formulated into oral liquids, tablets, granules, or powders using paeonol, farnesol, and soy saponin as active ingredients and excipients, with a dosage of 100-1000 mg / kg body weight; or the composition can be directly added to feed at a dosage of 0.1%-1% of the total weight of the chicken feed. The composition formed by paeonol, farnesol, and soy saponin provided in this application, as a drug, has high safety and no toxic side effects. It can effectively inhibit the proliferation of chicken-derived pathogens such as Clostridium perfringens, Salmonella, and Escherichia coli, effectively increase the antibody titer of Newcastle disease vaccine, and alleviate the reduction in chicken production performance, the increase in pro-inflammatory cytokines, and the impairment of intestinal absorption and barrier function caused by coccidiosis and necrotizing enteritis.

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