Self-service sampling device for tumor marker detection

By designing a self-service sampling device containing multiple disposable mechanisms, the problem of unstable operation and inability to receive urine in one go in the sampling process in the prior art is solved, stable, accurate and efficient urine sampling is achieved, and the efficiency of tumor marker detection is improved.

CN119908763APending Publication Date: 2025-05-02NANFANG HOSPITAL OF SOUTHERN MEDICAL UNIV
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Patent Information

Application Number
CN202510412870.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-04-03
Publication Date
2025-05-02

AI Technical Summary

Technical Problem

The existing tumor marker detection device is unstable during the sampling process, which can easily lead to urine sputtering and cannot take over the entire urination volume at one time, resulting in cross-contamination and inconvenience in operation.

Method used

A self-service sampling device including a disposable receiving mechanism, a disposable pre-storage mechanism, a disposable puncture mechanism, a disposable tube clamping mechanism and a vacuum liquid extraction storage mechanism are designed. The device imitates the shape of the chamber pot mouth by connecting the urine cover bucket and extending the neck, temporarily stores urine with a urine bag, and achieves stable and efficient urine sampling through a vacuum liquid extraction storage mechanism.

Benefits of technology

The device can perform self-sampling after one urination, avoid operational inconvenience caused by mid-sampling, ensure stable urine acceptance and accuracy, reduce the risk of urine sputtering, and improve the accuracy and efficiency of detection.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to the technical field of tumor marker detection, and discloses a self-service sampling device for tumor marker detection, which comprises a disposable receiving mechanism, a disposable pre-storage mechanism is arranged at the bottom of the disposable receiving mechanism, a disposable puncturing mechanism is arranged at the bottom of the disposable pre-storage mechanism, and the disposable pre-storage mechanism and the disposable puncturing mechanism are arranged on the bottom of the disposable receiving mechanism. A disposable pipe clamping mechanism is arranged at the bottom of the disposable puncturing mechanism, and a vacuum liquid pumping and storing mechanism is installed at the bottom of the disposable pipe clamping mechanism. According to the self-service sampling device for tumor marker detection, through the arrangement of the disposable receiving mechanism, the disposable pre-storage mechanism, the disposable puncturing mechanism, the disposable pipe clamping mechanism and the vacuum liquid pumping storage mechanism, the urine volume of one time can be temporarily stored through a urine bag during use, and the urethra outlet is covered with a urine receiving cover hopper; therefore, urine is prevented from being received during urination, stable receiving is guaranteed, and urine splashing is avoided.
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Description

Technical Field

[0001] The present invention relates to the technical field of tumor marker detection, and in particular to a self-service sampling device for tumor marker detection. Background Art

[0002] Tumor markers, also known as tumor markers, refer to substances that characteristically exist in malignant tumor cells, or are abnormally produced by malignant tumor cells, or are produced by the host's response to tumor stimulation, and can reflect the occurrence and development of tumors and monitor the tumor's response to treatment. Tumor markers exist in the tissues, body fluids and excretions of tumor patients and can be detected by immunological, biological and chemical methods. In addition to urinary tract tumor biomarkers, urine also contains tumor biomarkers of various other organs. This is because the kidney is an organ that produces urine and has a rich blood supply. It is an important organ for excreting metabolic waste from the human body. Markers with very low concentrations in urine can accumulate through the high rate of renal turnover and concentration functions, leading to increased concentrations. Non-invasive urine biomarkers are beneficial for cancer patients in detection, treatment decisions and prognosis.

[0003] Before testing for tumor markers in urine, patients are required to take urine samples on their own. However, most general sampling devices use a small urine cup to collect urine, and then introduce it into a test tube for testing. However, since the volume of the urine cup is too small to collect the total amount of urination at one time, in order to avoid cross contamination, the urine needs to be collected in the middle of urination when the urine cup is collected. This makes the operation very inconvenient and prone to unstable operation, resulting in urine splashing. Summary of the invention

[0004] In view of the deficiencies of the prior art, the present invention provides a self-service sampling device for tumor marker detection, which solves the problems mentioned in the above background.

[0005] The present invention provides the following technical solution: a self-service sampling device for tumor marker detection, comprising: a disposable receiving mechanism, a disposable pre-storage mechanism is arranged at the bottom of the disposable receiving mechanism, a disposable puncture mechanism is arranged at the bottom of the disposable pre-storage mechanism, a disposable tube clamping mechanism is arranged at the bottom of the disposable puncture mechanism, and a vacuum liquid extraction storage mechanism is installed at the bottom of the disposable tube clamping mechanism.

[0006] Preferably, the disposable receiving mechanism includes a urine collecting bucket, an extension neck, a holding piece and a holding hole, the extension neck is integrally arranged at the bottom of the urine collecting bucket, and the materials of the urine collecting bucket and the extension neck are both light-transmitting materials, the holding piece is integrally arranged on the surface of the urine collecting bucket, and the holding hole is opened through the surface of the urine collecting bucket.

[0007] Preferably, the disposable receiving mechanism also includes a buffer ring, an inflation cavity and an anti-backflow valve, the buffer ring is fixedly connected to the surface of the urine collecting bucket, and the buffer ring corresponds to the edge of the urine collecting bucket, the inflation cavity is opened inside the buffer ring, and the inside of the inflation cavity is filled with air, the anti-backflow valve is integrally arranged on the surface of the buffer ring, and the anti-backflow valve is located inside the urine collecting bucket, and the anti-backflow valve faces the side of the urine collecting bucket close to the extension neck.

[0008] Preferably, the disposable receiving mechanism further comprises an inner frame tube, a splash-proof sheet and a seepage hole, wherein the inner frame tube is fixedly connected to the inner wall of the extension neck away from the end of the urine collecting bucket, the splash-proof sheet is fixedly connected to the inner wall of the inner frame tube, and the seepage hole is opened through the surface of the splash-proof sheet.

[0009] Preferably, the disposable pre-storage mechanism includes a lower connecting hose, a one-way valve, a urine bag, a connecting plate, a tube clamp and a tube pulling groove, the lower connecting hose is fixedly connected to the bottom end of the extension neck, the one-way valve is fixedly installed in the middle of the lower connecting hose, and the one-way valve is conductive in the direction away from the extension neck, the urine bag is fixedly connected to the bottom end of the lower connecting hose, there are two connecting plates, and the two connecting plates are respectively fixedly connected to the surfaces on both sides of the urine bag, the tube clamp is integrally arranged on the surface of the connecting plate, and the tube pulling groove is embedded in the middle of the tube clamp.

[0010] Preferably, the disposable pre-storage mechanism also includes a lower three-way hose, a sampling hose, an emptying hose and an emptying hard pipe head, the lower three-way hose is fixedly connected to the bottom end of the urine bag, the main output end of the lower three-way hose and the branch output end of the lower three-way hose are both provided with switch valves, the sampling hose is fixedly connected to the main output end of the lower three-way hose through the switch valve, the emptying hose is fixedly connected to the branch output end of the lower three-way hose through another switch valve, and the emptying hard pipe head is fixedly connected to the output end of the emptying hose.

[0011] Preferably, the switch valve includes a connecting valve body, a valve shaft, a valve ball, a sealing ring and a twist piece. The number of the connecting valve bodies is two, and the two connecting valve bodies are respectively fixedly connected between the main output end of the lower three-way hose and the sampling hose and between the branch output end of the lower three-way hose and the emptying hose. The valve shaft is rotatably connected to the inside of the connecting valve body, the valve ball is fixedly connected to one end of the valve shaft, the sealing ring is fixedly connected to the inner wall of the connecting valve body, and the surface of the sealing ring is slidably connected to the surface of the valve shaft, and the twist piece is fixedly connected to one end of the valve shaft.

[0012] Preferably, the disposable puncturing mechanism comprises a hydraulic pressure discharge cover, an upper pressing plate, a rubber plug puncturing needle, a rubber needle cover, a sliding cylinder, an anti-slip head, a sliding guide ridge and a reset spring; the hydraulic pressure discharge cover is fixedly connected to the output end of the sampling hose, the upper pressing plate is integrally arranged on the surface of the hydraulic pressure discharge cover, the rubber plug puncturing needle is fixedly inserted in the interior of the hydraulic pressure discharge cover, the rubber needle cover is fixedly sleeved on one end of the rubber plug puncturing needle, the sliding cylinder is integrally arranged at the bottom of the hydraulic pressure discharge cover, the anti-slip head and the sliding guide ridge are both integrally arranged on the surface of the sliding cylinder, and the reset spring is movably sleeved on the surface of the sliding cylinder.

[0013] Preferably, the disposable tube clamping mechanism includes a connecting tube, a lower pressing plate and an anti-deflection slide groove, the connecting tube is slidably connected to the surface of the slide tube, the lower pressing plate is integrally arranged on the surface of the connecting tube, the return spring is located between the lower pressing plate and the upper pressing plate, the anti-deflection slide groove is opened on the inner wall of the connecting tube, and the inner wall of the anti-deflection slide groove is slidably connected to the surface of the guide slide ridge, and the inner wall of the connecting tube is provided with an internal thread.

[0014] Preferably, the vacuum liquid extraction and storage mechanism includes a sealing shell, a limiting ring, a vacuum test tube and a rubber sealing plug. The surface of the sealing shell is provided with an external thread, and the sealing shell is threadedly connected to the connecting tube through the external thread and the internal thread. The limiting ring is integrally arranged on the surface of the sealing shell, the vacuum test tube is fixedly connected to the bottom of the sealing shell, and the rubber sealing plug is fixedly connected between the sealing shell and the vacuum test tube.

[0015] Compared with the prior art, the present invention has the following beneficial effects: The self-service sampling device for tumor marker detection can temporarily store a urine volume through a urine bag when in use by means of a disposable receiving mechanism, a disposable pre-storage mechanism, a disposable puncturing mechanism, a disposable tube clamping mechanism and a vacuum liquid extraction and storage mechanism, and cover the urethral outlet through a urine receiving cover, thereby avoiding receiving urine in the middle of urination, ensuring stable receiving and avoiding urine splashing.

[0016] The self-service sampling device for tumor marker detection can imitate the shape of the mouth of a chamber pot through the urine collecting bucket and the extended neck by means of the urine collecting bucket, the extended neck, the holding piece, the holding hole, the buffer ring, the inflation cavity, the anti-reflux valve, the internal frame tube, the anti-splash sheet and the seepage hole when in use, so as to ensure that the urethral outlet can be wrapped to suit the different physiological structures of men and women and ensure accuracy, and at the same time, splashing can be avoided by the anti-splash sheet, and the anti-reflux valve can be used to prevent the residual urine on the inner wall of the urine collecting bucket from flowing back when the urine collecting bucket is tilted.

[0017] The self-service sampling device for tumor marker detection can temporarily store a urine volume when in use through the lower connecting hose, one-way valve, urine bag, connecting plate, tube clamp, tube pulling groove, lower three-way hose, sampling hose, emptying hose, emptying hard tube head, connecting valve body, valve shaft, valve ball, sealing ring and twist piece, so as to ensure that the patient can perform self-service sampling after urination once, avoiding the operational inconvenience caused by sampling in the middle.

[0018] The self-service sampling device for tumor marker detection can penetrate the rubber sealing plug through the rubber plug piercing needle during sampling, thereby connecting the vacuum test tube with the urine bag, and realizing sampling, by means of the hydraulic pressure discharge cover, the upper pressing sheet, the rubber plug piercing needle, the rubber needle cover, the sliding cylinder, the anti-dropping head, the sliding guide ridge and the reset spring.

[0019] The self-service sampling device for tumor marker detection can fix the vacuum test tube when in use by means of the connecting tube, the lower pressing piece and the anti-deviation slide groove, and can cooperate with the force of the lower pressing piece during sampling to ensure the insertion of the rubber stopper piercing needle.

[0020] The self-service sampling device for tumor marker detection, through the provided sealing shell, limiting ring, vacuum test tube and rubber sealing plug, can suck the urine in the urine bag into the vacuum test tube through the negative pressure formed by the vacuum inside the vacuum test tube during sampling, and after sampling, the rubber sealing plug is used to seal to prevent the urine from easily shaking and flowing out. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 It is a schematic diagram of the structure of the present invention; Figure 2 It is a structural schematic diagram of the one-time receiving mechanism of the present invention; Figure 3 It is a cross-sectional view of the disposable receiving mechanism of the present invention; Figure 4 This is a schematic diagram of the structure of the lower three-way hose of the present invention; Figure 5 This is a cross-sectional view of the internal structure of the connecting valve body of the present invention; Figure 6 It is a cross-sectional view of the disposable puncturing mechanism and the disposable tube clamping mechanism of the present invention; Figure 7 This is a schematic diagram of the explosion structure at the connecting tube position of the present invention; Figure 8 It is a cross-sectional view of the vacuum liquid extraction and storage mechanism of the present invention; Fig. 9 It is a schematic diagram of the structure of the pipe clamp of the present invention.

[0022] In the figure: 101, urine collecting bucket; 102, extension neck; 103, gripping piece; 104, gripping hole; 105, buffer ring; 106, inflation cavity; 107, anti-reflux valve; 108, internal frame tube; 109, splash plate; 110, seepage hole; 201, lower connecting hose; 202, one-way valve; 203, urine bag; 204, connecting plate; 205, clamping tube clamp; 206, pulling tube groove; 207, lower three-way hose; 208, sampling hose; 209, emptying hose; 210, emptying hard Pipe head; 211, connecting valve body; 212, valve shaft; 213, valve ball; 214, sealing ring; 215, twist plate; 301, hydraulic pressure exhaust cover; 302, upper pressing plate; 303, rubber plug piercing needle; 304, rubber needle cover; 305, sliding cylinder; 306, anti-slip head; 307, guide ridge; 308, reset spring; 401, connecting cylinder; 402, lower pressing plate; 403, anti-bias sliding groove; 501, sealing shell; 502, limit ring; 503, vacuum test tube; 504, rubber sealing plug. DETAILED DESCRIPTION

[0023] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0024] See also Figure 1-9 A self-service sampling device for tumor marker detection includes: a disposable receiving mechanism, a disposable pre-storage mechanism is arranged at the bottom of the disposable receiving mechanism, a disposable puncturing mechanism is arranged at the bottom of the disposable pre-storage mechanism, a disposable tube clamping mechanism is arranged at the bottom of the disposable puncturing mechanism, and a vacuum liquid extraction storage mechanism is installed at the bottom of the disposable tube clamping mechanism. Through the disposable receiving mechanism, disposable pre-storage mechanism, disposable puncturing mechanism, disposable tube clamping mechanism and vacuum liquid extraction storage mechanism, a urine bag 203 can be used to temporarily store a urine volume during use, and the urethra outlet can be covered by the urine receiving cover 101, so as to avoid receiving urine in the middle of urination, ensure stable receiving, and avoid urine splashing.

[0025] Among them; the disposable receiving mechanism includes a urine collecting bucket 101, an extension neck 102, a holding piece 103 and a holding hole 104, the extension neck 102 is integrally arranged at the bottom of the urine collecting bucket 101, and the material of the urine collecting bucket 101 and the material of the extension neck 102 are both light-transmitting materials, the holding piece 103 is integrally arranged on the surface of the urine collecting bucket 101, and the holding hole 104 is opened through the surface of the urine collecting bucket 101.

[0026] Among them; the disposable receiving mechanism also includes a buffer ring 105, an inflation cavity 106 and an anti-backflow valve 107, the buffer ring 105 is fixedly connected to the surface of the urine collecting bucket 101, and the buffer ring 105 corresponds to the edge of the urine collecting bucket 101, the inflation cavity 106 is opened inside the buffer ring 105, and the inside of the inflation cavity 106 is filled with air, the anti-backflow valve 107 is integrally arranged on the surface of the buffer ring 105, and the anti-backflow valve 107 is located inside the urine collecting bucket 101, and the anti-backflow valve 107 faces the side of the urine collecting bucket 101 close to the extension neck 102.

[0027] The disposable receiving mechanism further comprises an inner frame tube 108, a splash-proof sheet 109 and a seepage hole 110. The inner frame tube 108 is fixedly connected to the inner wall of the extension neck 102 away from the end of the urine receiving cover 101. The splash-proof sheet 109 is fixedly connected to the inner wall of the inner frame tube 108. The seepage hole 110 is opened on the surface of the splash-proof sheet 109. The urine receiving cover 101, the extension neck 102, the holding sheet 103, the holding hole 104, the buffer ring 103 and the holding hole 104 are arranged. 105, inflation cavity 106, anti-reflux valve 107, internal frame tube 108, splash-proof sheet 109 and seepage hole 110 can imitate the shape of the mouth of a chamber pot through the urine collecting bucket 101 and the extension neck 102 when in use, so as to ensure that the urethral outlet can be wrapped to suit the different physiological structures of men and women and ensure accuracy. At the same time, the splash-proof sheet 109 can be used to avoid splashing, and the anti-reflux valve 107 can be used to prevent the residual urine on the inner wall of the urine collecting bucket 101 from flowing back when it is tilted.

[0028] Among them; the disposable pre-storage mechanism includes a lower hose 201, a one-way valve 202, a urine bag 203, a connecting plate 204, a tube clamp 205 and a tube pulling groove 206. The lower hose 201 is fixedly connected to the bottom end of the extension neck 102, the one-way valve 202 is fixedly installed in the middle of the lower hose 201, and the one-way valve 202 is conductive in the direction away from the extension neck 102. The urine bag 203 is fixedly connected to the bottom end of the lower hose 201. There are two connecting plates 204, and the two connecting plates 204 are respectively fixedly connected to the surfaces on both sides of the urine bag 203. The tube clamp 205 is integrally arranged on the surface of the connecting plate 204, and the tube pulling groove 206 is embedded in the middle of the tube clamp 205.

[0029] Among them; the disposable pre-storage mechanism also includes a lower three-way hose 207, a sampling hose 208, an emptying hose 209 and an emptying hard pipe head 210. The lower three-way hose 207 is fixedly connected to the bottom end of the urine bag 203. The main output end of the lower three-way hose 207 and the branch output end of the lower three-way hose 207 are both provided with switch valves. The sampling hose 208 is fixedly connected to the main output end of the lower three-way hose 207 through the switch valve. The emptying hose 209 is fixedly connected to the branch output end of the lower three-way hose 207 through another switch valve. The emptying hard pipe head 210 is fixedly connected to the output end of the emptying hose 209.

[0030] The switch valve includes a connecting valve body 211, a valve shaft 212, a valve ball 213, a sealing ring 214 and a twisting piece 215. The number of connecting valve bodies 211 is two, and the two connecting valve bodies 211 are respectively fixedly connected between the main output end of the lower three-way hose 207 and the sampling hose 208 and between the branch output end of the lower three-way hose 207 and the emptying hose 209. The valve shaft 212 is rotatably connected to the inside of the connecting valve body 211, the valve ball 213 is fixedly connected to one end of the valve shaft 212, and the sealing ring 214 is fixedly connected to the inner wall of the connecting valve body 211, and the surface of the sealing ring 214 is in contact with the valve shaft. The surface of valve shaft 212 is slidably connected, and twist piece 215 is fixedly connected to one end of valve shaft 212. Through the lower hose 201, one-way valve 202, urine bag 203, connecting plate 204, tube clamp 205, tube pulling groove 206, lower three-way hose 207, sampling hose 208, emptying hose 209, emptying hard tube head 210, connecting valve body 211, valve shaft 212, valve ball 213, sealing ring 214 and twist piece 215, urine volume can be temporarily stored during use, ensuring that the patient can perform self-service sampling after urination, avoiding the inconvenience of sampling midway.

[0031] The disposable puncture mechanism includes a hydraulic pressure discharge cover 301, an upper pressing plate 302, a rubber plug puncture needle 303, a rubber needle cover 304, a slide cylinder 305, an anti-slip head 306, a guide ridge 307 and a reset spring 308. The hydraulic pressure discharge cover 301 is fixedly connected to the output end of the sampling hose 208, the upper pressing plate 302 is integrally arranged on the surface of the hydraulic pressure discharge cover 301, the rubber plug puncture needle 303 is fixedly inserted into the interior of the hydraulic pressure discharge cover 301, the rubber needle cover 304 is fixedly sleeved on one end of the rubber plug puncture needle 303, and the slide cylinder 305 is integrally arranged. At the bottom of the hydraulic pressure discharge hood 301, the anti-slip head 306 and the guide ridge 307 are integrally arranged on the surface of the slide tube 305, and the reset spring 308 is movably sleeved on the surface of the slide tube 305. Through the hydraulic pressure discharge hood 301, the upper pressing plate 302, the rubber plug piercing needle 303, the rubber needle cover 304, the slide tube 305, the anti-slip head 306, the guide ridge 307 and the reset spring 308, the rubber plug piercing needle 303 can pierce the rubber sealing plug 504 during sampling, so that the vacuum test tube 503 is connected with the urine bag 203, thereby realizing sampling.

[0032] Among them; the disposable tube clamping mechanism includes a connecting tube 401, a lower pressing piece 402 and an anti-deflection slide groove 403, the connecting tube 401 is slidably connected to the surface of the slide tube 305, the lower pressing piece 402 is integrally arranged on the surface of the connecting tube 401, the reset spring 308 is located between the lower pressing piece 402 and the upper pressing piece 302, the anti-deflection slide groove 403 is opened on the inner wall of the connecting tube 401, and the inner wall of the anti-deflection slide groove 403 is slidably connected to the surface of the guide slide ridge 307, and the inner wall of the connecting tube 401 is provided with an internal thread, through the setting of the connecting tube 401, the lower pressing piece 402 and the anti-deflection slide groove 403, the vacuum test tube 503 can be fixed when in use, and the lower pressing piece 402 is used to cooperate with the force when sampling to ensure the insertion of the stopper puncture needle 303.

[0033] Among them; the vacuum liquid extraction and storage mechanism includes a sealing shell 501, a limiting ring 502, a vacuum test tube 503 and a rubber sealing plug 504, the surface of the sealing shell 501 is provided with an external thread, and the sealing shell 501 is threadedly connected to the connecting tube 401 through the external thread and the internal thread, the limiting ring 502 is integrally arranged on the surface of the sealing shell 501, the vacuum test tube 503 is fixedly connected to the bottom of the sealing shell 501, and the rubber sealing plug 504 is fixedly connected between the sealing shell 501 and the vacuum test tube 503. Through the provided sealing shell 501, the limiting ring 502, the vacuum test tube 503 and the rubber sealing plug 504, the urine in the urine bag 203 can be sucked into the vacuum test tube 503 through the negative pressure formed by the vacuum inside the vacuum test tube 503 during sampling, and after sampling, the sealing of the rubber sealing plug 504 is used to prevent the urine from easily shaking and flowing out.

[0034] Working principle: when in use, first open the valve on the surface of the emptying hose 209, and when opening, twist the twist piece 215, and the twist piece 215 drives the valve ball 213 to rotate through the valve shaft 212, so as to achieve the unblocking of the valve ball 213, and then press to discharge the air inside the urine bag 203, so that the urine bag 203 shrinks, and then close the two valves, wind the sampling hose 208 and the emptying hose 209 upwards, and clamp them inside the two clamping clamps 205 respectively to prevent them from dragging, and then connect The urine mask 101 is aligned with the urethra opening for urination. At this time, urine is discharged into the urine mask 101 and the extension neck 102, and then passes through the one-way valve 202 along the lower connecting hose 201 into the urine bag 203 and is stored. After urination, the sampling hose 208 and the emptying hose 209 are removed from the clamp 205, and then the sealing shell 501 is twisted into the connecting tube 401, and then the upper pressing piece 302 and the lower pressing piece 402 are pressed, so that the rubber plug piercing needle 303 pierces the rubber needle cover. 304 and the rubber sealing plug 504 enter the vacuum tube 503, and then open the valve above the sampling hose 208. At this time, the negative pressure inside the vacuum tube 503 sucks the urine in the urine bag 203 into the vacuum tube 503 along the three-way hose 207 at the bottom, the valve, the sampling hose 208 and the rubber plug piercing needle 303. After a certain amount of urine is sucked in, close the valve above the sampling hose 208, and then release the pressure on the upper pressing piece 302 and the lower pressing piece 402, so that The return spring 308 squeezes the upper pressing piece 302 and the lower pressing piece 402 to separate, so that the rubber plug puncturing needle 303 is pulled out from the inside of the rubber sealing plug 504, and then the sealing shell 501 is twisted to take out the vacuum test tube 503 from the connecting tube 401, and then the emptying hard tube head 210 is aimed at the toilet or squat toilet, and the valve above it is opened to discharge the remaining urine in the urine bag 203, and then the vacuum liquid extraction storage mechanism is left, and the other components are discarded to the designated location, thereby realizing self-service sampling.

[0035] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A self-service sampling device for tumor marker detection, characterized in that: include: A disposable receiving mechanism, a disposable pre-storage mechanism is arranged at the bottom of the disposable receiving mechanism, a disposable puncture mechanism is arranged at the bottom of the disposable pre-storage mechanism, a disposable tube clamping mechanism is arranged at the bottom of the disposable puncture mechanism, and a vacuum liquid extraction storage mechanism is installed at the bottom of the disposable tube clamping mechanism.

2. A self-service sampling device for tumor marker detection according to claim 1, characterized in that: The disposable receiving mechanism comprises a urine receiving bucket (101), an extension neck (102), a holding piece (103) and a holding hole (104); the extension neck (102) is integrally arranged at the bottom of the urine receiving bucket (101); the material of the urine receiving bucket (101) and the material of the extension neck (102) are both light-transmitting materials; the holding piece (103) is integrally arranged on the surface of the urine receiving bucket (101); and the holding hole (104) is penetrated and opened on the surface of the urine receiving bucket (101).

3. A self-service sampling device for tumor marker detection according to claim 2, characterized in that: The disposable receiving mechanism further comprises a buffer ring (105), an inflation chamber (106) and an anti-backflow valve (107); the buffer ring (105) is fixedly connected to the surface of the urine receiving hopper (101), and the buffer ring (105) corresponds to the edge of the urine receiving hopper (101); the inflation chamber (106) is arranged inside the buffer ring (105), and the inside of the inflation chamber (106) is filled with air; the anti-backflow valve (107) is integrally arranged on the surface of the buffer ring (105), and the anti-backflow valve (107) is located inside the urine receiving hopper (101), and the anti-backflow valve (107) faces the side of the urine receiving hopper (101) close to the extension neck (102).

4. A self-service sampling device for tumor marker detection according to claim 2, characterized in that: The disposable receiving mechanism further comprises an inner frame tube (108), a splash-proof sheet (109) and a seepage hole (110); the inner frame tube (108) is fixedly connected to the inner wall of the extension neck (102) at one end away from the urine receiving cover (101); the splash-proof sheet (109) is fixedly connected to the inner wall of the inner frame tube (108); and the seepage hole (110) is formed through the surface of the splash-proof sheet (109).

5. The self-service sampling device for tumor marker detection according to claim 2, characterized in that: The disposable pre-storage mechanism comprises a lower connecting hose (201), a one-way valve (202), a urine bag (203), a connecting plate (204), a tube clamp (205) and a tube drawing groove (206); the lower connecting hose (201) is fixedly connected to the bottom end of the extension neck (102); the one-way valve (202) is fixedly installed in the middle of the lower connecting hose (201), and the one-way valve (202) is conductive in a direction away from the extension neck (102); the urine bag (203) is fixedly connected to the bottom end of the lower connecting hose (201); there are two connecting plates (204), and the two connecting plates (204) are respectively fixedly connected to the surfaces of both sides of the urine bag (203); the tube clamp (205) is integrally arranged on the surface of the connecting plate (204); and the tube drawing groove (206) is embedded in the middle of the tube clamp (205).

6. A self-service sampling device for tumor marker detection according to claim 5, characterized in that: The disposable pre-storage mechanism further comprises a three-way hose (207) at the bottom, a sampling hose (208), an emptying hose (209) and an emptying hard pipe head (210); the three-way hose (207) at the bottom is fixedly connected to the bottom end of the urine bag (203); a main output end of the three-way hose (207) and a branch output end of the three-way hose (207) are both provided with a switch valve; the sampling hose (208) is fixedly connected to the main output end of the three-way hose (207) at the bottom through the switch valve; the emptying hose (209) is fixedly connected to the branch output end of the three-way hose (207) at the bottom through another switch valve; and the emptying hard pipe head (210) is fixedly connected to the output end of the emptying hose (209).

7. A self-service sampling device for tumor marker detection according to claim 6, characterized in that: The switch valve comprises a connecting valve body (211), a valve shaft (212), a valve ball (213), a sealing ring (214) and a twisting plate (215). The number of the connecting valve bodies (211) is two, and the two connecting valve bodies (211) are respectively fixedly connected between the main output end of the lower three-way hose (207) and the sampling hose (208) and between the branch output end of the lower three-way hose (207) and the drain hose (209). The valve shaft (212) is rotatably connected to the inside of the connecting valve body (211), the valve ball (213) is fixedly connected to one end of the valve shaft (212), the sealing ring (214) is fixedly connected to the inner wall of the connecting valve body (211), and the surface of the sealing ring (214) is slidably connected to the surface of the valve shaft (212), and the twisting plate (215) is fixedly connected to one end of the valve shaft (212).

8. The self-service sampling device for tumor marker detection according to claim 6, characterized in that: The disposable puncturing mechanism comprises a hydraulic pressure discharge cover (301), an upper pressing plate (302), a rubber plug puncturing needle (303), a rubber needle cover (304), a slide cylinder (305), an anti-slipping head (306), a guide sliding ridge (307) and a reset spring (308). The hydraulic pressure discharge cover (301) is fixedly connected to the output end of the sampling hose (208), the upper pressing plate (302) is integrally arranged on the surface of the hydraulic pressure discharge cover (301), the rubber plug puncturing needle (303) is fixedly inserted into the interior of the hydraulic pressure discharge cover (301), the rubber needle cover (304) is fixedly sleeved on one end of the rubber plug puncturing needle (303), the slide cylinder (305) is integrally arranged at the bottom of the hydraulic pressure discharge cover (301), the anti-slipping head (306) and the guide sliding ridge (307) are both integrally arranged on the surface of the slide cylinder (305), and the reset spring (308) is movably sleeved on the surface of the slide cylinder (305).

9. A self-service sampling device for tumor marker detection according to claim 8, characterized in that: The disposable tube clamping mechanism comprises a connecting tube (401), a lower pressing plate (402) and an anti-deflection slide groove (403); the connecting tube (401) is slidably connected to the surface of the slide tube (305); the lower pressing plate (402) is integrally arranged on the surface of the connecting tube (401); the return spring (308) is located between the lower pressing plate (402) and the upper pressing plate (302); the anti-deflection slide groove (403) is provided on the inner wall of the connecting tube (401); the inner wall of the anti-deflection slide groove (403) is slidably connected to the surface of the guide slide ridge (307); and the inner wall of the connecting tube (401) is provided with an internal thread.

10. The self-service sampling device for tumor marker detection according to claim 9, characterized in that: The vacuum liquid extraction and storage mechanism comprises a sealing shell (501), a limiting ring (502), a vacuum test tube (503) and a rubber sealing plug (504); the surface of the sealing shell (501) is provided with an external thread, and the sealing shell (501) is threadedly connected to the connecting tube (401) via the external thread and the internal thread; the limiting ring (502) is integrally provided on the surface of the sealing shell (501); the vacuum test tube (503) is fixedly connected to the bottom of the sealing shell (501); and the rubber sealing plug (504) is fixedly connected between the sealing shell (501) and the vacuum test tube (503).

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