Application of substance specifically combined with NSE protein or coding gene thereof in preparation of ARN diagnosis product or prognosis product

By detecting the level of NSE protein in aqueous humor and using substances that specifically bind to NSE protein, the problem of early diagnosis of acute retinal necrosis is solved, the accuracy of diagnosis and timeliness of treatment are achieved, and the prognosis evaluation of patients is improved.

CN119716058AActive Publication Date: 2025-03-28EYE & ENT HOSPITAL SHANGHAI MEDICAL SCHOOL FUDAN UNIV
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Patent Information

Application Number
CN202411823045.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-12
Publication Date
2025-03-28
Estimated Expiration
2044-12-12

AI Technical Summary

Technical Problem

The prior art is difficult to accurately diagnose acute retinal necrosis (ARN) in the early stage, resulting in a high misdiagnosis rate and untimely treatment, which affects the prognosis.

Method used

By detecting the level of NSE protein in aqueous humor, using substances that specifically bind to NSE protein or its gene encoding, to prepare diagnostic or prognostic products to help diagnose ARN early and evaluate the severity of the disease.

Benefits of technology

The objective accuracy of early diagnosis of ARN was achieved, and correct treatment measures were taken in a timely manner, reducing the risk of retinal detachment and blindness, and improving the accuracy of prognostic assessment.

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Abstract

The invention relates to the field of medicine, in particular to application of a substance specifically combined with NSE protein or a coding gene thereof to preparation of an ARN diagnosis product or a prognosis product. By detecting the NSE protein or the encoding gene thereof, optic neuropathy caused by acute retinal necrosis can be informed, and doctors can recognize ARN diseases earlier, so that proper medical intervention can be implemented quickly. Therefore, the risk of retinal abscission and visual loss can be remarkably reduced, clinical doctors can be assisted in accurately evaluating the severity of the illness state and predicting the possibility of visual recovery, and individuation and precision of treatment can be promoted. In addition, by avoiding unnecessary medicine use and medical resource waste, economic benefits are brought, and both the patient and the society are benefited.
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