Mixed bacterial agent for reducing antibiotic resistance genes and application thereof

The synergistic effect of a mixed microbial agent, Neobacillus sedimentimangrovi J35 and Brevundimonas terrae KanS2, secretes H2O2 to degrade resistance genes in compost, solving the problems of low removal efficiency and high cost in existing technologies, and achieving efficient and safe reduction of resistance genes.

CN119752682BActive Publication Date: 2026-03-27FUJIAN AGRI & FORESTRY UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-12-02
Publication Date
2026-03-27

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Abstract

The application belongs to the field of microbial application, and discloses a mixed bacterial agent for reducing antibiotic resistance genes and application of the mixed bacterial agent. The mixed bacterial agent comprises Neobacillus sedimentimangrovi J35 and Brevundimonas terrae KanS2, and the preservation numbers are CCTCC NO: M 20241436 and CCTCC NO: M 20241435 respectively. The two bacteria in the mixed bacterial agent of the application are symbiotic, secrete H2O2, and utilize the strong oxidizing property of the secreted H2O2 to degrade ARGs in compost, so that the reduction efficiency of ARGs reaches 94.5% at most, ARGs in compost products can be effectively controlled, the safety and environmental protection of compost treatment are improved, and the application has wide application prospect.
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Citation Information

Patent Citations

  • Method for quickly reducing antibiotics and resistance genes in organic solid waste

    CN108033817A

  • Reinforced removal method for antibiotic resistance genes in aerobic compost

    CN114315441A