Traditional Chinese medicine composition for treating bone fracture as well as preparation method and application of traditional Chinese medicine composition

Abstract

The invention discloses a traditional Chinese medicine composition for treating bone fracture and a preparation method thereof. Through a large number of clinical practices, dragon's blood, broccoli, teasel root, ligusticum wallichii, native copper, frankincense, myrrh, dragon bone, ground beetle, amber, flatstem milkvetch seed, raspberry, astragalus membranaceus, angelica sinensis and bighead atractylodes rhizome are selected as raw materials and are prepared into an oral dosage form according to a weight ratio. Clinical verifications prove that the traditional Chinese medicine is remarkable in curative effect, free of toxic and side effects and good in safety. By using the traditional Chinese medicine composition prepared by the invention, the recovery time of bone fractures can be shortened, and the cure rate of various bone fractures can be improved.

Description

Technical Field

[0001] The invention relates to the technical field of Chinese medicine compositions, in particular to a Chinese medicine formula for treating bone injuries and a preparation method thereof. Background Art

[0002] The treatment of bone injuries mainly includes the treatment of fractures and joint injuries. Both injuries require a comprehensive treatment plan, including conservative treatment, surgical treatment, and rehabilitation training. If it is only a mild patellar cartilage injury without a fracture, you can cooperate with the doctor to receive conservative treatment. Commonly used conservative treatment methods in clinical practice include quadriceps exercise, knee pads, external application of anti-inflammatory and analgesic gels such as Fastone and Voltaren, and intra-articular injection of lubricant sodium hyaluronate. If the condition is more serious and conservative treatment alone is not effective, you can consider surgical treatment. Currently, commonly used surgical treatment methods in clinical practice include intra-articular injection of platelet-rich plasma, limited cartilage resection and drilling, artificial joint replacement, cartilage transplantation, etc. There is no solution for comminuted fractures except amputation. It is difficult to completely heal bone fractures in 7-10 months, and severe cases have not recovered for 1 year. In addition, it is necessary to cooperate with anti-inflammatory injections, Chinese medicine fumigation, etc., which basically have little effect, and the patient's own recovery is the main thing, which causes great pain to the patient and costs a huge amount of money. There is a lack of effective bone-setting and bone-regenerating drugs. Summary of the invention

[0003] Purpose of the present invention: In order to overcome the defects of the prior art, the present invention provides a Chinese medicine formula for treating bone injuries and a preparation method thereof, aiming to solve the problem of insufficient efficacy of bone injury symptoms.

[0004] The first technical solution of the present invention is a traditional Chinese medicine formula for treating bone injuries, comprising the following main components in parts by weight: 10-15 parts of Sanguisorba officinalis, 6-10 parts of Western Flos Occidentalis, 10-15 parts of Dipsacus asper, 10-15 parts of Ligusticum chuanxiong, 5-10 parts of natural copper, 6-10 parts of frankincense, 6-10 parts of myrrh, 20-30 parts of dragon bones, 6-10 parts of Eupolyphaga sinensis, 10-15 parts of amber, 20-25 parts of Astragalus membranaceus, 10-15 parts of Rubus idaeus, 12-15 parts of Astragalus membranaceus, 15-20 parts of Angelica sinensis, and 10-15 parts of Atractylodes macrocephala.

[0005] Preferably, 15 parts of Sanguisorba officinalis, 6 parts of Western Flos, 10 parts of Dipsacus asper, 10 parts of Ligusticum chuanxiong, 10 parts of natural copper, 9 parts of frankincense, 9 parts of myrrh, 30 parts of Dragon Bones, 6 parts of Eupolyphaga sinensis, 10 parts of Amber, 20 parts of Astragalus membranaceus, 15 parts of Rubus idaeus, 15 parts of Astragalus, 20 parts of Angelica sinensis, and 15 parts of Atractylodes macrocephala.

[0006] The following is a detailed description of the effects of each herb in the formula:

[0007] Xuejie: ​​It is pungent and neutral in nature. It enters the liver and heart meridians. It has the effects of removing blood stasis and relieving pain, stopping bleeding and healing sores. In the formula, Xuejie mainly promotes the healing of wounds. It is used in combination with frankincense, myrrh and other drugs to enhance the effect of removing blood stasis and relieving pain.

[0008] Xihua: It is mild and slightly cold, and has the effects of cooling blood and detoxifying, promoting blood circulation and removing blood stasis, relieving depression and calming the mind. In the formula, it mainly plays the role of promoting blood circulation and removing blood stasis, cooling blood and detoxifying, and relieving depression and calming the mind.

[0009] Dipsacus root: bitter, pungent, slightly warm; its efficacy is to nourish the liver and kidney, strengthen the tendons and bones, stop bleeding and stabilize the fetus, and heal wounds and fractures. In the formula, it mainly plays the role of promoting blood circulation, removing blood stasis, healing tendons and healing wounds, and it can also play the role of nourishing the liver and kidney and strengthening tendons and bones.

[0010] Chuanxiong: It is pungent and warm in nature and enters the liver meridian. It has the effects of promoting blood circulation, promoting qi, dispelling wind and relieving pain. In the formula, it mainly plays the role of promoting blood circulation, promoting blood circulation and removing blood stasis, dispelling wind and relieving pain.

[0011] Frankincense: It is pungent, bitter and warm in nature and flavor. It enters the heart, liver and spleen meridians and has the effects of promoting blood circulation, relieving pain and promoting tissue regeneration. In the formula, it mainly plays the role of promoting blood circulation and removing blood stasis, relieving pain caused by blood stasis and relieving pain.

[0012] Natural copper: It is pungent, bitter and flat in nature. It is used for the treatment of traumatic injuries. It has the effect of dispersing blood stasis and relieving pain. It can also be used to fix bones and tendons. It is used for traumatic injuries. In the formula, it mainly plays the role of dispersing blood stasis and relieving pain, and fixing bones and tendons.

[0013] Earthworm: cold in nature, salty in taste, slightly toxic, and enters the liver meridian. In the formula, it mainly plays the role of breaking blood, removing blood stasis, and dispersing the stagnation of the body.

[0014] Myrrh: It is pungent, bitter, and neutral in nature. It enters the heart meridian, liver meridian, and spleen meridian. The effects and functions of myrrh are to disperse blood stasis, relieve pain, and reduce swelling and promote tissue regeneration. In the formula, it mainly plays the role of dispersing qi stagnation, promoting blood circulation and removing blood stasis, and promoting blood circulation and relieving pain.

[0015] Dragon bone: sweet, astringent, flat in nature, enters the heart, liver, and kidney meridians. In the formula, it mainly plays the role of calming the mind, calming the liver, suppressing yang, astringing and consolidating, promoting tissue regeneration and healing sores.

[0016] Turtle shell: sweet and salty in taste, cold in nature, enters the liver, kidney, and heart meridians. In the formula, it mainly plays the role of nourishing yin and suppressing yang, benefiting the kidneys and strengthening bones, and consolidating menstruation and stopping metrorrhagia.

[0017] Astragalus: a sweet and warm product, it enters the liver and kidney meridians. In the formula, it mainly plays the role of nourishing the liver, benefiting the kidney, improving eyesight, and consolidating essence.

[0018] Raspberry: sweet, sour, warm in nature, enters the liver, kidney, and bladder meridians. In the formula, it mainly plays the role of nourishing the liver and kidney, astringing sperm, reducing urine, and improving eyesight.

[0019] Astragalus: sweet, warm, enters the spleen and lung meridians. In the formula, it mainly plays the role of replenishing qi and raising yang, strengthening the body's defense system, promoting diuresis and reducing swelling, and supporting sores and promoting tissue regeneration.

[0020] Angelica sinensis: warm in nature, sweet and spicy in taste, enters the heart, liver and spleen meridians. In the formula, it mainly plays the role of nourishing blood, regulating menstruation and relieving pain, moisturizing and lubricating the intestines.

[0021] Atractylodes macrocephala: warm in nature, bitter and sweet in taste, enters the spleen and stomach meridians. In the formula, it mainly plays the role of strengthening the spleen and replenishing qi, drying dampness and promoting diuresis, stopping sweat and stabilizing pregnancy.

[0022] The prescription of the present invention uses Dipsacus asper, Ligusticum chuanxiong, frankincense and natural copper as main medicines, and has the main effects of promoting blood circulation and removing blood stasis, repairing tendons and healing wounds, promoting blood circulation and promoting qi, dispelling wind and relieving pain, promoting blood circulation, nourishing the liver and kidneys, strengthening tendons and bones, and healing wounds and repairing fractures. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 This is a comparison diagram of case 1 before and after treatment of the present invention;

[0024] In the figure:

[0025] 1. Bone injury image before treatment; 2. Bone injury image after treatment. DETAILED DESCRIPTION

[0026] Embodiment 1

[0027] 15 parts of Sanguisorba officinalis, 6 parts of Western Flos Occidentalis, 10 parts of Dipsacus asper, 10 parts of Chuanxiong, 10 parts of natural copper, 9 parts of frankincense, 9 parts of myrrh, 30 parts of dragon bones, 6 parts of Eupolyphaga sinensis, 10 parts of amber, 20 parts of Astragalus membranaceus, 15 parts of Rubus idaeus, 15 parts of Astragalus, 20 parts of Angelica sinensis, 15 parts of Atractylodes macrocephala, dragon bones and tortoise shells are calcined at 100 DEG C, natural copper is calcined by vinegar, and other raw materials are extracted, comprising the following steps: washing the raw materials, drying them at 45-60 DEG C, crushing the dried Chinese medicinal materials into 0.2-0.5 cm particles respectively, and then mixing them.

[0028] Embodiment 2

[0029] 10 parts of Sanguisorba officinalis, 9 parts of Western Flos, 15 parts of Dipsacus asper, 10 parts of Chuanxiong, 10 parts of natural copper, 10 parts of frankincense, 9 parts of myrrh, 20 parts of dragon bones, 10 parts of Eupolyphaga sinensis, 12 parts of amber, 20 parts of Astragalus, 15 parts of Rubus idaeus, 15 parts of Astragalus, 20 parts of Angelica sinensis, and 15 parts of Atractylodes macrocephala. Dragon bones and tortoise shells are calcined at 100°C, natural copper is calcined with vinegar, and other raw materials are extracted, including the following steps: after washing the raw materials, drying them at 45-60°C, crushing the dried Chinese medicinal materials into 0.2-0.5cm particles respectively and mixing them.

[0030] Embodiment 3

[0031] 12 parts of dragon's blood, 10 parts of western flower, 10 parts of Dipsacus asper, 10 parts of Chuanxiong, 10 parts of natural copper, 6 parts of frankincense, 9 parts of myrrh, 30 parts of dragon's bone, 6 parts of Eupolyphaga sinensis, 15 parts of amber, 20 parts of Astragalus, 10 parts of Rubus idaeus, 12 parts of Astragalus, 25 parts of Angelica sinensis, and 15 parts of Atractylodes macrocephala. Dragon's bone and tortoise shell are calcined at 100°C, natural copper is calcined with vinegar, and other raw materials are extracted, including the following steps: after washing the raw materials, drying them at 45-60°C, crushing the dried Chinese medicinal materials into 0.2-0.5cm particles respectively and mixing them.

[0032] Embodiment 4

[0033] 10 parts of Sanguisorba officinalis, 10 parts of Western Flos odoratis, 12 parts of Dipsacus asper, 15 parts of Chuanxiong, 9 parts of natural copper, 10 parts of frankincense, 6 parts of myrrh, 25 parts of dragon bones, 9 parts of Eupolyphaga sinensis, 15 parts of amber, 25 parts of Astragalus membranaceus, 12 parts of Rubus idaeus, 12 parts of Astragalus, 20 parts of Angelica sinensis, and 10 parts of Atractylodes macrocephala. Dragon bones and tortoise shells are calcined at 100°C, natural copper is calcined with vinegar, and other raw materials are extracted, including the following steps: after washing the raw materials, drying at 45-60°C, crushing the dried Chinese medicinal materials into 0.2-0.5cm particles respectively and mixing them.

[0034] Embodiment 5

[0035] 15 parts of dragon's blood, 10 parts of western flower, 10 parts of Dipsacus asper, 15 parts of Chuanxiong, 5 parts of natural copper, 10 parts of frankincense, 10 parts of myrrh, 25 parts of dragon's bone, 10 parts of Eupolyphaga sinensis, 10 parts of amber, 20 parts of Astragalus, 15 parts of Rubus idaeus, 15 parts of Astragalus, 15 parts of Angelica sinensis, and 15 parts of Atractylodes macrocephala. Dragon's bone and tortoise shell are calcined at 100°C, natural copper is calcined with vinegar, and other raw materials are extracted, including the following steps: after washing the raw materials, drying them at 45-60°C, crushing the dried Chinese medicinal materials into 0.2-0.5cm particles respectively and mixing them.

[0036] In order to demonstrate the therapeutic effect of the medicine of the present invention, the therapeutic effect of the Chinese medicine formula of the present invention is analyzed in combination with actual cases.

[0037] 1. Gao xx, female, 52 years old. Right ankle fracture, treated with manipulation and small splint. Take the prescription of the patent, 9 grams each time, three times a day and night, and it is completely healed after one month.

[0038] 2. Bi xx, male, 40 years old. When he was treated on July 9, 2023, he had great difficulty walking and limited lumbar function. The lumbar MRI film diagnosed that it was an old injury and lumbar joint dislocation. Through manipulation and taking the prescription described in the patent of this invention, taking nine grams each time, three times a day and night, he was completely healed after one month of taking it.

[0039] 3. Wang xx, male, 36 years old, came to the hospital for treatment on May 24, 2024, with sacroiliac joint laceration. He was treated through manipulation and the prescription described in the patent of this invention, taking nine grams each time, three times a day and night. After one month, all symptoms disappeared and he returned to his construction job.

Claims

1. A Chinese medicine formula for treating bone injuries, characterized in that: The invention comprises the following main components in parts by weight: 10-15 parts of dragon's blood, 6-10 parts of western flower, 10-15 parts of dipsaci, 10-15 parts of ligusticum chuanxiong, 5-10 parts of natural copper, 6-10 parts of frankincense, 6-10 parts of myrrh, 20-30 parts of dragon's bones, 6-10 parts of earthworm, 10-15 parts of amber, 20-25 parts of complanatus seeds, 10-15 parts of raspberry, 12-15 parts of astragalus, 15-20 parts of angelica and 10-15 parts of atractylodes.

2. The Chinese medicine formula for treating bone injuries according to claim 1, characterized in that: The invention comprises the following main components in parts by weight: 15 parts of Sanguisorba officinalis, 6 parts of Western Flos Occidentalis, 10 parts of Dipsacus asper, 10 parts of Chuanxiong, 10 parts of Natural Copper, 9 parts of Frankincense, 9 parts of Myrrh, 30 parts of Dragon Bones, 6 parts of Eupolyphaga sinensis, 10 parts of Amber, 20 parts of Astragalus membranaceus, 15 parts of Rubus idaeus, 15 parts of Astragalus, 20 parts of Angelica sinensis and 15 parts of Atractylodes macrocephala.

3. A method for preparing a Chinese medicine formula for treating bone injuries, characterized in that: Dragon bones and tortoise shells are calcined at 100°C (or the powder is fried in a pan until it turns yellow for easier absorption, increasing the amount absorbed and accelerating the effectiveness of the drug in the body).

4. A method for preparing a Chinese medicine formula for treating bone injuries, characterized in that: Natural copper is calcined in vinegar. Specifically, the natural copper is heated red with fire and then placed in vinegar for cold or hot expansion to reduce the hardness of the mineral and facilitate absorption. After being cold expanded with vinegar, it is easy to be crushed and absorbed.

5. A method for preparing a Chinese medicine formula for treating bone injuries, characterized in that: The added vinegar is sour in nature and flavor. Sourness can solidify and astringency can solidify essence. Essence is produced by the kidneys, which can strengthen the kidneys and strengthen the bones.

6. A method for preparing a Chinese medicine formula for treating bone injuries, characterized in that: The added amber has the effects of calming the nerves, dispersing blood stasis and stopping bleeding.

7. A method for preparing a Chinese medicine formula for treating bone injuries, characterized in that: The other raw materials are extracted, including the following steps: washing the raw materials, drying them at 45-60° C., crushing the dried Chinese medicinal materials into 0.2-0.5 cm particles respectively, and then mixing them.

8. It should be noted that during the period of taking the Chinese medicine involved in the present invention, you should avoid: spicy, cold food, seafood, and food with feathers; meat: you can only eat: pork and mutton.

9. Contraindications: Patients with a history of hypertension and / or heart failure (such as fluid retention and edema) and pregnant women should use it with caution or prohibit it. Pregnant women with acute fractures must take the product under the supervision of a doctor and ensure their physical safety. Blood pressure must be maintained within the safe pressure range.

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