Precise medicine applying device for esophagus

Abstract

The invention relates to the technical field of esophagus medicine applying devices, in particular to an accurate esophagus medicine applying device which comprises an external catheter, one end of the external catheter is connected with a holding handle, the other end of the external catheter is connected with a medicine applying pipe through a cylindrical sliding film, and a medicine applying nozzle is arranged at the tail end of the medicine applying pipe. The barrel-shaped sliding film wraps the drug delivery pipe so that the esophagus can be separated from the drug delivery pipe, the drug delivery pipe does not rub with mucous membranes in the esophagus when moving in the esophagus, the barrel-shaped sliding film is gradually attached to the interior of the esophagus, and the barrel-shaped sliding film attached to the interior of the esophagus is static relative to the interior of the esophagus. The dosing tube can reach a designated position by relatively moving in the cylindrical sliding film, and when the dosing tube moves to a lesion position, the dosing nozzle can be controlled to spray liquid medicine, so that the discomfort of a patient is reduced, and the dosing precision is prevented from being influenced.

Description

Technical Field

[0001] The present invention relates to the technical field of esophageal medicine delivery devices, and in particular to an esophageal precise medicine delivery device. Background Art

[0002] Esophageal drug delivery device usually refers to the use of medical equipment such as endoscopes to accurately deliver drugs to a certain part of the esophagus. It is mostly used to treat esophageal diseases, such as esophageal cancer, esophageal ulcers, etc. Generally speaking, the drug can be an anticancer drug, antibacterial drug, or anti-inflammatory drug for local treatment. The device can accurately deliver the drug to the part that needs treatment through endoscope guidance. The use of endoscopic operation can minimize damage to surrounding tissues and improve the efficacy and safety of the drug.

[0003] For example, Chinese patent CN221905315U discloses an esophageal drug delivery device, which includes a drug outlet hole opened on the outer wall of a drug delivery tube and a drug injector detachably connected to the drug delivery tube, a connector connected to the head end of the drug delivery tube, and the connector is threadedly connected to the drug outlet nozzle of the drug injector, and an air bag for blocking the esophagus is connected to the tail end of the drug delivery tube, and an inflation tube is connected to the side of the air bag close to the drug outlet hole, and the tail end of the inflation tube extends to the outside of the drug injector. The solution arranges the air bag on the drug delivery tube. When the drug is sprayed to the affected part of the inner wall of the esophagus along the drug outlet hole, the air bag is inflated through the inflation tube to make it swell and fit the inner wall of the esophagus, so that the affected part of the esophagus can absorb the drug.

[0004] However, the drug delivery tube in the above scheme will inevitably rub against the internal mucosa of the esophagus when entering the esophagus, which may easily cause discomfort to the patient and affect the medication operation. In severe cases, it may damage the mucosa in the esophagus and aggravate the patient's condition. Summary of the invention

[0005] Based on this, it is necessary to provide an esophageal precise drug delivery device to address the problem that the current esophageal drug delivery device is prone to friction with the esophageal mucosa during drug delivery.

[0006] The above purpose is achieved through the following technical solutions: A precise esophageal medication device comprises an external catheter, one end of which is connected to a gripping handle, the other end of which is coaxially connected to a medication tube, the medication tube is communicated with the external catheter, a plurality of medication nozzles are arranged at the end of the medication tube, the medication tube can extend into the esophagus, a cylindrical synovial membrane is connected between the medication tube and the external catheter, one end of the cylindrical synovial membrane is fixedly connected to the external catheter, the other end of the cylindrical synovial membrane passes through the outer periphery of the medication tube, passes the end of the medication tube and is fixed to the medication tube after forming a plurality of folds, a sealed cavity is formed between the cylindrical synovial membrane and the outer wall of the medication tube, the increase in air pressure inside the sealed cavity can push the medication tube forward in the esophagus and expand the folds of the cylindrical synovial membrane.

[0007] Furthermore, the external catheter is connected to an external fixing plate at one end close to the drug administration tube, and the external fixing plate can prevent the external catheter from entering the esophagus. A connecting tube is provided in the middle of the external fixing plate, one end of the connecting tube is coaxial with the external catheter and fixedly connected, and the other end of the connecting tube is sealed and connected to the tubular synovial membrane.

[0008] Furthermore, an air inlet and an air outlet are provided on the side wall of the connecting tube, and both the air inlet and the air outlet are connected to the sealed cavity. Gas enters the sealed cavity through the air inlet to increase the air pressure inside the sealed cavity. When the air pressure inside the sealed cavity exceeds a preset value, the air outlet opens.

[0009] Furthermore, a regulating valve core is provided on the air vent, and the regulating valve core can adjust the air pressure required when the air vent is opened. The regulating valve core includes a first adjusting screw, and an elastic member is provided on the end of the first adjusting screw. A blocking ball is fixedly provided on the other end of the elastic member, and the blocking ball blocks the air vent.

[0010] Furthermore, a support frame is coaxially arranged on the dosing tube near the end, and a sealing ring is arranged on the support frame near the end of the dosing tube. The cylindrical synovial membrane passes through the outer periphery of the support frame and bypasses the sealing ring to be sealed and connected to the inside of the support frame. The pleated part is located between the support frame and the dosing tube.

[0011] Furthermore, the support frame includes a support ring and a plurality of grab bars, the support ring is connected to the outer periphery of the drug delivery tube, the plurality of grab bars are evenly distributed circumferentially on the support ring and are all hingedly arranged, the sealing ring is abutted against the outer wall of the end of the drug delivery tube by the plurality of grab bars, and a torsion spring is arranged at the hinge position of the plurality of grab bars and the support ring, the torsion spring enables the other end of the plurality of grab bars to abut against the sealing ring, and the sealing ring abuts a part of the cylindrical synovial membrane against the outer wall of the end of the drug delivery tube.

[0012] Furthermore, the drug delivery tube is provided with an adjustment component, which can adjust the contact force of the sealing ring against the cylindrical synovial membrane, and the speed at which the drug delivery tube advances inside the esophagus is negatively correlated with the contact force of the sealing ring against the cylindrical synovial membrane.

[0013] Furthermore, the adjustment component includes a fixed ring sleeve and a limiting ring sleeve, the fixed ring sleeve is coaxial and fixedly arranged on the outer periphery of the drug delivery tube, the limiting ring sleeve is coaxial and fixedly arranged on the outer periphery of the fixed ring sleeve, the support ring of the support frame is slidably arranged on the fixed ring sleeve and is located above the limiting ring sleeve, the support ring can move axially along the fixed ring sleeve, the outer periphery of the end of the drug delivery tube is a conical surface with the small end facing downward, the sealing ring abuts the cylindrical synovial membrane on the conical surface, and the axial movement of the support ring along the fixed ring sleeve can drive the sealing ring to move axially on the conical surface.

[0014] Furthermore, a convex ring is coaxially and fixedly arranged on the outer circumference of the fixed ring sleeve, and a second adjusting screw is axially threadedly connected to the end face of the convex ring. The other end of the second adjusting screw is rotatably connected to the end face of the support ring. The rotation of the second adjusting screw can drive the support ring to move axially along the fixed ring sleeve.

[0015] Furthermore, a camera and a clamp are arranged at the end of the drug delivery tube.

[0016] The beneficial effects of the present invention are: The present invention separates the esophagus and the drug delivery tube by setting a cylindrical synovial membrane, so that when the drug delivery tube moves in the esophagus, it does not generate friction with the internal mucosa of the esophagus, but gradually fits the cylindrical synovial membrane to the inside of the esophagus, and the cylindrical synovial membrane fitted to the inside of the esophagus is relatively still with the inside of the esophagus. The drug delivery tube is relatively moved in the cylindrical synovial membrane so that the drug delivery tube can reach a specified position, and the outer periphery of the cylindrical synovial membrane is also coated with lubricating oil, so it is also possible to avoid damaging the esophagus when the cylindrical synovial membrane is fitted to the inside of the esophagus. When the drug delivery tube moves to the lesion position, the drug delivery nozzle can be controlled to spray the medicine solution, thereby reducing the patient's discomfort and avoiding affecting the accuracy of drug delivery.

[0017] The present invention can avoid sudden change in shape of the tubular synovial membrane caused by excessive pressure in the sealed cavity by arranging the air leakage port, thereby preventing the tubular synovial membrane from damaging the esophagus.

[0018] The present invention is provided with an adjusting valve core, so that the air pressure value required when the air is released from the air release port can be adjusted, and then it can be adjusted according to the different inner diameters of the esophagus of the patient, thereby improving the application range of the esophageal precision medicine dispenser.

[0019] The present invention provides an adjustment component, which can adjust the speed of the drug delivery tube moving in the esophagus, thereby improving the efficiency and accuracy of drug delivery to the drug delivery tube. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 A schematic diagram of the structure of an esophageal precision medicine dispenser provided in one embodiment of the present invention; Figure 2 This is an exploded view of the esophageal precision medicine dispenser provided by one embodiment of the present invention without the external catheter and the holding handle; Figure 3 A schematic diagram of the structure of the esophageal precise medicine dispenser provided by one embodiment of the present invention from another angle; Figure 4 for Figure 3 A cross-sectional view of the esophageal precision medicine dispenser along AA provided in one embodiment; Figure 5 for Figure 4 A partial enlarged view of part X of the esophageal precise medication delivery device provided in the first embodiment; Figure 6 A schematic diagram of the structure of the esophageal precise medication dispenser provided by one embodiment of the present invention from another angle; Figure 7 for Figure 6 A cross-sectional view of the esophageal precision medicine dispenser provided in an embodiment of the present invention along the BB; Figure 8 for Figure 7 A partial enlarged view of the Y portion of the esophageal precision medicine dispenser provided in the first embodiment; Fig. 9 for Figure 8 A partial enlarged view of the esophageal precise medication delivery device U provided in the first embodiment; Fig.10 for Figure 8 A partial enlarged view of part V of the esophageal precise medication delivery device provided in the first embodiment; Fig.11 for Figure 8 A partial enlarged view of the esophageal precise medicine delivery device W provided in the first embodiment; Fig.12 An axonometric view of a cutaway support ring of an esophageal precision medicine dispenser provided in one embodiment of the present invention; Fig.13 A schematic diagram of the structure of a single grab bar of the esophageal precision medicine dispenser provided in one embodiment of the present invention.

[0021] in: 100, grip handle; 110, liquid medicine cylinder; 120, external conduit; 130, first annular groove; 140, first sealing gasket; 150, external fixing plate; 151, connecting tube; 160, air inlet; 161, valve ball; 170, air vent; 171, first adjusting screw; 172, stopper ball; 173, elastic member; 200, cylindrical synovial membrane; 201, folded portion; 210, drug delivery tube; 211, drug delivery nozzle; 212, conical surface; 220, support ring; 221, hinge groove; 222, first fixing groove; 223, hinge column; 224, second ring groove; 225, second sealing gasket; 230, grab bar; 231, matching groove; 232, second fixing groove; 233, grab hook; 240, torsion spring; 250, sealing ring; 260, sealing cavity; 300, fixed ring sleeve; 310, limiting ring sleeve; 320, convex ring; 330, second adjusting screw; 340, rotating ring; 400. Camera; 410. Clamp. DETAILED DESCRIPTION

[0022] In order to make the purpose, technical solution and advantages of the present invention more clearly understood, the present invention is further described in detail below through embodiments and in conjunction with the accompanying drawings. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0023] The serial numbers assigned to the components herein, such as "first", "second", etc., are only used to distinguish the objects described and do not have any order or technical meaning. The "connection" and "coupling" mentioned in the present invention, unless otherwise specified, include direct and indirect connections (couplings). In the description of the present invention, it should be understood that the terms "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", etc., indicating the orientation or position relationship are based on the orientation or position relationship shown in the accompanying drawings, which is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation to the present invention.

[0024] In the present invention, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being "above", "above" or "above" a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being "below", "below" or "below" a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0025] Refer to the following Figure 1-Figure 13 To describe an esophageal precision medicine dispenser provided by the present invention.

[0026] An esophageal precision medicine applicator is suitable for the treatment of esophageal diseases, comprising an external catheter 120, one end of which is connected to a gripping handle 100, the gripping handle 100 is used for an operator to grip, the other end of the external catheter 120 is coaxially connected to a drug delivery tube 210, the drug delivery tube 210 is communicated with the external catheter 120, a plurality of drug delivery nozzles 211 are arranged at the end of the drug delivery tube 210, the external catheter 120 delivers liquid medicine to the drug delivery tube 210, the liquid medicine is sprayed from the plurality of drug delivery nozzles 211, when the drug delivery tube 210 reaches the lesion position inside the esophagus, the operator controls the gripping handle 100 to deliver the liquid medicine, so that the liquid medicine can be accurately sprayed on the lesion position, thereby completing the medicine application operation.

[0027] In the prior art, the drug delivery tube 210 is generally inserted into the patient's esophagus together with the external catheter 120, and lubricating oil is also applied to the outer periphery of the external catheter 120 and the drug delivery tube 210. However, when the external catheter 120 and the drug delivery tube 210 are inserted into the esophagus together and friction is generated, even if lubricating oil is applied, it will cause discomfort to the patient, thereby affecting the accuracy of the drug delivery operation. In the present invention, a cylindrical synovial membrane 200 is connected between the external catheter 120 and the drug delivery tube 210, one end of the cylindrical synovial membrane 200 is connected to the end of the external catheter 120 close to the drug delivery tube 210, and the other end of the cylindrical synovial membrane 200 passes through the outer periphery of the drug delivery tube 210, that is, the outer periphery of the drug delivery tube 210 is wrapped, and then the cylindrical synovial membrane 200 is connected to the outer periphery of the drug delivery tube 210. The other end will pass through the end of the outer periphery of the dosing tube 210 and form a plurality of folds, that is, it has a folded portion 201, and is then fixed on the dosing tube 210. At this time, there is a sealed cavity 260 between the tubular synovial membrane 200 and the dosing tube 210. The outer periphery of the tubular synovial membrane 200 is also coated with lubricating oil, and when the air pressure in the sealed cavity 260 increases, it can push the dosing tube 210 forward in the esophagus. The tubular synovial membrane 200 fits with the inside of the esophagus and does not produce relative movement. In the process of the dosing tube 210 moving forward, the folded portion 201 of the tubular synovial membrane 200 is gradually stretched open, thereby continuously fitting the tubular synovial membrane 200 of the folded portion 201 to the inside of the esophagus, thereby preventing the dosing tube 210 from rubbing against the inside of the esophagus.

[0028] By setting the above-mentioned cylindrical synovial membrane 200, the esophagus and the drug delivery tube 210 are separated, so that when the drug delivery tube 210 moves in the esophagus, it does not generate friction with the internal mucosa of the esophagus, but the cylindrical synovial membrane 200 is gradually attached to the inside of the esophagus, and the cylindrical synovial membrane 200 attached to the inside of the esophagus is relatively still with the inside of the esophagus. The drug delivery tube 210 is relatively moved in the cylindrical synovial membrane 200 so that the drug delivery tube 210 can reach the specified position, and the outer periphery of the cylindrical synovial membrane 200 is also coated with lubricating oil, so it can also avoid damaging the esophagus when the cylindrical synovial membrane 200 is attached to the inside of the esophagus. When the drug delivery tube 210 moves to the lesion position, the drug delivery nozzle 211 can be controlled to spray the medicine, thereby reducing the patient's discomfort and avoiding affecting the accuracy of drug application.

[0029] Specifically, an external fixing plate 150 is connected to one end of the external catheter 120 close to the drug delivery tube 210. The external fixing plate 150 is used to prevent the external catheter 120 from entering the esophagus. Figure 8 and Fig. 9 As shown, the external fixing plate 150 has a connecting tube 151 in the middle, one end of the connecting tube 151 is coaxially and fixedly connected to the end of the external catheter 120 close to the drug delivery tube 210, and the other end of the connecting tube 151 is sealed and connected to one end of the tubular synovial membrane 200, specifically through the first sealing gasket 140. Fig. 9 As shown, a first annular groove 130 is formed on one end of the connecting tube 151 close to the cylindrical sliding membrane 200, and one end of the cylindrical sliding membrane 200 is located in the first annular groove 130, and the first sealing gasket 140 tightly abuts one end of the cylindrical sliding membrane 200 in the first annular groove 130 to achieve a sealing connection.

[0030] More specifically, Figure 8 and Fig. 9 As shown, an air inlet 160 and an air vent 170 are provided on the side wall of the connecting tube 151. The air inlet 160 is used to transport gas into the sealed cavity 260. The gas entering the sealed cavity 260 can increase the air pressure in the sealed cavity 260, thereby pushing the drug delivery tube 210 forward inside the esophagus. The air vent 170 is used to prevent the air pressure in the sealed cavity 260 from being too high and causing a sudden change in the shape of the tubular synovial membrane 200, thereby preventing the tubular synovial membrane 200 from damaging the esophageal mucosa.

[0031] It can be understood that when the air pressure in the sealed cavity 260 reaches a certain value, it can push the drug delivery tube 210 forward inside the esophagus, so the limit value (preset value) is set to be slightly larger than the air pressure required to push the drug delivery tube 210 forward. When the air pressure in the sealed cavity 260 is greater than the limit value, the vent 170 will open to avoid excessive air pressure in the sealed cavity 260.

[0032] It should be noted that the air inlet 160 of the present invention can only take in air in one direction and cannot release air to the outside. Fig. 9 As shown, a valve ball 161 is arranged in the air inlet 160, and a compression spring is connected to the bottom of the valve ball 161, and one end of the compression spring abuts against the lower end of the air inlet 160. In the initial state, the valve ball 161 blocks the upper end of the air inlet 160 through the compression spring. Only when air is inflated into the air inlet 160 and the air pressure increases to overcome the compression spring, the valve ball 161 moves downward to open the air inlet 160, and the gas can enter the sealed cavity 260 through the air inlet 160. The one-way air inlet setting makes the gas pressure entering the sealed chamber constant and is relatively stable during the gas input process.

[0033] Specifically, the air inlet 160 in this embodiment is connected to a micro air pump (not shown in the figure), and the micro air pump is used to transport the gas into the sealed chamber.

[0034] In a further embodiment, in order to increase the scope of application of the esophageal precision medicine applicator, an adjusting valve core is provided on the air vent 170, and the adjusting valve core can adjust the air pressure required to open the air vent 170, that is, the limit value of the sealed cavity 260 can be adjusted. Because the inner diameter of the esophagus of different patients is different, some patients have a smaller inner diameter of the esophagus, while some patients have a larger inner diameter of the esophagus, so the limit value of the sealed cavity 260 can be changed by adjusting the valve core to adapt to esophagi of different inner diameters, thereby increasing the scope of application of the esophageal precision medicine applicator.

[0035] Specifically, Figure 8 and Fig. 9 As shown, the regulating valve core includes a first regulating screw 171, which is spirally connected to the outside of the air leakage port 170, and the bottom end of the first regulating screw 171 is connected to an elastic member 173, which can be a compression spring, and the other end of the elastic member 173 is fixedly connected to a blocking ball 172, which blocks the air leakage port 170. When the gas pressure in the sealing cavity 260 can overcome the elastic force of the elastic member 173, the blocking ball 172 can be pushed to open the air leakage port 170, and by rotating the first regulating screw 171, the air leakage port 170 is opened. The joint screw 171 can adjust the compression degree of the elastic member 173. When the compression degree of the elastic member 173 is greater, the limit value of the sealed cavity 260 is greater. Only when the air pressure in the sealed cavity 260 exceeds the greater limit value can the ball 172 be pushed to open the vent 170. Similarly, when the compression degree of the elastic member 173 is smaller, the limit value of the sealed cavity 260 is smaller. Only when the air pressure in the sealed cavity 260 exceeds the smaller limit value can the ball 172 be pushed to open the vent 170. It should be noted that the minimum limit value also needs to be greater than the pressure value required to push the drug delivery tube 210 forward in the esophagus, so as to avoid the phenomenon that the gas is directly discharged from the vent 170 and cannot push the drug delivery tube 210 forward in the esophagus.

[0036] Specifically, a support frame is coaxially arranged near the end of the dosing tube 210, and a sealing ring 250 is connected to the support frame near the end of the dosing tube 210. The sealing ring 250 abuts against the end of the dosing tube 210. Figure 8 and Fig.11As shown, the cylindrical synovial membrane 200 passes through the sealing ring 250 after passing through the periphery of the support frame, and is abutted against the periphery of the end of the drug delivery tube 210 by the sealing ring 250. The folded portion 201 of the cylindrical synovial membrane 200 is formed after passing through the sealing ring 250. By folding the cylindrical synovial membrane 200, the space between the sealing ring 250 and the support frame can store more cylindrical synovial membrane 200, thereby allowing the drug delivery tube 210 to move a longer distance in the esophagus.

[0037] More specifically, in this embodiment, the support frame includes a support ring 220 and a plurality of grab bars 230, such as Figure 2 , Fig.10 , Fig.12 and Fig.13 As shown, the support ring 220 is connected to the outer circumference of the drug delivery tube 210, and multiple grab bars 230 are evenly arranged on the support ring 220 in the circumferential direction and are all hinged. A torsion spring 240 is arranged at the position where the multiple grab bars 230 are hinged to the support ring 220. The torsion spring 240 can make the other ends of the multiple grab bars 230 approach each other, and the other ends of the multiple grab bars 230 are provided with a grab hook 233, and the grab hook 233 abuts the sealing ring 250. The setting of the torsion spring 240 allows the grab hook 233 to always abut the sealing ring 250, and the sealing ring 250 always abuts the cylindrical synovial membrane 200 on the outer circumference of the end of the drug delivery tube 210, thereby giving the cylindrical synovial membrane 200 a certain friction force. When the air pressure in the sealing cavity 260 increases, the gas pushes the drug delivery tube. 210 moves forward in the esophagus, and the sealing ring 250 synchronously follows the movement of the dosing tube 210. Since the external catheter 120 is positioned outside, the external catheter 120 does not move, and only the dosing tube 210 moves forward in the esophagus. Therefore, the dosing tube 210 can pull the folded part 201 of the tubular synovial membrane 200 through the sealing ring 250 during the moving forward process, and the sealing ring 250 gives a certain friction force so that the tubular synovial membrane 200 on the periphery of the dosing tube 210 is straightened, and at the same time, the length of the tubular synovial membrane 200 on the periphery of the dosing tube 210 is increased. That is to say, the tubular synovial membrane 200 on the periphery of the dosing tube 210 is gradually attached to the inner wall relative to the inner wall of the esophagus, and the two do not produce relative movement, thereby reducing the patient's discomfort.

[0038] To facilitate sealing of the other end of the cylindrical sliding membrane 200, the other end of the cylindrical sliding membrane 200 is sealed and connected to the support ring 220, such as Fig.10 As shown, a second annular groove 224 is opened at an internal position near the hinge of multiple grab bars 230 on the sealing ring 250, and the other end of the cylindrical sliding membrane 200 is located in the second annular groove 224, and a second sealing gasket 225 is clamped in the second annular groove 224, and the second sealing gasket 225 tightly connects the other end of the cylindrical sliding membrane 200 in the second annular groove 224.

[0039] Specifically, to facilitate the connection of the torsion spring 240, as Figure 2 , Fig.12 and Fig.13 As shown, a hinge groove 221 is provided on the support ring 220, a hinge column 223 is arranged in the hinge groove 221, a first fixed groove 222 is also arranged near the hinge column 223, a matching groove 231 is provided on the grab bar 230, the matching groove 231 is rotatably connected to the hinge column 223 in the hinge groove 221, a second fixed groove 232 is arranged in the matching groove 231, and two ends of the torsion spring 240 are respectively fixedly connected in the first fixed groove 222 and the second fixed groove 232, so that the torsion spring 240 is connected at the hinge position of multiple grab bars 230.

[0040] In a further embodiment, in order to adjust the moving speed of the dosing tube 210 in the esophagus to improve the efficiency and accuracy of drug delivery, an adjustment component is provided on the dosing tube 210, and the adjustment component is used to adjust the abutment force of the sealing ring 250 on the cylindrical synovial membrane 200, thereby adjusting the friction force of the sealing ring 250 on the cylindrical synovial membrane 200. Since the dosing tube 210 needs to open the cylindrical synovial membrane 200 of the folded part 201 when pushed by gas, and this part of the cylindrical synovial membrane 200 needs to pass through the sealing ring 250, and the sealing ring 250 abuts against the cylindrical synovial membrane 200, when the friction force between the sealing ring 250 and the cylindrical synovial membrane 200 is different, the speed at which the dosing tube 210 moves in the esophagus is different, that is, the force of the gas pushing the dosing tube 210 to move does not change, and the dosing tube 210 is pushed by gas. Different forces act on the cylindrical synovial membrane 200, thereby changing the moving speed of the dosing tube 210, and the speed at which the dosing tube 210 advances inside the esophagus is negatively correlated with the abutment force of the sealing ring 250 on the cylindrical synovial membrane 200. In other words, the greater the abutment force of the sealing ring 250 on the cylindrical synovial membrane 200, the greater the friction force of the sealing ring 250 on the cylindrical synovial membrane 200, which makes the resistance encountered by the dosing tube 210 when advancing in the esophagus greater, and thus makes the speed of the dosing tube 210 advancing in the esophagus slower; similarly, the smaller the abutment force of the sealing ring 250 on the cylindrical synovial membrane 200, the smaller the friction force of the sealing ring 250 on the cylindrical synovial membrane 200, the smaller the resistance encountered by the dosing tube 210 when advancing in the esophagus, and thus makes the speed of the dosing tube 210 advancing in the esophagus faster.

[0041] Specifically, the adjustment component includes a fixed ring sleeve 300 and a limiting ring sleeve 310. The fixed ring sleeve 300 is coaxially and fixedly arranged on the periphery of the drug delivery tube 210. The support ring 220 of the support frame is slidably sleeved on the periphery of the fixed ring sleeve 300. The support ring 220 can move axially along the fixed ring sleeve 300 on the periphery of the fixed ring sleeve 300. The limiting ring sleeve 310 is coaxially and fixedly arranged on the periphery of the fixed ring sleeve 300 and is located below the support ring 220 to limit the maximum distance of the axial downward movement of the support ring 220. To prevent the support ring 220 from separating from the fixed ring sleeve 300, a convex ring 320 is coaxially and fixedly connected to the upper end of the outer circumference of the fixed ring sleeve 300. The convex ring 320 can limit the maximum distance of the axial upward movement of the support ring 220, and a second adjusting screw 330 is threadedly connected to the outer circumferential end surface of the convex ring 320. The other end of the second adjusting screw 330 is rotatably connected to the support ring 220, specifically connected to the support ring 220 through a rotating ring 340. When the second adjusting screw 330 rotates, the support ring 220 can be adjusted. 20 is an axial position on the fixed ring sleeve 300. The outer wall of the end of the drug delivery tube 210 in this embodiment is a conical surface 212, and the small end faces downward. Therefore, when the support ring 220 moves axially upward on the fixed ring sleeve 300, it can synchronously drive the multiple grab bars 230 to move upward synchronously. The grab hooks 233 on the multiple grab bars 230 drive the sealing ring 250 to move upward on the conical surface 212. The sealing ring 250 in this embodiment is elastic. When the sealing ring 250 moves upward on the conical surface 212, elasticity occurs. Deformation increases the abutment force on the cylindrical synovial membrane 200, and the friction force on the cylindrical synovial membrane 200 increases, thereby slowing down the movement speed of the drug delivery tube 210 in the esophagus; similarly, when the support ring 220 moves axially downward on the fixed ring sleeve 300, it drives the multiple grab bars 230 to move downward. At this time, the sealing ring 250 moves downward under the action of its own elasticity, and the friction force of the sealing ring 250 on the cylindrical synovial membrane 200 is reduced, thereby increasing the movement speed of the drug delivery tube 210 in the esophagus.

[0042] In a further embodiment, in order to observe the condition of the internal mucosa of the esophagus when the drug administration tube 210 moves in the esophagus, a camera 400 is further provided at the end of the drug administration tube 210, and the camera 400 can record the condition of the internal mucosa of the esophagus.

[0043] Specifically, a clamp 410 is provided at the end of the drug delivery tube 210. The clamp 410 is used for sampling. If other lesions occur in the internal mucosa of the esophagus, the clamp 410 can be used to clamp part of the tissue in the lesion area. After taking out this part of the tissue and testing it, the cause of the lesion can be known.

[0044] More specifically, a medicine liquid cartridge 110 is connected to the gripping handle 100, and the medicine liquid cartridge 110 is communicated with an external conduit 120. A micro pump (not shown in the figure) is provided in the medicine liquid cartridge 110, and the micro pump can deliver the medicine liquid in the medicine liquid cartridge 110 into the external conduit 120. The medicine liquid enters the dosing tube 210 through the external conduit 120, and is then sprayed out from the dosing nozzle 211 through the dosing tube 210.

[0045] The specific working process of the esophageal precise medicine dispenser provided by the present invention is described in combination with the above embodiments: When the dosing tube 210 has not entered the esophagus initially, the dosing tube 210 and the external catheter 120 are very close to each other, the cylindrical synovial membrane 200 between the dosing tube 210 and the external catheter 120 is relatively short, and most of the cylindrical synovial membrane 200 is folded between the multiple grab bars 230 and the dosing tube 210. Before applying the medicine into the esophagus, lubricating oil is applied to the outer periphery of the cylindrical synovial membrane 200, and then the dosing tube 210 is inserted into the esophagus from the patient's mouth. The external fixing plate 150 on the external catheter 120 is fixed through the patient's mouth, and the first adjusting screw 171 is rotated according to the inner diameter of the patient's esophagus to adjust the air pressure required for the deflation of the deflation port 170, and the friction of the sealing ring 250 on the cylindrical synovial membrane 200 is adjusted according to the patient's condition to adjust the forward speed of the dosing tube 210 in the esophagus.

[0046] Start the micro air pump (not shown in the figure), which delivers gas to the air inlet 160. The gas pressure in the sealed cavity 260 gradually increases, thereby pushing the drug delivery tube 210 forward in the esophagus, and in the process of moving forward, the folded cylindrical synovial membrane 200 is stretched open so as to fit inside the esophagus, so that the inside of the esophagus and the cylindrical synovial membrane 200 are relatively still, while the drug delivery tube 210 moves relative to the cylindrical synovial membrane 200, and the drug delivery tube 210 is separated from the inside of the esophagus by the cylindrical synovial membrane 200, thereby reducing the discomfort caused to the patient by the movement of the drug delivery tube 210.

[0047] When the dosing tube 210 moves forward in the esophagus, the camera 400 can be used to observe the situation inside the esophagus. When it reaches the medication area, the operator injects liquid medicine into the dosing tube 210 through the external catheter 120, and the liquid medicine is sprayed out through the dosing nozzle 211 at the end of the dosing tube 210. If other diseased areas are encountered, the clamp 410 can be used to clamp part of the tissue in other diseased areas and remove this part of the tissue for laboratory analysis to determine the cause of the disease, and other drugs can be used to treat the diseased area.

[0048] The technical features of the above embodiments may be combined arbitrarily. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0049] The above-described embodiments only express several implementation methods of the present invention, and the description thereof is relatively specific and detailed, but it cannot be understood as limiting the scope of the present invention. It should be pointed out that, for a person of ordinary skill in the art, several modifications and improvements can be made without departing from the concept of the present invention, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the attached claims.

Claims

1. An esophageal precision medicine dispenser, characterized in that: It includes an external catheter, one end of which is connected to a holding handle, the other end of which is coaxially connected to a drug administration tube, the drug administration tube is communicated with the external catheter, a plurality of drug administration nozzles are arranged at the end of the drug administration tube, the drug administration tube can extend into the esophagus, a cylindrical synovial membrane is connected between the drug administration tube and the external catheter, one end of the cylindrical synovial membrane is fixedly connected to the external catheter, the other end of the cylindrical synovial membrane passes through the outer periphery of the drug administration tube, passes the end of the drug administration tube and is fixed to the drug administration tube after forming a plurality of folds, a sealed cavity is formed between the cylindrical synovial membrane and the outer wall of the drug administration tube, the increase in air pressure inside the sealed cavity can push the drug administration tube forward in the esophagus and expand the folds of the cylindrical synovial membrane.

2. The esophageal precise medicine dispenser according to claim 1, characterized in that: An external fixing plate is connected to one end of the external catheter close to the drug delivery tube, and the external fixing plate can prevent the external catheter from entering the esophagus. A connecting tube is provided in the middle of the external fixing plate, one end of the connecting tube is coaxial with the external catheter and fixedly connected, and the other end of the connecting tube is sealingly connected to the tubular synovial membrane.

3. The esophageal precise medicine dispenser according to claim 2, characterized in that: An air inlet and an air outlet are provided on the side wall of the connecting tube, and both the air inlet and the air outlet are connected to the sealed cavity. Gas enters the sealed cavity through the air inlet to increase the air pressure inside the sealed cavity. When the air pressure in the sealed cavity exceeds a preset value, the air outlet opens.

4. The esophageal precise medicine dispenser according to claim 3, characterized in that: The air vent is provided with a regulating valve core, which can adjust the air pressure required when the air vent is opened. The regulating valve core includes a first adjusting screw, an elastic member is provided at the end of the first adjusting screw, and a blocking ball is fixedly provided on the other end of the elastic member, and the blocking ball blocks the air vent.

5. The esophageal precise medicine dispenser according to claim 1, characterized in that: A support frame is coaxially arranged on the dosing tube near the end, and a sealing ring is arranged on the support frame near the end of the dosing tube. The cylindrical synovial membrane passes through the outer periphery of the support frame and bypasses the sealing ring to be sealed and connected inside the support frame. The pleated part is located between the support frame and the dosing tube.

6. The esophagus precise medicine dispenser according to claim 5, characterized in that: The support frame includes a support ring and a plurality of grab bars, wherein the support ring is connected to the outer periphery of the drug delivery tube, the plurality of grab bars are evenly distributed circumferentially on the support ring and are all hingedly arranged, the sealing ring is abutted against the outer wall of the end of the drug delivery tube by the plurality of grab bars, and a torsion spring is arranged at the hinge position of the plurality of grab bars and the support ring, the torsion spring enables the other ends of the plurality of grab bars to abut against the sealing ring, and the sealing ring abuts a part of the cylindrical synovial membrane against the outer wall of the end of the drug delivery tube.

7. The esophagus precise medicine dispenser according to claim 6, characterized in that: The drug delivery tube is provided with an adjustment component, which can adjust the contact force of the sealing ring against the cylindrical synovial membrane. The speed at which the drug delivery tube advances inside the esophagus is negatively correlated with the contact force of the sealing ring against the cylindrical synovial membrane.

8. The esophagus precise medicine dispenser according to claim 7, characterized in that: The adjustment component includes a fixed ring sleeve and a limiting ring sleeve, the fixed ring sleeve is coaxial and fixedly arranged on the outer periphery of the drug delivery tube, the limiting ring sleeve is coaxial and fixedly sleeved on the outer periphery of the fixed ring sleeve, the support ring of the support frame is slidably arranged on the fixed ring sleeve and is located above the limiting ring sleeve, the support ring can move axially along the fixed ring sleeve, the outer periphery of the end of the drug delivery tube is a conical surface with the small end facing downward, the sealing ring abuts the cylindrical sliding membrane on the conical surface, and the axial movement of the support ring along the fixed ring sleeve can drive the sealing ring to move axially on the conical surface.

9. The esophagus precise medicine dispenser according to claim 8, characterized in that: A convex ring is coaxially and fixedly provided on the outer circumference of the fixed ring sleeve, and a second adjusting screw is axially threadedly connected to the end face of the convex ring. The other end of the second adjusting screw is rotatably connected to the end face of the support ring. The rotation of the second adjusting screw can drive the support ring to move axially along the fixed ring sleeve.

10. The esophagus precise medicine dispenser according to claim 1, characterized in that: A camera and a clamp are arranged in the end of the drug delivery tube.

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