Itching-relieving and hair-loss-preventing micro-capsule composition containing golden camellia extract and preparation method of itching-relieving and hair-loss-preventing micro-capsule composition

Abstract

The invention discloses an itching-relieving and hair-loss-preventing micro-capsule composition containing a golden camellia extract and a preparation method of the itching-relieving and hair-loss-preventing micro-capsule composition, and relates to the technical field of daily chemical products. The microcapsule mainly comprises a surfactant, palmitoyl tripeptide, ossein amino acid, betaine salicylate, a nano zinc oxide chelate, a plant extract, vegetable oil and a microcapsule component formed by a microcapsule wall material prepared from gelatin and sodium alginate. The plant extract, the plant oil-containing microcapsules, palmitoyl tripeptide, ossein amino acid, betaine salicylic acid, nano-zinc oxide chelate and the like have synergistic interaction, and the plant extract has antioxidant, antibacterial and anti-inflammatory effects and is matched with other components, so that lasting antibacterial effect is enhanced, dandruff can be effectively cleaned and removed, scalp can be repaired, microcirculation of the scalp can be effectively improved, and the scalp care effect can be improved. The scalp itching is reduced, and the alopecia problem is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of daily chemical products, and in particular to an antipruritic and anti-hair loss microcapsule composition containing golden camellia extract and a preparation method thereof Background Art

[0002] The scalp is the soil on which hair lives, and the balance of its ecological environment is the foundation of hair health. Excessive sebum secretion in the hair can easily lead to microbial reproduction, causing micro-inflammation of the hair, which can reduce the protective barrier of the hair and scalp, causing scalp itching, hair loss and other problems. Irrational use of shampoo can also make the hair loss problem more and more serious.

[0003] There are two shortcomings of the anti-itch and anti-hair loss shampoos on the market. First, some shampoos containing a large amount of chemical agents are highly irritating, and the chemical components are easily left on the scalp, causing damage to the scalp, making it difficult to fundamentally solve the problems of itching and hair loss. Second, shampoos containing Chinese herbal medicines, although such shampoos are less irritating, the existing shampoo products containing Chinese herbal medicine extracts have many Chinese herbal medicine added components, and the simple Chinese herbal medicine components are difficult to fully exert their efficacy in a short period of time, and it is difficult to achieve the desired effect. Summary of the invention

[0004] In view of the above problems, the technical problem to be solved by the present invention is to provide an anti-itch and anti-hair loss microcapsule composition containing Camellia chrysantha extract and a preparation method thereof, which solves the problems that chemical preparations cause excessive damage to the scalp and that existing shampoo products with Chinese herbal components are difficult to improve scalp itching and hair loss in a short period of time.

[0005] In order to achieve the above-mentioned object, the technical scheme adopted by the present invention is as follows: an antipruritic and anti-dehydration microcapsule composition containing golden camellia extract comprises the following components:

[0006] a. Surfactant;

[0007] b. Palmitoyl tripeptide, collagen amino acid, betaine salicylate in a mass ratio of 1-3:0.3-0.5:1;

[0008] c. Nano zinc oxide chelate;

[0009] d. Plant extracts;

[0010] e. microcapsules formed by vegetable oil in a mass ratio of 1:0.6-0.8 and microcapsules formed by microcapsule wall materials made of gelatin and sodium alginate;

[0011] Among them, the weight content of a is 15%-20%, the weight content of b is 0.5%-1.5%, the weight content of c is 0.3%-0.5%, the weight content of d is 3%-6%, the weight content of e is 1%-5%, and the balance is water;

[0012] The plant extract is a composite extract of Camellia chrysantha, Sophora flavescens, Platycladus orientalis leaves and Centella asiatica;

[0013] The vegetable oil comprises tea seed oil, olive oil and tea tree essential oil in a weight ratio of 1:0.5-0.8:0.5-0.8.

[0014] Preferably, the surfactant includes 10-15 parts of cocamidopropyl betaine, 4-6 parts of ethylene glycol distearate, 5-8 parts of coconut acid monoethanolamide, 3-6 parts of decyl glucoside, and 2-5 parts of glyceryl stearate.

[0015] Preferably, the preparation method of the plant extract is:

[0016] (1) Drying Camellia chrysantha, Sophora flavescens, Platycladus orientalis leaves and Centella asiatica, grinding them into fine powder, pouring them into an ultrasonic extraction tank, adding 5-6 times of water to soak, adding 0.1-0.5% of cellulase, hemicellulase and pectinase in the feed liquid, adding 0.05% of citric acid in the feed liquid, heating to 40-45° C. constant temperature stirring enzymolysis treatment for 2-3 hours, after inactivating the enzyme, using 200-300W ultrasonic waves for 40-60 minutes, filtering to obtain filter residue and crude extract;

[0017] (2) adding 1-2 times of water to the filter residue, and then adding 0.5% of the composite fermentation strain and 0.1% of urea in the feed liquid, stirring evenly, fermenting at 30° C. for 24-36 hours, inactivating the fermentation after the fermentation is completed, filtering, collecting the supernatant, and obtaining the fermentation liquid;

[0018] (3) After the crude extract and the fermentation liquid are combined, the extract is separated and purified using a macroporous adsorption resin with a 50%-60% ethanol solution as an eluent, and after concentration, a plant extract is obtained;

[0019] Preferably, the weight ratio of Camellia chrysantha, Sophora flavescens, Platycladus orientalis and Centella asiatica is 1:0.5-1:0.5-1:0.5-1.

[0020] Preferably, the weight ratio of the cellulase, hemicellulase and pectinase is 2:1:1.

[0021] Preferably, the composite fermentation bacteria include Candida utilis and Aspergillus niger in a mass ratio of 1:0.3-0.5.

[0022] Preferably, the mass ratio of gelatin to sodium alginate is 1:1-3.

[0023] Preferably, the preparation method of the nano zinc oxide chelate is as follows: chitosan quaternary ammonium salt is dissolved in water to prepare a chitosan quaternary ammonium salt aqueous solution with a concentration of 1%, nano zinc oxide is added to the aqueous solution under stirring conditions, stirred evenly, and spray-dried to obtain the nano zinc oxide chelate.

[0024] Preferably, the preparation method of the microcapsule is:

[0025] (1) uniformly mixing tea seed oil, olive oil and tea tree essential oil to obtain vegetable oil;

[0026] (2) dissolving gelatin in water to prepare a 5% gelatin aqueous solution, adjusting the solution to be weakly acidic, and dissolving sodium alginate in water to prepare a 5% sodium alginate aqueous solution;

[0027] (3) adding the vegetable oil in step (1) to the sodium alginate aqueous solution under stirring at 8000-10000 r / min, and stirring evenly to disperse and suspend the vegetable oil in the gelatin aqueous solution;

[0028] (4) adding a gelatin aqueous solution to the solution in step (3) under stirring conditions of 2000-3000 r / min, stirring evenly, and spray drying to obtain microcapsules;

[0029] A method for preparing an antipruritic and anti-dehydration microcapsule composition containing a golden camellia extract, characterized in that it comprises the following preparation steps:

[0030] (1) Add appropriate amount of water and surfactant into a container, heat to 70°C-75°C, stir until completely dispersed and then cool down;

[0031] (2) When the temperature drops to about 50° C., add microcapsules and nano zinc oxide chelate, and finally add plant extracts, betaine salicylate, palmitoyl tripeptide, and collagen amino acids at room temperature, stir evenly, and obtain a microcapsule combination.

[0032] Compared with the prior art, the present invention has the following beneficial effects:

[0033] The microcapsule composition of the present invention contains plant extracts, plant oil microcapsules, palmitoyl tripeptide, collagen amino acids, betaine salicylic acid and nano zinc oxide chelate. The plant extract is a composite extract containing golden camellia, sophora flavescens, Platycladus orientalis and Centella asiatica, and contains tea polysaccharides, tea polyphenols, flavonoids, saponins, matrine, tannin asiatica and other physiologically active ingredients, and has antioxidant, antibacterial and anti-inflammatory effects, cleans and relieves itching, repairs the scalp, improves the microcirculation of the scalp, can stimulate and care for the hair stem, and promotes hair regeneration; and the plant extract is a composite extract containing ... seed oil, olive oil and tea in the plant oil. The tree essential oils work synergistically with each other to enhance the antibacterial and anti-inflammatory effects, can remove dandruff, moisturize the scalp, make the hair more lubricated, relieve symptoms such as scalp itching, and reduce the generation of dandruff; palmitoyl tripeptide can promote the growth and thickening of hair by stimulating the expression of hair keratin genes, can help reduce hair loss, and can provide the nutrients needed for hair in combination with collagen amino acids to promote healthy hair growth; betaine salicylate can effectively inhibit the growth of Gram-positive and Gram-negative bacteria and molds, effectively kill the fungi that produce dandruff, and accelerate the shedding of the stratum corneum, thereby playing a role in removing dandruff and relieving itching. The nano zinc oxide chelate in the composition of the present invention has an antibacterial effect, a strong broad-spectrum bactericidal effect, and a more lasting antibacterial effect. It synergizes with plant extracts, microcapsules containing vegetable oils, palmitoyl tripeptide, collagen amino acids, betaine salicylic acid, etc. to enhance the anti-dandruff and antipruritic effects;

[0034] Plant extracts are obtained by dissolving plants in water and performing enzymatic hydrolysis to facilitate the dissolution of effective ingredients. The residue is then fermented by a composite bacterial strain, which greatly increases the leaching rate of effective ingredients and broadens the effective ingredients in the extracts.

[0035] Nano zinc oxide chelate is nano zinc oxide modified by adsorbing on the surface through chitosan quaternary ammonium salt chelate, so that it can be effectively dispersed in shampoo. Chitosan quaternary ammonium salt is positively charged and easily adsorbed on the negatively charged hair surface, enhancing the antibacterial effect;

[0036] The vegetable oil is coated by the microcapsule wall material, thus ensuring its dispersion stability in the water composition. The microcapsule wall material contains negatively charged sodium alginate and positively charged gelatin. When the microcapsule comes into contact with the hair, it can be effectively adsorbed on the negatively charged hair surface. Under the external force of the hand, the wall material breaks, and the active ingredients therein effectively act on the scalp. DETAILED DESCRIPTION

[0037] The specific embodiments of the present invention are further described below in conjunction with the examples. In these examples, unless otherwise specified, all concentrations are weight percentages.

[0038] Example 1

[0039] An antipruritic and anti-dehydration microcapsule composition containing golden camellia extract, comprising the following components:

[0040] a. Surfactant;

[0041] b. Palmitoyl tripeptide, collagen amino acid, and betaine salicylate in a mass ratio of 1:0.3:1;

[0042] c. Nano zinc oxide chelate;

[0043] d. Plant extracts;

[0044] e. microcapsules formed by vegetable oil in a mass ratio of 1:0.6 and microcapsule wall materials made of gelatin and sodium alginate;

[0045] Among them, the weight content of a is 15%, the weight content of b is 0.5%, the weight content of c is 0.3%, the weight content of d is 3%, the weight content of e is 1%, and the balance is water;

[0046] The plant extract is a composite extract of Camellia chrysantha, Sophora flavescens, Platycladus orientalis leaves and Centella asiatica;

[0047] The vegetable oil includes tea seed oil, olive oil and tea tree essential oil in a weight ratio of 1:0.5:0.5;

[0048] The surfactant includes 10 parts of cocamidopropyl betaine, 4 parts of ethylene glycol distearate, 5 parts of coconut acid monoethanolamide, 3 parts of decyl glucoside and 2 parts of glyceryl stearate.

[0049] The mass ratio of gelatin to sodium alginate is 1:1;

[0050] Preferably, the preparation method of the plant extract is:

[0051] (1) Drying and grinding Camellia chrysantha, Sophora flavescens, Platycladus orientalis and Centella asiatica in a weight ratio of 1:0.5:0.5:0.5 into fine powder, pouring into an ultrasonic extraction tank, adding 6 times of water to soak, adding 0.1% of cellulase, hemicellulase and pectinase in a feed liquid, wherein the weight ratio of the cellulase, hemicellulase and pectinase is 2:1:1, adding 0.05% of citric acid in a feed liquid, heating to 40-45° C. constant temperature stirring enzymolysis treatment for 2-3 hours, after inactivating the enzyme, using 200-300W ultrasonic wave treatment for 40-60 minutes, filtering to obtain a filter residue and a crude extract;

[0052] (2) adding 1 times of water to the filter residue, and then adding 0.5% of the composite fermentation strain and 0.1% of urea in the feed liquid, wherein the composite fermentation strain includes Candida utilis and Aspergillus niger in a mass ratio of 1:0.3, stirring evenly, fermenting at 30° C. for 24-36 hours, inactivating the fermentation after the fermentation is completed, filtering, and collecting the supernatant;

[0053] (3) After the crude extract and the fermentation liquid are combined, the extract is separated and purified using a macroporous adsorption resin with a 50%-60% ethanol solution as an eluent, and after concentration, a plant extract is obtained;

[0054] The preparation method of nano zinc oxide chelate is as follows: chitosan quaternary ammonium salt is dissolved in water to prepare a chitosan quaternary ammonium salt aqueous solution with a concentration of 1%, nano zinc oxide is added to the aqueous solution under stirring conditions, and after being stirred and dispersed uniformly at a speed of 10000r / min, spray drying is performed to obtain nano zinc oxide chelate; the mass ratio of nano zinc oxide to chitosan quaternary ammonium salt is 1:0.5, and the particle size of nano zinc oxide is 50-100nm;

[0055] The preparation method of microcapsules is:

[0056] (1) uniformly mixing tea seed oil, olive oil and tea tree essential oil to obtain vegetable oil;

[0057] (2) dissolving gelatin in water to prepare a 5% gelatin aqueous solution, adjusting the pH value of the solution to 4.5 to be weak, and dissolving sodium alginate in water to prepare a 5% sodium alginate aqueous solution;

[0058] (3) adding the vegetable oil prepared in step (1) to the sodium alginate aqueous solution under stirring at 8000 r / min, and stirring evenly to disperse and suspend the vegetable oil in the gelatin aqueous solution;

[0059] (4) adding a gelatin aqueous solution to the solution in step (3) under stirring at 2000 r / min, stirring evenly, and spray drying to obtain microcapsules;

[0060] A method for preparing an antipruritic and anti-dehydration microcapsule composition containing a golden camellia extract comprises the following preparation steps:

[0061] (1) Add appropriate amount of water and surfactant into a container, heat to 70°C-75°C, stir until completely dispersed and then cool down;

[0062] (2) When the temperature drops to about 50° C., add microcapsules and nano zinc oxide chelate, and finally add plant extracts, betaine salicylate, palmitoyl tripeptide, and collagen amino acids at room temperature, stir evenly, and obtain a microcapsule combination.

[0063] Example 2

[0064] An antipruritic and anti-dehydration microcapsule composition containing golden camellia extract, comprising the following components:

[0065] a. Surfactant;

[0066] b. Palmitoyl tripeptide, collagen amino acid, and betaine salicylate in a mass ratio of 1:0.5:1;

[0067] c. Nano zinc oxide chelate;

[0068] d. Plant extracts;

[0069] e. microcapsules formed by vegetable oil and microcapsule wall materials made of gelatin and sodium alginate in a mass ratio of 1:0.8;

[0070] Among them, the weight content of a is 15%, the weight content of b is 0.5%, the weight content of c is 0.3%, the weight content of d is 3%, the weight content of e is 1%, and the balance is water;

[0071] The plant extract is a composite extract of Camellia chrysantha, Sophora flavescens, Platycladus orientalis leaves and Centella asiatica;

[0072] The vegetable oil includes tea seed oil, olive oil and tea tree essential oil in a weight ratio of 1:0.5:0.8;

[0073] The mass ratio of gelatin to sodium alginate is 1:3;

[0074] The surfactant includes 10 parts of cocamidopropyl betaine, 4 parts of ethylene glycol distearate, 5 parts of coconut acid monoethanolamide, 3 parts of decyl glucoside and 2 parts of glyceryl stearate.

[0075] The preparation method of the plant extract is:

[0076] (1) Drying and grinding Camellia chrysantha, Sophora flavescens, Platycladus orientalis leaves and Centella asiatica in a weight ratio of 1:0.5:0.5:0.5 into fine powder, pouring into an ultrasonic extraction tank, adding 5 times of water for soaking, adding 0.1% of cellulase, hemicellulase and pectinase in a feed liquid ratio of 2:1:1, adding 0.05% of citric acid in a feed liquid, heating to 40-45° C. constant temperature stirring enzymolysis treatment for 2-3 hours, after inactivating the enzyme, using 200-300W ultrasonic waves for 40-60 minutes, filtering to obtain a filter residue and a crude extract;

[0077] (2) adding 1 times of water to the filter residue, and then adding 0.5% of the composite fermentation strain and 0.1% of urea in the feed liquid, wherein the composite fermentation strain includes Candida utilis and Aspergillus niger in a mass ratio of 1:0.5, stirring evenly, fermenting at 30° C. for 24-36 hours, inactivating the fermentation after the fermentation is completed, filtering, collecting the supernatant, and obtaining a fermentation liquid;

[0078] (3) After the crude extract and the fermentation liquid are combined, the extract is separated and purified using a macroporous adsorption resin with a 50%-60% ethanol solution as an eluent, and after concentration, a plant extract is obtained;

[0079] The preparation method of the nano zinc oxide chelate comprises the following steps: dissolving chitosan quaternary ammonium salt in water to prepare a chitosan quaternary ammonium salt aqueous solution with a concentration of 1%, adding nano zinc oxide into the aqueous solution under stirring conditions, stirring and dispersing the solution uniformly at a speed of 10000 r / min, and spray drying to obtain the nano zinc oxide chelate; the mass ratio of nano zinc oxide to chitosan quaternary ammonium salt is 1:0.5, and the particle size of the nano zinc oxide is 50-100 nm;

[0080] Preferably, the preparation method of the microcapsule is:

[0081] (1) uniformly mixing tea seed oil, olive oil and tea tree essential oil to obtain vegetable oil;

[0082] (2) dissolving gelatin in water to prepare a 5% gelatin aqueous solution, adjusting the pH value of the solution to below the isoelectric point, and dissolving sodium alginate in water to prepare a 5% sodium alginate aqueous solution;

[0083] (3) adding the vegetable oil prepared in step (1) to the sodium alginate aqueous solution under stirring at 10,000 r / min, and stirring evenly to disperse and suspend the vegetable oil in the gelatin aqueous solution;

[0084] (4) adding a gelatin aqueous solution to the solution in step (3) under stirring at 3000 r / min, stirring evenly, and spray drying to obtain microcapsules;

[0085] The preparation method of the microcapsule composition is the same as that of Example 1.

[0086] Example 3

[0087] An antipruritic and anti-dehydration microcapsule composition containing golden camellia extract, comprising the following components:

[0088] a. Surfactant;

[0089] b. Palmitoyl tripeptide, collagen amino acid, and betaine salicylate in a mass ratio of 3:0.5:1;

[0090] c. Nano zinc oxide chelate;

[0091] d. Plant extracts;

[0092] e. microcapsules formed by vegetable oil in a mass ratio of 1:0.8 and microcapsule wall materials made of gelatin and sodium alginate;

[0093] Among them, the weight content of a is 20%, the weight content of b is 1.5%, the weight content of c is 0.5%, the weight content of d is 6%, the weight content of e is 5%, and the balance is water;

[0094] The plant extract is a composite extract of Camellia chrysantha, Sophora flavescens, Platycladus orientalis leaves and Centella asiatica;

[0095] The vegetable oil includes camellia oil, olive oil and tea tree essential oil in a weight ratio of 1:0.8:0.8;

[0096] The mass ratio of gelatin to sodium alginate is 1:3;

[0097] The surfactant includes 15 parts of cocamidopropyl betaine, 6 parts of ethylene glycol distearate, 8 parts of coconut acid monoethanolamide, 6 parts of decyl glucoside and 5 parts of glyceryl stearate.

[0098] The preparation method of the plant extract is:

[0099] (1) Drying and grinding Camellia chrysantha, Sophora flavescens, Platycladus orientalis leaves and Centella asiatica in a weight ratio of 1:1:1:1 into fine powder, pouring into an ultrasonic extraction tank, adding 5-6 times of water for soaking, adding 0.5% of cellulase, hemicellulase and pectinase in a feed liquid ratio of 2:1:1, adding 0.05% of citric acid in a feed liquid, heating to 40-45° C. constant temperature stirring enzymolysis treatment for 2-3 hours, after inactivating the enzyme, using 200-300W ultrasonic wave treatment for 40-60 minutes, filtering to obtain a filter residue and a crude extract;

[0100] (2) adding 2 times of water to the filter residue, and then adding 0.5% of the composite fermentation strain and 0.1% of urea in the feed liquid, wherein the composite fermentation strain includes Candida utilis and Aspergillus niger in a mass ratio of 1:0.5, stirring evenly, fermenting at 30° C. for 24-36 hours, performing inactivation treatment after fermentation, filtering, collecting the supernatant, and obtaining a fermentation liquid;

[0101] (3) After the crude extract and the fermentation liquid are combined, the extract is separated and purified using a macroporous adsorption resin with a 50%-60% ethanol solution as an eluent, and after concentration, a plant extract is obtained;

[0102] The preparation methods of the nano zinc oxide chelate, the microcapsule and the microcapsule composition are the same as those in Example 1.

[0103] Comparative Example 1

[0104] The components of the microcapsule composition differ from those of Example 1 only in that the composition does not contain plant extracts, and the other components and contents remain unchanged. The preparation methods of the nano zinc oxide chelate, the preparation methods of the microcapsules, and the preparation methods of the microcapsule composition are similar to those of Example 1.

[0105] Comparative Example 2

[0106] The components of the microcapsule composition differ from those of Example 1 only in that the microcapsule is not included, and the other components and contents remain unchanged. The preparation methods of the nano zinc oxide chelate and the microcapsule composition are referred to Example 1.

[0107] Comparative Example 3

[0108] The components of the microcapsule composition differ from those of Example 1 only in that betaine salicylate is not contained, and other components and contents remain unchanged. The preparation methods of the nano zinc oxide chelate, the preparation methods of the microcapsules and the preparation methods of the microcapsule composition are similar to those of Example 1.

[0109] Comparative Example 4

[0110] The components of the microcapsule composition differ from those of Example 1 only in that it does not contain palmitoyl tripeptide and collagen amino acids, and the other components and their contents remain unchanged. The preparation methods of the nano zinc oxide chelate, the preparation methods of the microcapsules and the preparation methods of the microcapsule composition are similar to those of Example 1.

[0111] Comparative Example 5

[0112] The components of the microcapsule composition differ from those of Example 1 only in that the nano zinc oxide chelate is not contained, and the other components and contents remain unchanged. The preparation methods of the nano zinc oxide chelate, the preparation methods of the microcapsules and the preparation methods of the microcapsule composition are similar to those of Example 1.

[0113] Effects of using shampoo

[0114] The experiment selected 160 volunteers aged between 25 and 40 with itching and hair loss problems, regardless of gender. The patients were randomly divided into 8 groups, with 20 people in each group. Among them, experimental group 1 used the shampoo of Example 1, experimental group 2 used the shampoo of Example 2, experimental group 3 used the shampoo of Example 3, experimental group 4 used the shampoo of Comparative Example 1, experimental group 5 used the shampoo of Comparative Example 2, experimental group 6 used the shampoo of Comparative Example 3, experimental group 7 used the shampoo of Comparative Example 4, and experimental group 8 used the shampoo of Comparative Example 5. The test lasted for 8 weeks. The testers washed their hair once every 2 days, 10 ml each time. The comprehensive effects of the hair and scalp were scored, and the improvement of the user's hair loss was recorded. The results are shown in Tables 1 and 2.

[0115] Table 1 Comprehensive use effect

[0116]

[0117]

[0118] Note: The product performance is divided into 5 levels: 5: good; 4: better; 3: average; 2: poor; 1: poor.

[0119] Table 2 Anti-shedding effect

[0120] Example Number of cases Significant effect efficient invalid Example 1 20 15 5 0 Example 2 20 17 3 0 Example 3 20 16 4 0 Comparative Example 1 20 1 11 8 Comparative Example 2 20 2 5 13 Comparative Example 3 20 3 8 9 Comparative Example 4 20 3 7 10 Comparative Example 5 20 2 6 12

[0121] The criteria for judging the effect are as follows: markedly effective: the number of hairs lost in the combing test decreased by >50% compared with before treatment, and new hair growth was more; effective: the number of hairs lost in the combing test decreased by ≤50% compared with before treatment, and new hair growth was less; ineffective: the number of hairs lost in the combing test decreased by ≤20% compared with before treatment, and there was no change or worsening in all aspects compared with before treatment.

[0122] As shown in Table 1 and Table 2, the microcapsule composition of the present invention can improve the scalp environment and has a significant effect in relieving itching and preventing hair loss. The present invention utilizes the combination of plant extracts, vegetable oils, palmitoyl tripeptide, collagen amino acids, betaine salicylate and nano zinc oxide chelate in the components, and the components work together to greatly improve the scalp itching and hair loss of patients. Compared with Comparative Examples 1-5, individual raw material components are deleted, and the improvement effects of scalp itching, hair loss, etc. will be reduced.

[0123] The Camellia chrysantha extract of the present invention contains tea polysaccharides, tea polyphenols, flavonoids and other physiologically active ingredients, has strong antioxidant activity and anti-inflammatory effects, can effectively remove free radicals, inhibit inflammation, and inhibit the stimulation of micro-inflammation on hair follicle cells; the Sophora flavescens extract contains alkaloids and flavonoids, has antioxidant, antibacterial and anti-inflammatory effects, Sophora flavescens contains rich saponin components, has a strong cleaning effect, can remove oil and dirt on hair, and at the same time, the matrine component in Sophora flavescens has the effect of regulating sebum secretion, reducing the problems of greasy hair and dandruff; the Platycladus orientalis leaf extract contains flavonoids and tannins and other components, has antibacterial and antifungal effects, can stimulate and care for hair stems, can promote hair regeneration, and enhance the metabolic function of hair follicles; the asiatica glycoside in the Centella asiatica extract can promote collagen synthesis and new blood vessel formation, can Repair the scalp, improve the microcirculation of the scalp, and promote hair growth. The triterpenoid saponin compounds in the Centella asiatica extract have strong moisturizing properties, avoid dry scalp, and reduce the generation of dandruff; the tea seed oil, olive oil, and tea tree essential oil in the plant oils work synergistically with each other, have certain antibacterial and anti-inflammatory effects, can remove dandruff, moisturize the scalp, make the hair more lubricated, relieve symptoms such as scalp itching, and reduce the generation of dandruff; palmitoyl tripeptide can promote the growth and thickening of hair by stimulating the expression of hair keratin genes, can help reduce hair loss, and can provide the nutrients required by hair with collagen amino acids to promote healthy hair growth; betaine salicylate can effectively inhibit the growth of Gram-positive, Gram-negative bacteria and molds, effectively kill fungi that produce dandruff, and accelerate the shedding of the stratum corneum, thereby playing the role of removing dandruff and relieving itching. The nano zinc oxide chelate and antibacterial particles in the composition of the present invention have the effects of dust removal, antibacterial, sterilization, and fatigue elimination. Nano silver particles with strong spectrum bactericidal effect have a long-lasting antibacterial effect, can kill bacteria, viruses, fungi and other microorganisms, and can effectively control stubborn and resistant antibacterial strains of bacteria. A very small amount of silver can kill a large number of pathogenic organisms. Therefore, nano zinc oxide chelate is added to shampoo, which has antibacterial effect, and synergizes with plant extracts, microcapsules containing vegetable oils, palmitoyl tripeptide, collagen amino acids, betaine salicylic acid, etc., to achieve long-lasting antibacterial and enhanced anti-dandruff and antipruritic effects.

[0124] The above description is a detailed description of the preferred feasible embodiments of the present invention, but the embodiments are not intended to limit the scope of the patent application of the present invention. All equivalent changes or modified changes completed under the technical spirit suggested by the present invention should belong to the patents covered by the present invention.

Claims

1. An antipruritic and anti-dehydration microcapsule composition containing golden camellia extract, characterized in that: Contains the following ingredients: a. Surfactant; b. Palmitoyl tripeptide, collagen amino acid, betaine salicylate in a mass ratio of 1-3:0.3-0.5:1; c. Nano zinc oxide chelate; d. Plant extracts; e. Microcapsules formed of vegetable oil, microcapsule wall material made of gelatin and sodium alginate in a mass ratio of 1:0.6-0.8; Among them, the weight content of a is 15%-20%, the weight content of b is 0.5%-1.5%, the weight content of c is 0.3%-0.5%, the weight content of d is 3%-6%, the weight content of e is 1%-5%, and the balance is water; The plant extract is a composite extract of Camellia chrysantha, Sophora flavescens, Platycladus orientalis leaves and Centella asiatica; The vegetable oil comprises tea seed oil, olive oil and tea tree essential oil in a weight ratio of 1:0.5-0.8:0.5-0.

8.

2. The antipruritic and anti-dehydration microcapsule composition containing golden camellia extract according to claim 1, characterized in that: The surfactant comprises 10-15 parts of cocamidopropyl betaine, 4-6 parts of ethylene glycol distearate, 5-8 parts of coconut acid monoethanolamide, 3-6 parts of decyl glucoside and 2-5 parts of glyceryl stearate.

3. The antipruritic and anti-dehydration microcapsule composition containing golden camellia extract according to claim 1, characterized in that: The preparation method of the plant extract is: (1) Drying Camellia chrysantha, Sophora flavescens, Platycladus orientalis leaves and Centella asiatica, grinding them into fine powder, pouring them into an ultrasonic extraction tank, adding 5-6 times of water to soak, adding 0.1-0.5% of cellulase, hemicellulase and pectinase in the feed liquid, adding 0.05% of citric acid in the feed liquid, heating to 40-45° C. constant temperature stirring enzymolysis treatment for 2-3 hours, after inactivating the enzyme, using 200-300W ultrasonic waves for 40-60 minutes, filtering to obtain filter residue and crude extract; (2) adding 1-2 times of water to the filter residue, and then adding 0.5% of the composite fermentation strain and 0.1% of urea in the feed liquid, stirring evenly, fermenting at 30° C. for 24-36 hours, inactivating the fermentation after the fermentation is completed, filtering, collecting the supernatant, and obtaining the fermentation liquid; (3) After the crude extract and the fermentation liquid are combined, the extract is separated and purified using a macroporous adsorption resin with a 50%-60% ethanol solution as an eluent, and after concentration, a plant extract is obtained.

4. The antipruritic and anti-dehydration microcapsule composition containing golden camellia extract according to claim 3, characterized in that: The weight ratio of the camellia chrysantha, sophora flavescens, cypress leaves and Centella asiatica is 1:0.5-1:0.5-1:0.5-1.

5. The antipruritic and anti-dehydration microcapsule composition containing golden camellia extract according to claim 3, characterized in that: The weight ratio of the cellulase, hemicellulase and pectinase is 2:1:

1.

6. The antipruritic and anti-dehydration microcapsule composition containing golden camellia extract according to claim 1, characterized in that: The composite fermentation strains include Candida utilis and Aspergillus niger in a mass ratio of 1:0.3-0.

5.

7. The antipruritic and anti-dehydration microcapsule composition containing golden camellia extract according to claim 1, characterized in that: The mass ratio of the gelatin to sodium alginate is 1:1-3.

8. The antipruritic and anti-dehydration microcapsule composition containing golden camellia extract according to claim 1, characterized in that: The preparation method of the nano zinc oxide chelate is as follows: chitosan quaternary ammonium salt is dissolved in water to prepare a chitosan quaternary ammonium salt aqueous solution with a concentration of 1%, nano zinc oxide is added to the aqueous solution under stirring conditions, stirred evenly, and spray-dried to obtain the nano zinc oxide chelate.

9. The antipruritic and anti-dehydration microcapsule composition containing golden camellia extract according to claim 1, characterized in that: The preparation method of the microcapsule is: (1) uniformly mixing tea seed oil, olive oil and tea tree essential oil to obtain vegetable oil; (2) dissolving gelatin in water to prepare a 5% gelatin aqueous solution, adjusting the solution to be weakly acidic, and dissolving sodium alginate in water to prepare a 5% sodium alginate aqueous solution; (3) adding the vegetable oil in step (1) to the sodium alginate aqueous solution under stirring at 8000-10000 r / min, and stirring evenly to disperse and suspend the vegetable oil in the gelatin aqueous solution; (4) Adding gelatin aqueous solution to the solution in step (3) under stirring at 2000-3000 r / min, stirring evenly, and spray drying to obtain microcapsules.

10. A method for preparing an antipruritic and anti-dehydration microcapsule composition containing a Camellia chrysantha extract according to any one of claims 1 to 9, characterized in that: The method comprises the following preparation steps: (1) Add appropriate amount of water and surfactant into a container, heat to 70°C-75°C, stir until completely dispersed and then cool down; (2) When the temperature drops to about 50° C., add microcapsules and nano zinc oxide chelate, and finally add plant extracts, betaine salicylate, palmitoyl tripeptide, and collagen amino acids at room temperature, stir evenly, and obtain a microcapsule composition.

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