Classification system and method based on efficacy of Chinese patent medicine

Abstract

The invention discloses a Chinese patent medicine efficacy-based classification system and method, and relates to the technical field of medicine data management, and the technical scheme is characterized in that names and dosages of medicinal materials are collected, basic attributes of medicinal properties, medicinal flavors and channel tropism of the medicinal materials are determined, and a medicinal flavor compatibility structure is determined by analyzing interaction among the medicinal materials and calculating a dosage ratio; according to the traditional Chinese medicine theory of the decoction meridian diagram, the main efficacy category of the Chinese patent medicine is determined by combining the medicine compatibility and the dosage ratio, on this basis, a standardized classification system is formulated, the Chinese patent medicine is classified according to the efficacy, and the information is displayed in a graphical form by using a visualization tool, so that a user can understand and use the information conveniently.

Description

Technical Field

[0001] The present invention relates to the technical field of medical data management, and more specifically, to a classification system and method based on the efficacy of Chinese patent medicines. Background Art

[0002] The technical background of the classification system and method of the efficacy of Chinese patent medicine mainly involves the integration of traditional Chinese medicine theory, pharmacological research and modern scientific and technological means. As an important part of the Chinese medicine system, the efficacy of Chinese patent medicine is usually based on the compound compatibility of multiple medicinal materials, reflecting the holistic view, syndrome differentiation and treatment and personalized treatment concept of Chinese medicine. However, with the development of modern medicine, the vague expression of the efficacy of traditional Chinese medicine, the complexity of the compatibility rules and the unclear mechanism of efficacy have brought certain difficulties to its clinical application and international promotion. Therefore, in order to meet the needs of modern clinical and scientific research, it is necessary to develop a scientific and systematic classification method to standardize and quantify the efficacy of Chinese patent medicine. Such a classification system can not only improve the efficiency of the research and development and application of Chinese patent medicine, but also enhance its recognition in the international medical community and promote the modernization of Chinese medicine.

[0003] In the existing technology, the traditional classification of the efficacy of Chinese patent medicine mainly relies on the classical theories of traditional Chinese medicine, such as the compatibility principle of "monarch, minister, assistant, and messenger", the theory of five flavors and meridians, and the theory of four qi and five flavors. Such classification methods are mainly based on the functional properties of Chinese medicinal materials and their adaptability to different diseases. However, this experience-based classification method lacks sufficient objective standards and is difficult to meet the quantitative needs of modern medicine. With the development of information technology, more and more researchers have begun to try to introduce modern technology into the classification of Chinese patent medicines. For example, with the help of big data, artificial intelligence and bioinformatics technology, we can start from the chemical composition, pharmacological effects and clinical data of Chinese medicines, explore the correlation between Chinese patent medicines, and build a more scientific classification system. At present, some more advanced systems have adopted a combination of symptoms, pharmacology and molecular mechanisms to classify Chinese patent medicines. Some studies have also introduced network pharmacology and genomics to analyze the multi-target and multi-level efficacy mechanisms of Chinese medicines. However, the existing technology still faces many challenges in data standardization, interdisciplinary integration and the accuracy of efficacy classification, which need to be further optimized and broken through.

[0004] The classification of the efficacy of Chinese patent medicines is the premise of rational drug use and pharmaceutical management. The current classification of the efficacy of Chinese patent medicines is often based on the functional description of the Chinese patent medicine instructions, which is carried out by experts based on experience and is highly subjective. The problems with this classification are:

[0005] (1) The number of categories is uncertain. Antipyretics can be divided into two types: pungent-warm antipyretics and pungent-cool antipyretics. They can also be divided into four types: pungent-warm antipyretics, pungent-cool antipyretics, antipyretics that relieve summer heat, and antipyretics that strengthen the body.

[0006] (2) The same Chinese patent medicine may be classified into different efficacy categories, which may cause confusion in the rational use of the medicine in clinical practice. Summary of the invention

[0007] The purpose of the present invention is to provide a classification system and method based on the efficacy of Chinese patent medicines to solve the problems of inconsistent classification standards and classification results in the prior art.

[0008] The above technical objectives of the present invention are achieved through the following technical solutions: a classification system based on the efficacy of Chinese patent medicines, including a formula analysis module, a medicine flavor compatibility module, an efficacy determination module, a classification module and a visualization display module;

[0009] The formula analysis module is responsible for detailed analysis of the formula of the Chinese patent medicine, including identifying and recording the name, medicinal properties, medicinal taste, meridians and role of each medicinal material in the formula;

[0010] The drug flavor compatibility module analyzes the drug flavor compatibility relationship of each medicinal material, and calculates the drug flavor compatibility structure and the drug dosage ratio structure according to the medicinal flavor and dosage of the medicinal material;

[0011] The efficacy determination module determines the main efficacy categories of the Chinese patent medicine in combination with the decoction meridian diagram theory. According to the drug flavor compatibility structure and drug dosage ratio structure, the system will define the efficacy of the Chinese patent medicine;

[0012] The classification module classifies the Chinese patent medicines into corresponding efficacy categories according to their efficacy categories;

[0013] The visual display module is responsible for displaying the formula information, drug compatibility, and efficacy category of the Chinese patent medicine to the user in a graphical manner.

[0014] The present invention is further configured such that: the formula analysis module can also automatically analyze the medicinal material ingredients and establish a property file of the medicinal material by inputting the formula information of the Chinese patent medicine.

[0015] The present invention is further configured as follows: the compatibility relationship of the medicinal flavors includes but is not limited to one of mutually complementary, mutually usable, mutually fearful, and mutually antagonistic.

[0016] The present invention is further configured as follows: the classification module establishes a hierarchical structure of efficacy categories, allowing users to query and filter according to different classification standards.

[0017] Another object of the present invention is a classification method based on the efficacy of Chinese patent medicines, comprising the following steps:

[0018] S1: Collect the formula data of Chinese patent medicines and record the properties of each medicinal material, then conduct a compatibility analysis of the medicinal flavors to determine the ratio structure and conversion ratio of the medicinal flavors;

[0019] S2: Apply the TCM theory of Tangye Jingfatu combined with the results of medicinal taste analysis to determine the efficacy category of Chinese patent medicines;

[0020] S3: Formulate classification standards and classify Chinese patent medicines to establish a systematic classification system;

[0021] S4: Visual display is achieved through drawing charts to help users intuitively view the information of medicinal materials and efficacy.

[0022] The present invention is further configured as follows: the properties of each medicinal material in step S1 include but are not limited to medicinal properties, medicinal taste, meridians, and functions in the prescription.

[0023] The present invention is further configured as follows: the visual display in step S4 includes the medicinal flavor compatibility structure, dosage ratio and efficacy category of the Chinese patent medicine.

[0024] By adopting the above technical scheme, the present invention introduces an automated formula analysis module and a drug compatibility module to systematically analyze the medicinal material properties and compatibility relationships of Chinese patent medicines, thereby forming a unified classification standard based on objective pharmacological data and the theory of Tangye Jingfatu. This standardized process significantly improves the repeatability of classification, reduces human errors, and ensures the consistency of classification results; the system of the present invention uses the theory of Tangye Jingfatu in traditional Chinese medicine in the efficacy determination module, combined with the analysis of the drug compatibility structure and the dosage ratio, to scientifically define the efficacy category of Chinese patent medicines. This method of combining modern information technology with traditional Chinese medicine theory not only enhances the accuracy of classification, but also makes the definition of efficacy more scientific and systematic, and enhances the application value of Chinese patent medicines in the modern medical system;

[0025] The visualization display module of the present invention displays the formula information, drug compatibility structure and efficacy category of medicinal materials through graphical means, helping users to intuitively understand the efficacy and composition of Chinese patent medicines. In addition, the hierarchical structure established in the classification module allows users to flexibly query and filter according to different classification criteria to adapt to different demand scenarios. This flexibility not only improves the user experience of the system, but also provides strong auxiliary support for the research and clinical application of traditional Chinese medicine.

[0026] In summary, the present invention has the following beneficial effects:

[0027] 1. The present invention effectively reduces the influence of subjective factors through systematic processes and standardized classification methods, ensuring that the results of the classification of the efficacy of Chinese patent medicines are more accurate and consistent; the present invention also uses traditional Chinese medicine theories such as Tangye Jingfatu to guide the classification process, and combines modern information technology for in-depth analysis, thereby improving the scientificity and practicality of the classification, and laying a solid foundation for the modern application of Chinese patent medicines; the present invention uses a visual display module so that users can intuitively understand the medicinal material information and efficacy classification. The flexible query and screening functions provided by the system meet diverse needs, improve the practicality of the system and the convenience of user operation, and contribute to Chinese medicine research and clinical practice. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1 Schematic diagram of classification results of an example in an embodiment of the present invention. DETAILED DESCRIPTION

[0029] The following is combined with Figure 1 The present invention is described in further detail.

[0030] Embodiment 1: A classification system based on the efficacy of Chinese patent medicines, comprising a formula analysis module, a medicine flavor combination module, an efficacy determination module, a classification module and a visualization display module;

[0031] Formula analysis module: In this module, the user first inputs the formula information of the Chinese patent medicine. The system automatically identifies the name, medicinal properties, medicinal taste, meridians of each medicinal material and its specific role in the prescription. Through automatic parsing, the system establishes detailed medicinal material attribute files, which include not only the basic attributes of the medicinal materials, but also the relationships between the medicinal materials. These attribute information provides a reliable data basis for the subsequent analysis steps, ensuring the accurate identification and analysis of drug characteristics.

[0032] Drug compatibility module: The core function of this module is to calculate the compatibility structure and dosage ratio of the drugs by analyzing the compatibility relationship and dosage of the drugs. By calculating the drug compatibility and dosage ratio structure, the system determines the interaction effects between the drugs, such as mutual necessities (enhancing efficacy), mutual use (assisting efficacy), mutual fear (avoiding disadvantages) and mutual killing (eliminating toxic side effects). These relationships determine the complementary and regulatory effects of the drugs in the overall prescription, laying the foundation for the determination of efficacy.

[0033] Efficacy determination module: This module combines traditional Chinese medicine theory, especially the "Tangye Jingfa Diagram", to scientifically determine the main efficacy categories of Chinese patent medicines. By analyzing the drug compatibility structure and its corresponding drug dosage ratio, the system can define the efficacy category of each Chinese patent medicine. Since this process is based on systematic theory and precise data analysis, the scientificity and accuracy of the efficacy definition are ensured. For example, a prescription can be clearly classified as "clearing heat and detoxifying" or "activating blood circulation and removing blood stasis".

[0034] Classification module: The efficacy categories of Chinese patent medicines determined by the above modules will be classified into a pre-established hierarchical classification structure. Users can flexibly query and filter according to different standards (such as efficacy, functional indications, etc.), which makes the system highly flexible and applicable, not only simplifying the complex Chinese patent medicine information management process, but also enabling users to quickly obtain the required information according to specific needs.

[0035] As an important part of the interaction between the system and users, the visualization module displays the formula information, compatibility relationship and efficacy category of Chinese patent medicines in an intuitive graphical way. This visualization not only improves the readability of information display, but also helps users better understand the complex relationship between medicinal materials and efficacy information, improving the operability of the system and user experience.

[0036] Embodiment 2: A classification method based on the efficacy of Chinese patent medicines: comprising the following steps:

[0037] S1: Collect the formula data of Chinese patent medicines and record the properties of medicinal materials;

[0038] First, the system records the key attributes of each medicinal material by inputting the formula data of Chinese patent medicine. These attributes include but are not limited to the medicinal properties of the medicinal materials (cold, hot, warm, cool, etc.), the taste of the medicinal materials (five tastes such as pungent, sweet, bitter, sour, and salty), the meridians (that is, the medicinal materials act on specific organs or meridians of the human body, such as the lung meridian, liver meridian, etc.) and the specific role of the medicinal materials in the prescription (such as the different roles of monarch medicine, minister medicine, adjuvant medicine, and messenger medicine), which provides the necessary basic data for the subsequent drug flavor compatibility and efficacy determination. To ensure the comprehensiveness and accuracy of the medicinal material data, the system can also retrieve the corresponding standard data from the existing traditional Chinese medicine database to automatically complete the supplement of the medicinal material attributes. For each medicinal material, the system can further record its usage to ensure that the dosage information is accurate for subsequent analysis.

[0039] S2: Apply the TCM theory of Tangye Jingfatu combined with the results of medicinal taste analysis to determine the efficacy category of Chinese patent medicines;

[0040] After collecting the medicinal material information, the system will conduct an in-depth analysis of the drug compatibility results in combination with the TCM theory of Tangye Jingfatu. Tangye Jingfatu is a systematic TCM theoretical tool used to analyze and summarize the pharmacological effects of prescriptions and determine the efficacy of prescriptions through the interaction between medicinal flavors. This theory combines the characteristics of the medicinal flavors such as pungent, sweet, bitter, sour, and salty, as well as the medicinal properties (cold, hot, warm, and cool) and meridian information to derive the main efficacy categories of the prescription.

[0041] S3: Formulate classification standards and classify Chinese patent medicines to establish a systematic classification system;

[0042] According to the above efficacy analysis results, the system classifies Chinese patent medicines into preset efficacy categories. In this process, the system will use the set classification standards, such as classifying according to the main functions of Chinese patent medicines (such as clearing away heat and detoxifying, replenishing qi and nourishing blood, resolving phlegm and relieving cough, etc.) or the types of diseases treated (such as colds, coughs, liver diseases, etc.). In addition, the classification system has a hierarchical structure, allowing users to perform multi-level queries based on different classification standards. For example, users can screen and classify layer by layer according to disease type, drug function, main symptoms, etc., to ensure the flexibility and adaptability of the classification system.

[0043] S4: Visual display is achieved by drawing charts to help users intuitively view the medicinal materials and efficacy information;

[0044] Finally, the system uses charts to visually display the medicinal material information, flavor combination structure, dosage ratio and efficacy category of Chinese patent medicines to users.

[0045] Example: Yixinshu Pills is a Chinese patent medicine included in the Chinese Pharmacopoeia, which has the effects of invigorating qi and restoring pulse, promoting blood circulation and removing blood stasis, and nourishing yin and promoting body fluid. Its formula compatibility structure and efficacy are determined based on the analysis of the compatibility relationship of medicinal materials and the dosage ratio. The following is a detailed analysis of the compatibility structure of medicinal materials, the dosage ratio structure and its efficacy of the prescription using the classification system based on the efficacy of Chinese patent medicines of the present invention.

[0046] 1. Analysis of drug compatibility structure

[0047] The formula of Yixinshu Pills contains the following medicinal materials and their medicinal properties:

[0048] Ginseng: sweet, salty;

[0049] Ophiopogon japonicus: acid;

[0050] Astragalus: sweet, pungent;

[0051] Schisandra: sour;

[0052] Salvia miltiorrhiza: salty, bitter;

[0053] Chuanxiong: salty, spicy;

[0054] Hawthorn: sour, spicy;

[0055] According to the classification of medicinal flavors, we can classify the medicinal materials in the prescription according to the medicinal flavors:

[0056] Salty herbs: ginseng (salty), salvia miltiorrhiza (salty), chuanxiong (salty);

[0057] Sour herbs: Ophiopogon japonicus (sour), Schisandra chinensis (sour), Crataegus pinnatifida (sour);

[0058] Sweet herbs: ginseng (sweet), astragalus (sweet);

[0059] Spicy drugs: Astragalus (spicy), Chuanxiong (spicy), Crataegus (spicy).

[0060] Therefore, the compatibility structure of Yixinshu Pills can be summarized as "two salty, three sour, and two sweet." In terms of quantity, sour drugs are the main ones, and salty and sweet drugs are the auxiliary ones, forming the main framework of the compatibility relationship.

[0061] 2. Analysis of drug dosage ratio structure

[0062] The specific dosage of each herbal material is as follows: ginseng: 300g, ophiopogon: 300g, astragalus: 300g, schisandra: 200g, salvia: 400g, chuanxiong: 200g, hawthorn: 300g;

[0063] According to the medicinal properties of the medicinal materials, we can calculate the total amount of each medicinal flavor:

[0064] Salty herbs (salty herbs from Salvia miltiorrhiza, Chuanxiong, and ginseng): 600g;

[0065] Sour herbs (Ophiopogon japonicus, Schisandra chinensis, Crataegus pinnatifida): 800g;

[0066] Sweet medicine (sweetness in ginseng and astragalus): 600g.

[0067] Therefore, the dosage ratio of Yixinshu Pills is "3 salty: 4 sour: 3 sweet", that is, salty medicine accounts for 30%, sour medicine accounts for 40%, and sweet medicine accounts for 30%. This ratio structure is also mainly sour, with salty and sweet as auxiliary.

[0068] 3. Determination of efficacy

[0069] According to the theory of "Tangye Jingfatu" and the analysis of medicinal flavor, the main effects of Yixinshu Pills can be derived from the tonic effect of the medicinal flavor:

[0070] Salty medicine (the salty in Salvia miltiorrhiza, Chuanxiong and ginseng): has the effect of nourishing the heart and promoting blood circulation. In particular, the salty taste of Chuanxiong and Salvia miltiorrhiza helps promote blood circulation, promote blood circulation and remove blood stasis, and is suitable for the treatment of cardiovascular diseases.

[0071] Sour medicines (Ophiopogon japonicus, Schisandra chinensis, Hawthorne): Sour taste nourishes the lungs and yin, and has the effects of promoting fluid production and moistening the lungs. In particular, Schisandra chinensis and Ophiopogon japonicus have a good effect on nourishing yin, promoting fluid production and enhancing immunity.

[0072] Sweet medicines (the sweet taste in ginseng and astragalus): The sweet taste replenishes Qi and is mainly used to nourish the spleen and replenish Qi, enhance the body's immunity and support physical recovery. The sweet taste of astragalus and ginseng can improve heart function and regulate the overall Qi and blood circulation.

[0073] Therefore, according to the efficacy of the medicinal flavor, the main efficacy of Yixinshu Pills is determined to be tonifying the heart, and also tonifying the lungs and spleen. The specific efficacy is as follows:

[0074] Promoting blood circulation and removing blood stasis: Mainly salty medicines, Chuanxiong and Salvia miltiorrhiza have obvious blood circulation effects and are suitable for the treatment of cardiovascular and cerebrovascular diseases.

[0075] Invigorating Qi and Nourishing Yin: With sour and sweet herbs as supplements, Ophiopogon japonicus and Schisandra chinensis nourish Yin and produce body fluid, Astragalus and ginseng replenish Qi and aid the heart, which helps to strengthen the body and prevent symptoms of weakness and deficiency of Qi and blood.

[0076] 4. Display of Visual Charts

[0077] In order to more intuitively demonstrate the drug compatibility and efficacy structure of Yixinshu Pills, a graphical visualization can be used. The results are shown in the attached figure. Figure 1 shown.

[0078] This specific embodiment is merely an explanation of the present invention and is not a limitation of the present invention. After reading this specification, those skilled in the art may make non-creative modifications to the present embodiment as needed. However, as long as they are within the scope of the claims of the present invention, they are protected by the patent law.

Claims

1. A classification system based on the efficacy of Chinese patent medicines, characterized by: It includes formula analysis module, medicinal flavor combination module, efficacy determination module, classification module and visual display module; The formula analysis module is responsible for detailed analysis of the formula of the Chinese patent medicine, including identifying and recording the name, medicinal properties, medicinal taste, meridians and role of each medicinal material in the formula; The drug flavor compatibility module analyzes the drug flavor compatibility relationship of each medicinal material, and calculates the drug flavor compatibility structure and the drug dosage ratio structure according to the medicinal flavor and dosage of the medicinal material; The efficacy determination module determines the main efficacy categories of the Chinese patent medicine in combination with the decoction meridian diagram theory. According to the drug flavor compatibility structure and drug dosage ratio structure, the system will define the efficacy of the Chinese patent medicine; The classification module classifies the Chinese patent medicines into corresponding efficacy categories according to their efficacy categories; The visual display module is responsible for displaying the formula information, drug compatibility, and efficacy category of the Chinese patent medicine to the user in a graphical manner.

2. A classification system and method based on the efficacy of Chinese patent medicines according to claim 1, characterized in that: The formula analysis module can also automatically analyze the medicinal ingredients and establish the property files of the medicinal materials by inputting the formula information of the Chinese patent medicine.

3. A classification system and method based on the efficacy of Chinese patent medicines according to claim 1, characterized in that: The compatibility relationship of the medicinal flavors includes but is not limited to one of mutually complementary, mutually usable, mutually fearful, and mutually antagonistic.

4. A classification system and method based on the efficacy of Chinese patent medicines according to claim 1, characterized in that: The classification module establishes a hierarchical structure of efficacy categories, allowing users to query and filter according to different classification criteria.

5. A classification method based on the efficacy of Chinese patent medicines, characterized by: The following steps are involved: S1: Collect the formula data of Chinese patent medicines and record the properties of each medicinal material, then conduct a compatibility analysis of the medicinal flavors to determine the ratio structure and conversion ratio of the medicinal flavors; S2: Apply the TCM theory of Tangye Jingfatu combined with the results of medicinal taste analysis to determine the efficacy category of Chinese patent medicines; S3: Formulate classification standards and classify Chinese patent medicines to establish a systematic classification system; S4: Visual display is achieved by drawing charts to help users intuitively view the information of medicinal materials and efficacy.

6. A classification system and method based on the efficacy of Chinese patent medicines according to claim 5, characterized in that: The properties of each medicinal material in step S1 include but are not limited to medicinal properties, medicinal taste, meridians, and functions in the prescription.

7. A classification system and method based on the efficacy of Chinese patent medicines according to claim 5, characterized in that: The visual display in step S4 includes the medicinal flavor compatibility structure of the medicinal materials, the dosage ratio, and the efficacy category of the Chinese patent medicine.

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