A herbicide containing clomazone and cyanazine and its application
By combining dichlorosoxazone with cyanozolin, an active herbicide was formed, and the problem of the increase in resistance to weeds such as polyphylla ryegrass and Arabian grandma. It achieved significant synergistic effect and broad-spectrum herbicide killing effect, delaying the generation of drug resistance.
Patent Information
- Application Number
- CN202411964084.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-30
- Publication Date
- 2025-04-08
AI Technical Summary
The existing herbicides have increased resistance to weeds such as polyphylla ryegrass and Arabian mother-in-law, and have poor prevention efficiency. It is urgently needed for new, efficient and different mechanisms of action.
Combined with dichlorosanone and cyanosamin to form herbicidal active ingredient with a mass ratio of 1:1-50 or 1:3-7, and prepared into herbicide, including auxiliary ingredients such as dispersants, wetting agents, etc., to form water suspension or oil suspension dispersants.
The significant synergistic effect expands the herbicide spectrum, and shows good prevention effects on weeds such as multi-flowered ryegrass and Arabian mother-in-law, delays the generation of drug resistance and improves the service life of herbicides.
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Abstract
Description
Technical Field
[0001] The invention belongs to the technical field of pesticides, and particularly relates to a herbicide containing clomazone and cyanazine and application thereof. Background Art
[0002] Wheat is the main grain crop in my country and plays an important role in the national economy and national food security. Weeds are important pests in wheat growth. They compete with wheat for water, fertilizer, light and space, and breed diseases and insect pests, affecting mechanized wheat harvesting, which seriously threatens wheat yields. In recent years, weeds such as multiflora ryegrass and Arabian Veronica have become more resistant to pesticides. Conventional herbicides have poor control effects on them, and new, efficient herbicides with different mechanisms of action are urgently needed.
[0003] Bixlozone is a selective isoxazolinone herbicide, mainly used in wheat, barley and rapeseed fields to control broadleaf weeds such as cleavers and chickweed, as well as some grass weeds. Bixlozone is a deoxy-D-xylulose phosphate synthase (DOXP) inhibitor. It is absorbed by roots and young shoots, and is transmitted upward to various parts of the plant with transpiration, inhibiting the action of deoxy-D-xylulose phosphate synthase (DOXP), thereby destroying the biosynthesis of plastid isoprenoids, that is, carotenoid synthesis. Carotenoids protect chlorophyll in plant cells and help the photosynthesis process of plants. When carotenoids lose their protective function, the leaves of the plant will turn white. Susceptible weeds cannot metabolize bixlozone, and their leaves turn white, unable to photosynthesize and die.
[0004] Cyanazine is a chlorotriazine herbicide that is systemic and applied in soil and stem and leaf treatments. It is also known as cyanazine, bladex, and bladex. Cyanazine is mainly absorbed by the roots and can also be absorbed through the leaves. It exerts its herbicidal activity by inhibiting photosynthesis, causing the weeds to die. It has a good control effect on various annual grass and broad-leaved weeds in crop fields such as corn, sugarcane, and wheat.
[0005] However, there are still some defects when using clomazone or cyanazine alone to control weeds. For example, clomazone has a high risk of resistance to multiflora ryegrass, and multiflora ryegrass in wheat fields in some parts of my country has developed a moderate level of resistance to clomazone. At the same time, clomazone has a poor control effect on Arabian Veronica, while cyanazine has a poor control effect on multiflora ryegrass.
[0006] The information disclosed in this background technology section is only intended to enhance the understanding of the overall background of the invention and should not be regarded as an acknowledgment or any form of suggestion that the information constitutes the prior art already known to a person skilled in the art. Summary of the invention
[0007] The object of the present invention is to provide a herbicide composition containing clomazone and cyanazine and application thereof.
[0008] To achieve the above object, the present invention provides the following technical solutions:
[0009] The first object of the present invention is to provide an active herbicidal ingredient, wherein the active herbicidal ingredient is compounded with clomazone and cyanazine, and the mass ratio of clomazone to cyanazine is 1:1-50.
[0010] Furthermore, the mass ratio of clomazone to cyanazine is 1:3-7.
[0011] The second object of the present invention is to provide a herbicide, which is prepared from the herbicidal active ingredients and auxiliary ingredients permitted in pesticides.
[0012] Furthermore, the mass of the herbicidal active ingredient accounts for 5-90% of the total mass of the herbicide composition.
[0013] Furthermore, the auxiliary ingredients permitted in pesticide science are selected from one or more of dispersants, wetting agents, thickeners, suspending agents, antifreeze agents, defoaming agents and solvents.
[0014] Furthermore, the herbicide is prepared into an aqueous suspension concentrate from the following ingredients, measured by mass percentage: 4-20% of clomazone, 20-60% of cyanazine, 1-3% of a dispersant, 0.5-4% of a wetting agent, 0.1-0.6% of a thickener, 1-5% of a suspending agent, 2-10% of an antifreeze agent, 0.1-0.5% of a defoaming agent, and the remainder of deionized water.
[0015] Furthermore, the herbicide is prepared into an oil suspension dispersant from the following ingredients, measured by mass percentage: 4-10% of clomazone, 10-40% of cyanazine, 5-15% of a dispersing wetting agent, 1-5% of a thickening suspending agent, 15-30% of a methylated vegetable oil, and the remainder of petroleum solvent.
[0016] The third object of the present invention is to provide the use of the herbicidal active ingredient or the herbicide in controlling annual grass and / or broadleaf weeds in wheat fields.
[0017] Compared with the prior art, the present invention has the following beneficial effects:
[0018] (1) Significant synergistic effect. The present invention mixes clomazone and cyanazine, which exhibits good systemic synergistic effects on both multiflora ryegrass and Arabian ryegrass, and improves the weed control effect compared with a single component.
[0019] (2) Expanding the weed control spectrum. The present invention mixes clomazone with cyanazine, which exhibits good control effects on weeds such as multiflora ryegrass, Arabian ryegrass, foxtail grass, Japanese foxtail grass, sophora japonica, pigweed and chickweed, and has a wide weed control spectrum.
[0020] (3) Delaying the development of drug resistance. The herbicidal mechanisms of action of clomazone and cyanazine are quite different. Mixing these herbicides with different action mechanisms is beneficial to delaying the development and development of drug resistance, helping to extend the service life of the agents, and providing support for the development of new, highly effective herbicides with different action mechanisms. DETAILED DESCRIPTION
[0021] The following is a clear and complete description of the technical solution of the present invention in combination with the embodiments. Obviously, the described embodiments are part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by technicians in this field without creative work are within the scope of protection of the present invention.
[0022] In the following examples, if no specific technology or conditions are specified, the technology or conditions described in the literature in this field or the product instructions are used. If the manufacturer of the reagents or instruments used is not specified, they are all conventional products that can be purchased through regular channels. Unless otherwise specified, the percentage content in all embodiments and experimental examples of the present invention refers to the percentage content by weight.
[0023] In the field trial, 40% cyanamide aqueous suspension was provided by Henan Green Protection Technology Co., Ltd., and 36% clomazone aqueous suspension was produced by Jiangsu Agricultural Reclamation Biochemistry Co., Ltd.
[0024] Synergistic effect test: synergistic effect of clomazone and cyanazine on Lolium multiflorum
[0025] 1. Test Weeds
[0026] Lolium multiflorum, weed seeds were collected from wheat fields in the suburbs of Zhengzhou.
[0027] 2. Test reagents
[0028] 96% clomazone technical and 97% cyanazine technical, both of which come from the laboratory of the Institute of Plant Protection, Henan Academy of Agricultural Sciences.
[0029] 3. Test method: (Refer to "NY / T 1155.4-2006 Pesticide Indoor Bioassay Test Guidelines Herbicides Part 4: Activity Determination Test Stem and Leaf Spray Method")
[0030] 3.1 Take field soil, dry it in the shade, pass it through a 20-mesh sieve, add peat and vermiculite, and mix them evenly in a mass ratio of 3:1:1. Take an appropriate amount of mixed soil and place it in a plastic pot (diameter 8.50cm, height 8.20cm). Germinate multiflora ryegrass until it turns white, sow 10 seeds / pot evenly in the plastic pot, and cover it with 0.5cm of soil. Pour water from the bottom of the plastic pot, and place it in an artificial greenhouse at 25±2C° during the day and 18±2C° at night, and keep the soil moist during the period.
[0031] 3.2 The test agent was first dissolved in dimethyl sulfoxide and then diluted with 0.1% Tween-80 aqueous solution to prepare a single-dose stock solution. Multiple groups of proportions were set up, and each single dose and each group of mixed proportions were diluted with 0.1% Tween-80 aqueous solution in equal proportions to form 5 mass concentration gradients.
[0032] 3.3 When the weed seedlings were cultured to the 3-leaf stage, the stems and leaves were sprayed with the above solution. Each treatment was repeated 4 times, with 1 plastic pot for each repeat. A treatment of spraying 0.1% Tween-80 aqueous solution was set as a blank control. After treatment, the plants were transferred to the original conditions for continued cultivation.
[0033] 3.4 21 days after application, the fresh weight of the aboveground part of the weeds was weighed and the fresh weight control effect was calculated. Then, regression analysis was performed to obtain the toxicity regression equation and calculate the GR. 50 The co-toxicity coefficient of the mixture was calculated using the Sun Yunpei method.
[0034] 4. Calculation method
[0035]
[0036] In the above formula: E--fresh weight control effect (%); C--fresh weight of the aboveground part of the control weeds (g); T--fresh weight of the aboveground part of the treated weeds (g).
[0037] 5. Pharmaceutical evaluation
[0038] The synergistic effect of drug mixing was evaluated based on the co-toxicity coefficient (CTC): CTC ≤ 80 for antagonistic effect, 80 < CTC < 120 for additive effect, and CTC ≥ 120 for synergistic effect. The results are shown in Table 1.
[0039] Table 1 The results of the synergistic effect of clomazone and cyanazine on Lolium multiflorum
[0040]
[0041] From the results in Table 1, it can be seen that when clomazone and cyanazine are used alone, they both have a certain control effect on multifloral ryegrass. 50 The value is 15.67g / mu, and the effect of cyanazine on GR of multiflora ryegrass 50The value was 45.28 g / mu. When clomazone was mixed with cyanazine 1+3, 1+4, 1+5, 1+6 and 1+7, the mixed composition had an effect on the growth of multiflora ryegrass GR 50 The values are 20.38, 17.83, 16.72, 19.71 and 22.47 g / mu, respectively, and the corresponding co-toxicity coefficient CTC values are 150.90-205.95, all of which are greater than 120, indicating that the mixture of clomazone and cyanazine of the present invention has a significant synergistic effect on multiflora ryegrass.
[0042] Example 1 50% clomazone-cyanazine aqueous suspension
[0043] Clomazone 10%, cyanazine 40%, sodium lignin sulfonate 1.5%, sodium dodecyl sulfonate 2%, xanthan gum 0.2%, bentonite 3%, ethylene glycol 8%, and the balance is deionized water.
[0044] Example 260% Clomazone-Cyanazine Aqueous Suspension
[0045] Clomazone 10%, cyanazine 50%, sodium lignin sulfonate 1%, sodium dodecyl sulfonate 2%, urea 2%, xanthan gum 0.1%, light calcium carbonate 2%, ethylene glycol 5%, and the balance is deionized water.
[0046] Example 3 35% clomazone-cyanazine oil dispersion suspension
[0047] Clomazone 5%, cyanazine 30%, OP-7 10%, Teflon-8 0 2%, magnesium aluminum silicate 1.5%, organic bentonite 1%, mixed benzene 10%, and the balance methylated vegetable oil.
[0048] Field trials: controlling weeds in wheat fields
[0049] Field test for controlling weeds in wheat fields, the main weeds are multiflora ryegrass, Arabian Veronica, Chickweed and Artemisia selengensis. Application time: 2-3 tillers of wheat, 3-5 leaf stage of weeds. Use backpack electric sprayer for application, fan-shaped nozzle, water consumption 30kg / mu. Each plot is 20m 2 , repeated 3 times, with water spraying as control. 30 days after the application, 4 points were randomly selected from each plot, 1m 2 , investigate and record the fresh weight of the aboveground part of the weeds, and calculate the weed control effect by fresh weight (same as above). The results are shown in Table 2.
[0050] Table 2 Field test results of the combination of clomazone and cyanazine on wheat field weeds (30 days)
[0051]
[0052] As shown in Table 2, 40% cyanazine water suspension 180g / mu (provided by Henan Green Protection Technology Co., Ltd.) and 36% clomazone water suspension 40g / mu have poor control effects on multiflora ryegrass, but good control effects on chickweed; 40% cyanazine water suspension 180g / mu has good control effect on Arabian Veronica, and 36% clomazone water suspension 40g / mu has moderate control effect on Arabian Veronica. 50% clomazone cyanazine water suspension 90-150g / mu and 35% clomazone cyanazine oil dispersion suspension 150-200g / mu have good control effects on multiflora ryegrass, Arabian Veronica and chickweed, and the control effects are all above 85%, showing good high efficiency and broad spectrum, indicating that the combination of clomazone and cyanazine has good application value in wheat field weed control.
[0053] The foregoing description of specific exemplary embodiments of the present invention is for the purpose of illustration and demonstration. These descriptions are not intended to limit the present invention to the precise form disclosed, and it is clear that many changes and variations can be made based on the above teachings. The purpose of selecting and describing the exemplary embodiments is to explain the specific principles of the present invention and its practical application, so that those skilled in the art can realize and utilize various different exemplary embodiments of the present invention and various different selections and changes. The scope of the present invention is intended to be limited by the claims and their equivalents.
Claims
1. A herbicidal active ingredient, characterized in that The herbicidal active ingredient is compounded by clomazone and cyanazine, and the mass ratio of clomazone to cyanazine is 1:1-50.
2. The herbicidal active ingredient according to claim 1, characterized in that The mass ratio of clomazone to cyanazine is 1:3-7.
3. A herbicide, characterized in that: The herbicide is prepared from the herbicidal active ingredient according to claim 1 and auxiliary ingredients permitted in pesticides.
4. The herbicide according to claim 3, characterized in that The mass of the herbicidal active ingredient accounts for 5-90% of the total mass of the herbicide composition.
5. The herbicide according to claim 3, characterized in that The auxiliary ingredients permitted in pesticide science are selected from one or more of dispersants, wetting agents, thickeners, suspending agents, antifreeze agents, defoaming agents and solvents.
6. The herbicide composition according to claim 3, characterized in that The herbicide is prepared from the following ingredients by mass percentage: 4-20% of clomazone, 20-60% of cyanazine, 1-3% of dispersant, 0.5-4% of wetting agent, 0.1-0.6% of thickener, 1-5% of suspending agent, 2-10% of antifreeze agent, 0.1-0.5% of defoamer, and the balance of deionized water.
7. The herbicide according to claim 6, characterized in that The formulation of the herbicide is a water suspension.
8. The herbicide composition according to claim 3, characterized in that The herbicide is prepared from the following ingredients by mass percentage: 4-10% of clomazone, 10-40% of cyanazine, 5-15% of a dispersing and wetting agent, 1-5% of a thickening and suspending agent, 15-30% of a methylated vegetable oil, and the remainder of petroleum solvent.
9. The herbicide according to claim 8, characterized in that The formulation of the herbicide is an oil suspension dispersant.
10. Use of the herbicidal active ingredient according to any one of claims 1 to 2 or the herbicide according to any one of claims 3 to 9 for controlling annual grass and / or broadleaf weeds in wheat fields.