Method and device for monitoring changes in human microcirculation

Abstract

The present invention relates to the field of medical detection technology, and in particular discloses a method and device for monitoring changes in human microcirculation, including selecting a first judgment mode as a microcirculation judgment mode in response to a start instruction; in the first judgment mode, determining the microcirculation state of the patient according to the surface skin temperature and the cavity temperature; in response to the judgment result that the ambient temperature meets the first switching condition, switching the microcirculation judgment mode to a second judgment mode; in the second judgment mode, determining the microcirculation state of the patient according to the surface skin temperature and the ideal surface skin temperature corresponding to the ambient temperature; in response to the judgment result that the ambient temperature meets the second switching condition, switching to the first judgment mode. Based on the information such as the surface skin temperature and the cavity temperature at a specific limb of the patient to evaluate the changes in the patient's microcirculation, non-invasive monitoring of the changes in the patient's microcirculation can be achieved, and then early warning analysis of the patient's condition can be achieved according to the changes in the patient's microcirculation.

Description

Technical Field

[0001] The present invention relates to the field of medical detection technology, and in particular to a method and device for monitoring changes in human microcirculation. Background Art

[0002] Shock refers to an acute systemic critical pathological process in which the effective circulating blood volume decreases sharply and the tissue blood perfusion volume is seriously insufficient under the influence of strong pathogenic factors such as severe blood loss, fluid loss, infection, and trauma, causing cell ischemia and hypoxia, resulting in functional and metabolic disorders and structural damage to important organs. A large number of studies have confirmed that shock is closely related to changes in microcirculation. Shock has different clinical manifestations at different stages, including microcirculatory spasm, microcirculatory stasis, and microcirculatory failure. A few hours before the patient's macrocirculatory physiological indicators (such as cardiac output, oxygen delivery, systemic blood flow, perfusion pressure, etc.) change, there is usually a decrease in microcirculatory blood flow, resulting in insufficient blood flow to the limbs, cold hands and feet, etc. When the patient's macrocirculatory physiological indicators drop sharply, the microcirculatory disorder usually enters the microcirculatory failure stage, and serious complications such as systemic organ failure occur frequently, which are difficult to treat and threaten life at any time.

[0003] The applicant noted that the "Apparatus and method for assessing the condition of critically ill patients" (US Patent No. US4306569A) invented by MAX H. WEIL et al. discloses a method and device for assessing the condition of patients with circulatory shock by measuring the patient's peripheral or skin temperature. In the technical solution of this patent, the difference between the patient's toe temperature and the ambient temperature is measured. Specifically, the gradient of the difference between the toe temperature and the ambient temperature is calculated. If the difference between the toe temperature and the ambient temperature does not rise by at least a predetermined value (such as 3°C) within a predetermined time (such as ten hours), an indication of the patient's poor condition is given. The applicant noted that in this patent, the condition is assessed only by the difference between the patient's toe and ambient temperature and its rate of change (gradient). Such an indicator is single. If the ambient temperature of the patient changes rapidly (such as changes in the temperature control of the air conditioning system, changes in the weather, and the patient is transferred to another place), the system will misjudge the patient's condition. Therefore, it is necessary to provide a method and device for monitoring changes in human microcirculation that can identify microcirculatory disorders as early as possible, and such a device can eliminate the interference of rapid changes in ambient temperature on the monitoring results as much as possible. Summary of the invention

[0004] Based on this, it is necessary to provide a monitoring method and device for human microcirculation changes that can identify microcirculation disorders as early as possible, and such a device can eliminate the interference of rapid changes in ambient temperature on the monitoring results as much as possible.

[0005] A method for monitoring changes in human microcirculation, comprising: selecting a first judgment mode as a microcirculation judgment mode in response to a start instruction; in the first judgment mode, monitoring the ambient temperature, the surface skin temperature of a patient's specific limb, and the intracavitary temperature of the patient; determining the microcirculation state of the patient according to the surface skin temperature and the intracavitary temperature; in response to a judgment result that the ambient temperature meets a first switching condition, switching the microcirculation judgment mode to a second judgment mode; in the second judgment mode, monitoring the ambient temperature and the surface skin temperature of the patient's specific limb; determining the microcirculation state of the patient according to the surface skin temperature and an ideal surface skin temperature corresponding to the ambient temperature; and switching to the first judgment mode in response to a judgment result that the ambient temperature meets a second switching condition.

[0006] The above-mentioned method for monitoring changes in human microcirculation enters the first judgment mode after receiving the start instruction. In the first judgment mode, the ambient temperature, the surface skin temperature of the patient's specific limbs and the patient's intracavitary temperature are monitored in real time, and the patient's microcirculation state is determined according to the surface skin temperature and the intracavitary temperature. When the ambient temperature meets the first switching condition, it switches to the second judgment mode. In the second judgment mode, the ambient temperature and the surface skin temperature of the patient's specific limbs are monitored in real time, and the patient's microcirculation state is determined according to the ideal surface skin temperature corresponding to the surface skin temperature and the ambient temperature. When the ambient temperature meets the second switching condition, it switches to the first judgment mode. Based on the information such as the surface skin temperature of the patient's specific limbs and the patient's intracavitary temperature, the changes in the patient's microcirculation are evaluated, and non-invasive monitoring of the patient's microcirculation changes can be achieved, and then the early warning analysis of the patient's condition can be achieved according to the changes in the patient's microcirculation. Selecting the first judgment mode or the second judgment mode as the microcirculation judgment mode based on the ambient temperature can reduce the influence of the ambient temperature on the evaluation results of the patient's microcirculation state, and improve the accuracy of the evaluation results of the patient's microcirculation state.

[0007] In one of the embodiments, the first switching condition is that a first change value of the ambient temperature within a first preset time period is greater than or equal to a first threshold.

[0008] In one of the embodiments, the second switching condition is that a second change value of the ambient temperature within a second preset time period is less than a second threshold value.

[0009] In one embodiment, determining the microcirculation status of the patient based on the body surface skin temperature and the intracavitary temperature includes judging that insufficient microcirculation occurs in a specific limb of the patient when the body surface skin temperature is lower than the intracavitary temperature and a first difference between the intracavitary temperature and the body surface skin temperature is greater than a third threshold.

[0010] In one embodiment, after determining that the patient has microcirculation insufficiency, the method further includes monitoring changes in the first difference within a third preset time period; when the first difference gradually decreases within the third preset time period, it is determined that the patient's microcirculation blood flow has entered a recovery state; when the first difference gradually increases within the third preset time period, it is determined that the patient's microcirculation blood flow has entered a deterioration state.

[0011] In one embodiment, determining the microcirculation state of the patient based on the body surface skin temperature and the ideal body surface skin temperature corresponding to the ambient temperature includes determining the ideal body surface skin temperature corresponding to the current ambient temperature based on the correspondence between the ambient temperature and the ideal body surface skin temperature at a specific limb; when the body surface skin temperature is lower than the ideal body surface skin temperature and a second difference between the ideal body surface skin temperature and the body surface skin temperature is greater than a fourth threshold, it is determined that the patient has insufficient microcirculation.

[0012] In one embodiment, after determining that the patient has microcirculation insufficiency, the method further includes monitoring changes in the second difference within a fourth preset time period; when the second difference gradually decreases within the fourth preset time period, it is determined that the patient's microcirculation blood flow has entered a recovery state; when the second difference gradually increases within the fourth preset time period, it is determined that the patient's microcirculation blood flow has entered a deterioration state.

[0013] A monitoring device for changes in human microcirculation, comprising a body surface temperature monitoring module for monitoring the body surface skin temperature of a specific limb of a patient; an intracavity temperature monitoring module for monitoring the intracavity temperature of the patient; an ambient temperature monitoring module for monitoring the ambient temperature; a control module, respectively connected to the body surface temperature monitoring module, the intracavity temperature monitoring module and the ambient temperature monitoring module, for responding to a start instruction and selecting a first judgment mode as a microcirculation judgment mode; in the first judgment mode, monitoring the ambient temperature, the body surface skin temperature of the specific limb of the patient and the intracavity temperature of the patient; determining the microcirculation state of the patient according to the body surface skin temperature and the intracavity temperature; switching the microcirculation judgment mode to a second judgment mode in response to a judgment result that the ambient temperature meets a first switching condition; in the second judgment mode, monitoring the ambient temperature and the body surface skin temperature of the specific limb of the patient; determining the microcirculation state of the patient according to the body surface skin temperature and the ideal body surface skin temperature corresponding to the ambient temperature; and switching to the first judgment mode in response to a judgment result that the ambient temperature meets a second switching condition.

[0014] In one embodiment, the body surface temperature monitoring module includes one or more skin temperature sensors, and the skin temperature sensor is fixed to the specific limb of the patient through a thermal insulation protective material.

[0015] In one embodiment, when the patient's specific limbs are the toes of both feet of the patient, the body surface temperature monitoring module determines the maximum value of the collected toe temperature as the body surface skin temperature.

[0016] In one embodiment, the device for monitoring changes in human microcirculation also includes a display module, which is connected to the control module and is used to display the ambient temperature, the skin temperature of a specific limb of the patient and the intracavitary temperature of the patient; the control module is also used to output different control signals according to different microcirculation states of the patient, and the display module is also used to display warning information according to the control signal. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the implementation methods of this specification or the technical solutions in the prior art, the drawings required for use in the implementation methods or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some implementation methods recorded in this specification. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0018] Figure 1 This is a schematic diagram of a flow chart of a method for monitoring changes in human microcirculation in one embodiment of the present application;

[0019] Figure 2 A schematic diagram of a continuous trend change curve of ambient temperature in one of the embodiments of the present application;

[0020] Figure 3 This is a flow chart of a method for determining the microcirculation status of a patient in a first judgment mode in one embodiment of the present application;

[0021] Figure 4 A schematic diagram of a continuous trend change curve of the temperature in the cavity and the temperature of the toes in one embodiment of the present application;

[0022] Figure 5 This is a flow chart of a method for determining the microcirculation status of a patient in the second judgment mode in one embodiment of the present application;

[0023] Figure 6 A schematic diagram of a comparison table of ambient temperature-ideal skin temperature in one of the embodiments of the present application;

[0024] Figure 7 A schematic diagram of a continuous trend change curve of the temperature in the cavity and the temperature of the toes in one embodiment of the present application;

[0025] Figure 8 This is a schematic diagram of the structure of a device for monitoring changes in human microcirculation in one of the embodiments of the present application. DETAILED DESCRIPTION

[0026] In order to facilitate the understanding of the present invention, the present invention will be described more fully below with reference to the relevant drawings. The preferred embodiments of the present invention are given in the drawings. However, the present invention can be implemented in many different forms and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to understand the disclosure of the present invention more thoroughly and comprehensively.

[0027] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art of the present invention. The terms used herein in the specification of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention. The term "and / or" used herein includes any and all combinations of one or more related listed items.

[0028] The present application provides a method for monitoring changes in human microcirculation, which can non-invasively monitor changes in a patient's microcirculation, and can then provide an early warning of worsening shock conditions based on changes in the patient's microcirculation, making it easier for medical staff to intervene in the patient early.

[0029] In some embodiments, the method for monitoring changes in human microcirculation can be executed by a control module in a device for monitoring changes in human microcirculation. For example, the method for monitoring changes in human microcirculation can be stored in the control module in the form of a program or instruction, and when the program or instruction is executed, the method for monitoring changes in human microcirculation can be implemented. The device for implementing the method for monitoring changes in human microcirculation disclosed in the present application can be a device with a large amount of computing resources (for example, a computer, a server, cloud computing, etc.), or a device with limited computing resources (for example, a hardware circuit such as an FPGA chip board and an ASIC chip board).

[0030] Figure 1 This is a flow chart of a method for monitoring changes in human microcirculation in one of the embodiments of the present application. In one of the embodiments, the method for monitoring changes in human microcirculation may include the following steps S100 to S700.

[0031] Step S100: In response to the start instruction, the first judgment mode is selected as the microcirculation judgment mode.

[0032] Since the patient's skin temperature is often greatly affected by the ambient temperature, when judging the patient's microcirculation state based on the patient's body temperature, different microcirculation judgment modes are designed and different judgment modes are used to determine the patient's microcirculation state under different environmental conditions to reduce the impact of the ambient temperature on the judgment accuracy. In the embodiment of the present application, the microcirculation judgment mode may include a first judgment mode and a second judgment mode, that is, the first judgment mode or the second judgment mode is used to judge the patient's microcirculation state based on the ambient temperature.

[0033] Under normal circumstances, the ambient temperature of the patient is stable (for example, in hospital monitoring or emergency monitoring). Therefore, in this embodiment, the first judgment mode can be used as the default mode, that is, after receiving the start-up instruction and starting the microcirculation monitoring of the patient, the first judgment mode is selected by default to judge the patient's microcirculation status.

[0034] Step S200: In the first judgment mode, the ambient temperature, the skin temperature at a specific limb of the patient, and the intracavitary temperature of the patient are monitored.

[0035] Ambient temperature is a physical quantity used to indicate the degree of hotness or coldness of the patient's environment. The monitoring device for changes in human microcirculation may be provided with an ambient temperature monitoring module, which is used to monitor the ambient temperature in real time.

[0036] Considering that when the microcirculatory blood flow of patients decreases, they are prone to hypothermia of the hands and feet due to insufficient blood flow to the limbs. Therefore, in the embodiments of the present application, the patient's specific limbs may refer to the patient's limbs, such as fingers, toes, and brain. Since the toes are the farthest extremities of the human body from the heart, it is more accurate to monitor the patient's microcirculation status based on the skin temperature at the toe position. In a preferred embodiment, the patient's specific limbs refer to the toes. The monitoring device for changes in human microcirculation can also be provided with a surface temperature monitoring module, which uses the surface temperature monitoring module to monitor the surface skin temperature of the patient's specific limbs in real time.

[0037] The temperature inside the human body can be called the intracavitary temperature, which is also an important medical vital sign and often changes with the patient's physical condition. The monitoring device for changes in human microcirculation can also be provided with an intracavitary temperature monitoring module, which is used to non-invasively monitor the patient's intracavitary temperature by measuring the temperature of the eardrum, oral cavity, esophagus, rectum, bladder, etc. In a preferred embodiment, the intracavitary temperature of the patient is measured through the rectum.

[0038] Step S300: determining the patient's microcirculation state according to the skin temperature and the intracavitary temperature.

[0039] When the first judgment mode is adopted according to the ambient temperature, the patient's microcirculation state can be determined according to the patient's skin temperature and the cavity temperature. In a feasible implementation, when the temperature in the patient's environment is in a relatively constant state, the change in the patient's skin temperature is mainly affected by the change in the patient's condition. Therefore, the patient's current microcirculation state can be determined according to the patient's skin temperature and the cavity temperature.

[0040] Step S400: In response to the judgment result that the ambient temperature satisfies the first switching condition, the microcirculation judgment mode is switched to the second judgment mode.

[0041] Considering that in actual patient monitoring, there may be situations where the patient is transferred or the temperature of the patient's environment changes significantly. For example, the patient is transferred from the emergency scene to the hospital by ambulance, or from Hospital A to Hospital B. Usually, the temperature of the human body's extremities is greatly affected by environmental changes, while the temperature in the human body's cavity changes less with the environment. Therefore, if the trend of the difference between the skin temperature at a specific limb position of the patient (such as toes) and the temperature in the patient's cavity is still compared when the ambient temperature changes greatly, it may lead to inaccurate judgment of the patient's microcirculation changes and draw wrong conclusions. Therefore, in the case of large changes in ambient temperature, the second judgment mode is used to determine the patient's microcirculation state, that is, the patient's current microcirculation state is judged based on the skin temperature at a specific limb position of the patient and the ideal skin temperature of the human body at the current ambient temperature.

[0042] While using the first judgment mode to monitor the patient's microcirculation status, the ambient temperature can also be monitored in real time, and whether the current ambient temperature has undergone a large temperature change can be determined by judging whether the ambient temperature meets the first switching condition. When the ambient temperature meets the first switching condition, it can be determined that the current ambient temperature has undergone a large temperature change. In this case, the microcirculation judgment mode can be switched to the second judgment mode, and the second judgment mode can be used to implement the patient's microcirculation status monitoring under the condition of large ambient temperature changes.

[0043] In practical applications, different first switching conditions can be designed according to different application scenarios, for example, the temperature change value of the ambient temperature within a fixed time exceeds a certain threshold, or the change rate of the ambient temperature exceeds a certain threshold.

[0044] Step S500: In the second determination mode, the ambient temperature and the skin temperature of a specific limb of the patient are monitored.

[0045] In the second judgment mode, the ambient temperature is monitored in real time by the ambient temperature monitoring module, and the body surface temperature monitoring module is used to monitor the body surface skin temperature of a specific limb of the patient in real time.

[0046] Step S600: determining the patient's microcirculation state according to the ideal body surface skin temperature corresponding to the body surface skin temperature and the ambient temperature.

[0047] When the second judgment mode is adopted according to the ambient temperature, the patient's microcirculation state can be determined according to the ideal skin temperature and the ambient temperature. In a feasible implementation, when the temperature in the patient's environment is in a state of large variation, the change in the patient's skin temperature is not only affected by the change in the patient's condition, but also by the ambient temperature. Therefore, when the ambient temperature varies greatly, the ideal skin temperature of the patient at the ambient temperature can be determined according to the ambient temperature, and then the patient's current microcirculation state can be determined according to the patient's actual skin temperature and the ideal skin temperature.

[0048] Step S700: In response to the judgment result that the ambient temperature satisfies the second switching condition, switching to the first judgment mode.

[0049] Considering that in actual patient monitoring, after the patient is transferred or other environmental temperature changes occur, the patient's environment may become stable, and it is more accurate to use the first judgment mode to determine the patient's microcirculation state when the environmental temperature is stable. Therefore, when switching to the second judgment mode, it is also possible to determine whether the environmental temperature has returned to a stable state by continuing to monitor the changes in the environmental temperature, so as to determine whether it is necessary to switch to the first judgment mode to determine the patient's current microcirculation state.

[0050] In this embodiment, it can be determined whether the current ambient temperature tends to be stable by determining whether the ambient temperature satisfies the second switching condition. When the ambient temperature satisfies the second switching condition, it can be determined that the current ambient temperature is in a stable state. In this case, the microcirculation determination mode can be switched to the first determination mode, and the first determination mode is used to implement patient microcirculation status monitoring in the case of large ambient temperature changes.

[0051] In practical applications, different second switching conditions can be designed according to different application scenarios, for example, the temperature change value of the ambient temperature within a fixed time is less than a certain threshold, or the change rate of the ambient temperature is less than a certain threshold.

[0052] The monitoring method of human microcirculation changes provided by the present application enters the first judgment mode after receiving the start instruction. In the first judgment mode, the ambient temperature, the surface skin temperature of the patient's specific limbs and the patient's intracavitary temperature are monitored in real time, and the patient's microcirculation state is determined according to the surface skin temperature and the intracavitary temperature. When the ambient temperature meets the first switching condition, it switches to the second judgment mode. In the second judgment mode, the ambient temperature and the surface skin temperature of the patient's specific limbs are monitored in real time, and the patient's microcirculation state is determined according to the ideal surface skin temperature corresponding to the surface skin temperature and the ambient temperature. When the ambient temperature meets the second switching condition, it switches to the first judgment mode. Based on the information such as the surface skin temperature of the patient's specific limbs and the patient's intracavitary temperature, the patient's microcirculation changes are evaluated, which can realize non-invasive monitoring of the patient's microcirculation changes, help to identify the patient's microcirculation abnormalities earlier, and realize early warning analysis of the patient's condition, which is very important for medical staff to intervene in the patient's condition deterioration in time. Selecting the first judgment mode or the second judgment mode as the microcirculation judgment mode based on the ambient temperature can reduce the influence of the ambient temperature on the evaluation results of the patient's microcirculation state and improve the accuracy of the evaluation results of the patient's microcirculation state.

[0053] In one embodiment, the first switching condition may be that a first change value of the ambient temperature within a first preset time period is greater than or equal to a first threshold. Specifically, when operating in the first judgment mode, the first change value of the ambient temperature within the first preset time period is continuously monitored.

[0054] The temperature of the patient's environment is continuously monitored by the ambient temperature monitoring module. The ambient temperature monitoring module can also generate a continuous trend change curve of the ambient temperature based on the monitoring data. Based on the continuous trend change curve of the ambient temperature, the change of the ambient temperature can be more intuitively understood. In this embodiment, the first change value can refer to the absolute value of the difference between the ambient temperatures at different times. For example, when the first preset time period is 1 hour, the absolute value of the difference between the current ambient temperature and the ambient temperature 1 hour ago can be calculated to determine the first change value.

[0055] When the first change value is greater than or equal to the first threshold, it can be determined that the first switching condition is met, and the microcirculation judgment mode is switched from the first judgment mode to the second judgment mode, that is, the second judgment mode is used to determine the patient's microcirculation state. When the first change value is greater than or equal to the first threshold, it indicates that the temperature change in the patient's environment is relatively large. In this case, the change in the patient's skin temperature is not only affected by the change in the patient's condition, but may also be affected by the change in the ambient temperature. Therefore, the second judgment mode can be used to determine the patient's microcirculation state.

[0056] The method for monitoring changes in human microcirculation provided in the present application is based on different changes in ambient temperature and selects different microcirculation judgment modes to determine the patient's microcirculation status, which can reduce the impact of ambient temperature on the judgment result and improve the judgment accuracy.

[0057] In one embodiment, when the first change value is less than the first threshold value, the first judgment mode is continued to be used to determine the patient's microcirculation state. When the first change value is less than the first threshold value, it indicates that the temperature change in the patient's environment is small. In this case, the change in the patient's skin temperature is mainly affected by the change in the patient's condition. Therefore, the first judgment mode can continue to be used to determine the patient's microcirculation state. In this embodiment, the first threshold value can be reasonably set according to actual application requirements. Preferably, the first threshold value can be a value greater than zero. For example, when the first preset time period is 1 hour and the first threshold value is set to 3°C, when it is detected that the first change value of the ambient temperature in 1 hour is less than 3°C (that is, the value of the increase or decrease in the ambient temperature in 1 hour is less than 3°C), it is judged that the first judgment mode is used to determine the patient's microcirculation state.

[0058] In one embodiment, the second switching condition may be that a second change value of the ambient temperature within a second preset time period is less than a second threshold value. Specifically, when operating in the second judgment mode, the second change value of the ambient temperature within the second preset time period is continuously monitored.

[0059] The temperature of the patient's environment is continuously monitored by the ambient temperature monitoring module. In this embodiment, the second change value may also refer to the absolute value of the difference between the ambient temperatures at different times. For example, when the second preset time period is 0.5 hours, the second change value may be determined by calculating the absolute value of the difference between the current ambient temperature and the ambient temperature 0.5 hours ago.

[0060] When the second change value is less than the second threshold, it can be determined that the second switching condition is met, and the microcirculation judgment mode is switched from the second judgment mode to the first judgment mode, that is, the first judgment mode is used to determine the patient's microcirculation state.

[0061] When the second change value is less than the fourth threshold, it indicates that the temperature change in the patient's environment is small, that is, the ambient temperature tends to be stable. In this case, it is more accurate to use the first judgment mode to determine the patient's microcirculation state. Therefore, when the second change value is less than the second threshold, the patient's microcirculation state can be determined based on the relationship between the skin temperature of a specific limb position (such as toes) of the patient and the temperature in the patient's cavity.

[0062] In this embodiment, the second threshold value can be reasonably set according to actual application requirements, and preferably, the second threshold value can be a value greater than zero. For example, when the second preset time period is 2 hours and the second threshold value is set to 0.2°C, after using the second judgment mode, when it is detected that the value of the ambient temperature increase or decrease in 2 hours is less than 0.2°C, it is judged that the ambient temperature tends to be stable, and it is judged to use the first judgment mode to determine the current microcirculation state of the patient.

[0063] In one embodiment, when the second change value is greater than or equal to the fourth threshold value, the second judgment mode can be continued to be used to determine the patient's microcirculation state. When the second change value is greater than or equal to the second threshold value, it indicates that the temperature change in the patient's environment is still relatively large. Therefore, in this case, it is more accurate to continue to use the second judgment mode to determine the patient's microcirculation state. That is, the patient's microcirculation state is determined based on the relationship between the actual body surface skin temperature at a specific limb position of the patient and the ideal body surface skin temperature at the current ambient temperature.

[0064] Figure 2 Schematic diagram of the continuous trend change curve of the ambient temperature in one of the embodiments of the present application. In this embodiment, Figure 2 The switching of the microcirculation judgment mode in the present application is explained by taking the ambient temperature change as an example. The description is relatively specific and detailed, but it cannot be understood as limiting the scope of the invention patent.

[0065] After receiving the start instruction and starting the microcirculation monitoring for the patient, the first judgment mode is selected by default to judge the microcirculation status of the patient. At the same time, the temperature change of the ambient temperature is monitored in real time, and the first change value of the ambient temperature at the first preset time is compared with the first threshold value to judge whether the judgment mode needs to be switched. Figure 2 In the embodiment, before time t2, the first change value of the ambient temperature in the first preset time period is less than the first threshold value, so the first judgment mode is maintained in the first time period T1 to judge the microcirculation state of the patient. Since the first change value between the ambient temperature at time t2 and the ambient temperature at time t1 is greater than or equal to the first threshold value, and the time difference between time t2 and time t1 is the first preset time period, the microcirculation judgment mode is switched at time t2, from the first judgment mode to the second judgment mode.

[0066] Similarly, the temperature change of the ambient temperature is monitored in real time, and whether the judgment mode needs to be switched is determined by comparing the second change value of the ambient temperature in the second preset time with the second threshold. Figure 2In the embodiment, between time t2 and time t4, the second change value of the ambient temperature in the second preset time period is greater than or equal to the second threshold value, so the second judgment mode is maintained to judge the microcirculation state of the patient in the second time period T2. Since the second change value between the ambient temperature at time t4 and the ambient temperature at time t3 is less than the second threshold value, and the time difference between time t4 and time t3 is the second preset time period, the microcirculation judgment mode is switched at time t4, from the second judgment mode to the first judgment mode. The first judgment mode is used to judge the microcirculation state of the patient in the third time period T3 starting from time t4.

[0067] Figure 3 This is a flow chart of a method for determining the microcirculation status of a patient in a first judgment mode in one of the embodiments of the present application. In one of the embodiments, in the first judgment mode, determining the microcirculation status of a patient based on the skin temperature and the intracavitary temperature may include the following step S310.

[0068] Step S310: When the skin temperature is lower than the cavity temperature, and a first difference between the cavity temperature and the skin temperature is greater than a third threshold, it is determined that insufficient microcirculation occurs in a specific limb of the patient.

[0069] The surface skin temperature of the patient's specific limb and the patient's intracavitary temperature are continuously measured, and the surface skin temperature and the intracavitary temperature are compared. When the surface skin temperature at a specific limb position of the patient (such as a toe) is lower than the intracavitary temperature, and the first difference between the intracavitary temperature and the surface skin temperature is greater than a third threshold, it indicates that a drop in body temperature has occurred at the specific limb position of the patient, so it can be determined that insufficient microcirculation has occurred at the specific limb position of the patient at this time. It should be noted that the first difference in the present application refers to the difference between the intracavitary temperature and the surface skin temperature. Since the surface skin temperature is lower than the intracavitary temperature at this time, the first difference is a positive number. The third threshold can be reasonably set according to actual application requirements. Preferably, the third threshold can be a value greater than zero.

[0070] In the method for monitoring changes in human microcirculation provided in the present application, in the first judgment mode, whether the patient has a problem of insufficient microcirculation is judged based on the relationship between the skin temperature at a specific limb position of the patient and the intracavitary temperature of the patient, thereby avoiding using the ambient temperature as a reference for judgment, and avoiding interference of external temperature fluctuations on the judgment results, thereby being able to more accurately reflect the state of the patient's microcirculation.

[0071] In one embodiment, after determining that microcirculation deficiency occurs in a specific limb of a patient, an early warning message of microcirculation deficiency may be generated. The early warning message is used to warn the patient of worsening shock, so that medical staff can intervene in the patient's condition early.

[0072] In one embodiment, see Figure 3 After determining that the patient has insufficient microcirculation, the method may further include the following steps S320 to S340.

[0073] Step S320: monitor the change of the first difference within a third preset time period.

[0074] When it is determined that the patient has insufficient microcirculation, the patient's microcirculation can be further analyzed based on the changes in the skin temperature and intracavitary temperature at specific limb locations of the patient to determine whether the patient's microcirculation is in a recovery state or a deterioration state. The feasibility of shock resuscitation of the patient can then be estimated based on the changes in the patient's microcirculation.

[0075] Step S330: When the first difference gradually decreases within the third preset time period, it is determined that the microcirculation blood flow of the patient has entered a recovery state.

[0076] Step S340: When the first difference gradually increases within the third preset time period, it is determined that the microcirculation blood flow of the patient has entered a deteriorating state.

[0077] Usually, microcirculation monitoring is performed on critically ill patients who are about to go into shock. At this time, the patient's intracavitary temperature is assumed to be normal. Generally, when the ambient temperature is stable, the patient's intracavitary temperature does not change much. When the patient's intracavitary temperature changes significantly, an alarm can be directly issued.

[0078] In the embodiment of the present application, the first judgment mode is used to determine the microcirculation state of the patient when the ambient temperature is relatively stable. The change trend of the first difference between the intracavitary temperature and the skin temperature of the patient's specific limb is continuously monitored, and a continuity trend change curve of the first difference can be generated based on the change of the first difference. The change of the first difference can be intuitively understood based on the continuity trend change curve of the first difference. Since the intracavitary temperature of the patient does not change much when the ambient temperature is stable, the change of the first difference is mainly affected by the temperature change of the patient's specific limb. When the first difference shows a gradually decreasing trend of change within the second preset time period, it indicates that the temperature of the patient's specific limb has risen, so it can be determined that the microcirculation blood flow at the patient's specific limb has entered a recovery state. When the first difference shows a gradually increasing trend of change within the second preset time period, it indicates that the temperature of the patient's specific limb has further decreased, so it can be determined that the microcirculation blood flow at the patient's specific limb has entered a deterioration state.

[0079] Figure 4 This is a schematic diagram of a continuous trend change curve of the cavity temperature and the toe temperature in one embodiment of the present application. In this embodiment, Figure 4Taking the changes in the temperature in the cavity and the toe temperature as an example, the first judgment mode used in the present application to judge the microcirculation state of a specific limb of a patient is described. The description is relatively specific and detailed, but it cannot be understood as limiting the scope of the invention patent.

[0080] When the first judgment mode is used to determine the patient's microcirculation state, at time t5, the patient's toe temperature is lower than the cavity temperature, and the first difference between the cavity temperature and the toe temperature is greater than the third threshold value, so it can be judged that the patient has insufficient microcirculation at the toe starting from time t5. In the case of judging that the patient has insufficient microcirculation, the change of the first difference between the cavity temperature and the toe temperature is continuously monitored. When it is monitored that the first difference gradually increases in the third preset time period between time t5 and time t6, it can be judged that the patient's microcirculation blood flow has entered a deteriorated state. From time t5 to time t7, the first difference continues to be in a gradually increasing state, so it can be judged that the patient's microcirculation blood flow is in a continuously deteriorating state. When it is monitored that the first difference gradually decreases in the third preset time period between time t8 and time t7, it can be judged that the patient's microcirculation blood flow has entered a recovery state from time t7.

[0081] In one embodiment, after determining that the microcirculatory blood flow in a specific limb of the patient has entered a recovery state, a prompt message of microcirculatory recovery can be generated to estimate the feasibility of shock resuscitation of the patient. After determining that the microcirculatory blood flow in a specific limb of the patient has entered a deterioration state, a warning message of microcirculatory deterioration can also be generated. The warning information is used to warn the patient of the deterioration of shock, and warn the patient of possible thrombosis or other adverse symptoms, so that medical staff can intervene in the deterioration of the patient's shock condition early and take preventive measures in time before the patient's condition becomes more serious.

[0082] Figure 5 This is a flow chart of a method for determining the microcirculation status of a patient in the second judgment mode in one of the embodiments of the present application. In one of the embodiments, in the second judgment mode, determining the microcirculation status of the patient based on the ideal body surface skin temperature corresponding to the body surface skin temperature and the ambient temperature may include the following steps S410 to S420.

[0083] Step S410: Determine the ideal skin temperature corresponding to the current ambient temperature according to the corresponding relationship between the ambient temperature and the ideal skin temperature at a specific limb.

[0084] The ideal skin temperature can refer to the average limb skin temperature of healthy individuals under similar environmental conditions. The ideal skin temperature can be determined in advance through literature research or measured on healthy people under specific environments. By predetermining the ideal skin temperature of the skin temperature at a specific limb position of the human body under different temperature environments, a comparison table of environmental temperature-ideal skin temperature can also be established.

[0085] Figure 6 This is a schematic diagram of a comparison table of ambient temperature and ideal skin temperature in one embodiment of the present application, showing the ideal skin temperature of different parts of the human body at different ambient temperatures. Figure 6 It can be seen that different parts of the human body are affected by the environment to different degrees. Among them, the rectum is least affected by the ambient temperature, and the feet are most affected by the ambient temperature. Using the ambient temperature-ideal skin temperature comparison table, the ideal skin temperature at a specific limb position of the patient under the current ambient temperature can be determined more conveniently and quickly.

[0086] Considering that in actual patient monitoring, the patient may be transferred or the temperature of the patient's environment may change significantly. Usually, the temperature of the human extremities is greatly affected by environmental changes, while the temperature of the human body's cavity changes less with the environment. Therefore, if the change trend of the difference between the skin temperature of the patient's specific limb position (such as toes) and the patient's cavity temperature is still compared when the ambient temperature changes greatly, it may lead to inaccurate judgment of the patient's microcirculation changes and draw wrong conclusions. Therefore, in the case of large changes in ambient temperature, the second judgment mode is used to determine the patient's microcirculation state, that is, the patient's current microcirculation state is judged based on the skin temperature at the patient's specific limb position and the ideal skin temperature of the human body at the current ambient temperature.

[0087] Step S420: When the body surface skin temperature is lower than the ideal body surface skin temperature, and a second difference between the ideal body surface skin temperature and the body surface skin temperature is greater than a fourth threshold, it is determined that the patient has insufficient microcirculation.

[0088] The skin temperature at a specific limb of the patient is continuously measured and the ideal skin temperature at a specific limb of the patient under the current ambient temperature is determined, and the actual skin temperature is compared with the ideal skin temperature. When the actual skin temperature at a specific limb position (such as a toe) of the patient is lower than the ideal skin temperature, and the second difference between the ideal skin temperature and the skin temperature is greater than a fourth threshold, it can be determined that insufficient microcirculation has occurred at the specific limb position of the patient. It should be noted that the second difference in the present application refers to the difference between the ideal skin temperature and the skin temperature. Since the skin temperature is lower than the ideal skin temperature at this time, the second difference is also a positive number. The fourth threshold can also be reasonably set according to actual application requirements. Preferably, the fourth threshold can be a value greater than zero.

[0089] In the method for monitoring changes in human microcirculation provided in the present application, in the second judgment mode, it is determined whether the patient has a problem of insufficient microcirculation based on the relationship between the skin temperature at a specific limb position of the patient and the ideal skin temperature corresponding to the ambient temperature. Similarly, after determining that insufficient microcirculation occurs at a specific limb of the patient, early warning information of insufficient microcirculation can also be generated, and the early warning information can be used to warn the patient of worsening shock.

[0090] In one embodiment, see Figure 5 After determining that the patient has insufficient microcirculation, the method may include the following steps S430 to S450.

[0091] Step S430: monitor the change of the second difference within a fourth preset time period.

[0092] When it is determined that the patient has insufficient microcirculation, it is also possible to analyze whether the patient's microcirculation is in a recovery state or a deterioration state based on the changes in the ideal skin temperature at the patient's specific limb position and the current ambient temperature. The feasibility of shock resuscitation of the patient can then be estimated based on the changes in the patient's microcirculation.

[0093] Step S440: When the second difference gradually decreases within the fourth preset time period, it is determined that the microcirculation blood flow of the patient has entered a recovery state.

[0094] Step S450: When the second difference gradually increases within the fourth preset time period, it is determined that the microcirculation blood flow of the patient has entered a deteriorating state.

[0095] The changing trend of the second difference between the ideal body surface skin temperature corresponding to the current ambient temperature and the actual body surface skin temperature at the patient's specific limb can be continuously monitored. A continuity trend change curve of the second difference can also be generated according to the change of the second difference. Based on the continuity trend change curve of the second difference, the change of the second difference can be intuitively understood. When the second difference shows a gradually decreasing trend within the fourth preset time period, it indicates that the microcirculation blood flow at the patient's specific limb has entered a recovery state. When the second difference shows a gradually increasing trend within the fourth preset time period, it indicates that the microcirculation blood flow at the patient's specific limb has entered a deterioration state. Similarly, after determining that the microcirculation blood flow at the patient's specific limb has entered a recovery state or a deterioration state, a corresponding prompt message is generated to facilitate medical staff to understand the patient's condition in a timely manner.

[0096] Figure 7 This is a schematic diagram of a continuous trend change curve of the cavity temperature and the toe temperature in one embodiment of the present application. In this embodiment, Figure 7 Taking the changes in the temperature in the cavity and the temperature of the toes as an example, the second judgment mode used in the present application to judge the microcirculation state of a specific limb of a patient is described. The description is relatively specific and detailed, but it cannot be understood as limiting the scope of the invention patent.

[0097] When the second judgment mode is used to determine the microcirculation state of the patient, at time t9, the patient's toe temperature is less than the ideal toe temperature, and the second difference between the ideal toe temperature and the toe temperature is greater than the fourth threshold value, so it can be judged that the patient has insufficient microcirculation at the toe starting from time t9. In the case of judging that the patient has insufficient microcirculation, the change of the second difference between the ideal toe temperature and the toe temperature is continuously monitored. When it is monitored that the second difference gradually increases in the fourth preset time period between time t9 and time t10, it can be judged that the microcirculation blood flow of the patient has entered a deteriorated state. From time t9 to time t11, the second difference continues to be in a gradually increasing state, so it can be judged that the microcirculation blood flow of the patient is in a continuously deteriorating state. When it is monitored that the second difference gradually decreases in the fourth preset time period between time t11 and time t12, it can be judged that the microcirculation blood flow of the patient has entered a recovery state from time t11.

[0098] It should be understood that, although the steps in the flowcharts of the accompanying drawings of the specification are displayed in sequence as indicated by the arrows, these steps are not necessarily executed in sequence in the order indicated by the arrows. Unless otherwise specified herein, there is no strict order restriction on the execution of these steps, and these steps can be executed in other orders. Moreover, at least a part of the steps in the flowcharts of the accompanying drawings of the specification may include multiple steps or multiple stages, and these steps or stages are not necessarily executed at the same time, but can be executed at different times, and the execution order of these steps or stages is not necessarily sequential, but can be executed in turn or alternately with other steps or at least a part of the steps or stages in other steps.

[0099] Based on the description of the above-mentioned embodiment of the monitoring method for changes in human microcirculation, the present application also provides a monitoring device for changes in human microcirculation. The device may include a system (including a distributed system), software (application), module, component, server, client, etc. using the method described in the embodiment of this specification and a device combined with necessary implementation hardware. Based on the same innovative concept, the device in one or more embodiments provided in the embodiment of the present application is as described in the following embodiments. Since the implementation scheme and method for solving the problem of the device are similar, the implementation of the specific device in the embodiment of this specification can refer to the implementation of the aforementioned method, and the repetitions will not be repeated. As used below, the term "unit" or "module" can implement a combination of software and / or hardware for predetermined functions. Although the device described in the following embodiments is preferably implemented in software, the implementation of hardware, or a combination of software and hardware, is also possible and conceived.

[0100] The present application also provides a device for monitoring changes in human microcirculation. Figure 8 This is a structural schematic diagram of a device for monitoring changes in human microcirculation in one of the embodiments of the present application. In one of the embodiments, the device for monitoring changes in human microcirculation may include a body surface temperature monitoring module 100, an intracavitary temperature monitoring module 200, an ambient temperature monitoring module 300 and a control module 400.

[0101] The body surface temperature monitoring module 100 can be used to monitor the body surface skin temperature of a specific limb of a patient. In some feasible embodiments, the body surface temperature monitoring module 100 may include but is not limited to a surface temperature sensor or an infrared thermometer, which can be used to quickly obtain the skin temperature of the extremities (such as fingers and toes). Preferably, the body surface temperature monitoring module 100 is mainly used to measure the skin temperature of the patient's toes.

[0102] The intracavity temperature monitoring module 200 can be used to monitor the intracavity temperature of the patient. In practical applications, a suitable intracavity temperature monitoring point can be selected according to the specific application, such as the rectum, esophagus or bladder, and the intracavity temperature monitoring module 200 can include a corresponding temperature probe, and the intracavity temperature is measured using the corresponding temperature probe. Preferably, the intracavity temperature monitoring module 200 is mainly used to measure the intracavity temperature at the rectum of the patient.

[0103] The ambient temperature monitoring module 300 can be used to monitor the ambient temperature. In some feasible implementations, the body surface temperature monitoring module 100 can include but is not limited to a dry bulb thermometer, a natural wet bulb thermometer, a black globe thermometer, and the ambient temperature can be measured using ambient temperature measuring instruments such as a dry bulb thermometer, a natural wet bulb thermometer, a black globe thermometer, etc.

[0104] The control module 400 can be connected to the body surface temperature monitoring module 100, the intracavitary temperature monitoring module 200 and the ambient temperature monitoring module 300 respectively. When the control module 400 receives the user's start-up instruction, the control module 400 can automatically select the first judgment mode as the microcirculation judgment mode. Under normal circumstances, the ambient temperature of the patient is stable (for example, in hospital monitoring or emergency on-site monitoring). Therefore, in this embodiment, the first judgment mode can be used as the default mode. After the monitoring device for changes in human microcirculation receives the start-up instruction and starts microcirculation monitoring for the patient, the control module 400 selects the first judgment mode by default to judge the patient's microcirculation state.

[0105] The control module 400 can be used to receive and continuously monitor specific data and changes of information such as ambient temperature, skin temperature at a specific limb of a patient, and intracavitary temperature of a patient. In the first judgment mode, the control module 400 can determine the microcirculation state of the patient based on the skin temperature and intracavitary temperature. When working in the first judgment mode, if the control module 400 determines that the first switching condition is met based on the ambient temperature, the microcirculation judgment mode is switched from the first judgment mode to the second judgment mode.

[0106] In the second judgment mode, the control module 400 can determine the patient's microcirculation state according to the ideal skin temperature corresponding to the skin temperature and the ambient temperature. When working in the second judgment mode, if the control module 400 determines that the second switching condition is met according to the ambient temperature, the microcirculation judgment mode is switched from the second judgment mode to the first judgment mode.

[0107] When the surface temperature monitoring module 100 monitors the surface skin temperature of a patient's specific limb in real time, it can also synchronously generate a continuous change curve of the surface skin temperature of the patient's specific limb. The intracavity temperature monitoring module 200 can also generate a continuous change curve of the patient's intracavity temperature, and the ambient temperature monitoring module 300 can also generate a continuous change curve of the ambient temperature. Further, the control module 400 can determine the change trend of the above temperature information based on the continuous change curves of the surface skin temperature, the intracavity temperature and the ambient temperature, and select a suitable microcirculation judgment mode based on the surface skin temperature of the patient's specific limb test position, the temperature difference with the intracavity temperature, the ambient temperature, the ideal surface skin temperature, and the change in the temperature difference, and determine the changes in the microcirculation blood flow at different positions of the limbs based on the suitable microcirculation judgment mode.

[0108] The present application provides a monitoring device for human microcirculation changes, wherein the body surface temperature monitoring module 100, the intracavity temperature monitoring module 200 and the ambient temperature monitoring module 300 respectively monitor the body surface skin temperature at a specific limb of the patient, the intracavity temperature of the patient and the ambient temperature of the patient in real time. The control module 400 can determine whether to use the first judgment mode or the second judgment mode to judge the microcirculation state of the patient according to the ambient temperature of the patient. In the first judgment mode, the control module 400 determines the microcirculation state of the patient according to the body surface skin temperature and the intracavity temperature; in the second judgment mode, the control module 400 determines the microcirculation state of the patient according to the ideal body surface skin temperature corresponding to the body surface skin temperature and the ambient temperature. By evaluating the microcirculation changes of the patient based on the ambient temperature, the body surface skin temperature at a specific limb of the patient and the intracavity temperature of the patient, the above device can realize non-invasive monitoring of the microcirculation changes of the patient, help to identify the abnormal microcirculation of the patient earlier, and realize the early warning analysis of the patient's condition. Selecting the first judgment mode or the second judgment mode as the microcirculation judgment mode based on the ambient temperature can reduce the influence of the ambient temperature on the evaluation results of the microcirculation state of the patient and improve the accuracy of the evaluation results of the microcirculation state of the patient.

[0109] In one embodiment, the body surface temperature monitoring module 100 may include one or more skin temperature sensors. The skin temperature sensor may be fixed to a specific limb of the patient by means of a thermal insulation material. When the skin temperature sensor is wrapped or adhered to the skin at a specific limb position of the patient using the thermal insulation material, it can be ensured that the temperature of the inner layer of the thermal insulation material is not affected by the outer environmental temperature. That is, when monitoring the skin surface temperature of the patient, using a skin temperature sensor with a thermal insulation material can effectively improve the accuracy and reliability of the measurement, reduce the impact of the external environmental temperature on the sensor reading, ensure that the measured temperature is the true skin surface temperature rather than the temperature of the surrounding environment, and obtain reliable body surface skin temperature data in different environments.

[0110] In some feasible embodiments, the selected thermal insulation material can be made into a sheet or film form and then fixed to the sensor device by adhesive, stitching or molding. For adhesive sensors, the thermal insulation material can also be integrated into the design of medical tapes or patches; for wearable devices, it can be directly embedded in fabrics or plastic shells.

[0111] In one embodiment, when the specific limbs of the patient are the toes of both feet of the patient, the body surface temperature monitoring module determines the highest value of the collected toe temperature as the body surface skin temperature. Considering that the toes are part of the distal limbs, they are more susceptible to changes in vascular microcirculation. In the case of microcirculatory disorders or shock in the patient, the blood perfusion of the feet is usually the first to be affected.

[0112] However, even on the same foot of the same patient, the temperature between different toes may be different. Determining the highest value of the collected toe temperature as the surface skin temperature can better reflect the microcirculatory blood perfusion of the patient. By selecting the highest toe temperature as the surface skin temperature, a more conservative estimate is provided, which helps to prevent underestimation of the patient's body temperature and can more accurately capture the patient's true surface temperature change trend, especially when evaluating the patient's microcirculation status, which helps to detect potential problems earlier and take appropriate intervention measures. At the same time, by selecting the highest toe temperature as the surface skin temperature, it can also avoid the low temperature reading caused by poor contact of individual sensors or other accidental factors that affect the overall judgment, making real-time monitoring more efficient and feasible.

[0113] In one embodiment, the monitoring device for changes in human microcirculation may further include a display module. The display module may be connected to the control module 400, and the display module may be used to display real-time monitoring data such as ambient temperature, the skin temperature of a specific limb of a patient, and the intracavitary temperature of a patient. When the skin temperature monitoring module 100 generates a continuous change curve of the skin temperature of a specific limb of a patient, the intracavitary temperature monitoring module 200 generates a continuous change curve of the intracavitary temperature of a patient, and the ambient temperature monitoring module 300 generates a continuous change curve of the ambient temperature, the display module may also synchronously display the continuous change curves of the skin temperature, the intracavitary temperature, and the ambient temperature, so that the user can more intuitively understand the temperature changes of the patient.

[0114] After the control module 400 determines the microcirculation changes of the patient according to the above-mentioned human microcirculation change monitoring method, the control module 400 can also output different control signals according to the different microcirculation states of the patient, so that the display module can display the corresponding warning information according to the control signal. For example, when the control module 400 determines that the microcirculation insufficiency occurs in a specific limb of the patient, the control module 400 can control the display module to display the warning information of microcirculation insufficiency by outputting a control signal to the display module.

[0115] After the control module 400 determines that the microcirculation blood flow at a specific limb of the patient has entered a recovery state, the display module can also be controlled to display a prompt message of microcirculation recovery to estimate the feasibility of shock resuscitation of the patient. After the control module 400 determines that the microcirculation blood flow at a specific limb of the patient has entered a deterioration state, the display module can also be controlled to display a warning message of microcirculation deterioration. The warning message is used to warn the patient of the deterioration of shock, and warn the patient of possible thrombosis or other adverse symptoms, so that medical staff can intervene in the deterioration of the patient's shock condition early and take preventive measures in time before the patient's condition becomes more serious.

[0116] It is understandable that the various embodiments of the above method in this specification are described in a progressive manner, and the same / similar parts between the various embodiments can be referred to each other, and each embodiment focuses on the differences from other embodiments. For related parts, refer to the description of other method embodiments.

[0117] Those skilled in the art can understand that all or part of the processes in the above-mentioned embodiment methods can be completed by instructing the relevant hardware through a computer program, and the computer program can be stored in a non-volatile computer-readable storage medium. When the computer program is executed, it can include the processes of the embodiments of the above-mentioned methods. Among them, any reference to the memory, database or other medium used in the embodiments provided by the present disclosure can include at least one of non-volatile and volatile memory. Non-volatile memory can include read-only memory (ROM), magnetic tape, floppy disk, flash memory, optical memory, high-density embedded non-volatile memory, resistive random access memory (ReRAM), magnetoresistive random access memory (MRAM), ferroelectric random access memory (FRAM), phase change memory (PCM), graphene memory, etc. Volatile memory can include random access memory (RAM) or external cache memory, etc. As an illustration and not limitation, RAM can be in various forms, such as static random access memory (SRAM) or dynamic random access memory (DRAM). The database involved in each embodiment provided by the present disclosure may include at least one of a relational database and a non-relational database. Non-relational databases may include distributed databases based on blockchains, etc., but are not limited to this. The processor involved in each embodiment provided by the present disclosure may be a general-purpose processor, a central processing unit, a graphics processor, a digital signal processor, a programmable logic unit, a data processing logic unit based on quantum computing, etc., but are not limited to this.

[0118] Each embodiment in this specification is described in a progressive manner, and the same or similar parts between the embodiments can be referred to each other, and each embodiment focuses on the differences from other embodiments. In particular, for the hardware + program embodiment, since it is basically similar to the method embodiment, the description is relatively simple, and the relevant parts can be referred to the partial description of the method embodiment.

[0119] It should be noted that the above-mentioned devices, electronic devices, servers, etc. may also include other implementation methods according to the description of the method embodiments, and the specific implementation methods may refer to the description of the relevant method embodiments. At the same time, the new embodiments composed of the mutual combination of the features between the various methods and device, equipment, and server embodiments still fall within the scope of implementation covered by the present disclosure, and will not be described one by one here.

[0120] In the description of this specification, the description with reference to the terms "some embodiments", "other embodiments", "ideal embodiments", etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic descriptions of the above terms do not necessarily refer to the same embodiment or example.

[0121] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0122] The above-mentioned embodiments only express several implementation methods of the present invention, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the invention patent. It should be pointed out that, for ordinary technicians in this field, several variations and improvements can be made without departing from the concept of the present invention, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the patent of the present invention shall be subject to the attached claims.

Claims

1. A method for monitoring changes in human microcirculation, characterized in that: include: In response to the start instruction, selecting the first judgment mode as the microcirculation judgment mode; In the first determination mode, monitoring the ambient temperature, the skin temperature at a specific limb of the patient, and the intracavitary temperature of the patient; Determining the microcirculation state of the patient according to the skin temperature and the intracavitary temperature; In response to a judgment result that the ambient temperature satisfies a first switching condition, switching the microcirculation judgment mode to a second judgment mode; In the second determination mode, the ambient temperature and the skin temperature of the patient's specific limb are monitored; determining the microcirculation state of the patient according to the body surface skin temperature and the ideal body surface skin temperature corresponding to the ambient temperature; In response to a judgment result that the ambient temperature satisfies a second switching condition, switching to the first judgment mode; Determining the patient's microcirculation state according to the body surface skin temperature and the cavity temperature includes: When the skin temperature is lower than the cavity temperature, and a first difference between the cavity temperature and the skin temperature is greater than a third threshold, it is determined that insufficient microcirculation occurs in the specific limb of the patient; After determining that the patient has insufficient microcirculation, the method further includes: Monitor the change of the first difference within a third preset time period.

2. The method for monitoring changes in human microcirculation according to claim 1, characterized in that: The first switching condition is that a first change value of the ambient temperature within a first preset time period is greater than or equal to a first threshold.

3. The method for monitoring changes in human microcirculation according to claim 1, characterized in that: The second switching condition is that a second change value of the ambient temperature within a second preset time period is less than a second threshold.

4. The method for monitoring changes in human microcirculation according to claim 1, characterized in that: After determining that the patient has insufficient microcirculation, the method further includes: When the first difference gradually decreases within the third preset time period, it is determined that the microcirculation blood flow of the patient enters a recovery state; When the first difference gradually increases within the third preset time period, it is determined that the microcirculation blood flow of the patient has entered a deteriorated state.

5. The method for monitoring changes in human microcirculation according to claim 1, characterized in that: Determining the patient's microcirculation state according to the ideal skin temperature on the body surface and the ambient temperature includes: Determining the ideal skin temperature corresponding to the current ambient temperature according to the corresponding relationship between the ambient temperature and the ideal skin temperature at a specific limb; When the body surface skin temperature is lower than the ideal body surface skin temperature, and a second difference between the ideal body surface skin temperature and the body surface skin temperature is higher than a fourth threshold, it is determined that the patient has insufficient microcirculation.

6. The method for monitoring changes in human microcirculation according to claim 5, characterized in that: After determining that the patient has insufficient microcirculation, the method further includes: Monitoring the change of the second difference within a fourth preset time period; When the second difference gradually decreases within the fourth preset time period, it is determined that the microcirculation blood flow of the patient enters a recovery state; When the second difference gradually increases within the fourth preset time period, it is determined that the microcirculation blood flow of the patient has entered a deteriorated state.

7. A device for monitoring changes in human microcirculation, characterized in that: include: A body surface temperature monitoring module, used to monitor the body surface skin temperature of a patient's specific limbs; An intracavitary temperature monitoring module, used for monitoring the intracavitary temperature of the patient; Ambient temperature monitoring module, used to monitor ambient temperature; a control module, connected to the body surface temperature monitoring module, the intracavity temperature monitoring module and the ambient temperature monitoring module, respectively, for selecting a first judgment mode as a microcirculation judgment mode in response to a start instruction; in the first judgment mode, monitoring the ambient temperature, the body surface skin temperature at a specific limb of the patient and the intracavity temperature of the patient; Determine the patient's microcirculation state according to the body surface skin temperature and the cavity temperature; in response to the judgment result that the ambient temperature meets the first switching condition, switch the microcirculation judgment mode to the second judgment mode; in the second judgment mode, monitor the ambient temperature and the body surface skin temperature of the patient's specific limb; determine the patient's microcirculation state according to the body surface skin temperature and the ideal body surface skin temperature corresponding to the ambient temperature; in response to the judgment result that the ambient temperature meets the second switching condition, switch to the first judgment mode; Determining the microcirculation state of the patient according to the body surface skin temperature and the cavity temperature includes: when the body surface skin temperature is lower than the cavity temperature, and a first difference between the cavity temperature and the body surface skin temperature is greater than a third threshold, determining that insufficient microcirculation occurs in the specific limb of the patient; After determining that the patient has insufficient microcirculation, the change of the first difference within a third preset time period is monitored.

8. The device for monitoring changes in human microcirculation according to claim 7, characterized in that: The body surface temperature monitoring module includes one or more skin temperature sensors, and the skin temperature sensors are fixed to the specific limbs of the patient through thermal insulation protection materials.

9. The device for monitoring changes in human microcirculation according to claim 7, characterized in that: When the patient's specific limbs are the toes of both feet of the patient, the body surface temperature monitoring module determines the maximum value of the collected toe temperature as the body surface skin temperature.

10. The device for monitoring changes in human microcirculation according to claim 7, characterized in that: The monitoring device for human microcirculation changes also includes: A display module, connected to the control module, for displaying the ambient temperature, the skin temperature of a specific limb of the patient, and the intracavitary temperature of the patient; The control module is further used to output different control signals according to different microcirculation states of the patient, and the display module is further used to display early warning information according to the control signal.

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