3D printing device for biomimetic skin grafting

Abstract

The present invention provides a 3D printing device for biological simulation skin grafting, which relates to the technical field of 3D printing, and comprises a printing box, wherein a printing nozzle is installed on the inner wall of the top of the printing box through a three-axis moving device, an ink cartridge is installed on the outer end of the top of the printing box, a placement table is arranged at the bottom of the interior of the printing box, and a printing box is placed on the placement table, a delivery inlet is arranged on one side of the printing box, and the delivery inlet is fixedly connected to a storage box, a delivery outlet is arranged on the other side of the printing box, and the delivery outlet is connected to a collection box, and multiple layers of collection plates are fixed at equal intervals inside the collection box. Compared with the prior art, the collection box is installed at the delivery outlet position of the printing box through a connecting component, and after printing in the printing box is completed, the delivery component pushes it into the limit frame, and after each layer of collection plates is collected, the collection box can be automatically lifted to collect the next group, thereby improving printing and collection efficiency and reducing the intensity of manual work.

Description

Technical Field

[0001] The present invention relates to the technical field of 3D printing, in particular to a 3D printing device for biological simulation skin grafting. Background Art

[0002] 3D printing can print functional human-like skin, that is, it has the functions of human skin and can be used for skin grafting in medicine. The raw materials used include "bio-ink" composed of plasma, protein and skin cells. For skin grafting in medicine, the patient's own skin cells are needed, and then the researchers culture them in the laboratory for about two weeks, and then complete bio-printing in one or two days. Specifically, the preparation of bio-ink: bio-ink is usually composed of hydrogel, fibrinogen, induction factor and stem cells. Stem cells are extracted from the wounded and can be used for printing after 1-2 days of in vitro expansion. 3D printing process: Using an extrusion-type biological 3D printer, the three-dimensional structure of the skin is constructed by stacking layers through precise control of bio-ink. Under the action of induction factors, stem cells differentiate into various mature skin cells. Cell culture: After printing, the cells continue to be cultured in a specific environment, and finally form functional artificial skin. Transplantation: The printed skin can be directly attached to the wound surface without suturing. It will merge with the original skin within 3-7 days to form a complete skin coverage.

[0003] After the 3D printed skin is completed, it needs to be stored and cultured in a specific environment and cannot be used directly. With existing 3D printing technology, manual operation is usually required to take out and put in the printed objects. For patients who need a large amount of skin grafts, the efficiency is low and efficient skin graft printing and delivery cannot be achieved. Summary of the invention

[0004] In view of the shortcomings of the prior art, the purpose of the present invention is to provide a 3D printing device for bio-simulation skin grafting to solve the problems raised in the above-mentioned background technology. The present invention has a novel structure. The collection box is installed at the delivery outlet of the printing box through a connecting component. After printing in the printing box is completed, the delivery component pushes it into the limit frame. After each layer of collection plate is collected, the collection box can be automatically lifted for the next group of collection, thereby improving the printing and collection efficiency and reducing the intensity of manual work.

[0005] In order to achieve the above-mentioned purpose, the present invention is realized through the following technical scheme: a 3D printing device for biological simulation skin grafting, comprising a printing box, a printing nozzle is installed on the inner wall of the top of the printing box through a three-axis moving device, an ink cartridge is installed on the outer end of the top of the printing box, a placement table is arranged at the bottom of the inside of the printing box, and a printing box is placed on the placement table, a delivery inlet is arranged on one side of the printing box, and the delivery inlet is fixedly connected to a storage box, a delivery outlet is arranged on the other side of the printing box, and the delivery outlet is connected to a collection box, multiple layers of collection plates are equidistantly fixed inside the collection box, and two sets of limit frames are fixed on the surface of each layer of the collection plate, so that A delivery component is provided between the placement table and the collection plate, and the delivery component includes a limit plate. The placement table is located on both sides of the print box and fixed with limit plates. The limit plate is fixed with an inclined plate at one end of the limit plate facing the delivery outlet, and the inclined plate corresponds to the outermost side of the two limit frames. A guide plate is rotatably installed between the two groups of the inclined plates through an axle rod and a torsion spring. A connecting component is provided on the outer side of the print box and the collection box, and the connecting component includes an insertion frame. Insertion frames are fixed on both sides of the top of the collection box, and insertion plates are provided at the position of the print box corresponding to the insertion frames, and the insertion plates are slidably inserted in the insertion frames. A baffle is fixed on the top surface of the print box at the outer end of the delivery outlet.

[0006] Furthermore, spare printing boxes are stacked inside the storage box, and a first electric push rod is fixed to the rear end of the storage box, and the first electric push rod pushes the printing box onto the placement table.

[0007] Furthermore, a bottom plate is fixed to the bottom of the collection box, pulleys are installed at the four corners of the bottom of the bottom plate, spring telescopic rods are fixed to the tops of both sides of the bottom plate, and the extended ends of the spring telescopic rods are fixedly connected to the collection box.

[0008] Furthermore, a pressing plate is slidably connected inside the limiting frame, and a first spring is fixed equidistantly between the pressing plate and the innermost side of the limiting frame.

[0009] Furthermore, the connection assembly also includes a second electric push rod, and the second electric push rod is fixed on the outer walls of the printing box located on both sides of the collection box, and the extended end of the second electric push rod is fixedly connected to the plug plate.

[0010] Furthermore, a sealing plate is slidably installed at the front end of the collection box, and studs are threadedly inserted on both sides of the bottom of the sealing plate of the collection box. Screw hole plates are fixed at positions corresponding to the studs on both sides of the bottom of the collection box, and the studs are threadedly inserted inside the screw hole plates. A plug is fixed at the other end of the stud, and sockets are opened at positions corresponding to the two plugs at the bottom of the printing box, and the plugs are slidably inserted inside the sockets.

[0011] Furthermore, the delivery component also includes a movable groove, movable grooves are opened on both sides of the limit frame, and outer plates are fixed on both ends of the extrusion plate passing through the movable grooves. A transmission belt is installed on the top of the side of one group of limit frames on the collection plate, and the extrusion plate is fixedly connected to the lower end belt of the transmission belt.

[0012] Furthermore, a toothed plate is rotatably mounted on the upper end of the transmission belt, a gear is sleeved on the surface of the shaft at the bottom of the guide plate, and the toothed plate is meshingly connected with the gear.

[0013] Furthermore, a rangefinder is fixed to the bottom of the guide plate of the printing box, and the rangefinder corresponds to the outer plates extending from the sides of the two groups of limit frames.

[0014] Furthermore, a screw is rotatably installed inside the limit plate through a small motor and a bearing, and a moving block is threadedly sleeved on the surface of the screw, and an electromagnetic clamp is installed on the surface of the moving block.

[0015] Beneficial effects of the present invention:

[0016] 1. The present invention uses a distance meter to measure the distance between the outer plates of the two side edges of the limit frames on the same collection plate. When the two distances are at the predetermined maximum distance, it means that each limit frame is full of print cartridges. At this time, an electrical signal is transmitted to the second electric push rod, and the second electric push rod moves the collection box upward, continues to move the new collection plate to the delivery component, and at the same time, the first electric push rod pushes the new print cartridge inside the storage box onto the placement table.

[0017] 2. The present invention moves the transmission belt, and when one end of the toothed plate moves forward and approaches the gear position, it contacts and meshes with the gear at the bottom of the guide plate, thereby driving the guide plate to rotate. When the toothed plate moves to the front end of the limit frame, it indicates that the inside of the limit frame is fully loaded. At this time, the guide plate also rotates to the lower end, and the print boxes that continue to be sent out will be transported to the inside of the limit frame at the upper end, thereby completing the alternating switching of the two groups of limit frames in the same collection plate to collect the print boxes and neatly store the print boxes.

[0018] 3. When the collection box is connected to the printing box, the present invention first separates the stud of the sealing plate from the screw hole plate, and inserts the plug at the other end of the stud into the jack at the bottom of the printing box, and then plugs the plug plate into the plug frame. After detecting that each layer of collection plates inside the collection box has been collected, the second electric push rod drives the collection box to move upward, and replaces the new collection plate to the position of the delivery outlet. The collection box can be stored as a box through the locking connection of the sealing plate and the stud, and the installation of the spring telescopic rod and the bottom plate, which is convenient for transportation and storage.

[0019] 4. The present invention uses the elastic force of the second spring and the third spring to restore the limit wrapping of the detection device box, so that it has stability during the detection process. Different detection instruments or tools are configured inside different box doors on the detection box, which can be selectively used as needed, saving time in searching for detection tools. When not in use, the cushion, the mounting plate and the annular belt can be stored inside the storage frame by moving the first rack. The top rack acts as a handle, and the device can be lifted and moved.

[0020] 5. Compared with the prior art, the present invention installs the collection box at the delivery outlet of the print box through a connecting component. After printing in the print box is completed, the delivery component pushes it into the limit frame. After each layer of collection plate is collected, the collection box can be automatically lifted for the next group of collection, thereby improving printing and collection efficiency and reducing the intensity of manual work. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 This is a schematic diagram of the overall front structure of the 3D printing device for bio-simulation skin grafting of the present invention;

[0022] Figure 2 This is a schematic diagram of the overall back structure of the 3D printing device for bio-simulation skin grafting of the present invention;

[0023] Figure 3 This is a schematic diagram of the internal structure of a printing box of a 3D printing device for biological simulation skin grafting of the present invention;

[0024] Figure 4 This is a schematic diagram of the structure of the connection components of the 3D printing device for bio-simulation skin grafting of the present invention;

[0025] Figure 5 This is a schematic diagram of the separation of the printing box and the collecting box of the 3D printing device for bio-simulation skin grafting of the present invention;

[0026] Figure 6 This is a schematic diagram of the top structure of the placement table of the 3D printing device for biological simulation skin grafting of the present invention;

[0027] Figure 7 A top view of a delivery component of a 3D printing device for bio-simulation skin grafting according to the present invention;

[0028] Figure 8 This is a schematic diagram of the side structure of the limit frame of the 3D printing device for bio-simulation skin grafting of the present invention.

[0029] In the figure: 1. print box; 11. ink cartridge; 12. delivery port; 13. storage box; 14. first electric push rod; 15. placement table; 16. delivery port; 17. print nozzle; 2. collection box; 21. bottom plate; 22. spring telescopic rod; 23. pulley; 24. collection plate; 25. limit frame; 26. first spring; 27. extrusion plate; 3. connecting assembly; 31. second electric push rod; 32. plug frame; 33. plug plate; 34. jack; 35. stud; 36. plug; 37. screw hole plate; 4. delivery assembly; 41. limit plate; 42. screw rod; 43. moving block; 44. electromagnetic clamp; 45. print box; 46. inclined plate; 47. guide plate; 48. tooth plate; 49. moving groove; 410. transmission belt; 411. outer plate; 412. rangefinder. DETAILED DESCRIPTION

[0030] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further explained below in conjunction with specific implementation methods.

[0031] See also Figures 1 to 8The present invention provides a technical solution: a 3D printing device for biological simulation skin grafting, comprising a printing box 1, a printing nozzle 17 is installed on the top inner wall of the printing box 1 through a three-axis moving device, an ink cartridge 11 is installed on the top outer end of the printing box 1, a placing table 15 is arranged at the bottom of the printing box 1, and a printing box 45 is placed on the placing table 15, a feeding port 12 is arranged on one side of the printing box 1, and the feeding port 12 is fixedly connected to a storage box 13, a delivery outlet 16 is arranged on the other side of the printing box 1, and the delivery outlet 16 is connected to a collection box 2, a plurality of collecting plates 24 are fixed at equal intervals inside the collection box 2, two groups of limit frames 25 are fixed on the surface of each layer of the collecting plate 24, a delivery component 4 is arranged between the placing table 15 and the collecting plate 24, and the delivery component 4 includes a limit plate 41, the placing table 15 is located on both sides of the printing box 45, and the limit plates 41 are fixed to the end of the limit plate 41 facing the delivery outlet 16, and the inclined plate 46 is fixed 6 corresponds to the outermost side of the two limit frames 25, and a guide plate 47 is rotatably installed between the two groups of the inclined plates 46 through a shaft and a torsion spring. A connecting component 3 is provided on the outer side of the printing box 1 and the collecting box 2, and the connecting component 3 includes an insert frame 32. Insert frames 32 are fixed on both sides of the top of the collecting box 2. Insert plates 33 are provided at the position of the printing box 1 corresponding to the insert frame 32, and the insert plates 33 are slidably inserted in the insert frame 32. A baffle is fixed on the top surface of the outer end of the delivery outlet 16 of the printing box 1. The technology used by the print nozzle 17 and the ink cartridge 11 in this scheme is the same as the existing technology for 3D printing artificial skin. When using the device, the collecting box 2 is installed on one side of the delivery outlet 16 of the printing box 1 through the connecting component 3, and the print box 45 is placed on the placement table 15. Printing is performed by the print nozzle 17. After printing is completed, it is sent into the collection box 2 through the delivery component 4, and is evenly and equidistantly stacked in the collection box 2, which is convenient for uniformly storing and arranging the printed artificial skin.

[0032] In this embodiment, spare print cartridges 45 are stacked inside the storage box 13, and a first electric push rod 14 is fixed to the rear end of the storage box 13. The first electric push rod 14 pushes the print cartridges 45 onto the placement table 15. This part of the structure is a common loading structure, and the print cartridges 45 can be pre-stacked inside the storage box 13 and pushed one by one onto the placement table 15 by the first electric push rod 14.

[0033] In this embodiment, a bottom plate 21 is fixed to the bottom of the collection box 2, pulleys 23 are installed at the four corners of the bottom of the bottom plate 21, spring telescopic rods 22 are fixed to the tops of both sides of the bottom plate 21, and the extended ends of the spring telescopic rods 22 are fixedly connected to the collection box 2, the connecting assembly 3 also includes a second electric push rod 31, the second electric push rod 31 is fixed to the outer walls of the printing box 1 on both sides of the collection box 2, and the extended ends of the second electric push rod 31 are fixedly connected to the plug plate 33, a sealing plate is slidably installed at the front end of the collection box 2, studs 35 are threadedly inserted on both sides of the bottom of the sealing plate of the collection box 2, screw hole plates 37 are fixed at the positions corresponding to the studs 35 on both sides of the bottom of the collection box 2, the studs 35 are threadedly inserted inside the screw hole plates 37, and the studs 35 are threadedly inserted inside the screw hole plates 37. A plug 36 is fixed to the other end, and a socket 34 is provided at the position corresponding to the two plugs 36 at the bottom of the printing box 1, and the plug 36 is slidably inserted into the socket 34. When the collection box 2 is connected to the printing box 1, the stud 35 of the sealing plate is first separated from the screw hole plate 37, and the plug 36 at the other end of the stud 35 is inserted into the socket 34 at the bottom of the printing box 1, and then the plug plate 33 is plugged into the plug frame 32. After detecting that the collection of each layer of collection plates 24 inside the collection box 2 is completed, the second electric push rod 31 drives the collection box 2 to move upward, and replaces the new collection plate 24 to the position of the delivery outlet 16. The collection box 2 can be stored as a box through the locking connection between the sealing plate and the stud 35, and the installation of the spring telescopic rod 22 and the bottom plate 21, which is convenient for transportation and storage.

[0034] In this embodiment, the limit frame 25 is internally slidably connected with an extrusion plate 27, and a first spring 26 is equidistantly fixed between the extrusion plate 27 and the innermost side of the limit frame 25. The delivery component 4 also includes a moving groove 49. The two sides of the limit frame 25 are provided with moving grooves 49. The two ends of the extrusion plate 27 pass through the moving grooves 49 and are fixed with outer plates 411. A transmission belt 410 is installed on the top of the side of one group of limit frames 25 on the collecting plate 24. The extrusion plate 27 is fixedly connected to the lower end belt of the transmission belt 410. The upper end belt of the transmission belt 410 is rotatably installed with a toothed plate 48. The shaft rod surface at the bottom of the guide plate 47 is sleeved The gear plate 48 is connected to the gear, and the gear plate 48 is meshed with the gear. The limit plate 41 is internally installed with a screw rod 42 through a small motor and a bearing, and a moving block 43 is threadedly sleeved on the surface of the screw rod 42. An electromagnetic clamping plate 44 is installed on the surface of the moving block 43. The working principle of the electromagnetic clamping plate 44 on the moving block 43 is to have a certain clamping effect on the print box 45 and can be retracted. After the skin grafting printing in the print box 45 is completed, the movable frame slides along the inside of the limit plate 41 through the rotation of the screw rod 42, and the print box 45 is sent to the position of the inclined plate 46 through the electromagnetic clamping plate 44. In this part, the initial position of the guide plate 47 is based on Figure 7The guide plate 47 also rotates to the lower end, and the print cartridge 45 that continues to be sent out will be transported to the upper end of the limit frame 25, so as to complete the alternating switching of the two groups of limit frames 25 in the same collecting plate 24 to collect the print cartridges 45 and neatly store the print cartridges 45. A rubber block, not shown in the figure, is provided at the front end of the limit frame 25, which serves as a limit structure to prevent the sent print cartridges 45 from running out.

[0035] In this embodiment, a rangefinder 412 is fixed to the bottom of the guide plate 47 of the print box 1. The rangefinder 412 corresponds to the outer plates 411 extending from the sides of the two sets of limit frames 25. The rangefinder 412 is used to measure the distance between the outer plates 411 on the sides of the two limit frames 25 on the same collecting plate 24. When both distances are at the predetermined farthest distance, it means that each limit frame 25 is full of print boxes 45. At this time, an electrical signal is transmitted to the second electric push rod 31, and the second electric push rod 31 moves the collecting box 2 upward, and continues to send out the new collecting plate 24 to the corresponding component 4. At the same time, the first electric push rod 14 pushes the new print box 45 in the storage box 13 onto the placement table 15.

[0036] When using the device, the collection box 2 is installed on the side of the delivery outlet 16 of the print box 1 through the connecting assembly 3, and the print box 45 is placed on the placement table 15, and printing is performed through the print nozzle 17. After the skin graft printing in the print box 45 is completed, the movable frame slides along the inner side of the limit plate 41 through the rotation of the screw rod 42, and the print box 45 is sent to the position of the inclined plate 46 through the electromagnetic clamping plate 44. In this part, the initial position of the guide plate 47 is based on Figure 7The guide plate 47 also rotates to the lower end, and the print cartridge 45 that continues to be sent out will be transported to the upper end of the limit frame 25, thereby completing the alternating switching of the two groups of limit frames 25 in the same collecting plate 24 to collect the print cartridges 45 and neatly store the print cartridges 45. The rangefinder 412 is used to measure the distance between the outer plates 411 on the sides of the two limit frames 25 on the same collecting plate 24. When the two distances are both at When it reaches the predetermined farthest point, it indicates that each limit frame 25 is already filled with print cartridges 45. At this time, an electrical signal is transmitted to the second electric push rod 31, which moves the collection box 2 upwards and continues to move the new collection plate 24 to the corresponding delivery assembly 4. At the same time, the first electric push rod 14 pushes the new print cartridge 45 inside the storage box 13 onto the placement table 15. When the collection box 2 is connected to the print box 1, first separate the stud 35 of the sealing plate from the screw hole plate 37, and insert the plug 36 at the other end of the stud 35 into the socket 34 at the bottom of the print box 1, and then connect the plug plate 33 with the plug frame 32. After detecting that the collection of each layer of collection plates 24 inside the collection box 2 is completed, the second electric push rod 31 drives the collection box 2 to move upwards and replaces the new collection plate 24 to the position of the delivery outlet 16. The collection box 2 can be stored as a box through the locking connection between the sealing plate and the stud 35, and the installation of the spring telescopic rod 22 and the bottom plate 21, which is convenient for transportation and storage.

[0037] The basic principles and main features of the present invention and the advantages of the present invention are shown and described above. For those skilled in the art, it is obvious that the present invention is not limited to the details of the above exemplary embodiments, and the present invention can be implemented in other specific forms without departing from the spirit or basic characteristics of the present invention.

[0038] In addition, it should be understood that although the present specification is described according to implementation modes, not every implementation mode contains only one independent technical solution. This description of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment may also be appropriately combined to form other implementation modes that can be understood by those skilled in the art.

Claims

1. A 3D printing device for bio-simulation skin grafting, comprising a printing box (1), characterized in that: A printing nozzle (17) is installed on the top inner wall of the printing box (1) through a three-axis moving device, an ink cartridge (11) is installed on the top outer end of the printing box (1), a placement table (15) is arranged at the bottom of the interior of the printing box (1), and a printing cartridge (45) is placed on the placement table (15), a feeding port (12) is arranged on one side of the printing box (1), and the feeding port (12) is fixedly connected to a storage box (13), a delivery port (16) is arranged on the other side of the printing box (1), and the delivery port (16) is connected to a collection box (2), multiple layers of collection plates (24) are fixed at equal distances inside the collection box (2), and two groups of limit frames (25) are fixed on the surface of each layer of the collection plate (24), and a delivery component (4) is arranged between the placement table (15) and the collection plate (24), and the delivery component (4) includes a limit The placing platform (15) is provided with a limit plate (41) fixed on both sides of the printing box (45), an inclined plate (46) is fixed on one end of the limit plate (41) facing the delivery outlet (16), and the inclined plate (46) corresponds to the outermost sides of the two limit frames (25), and a guide plate (47) is rotatably installed between the two groups of the inclined plates (46) through a shaft and a torsion spring, a connecting component (3) is provided on the outer sides of the printing box (1) and the collecting box (2), and the connecting component (3) includes an insert frame (32), and the insert frames (32) are fixed on both sides of the top of the collecting box (2), and the printing box (1) is provided with an insert plate (33) at a position corresponding to the insert frame (32), and the insert plate (33) is slidably inserted in the insert frame (32), and a baffle is fixed on the top surface of the printing box (1) at the outer end of the delivery outlet (16).

2. The 3D printing device for bio-simulation skin grafting according to claim 1, characterized in that: Spare printing boxes (45) are stacked inside the storage box (13), and a first electric push rod (14) is fixed at the rear end of the storage box (13), and the first electric push rod (14) pushes the printing box (45) onto the placement table (15).

3. The 3D printing device for bio-simulation skin grafting according to claim 1, characterized in that: A bottom plate (21) is fixed at the bottom of the collection box (2), pulleys (23) are installed at the four corners of the bottom of the bottom plate (21), spring telescopic rods (22) are fixed at the tops of both sides of the bottom plate (21), and the extended ends of the spring telescopic rods (22) are fixedly connected to the collection box (2).

4. The 3D printing device for bio-simulation skin grafting according to claim 3, characterized in that: The limiting frame (25) is internally slidably connected with a pressing plate (27), and a first spring (26) is fixed equidistantly between the pressing plate (27) and the innermost side of the limiting frame (25).

5. The 3D printing device for bio-simulation skin grafting according to claim 3, characterized in that: The connecting assembly (3) further comprises a second electric push rod (31), the second electric push rod (31) being fixed on the outer walls of the printing box (1) on both sides of the collecting box (2), and the extended end of the second electric push rod (31) is fixedly connected to the plug plate (33).

6. The 3D printing device for bio-simulation skin grafting according to claim 5, characterized in that: A sealing plate is slidably mounted at the front end of the collection box (2), studs (35) are threadedly inserted at both sides of the bottom of the sealing plate of the collection box (2), screw hole plates (37) are fixed at positions corresponding to the studs (35) at the bottom of both sides of the collection box (2), the studs (35) are threadedly inserted inside the screw hole plates (37), and a plug (36) is fixed at the other end of the stud (35), and a plug hole (34) is opened at the position of the bottom of the printing box (1) corresponding to the two plugs (36), and the plug (36) is slidably inserted inside the plug hole (34).

7. The 3D printing device for bio-simulation skin grafting according to claim 4, characterized in that: The delivery assembly (4) further comprises a movable groove (49), the movable grooves (49) are provided on both sides of the limit frame (25), both ends of the extrusion plate (27) pass through the movable grooves (49) and are fixed with outer plates (411), a transmission belt (410) is installed at the top of the side of one group of limit frames (25) on the collection plate (24), and the extrusion plate (27) is fixedly connected to the lower end belt of the transmission belt (410).

8. The 3D printing device for bio-simulation skin grafting according to claim 7, characterized in that: The upper end of the transmission belt (410) is rotatably mounted with a toothed plate (48), the shaft surface at the bottom of the guide plate (47) is sleeved with a gear, and the toothed plate (48) is meshingly connected with the gear.

9. The 3D printing device for bio-simulation skin grafting according to claim 8, characterized in that: The printing box (1) is fixed with a distance meter (412) at the bottom of the guide plate (47), and the distance meter (412) corresponds to the outer plates (411) extending from the sides of the two sets of limit frames (25).

10. The 3D printing device for bio-simulation skin grafting according to claim 9, characterized in that: A screw rod (42) is rotatably mounted inside the limit plate (41) via a small motor and a bearing, and a moving block (43) is threadedly sleeved on the surface of the screw rod (42), and an electromagnetic clamping plate (44) is mounted on the surface of the moving block (43).

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