Guide wire to guide catheter

Abstract

The application relates to a guide wire joint guide tube which comprises a control handle, a main pipe and a flared control assembly, the main pipe comprises a main body section and a flared section, the proximal end of the main body section is connected to the control handle, the distal end of the main body section is connected to the proximal end of the flared section, a wire storage hole is arranged in the pipe wall of the main pipe, the wire storage hole extends to the elastic outer layer of the flared section; the flared control assembly comprises a passive wire, a driving wire, a traction wire and a rotating mechanism, the distal end of the passive wire is arranged to extend to the elastic outer layer along the wire storage hole, the passive wire is fixed to the inner wall of the elastic outer layer where the wire storage hole is located, the distal end of the driving wire is connected to the distal end of the passive wire, and the rotating mechanism is arranged in the control handle and is used for traction of the driving wire through the traction wire. The guide wire joint guide tube of the application utilizes the rotating knob mechanism to traction the driving wire through the traction wire, so that the driving traction wire drives the passive wire to exert a proximal end-directed pulling force on the flared section, the flared angle of the flared section is adjusted, the reverse threading success rate is improved, and the reverse threading time is shortened.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical devices, in particular to a guide wire connector guide tube. BACKGROUND

[0002] In the process of treating lower extremity arteriosclerosis obliterans using minimally invasive intervention method, a guide wire needs to be first used to pass through the lesion, and then a guide wire guide sheath is used to guide the guide sheath to the target lesion, so that the guide sheath provides a channel and protection for other instruments, and finally other instruments are inserted to perform treatment.

[0003] However, the lower extremity blood vessels often have severe calcification and plaques, and the guide wire cannot pass through the lesion smoothly. Doctors usually choose to use reverse threading, that is, to increase the puncture point below the knee artery, use the guide wire to pass through the lesion upwards, and connect with the downward guide wire or sheath to increase the technical success rate of passing through the target lesion.

[0004] However, the guide wire connection in reverse threading is a long process, which tests the doctor's skills and patience. Figure 1 As shown in the figure, when the guide wire 2 is inserted below the knee using reverse threading, the guide wire 2 often cannot be aligned with the center of the guide tube 1, resulting in deviation of the connection, and slight deviation of the relatively connected guide wire 2 and guide tube 1 will result in failure to complete the connection. SUMMARY

[0005] Therefore, a guide wire connector guide tube is provided to solve the problem of how to improve the success rate and efficiency of guide wire reverse threading.

[0006] The present application provides a guide wire connector guide tube, comprising:

[0007] a control handle;

[0008] a main tube comprising a main body segment and a flared segment, a proximal end of the main body segment being connected to the control handle, a distal end of the main body segment being connected to a proximal end of the flared segment, a tube wall of the main tube being provided with a wire storage hole, the flared segment comprising an elastic outer layer, the wire storage hole extending to the elastic outer layer;

[0009] a flared control assembly comprising a passive wire, an active wire, a traction wire and a rotating mechanism, a distal end of the passive wire being provided along the wire storage hole to the elastic outer layer, the passive wire being fixed to an inner wall of the elastic outer layer where the wire storage hole is located, a distal end of the active wire being connected to a distal end of the passive wire, the rotating mechanism being provided in the control handle and being used to pull the active wire through the traction wire.

[0010] In one embodiment, a plurality of wire storage holes are provided in the tube wall of the main tube, each of the wire storage holes is respectively provided with the active wire and the passive wire, a plurality of the active wires are wound around one and connected to one end of the traction wire, the other end of the traction wire is connected to the rotating mechanism.

[0011] In one of the embodiments, the flared angle of the flared section is 0°-90°, and / or the elastic outer layer comprises a thermoplastic elastomer material.

[0012] In one of the embodiments, the rotating mechanism comprises a driving knob, a fixed knob, a passive knob and a movable screw rod, the driving knob is coaxially connected with the fixed knob and can rotate relative to the fixed knob, the driving knob is fixed with the passive knob, one side of the driving knob and the fixed knob has a through hole for placing the movable screw rod and allowing the movable screw rod to move in the axial direction, the movable screw rod is threadedly connected with the passive knob, and the distal end of the movable screw rod is connected with the traction wire.

[0013] In one of the embodiments, the guide wire guide tube further comprises a pressure control assembly for adjusting the bending degree of the main body section according to the pressure change of the main body section in the blood vessel.

[0014] In one of the embodiments, the pressure control assembly comprises a liquid crystal dielectric elastomer, a current amplifier and a pressure sensor, the liquid crystal dielectric elastomer, the current amplifier and the pressure sensor are all embedded in the wall of the main body section, the pressure sensor is used to generate a current signal when the main body section is extruded by the blood flow in the blood vessel, the current amplifier is used to amplify the current signal from the pressure sensor, so that the liquid crystal dielectric elastomer deforms and bends under the action of the current.

[0015] In one of the embodiments, the number of pressure sensors and the number of wire storage holes are both multiple, and the pressure sensors are arranged one by one corresponding to the wire storage holes; and / or the pressure sensor comprises a resistance strain gage.

[0016] In one of the embodiments, the liquid crystal dielectric elastomer, the current amplifier and the pressure sensor are connected in series, when the current amplified by the current amplifier is greater than or equal to a preset value, the liquid crystal dielectric elastomer deforms and returns to the bent state; when the current amplified by the current amplifier is less than the preset value, the liquid crystal dielectric elastomer remains in the straightened state.

[0017] In one of the embodiments, the liquid crystal dielectric elastomer is of a light response type, the wall of the main body section is further provided with an annular light belt, the liquid crystal dielectric elastomer is connected to the outer side of the annular light belt, the annular light belt is connected in series with the current amplifier and the pressure sensor, so that the current amplified by the current amplifier flows through the annular light belt, the annular light belt can emit ultraviolet light and visible light, under the irradiation of ultraviolet light, the liquid crystal dielectric elastomer deforms and returns to the bent state; under the irradiation of visible light or heating, the liquid crystal dielectric elastomer remains in the straightened state.

[0018] In one embodiment, the annular light strip is connected in series with a switch, which is provided on the control handle, and the switch is used to select whether the annular light strip emits ultraviolet light or visible light; or the color of the light emitted by the annular light strip can be adjusted according to the current size, when the current is less than a threshold value, the annular light strip emits visible light, and when the current is greater than or equal to the threshold value, the annular light strip changes from visible light to ultraviolet light.

[0019] The above guide wire connector guide tube, because the main tube wall is provided with a wire storage hole, the flared section includes an elastic outer layer, the wire storage hole extends to the elastic outer layer, and the passive wire is fixed to the inner wall of the elastic outer layer, so that when the guide wire needs to be connected, the knob mechanism of the control handle is adjusted, the active wire is pulled by the traction wire, the active traction wire drives the passive wire to exert a proximal pulling force on the flared section, the flared angle of the flared section can be adjusted, the reverse threading success rate is improved, and the reverse threading time is shortened. BRIEF DESCRIPTION OF DRAWINGS

[0020] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the drawings needed in the embodiments or prior art description will be briefly introduced below. Obviously, the drawings in the following description are only some embodiments of the present application, and those skilled in the art can also obtain drawings of other embodiments according to these drawings without creative labor.

[0021] Figure 1 A schematic diagram of the guide wire deviating from the catheter during reverse threading operation in the related art.

[0022] Figure 2 A structure schematic diagram of the guide wire connector guide tube in Embodiment 1 of the present application, when the flared section of the main tube is not expanded.

[0023] Figure 3 A structure schematic diagram of the guide wire connector guide tube in Embodiment 1 of the present application, when the flared section of the main tube is expanded.

[0024] Figure 4 A partial structure exploded schematic diagram of the guide wire connector guide tube in Embodiment 1 of the present application.

[0025] Figure 5 A Figure 4 A cross-sectional structure schematic diagram of the guide wire connector guide tube along the A-A line.

[0026] Figure 6 A Figure 5 A cross-sectional structure schematic diagram along the C-C line.

[0027] Figure 7 A Figure 4The cross-sectional structure of the flared section along the B-B line in the guide wire connector guide tube.

[0028] Figure 8 The setting structure of the passive wire, the active wire and the traction wire in the main tube of the guide wire connector guide tube of the embodiment 1 of the present application.

[0029] Figure 9 For Figure 8 The structure of the main tube of the guide wire connector guide tube, which makes the flared section expand when the traction wire exerts the pulling force F on the active wire towards the proximal end.

[0030] Figure 10 The schematic diagram of the guide wire connector guide tube of the embodiment 1 of the present application receiving the reverse guide wire by the expanded flared section.

[0031] Figure 11 The circuit diagram of the pressure control assembly in the guide wire connector guide tube of the embodiment 1 of the present application.

[0032] Figure 12 The principle of the liquid crystal dielectric elastomer deforming with the change of the current in the guide wire connector guide tube of the embodiment 1.

[0033] Figure 13 The structure of the liquid crystal dielectric elastomer in the main tube of the guide wire connector guide tube of the embodiment 2 and the embodiment 3 of the present application, which is arranged outside the annular lamp belt.

[0034] Figure 14 The light source control circuit diagram of the pressure control assembly in the guide wire connector guide tube of the embodiment 2 and the embodiment 3 of the present application.

[0035] Figure 15 The principle of the liquid crystal dielectric elastomer deforming under the illumination of different wavelengths in the guide wire connector guide tube of the embodiment 2 and the embodiment 3 of the present application.

[0036] Reference signs:

[0037] 1, catheter; 2, guidewire; 100, guidewire introducer catheter; 101, stress dispersion tube; 102, luer fitting; 10, control handle; 11, handle housing; 111, first housing; 112, second housing; 12, hollow cover; 20, main tube; 21, main body section; 211, polymer outer layer; 22, flared section; 221, elastic outer layer; 23, wire storage hole; 30, flared control assembly; 31, passive wire; 32, active wire; 33, traction wire; 34, rotation mechanism; 341, active knob; 341a, groove; 342, fixed knob; 343, passive knob; 344, movable screw; 40, pressure control assembly; 41, liquid crystal dielectric elastomer; 41a, crosslinking point; 41b, liquid crystal unit; 42, current amplifier; 43, pressure sensor; 44, circuit board; 45, power supply; 46, switch; 47, wire; 48, LED screen; 49, ring-shaped light strip. DETAILED DESCRIPTION

[0038] In order to make the above objectives, features and advantages of the present application more apparent, the specific embodiments of the present application will be described in detail below with reference to the accompanying drawings. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present application. It will be apparent, however, to one skilled in the art that the present application can be practiced in a variety of ways beyond the specific embodiments described herein without departing from the spirit of the present application, and it is intended that the present application cover all such modifications and changes within its scope.

[0039] It should be noted that when an element is referred to as being "on" or "set on" another element, it can be directly on the other element or there can be an intervening element. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or there can be an intervening element.

[0040] The terms "vertical", "horizontal", "upper", "lower", "left", "right", and similar terms are used for explanation only and are not intended to be limiting.

[0041] It should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are used only for convenience of description and simplification of the description, and are not intended to indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be construed as limiting the present application.

[0042] It should be noted that "distal" and "proximal" are used as orientation words, which are common terms in the field of interventional medical devices, where "distal" means the end far from the operator (such as a doctor) during the operation, and "proximal" means the end close to the operator during the operation. Axial refers to the direction in which the central axis of the medical device extends; radial refers to the direction perpendicular to the axial direction.

[0043] Embodiment 1

[0044] In combination Figures 2 to 4 As shown in the drawings, the embodiment of the present application provides a guide wire connector guide tube 100, which comprises a control handle 10, a main tube 20 and a flared control assembly 30. The proximal end of the main tube 20 is connected to the control handle 10. The control handle 10 is used to operate the flared control assembly 30 at the proximal end of the main tube 20, so that the flared control assembly 30 adjusts the opening size of the distal end of the main tube 20.

[0045] For ease of understanding, the pipe section of the distal end of the main tube 20 which can adjust the opening size is referred to as "flared section 22". Specifically, the main tube 20 comprises a main body section 21 and a flared section 22. The proximal end of the main body section 21 is connected to the control handle 10, and the distal end of the main body section 21 is connected to the proximal end of the flared section 22. In some embodiments, the flared section 22 is welded to the main body section 21 by heat staking, so that the main body section 21 and the flared section 22 are integrated as a whole, ensuring the structural stability of the main tube 20 as a whole.

[0046] In combination Figures 5 to 7 As shown in the drawings, the main tube 20 is provided with a wire storage hole 23 in the pipe wall, which extends along the length direction of the main tube 20 and penetrates through the main body section 21 to the flared section 22.

[0047] The number of wire storage holes 23 can be 1, or 2 or more. When the number of wire storage holes 23 is 2 or more, these wire storage holes 23 are uniformly distributed along the circumferential direction of the main tube 20.

[0048] For the pipe material of the main tube 20 with the wire storage hole 23, it can be obtained by extrusion molding through an extruder, or it can be made by multi-layer and multi-section heat staking of the guide tube 1 by reflow soldering. The manufacturing process of the main body section 21 is not limited here.

[0049] In combination Figure 5 And Figure 6 As shown in the drawings, the pipe wall of the main body section 21 comprises a polymer outer layer 211. The polymer outer layer 211 is an insulating material, and at the same time has a certain flexibility and rigidity, which helps the guide tube 1 to reach the lesion site. The material of the polymer outer layer 211 can be nylon or Pebax, etc.

[0050] In combination Figure 7As shown, the flared section 22 comprises an elastic outer layer 221, and the filament storage hole 23 extends to the elastic outer layer 221.

[0051] In combination Figure 4 and Figure 5 As shown, the flared control assembly 30 comprises a passive filament 31, an active filament 32, a traction filament 33 and a rotating mechanism 34.

[0052] In combination Figure 6 and Figure 8 As shown, the distal end of the passive filament 31 is arranged along the filament storage hole 23 to the elastic outer layer 221, and the passive filament 31 is fixed to the inner wall of the elastic outer layer 221. Thus, when the passive filament 31 is subjected to a proximal pulling force, the elastic outer layer 221 will be elastically deformed under the traction of the passive filament 31, thereby adjusting the opening angle of the flared section 22, i.e. the flared angle.

[0053] The connection between the passive filament 31 and the inner wall of the filament storage hole 23 includes but is not limited to hot melt connection or adhesive connection.

[0054] The distal end of the passive filament 31 is connected to the distal end of the active filament 32, and the connection mode includes but is not limited to welding. The plurality of active filaments 32 are arranged along the filament storage hole 23 from the main pipe 20 to the control handle 10 to be connected to the rotating mechanism 34.

[0055] The rotating mechanism 34 is arranged in the control handle 10 and is used to pull the active filament 32 through the operation of the traction filament 33, thereby adjusting the flared angle of the flared section 22.

[0056] It should be noted that in the embodiment in which the filament storage hole 23 is multiple, each filament storage hole 23 is respectively provided with an active filament 32 and a passive filament 31. That is, the number of active filaments 32 and passive filaments 31 can be configured to be consistent with the number of filament storage holes 23. For example, the active filament 32 is a plurality of strands, and the plurality of active filaments 32 are wound around one strand and connected to one end of the traction filament 33, and the other end of the traction filament 33 is connected to the rotating mechanism 34 in the control handle 10. Thus, the rotating mechanism 34 in the control handle 10 can be operated to move the active filament 32 along the filament storage hole 23 through the traction filament 33, thereby achieving the effect of controlling the flared angle of the flared section 22. For example, when the control handle 10 is operated to make the traction filament 33 subjected to a proximal pulling force, the traction filament 33 drives the plurality of active filaments 32 to simultaneously retreat proximally relative to the main pipe 20. Since the distal end of the active filament 32 is connected to the passive filament 31, and the passive filament 31 is fixed to the inner wall of the elastic outer layer 221 of the flared section 22, the flared section 22 is subjected to a proximal pulling force of the traction filament 33, and the flared section 22 is in an open state under the action of the pulling force. Understandably, the greater the proximal retreat stroke of the traction filament 33, the greater the opening of the flared section 22.

[0057] In some embodiments, the flare angle of the flare section 22 is 0°-90°. When the flare angle of the flare section 22 is 0°, it can be understood that the flare section 22 has not been expanded. When the flare angle of the flare section 22 is 90°, it can be understood that the flare section 22 has an opening angle of 90°.

[0058] In combination Figure 9 As shown, by operating the control handle 10 to apply a proximal pulling force F to the plurality of active filaments 32 through the traction filaments 33, the flare angle of the flare section 22 can be adjusted so that the flare section 22 changes within the range of 0°-90°, so that the opening angle of the flare section 22 is appropriate. For example, in some embodiments, the flare angle of the flare section 22 is 1°, 5°, 15°, 25°, 35°, 45°, 55°, 65°, 75°, 85°, or 90°. The specific flare angle of the flare section 22 is not limited herein.

[0059] In combination Figure 10 As shown, based on the flare section 22, the flare angle can be adjusted to be appropriate, so that the reverse guide wire 2 is conveniently connected, so that the reverse success rate is improved, and the reverse time is shortened.

[0060] In some embodiments, the plurality of active filaments 32 and the traction filaments 33 can be connected in a welding manner. This welding manner not only facilitates the connection of the active filaments 32 and the traction filaments 33, but also stabilizes the connection.

[0061] The elastic outer layer 221 can be a thermoplastic elastomer material, including but not limited to TPE or TPU, etc. Preferably, the preset position of the elastic outer layer 221 is doped with a developing material for distinguishing the position of the catheter 1 under DSA (Digital Subtraction Angiography, cerebral digital subtraction angiography) imaging. The developing material can be BaSO4, Bi2O3, or W, etc.

[0062] Again referring to Figure 2 and Figure 3 As shown, in some embodiments, the guide wire connection catheter 100 includes a stress diffusion tube 101, which is sleeved on the main tube 20 and is connected to the control handle 10 by adhesion. The main tube 20 is prevented from being bent during use. The material of the stress diffusion tube 101 includes but is not limited to silicone or TPU, etc.

[0063] In some embodiments, the guide wire connection catheter 100 includes a luer connector 102. The luer connector 102 serves as a connection function so as to cooperate with other instruments. The luer connector 102 and the main tube 20 can be connected by adhesion or pre-embedded injection molding. The material of the luer connector 102 includes but is not limited to PC, Pebax, or PP, etc.

[0064] In combination Figure 4 As shown, the control handle 10 comprises a handle shell 11 and a hollow cover 12, which is arranged at the distal end of the handle shell 11.

[0065] The handle shell 11 comprises a first shell 111 and a second shell 112. The first shell 111 and the second shell 112 are shaped to match the outer shape of the luer joint 102 so as to fix the luer joint 102 between the first shell 111 and the second shell 112. The overall shape of the handle shell 11 is ergonomic, thus facilitating the grip feeling when lifting the control handle 10.

[0066] The material of the handle shell 11 includes, but is not limited to, PP, ABS, PC / ABS, etc.

[0067] In combination Figure 4 As shown, the rotating mechanism 34 comprises a driving knob 341, a fixed knob 342, a driven knob 343 and a movable screw rod 344. The driving knob 341 is coaxially connected with the fixed knob 342 and can rotate relative to the fixed knob 342. The driving knob 341 is fixed with the driven knob 343.

[0068] When the driving knob 341 rotates relative to the fixed knob 342, the driven knob 343 rotates together with the driving knob 341 and has the same rotation angle.

[0069] The driving knob 341 and the fixed knob 342 have a through hole on one side, which is used to place the movable screw rod 344 and can move the movable screw rod 344 in the axial direction, so as to realize the movement of the movable screw rod 344 towards the distal end or the proximal end.

[0070] The movable screw rod 344 is threadedly connected with the driven knob 343, and when the driven knob 343 rotates relative to the fixed knob 342, the movable screw rod 344 can be threadedly driven to move in the axial direction. It should be noted that the surface of the movable screw rod 344 has external threads, and the inner wall of the driven knob 343 is provided with internal threads which are closely engaged with the external threads, so that the movable screw rod 344 is threadedly connected with the driven knob 343.

[0071] The distal end of the movable screw rod 344 is connected with the traction wire 33. The distal end of the movable screw rod 344 and the traction wire 33 can be fixed by welding or connected by glue. The connection mode between the movable screw rod 344 and the traction wire 33 is not limited herein.

[0072] When the passive knob 343 is rotated, the movable screw rod 344 is driven to move proximally, so that the movable screw rod 344 drives the traction wire 33 to move proximally, so that the traction wire 33 can be withdrawn proximally through the plurality of active wires 32, and then the passive wire 31 exerts a proximal pulling force on the flared section 22 to adjust the flared angle of the flared section 22.

[0073] The materials of the active knob 341 and the fixed knob 342 can be the same as the material of the handle shell 11. For example, the materials of the active knob 341 and the fixed knob 342 include but are not limited to PP, ABS, PC / ABS structure. In some embodiments, the passive knob 343 can also adopt a material different from the active knob 341. For example, the material of the passive knob 343 includes but is not limited to PEEK or PE.

[0074] The material of the movable screw rod 344 includes but is not limited to PC / ABS, ABS+glass fiber, etc., which is not limited here.

[0075] Continue to combine Figure 4 As shown, in some embodiments, the active knob 341 is provided with a groove 341a, and the hollow cover 12 is connected with the groove 341a on the active knob 341 to provide space for the movement of the traction wire 33.

[0076] The fixed knob 342 can be threadedly connected with the handle shell 11. For example, the first shell 111 and the second shell 112 have a first threaded structure at the distal end, and the proximal end of the fixed knob 342 has a second threaded structure. The first threaded structure is engaged with the second threaded structure, so as to connect the fixed knob 342 to the distal end of the first shell 111 and the second shell 112.

[0077] The connection between the fixed knob 342 and the handle shell 11 is not limited to the threaded connection described above. For example, in some embodiments, the fixed knob 342 can also be connected with the handle shell 11 through a buckle or a screw, etc. The connection between the fixed knob 342 and the handle shell 11 is not limited here.

[0078] Combine Figures 4 to 6 As shown, in some embodiments, the guide wire connector guide tube 100 further comprises a pressure control assembly 40 for adjusting the bending degree of the main body section 21 according to the pressure change of the main body section 21 in the blood vessel, so that the flared section 22 at the distal end of the main body section 21 tends to be in the central position in the blood vessel. Thus, the guide wire 2 can be easily inserted into the main tube 20 from the flared section 22.

[0079] The pressure control assembly 40 includes a liquid crystal dielectric elastomer 41, a current amplifier 42 and a pressure sensor 43. The liquid crystal dielectric elastomer 41, the current amplifier 42 and the pressure sensor 43 are all embedded in the pipe wall of the main body section 21.

[0080] In combination Figure 11 As shown, the liquid crystal dielectric elastomer 41, the current amplifier 42 and the pressure sensor 43 are components of the pressure control assembly 40. These elements form a closed circuit for displaying and controlling the bending of the main body section 21, etc.

[0081] In combination Figure 12 As shown, the liquid crystal dielectric elastomer 41 includes cross-linking points 41a and liquid crystal units 41b. The liquid crystal dielectric elastomer 41 is a high-molecular polymer with shape memory formed after the liquid crystal polymer is properly cross-linked.

[0082] The principle of shape memory of the liquid crystal dielectric elastomer 41 is as follows: in combination Figure 12 As shown, the liquid crystal dielectric elastomer 41 is oriented by external force, i.e. is shaped and straightened, and the orientation is fixed after cooling, and the liquid crystal units 41b are converted into a single-domain state. The liquid crystal dielectric elastomer 41 can be thermally responsive (i.e. returns to deformation upon heating) or light responsive (i.e. returns to deformation upon light). When subjected to different stimuli, such as thermal effect or light effect caused by electric current, the liquid crystal units 41b of the liquid crystal dielectric elastomer 41 will return to a multi-domain state, i.e. deformation recovery.

[0083] The liquid crystal dielectric elastomer 41, the current amplifier 42 and the pressure sensor 43 are connected in series. When the current amplified by the current amplifier 42 is greater than or equal to a preset value, the liquid crystal dielectric elastomer 41 returns to the curved state; when the current amplified by the current amplifier 42 is less than the preset value, the liquid crystal dielectric elastomer 41 remains in the straightened state.

[0084] Suppose Imin is the minimum current value (i.e. the preset value) at which the liquid crystal units 41b return from the single-domain state to the multi-domain state. When the current I≥Imin, the liquid crystal dielectric elastomer 41 returns to the curved state; when the current I<Imin, the liquid crystal dielectric elastomer 41 remains in the straightened state.

[0085] It should be noted that the structure of the liquid crystal dielectric elastomer 41 can be a thin film or a fiber layer, which is not limited here.

[0086] The number of the pressure sensors 43 and the number of the wire storage holes 23 are both multiple, and the pressure sensors 43 are arranged one-to-one with the wire storage holes 23. Thus, the blood flow pressure information outside the main pipe 20 can be accurately received by using these pressure sensors 43.

[0087] It should be noted that the pressure sensor 43 is used to generate an electric current signal when the main body section 21 is pressed by the blood flow in the blood vessel. The current amplifier 42 amplifies the electric current signal from the pressure sensor 43. In some embodiments, the pressure sensor 43 is a resistance strain gauge, i.e. under the action of pressure, the resistance strain gauge embedded in the polymer outer layer 211 will be slightly deformed, resulting in a change in resistance value, thereby changing the current value, achieving the effect of deformation and bending of the liquid crystal dielectric elastomer 41. The material of the resistance strain gauge includes but is not limited to constantan or nichrome wire.

[0088] Again in combination Figure 4 As shown in some embodiments, the pressure control assembly 40 includes a circuit board 44, a power supply 45, a switch 46 and a wire 47. The circuit board 44 and the power supply 45 are arranged in the handle shell 11 of the control handle 10, the switch 46 is installed on the handle shell 11, and the operating part of the switch 46 is exposed outside the handle shell 11, so as to facilitate the relevant control operation through the switch 46.

[0089] The material of the circuit board 44 is PCB, which is the carrier of the circuit and other components. The power supply 45 can be an alkaline dry battery, a lithium battery or a polymer battery, etc., and preferably a lithium battery is used as the power supply 45. The switch 46 includes but is not limited to a button switch with light, a self-locking switch or a common push button switch. The wire 47 can be a multi-strand copper wire, and the outside of the multi-strand copper wire can be covered with an insulating outer layer.

[0090] The wire 47 connects the liquid crystal dielectric elastomer 41, the current amplifier 42, the pressure sensor 43 and the circuit board 44, so as to continuously supply power or transmit electric signals to these electronic components.

[0091] In combination Figure 4 And Figure 11 As shown in some embodiments, the pressure control assembly 40 further includes an LED screen 48. In this embodiment, the LED screen 48 is electrically connected with the current amplifier 42. The LED screen 48 is used to receive and display the electric current signal of the pressure sensor 43 processed by the current amplifier 42.

[0092] In order to facilitate understanding, the use process of the guide wire connection guide tube 100 of one of the embodiments will be described below, but it is not intended to limit the use process of the guide wire connection guide tube 100 of the present application to this.

[0093] When using the guide wire connection guide tube 100, physiological saline can be injected into the main tube 20 through the luer connector 102 to flush and heparinize the inner cavity of the main tube 20. When the catheter 1 reaches the lesion site along the path and cannot pass through, the reverse penetration method can be adopted to increase an additional puncture point to penetrate the guide wire 2, and the guide wire 2 is merged with the catheter 1 after passing through the lesion to assist in establishing the path.

[0094] For example, in the embodiment of the present application, the switch 46 on the control handle 10 is turned on, at which time the pressure control assembly 40 starts to work. In the embodiment where the pressure control assembly 40 comprises the LED screen 48, the pressure in each direction of the main tube 20 is displayed by the LED screen 48. The pressure is smaller where the blood flow speed is faster, and the pressure is larger where the blood flow speed is slower. When the pressure in a certain direction increases, i.e. the main tube 20 is deflected, the pressure control assembly 40 controls the main tube 20 to bend, so that the catheter 1 is always in the central position. By operating the active knob 341 on the control handle 10, the flared section 22 starts to flare. The rotation angle of the active knob 341 can be adjusted to adjust the flaring angle of the flared section 22, so that the flared section 22 reaches a suitable flaring angle. After the flaring angle of the flared section 22 is adjusted, the reverse-traveling guide wire 2 is more easily passed through the flared section 22 of the main tube 20 into the main tube 20, thereby shortening the reverse-traveling time and improving the success rate of reverse traveling.

[0095] The specifications or quantities of the elements in the guide wire connection guide tube 100, or the materials, are not limited herein, as long as the guide wire connection guide tube 100 can adapt to the corresponding functions and effects.

[0096] For the convenience of understanding, the structure of the guide wire connection guide tube 100 will be further described below.

[0097] In some embodiments, the guide wire connection guide tube 100 has a specification of 8F and an effective length of 1350 mm, and is suitable for femoral-popliteal-iliac position connection and reverse traveling of the guide wire 2.

[0098] In some embodiments, the main tube 20 has an outer diameter of 2.67 mm, an inner diameter of 0.95 mm, and a length of 1500 mm. Among them, the main body section 21 has a length of 1400 mm, and the flared section 22 has a length of 100 mm.

[0099] The number of the wire storage holes 23 in the main body section 21 can be 4. The wire storage holes 23 are uniformly distributed in the circumferential direction. The diameter of the wire storage hole 23 can be 0.45 mm. The wire storage hole 23 can be a through hole extending through the entire main tube 20, or can be a hole extending from the proximal end of the main tube 20 to the flared section 22. As long as the wire storage hole 23 can be used to pull the flared section 22 by using the wire elements such as the passive wire 31, the active wire 32 or the traction wire 33, the flared section 22 can be flared.

[0100] The wire 47, the liquid crystal dielectric elastomer 41, the current amplifier 42 and the pressure sensor 43 of the pressure control assembly 40 can be embedded in the polymer outer layer 211, or can be arranged on the inner wall of the main body section 21 surrounded by the polymer outer layer 211.

[0101] The number of wires 47, liquid crystal dielectric elastomer 41, current amplifier 42 and pressure sensor 43 of the pressure control assembly 40 is consistent with the number of the wire storage holes 23 distributed circumferentially.

[0102] In some embodiments, the overall single-side thickness of the main body section 21 is not more than 300 um. The material of the polymer outer layer 211 can be Pebax5533, which has both rigidity and flexibility, and the single-side wall thickness is 100 um.

[0103] In some embodiments, the passive wire 31 has an outer diameter of 0.15 mm and a length of 1390 mm, which is pushed into the bottom of the wire storage hole 23 in a hot melt welding manner. The active wire 32 has an outer diameter of 0.25 mm and a length of 1420 mm, which is pulled out from the catheter 1 at 1390 mm, with 30 mm of the tail end exposed, and the distal end is firmly welded with the passive wire 31.

[0104] The number of active wires 32 and passive wires 31 is consistent with the number of wire storage holes 23. For example, the tail end of the four active wires 32 is welded with the traction wire 33, which has an outer diameter of 0.40 mm and a length of 30 mm. The tail end of the traction wire 33 is connected with the control handle 10, and the traction wire 33 can be pulled back to realize the flaring of the flaring section 22.

[0105] In some embodiments, the materials of the passive wire 31, the active wire 32 and the traction wire 33 are all 304 stainless steel. The elastic outer layer 221 is TPU, the developing material is W, and the doping ratio is 40%. The flaring section 22 is connected with the main body section 21 by melting welding.

[0106] The stress dispersion tube 101 is made of silica gel, has a length of 20 mm, an outer diameter of 22.0 mm, and an inner hole diameter of 2.80 mm, and is inserted into the distal end of the main pipe 20 to prevent the catheter 1 from being bent under stress.

[0107] The luer connector 102 is made of PC material, has an inner hole of 2.87 mm, and a hole depth of 10.0 mm. The luer connector 102 is connected with the main pipe 20 by adhesive.

[0108] The control handle 10 has a length of 130 mm and a width of 50 mm. In the embodiment in which the handle shell 11 includes the first shell 111 and the second shell 112, the wall thickness of the first shell 111 and the second shell 112 can be 2.5 mm, and the length can be 90 mm.

[0109] In the embodiment in which the rotating mechanism 34 includes the active knob 341, the fixed knob 342, the passive knob 343 and the movable screw 344. The active knob 341 has an outer diameter of 60 mm and a length of 20 mm, and the outer layer is uniformly distributed with patterns to prevent slipping during rotation.

[0110] In some embodiments, the liquid crystal dielectric elastomer 41 is a thermally responsive material, such as a carbon nanotube-doped gel or a metal-doped acrylic resin. In this embodiment, the liquid crystal dielectric elastomer 41 is in fibrous form, with a single-sided wall thickness of 250 μm. The liquid crystal dielectric elastomer 41 is initially in a bent state with a bending angle of 20° to 30°. At room temperature, the liquid crystal dielectric elastomer 41 is stretched and shaped. The liquid crystal cells 41b are oriented axially.

[0111] Combination Figure 9 As shown, when switch 46 is pressed, the circuit is energized, and the liquid crystal dielectric elastomer 41 begins to heat up. When the current is greater than the threshold, it returns to its bent shape. When the current is less than the threshold, it returns to its horizontal state.

[0112] In some embodiments, the pressure sensor 43 is a resistance strain gauge, which can be made of nichrome wire and has a wire strain gauge structure. When the blood vessel pressure increases, the resistance decreases and the current increases. The current amplifier 42 is connected to the liquid crystal dielectric elastomer 41 and the pressure sensor 43. The current generated during the amplification process causes the current to reach the deformation threshold of the liquid crystal dielectric elastomer 41, and at the same time, the amplified signal is transmitted to the LED screen 48 to achieve the normal operating current of the LED screen 48.

[0113] Example 2

[0114] The guide wire to guide tube 100 in Embodiment 2 has the same basic structure as the guide wire to guide tube 100 in Embodiment 1. The difference is that... Figure 13 As shown, in Embodiment 2, the main body section 21 of the main pipe 20 is also provided with an annular light strip 49 on its pipe wall.

[0115] The length of the annular light strip 49 is consistent with that of the liquid crystal dielectric elastomer 41. The liquid crystal dielectric elastomer 41 is connected to the outside of the annular light strip 49, and the specific connection method includes, but is not limited to, adhesive bonding.

[0116] In some embodiments, the ring-shaped light strip 49 has a wall thickness of 50 μm, and the liquid crystal dielectric elastomer 41 has a wall thickness of less than or equal to 250 μm.

[0117] In Example 2, combined with Figure 14 As shown, the annular light strip 49 is connected in series with the current amplifier 42 and the pressure sensor 43, so that the current amplified by the current amplifier 42 flows through the annular light strip 49. The annular light strip 49 can emit light of different wavelengths to irradiate the liquid crystal dielectric elastomer 41 and produce different deformations. For example, the annular light strip 49 can emit 365nm ultraviolet light and 460nm visible light. The liquid crystal dielectric elastomer 41 can be photoresponsive. In this embodiment, the liquid crystal dielectric elastomer 41 is not directly connected to the circuit, but is connected to the outside of the annular light strip 49, and the light emitted by the annular light strip 49 is used to excite the liquid crystal dielectric elastomer 41 to deform.

[0118] In combination Figure 15 As shown in FIG. 4, under the irradiation of 365 nm ultraviolet light, the liquid crystal dielectric elastomer 41 restores to the curved state; under the irradiation of 460 nm visible light or heating, the liquid crystal dielectric elastomer 41 remains in the straightened state.

[0119] In some embodiments, the material of the liquid crystal dielectric elastomer 41 is an acryl resin material with azobenzene groups. In this way, under the irradiation of 365 nm ultraviolet light, the azobenzene groups are converted from the stable trans structure to the cis structure, driving the material as a whole to bend towards the light source; under the irradiation of 460 nm visible light or heating, the material reverts to the straightened state.

[0120] It should be noted that in this embodiment 2, the pressure control assembly 40 can also include a circuit board 44, a power supply 45, a switch 46 and a wire 47. The switch 46 is connected in series with the ring-shaped light belt 49. The switch 46 is arranged on the control handle 10 and is used to select the ultraviolet light or visible light emitted by the ring-shaped light belt 49.

[0121] The switch 46 can be a multi-mode light button switch 46, and the colors of the ring-shaped light belt 49 correspond to the modes of the light button switch 46 one by one. Taking the case that the ring-shaped light belt 49 can emit 365 nm ultraviolet light and 460 nm visible light as an example. For example, the switch 46 is pressed once, the purple light source on the switch 46 is turned on, the ring-shaped light belt 49 emits ultraviolet light, and the wavelength can be 365 nm. The switch 46 is continuously pressed twice, the purple light source on the switch 46 is turned off, the green light source is turned on, the ultraviolet light of the ring-shaped light belt 49 is turned off, and the visible light is turned on, and the wavelength can be 460 nm. The switch 46 is continuously pressed three times, and the light is turned off. It should be noted that the continuous pressing of the switch 46 is similar to the double-click operation of the switch 46, that is, the continuous here refers to the repeated pressing of the switch 46 within a very short preset time period. The preset time period can be 0.5 s to 2 s, which is not limited here.

[0122] In combination Figure 14 As shown in FIG. 4, under the irradiation of 365 nm ultraviolet light, the liquid crystal dielectric elastomer 41 restores to the curved state; under the irradiation of 460 nm visible light or heating, the liquid crystal dielectric elastomer 41 remains in the straightened state.

[0123] Embodiment 3

[0124] The guide wire connection guide tube 100 of embodiment 2 is consistent with the basic structure of the guide wire connection guide tube 100 of embodiment 2. Based on the series connection of the current amplifier 42, the pressure sensor 43 and the ring-shaped light strip 49 to the switch 46, the current amplifier 42 amplifies the current generated by the pressure sensor 43 due to the deformation to generate a current in the entire loop. The difference is that in embodiment 3, the light-emitting color of the ring-shaped light strip 49 can be adjusted according to the current size, so that the switch 46 does not need to be a multi-mode lighted button switch 46 to indicate the state of the liquid crystal dielectric elastomer 41 triggered by the ring-shaped light strip 49. When the current amplified by the current amplifier 42 is greater than or equal to a preset value, the liquid crystal dielectric elastomer 41 returns to the curved state; when the current amplified by the current amplifier 42 is less than the preset value, the liquid crystal dielectric elastomer 41 remains in the straightened state.

[0125] For example, when the current is less than the threshold value Imin, the ring-shaped light strip 49 is a visible light color, and the wavelength can be 460 nm, at which time the liquid crystal dielectric elastomer 41 is in a straightened state. When the current is greater than or equal to the threshold value Imin, the ring-shaped light strip 49 changes from visible light to ultraviolet light. The wavelength of the ultraviolet light can be 360 nm, at which time the liquid crystal dielectric elastomer 41 starts to bend, driving the main tube 20 to return to the correct position. In this way, automatic bending control is achieved in embodiment 3. Therefore, the switch 46 can be a single-mode lighted button switch 46, or a multi-mode lighted button switch 46 as in embodiment 2, and the selection of the switch 46 in embodiment 3 is not limited.

[0126] In summary, the guide wire connection guide tube 100 adopting the embodiments of the present application has at least one of the following technical effects:

[0127] 1. Compared with the related art, when a doctor uses a corresponding sheath or guide tube as a guide tube for reverse threading of a guide wire, the inner diameter of the sheath and the guide tube is small, and it takes a long time for the guide wire to pass through the guide tube, and it is easy to cause deviation of the guide wire and the guide tube, resulting in failure to complete the connection. The guide wire connection guide tube 100 of the present application can be manually flared to increase the inner diameter of the flared section 22 of the distal end of the guide wire connection guide tube 100, thereby facilitating the connection of the reverse threaded guide wire 2, reducing the reverse threading time, and improving the reverse threading success rate.

[0128] 2. In the related art, the guide tube is usually not in a centered state during the intervention process, and the position of the guide tube needs to be manually adjusted according to the DSA image during connection. The guide wire connection guide tube 100 provided by the present application can adjust the position in real time according to the pressure changes in each direction in the blood vessel, so that the flared section 22 tends to be in a centered state, making it more convenient for the guide wire 2 to pass in.

[0129] 3. The control handle 10 is ergonomically designed and can be operated by one hand.

[0130] In this application, unless specifically defined otherwise, the terms "mounting", "connected", "connecting", "fixed", and "fixedly" mean to be connected, fixed, or both, either directly or indirectly through intermediaries, and can include wired or wireless connections. The term "and / or" includes combinations thereof.

[0131] It should be noted that in the embodiments of the present application, the terms "first", "second" are used only for descriptive purposes, and cannot be construed as indicating or implying relative importance or implicitly indicating the number of the technical features indicated. Therefore, the features defined with "first", "second" can explicitly or implicitly include at least one of the features. In the description of the present application, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise specifically defined.

[0132] In this application, unless otherwise specifically defined and limited, the first feature is "on" or "under" the second feature, which can be direct contact between the first and second features, or indirect contact between the first and second features through an intermediate medium.

[0133] The technical features of the above embodiments can be combined in any way. To make the description simple, all possible combinations of the technical features in the above embodiments are not described, but as long as the combination of the technical features does not exist, it should be considered as the scope of the present application.

[0134] The above embodiments only express several embodiments of the present application, and the description is more specific and detailed, but it should not be understood as limiting the scope of the patent of the present application. It should be noted that for ordinary skilled in the art, without departing from the inventive concept of the present application, a number of modifications and improvements can be made, which are all within the scope of the present application. Therefore, the scope of protection of the patent of the present application should be subject to the appended claims.

Claims

1. A guide wire guide tube, characterized in that, include: Control handle; The main tube includes a main body section and a flared section. The proximal end of the main body section is connected to the control handle, and the distal end of the main body section is connected to the proximal end of the flared section. The tube wall of the main tube is provided with a wire storage hole, and the flared section includes an elastic outer layer, with the wire storage hole extending to the elastic outer layer. The flaring control assembly includes a passive wire, a active wire, a traction wire, and a rotating mechanism. The distal end of the passive wire passes through the wire storage hole to the elastic outer layer. The passive wire and the wire storage hole are fixed to the inner wall of the elastic outer layer. The distal end of the active wire is connected to the distal end of the passive wire. The rotating mechanism is located on a control handle and is used to pull the active wire through the traction wire. The guide wire connection tube also includes a pressure control assembly. The pressure control assembly includes a liquid crystal dielectric elastomer, a current amplifier, and a pressure sensor. The liquid crystal dielectric elastomer, the current amplifier, and the pressure sensor are all embedded in the tube wall of the main body section. The pressure sensor generates a current signal when the main body section is squeezed by blood flow in the blood vessel. The current amplifier amplifies the current signal from the pressure sensor, causing the liquid crystal dielectric elastomer to deform and bend under the action of current, thereby adjusting the degree of bending of the main body section.

2. The guide wire connection guide tube according to claim 1, characterized in that, The main tube has multiple wire storage holes inside its wall. Each wire storage hole is provided with a driving wire and a passive wire. Multiple driving wires are wound into one and connected to one end of the traction wire. The other end of the traction wire is connected to the rotating mechanism.

3. The guide wire guide tube according to claim 1 or 2, characterized in that, The flaring angle of the flared section is 0° to 90°, and / or the elastic outer layer comprises a thermoplastic elastomer material.

4. The guide wire connection guide tube according to claim 3, characterized in that, The rotating mechanism includes an active knob, a fixed knob, a passive knob, and a movable screw. The active knob is coaxially connected to the fixed knob and can rotate relative to the fixed knob. The active knob is fixed to the passive knob. One side of the active knob and the fixed knob has a through hole for placing the movable screw and allowing the movable screw to move axially. The movable screw is threadedly engaged with the passive knob, and the distal end of the movable screw is connected to the traction wire.

5. The guide wire connection guide tube according to claim 1, characterized in that, There are multiple pressure sensors and multiple wire storage holes, and each pressure sensor is set in a one-to-one correspondence with a wire storage hole.

6. The guide wire connection guide tube according to claim 1, characterized in that, The pressure sensor includes a resistance strain gauge.

7. The guide wire connection guide tube according to claim 6, characterized in that, The strain gauge is made of constantan or nichrome wire.

8. The guide wire guide tube according to claim 1, characterized in that, The liquid crystal dielectric elastomer, the current amplifier, and the pressure sensor are connected in series. When the current amplified by the current amplifier is greater than or equal to a preset value, the liquid crystal dielectric elastomer deforms back to a bent state; when the current amplified by the current amplifier is less than the preset value, the liquid crystal dielectric elastomer remains in a straight state.

9. The guide wire connection guide tube according to claim 1, characterized in that, The liquid crystal dielectric elastomer is photoresponsive. The tube wall of the main body section is also provided with an annular light strip. The liquid crystal dielectric elastomer is connected to the outside of the annular light strip. The annular light strip is connected in series with the current amplifier and the pressure sensor, so that the current amplified by the current amplifier flows through the annular light strip. The annular light strip can emit ultraviolet light and visible light. Under ultraviolet light irradiation, the liquid crystal dielectric elastomer deforms and returns to a bent state; under visible light irradiation or heating, the liquid crystal dielectric elastomer remains in a straight state.

10. The guide wire guide tube according to claim 9, characterized in that, The ring-shaped light strip is connected in series with a switch, which is located on the control handle. The switch is used to select whether the ring-shaped light strip emits ultraviolet light or visible light. Alternatively, the color of the ring-shaped light strip can be adjusted according to the current. When the current is less than a threshold, the ring-shaped light strip emits visible light; when the current is greater than or equal to the threshold, the ring-shaped light strip changes from visible light to ultraviolet light.

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