Sunscreen lotion containing photoresponse material and preparation method of sunscreen lotion

Abstract

The invention provides a sunscreen lotion containing a photoresponse material and a preparation method thereof, and the sunscreen lotion comprises the following components in parts by weight: 20-30 parts of a photoresponse material, 3-5 parts of an anti-inflammatory component, 2-6 parts of an antioxidant component, 4-7 parts of a moisturizing component, 3-6 parts of a plant extract, 0.3-0.8 part of essence and 10-20 parts of water. The photoresponse material is prepared from benzophenone, salicylate and metal oxide according to the mass ratio of 1: (1 to 2): (0.4 to 0.8); the plant extracting solution comprises aloe and a green tea extracting solution in a mass ratio of 1: (2-3). The obtained sunscreen lotion has good sunscreen performance, stability and the like, and is friendly to skin and free of irritation.

Description

Technical Field

[0001] The invention belongs to the technical field of sunscreen lotion preparation, and specifically relates to a sunscreen lotion containing a light-responsive material and a preparation method thereof. Background Art

[0002] The importance of sun protection cannot be ignored, especially in modern life, when people are increasingly aware of the potential harm of ultraviolet (UV) rays to the skin and health. Proper sun protection measures can not only protect the skin from short-term sunburn, but also prevent long-term skin aging and disease.

[0003] Ultraviolet rays in sunlight are divided into UVC (short-wave ultraviolet rays, 200nm-290nm), UVB (medium-wave ultraviolet rays, 290nm-320nm) and UVA (long-wave ultraviolet rays, 320nm-400nm) according to their physiological effects. The UVC that reaches the ground after passing through the ozone layer is very weak, UVB is only partially absorbed by the ozone layer, and UVA is not absorbed at all. The ultraviolet rays projected onto the ground mainly include 10% UVB and 90% UVA, among which UVB has the strongest effect on the skin. Ultraviolet B (UVB) is the main cause of acute sunburn. When the skin is exposed to excessive UVB radiation, the DNA in the skin will be damaged, triggering an inflammatory response, which manifests as redness, swelling, pain and peeling. Sunburn not only causes discomfort, but may also cause damage to the skin barrier function and increase the risk of infection. Severe sunburn may even cause blisters and second-degree burns. Long-term and repeated sunburns will accumulate skin damage, cause DNA mutations in skin cells, and increase the risk of skin cancer. Chronic sunburn can cause the skin to gradually become thinner and lose elasticity, and lead to early signs of aging such as wrinkles and pigmentation.

[0004] Sunscreen is a skin care product used to protect the skin from ultraviolet (UV) damage and is widely used in daily life, especially during outdoor activities. Selecting and using the right sunscreen is essential to preventing sunburn, skin cancer and photoaging. The active substances in some sunscreens have poor stability in aqueous solutions and are easily affected by pH and temperature, causing stratification or even degradation, which results in poor activity of the sunscreen active substances, and even causes discoloration and taste change, poor stability, and high irritation. Summary of the invention

[0005] The purpose of the present invention is to provide a sunscreen lotion containing a photoresponsive material, by adding specific photoresponsive materials, plant extracts and other ingredients into the daily sunscreen lotion formula to further improve the sun protection, stability, etc. of the sunscreen lotion and reduce skin irritation.

[0006] In order to achieve the above object, the present invention provides the following technical solutions: A sunscreen containing a photoresponsive material comprises the following components by weight: 20-30 parts of the photoresponsive material, 3-5 parts of an anti-inflammatory component, 2-6 parts of an antioxidant component, 4-7 parts of a moisturizing component, 3-6 parts of a plant extract, 0.3-0.8 parts of an essence and 10-20 parts of water.

[0007] Furthermore, the photoresponsive material is composed of benzophenone, salicylate and metal oxide in a mass ratio of 1:1-2:0.4-0.8.

[0008] Furthermore, the benzophenone is one of avobenzone and oxybenzone or a mixture thereof; the salicylate is one of cinnamyl salicylate and menthol salicylate or a mixture thereof; and the metal oxide is one of titanium dioxide and zinc oxide or a mixture thereof.

[0009] Furthermore, the benzophenone is a mixture of avobenzone and oxybenzone in a mass ratio of 1:1.2-1.5; the salicylate is a mixture of cinnamyl salicylate and menthol salicylate in a mass ratio of 1:1.5-1.8; and the metal oxide is a mixture of titanium dioxide and zinc oxide in a mass ratio of 1:0.5-0.7.

[0010] Furthermore, the plant extract is an aloe vera and green tea extract in a mass ratio of 1:2-3.

[0011] Furthermore, the anti-inflammatory component is glyceryl caprylate and phenoxyethanol in a mass ratio of 1:1.3-1.6; the antioxidant component is arginine or niacinamide.

[0012] Furthermore, the moisturizing ingredients are lauroyl lysine, shea butter and glycerol in a mass ratio of 1:0.5-0.8:1-1.5.

[0013] A method for preparing a sunscreen lotion containing a light-responsive material, comprising the following steps; S1: Preparation of photoresponsive materials; S2: preparing plant extract; S3: Mix 20-30 parts of the photoresponsive material, 3-5 parts of the anti-inflammatory component and 3-6 parts of the plant extract, and stir continuously for 1-2 hours at a temperature of 55-65°C; S4: Add 2-6 parts of antioxidant ingredients, 4-7 parts of moisturizing ingredients, 0.3-0.8 parts of essence and 10-20 parts of water to step S3, continue stirring for 20-30 minutes; then ultrasonically treat for 30-50 minutes to obtain the sunscreen containing the light-responsive material.

[0014] Furthermore, the preparation process of the photoresponsive material in step S1 is: taking benzophenone, salicylate and metal oxide respectively in a mass ratio of 1:1-2:0.4-0.8, stirring and reacting at a temperature of 45-55°C for 40-60 minutes.

[0015] Furthermore, the preparation process of the plant extract in step S2 is: take aloe vera and green tea according to a mass ratio of 1:2-3, add 10-20 times the weight of ethanol solution thereto, heat the temperature to 80-90°C, stir and reflux for 2-5h, distill and concentrate to 1 / 3 to obtain the plant extract.

[0016] Benzophenone compounds and salicylate compounds absorb ultraviolet rays through n-π* transition and release the energy in the form of heat or fluorescence; they have good absorption capacity for ultraviolet rays in the UVA and UVB bands.

[0017] Nano-TiO2 has a larger surface area and higher reflection efficiency, especially for UVA and UVB. Zinc oxide is also a commonly used physical UV shielding agent, which can reflect and scatter UV light under UV light. Nano-ZnO has a higher reflection efficiency, especially for UVA and UVB.

[0018] Aloe vera is rich in polysaccharides, especially acemannan, which has moisturizing, anti-inflammatory and wound healing effects. Aloe vera contains more than 20 amino acids, 7 of which are essential amino acids for the human body. These amino acids help maintain the elasticity and moisture balance of the skin. Aloe vera is rich in vitamins A, C, E and B vitamins, especially vitamin E, which has a strong antioxidant effect, can neutralize free radicals and delay skin aging. Aloe vera contains a variety of minerals, such as calcium, magnesium, zinc, iron, etc., which help maintain the health of the skin. Aloe vera contains a variety of enzymes, such as catalase and amylase, which can help break down harmful substances and promote skin metabolism. Aloe vera contains plant sterols, such as β-sitosterol, which has anti-inflammatory and skin barrier repair effects.

[0019] Green tea is rich in catechins, especially epigallocatechin gallate (EGCG), which is the main antioxidant component in green tea. Catechins have powerful antioxidant, anti-inflammatory and anti-cancer effects. Green tea contains a certain amount of caffeine, which can refresh the mind, promote blood circulation, reduce edema, and is especially suitable for use in eye care products. Green tea is rich in amino acids, especially theanine, which has a calming effect on nerves and can relieve stress and anxiety. Green tea is rich in vitamins C, E and K, especially vitamin C, which has antioxidant effects, can promote collagen synthesis and delay skin aging. Green tea contains a variety of minerals, such as potassium, calcium, magnesium, etc., which help maintain the health of the skin. In addition to catechins, green tea also contains other polyphenolic compounds, such as flavonoids and anthocyanins, which have antioxidant, anti-inflammatory and antibacterial effects.

[0020] Glyceryl caprylate is an ester compound generated by esterification of glycerin and caprylic acid (8-carbon fatty acid). It can absorb moisture from the air, maintain the moisture content of the skin, and prevent dryness of the skin; Glyceryl caprylate has better mildness and biodegradability, is less irritating to the skin, and is suitable for sensitive skin.

[0021] Compared with the prior art, the advantages and beneficial effects of the present invention are: The present invention uses benzophenones, salicylates and metal oxides as light-responsive materials, absorbs and reflects ultraviolet rays, and uses aloe vera and green tea extracts as plant extracts to significantly improve the sunscreen performance of the sunscreen lotion; at the same time, under the effects of anti-inflammatory ingredients, antioxidant ingredients, moisturizing ingredients, etc., the prepared sunscreen lotion has good sunscreen, moisturizing, anti-inflammatory and other properties. DETAILED DESCRIPTION

[0022] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0023] The sources of raw materials used in the present invention are as follows: Lauroyl lysine is derived from lauroyl lysine, item number fxy201612151; shea butter is derived from Jiangxi Global Natural Flavors Co., Ltd., item number 738; arginine is derived from Jiangsu Jiujia Biotechnology Co., Ltd., item number 5120; glyceryl caprylate is derived from Shanghai Yuanye Biotechnology Co., Ltd., item number S25951; phenoxyethanol is derived from Shanghai Yuanye Biotechnology Co., Ltd., item number B67323; cinnamyl salicylate is derived from Shanghai Koraman Reagent Co., Ltd., item number 5105; menthol salicylate is derived from Wuhan Qiaofeng Chemical Technology Co., Ltd., item number 254; avobenzone Wuhan Benjamin Pharmaceutical Co., Ltd., item number 125; oxybenzone is derived from Shanghai Yuanye Biotechnology Co., Ltd., item number S30840.

[0024] Example 1 A method for preparing a sunscreen lotion containing a light-responsive material, comprising the following steps; S1: Benzophenone, salicylate and metal oxide were taken in a mass ratio of 1:1:0.4, and stirred at a temperature of 45°C and a speed of 300r / min for 40min; wherein the benzophenone was a mixture of avobenzone and oxybenzone in a mass ratio of 1:1.2; the salicylate was a mixture of cinnamyl salicylate and menthol salicylate in a mass ratio of 1:1.5; and the metal oxide was a mixture of titanium dioxide and zinc oxide in a mass ratio of 1:0.5; S2: Take aloe vera and green tea in a mass ratio of 1:2, add 10 times the weight of ethanol solution thereto, heat the temperature to 80°C, stir and reflux at a rate of 500 r / min for 2 hours, and distill and concentrate to 1 / 3 to obtain a plant extract; S3: 20 g of the photoresponsive material, 3 g of the anti-inflammatory component and 3 g of the plant extract were mixed, and stirred at a rate of 500 r / min for 1 h at a temperature of 55° C.; the anti-inflammatory component was glyceryl caprylate and phenoxyethanol in a mass ratio of 1:1.3; S4: Add 2g of antioxidant ingredient, 4g of moisturizing ingredient, 0.3g of essence and 10g of water to step S3, wherein the antioxidant ingredient is arginine; the moisturizing ingredient is lauroyl lysine, shea butter and glycerol in a mass ratio of 1:0.5:1; continue stirring at a rate of 600r / min for 20min; then ultrasonically treat at a power of 500W for 30min to obtain the sunscreen containing the light-responsive material.

[0025] Example 2 A method for preparing a sunscreen lotion containing a light-responsive material, comprising the following steps; S1: Benzophenone, salicylate and metal oxide were taken in a mass ratio of 1:2:0.8, and stirred at a temperature of 55°C and a speed of 600r / min for 60min; wherein the benzophenone was a mixture of avobenzone and oxybenzone in a mass ratio of 1:1.5; the salicylate was a mixture of cinnamyl salicylate and menthol salicylate in a mass ratio of 1:1.8; and the metal oxide was a mixture of titanium dioxide and zinc oxide in a mass ratio of 1:0.7; S2: Take aloe vera and green tea in a mass ratio of 1:3, add 20 times the weight of ethanol solution thereto, heat the temperature to 90°C, stir and reflux at a rate of 500 r / min for 5 hours, and distill and concentrate to 1 / 3 to obtain a plant extract; S3: 30 g of the photoresponsive material, 5 g of the anti-inflammatory component and 6 g of the plant extract were mixed, and stirred at a rate of 500 r / min for 2 h at a temperature of 65° C.; the anti-inflammatory component was glyceryl caprylate and phenoxyethanol in a mass ratio of 1:1.6; S4: Add 6g of antioxidant ingredient, 7g of moisturizing ingredient, 0.8g of essence and 20g of water to step S3, wherein the antioxidant ingredient is niacinamide; the moisturizing ingredients are lauroyl lysine, shea butter and glycerol in a mass ratio of 1:0.8:1.5; continue stirring at a rate of 500r / min for 30min; then ultrasonically treat at a power of 600W for 50min to obtain the sunscreen containing the light-responsive material.

[0026] Example 3 A method for preparing a sunscreen lotion containing a light-responsive material, comprising the following steps; S1: Benzophenone, salicylate and metal oxide were taken in a mass ratio of 1:1.5:0.8, and stirred at a temperature of 55°C and a speed of 600r / min for 60min; wherein the benzophenone was a mixture of avobenzone and oxybenzone in a mass ratio of 1:1.3; the salicylate was a mixture of cinnamyl salicylate and menthol salicylate in a mass ratio of 1:1.6; and the metal oxide was a mixture of titanium dioxide and zinc oxide in a mass ratio of 1:0.6; S2: Take aloe vera and green tea in a mass ratio of 1:2.5, add 15 times the weight of ethanol solution thereto, heat to 85°C, stir and reflux at a rate of 600 r / min for 3.5 hours, and distill and concentrate to 1 / 3 to obtain a plant extract; S3: 25g of light-responsive material, 4g of anti-inflammatory ingredient and 5g of plant extract were mixed, and stirred at a rate of 600r / min for 1.5h at a temperature of 60°C; the anti-inflammatory ingredient was glyceryl caprylate and phenoxyethanol in a mass ratio of 1:1.5; the antioxidant ingredient was arginine or niacinamide; the moisturizing ingredient was lauroyl lysine, shea butter and glycerol in a mass ratio of 1:0.6:1.3; S4: Add 4 g of antioxidant ingredients, 5 g of moisturizing ingredients, 0.6 g of essence and 15 g of water to step S3, and continue stirring at a rate of 400 r / min for 25 min; then perform ultrasonic treatment at a power of 800 W for 45 min to obtain the sunscreen containing the light-responsive material.

[0027] Comparative Example 1 The difference from Example 1 is that step S1 contains only benzophenones, and the other steps remain unchanged.

[0028] Comparative Example 2 The difference from Example 1 is that step S1 contains only salicylates, and the other steps remain unchanged.

[0029] Comparative Example 3 The difference from Example 1 is that step S1 only contains metal oxides, and other steps remain unchanged.

[0030] Comparative Example 4 The difference from Example 1 is that step S2 is missing, that is, the plant extract is not added, and the other steps remain unchanged.

[0031] Comparative Example 5 The difference from Example 1 is that the anti-inflammatory component in step S3 does not contain phenoxyethanol, and the other steps remain unchanged.

[0032] Performance Testing: The sunscreen lotions obtained in each embodiment and comparative example were tested for sun protection, stability and anti-allergic performance. In the stability test, the sunscreen lotions were packaged in centrifuge tubes, placed in a centrifuge for centrifugation at 35°C, with a speed of 3000 r / min and a centrifugation time of 30 min. Sunscreen performance test: The PFA value and SPF value of the sunscreen lotion were determined according to the sunscreen index test method (human body method) of the "Technical Specification for Safety of Cosmetics" (2015 edition); Anti-allergic test: Healthy mice weighing 18-22g were randomly divided into 8 groups, each with 10 mice, and the back hair of the animals was removed with 1% sodium sulfide, and the area of ​​the depilated skin area was 1.5×1.5cm; The depilated areas on the backs of the 8 groups of animals were topically smeared with the sunscreen lotions prepared in Examples 1-3 and Comparative Examples 1-5, and they were applied continuously for 5 days, and 30 minutes after the last application, 0.95 mg / kg of dextran was injected into the tail vein of each group of mice, and the itching indication was scratching the head with the front paws, scratching the trunk with the hind paws, and biting various parts of the body with the mouth, and the number of itching times of the mice within 30 minutes was recorded, and the itching inhibition rate was calculated according to the following formula: Itching inhibition rate = (itching times of the negative control group - itching times of the sample group) ÷ itching times of the negative control group 100%. The results are as follows: Table 1

[0033] From the above performance test results, it can be seen that the sunscreen lotions containing light-responsive materials prepared in Examples 1-3 have good sunscreen performance, high stability, and are not allergic to the skin. In particular, Example 3 has better comprehensive performance. However, because Comparative Examples 1-5 do not adopt the necessary technical solutions, they are significantly worse than the embodiments in the corresponding performance tests. The above experimental results further prove the importance of the technical solutions defined in the present invention for its technical effects.

[0034] The above is a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A sunscreen lotion containing a light-responsive material, characterized in that: The invention comprises the following components in parts by weight: 20-30 parts of light-responsive materials, 3-5 parts of anti-inflammatory ingredients, 2-6 parts of antioxidant ingredients, 4-7 parts of moisturizing ingredients, 3-6 parts of plant extracts, 0.3-0.8 parts of essences and 10-20 parts of water.

2. The sunscreen lotion containing light-responsive material according to claim 1, characterized in that: The light-responsive material is composed of benzophenone, salicylate and metal oxide in a mass ratio of 1:1-2:0.4-0.

8.

3. The sunscreen lotion containing light-responsive material according to claim 2, characterized in that: The benzophenone is one of avobenzone and oxybenzone or a mixture thereof; the salicylate is one of cinnamyl salicylate and menthol salicylate or a mixture thereof; and the metal oxide is one of titanium dioxide and zinc oxide or a mixture thereof.

4. The sunscreen lotion containing light-responsive material according to claim 3, characterized in that: The benzophenones are a mixture of avobenzone and oxybenzone in a mass ratio of 1:1.2-1.5; the salicylates are a mixture of cinnamyl salicylate and menthol salicylate in a mass ratio of 1:1.5-1.8; and the metal oxides are a mixture of titanium dioxide and zinc oxide in a mass ratio of 1:0.5-0.

7.

5. The sunscreen lotion containing light-responsive material according to claim 1, characterized in that: The plant extract is aloe vera and green tea extract in a mass ratio of 1:2-3.

6. The sunscreen lotion containing light-responsive material according to claim 1, characterized in that: The anti-inflammatory component is glyceryl caprylate and phenoxyethanol in a mass ratio of 1:1.3-1.6; the antioxidant component is arginine or niacinamide.

7. The sunscreen lotion containing light-responsive material according to claim 1, characterized in that: The moisturizing ingredients are lauroyl lysine, shea butter and glycerol in a mass ratio of 1:0.5-0.8:1-1.

5.

8. A method for preparing a sunscreen lotion containing a light-responsive material, characterized in that: The steps include: S1: Preparation of photoresponsive materials; S2: preparing plant extract; S3: Mix 20-30 parts of the photoresponsive material, 3-5 parts of the anti-inflammatory component and 3-6 parts of the plant extract, and stir continuously for 1-2 hours at a temperature of 55-65°C; S4: Add 2-6 parts of antioxidant ingredients, 4-7 parts of moisturizing ingredients, 0.3-0.8 parts of essence and 10-20 parts of water to step S3, continue stirring for 20-30 minutes; then ultrasonically treat for 30-50 minutes to obtain the sunscreen containing the light-responsive material.

9. The method for preparing a sunscreen lotion containing a light-responsive material according to claim 8, characterized in that: The preparation process of the photoresponsive material in step S1 is as follows: benzophenone, salicylate and metal oxide are respectively taken in a mass ratio of 1:1-2:0.4-0.8, and stirred for reaction at a temperature of 45-55°C for 40-60 minutes.

10. The method for preparing a sunscreen lotion containing a light-responsive material according to claim 8, characterized in that: The preparation process of the plant extract in step S2 is as follows: take aloe vera and green tea according to a mass ratio of 1:2-3, add 10-20 times the weight of ethanol solution thereto, heat the temperature to 80-90°C, stir and reflux for 2-5h, distill and concentrate to 1 / 3, and obtain the plant extract.

Images