Preparation method of concentrated sow piglet health-care anti-diarrhea cream

By preparing concentrated female piglet health anti-diarrhea cream, high-pressure homogenized emulsification treatment of posophyllium liquid and other raw materials, the problems of insufficient nutrition, diarrhea and gastrointestinal dysfunction of female piglets were solved, and the effect of improving immunity and intestinal health and reducing drug stress was achieved.

CN119732441APending Publication Date: 2025-04-01JINAN TIANHUI FEED CO LTD
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Patent Information

Application Number
CN202411945156.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-27
Publication Date
2025-04-01

AI Technical Summary

Technical Problem

The existing technology is difficult to effectively solve problems such as insufficient nutritional intake, diarrhea and gastrointestinal dysfunction of female piglets, and common antibiotic treatment is prone to drug resistance and stress response.

Method used

The preparation method of concentrated female piglet health anti-diarrhea cream is adopted. The probiotic probiotic solution is prepared by fermenting and sterilizing enzymatic rice flour and whole milk powder, and mixed with other raw materials. After high-pressure homogenization, a solid-liquid suspension cream is prepared.

Benefits of technology

This cream can regulate the immunity and intestinal health of female piglets, reduce inflammation, improve gastrointestinal function, relieve constipation and diarrhea, improve the nutritional intake and reproductive performance of female piglets, and reduce the stress response caused by drug use.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to the technical field of preparation methods of sow piglet health products, and in particular to a preparation method of a concentrated sow piglet health anti-diarrhea cream, comprising the following steps: 1. preparing a postbiotic bacterial liquid; 2. preparing and grinding raw materials; 3. mixing the raw materials with the postbiotic bacterial liquid to obtain a mixture; and 4. slurry mixing and homogenizing. The invention has stable health and anti-diarrhea effects on piglets, can quickly supplement nutrition for thin piglets, and improve the uniformity of piglets; regulates the intestinal health of sows, relieves constipation, supplies high-efficiency nutrients, reduces the loss of sow body condition, and improves the reproductive performance of sows; meanwhile, the product has good appetitiveness, and its aqueous solution is sprinkled on sow piglet feed to induce feeding and enhance the appetite of sow piglets.
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Description

Technical Field

[0001] The invention relates to the technical field of preparation methods of sow piglet health products, and in particular to a preparation method of a concentrated sow piglet health anti-diarrhea cream. Background Art

[0002] In recent years, the number of piglets weaned in pig farms has not increased with the increase in litter size. The main reason is that the litter size has increased, sows have insufficient milk, and the nutritional needs of piglets have not been fully met. There are many thin and weak piglets, and the health of piglets is poor. However, there is a lack of relatively convenient and effective products on the market to quickly supplement nutrition and restore the body condition of young piglets. In addition, diarrhea is common in piglets, and sick and weak piglets are not rescued in time. The body condition and gastrointestinal damage are not repaired in time. Diarrhea in production is often treated with antibiotics and other drugs alone, which is too one-sided and easy to produce drug resistance, causing gastrointestinal flora disorders, decreased appetite, and the formation of stiff pigs. In addition, continuous injection and oral administration of antibiotics can easily cause greater stress to pigs.

[0003] Sows have the same problem during production. Long-term fixed-pen feeding and postpartum inflammation, stress and postpartum weakness can easily lead to decreased appetite, gastrointestinal dysfunction, constipation and other problems, resulting in insufficient nutrient intake for sows, leading to prenatal constipation, insufficient postpartum milk, excessive postpartum back tag loss and other problems, which reduce the weaning success rate and weaning weight of piglets, and also affect the reproductive performance of sows in the later period. Therefore, it is necessary to develop health care preparations specifically for sows and piglets to regulate gastrointestinal dysfunction and constipation in sows, diarrhea and poor health in piglets. Therefore, production urgently needs a preparation with good palatability (sows and piglets can actively eat) that can replace or reduce the greater stress caused by injections and lavages for piglets and sows. Summary of the invention

[0004] In order to solve the problems existing in the prior art, the present invention provides a concentrated sow piglet health anti-diarrhea cream, which is used to solve the immune function, intestinal health, anti-stress, diarrhea and other problems of sow piglets.

[0005] To solve the above problems, the technical solution of the present invention is as follows: a method for preparing a concentrated sow piglet health anti-diarrhea cream, comprising the following steps:

[0006] 1. Preparation of postbiotic bacterial liquid: add the mixture of enzymatic rice flour and whole milk powder to two fermentation tanks respectively, add water, stir and mix at a material-water ratio of 1:5-8, heat to 35-37°C and add bacteria to ferment respectively, heat to 50-100°C and sterilize after fermentation, mix the bacterial liquids in the two fermentation tanks evenly, and then perform homogenization and emulsification operation to make the probiotic cell body and the supernatant fully mixed and even without stratification, so as to obtain the postbiotic bacterial liquid of probiotics;

[0007] 2. Raw material preparation;

[0008] 3. mixing and grinding the raw material with a portion of the postbiotic bacterial liquid to obtain a mixture;

[0009] Fourth, slurry preparation and homogenization mixing are carried out. The postbiotic bacterial liquid is used as the base liquid, poured into a buffer tank, and the mixture obtained in step (iii) is added and stirred. The temperature is raised to 40-60 degrees to fully dissolve the above mixture and stir it evenly. The mixture is poured into a high-pressure homogenizer through a pipeline, and the homogenization and emulsification device is turned on with a pressure of 10-50 MPa to obtain a solid-liquid suspension cream with a uniform particle size of 100-200 nm, and finally canned into an extruded cream packaging bottle.

[0010] Furthermore, the raw materials in step (ii) include: 8%-16% whole milk powder, 3%-8% UPU structural fat, 6%-13% enzymatic rice flour protein, 1%-2% medium and short chain fatty acids, 0.1%-1% liquid vitamins and liquid organic trace elements, 0.5%-1% emulsifier, 0.1%-1% citric acid, and the rest is water. The dry powder raw materials are evenly mixed using a three-dimensional mixer for a mixing time of 3-10 minutes.

[0011] Furthermore, the raw materials in step (ii) also include 2%-10% of fish soluble bioactive small peptides.

[0012] Furthermore, the raw materials in step (ii) also include 0.5%-1% bee pollen.

[0013] Furthermore, the raw materials in step (ii) also include 0.6%-1.2% of antimicrobial peptides.

[0014] Furthermore, the raw materials in step (ii) also include 0.5%-1% chitosan oligosaccharide.

[0015] Furthermore, in the two fermentation tanks in step (i), the strain used in one of the fermentation tanks for fermenting the mixture of enzymatically hydrolyzed rice flour and whole milk powder is Lactobacillus plantarum.

[0016] Furthermore, in the two fermentation tanks in step (i), the strain used in the other fermentation tank for fermenting the mixture of enzymatically hydrolyzed rice flour and whole milk powder is Bacillus coagulans.

[0017] Further, in step (iii), the mixture is added with postbiotic bacterial liquid in a ratio of 1:6 between material and water, heated to 40-50° C. with stirring, poured into a large grinder for grinding and mixing, and the main component particles are ensured to be evenly ground and have a particle size of 100-200 nm.

[0018] Compared with the prior art, the present invention has the following beneficial effects: the postbiotic bacterial liquid contains a large amount of extracellular polysaccharides, short-chain fatty acids, enzymes and beneficial metabolites produced by fermentation, which can regulate the body's immunity, enhance the tight junction of intestinal epithelial cells, and improve the intestinal barrier function; reduce the production of inflammatory mediators and resist intestinal inflammation.

[0019] The invention has stable health care and anti-diarrhea effects on piglets, can quickly supplement nutrition for thin piglets, and improve the uniformity of piglets; regulate the intestinal health of sows, relieve constipation, supply high-efficiency nutrients, reduce the loss of sow body condition, and improve the reproductive performance of sows; at the same time, the product has good food attractant, and its aqueous solution can be sprinkled on the sow piglet feed to induce feeding and enhance the appetite of the sow piglets; it can reduce the injection of piglet health care injections and the health care operations of drug injection, so that pigs can actively eat and reduce the stress caused by injections and drug injections to pigs. DETAILED DESCRIPTION

[0020] Embodiment 1

[0021] A method for preparing a concentrated sow piglet health-care anti-diarrhea cream comprises the following steps:

[0022] 1. Preparation of postbiotic bacterial liquid: adding a mixture of enzymatic rice flour and whole milk powder to two fermentation tanks respectively, adding water, stirring and mixing at a material-water ratio of 1:5, heating to 35°C and adding strains for fermentation respectively, wherein one fermentation tank ferments the mixture of enzymatic rice flour and whole milk powder with strains of plant lactobacillus, and another fermentation tank ferments the mixture of enzymatic rice flour and whole milk powder with strains of coagulans, heating to 50°C for sterilization after the fermentation is completed, and after the sterilization is completed, the bacterial liquids in the two fermentation tanks are mixed evenly, and then homogenized and emulsified, so that the probiotic cell bodies and the supernatant are fully mixed and evenly without stratification, to obtain a postbiotic bacterial liquid of probiotics;

[0023] 2. Preparation of raw materials: The raw materials include: 8% whole milk powder, 3% UPU structural fat, 6% enzymatic rice flour protein, 1% medium and short chain fatty acids, 2% fish soluble bioactive peptides, 0.1% liquid vitamins and liquid organic trace elements, 0.5% bee pollen, 0.5% emulsifier, 0.5% chitosan oligosaccharide, 0.6% antibacterial peptide, 0.1% citric acid, and the rest is water. The raw materials are mixed evenly using a three-dimensional mixer for 3 minutes.

[0024] 3. The raw materials and the postbiotic bacterial liquid are mixed and ground to obtain a mixture; the mixture is added with the postbiotic bacterial liquid in a ratio of 1:4 between raw materials and water, heated to 40°C with stirring, poured into a large grinder for grinding and mixing, and the main component particles are ground evenly, with a particle size of 100-200nm.

[0025] Fourth, slurry preparation and homogenization mixing are carried out. The postbiotic bacterial liquid is used as the base liquid, poured into the buffer tank, and the mixture obtained in step (iii) is added and stirred. The temperature is raised to 40 degrees to allow the above mixture to be fully dissolved and stirred evenly. The mixture is poured into the high-pressure homogenizer through a pipeline, and the homogenization emulsification device is turned on with a pressure of 10Mpa to make a homogenous solid-liquid suspension cream with a uniform particle size distribution of 100-200nm, and finally canned into a squeeze cream packaging bottle.

[0026] Embodiment 2

[0027] A method for preparing a concentrated sow piglet health-care anti-diarrhea cream comprises the following steps:

[0028] 1. Preparation of postbiotic bacterial liquid: adding a mixture of enzymatic rice flour and whole milk powder to two fermentation tanks respectively, adding water, stirring and mixing at a material-water ratio of 1:6, heating to 36°C and adding strains for fermentation respectively, wherein one fermentation tank ferments the mixture of enzymatic rice flour and whole milk powder with strains of plant lactobacillus, and another fermentation tank ferments the mixture of enzymatic rice flour and whole milk powder with strains of coagulans, heating to 80°C for sterilization after the fermentation is completed, and after the sterilization is completed, the bacterial liquids in the two fermentation tanks are mixed evenly, and then homogenized and emulsified, so that the probiotic cell bodies and the supernatant are fully mixed and evenly without stratification, to obtain a postbiotic bacterial liquid of probiotics;

[0029] 2. Preparation of raw materials: The raw materials include: 12% whole milk powder, 5% UPU structural fat, 9% enzymatic rice flour protein, 1.5% medium and short chain fatty acids, 5% fish soluble bioactive peptides, 0.5% liquid vitamins and liquid organic trace elements, 0.7% bee pollen, 0.7% emulsifier, 0.7% chitosan oligosaccharide, 0.9% antibacterial peptide, 0.7% citric acid, and the rest is water. The raw materials are mixed evenly using a three-dimensional mixer for 5 minutes.

[0030] 3. The raw materials and the postbiotic bacterial liquid are mixed and ground to obtain a mixture; the mixture is added with the postbiotic bacterial liquid at a material-water ratio of 1:6, heated to 45°C with stirring, poured into a large grinder for grinding and mixing, and the main component particles are ground evenly, with a particle size of 100-200nm.

[0031] Fourth, slurry preparation and homogenization mixing are carried out. The postbiotic bacterial liquid is used as the base liquid, poured into the buffer tank, and the mixture obtained in step (iii) is added and stirred. The temperature is raised to 50 degrees to allow the above mixture to be fully dissolved and stirred evenly. The mixture is poured into the high-pressure homogenizer through a pipeline, and the homogenization emulsification device is turned on at a pressure of 30 MPa to make a homogeneous solid-liquid suspension cream with a uniform particle size distribution of 100-200 nm, and finally canned into a squeeze cream packaging bottle.

[0032] Embodiment 3

[0033] A method for preparing a concentrated sow piglet health-care anti-diarrhea cream comprises the following steps:

[0034] 1. Preparation of postbiotic bacterial liquid: adding a mixture of enzymatic rice flour and whole milk powder to two fermentation tanks respectively, adding water, stirring and mixing at a material-water ratio of 1:8, heating to 37°C and adding strains for fermentation respectively, wherein one fermentation tank ferments the mixture of enzymatic rice flour and whole milk powder with strains of plant lactobacillus, and another fermentation tank ferments the mixture of enzymatic rice flour and whole milk powder with strains of coagulans, heating to 100°C for sterilization after fermentation, and after sterilization, mixing the bacterial liquids in the two fermentation tanks evenly, and then performing a homogenization and emulsification operation, so that the probiotic cell bodies and the supernatant are fully mixed and evenly without stratification, to obtain a postbiotic bacterial liquid of probiotics;

[0035] 2. Preparation of raw materials: The raw materials include: 16% whole milk powder, 8% UPU structural fat, 13% enzymatic rice flour protein, 2% medium and short chain fatty acids, 10% fish soluble bioactive peptides, 1% liquid vitamins and liquid organic trace elements, 1% bee pollen, 1% emulsifier, 1% chitosan oligosaccharide, 1.2% antibacterial peptides, 1% citric acid, and the rest is water. The raw materials are mixed evenly using a three-dimensional mixer for 10 minutes.

[0036] 3. The raw materials and the postbiotic bacterial liquid are mixed and ground to obtain a mixture; the mixture is added with the postbiotic bacterial liquid at a material-water ratio of 1:8, heated to 50°C with stirring, poured into a large grinder for grinding and mixing, and the main component particles are ground evenly, with a particle size of 100-200nm.

[0037] Fourth, slurry preparation and homogenization mixing are carried out. The postbiotic bacterial liquid is used as the base liquid, poured into the buffer tank, and the mixture obtained in step (iii) is added and stirred. The temperature is raised to 60 degrees to allow the above mixture to be fully dissolved and stirred evenly. The mixture is poured into the high-pressure homogenizer through a pipeline, and the homogenization emulsification device is turned on at a pressure of 50 MPa to make a homogenous particle size distribution of 100-200 nm solid-liquid suspension cream, which is finally canned into a squeeze cream packaging bottle.

[0038] The comparison example is as follows

[0039] Experiment on feeding sows with health cream:

[0040] Twenty constipated sows were selected and randomly divided into a control group and an experimental group. A certain amount of health cream was added to the feed trough of the experimental group during each feeding. The feces of the sows in the experimental and control groups were observed after 5 days.

[0041] Grouping Experimental group (10 sows) Control group (10 sows) Sow supplementary feeding health cream Constipation Good for loading, soft stool No change, hard stool Feeding situation Increased food intake and appetite Loss of appetite

[0042] The above observation experiments also show that the health cream has a positive effect on sow constipation and appetite recovery.

[0043] Experiment on feeding piglets with health cream:

[0044] Twenty Large White sows in the fifth parity of lactation were selected, and the litter size was adjusted to 13 piglets per litter. They were randomly divided into an experimental group and a control group. The experimental group was fed or gavaged with piglet health cream, and the control group was fed a basic diet. The piglets' feed intake, weaning weight and mortality were recorded every day.

[0045] Data on changes in feed intake after piglets were fed with health cream:

[0046] Grouping Experimental Group Control group Piglets actively eat health cream Initial number of heads 130 130 End number 126 119 Average feed intake per litter (g) 719.8 598.8

[0047] Experimental results: The feed intake of the experimental group fed with health cream was higher than that of the control group, with an average increase of 121g per litter.

[0048] Growth performance data of piglets after feeding health cream:

[0049]

[0050] The average litter weight at the end of the test group was 4.15kg higher than that of the control group, and the average litter weight gain was 2.93kg higher than that of the control group; 7 fewer pigs died than in the control group, and most of the dead pigs were weak piglets or piglets with diarrhea, indicating that the present invention has a high value in improving weaning weight and piglet survival rate.

[0051] The sow and piglet cream of the present application utilizes the principle of disease-resistant nutrition, adopts high-quality raw materials, functional additives and antibiotic-free bactericides, and uses liquid vitamins and trace elements, fish-soluble bioactive peptides, medium- and short-chain fatty acids, a variety of probiotics and postbiotics, and bee pollen to improve the immunity and disease resistance of sows and piglets, enhance the body's resistance to non-specific diseases, improve gastrointestinal function, and relieve constipation and diarrhea.

[0052] Whole milk powder, UPU structural fat, enzymatic rice flour protein and fish soluble bioactive peptides are used to supplement high-quality protein peptides and breast milk structural fat. The rice flavor, milk flavor and fresh flavor enhance the product's appetizingness, quickly replenish nutrition, restore the sow's body condition, and provide energy for thin piglets.

[0053] A variety of probiotics, postbiotics, bee pollen, chitosan oligosaccharides and antimicrobial peptides are used to control piglet diarrhea, regulate gastrointestinal function, and solve the problems of sow constipation and piglet diarrhea.

[0054] The palatability of the medicine is increased, and it has sour, sweet, fresh and milky flavors. Compared with solid preparations, it is easier for the flavor and better taste to spread in the sow piglet's mouth, allowing the piglets to actively swallow and eat, thereby increasing the sow's feed intake.

[0055] It contains UPU structural fat, medium and short-chain fatty acids and other nutrients needed by piglets. It can relieve piglet diarrhea while replenishing energy for thin piglets, replenishing the loss of nutrients caused by diarrhea and dehydration, quickly functioning and improving the uniformity of piglets.

[0056] It contains a variety of beneficial sow nutrients such as probiotics, postbiotics, chitosan oligosaccharides, bee pollen and fish lava peptides, which can improve gastrointestinal function and increase sow appetite.

[0057] The breast milk paste of the present application avoids the waste of liquid products flowing out of the piglets' mouths when administering the products, and also avoids the occurrence of solid products that are difficult to swallow.

[0058] The sow piglet cream of the present application is very easy to dissolve in water, which is convenient for the operation of dissolving water to supplement feeding for sow piglets. Due to the excellent appetitiveness of the product, its aqueous solution can be sprinkled on the sow piglet feed to induce feeding and enhance the appetite of the sow piglets.

[0059] The above specific implementation methods are only used to illustrate the technical solution of the present invention rather than to limit it. Although the present invention has been described in detail with reference to examples, a person skilled in the art should understand that the technical solution of the present invention can be modified or replaced by equivalents without departing from the scope of the technical solution of the present invention, which should be included in the scope of the claims of the present invention.

Claims

1. A method for preparing a concentrated sow piglet health anti-diarrhea cream, characterized in that: The following steps are included:

1. Preparation of postbiotic bacterial liquid: add the mixture of enzymatic rice flour and whole milk powder to two fermentation tanks respectively, add water, stir and mix at a material-water ratio of 1:5-8, heat to 35-37°C and add bacteria to ferment respectively, heat to 50-100°C and sterilize after fermentation, mix the bacterial liquids in the two fermentation tanks evenly, and then perform homogenization and emulsification operation to make the probiotic cell body and the supernatant fully mixed and even without stratification, so as to obtain the postbiotic bacterial liquid of probiotics; 2. Raw material preparation; 3. mixing and grinding the raw materials and the postbiotic bacterial liquid to obtain a mixture; Fourth, slurry preparation and homogenization mixing are carried out. The postbiotic bacterial liquid is used as the base liquid, poured into a buffer tank, and the mixture obtained in step (iii) is added and stirred. The temperature is raised to 40-60 degrees to fully dissolve the above mixture and stir it evenly. The mixture is poured into a high-pressure homogenizer through a pipeline, and the homogenization and emulsification device is turned on with a pressure of 10-50 MPa to obtain a solid-liquid suspension cream with a uniform particle size of 100-200 nm, and finally canned into an extruded cream packaging bottle.

2. The preparation method according to claim 1, characterized in that: The raw materials in step (ii) include: 8%-16% whole milk powder, 3%-8% UPU structural fat, 6%-13% enzymatic rice flour protein, 1%-2% medium- and short-chain fatty acids, 0.1%-1% liquid vitamins and liquid organic trace elements, 0.5%-1% emulsifier, 0.1%-1% citric acid, and the rest is water. The dry powder raw materials are evenly mixed by a three-dimensional mixer for 3-10 minutes.

3. The preparation method according to claim 2, characterized in that: The raw materials in step (ii) also include 2%-10% of fish soluble bioactive small peptides.

4. The preparation method according to claim 3, characterized in that: The raw materials in step (ii) also include 0.5%-1% bee pollen.

5. The preparation method according to claim 4, characterized in that: The raw materials in step (ii) also include 0.6%-1.2% of antimicrobial peptides.

6. The preparation method according to claim 5, characterized in that: The raw materials in step (ii) also include 0.5%-1% chitosan oligosaccharide.

7. The preparation method according to claim 1, characterized in that: In the two fermentation tanks in step (i), one of the fermentation tanks uses Lactobacillus plantarum to ferment the mixture of enzymatically hydrolyzed rice flour and whole milk powder.

8. The preparation method according to claim 1, characterized in that: In the two fermentation tanks in step (i), the strain used in the other fermentation tank for fermenting the mixture of enzymatically hydrolyzed rice flour and whole milk powder is Bacillus coagulans.

9. The preparation method according to claim 1, characterized in that: In step (iii), the mixture is added with postbiotic bacterial liquid in a ratio of 1:4-8 between material and water, heated to 40-50°C with stirring, poured into a large grinder for grinding and mixing, and the main component particles are ground evenly to a particle size of 100-200 nm.