An anti-dandruff and oil control composition and a method of preparing the same

Abstract

The present application relates to the field of daily chemical products, and discloses a dandruff control and oil control composition and a preparation method thereof.The dandruff control and oil control composition comprises the following components: core components and excipients.The preparation method comprises the following steps: 1) raw material preparation;2) preparation of phase A;3) preparation of phase B;4) mixing;5) homogenization.The dandruff control and oil control composition provided by the present application is from the five dimensions of oil control, inhibition of malassezia, anti-inflammatory, moisturizing and antioxidant, through the addition of oil control components, dandruff control components and conditioning agents as core components, the balance of sebum secretion is maintained, the bacteriostatic effect can be achieved to achieve the dandruff control effect, and the composition components are mild and non-irritating.The preparation method provided by the present application not only improves the production efficiency and is simple in operation process, and is suitable for industrial production.

Description

Technical Field

[0001] This invention relates to the field of daily chemical products, and in particular to an anti-dandruff and oil-controlling composition and its preparation method. Background Technology

[0002] Dandruff, commonly known as seborrheic dermatitis, is a chronic, recurrent, and relatively common scalp problem. Dandruff develops in three stages: the first stage involves scaling; the second stage is accompanied by itching; and the third stage involves erythema, i.e., seborrheic dermatitis. Dandruff is a product of the metabolism of epidermal cells on the scalp. Epidermal cells continuously proliferate and divide on the scalp, moving upwards and gradually forming keratin. The shedding and death of epidermal cells is a normal physiological process, but dandruff causes the epidermal cells to shed at a faster rate than normal. Causes of dandruff include: excessive sebum production, fungal infection (Malassezia), dry scalp, skin inflammation, improper shampooing and care habits, and poor diet and lifestyle habits.

[0003] While anti-dandruff and oil-control products on the market are constantly being updated, most users are still dissatisfied with their dandruff-removing effects. The main reasons are as follows: First, most commercially available anti-dandruff and oil-control products contain anti-dandruff bactericides such as zinc pyrithione (ZPT), piroctone olamine (OCT), ketoconazole, and hemisidine, which are not only highly irritating but also have side effects. Furthermore, some products' surfactant systems are overly cleansing, which can exacerbate scalp inflammation, leading to even worse dandruff-removing effects. Second, current methods for treating dandruff mainly focus on inhibiting Malassezia, but dandruff is influenced by many factors, including scalp microecology, stratum corneum lipids, and the scalp barrier, resulting in poor dandruff-removing and oil-controlling effects from various products.

[0004] More and more people are troubled by dandruff, but existing dandruff-reducing and oil-controlling products are often irritating and offer only one treatment method, leading to consumer dissatisfaction with their effectiveness. This makes the demand for dandruff-reducing and oil-controlling shampoos and conditioners even more urgent. Therefore, researching a gentle dandruff-reducing and oil-controlling composition that inhibits dandruff production from multiple dimensions is of great significance. Summary of the Invention

[0005] To address the aforementioned deficiencies or improvement needs of existing technologies, this invention provides an anti-dandruff and oil-controlling composition and its preparation method. This invention solves the problems of high irritation and poor anti-dandruff and oil-controlling effects found in existing anti-dandruff and oil-controlling products, providing a gentle anti-dandruff and oil-controlling composition that inhibits dandruff production from multiple dimensions. It combines maintaining sebum secretion balance with dandruff removal, and its natural active ingredients are green, gentle, and non-irritating. Adding this composition to shampoo or hair care products can effectively improve the product's anti-dandruff and oil-controlling effects.

[0006] The first aspect of the present invention is to provide a dandruff-removing and oil-controlling composition.

[0007] The second objective of this invention is to provide a method for preparing an anti-dandruff and oil-controlling composition according to the first aspect of this invention.

[0008] To achieve the above objectives, the technical solution adopted by the present invention is as follows:

[0009] A first aspect of the present invention provides an anti-dandruff and oil-controlling composition. The composition comprises the following components, each in weight percentage: core ingredient 38-54%, excipients 46-62%.

[0010] Preferably, the core components include the following components, each component being a percentage by mass in the anti-dandruff and oil-controlling composition: oil-controlling component 15-20%, anti-dandruff component 15-20%, and conditioning agent 8-14%.

[0011] Preferably, the excipients comprise the following components, in the following mass percentages in the anti-dandruff and oil-controlling composition: surfactant 10-15%, emulsifier 1%-2.5%, preservative 0.1%-0.3%, chelating agent 0.02%-0.2%, and deionized water 34.88-44%.

[0012] More preferably, the oil-controlling ingredients are dandelion extract, magnolia bark extract, and tea polyphenols.

[0013] More preferably, the dandruff-removing ingredients are ginger volatile oil and bitter bean grass extract.

[0014] More preferably, the conditioning agent is hydroxypropyltrimethylammonium chloride chitosan, ectoine, and asiaticoside.

[0015] More preferably, the surfactant includes at least anionic surfactants and amphoteric surfactants, wherein the surfactant is at least two of betaine, cocobetaine, cocamidopropyl betaine, sodium lauroyl sarcosinate, sodium cocoyl glycinate, and sodium methyl lauroyl taurate.

[0016] More preferably, the emulsifier includes a water-soluble emulsifier and an oil-soluble emulsifier, wherein the water-soluble emulsifier is at least one of disodium cetearyl sulfosuccinate and sodium stearoyl glutamate; and the oil-soluble emulsifier is at least one of stearyl alcohol polyether-2, stearyl alcohol polyether-21, arachidonic acid glucoside, PEG-100 stearate, glyceryl stearate, cetearyl glucoside, sodium stearoyl glutamate, disodium cetearyl sulfosuccinate, PEG-10 polydimethylsiloxane, PEG-9 polydimethylsiloxane ethyl polydimethylsiloxane, sorbitan oleate, and sorbitan stearate.

[0017] More preferably, the preservative includes at least one selected from methylparaben, propylparaben, phenoxyethanol, sodium benzoate, and potassium sorbate.

[0018] More preferably, the chelating agent is at least one selected from disodium EDTA, trisodium EDTA, tetrasodium EDTA, and pentasodium DTPA.

[0019] More preferably, the mass ratio of the oil-controlling components—dandelion extract, magnolia bark extract, and tea polyphenols—is 1:1:2.

[0020] More preferably, in the anti-dandruff ingredient, the mass ratio of ginger volatile oil to bitter bean extract is 1:1.

[0021] More preferably, in the conditioning agent, the mass ratio of hydroxypropyltrimethylammonium chloride chitosan, ectoine and asiaticoside is 2:1:1.

[0022] More preferably, the mass ratio of the anionic surfactant to the amphoteric surfactant is (0.5-2):1, and the surfactant is a combination of sodium lauroyl sarcosinate and cocamidopropyl betaine.

[0023] A second aspect of the present invention provides a method for preparing an anti-dandruff and oil-controlling composition according to the first aspect of the present invention, the method comprising the following steps:

[0024] 1) Raw material preparation

[0025] S1. Preparation of dandelion extract and magnolia bark extract: Weigh 150g each of dandelion and magnolia bark, place them in round-bottom flasks, add 10 times the amount of water and soak for 2 hours, heat and reflux in a water bath for 45 minutes, filter while hot through a 200-mesh filter cloth and collect the filtrate; add 9 times the amount of water to the residue and reflux for 20 minutes, filter while hot through a 200-mesh filter cloth, combine the filtrates, and concentrate under reduced pressure at 50℃ to 400mL;

[0026] S2. Preparation of ginger volatile oil: Take 200g of medicinal powder, place it in a round bottom flask, add 1800mL of deionized water, first sonicate for 15min, the sonic power is 500W; then extract at 180℃ for 2h, collect the liquid in the volatile oil extractor, centrifuge at 5000 r / min for 5min, and collect the upper liquid.

[0027] S3. Preparation of Sophora flavescens extract: Take 100g of dried Sophora flavescens powder, place it in a round-bottom flask, add an appropriate amount of water, add sodium phosphate buffer solution to adjust the solution pH to 6, then add cellulase (enzyme activity 1500U / g) at a ratio of 1:1000g, heat to 45℃, and enzymatically hydrolyze in a constant temperature water bath for 4.5h. Then add hydrochloric acid at a ratio of 4:1000mL, with a material-to-liquid ratio of 1:16, and extract twice, the first time for 1.5h and the second time for 1h. Filter through a 200-mesh filter cloth, combine the filtrates, and concentrate under reduced pressure at 50℃ to 300mL.

[0028] 2) Preparation of Phase A: Add surfactant, chelating agent, water-soluble emulsifier, oil-controlling component, conditioning agent, deionized water and Sophora flavescens extract to the aqueous phase pot, start stirring, speed 160-200 r / min, heat to 45-55℃, disperse evenly, and use as Phase A;

[0029] 3) Preparation of phase B: Add oil-soluble emulsifier and ginger volatile oil to the oil phase pot, start stirring at 900-960 r / min, heat to 60-70℃, and disperse evenly to obtain phase B;

[0030] 4) Mixing: The A phase from step 2) and the B phase from step 3) are drawn into a high-performance disperser and homogenized under vacuum at high speed at a speed of 8000-9000 r / min. The mixture is stirred until homogeneous and then cooled to obtain mixture I.

[0031] 5) Homogenization: Add preservative to mixture I obtained in step 4 and stir until homogenized for 5-10 minutes until the mixture is uniform, thus obtaining the dandruff-removing and oil-controlling composition.

[0032] Compared with the prior art, the present invention has the following beneficial effects:

[0033] This invention provides an anti-dandruff and oil-controlling composition and its preparation method. The anti-dandruff and oil-controlling composition provided by this invention addresses five dimensions: oil control, Malassezia inhibition, anti-inflammation, moisturizing, and anti-oxidation. By adding oil-controlling ingredients, anti-dandruff ingredients, and conditioning agents, it maintains sebum secretion balance, inhibits bacteria, and achieves an anti-dandruff effect. Moreover, the composition is gentle and non-irritating. For those troubled by oily scalp, this invention uses dandelion extract, magnolia bark extract, and tea polyphenols in synergistic combination to enhance antibacterial and anti-inflammatory effects. By inhibiting the growth of Malassezia, it prevents excessive scalp sebum secretion, balances the scalp's microecological environment, and repairs the scalp's stratum corneum, enabling the composition to exert excellent oil-controlling effects while also relieving itching and soothing the scalp. For those troubled by dandruff and itchy scalp, this invention uses ginger extract and bitter clover extract in combination. Both ginger volatile oil and bitter clover extract have antibacterial, anti-inflammatory, and antioxidant effects. As pure plant ingredients, they are gentle and non-irritating to the human body, and environmentally friendly and pollution-free. For those suffering from dry hair and sensitive scalp, this invention utilizes hydroxypropyltrimethylammonium chloride chitosan, ectoine, and asiaticoside. The combination of ectoine and asiaticoside has a synergistic effect in anti-inflammatory efficacy. Dihydroxypropyltrimethylammonium chloride chitosan has good antioxidant properties, biocompatibility, hygroscopic and moisturizing properties, antibacterial properties, biodegradability, film-forming properties, and non-toxicity. It can not only provide moisturizing and antibacterial effects to the formula without causing allergic reactions, but also improve the stability and bioavailability of other active ingredients in the formula due to its high and low stability.

[0034] This invention provides a method for preparing an anti-dandruff and oil-controlling composition, comprising the following steps: 1) raw material preparation; 2) preparation of phase A; 3) preparation of phase B; 4) mixing; 5) homogenization. The method for preparing dandelion extract and magnolia bark extract provided by this invention was discovered by the inventors through multiple experiments. Adding a water soaking step before extraction and appropriately extending the soaking time improves the oil-controlling effect of the extracted active ingredients. The first extraction uses 10 times the amount of water for 45 minutes, and the second extraction uses 9 times the amount of water for 20 minutes, which improves the efficiency of subsequent heating and reflux extraction, significantly shortening the extraction time. This method can be applied to industrial production, saving production costs. The method for preparing ginger volatile oil provided by this invention uses ultrasonic treatment followed by extraction, making it easier to release the effective components. The extraction time is shortened from the original 4 hours to 2 hours, without affecting the efficacy of ginger volatile oil, thus improving production efficiency. The method for preparing Sophora flavescens extract provided by this invention improves the extraction rate by first enzymatic hydrolysis with cellulase and then acid extraction with hydrochloric acid. Furthermore, this invention adjusts the material-to-liquid ratio to 1:16, which is more in line with actual industrial production practices, and shortens the two acid extraction times from the original 4 hours to 2.5 hours. The preparation method provided by this invention not only improves production efficiency but also simplifies the operation process, making it suitable for industrial production. Detailed Implementation

[0035] The present invention will now be described in further detail with reference to specific embodiments, providing an anti-dandruff and oil-controlling composition and its preparation method, but without limiting the scope of the invention.

[0036] Unless otherwise specified, the materials used in this embodiment are commercially obtained.

[0037] On one hand, the present invention provides an anti-dandruff and oil-controlling composition. The composition comprises the following components, each component being by weight percentage: core ingredient 38-54%, excipients 46-62%.

[0038] The core ingredients include the following components, each component being a percentage by mass in the anti-dandruff and oil-controlling composition: oil-controlling component 15-20%, anti-dandruff component 15-20%, and conditioning agent 8-14%.

[0039] The excipients include the following components, each component in the anti-dandruff and oil-controlling composition by mass percentage: surfactant 10-15%, emulsifier 1%-2.5%, preservative 0.1%-0.3%, chelating agent 0.02%-0.2%, and deionized water 34.88-44%.

[0040] The oil-controlling ingredients are dandelion extract, magnolia bark extract, and tea polyphenols.

[0041] The anti-dandruff ingredients are ginger volatile oil and bitter bean grass extract.

[0042] The conditioning agents are hydroxypropyltrimethylammonium chloride chitosan, ectoine, and asiaticoside.

[0043] The surfactant includes at least anionic surfactants and amphoteric surfactants, and the surfactant is at least two of betaine, cocobetaine, cocamidopropyl betaine, sodium lauroyl sarcosinate, sodium cocoyl glycinate, and sodium methyl lauroyl taurate.

[0044] The emulsifier includes a water-soluble emulsifier and an oil-soluble emulsifier, wherein the water-soluble emulsifier is at least one of disodium cetearyl sulfosuccinate and sodium stearoyl glutamate; and the oil-soluble emulsifier is at least one of stearyl alcohol polyether-2, stearyl alcohol polyether-21, arachidonic acid glucoside, PEG-100 stearate, glyceryl stearate, cetearyl glucoside, sodium stearoyl glutamate, disodium cetearyl sulfosuccinate, PEG-10 polydimethylsiloxane, PEG-9 polydimethylsiloxane ethyl polydimethylsiloxane, sorbitan oleate, and sorbitan stearate.

[0045] The preservative includes at least one of methylparaben, propylparaben, phenoxyethanol, sodium benzoate, and potassium sorbate.

[0046] The chelating agent is at least one of disodium EDTA, trisodium EDTA, tetrasodium EDTA, and pentasodium DTPA.

[0047] The oil-controlling ingredients contain dandelion extract, magnolia bark extract, and tea polyphenols in a mass ratio of 1:1:2.

[0048] In the dandruff-removing ingredients, the mass ratio of ginger volatile oil to bitter bean extract is 1:1.

[0049] In the conditioning agent, the mass ratio of hydroxypropyltrimethylammonium chloride chitosan, ectoine, and hydroxyasiaticoside is 2:1:1.

[0050] Furthermore, the mass ratio of the anionic surfactant to the amphoteric surfactant is (0.5-2):1, and the surfactant is a combination of sodium lauroyl sarcosinate and cocamidopropyl betaine.

[0051] Furthermore, dandelion extract, as a natural plant extract, is rich in various components with antioxidant and anti-inflammatory effects, such as flavonoids and flavonoid compounds. These components can inhibit the production of inflammatory factors and reduce inflammatory damage to tissues. In addition, dandelion extract can reduce inflammatory responses and tissue damage by inhibiting the expression of proteins such as nuclear factor kappa (NF-κB), cyclooxygenase 2 (COX-2), and inducible nitric oxide synthase (iNOS). NF-κB is a signaling molecule in cells that regulates processes such as apoptosis and inflammatory responses; COX-2 and iNOS are enzymes closely related to inflammatory responses. Inhibiting the expression of these proteins can reduce inflammatory responses in the body and promote tissue healing and repair. Studies have shown that when dandelion extract is used in acne treatment products, its components can control excess sebum secretion, thereby achieving an oil-controlling effect.

[0052] Furthermore, Magnolia officinalis refers to the dried bark, root bark, and branch bark of Magnolia officinalis or Magnolia davidii, plants belonging to the genus Magnolia in the family Magnoliaceae. Traditional Chinese medicine believes that Magnolia officinalis has the effects of drying dampness and resolving phlegm, regulating qi and relieving fullness, and is mainly used to treat dampness stagnation in the middle jiao, epigastric fullness and vomiting, diarrhea, food stagnation and qi stagnation, abdominal distension and constipation, and phlegm-dampness cough. Magnolol and its isomers are the most abundant active ingredients in Magnolia officinalis, and their content has become an important quality indicator for the medicinal material. Studies have found that Magnolia officinalis extract has anti-inflammatory effects, combating oxidative stress damage caused by free radicals in the body, and when used in acne treatment products, it has a good oil-controlling effect.

[0053] Furthermore, tea polyphenols (TP) are a major natural product of tea, a complex of polyphenolic compounds mainly composed of catechins, including flavonoids, anthocyanins, and phenolic acids. Tea polyphenols are primarily composed of catechins, which mainly consist of four substances: epicatechin (EC), epigallocatechin (EGC), epigallocatechin gallate (ECG), and epigallocatechin gallate (EGCG), with EGCG being the most abundant catechin. Tea polyphenols possess various biological activities, such as antioxidant activity, anticancer activity, antibacterial activity, and metabolic syndrome regulation activity.

[0054] Among them, tea polyphenols can activate the endogenous antioxidant (Nrf2) pathway and regulate pro-inflammatory and anti-inflammatory signal transduction factors, such as TNF-α, Toll-like receptors, and COX-2, thus playing an anti-inflammatory and immunomodulatory role. These inflammatory factors are related to abnormal sebaceous gland secretion; when their levels are reduced, skin inflammation caused by abnormal sebaceous gland secretion can be effectively improved, thereby indirectly controlling oil production. Studies have shown that the PI3K-AKT-mTORC1 signaling pathway plays an important regulatory role in lipid metabolism, and the EGCG contained in tea polyphenols can inhibit the PI3K-AKT-mTORC1 signaling pathway, thereby reducing sebum secretion. In summary, tea polyphenols have a good oil-controlling effect.

[0055] Furthermore, ginger (Zingiber officinale Roscoe), a perennial herb, has thick roots with a yellowish-white cross-section and a strong pungent aroma. It can be used both as food and medicine. Ginger has the effects of relieving exterior syndromes and dispelling cold, warming the middle jiao and stopping vomiting, and warming the lungs and relieving cough. Ginger has many complex chemical components. Currently, several chemical components have been discovered and identified, basically divided into volatile oil, oleoresin, and diphenylcycloheptanine. The volatile oil and oleoresin are collectively referred to as ginger oil. Among them, gingerol is one of the main effective components of ginger, which can promote blood circulation in the scalp, effectively prevent hair loss, and inhibit scalp itching. The ginger volatile oil selected in this invention has antibacterial, anti-inflammatory, anti-gastric ulcer, and antioxidant physiological activities, and also has a strong aromatic flavor. Studies have shown that ginger volatile oil has a good inhibitory effect on Malassezia, which is a major cause of dandruff.

[0056] Furthermore, *Sophora flavescens* is the dried aerial part of *Sophora flavescens*, a plant belonging to the genus *Sophora* in the legume family. It is mainly distributed in the desert and semi-desert regions of northern China, with abundant resources in Ningxia, Xinjiang, Gansu, and Qinghai. *Sophora flavescens* is bitter and cold in nature, possessing effects such as clearing heat, detoxifying, promoting diuresis, killing parasites, and anti-cancer properties. It is used for diseases such as sore throat, cough due to lung heat, and hepatitis B. For a long time, there have been reports of using *Sophora flavescens* preparations to treat infectious diseases such as cutaneous anthrax and acute bacillary dysentery. Modern pharmacological studies of *Sophora flavescens* have revealed that its active ingredients have strong in vitro antibacterial activity. The main component of *Sophora flavescens* extract is sophoridine, which is one of the more abundant alkaloids contained in *Sophora flavescens*. Studies have found that it has antitumor, antiarrhythmic, anti-inflammatory, antibacterial, and immunosuppressive effects, and it has strong antibacterial activity against *Malassezia*. In summary, as a pure plant-based ingredient, Sophora flavescens extract is safe, green, pollution-free, and inexpensive, and has broad application prospects for long-term antibacterial use.

[0057] Furthermore, chitosan (polyglucosamine (1-4)-2-amino-BD) is odorless and tasteless, and is a product of the N-deacetylation of chitin. Chitosan possesses excellent biodegradability, cell affinity and biological effects, adsorption, film-forming properties, permeability, fiber-forming properties, hygroscopicity, and moisturizing properties. However, chitosan is only soluble in acidic solutions and is insoluble in solutions with a pH greater than 6.5, which has limited its application. Hydroxypropyltrimethylammonium chloride chitosan belongs to quaternized chitosan and is a derivative of chitosan. It is a linear cationic polysaccharide with good water solubility. Quaternized chitosan not only overcomes the problem of poor water solubility of chitosan and retains the advantages of chitosan, but also possesses the properties of quaternary ammonium salts. The hydroxypropyltrimethylammonium chloride chitosan selected in this invention has good antioxidant properties, biocompatibility, hygroscopic and moisturizing properties, antibacterial properties, biodegradability, film-forming properties, and non-toxicity. It can not only provide moisturizing and antibacterial effects to the formula without causing allergic reactions, but also improve the stability and bioavailability of other active ingredients in the formula due to its high and low temperature stability.

[0058] Furthermore, ectoin (also known as tetrahydromethylpyridinecarboxylic acid, Ectoin, EC) is an amino acid derivative, a natural protective component produced by halophilic bacteria in the extracellular layer under high temperature, dryness, strong ultraviolet radiation, and high salinity environments. Ectoin is also a strong hydrophilic substance with a highly electronegative structure, readily forming hydrogen bonds with water molecules. This causes water molecules to orient themselves around it, forming a protective, nourishing, and stable hydrated shell around cells, enzymes, proteins, and other biomolecules. This shell can resist various external damages, thereby reducing the irritation of skin cells by external substances, while also providing long-lasting hydration. In addition, ectoin possesses excellent antioxidant, repair, and anti-inflammatory properties, capable of repairing damaged scalp cells and enhancing cellular immune protection.

[0059] Furthermore, Centella asiatica is the dried whole herb of Centella asiatica, a plant belonging to the genus Centella of the Apiaceae family. It was first recorded in the *Shennong Bencao Jing* (Shennong's Classic of Materia Medica). Its main active components are triterpenoid saponins. Studies have shown that total glycosides from Centella asiatica possess various effects, including anti-ulceration, immunomodulation and apoptosis induction, treatment of skin diseases, and anti-anxiety. The macecassoside (MC) selected in this invention is one of the main components of the triterpenoid saponins in Centella asiatica extract. Studies have shown that macecassoside has anti-inflammatory, antibacterial, moisturizing, antioxidant, and wound-healing promoting functions.

[0060] Furthermore, this invention uses a combination of zwitterionic and anionic surfactants, which can reduce the skin irritation of anionic surfactants and make the product gentler. Preferably, the surfactant is at least two of betaine, cocobetaine, cocamidopropyl betaine, sodium lauroyl sarcosinate, sodium cocoyl glycinate, and sodium methyl lauroyl taurate. Preferably, the surfactant is a combination of sodium lauroyl sarcosinate and cocamidopropyl betaine. After extensive experimentation, this invention found that the combined action of sodium lauroyl sarcosinate and cocamidopropyl betaine in the system can form a tight arrangement in the oil-water phase. The resulting mixed micelles uniformly encapsulate the active functional ingredients and disperse them in the mixed system. The electrorepulsion between the adsorption layer and charged ions is weakened, and the flocculation and precipitation tendency of the composition under temperature changes is significantly suppressed, resulting in a significant improvement in stability. Furthermore, this invention has found that when the mass ratio of sodium lauroyl sarcosinate to cocamidopropyl betaine is (0.5-2):1, the compatibility of the formulation maximizes the antibacterial, anti-inflammatory, dandruff-removing, moisturizing, and soothing effects of the conditioning agents, oil-controlling agents, and dandruff-removing agents.

[0061] Furthermore, the dandruff-reducing and oil-controlling composition provided by this invention addresses five dimensions: oil control, Malassezia inhibition, anti-inflammation, moisturizing, and anti-oxidation. By adding oil-controlling ingredients, dandruff-reducing ingredients, and conditioning agents, it maintains the balance of sebum secretion, inhibits bacteria, and achieves dandruff-reducing effects. Moreover, the composition is gentle and non-irritating.

[0062] On the other hand, the present invention also provides a method for preparing an anti-dandruff and oil-controlling composition, comprising the following steps:

[0063] 1) Raw material preparation

[0064] S1. Preparation of dandelion extract and magnolia bark extract: Weigh 150g each of dandelion and magnolia bark, place them in round-bottom flasks, add 10 times the amount of water and soak for 2 hours. Heat and reflux in a water bath for the first extraction for 45 minutes. Filter the extract while hot through a 200-mesh filter cloth and collect the filtrate. Add 9 times the amount of water to the residue and reflux for the second extraction for 20 minutes. Filter the extract while hot through a 200-mesh filter cloth. Combine the filtrates and concentrate under reduced pressure at 50℃ to 400mL.

[0065] S2. Preparation of ginger volatile oil: Take 200g of medicinal powder, place it in a round bottom flask, add 1800mL of deionized water, first sonicate for 15min, the sonic power is 500W; then extract at 180℃ for 2h, collect the liquid in the volatile oil extractor, centrifuge at 5000 r / min for 5min, and collect the upper liquid.

[0066] S3. Preparation of Sophora flavescens extract: Take 100g of dried Sophora flavescens powder, place it in a round-bottom flask, add an appropriate amount of water, add sodium phosphate buffer solution to adjust the solution pH to 6, then add cellulase (enzyme activity 1500U / g) at a ratio of 1:1000g, heat to 45℃, and enzymatically hydrolyze in a constant temperature water bath for 4.5h. Then add hydrochloric acid at a ratio of 4:1000mL, with a material-to-liquid ratio of 1:16, and extract twice, the first time for 1.5h and the second time for 1h. Filter through a 200-mesh filter cloth, combine the filtrates, and concentrate under reduced pressure at 50℃ to 300mL.

[0067] 2) Preparation of Phase A: Add surfactant, chelating agent, water-soluble emulsifier, oil-controlling component, conditioning agent, deionized water and Sophora flavescens extract to the aqueous phase pot, start stirring, speed 160-200 r / min, heat to 45-55℃, disperse evenly, and use as Phase A;

[0068] 3) Preparation of phase B: Add oil-soluble emulsifier and ginger volatile oil to the oil phase pot, start stirring at 900-960 r / min, heat to 60-70℃, and disperse evenly to obtain phase B;

[0069] 4) Mixing: The A phase from step 2) and the B phase from step 3) are drawn into a high-performance disperser and homogenized under vacuum at high speed at a speed of 8000-9000 r / min. The mixture is stirred until homogeneous and then cooled to obtain mixture I.

[0070] 5) Homogenization: Add preservative to mixture I obtained in step 4 and stir until homogenized for 5-10 minutes until the mixture is uniform, thus obtaining the dandruff-removing and oil-controlling composition.

[0071] Furthermore, the preparation methods of dandelion extract and magnolia bark extract provided by this invention were discovered by the inventors through multiple experiments. Adding a water soaking step and appropriately extending the soaking time before extraction resulted in better oil control of the extracted active ingredients. The first extraction was carried out with 10 times the amount of water for 45 minutes, and the second extraction was carried out with 9 times the amount of water for 20 minutes, which can improve the efficiency of subsequent heating and reflux extraction, greatly shorten the extraction time, and can be applied to industrial production to save production costs.

[0072] Furthermore, the ginger volatile oil preparation method provided by the present invention first uses ultrasonic treatment, and then uses a volatile oil extractor for heating extraction, which makes it easier to release the effective components. The extraction time is shortened from the original 4 hours to 2 hours, and the effect of ginger volatile oil is not affected, thus improving production efficiency.

[0073] Furthermore, the method for preparing Sophora flavescens extract provided by the present invention improves the extraction rate by first hydrolyzing with cellulase and then extracting with hydrochloric acid; and the present invention adjusts the material-liquid ratio to 1:16, which is more in line with the actual industrial production, and shortens the two acid extraction times from the original 4 hours to 2.5 hours.

[0074] The components in Examples 1-3 are configured according to Table 1 below.

[0075] Table 1. Mass percentage of each component in Examples 1-3

[0076]

[0077] The method for preparing the above composition includes the following steps:

[0078] 1. Raw material preparation

[0079] S1. Preparation of dandelion extract and magnolia bark extract: Weigh 150g each of dandelion and magnolia bark, place them in round-bottom flasks, add 10 times the amount of water and soak for 2 hours, heat and reflux in a water bath for 45 minutes, filter while hot through a 200-mesh filter cloth and collect the filtrate; add 9 times the amount of water to the residue and reflux for 20 minutes, filter while hot through a 200-mesh filter cloth, combine the filtrates, and concentrate under reduced pressure at 50℃ to 400mL;

[0080] S2. Preparation of ginger volatile oil: Take 200g of medicinal powder, place it in a round bottom flask, add 1800mL of deionized water, first sonicate for 15min, the sonic power is 500W; then extract at 180℃ for 2h, collect the liquid in the volatile oil extractor, centrifuge at 5000 r / min for 5min, and collect the upper liquid.

[0081] S3. Preparation of Sophora flavescens extract: Take 100g of dried Sophora flavescens powder, place it in a round-bottom flask, add an appropriate amount of water, add sodium phosphate buffer solution to adjust the solution pH to 6, then add cellulase (enzyme activity 1500U / g) at a ratio of 1:1000g, heat to 45℃, and enzymatically hydrolyze in a constant temperature water bath for 4.5h. Then add hydrochloric acid at a ratio of 4:1000mL, with a material-to-liquid ratio of 1:16, and extract twice, the first time for 1.5h and the second time for 1h. Filter through a 200-mesh filter cloth, combine the filtrates, and concentrate under reduced pressure at 50℃ to 300mL.

[0082] 2. Preparation of Phase A: Add surfactant, chelating agent, water-soluble emulsifier, oil-controlling component, conditioning agent, deionized water and Sophora flavescens extract to the aqueous phase pot, start stirring at 200 r / min, heat to 50℃, and disperse evenly to obtain Phase A;

[0083] 3. Preparation of Phase B: Add oil-soluble emulsifier and ginger volatile oil to the oil phase pot, start stirring at 900 r / min, heat to 60℃, and disperse evenly to obtain Phase B;

[0084] 4. Mixing: The A phase from step 2) and the B phase from step 3) are drawn into a high-performance disperser and homogenized under vacuum at high speed at a speed of 8000 r / min. The mixture is stirred until homogeneous and then cooled to obtain mixture I.

[0085] 5. Homogenization: Add preservative to mixture I obtained in step 4 and stir until homogenized for 10 minutes. Homogenize until the mixture is uniform to obtain the dandruff-removing and oil-controlling composition.

[0086] Comparative Example 1

[0087] The difference between Comparative Example 1 and Example 1 is that Comparative Example 1 does not add dandelion extract and magnolia bark extract, but adds tea polyphenols with a content equivalent to that of dandelion extract and magnolia bark extract in Example 1.

[0088] Comparative Example 2

[0089] The difference between Comparative Example 2 and Example 1 is that Comparative Example 2 does not add Magnolia officinalis extract and tea polyphenols, but adds dandelion extract with a content equivalent to that of Magnolia officinalis extract and tea polyphenols in Example 1.

[0090] Comparative Example 3

[0091] The difference between Comparative Example 3 and Example 1 is that Comparative Example 3 does not add dandelion extract and tea polyphenols, but adds magnolia bark extract with a content equivalent to that of dandelion extract and tea polyphenols in Example 1.

[0092] Comparative Example 4

[0093] The difference between Comparative Example 4 and Example 1 is that Comparative Example 4 does not add ginger volatile oil, but adds bitter bean extract with a content equivalent to that of ginger volatile oil in Example 1.

[0094] Comparative Example 5

[0095] The difference between Comparative Example 5 and Example 1 is that Comparative Example 5 does not add Sophora flavescens extract, but adds ginger volatile oil with an amount equivalent to that of Sophora flavescens extract in Example 1.

[0096] Comparative Example 6

[0097] The difference between Comparative Example 6 and Example 1 is that Comparative Example 6 does not add hydroxypropyltrimethylammonium chloride chitosan and asiaticoside, but adds ectoine in an amount equivalent to that of hydroxypropyltrimethylammonium chloride chitosan and asiaticoside in Example 1.

[0098] Comparative Example 7

[0099] The difference between Comparative Example 7 and Example 1 is that Comparative Example 7 does not add ectoine and hydroxypropyltrimethylammonium chloride chitosan, but adds asiaticoside with a content equivalent to that of ectoine and hydroxypropyltrimethylammonium chloride chitosan in Example 1.

[0100] Comparative Example 8

[0101] The difference between Comparative Example 8 and Example 1 is that Comparative Example 8 does not contain asiaticoside and ectoine, but contains hydroxypropyltrimethylammonium chloride chitosan in the same amount as in Example 1.

[0102] Experimental Example 1

[0103] This test case evaluates the safety of the anti-dandruff and oil-controlling compositions prepared in Examples 1-3 and Comparative Examples 1-8, testing the potential for adverse skin reactions in humans. The tests were conducted in accordance with the relevant requirements and methods for "Human Skin Patch Test" as outlined in the "Cosmetic Safety Technical Specifications" (2015 edition).

[0104] I. Experimental Preparation

[0105] 1. Test samples: Anti-dandruff and oil-controlling compositions prepared in Examples 1-3 and Comparative Examples 1-8;

[0106] 2. Subjects: 110 volunteers were selected, half male and half female, aged 20-35 years, without inflammatory skin diseases or highly sensitive constitution; they were divided into 11 groups of 10 people each.

[0107] 3. Test materials: informed consent form for subjects, patch test apparatus (area ≤50 mm², depth approximately 1 mm), hypoallergenic adhesive tape, waterproof marker, patch test ruler, magnifying glass, and skin occlusive patch test record form;

[0108] II. Experimental Procedure

[0109] 1. Clean the skin on the flexor side of the forearm of the test subject, and keep the test site dry;

[0110] 2. Weigh 0.020-0.025g of test sample and place the test sample into the small chamber of the spot tester; the control well is a blank control (without any substance).

[0111] 3. Apply the patch applicator containing the test sample from step 2 to the back or flexed side of the forearm of the subject using hypoallergenic adhesive tape, and gently press it with the palm of your hand to make it evenly adhere to the skin for 24 hours.

[0112] 4. Observation: Skin reaction was observed 30 minutes (after the indentation disappeared), 6 hours, 12 hours, 24 hours and 48 hours after the removal of the test sample spot apparatus, and the observation results were recorded according to the standards in Table 2.

[0113] Table 2. Grading Criteria for Skin Reaction in Closed Patch Tests

[0114]

[0115] III. Test Results

[0116] Human skin occlusive patch test showed that all subjects had negative results and no adverse skin reactions, indicating that the dandruff-reducing and oil-controlling composition prepared in this invention does not cause allergic reactions, is non-irritating, and has high safety.

[0117] Experimental Example 2

[0118] This test example evaluates the physicochemical stability of the anti-dandruff and oil-controlling compositions prepared in Examples 1-3 and Comparative Examples 1-8. The tests were conducted according to the determination methods in standard GB / T 29679-2013.

[0119] I. High Temperature Stability

[0120] The dandruff-reducing and oil-controlling compositions prepared in Examples 1-3 and Comparative Examples 1-8 were placed at 40°C for 48 hours. If no stratification was observed in the composition after returning to room temperature, the high-temperature stability was recorded as "excellent"; if stratification was observed in the composition after returning to room temperature, the high-temperature stability was recorded as "poor".

[0121] II. Low Temperature Stability

[0122] The compositions prepared in Examples 1-3 and Comparative Examples 1-8 for relieving itching, removing dandruff, and controlling oil were placed at -8°C for 48 hours. If no layering was observed after the compositions returned to room temperature, the low-temperature stability was recorded as "excellent"; if layering was observed after the compositions returned to room temperature, the low-temperature stability was recorded as "poor".

[0123] III. Test Results

[0124] The specific experimental results are shown in Table 3.

[0125] Table 3. Evaluation results of physicochemical stability of different test samples

[0126]

[0127] The physicochemical stability evaluation results of the anti-dandruff and oil-controlling compositions prepared in Examples 1-3 and Comparative Examples 1-8 show that, except for Comparative Example 6 which was rated as poor, the evaluation results of the other test samples were all rated as excellent. This indicates that the anti-dandruff and oil-controlling compositions prepared in this invention have good physicochemical stability, in which hydroxypropyltrimethylammonium chloride chitosan plays a key role in the stability of other active ingredients.

[0128] Experimental Example 3

[0129] This experiment evaluates the effectiveness of the dandruff-removing and oil-controlling compositions prepared in Examples 1-3 and Comparative Examples 1-8.

[0130] I. Experimental Preparation

[0131] 1. Subjects: 110 volunteers were selected, 55 men and 55 women, aged 20-50, with problems of dandruff, oily scalp and itchy scalp. They were randomly divided into 11 groups of 10 people each, with half men and half women.

[0132] 2. Test samples: Anti-dandruff and oil-controlling compositions prepared in Examples 1-3 and Comparative Examples 1-8.

[0133] II. Test Methods

[0134] 1. Depending on the thickness of your hair, use 20-50ml each time, once every two days, for two consecutive months;

[0135] 2. Calculate the following indicators for scoring: oil control, dandruff removal, and itch relief; the scoring is based on a 10-point scale, with the highest score being 10 points and the lowest score being 0 points. The average of the scores given by each volunteer is taken.

[0136] III. Test Results

[0137] The specific experimental results are shown in Table 4.

[0138] Table 4 Evaluation results of the effects of different test samples

[0139]

[0140] The physicochemical stability evaluation results of the anti-dandruff and oil-controlling compositions prepared in Examples 1-3 and Comparative Examples 1-8 showed that the anti-dandruff and oil-controlling compositions prepared in Examples 1-3 had better oil-controlling, anti-dandruff, and anti-itch effects, and the overall performance score was better than that of the anti-dandruff and oil-controlling compositions prepared in Comparative Examples 1-8. Among them, Comparative Examples 1-3 had the worst oil-controlling effect, indicating that dandelion extract, magnolia bark extract, and tea polyphenols have good oil-controlling effects, and all three components must be used together to achieve a good oil-controlling effect. Comparative Examples 4 and 5 had the worst anti-dandruff and anti-itch effects, indicating that ginger volatile oil and bitter pea extract have good antibacterial, anti-dandruff, and anti-itch effects, and both are indispensable, with a synergistic effect greater than the sum of their parts. The oil-controlling, anti-dandruff, and anti-itch effects of Comparative Examples 6 and 7 were worse than those of Comparative Example 8, indicating that the high and low temperature stability of hydroxypropyltrimethylammonium chloride chitosan affects the efficacy of other components in the formula.

[0141] Test Example 4

[0142] This experiment evaluates the antibacterial effect of the dandruff-reducing and oil-controlling compositions prepared in Examples 1-3 and Comparative Examples 1-8. The experiment referenced Section 2.1.8.2 of the Ministry of Health's 2002 edition of the "Disinfection Technical Specifications," specifically the inhibition zone test, to determine the antibacterial activity of the test samples against Malassezia. The principle is to utilize the continuous dissolution of the antibacterial agent and its diffusion through agar to form different concentration gradients, thus demonstrating its antibacterial effect. The size of the inhibition zone is used to determine whether the composition possesses antibacterial ability.

[0143] I. Experimental Preparation

[0144] 1. Test samples: Anti-dandruff and oil-controlling compositions prepared in Examples 1-3 and Comparative Examples 1-8;

[0145] 2. Test strain: Malassezia furfur ATCC44344, obtained from Guangdong Provincial Microbial Culture Collection Center;

[0146] 3. Experimental materials: punch, filter paper (5mm diameter round Xinhua No. 1 qualitative filter paper, sterilized by pressure steam, dried at 120℃ for 2 hours, and stored for later use), sterile forceps, sterile cotton swabs, Leeming & Notman culture medium plates and vernier calipers.

[0147] II. Experimental Procedure

[0148] 1. Preparation of antibacterial tablets: Take a number of sterile and dry filter paper sheets, and use sterile tweezers to dip a small amount of the anti-dandruff and oil-controlling composition prepared in Examples 1-3 and Comparative Examples 1-8, spread the filter paper sheets evenly as much as possible, and then place the filter paper sheets flat in a clean sterile Petri dish and let them dry naturally at room temperature to obtain antibacterial tablets.

[0149] 2. Preparation of negative control samples: Take sterile dry filter paper, add sterile distilled water to each paper, and dry it for later use;

[0150] 3. Inoculation of test bacteria: Use a sterile cotton swab to collect a concentration of 5×10⁻⁶ bacteria. 6 Spread the CFU / ml bacterial suspension evenly three times on the surface of a Leeming & Notman agar plate. Rotate the plate 60° after each spread, and finally swab the plate around its edge. Cover the plate and allow it to air dry at room temperature for 5 minutes.

[0151] 4. Sample Placement: Place 4 inhibition strips and 1 negative control strip on each plate, for a total of 5 strips. Use sterile forceps to place the strips onto the plate surface. The centers of each strip should be at least 25 mm apart, and the strips should be at least 15 mm away from the perimeter of the plate. After placement, gently press the strips with sterile forceps to ensure they adhere tightly to the plate surface. Cover the petri dish and incubate upside down in a 32℃ incubator for 7 days.

[0152] 5. Observation results: Measure and record the diameter of the inhibition zone (including the patch) using calipers.

[0153] Note: When measuring the inhibition zone, a uniform and completely sterile inhibition zone should be selected; the diameter should be measured with the outer edge of the inhibition zone as the boundary.

[0154] III. Test Results

[0155] Evaluation guidelines:

[0156] (1) Judgment of antibacterial effect: If the diameter of the inhibition zone is greater than 7 mm, it is judged to have antibacterial effect; if the diameter of the inhibition zone is less than or equal to 7 mm, it is judged to have no antibacterial effect.

[0157] (2) No inhibition zone should be generated in the negative control group; otherwise, the test is invalid.

[0158] No inhibition zones were formed in the negative control group, indicating the validity of this experiment. Specific experimental results are shown in Table 5.

[0159] Table 5 Evaluation results of antibacterial effects of different test samples

[0160]

[0161] The evaluation results of the antibacterial effects of the dandruff-reducing and oil-controlling compositions prepared in Examples 1-3 and Comparative Examples 1-8 show that the dandruff-reducing and oil-controlling compositions prepared in this invention have a good antibacterial effect against Malassezia. Among them, the antibacterial effect of Examples 1-3 is better than that of Comparative Examples 1-8, indicating that the dandruff-reducing and oil-controlling compositions prepared in this invention have a good antibacterial effect against Malassezia. Moreover, the oil-controlling components, dandruff-reducing components and conditioning agents have a synergistic effect, and their combined use can achieve a better antibacterial effect.

[0162] Experimental Example 5

[0163] This experimental example tests the oil-controlling efficacy of the anti-dandruff and oil-controlling compositions prepared in Examples 1-3 and Comparative Examples 1-8. 5α-reductase is a membrane protease dependent on reduced coenzyme II (NADPH) and is an important androgen-metabolizing enzyme in the skin, irreversibly converting testosterone (T) to dihydrotestosterone (DHT). DHT is the most potent androgen, inducing excessive sebum secretion from the sebaceous glands. Therefore, inhibiting 5α-reductase activity can reduce DHT levels, thereby effectively alleviating excessive sebum secretion. Given the relationship between 5α-reductase and sebaceous glands, the inhibitory effect of the test sample on 5α-reductase is usually used to reflect the sebum regulation effect, thus characterizing the oil-controlling efficacy of the test sample.

[0164] I. Preparation of control materials and test samples:

[0165] 1. Test samples: Anti-dandruff and oil-controlling compositions prepared in Examples 1-3 and Comparative Examples 1-8;

[0166] 2. Positive control (finasteride, purity ≥98%): Dilute with anhydrous ethanol to a positive control concentration of 0.1%;

[0167] 3. Negative control: PBS solution.

[0168] II. Experimental Operation Procedures:

[0169] Set up a sample group, a positive control group, a negative control group, and a blank group. Each group should have 3 replicates. Add different reagent solutions to the four groups, shake well, and measure the testosterone content of each group.

[0170] The calculation formula is shown in equation (1):

[0171] Equation (1);

[0172] The specific experimental results are shown in Table 6.

[0173] Table 6. Test results of oil control efficacy of different test samples

[0174]

[0175] The 5α-reductase inhibition rate results of the anti-dandruff and oil-controlling compositions prepared in Examples 1-3 and Comparative Examples 1-8 showed that the 5α-reductase inhibition rate of the positive control was >50%, indicating that the reaction system was effective. The 5α-reductase inhibition rate of the anti-dandruff and oil-controlling compositions prepared in Examples 1-3 and Comparative Examples 1-8 was significantly different from that of the negative control group, indicating that the anti-dandruff and oil-controlling compositions provided by the present invention have a good oil-controlling effect. The 5α-reductase inhibition rate of Examples 1-3 was higher than that of Comparative Examples 1-8, indicating that the combination of the oil-controlling component, anti-dandruff component and conditioning agent of the present invention has a better oil-controlling effect, and the three components work synergistically and are indispensable.

[0176] The embodiments of the present invention have been described in detail above. However, the invention is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of the present invention. Furthermore, the embodiments of the present invention and the features thereof can be combined with each other unless otherwise specified.

Claims

1. An anti-dandruff oil control composition characterized in that, The composition comprises the following components, each in percentage by mass: core component 38-54%, adjuvant 46-62%; The core component comprises the following components, each in percentage by mass in the anti-dandruff and oil control composition: oil control component 15-20%, anti-dandruff component 15-20%, and conditioning agent 8-14%; The adjuvant comprises the following components, each in percentage by mass in the anti-dandruff and oil control composition: surfactant 10-15%, emulsifier 1%-2.5%, preservative 0.1%-0.3%, chelating agent 0.02%-0.2%, and deionized water 34.88-44%; The oil control component is dandelion extract, magnolia bark extract, and tea polyphenol, and the mass ratio of the dandelion extract, magnolia bark extract, and tea polyphenol is 1:1:2; The anti-dandruff component is ginger volatile oil and sophora subprostata extract, and the mass ratio of the ginger volatile oil and sophora subprostata extract is 1:1; The conditioning agent is hydroxypropyltrimonium chloride chitosan, ectoin, and hydroxyl asiatic acid, and the mass ratio of the hydroxypropyltrimonium chloride chitosan, ectoin, and hydroxyl asiatic acid is 2:1:1; The preparation of the dandelion extract and magnolia bark extract comprises: 150 g of dandelion and 150 g of magnolia bark are respectively placed in round-bottom flasks, 10 times the amount of water is added to soak for 2 h, and heating reflux extraction is performed in a water bath for 45 min; while hot, the filtrate is collected by filtering through 200-mesh filter cloth; the residues are added with 9 times the amount of water for reflux extraction for 20 min, and while hot, the filtrate is collected by filtering through 200-mesh filter cloth, and the filtrates are combined and concentrated to 400 mL at 50°C under reduced pressure; The preparation of the ginger volatile oil comprises: 200 g of medicinal material powder is placed in a round-bottom flask, 1800 mL of deionized water is added, ultrasonic treatment is first performed for 15 min at an ultrasonic power of 500 W; and then volatile oil extractors are collected after extraction at 180°C for 2 h, and the upper liquid is collected by centrifugation at 5000 r / min for 5 min; The preparation of the sophora subprostata extract comprises: 100 g of dried sophora subprostata medicinal material powder is placed in a round-bottom flask, an appropriate amount of water is added, a sodium phosphate buffer solution is added to adjust the solution pH to 6, 1:1000 g of cellulase is added, the enzyme activity is 1500 U / g, heating is performed to 45°C, and enzymolysis is performed in a constant-temperature water bath for 4.5 h; then 4:1000 mL of hydrochloric acid is added, the solid-liquid ratio is 1:16, extraction is performed twice, the first time for 1.5 h and the second time for 1 h, the filtrate is collected by filtering through 200-mesh filter cloth, and the filtrates are combined and concentrated to 300 mL at 50°C under reduced pressure.

2. The anti-dandruff and oil control composition according to claim 1, wherein the surfactant at least comprises anionic surfactant and zwitterionic surfactant, and the surfactant is at least two of betaine, cocobetaine, cocamidopropyl betaine, sodium lauroylmethyl amino acid, sodium cocoyl glycinate, and sodium methyl lauroyl taurate. ​ The emulsifier comprises a water-soluble emulsifier and an oil-soluble emulsifier, wherein the water-soluble emulsifier is at least one of disodium cetyl stearyl alcohol sulfosuccinate and sodium stearoyl glutamate; the oil-soluble emulsifier is at least one of stearyl alcohol polyether-2, stearyl alcohol polyether-21, arachidyl alcohol glucoside, PEG-100 stearate, glyceryl stearate, cetyl stearyl glucoside, sodium stearoyl glutamate, disodium cetyl stearyl alcohol sulfosuccinate, PEG-10 dimethicone, PEG-9 polydimethylsiloxane ethyl dimethicone, sorbitan oleate, and sorbitan stearate; The preservative comprises at least one of methylparaben, propylparaben, phenoxyethanol, sodium benzoate, and potassium sorbate; The chelating agent is at least one of disodium EDTA, trisodium EDTA, tetrasodium EDTA, and penta-sodium DTPA.

3. The dandruff control and oil control composition according to claim 2, wherein the mass ratio of the anionic surfactant and the zwitterionic surfactant is (0.5-2):1, and the surfactant is a combination of sodium lauroyl methylcysteinate and cocamidopropyl betaine. The method comprises the following steps:

4. A process for the preparation of an anti-dandruff oil control composition as claimed in any one of claims 1 to 3, characterized in that, 1) raw material preparation: S1, preparation of dandelion extract and magnolia extract; S2, preparation of ginger volatile oil; S3, preparation of sophora extract; 2) preparation of phase A: add the surfactant, chelating agent, water-soluble emulsifier, oil control ingredient, conditioning agent, deionized water, and sophora extract into a water phase kettle, start stirring, heat, and disperse uniformly to obtain phase A; 3) preparation of phase B: add the oil-soluble emulsifier and ginger volatile oil into an oil phase kettle, start stirring, heat, and disperse uniformly to obtain phase B; 4) mixing: draw phase A of step 2) and phase B of step 3) into a high-performance dispersing machine, perform vacuum high-speed homogenization, stir uniformly, stir and cool, and obtain a mixture I; 5) homogenization: add the preservative to the mixture I obtained in step 4), stir uniformly, homogenize for 5-10 min, and perform homogenization treatment until the mixture is uniformly mixed to obtain the dandruff control and oil control composition. The step S1 of preparing the dandelion extract and the magnolia extract comprises: respectively place 150 g of dandelion and 150 g of magnolia in round-bottom flasks, soak in 10 times the amount of water for 2 h, heat in a water bath kettle to reflux extract for 45 min, filter while hot with 200-mesh filter cloth, and collect the filtrate; add 9 times the amount of water to the residue to reflux extract for 20 min, filter while hot with 200-mesh filter cloth, and combine the filtrate and concentrate to 400 mL at 50℃ under reduced pressure.

5. A method of preparing an anti-dandruff oil control composition according to claim 4, characterized in that, The step S2 of preparing the ginger volatile oil comprises: take 200 g of medicinal material powder, place it in a round-bottom flask, add 1800 mL of deionized water, first perform ultrasonic treatment for 15 min at an ultrasonic power of 500 W, then collect the liquid in a volatile oil extractor after extraction at 180℃ for 2 h, and centrifuge at 5000 r / min for 5 min to collect the upper liquid.

6. A method of preparing an anti-dandruff oil control composition according to claim 4, characterized in that, ​ 7. A method of preparing an anti-dandruff oil control composition according to claim 4, characterized in that, The step S3 of preparing the Sophora alopecuroides extract includes: taking 100g of Sophora alopecuroides dried medicinal material powder, placing it in a round-bottom flask, adding an appropriate amount of water, adding a sodium phosphate buffer solution to adjust the solution pH to 6, then adding cellulase at 1:1000g, with an enzyme activity of 1500U / g, heating to 45℃, and constant-temperature water bath enzymolysis for 4.5h, then adding hydrochloric acid at 4:1000ml, with a solid-liquid ratio of 1:16, extracting twice, the first time for 1.5h, the second time for 1h, filtering through 200-mesh filter cloth, and combining the filtrates and reducing the pressure to concentrate to 300ml at 50℃.

8. A method of preparing an anti-dandruff oil control composition according to claim 4, characterized in that, In the step 2), the stirring speed is 160-200r / min, and the heating temperature is 45-55℃.

9. A method of preparing an anti-dandruff oil control composition according to claim 4, characterized in that, In the step 3), the stirring speed is 900-960r / min, and the heating temperature is 60-70℃.

10. A method of preparing an anti-dandruff oil control composition according to claim 4, characterized in that, In the step 4), the stirring speed is 8000-9000r / min.

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