Traditional Chinese medicine for treating soft tissue injury and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine for treating soft tissue injury and a preparation method thereof, and relates to the technical field of traditional Chinese medicine preparations, the traditional Chinese medicine comprises the following components by weight: 7-8 g of dragon's blood, 10-20 g of pseudo-ginseng, 25-35 g of safflower, 20-30 g of frankincense, 20-30 g of myrrh, 0.05-0.15 g of artificial musk, 0.15-0.25 g of artificial bezoar, 0.5-1.5 g of borneol, and 0.5-1.5 g of camphor. According to the traditional Chinese medicine for treating the soft tissue injury and the preparation method, the prescription for treating the acute and chronic soft tissue injury is a proved recipe developed on the basis of folk application experience, the prescription is rigorous, the raw materials are simple and easy to obtain, the preparation is simple and convenient, and an external application mode is adopted; the traditional Chinese medicine composition has the health-care effect of promoting rehabilitation on local swelling pain and muscular limp and numb discomfort caused by acute and chronic soft tissue injuries such as trauma or strain, is safe to apply and exact in effect, achieves ideal effects through mouse experimental research and clinical application, and has the total effective rate of 94.05% on acute and chronic soft tissue injuries shown by clinical research.

Description

Technical Field

[0001] The present invention relates to the technical field of Chinese medicine preparations, and in particular to a Chinese medicine for treating soft tissue injuries and a preparation method thereof. Background Art

[0002] Soft tissue injury belongs to the category of "tendon injury" in traditional Chinese medicine. It is the most common injury suffered by the general public in daily life and the most common disease in clinical orthopedics. Soft tissue injury is caused by external violence directly or indirectly acting on the soft tissue of the human body, which causes muscle injury and collateral damage. Soft tissue injury is divided into acute and chronic. Chronic soft tissue injury is mostly caused by missed treatment, misdiagnosis or improper handling of acute soft tissue injury, or chronic strain causing congestion and edema of tendons and surrounding tissues and other injury inflammation.

[0003] Traditional Chinese medicine believes that when muscles and veins are injured, blood overflows outside the veins, and the blood that has left the meridians gathers locally to form hematomas, and the blood overflows under the skin and becomes cyanotic; the circulation of qi and blood in the local area is restricted, and pain occurs when the blood is blocked; the accumulation of blood causes local redness, swelling, and fever; qi and blood stagnation, and the loss of moisture in the tendons and veins lead to restricted movement and functional disorders; therefore, qi stagnation, blood fatigue, disharmony of the veins, and blockage of the tendons and veins are the pathogenesis of acute tendon injuries, and drugs that activate blood circulation and relieve fatigue should be used directly on the local area to quickly remove the blood fatigue and eliminate swelling and pain as soon as possible;

[0004] The treatment of soft tissue injury is divided into external treatment and internal treatment. Both treatments have been valued by doctors of all generations, and there are many insightful discussions and empirical prescriptions. Among them, external treatment is the most effective method of TCM for treating soft tissue injury. External drugs play an important role in treatment. Because of local application, the drug power can directly reach the injured part, the effect is rapid, and it is easy to use.

[0005] Although existing topical drugs are effective in treating soft tissue injuries, their formulas are not entirely reasonable, and their preparation methods are not ideal, which cannot effectively exert their comprehensive efficacy, resulting in a long course of treatment and slow effects. At the same time, some topical drugs use expensive traditional Chinese medicines, which increases the cost of topical drugs and increases the treatment burden on patients. Therefore, existing topical drugs for treating soft tissue injuries are not ideal enough.

[0006] In order to solve the deficiencies of the prior art, we propose a traditional Chinese medicine for treating soft tissue injuries and a preparation method thereof. Summary of the invention

[0007] The main purpose of the present invention is to provide a traditional Chinese medicine for treating soft tissue injuries and a preparation method thereof, which can effectively solve the problems in the background technology.

[0008] To achieve the above object, the technical solution adopted by the present invention is:

[0009] A traditional Chinese medicine for treating soft tissue injuries, comprising the following ingredients by weight: 7-8g of dragon's blood, 10-20g of notoginseng, 25-35g of safflower, 20-30g of frankincense, 20-30g of myrrh, 0.05-0.15g of artificial musk, 0.15-0.25g of artificial bezoar, 0.5-1.5g of borneol and 0.5-1.5g of camphor.

[0010] Preferably, the Chinese medicine is composed of the following ingredients by weight: 7.5g of Sanguisorba officinalis, 15g of Panax notoginseng, 30g of safflower, 25g of frankincense, 25g of myrrh, 0.1g of artificial musk, 0.2g of artificial bezoar, 1g of borneol, and 1g of camphor. The Chinese medicine is used for preparing muscle relaxing and pain relieving drugs.

[0011] A method for preparing a Chinese medicine for treating soft tissue injury, comprising the following steps:

[0012] S1: Weigh dragon's blood, notoginseng, safflower, frankincense, myrrh, artificial musk, artificial bezoar, borneol and camphor according to weight fraction;

[0013] S2: Grind the dragon's blood, Panax notoginseng, safflower, frankincense and myrrh into coarse powder in the mortar respectively, mix them evenly, add them into a container with 800 ml of ethanol by immersion method, the ethanol concentration is 95%, immerse for 30 days, filter, squeeze the residue, combine the liquid, let it stand for 24 hours, filter, and get the initial synthesis liquid;

[0014] Specifically, the grinding method is adopted, five Chinese medicines, namely, Sanqi, safflower, frankincense and myrrh, are placed in a mortar and ground into coarse powder respectively, and all the powdered Chinese medicines are placed in a container and mixed evenly;

[0015] Then, according to the maceration method under the tincture item of the "Chinese Pharmacopoeia" (Volume 4 of the 2020 edition), a solvent is added to the container, and the solvent is 95% ethanol. During the maceration process, the powdered medicinal materials and 400 ml of ethanol are mixed in the container to form a preliminary liquid. The preliminary liquid is first cold-impregnated, and the container is sealed and placed in a cool place for 14 days, and then hot-impregnated. The preliminary liquid in the container is heated to 70°C and maintained for 2 hours, and then after cooling to 25°C, hot-impregnated for 1 day. After cooling, the preliminary liquid in the container is filtered using a 120-mesh sieve to obtain the first medicinal solution;

[0016] Then, the drug residue is placed in a container, and the same volume and concentration of ethanol is added to the container, and then cold soaking is performed for 14 days. After the cold soaking is completed, the drug residue is squeezed to flow out the squeezed liquid, the squeezed liquid is mixed with the preliminary liquid, and then hot soaked for 1 day. After cooling, it is filtered through a 120-mesh sieve to obtain the second drug solution;

[0017] The first and second drug solutions were mixed evenly, combined, allowed to stand for 24 hours, and filtered through a 120-mesh sieve to obtain an initial synthetic solution; wherein stirring was performed regularly during the immersion period, the immersion time was a total of 30 days, and the solvent was a total of 800 ml of ethanol, 95% concentration of ethanol.

[0018] S3: Add artificial musk and artificial bezoar to a fresh grinder containing 100 ml of ethanol, the ethanol concentration being 75%, grind into fine powder, and then slowly add to the preliminary medicinal solution while stirring to obtain a mixed solution;

[0019] Specifically, the new research body is filled with 100 ml of ethanol, and the ethanol concentration is 75%. Artificial musk and artificial bezoar are added to the new research body, and the artificial musk and artificial bezoar are ground into fine powder. Then, the fine powdered medicinal materials are slowly poured into the initial synthesis liquid while stirring to make the fine powdered medicinal materials and the initial synthesis liquid evenly mixed, so as to obtain a mixed liquid;

[0020] S4: Borneol and camphor are dissolved in a container filled with 50 ml of ethanol, the concentration of ethanol being 75%, to obtain a solution;

[0021] Specifically, 50 ml of ethanol with a concentration of 75% is placed in a container, borneol and camphor are added into the container, and stirred evenly to dissolve the borneol and camphor in the ethanol to obtain a solution.

[0022] S5: The mixed solution and the dissolved solution are mixed and placed in a medicine bottle, 45% ethanol is added to make the volume up to 1000 ml, and the bottle is sealed to obtain the traditional Chinese medicine for treating soft tissue injury.

[0023] Specifically, the mixed liquid and the dissolved liquid are mixed evenly and poured into a medicine bottle with qualified packaging, and then 45% concentration ethanol is added to make up the volume, and the volume is made up to 1000 ml. After sealing, the traditional Chinese medicine for treating soft tissue injuries is obtained, and then it is packaged according to the product packaging specifications, sampled and inspected, and if qualified, it is packed and sealed into boxes and put into storage, and stored in a cool place. At the same time, the finished products sampled at the time of leaving the factory can only be shipped after passing the quality inspection.

[0024] The dosage form of the Chinese medicine preparation for treating soft tissue injuries of the present invention - tincture, is named "muscle-relieving and pain-relieving tincture"; it can also be set as a liniment, spray, ointment or other pharmaceutically acceptable external dosage forms for easy external application to the affected area.

[0025] The pharmacological effects of Chinese medicine of the present invention are as follows:

[0026] Xuejie: ​​sweet, salty, neutral. Enters the heart and liver meridians. Promotes blood circulation and relieves pain, removes blood stasis and stops bleeding, heals sores and promotes tissue regeneration. Used for traumatic injuries, heart and abdominal pain, traumatic bleeding, and sores that do not heal.

[0027] Panax notoginseng: warm, sweet, slightly bitter. Enters the liver and stomach meridians. Nourishes blood, resists inflammation, promotes blood circulation and removes blood stasis. Used to stop bleeding, remove blood stasis, relieve inflammation and relieve pain, and treat injuries from falls.

[0028] Safflower: warm, pungent. Enters the heart and liver meridians. Promotes blood circulation and menstruation, dissipates blood stasis and relieves pain. Used for amenorrhea, dysmenorrhea, lochia retention, chest pain, abdominal pain due to blood stasis, and injuries from falls.

[0029] Frankincense: pungent, bitter, warm. Enters the heart, liver, and spleen meridians. It promotes blood circulation, promotes qi circulation, relieves pain, reduces swelling, and promotes tissue regeneration. It is used for chest pain, heart pain, stomach pain, dysmenorrhea, amenorrhea, postpartum blood stasis, abdominal pain due to abdominal masses, rheumatic pain, muscle spasm, traumatic injuries, carbuncle, ulcers.

[0030] Myrrh: pungent, bitter, neutral. Enters the heart, liver, and spleen meridians. Disperses blood stasis, relieves pain, reduces swelling, and promotes tissue regeneration. Used for chest pain, heart pain, stomach pain, dysmenorrhea, amenorrhea, postpartum blood stasis, abdominal pain due to lumps, rheumatic pain, traumatic injuries, carbuncle, ulcers.

[0031] Artificial bezoar: sweet, cool in nature. Enters the heart and liver meridians. Clears away heat and detoxifies, resolves phlegm and calms convulsions. Used for phlegm-heat delirium, coma and aphasia, acute convulsions in children, sore throat, mouth sores, carbuncles and boils.

[0032] Artificial Musk: Pungent, warm. Enters the heart and spleen meridians. Aromatic and invigorating, dredges the meridians, relieves swelling and relieves pain, activates blood circulation and dredges the menstruation. Used for blood stasis, pain from falls, sores, swelling and sore throat.

[0033] Borneol: slightly cold, pungent and bitter. Enters the heart, spleen and lung meridians. Refreshes the mind, clears away heat and relieves pain, and has antibacterial and anti-inflammatory properties. Used for swollen and painful sores, long-term ulcers that do not heal, red and swollen eyes, pus in the ear canal, sore throat, and sores in the mouth and tongue.

[0034] Camphor: pungent, warm. Enters the heart and spleen meridians. Clears the orifices and removes filth, removes dampness and kills insects, warms and disperses the body to relieve pain. Used to treat skin problems, injuries from falls, and toothaches.

[0035] In the composition of the prescription of the present invention,

[0036] Main drug: Xuejie is sweet and salty in taste, and has the functions of promoting blood circulation, relieving pain, removing blood stasis and stopping bleeding. It is the main drug in the prescription.

[0037] Assistant drugs: Panax notoginseng is sweet and warm, dispersing blood stasis and stopping bleeding, reducing swelling and relieving pain; safflower is pungent and warm, promoting blood circulation and dredges the menstruation, dispersing blood stasis and relieving pain. Panax notoginseng and safflower are both assistant drugs, helping Xuejie to reduce swelling and dredge the meridians.

[0038] Auxiliary drugs: Frankincense and myrrh are used together to promote blood circulation, relieve pain, reduce swelling and promote tissue regeneration; artificial bezoar is sweet and cool, clears away heat and detoxifies. Frankincense, myrrh and artificial bezoar are all adjuvants.

[0039] Auxiliary drugs: Artificial musk is pungent and warm, can open the orifices, dredge the meridians and relieve pain; borneol and camphor are pungent and cold, can open the orifices, dredge the meridians, clear away heat and relieve pain, and at the same time have the property of aromatic movement, and can lead the medicine directly to the affected area. Artificial musk, borneol and camphor are all auxiliary drugs.

[0040] The above nine medicines all follow the compatibility principle of monarch, minister, adjuvant and envoy. The prescriptions are rigorous and adhere to the pathogenesis. They are for external use, which can relax muscles and tendons, relieve swelling and relieve pain. At the same time, when collecting raw and auxiliary materials, the raw and auxiliary materials are inspected and accepted in accordance with the "Chinese Pharmacopoeia" (Volume 1, Volume 2, and Volume 4 of the 2020 edition); the raw and auxiliary materials can only be put into production after being purified and inspected and qualified, and the packaging materials are inspected and accepted according to the company's quality standards and used after passing the inspection.

[0041] Compared with the prior art, the present invention has the following beneficial effects:

[0042] 1. The prescription for treating acute and chronic soft tissue injuries of the present invention is a proven prescription developed based on folk application experience. The prescription has rigorous composition and follows the compatibility principle of monarch, minister, adjuvant and guiding ingredients. The raw materials are simple and easy to obtain, the preparation is simple, the application is safe and the effect is definite. It has development value and clinical application prospects.

[0043] 2. The prescription for treating acute and chronic soft tissue injuries of the present invention is applied externally and can promote the recovery of local bruises, pain, muscle soreness and discomfort caused by acute and chronic soft tissue injuries such as trauma or strain. BRIEF DESCRIPTION OF THE DRAWINGS

[0044] Figure 1 This is a schematic diagram of the preparation of the Chinese medicine for treating soft tissue injury of the present invention; DETAILED DESCRIPTION

[0045] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further explained below in conjunction with specific implementation methods.

[0046] Embodiment 1

[0047] The traditional Chinese medicine for treating soft tissue injury of the present invention consists of the following components by weight: 7g of Sanguisorba officinalis, 10g of Panax notoginseng, 25g of safflower, 20g of frankincense, 20g of myrrh, 0.05g of artificial musk, 0.15g of artificial bezoar, 0.5g of borneol and 0.5g of camphor.

[0048] like Figure 1 As shown, the steps of the preparation method of the traditional Chinese medicine for treating soft tissue injury are as follows: taking Sanguisorba officinalis, Panax notoginseng, safflower, frankincense and myrrh in a mortar are respectively ground into coarse powders, all the coarse powders are mixed, poured into a container and 800ml of 95% ethanol is added, soaked for 30 days, filtered, the residues are squeezed, the liquid medicine is combined, and after standing for 24 hours, filtered, and the filtrate is used for standby; then artificial musk and artificial bezoar are taken, and 100ml of 75% ethanol is added to the new mortar and ground into fine powder, which is slowly added to the above filtrate, and the mixed solution is used for standby; then borneol and camphor are taken and dissolved in a container filled with 50ml of 75% ethanol, and the dissolved solution is used for standby; the mixed solution and the dissolved solution are mixed and placed in a medicine bottle, 45% ethanol is added to make the volume to 1000ml, and the Chinese medicine for treating soft tissue injury is obtained by sealing.

[0049] Embodiment 2

[0050] The traditional Chinese medicine for treating soft tissue injury of the present invention consists of the following ingredients by weight: 7.5g of dragon's blood, 15g of notoginseng, 30g of safflower, 25g of frankincense, 25g of myrrh, 0.1g of artificial musk, 0.2g of artificial bezoar, 1g of borneol and 1g of camphor.

[0051] The preparation method of the traditional Chinese medicine for treating soft tissue injury is the same as that in Example 1.

[0052] Embodiment 3

[0053] The traditional Chinese medicine for treating soft tissue injury of the present invention consists of the following ingredients by weight: 8g of Sanguisorba officinalis, 20g of Panax notoginseng, 35g of safflower, 30g of frankincense, 30g of myrrh, 0.15g of artificial musk, 0.25g of artificial bezoar, 1.5g of borneol and 1.5g of camphor.

[0054] The preparation method of the traditional Chinese medicine for treating soft tissue injury is the same as that in Example 1.

[0055] Experimental studies

[0056] Healthy mice were used to study the drugs in each example, and the effectiveness of the drugs was determined from three aspects: pain, swelling and anti-inflammation. The test results were statistically analyzed using SPSS22.0 software, and the measurement was expressed as mean ± standard deviation. It means that the difference is statistically significant (extremely significant: P < 0.01, significant: P < 0.05) using one-way analysis of variance, as follows;

[0057] Test 1:

[0058] Test subjects: 40 mice were selected, each weighing 20±3g, half male and half female;

[0059] Experimental steps: Depilatory cream was used to remove hair from the hind feet of mice. 40 mice were randomly divided into 4 groups, each with 10 mice. One group was a blank control group, which was not smeared with any drug. The remaining groups were smeared with the drugs of the embodiments of the present invention on the depilatory area, washed and dried the depilatory area, and a cotton swab was dipped in the drug and evenly applied to the depilatory area. The smearing area was 5mm 2 The application amount is 0.5g / head, once a day, and 3 days is a course of treatment. The hair removal area should be cleaned before each application. After three courses of treatment, the pain threshold test is performed using the hot plate method.

[0060] 30min, 60min and 120min after the last administration, the mice were placed on the hot plate, and the time when the mice licked their hind paws was recorded; the pain threshold was the time when the mice licked their hind paws as an indicator, and the temperature range of the hot plate was 55±0.5℃. The statistical results are recorded in Table 1.

[0061] Table 1 Effect of the Chinese medicine of the present invention on pain threshold of mice ( n=10)

[0062]

[0063] Note: Compared with the blank group, **P<0.01

[0064] The results showed that compared with the blank group, the pain threshold of mice was significantly increased after applying the drugs of various embodiments of the present invention, among which the difference between Example 2 and the blank group was significant (P<0.01), so the drugs of the present invention can effectively increase the pain threshold of mice.

[0065] Test 2:

[0066] Test subjects: 40 mice were selected, each weighing 20±3g, half male and half female;

[0067] Experimental steps: 40 mice were randomly divided into 4 groups, each with 10 mice, one of which was a blank control group, and the other groups were smeared with the drugs of the present invention on the right ears of the mice, with the smearing area being 1 cm 2 The application amount was 1g / mouse. The right ear of the mice in the blank group was smeared with an equal amount of normal saline. 30 minutes after the last administration, 0.03ml of xylene was applied to the right ear of the mice to cause inflammation. The left ear was used as a control. The mice were killed 30 minutes after the inflammation. The two ears were overlapped and placed. The round ear pieces were taken out with an 8mm puncher. The weight of the two ear pieces was measured.

[0068] Δt=t 1 -t 2 ;

[0069] Δt is the swelling degree of the mouse ear; t 1 is the weight of the right ear of mice in the same group; t 2 is the weight of the left ear of mice in the same group;

[0070]

[0071] P is the inhibition rate of ear swelling in mice; Δt 0 is the swelling degree of the auricle in the blank group, Δt x is the swelling degree of the embodiment group, X=1, 2, 3..., for example, Δt 1The swelling degree of Example 1; the statistical results are recorded in Table 2.

[0072] Table 2 Effect of the Chinese medicine of the present invention on ear swelling in mice ( n=10)

[0073]

[0074]

[0075] Note: Compared with the blank group, **P<0.01, *P<0.05

[0076] The results show that compared with the blank group, the auricle of mice was significantly reduced after applying the drugs of various embodiments of the present invention, among which Example 2 had a significant difference compared with the blank group (P<0.01), and Example 1 and Example 2 had a significant difference compared with the blank group (P<0.05), so the drugs in the present invention can effectively reduce the swelling of the auricle of mice caused by xylene.

[0077] Test 3:

[0078] Test subjects: Take 20 mice, each weighing 20±3g, half male and half female

[0079] Test steps: Use depilatory cream to remove hair on the side of the mouse's abdomen, and use an impactor (impact force of 2kgm / s) to hit the side of the mouse's abdomen three times in a row, with an impact area of ​​1cm 2 , causing local soft tissue damage on the side of the abdomen of the mice. After the model was successfully established, the mice were divided into 4 groups, with 5 mice in each group. One group was a blank group, without applying the drug, and the other groups were applied with the drugs in the embodiments of the present invention, with an application area of ​​1.5 cm 2 , the application amount was 1 g / mouse, once every 4 hours, for a total of 3 times. 4 hours after the last administration, the blood collection site was cleaned with 70% alcohol, the hind legs of the mice were straightened to make the inguinal vein obvious, a disposable blood collection needle was used to pierce the vein, and blood was slowly drawn. The collected blood was placed in a test tube containing EDTA, and the serum was separated after high-speed centrifugation. The serum was measured according to the instructions of the ELISA kit to measure the levels of interleukin 1β (IL-1β) and interleukin 10 (IL-10), and the statistical results were recorded in Table 3.

[0080] Table 3 Effect of the Chinese medicine of the present invention on anti-inflammatory effects in mice ( n=5)

[0081]

[0082] Note: Compared with the blank group, **P<0.01, *P<0.05

[0083] The results show that: compared with the blank group, after the drugs of various embodiments of the present invention were applied to mice, the IL-1β content level of each embodiment was significantly reduced, and the reduction of IL-1β indicated that the drug had a good anti-inflammatory effect, and the IL-10 content level was significantly increased. The increase in IL-10 can promote the production of anti-inflammatory cytokines. Among them, compared with the blank group, there was a significant difference in Example 2 (P<0.01), and compared with the blank group, there was a significant difference between Example 1 and Example 2 (P<0.05), so the drug in the present invention can effectively reduce the inflammatory response and tissue damage in mice.

[0084] Conclusion: The drugs of the present invention are effective in terms of pain, swelling and anti-inflammation. The drug prepared by mixing the medicinal materials in Example 2 according to the weight fraction ratio is more effective than the drugs prepared in the other two groups of examples.

[0085] Clinical Application

[0086] The Chinese medicine composition of the present invention has achieved good results through clinical application, as follows:

[0087] Cases: 100 typical cases of soft tissue injury were selected, including 63 males and 37 females, aged 15-70 years old, and the time of injury to see a doctor was 15 minutes to 6 hours;

[0088] Condition criteria: The disease is divided into three levels: mild, moderate and severe. There were 29 mild cases, 68 moderate cases and 5 severe cases. The specific classification criteria are as follows: Mild refers to slight local swelling, slight tenderness and free movement; Moderate refers to local swelling and pain, limited daily activities, subcutaneous tenderness and congestion, which does not affect daily work and study; Severe refers to obvious swelling, local persistent severe pain, limited life and work, and obvious subcutaneous congestion.

[0089] Treatment method: using the tincture prepared by the present invention: taking 7.5g of dragon's blood, 15g of Panax notoginseng, 30g of safflower, 25g of frankincense and 25g of myrrh, respectively grinding them into coarse powder in a mortar, mixing all the coarse powders, pouring them into a container and adding 800ml of 95% ethanol, soaking for 30 days, filtering, squeezing the residues, combining the liquid medicine, standing for 24 hours, filtering, and using the filtrate for later use; then taking 0.1g of artificial musk and 0.2g of artificial bezoar, adding 75% ethanol, grinding them into fine powder, and slowly adding them into the above filtrate; then taking 1g of borneol and 1g of camphor, dissolving them in 75% ethanol, adding them, mixing them and placing them in a medicine bottle; adding 45% ethanol to make the volume to 1000ml, and sealing.

[0090] When using, apply once in the morning and evening every day. Clean the affected area before application. One course of treatment is 3 days.

[0091] Efficacy standards: The efficacy is divided into three categories: cured: local pain disappears, swelling, bruises and tenderness subside, and function returns to the pre-injury level; markedly effective: local pain and tenderness are rapidly relieved, swelling and bruises are basically eliminated, and function returns to normal; effective: local pain, tenderness, swelling and bruises subside, and functional activities are significantly restored; ineffective: after three courses of treatment, symptoms and signs have not improved significantly.

[0092] Treatment results: see Table 4.

[0093] Table 4 Treatment of patients with the drugs of the present invention

[0094]

[0095] The results showed that among 102 patients, 85 were clinically treated, 9 were significantly effective, 5 were limited effective, and 1 was ineffective. The significant effective rate was 92.16% and the total effective rate was 94.05%.

[0096] Conclusion: The muscle-relieving and pain-relieving tincture prepared by the medicine of the present invention has a health-care effect of promoting recovery for local bruises and pain, muscle soreness and numbness caused by acute and chronic soft tissue injuries such as trauma or strain, and is safe to use and has a definite effect.

[0097] The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. It should be understood by those skilled in the art that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention to be protected. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A Chinese medicine for treating soft tissue injury, characterized in that: Calculated by weight, the composition comprises: 7-8g of dragon's blood, 10-20g of Panax notoginseng, 25-35g of safflower, 20-30g of frankincense, 20-30g of myrrh, 0.05-0.15g of artificial musk, 0.15-0.25g of artificial bezoar, 0.5-1.5g of borneol and 0.5-1.5g of camphor.

2. A Chinese medicine for treating soft tissue injury according to claim 1, characterized in that: The Chinese medicine is composed of the following ingredients by weight: 7.5g of Sanguisorba officinalis, 15g of Panax notoginseng, 30g of safflower, 25g of frankincense, 25g of myrrh, 0.1g of artificial musk, 0.2g of artificial bezoar, 1g of borneol and 1g of camphor. The Chinese medicine is used for preparing muscle relaxing and pain relieving drugs.

3. A method for preparing a Chinese medicine for treating soft tissue injury according to any one of claims 1 to 2, characterized in that: The specific steps include: S1: Weigh nine medicinal materials according to weight: Dragon's Blood, Panax notoginseng, safflower, frankincense, myrrh, artificial musk, artificial bezoar, borneol and camphor; S2: Grind the dragon's blood, Panax notoginseng, safflower, frankincense and myrrh into coarse powder in the mortar respectively, mix them evenly, add them into a container with 800 ml of ethanol by immersion method, the ethanol concentration is 95%, immerse for 30 days, filter, squeeze the residue, combine the liquid, let it stand for 24 hours, filter, and get the initial synthesis liquid; S3: Add artificial musk and artificial bezoar to a fresh grinder containing 100 ml of ethanol, the ethanol concentration being 75%, grind into fine powder, and then slowly add to the preliminary medicinal solution while stirring to obtain a mixed solution; S4: Borneol and camphor are dissolved in a container filled with 50 ml of ethanol, the concentration of ethanol being 75%, to obtain a solution; S5: The mixed solution and the dissolved solution are mixed and placed in a medicine bottle, 45% ethanol is added to make the volume up to 1000 ml, and the bottle is sealed to obtain the traditional Chinese medicine for treating soft tissue injury.

4. Use of a Chinese medicine for treating soft tissue injury according to claim 2 in preparing a muscle relaxing and pain relieving medicine, characterized in that: The dosage forms of the muscle relaxing and pain relieving medicine include tincture, liniment, spray and ointment.

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