Traditional Chinese medicine composition with weight losing effect as well as preparation method and application of traditional Chinese medicine composition

Abstract

The invention discloses a traditional Chinese medicine composition with a weight losing effect and a preparation method and application thereof. The traditional Chinese medicine composition is prepared through the following steps that 5-10 parts of radix fici simplicissimae, 5-10 parts of poria cocos, 5-10 parts of coix seeds, 3-9 parts of hawthorn fruits, 1-4 parts of licorice roots, 1-4 parts of lotus leaves, 1-4 parts of cassia seeds, 0.1-2.0 parts of panax notoginseng fibrous roots, 0.1-2.0 parts of bitter gourds, 0.1-2.0 parts of orange peels and 0.01-1.0 part of Yunnan black tea are decocted with water according to the corresponding mass of a prescription, extraction is conducted, screening is conducted, medicine residues are filtered out, and an extracting solution is obtained; standing at normal temperature, sieving, concentrating, adding drinking water, stirring and dissolving, fixing the volume, filling and sealing, and sterilizing. The traditional Chinese medicine composition disclosed by the invention has a remarkable weight-losing effect, can be used for preparing functional foods or medicines with the weight-losing effect, and has an important application value.

Description

Technical Field

[0001] The invention belongs to the technical field of medicine, and in particular relates to a Chinese medicine composition with weight loss effect and a preparation method and application thereof. Background Art

[0002] According to the "Report on the Nutrition and Chronic Disease Status of Chinese Residents (2020)", more than half of adults in my country are overweight or obese. Obesity refers to a chronic metabolic disease caused by excessive total body fat content (or) increased local fat content and abnormal distribution, which is caused by the combined effects of genetic and environmental factors. A large number of studies have confirmed that obesity is a risk factor for a variety of serious diseases that endanger human health, such as diabetes, hyperlipidemia, and cardiovascular and cerebrovascular diseases.

[0003] Currently, there are five kinds of weight loss drugs approved by the FDA, such as orlistat capsules, lorcaserin, liraglutide injection, etc. While these drugs improve obesity, they also have adverse reactions that cannot be ignored; while orlistat reduces fat absorption, it also inhibits the absorption of fat-soluble vitamins, and while reducing weight, it may also cause varying degrees of liver and kidney damage; in short, Western medicine has limitations in the treatment of obesity, and finding safe and effective therapeutic drugs is the key to research in obesity.

[0004] As people's understanding of traditional Chinese medicine deepens, combined with the "Management Measures for the Catalog of Traditional Food and Chinese Medicinal Materials" (Draft for Comments) issued by the National Health Commission in 2018, a total of 100 Chinese medicines that are both food and medicine are listed. This type of Chinese medicine has minimal toxic side effects and can be taken for a long time. It has been widely used in the medical care and food industry. Therefore, it is of great practical significance to seek a convenient, safe, effective and long-term use of Chinese medicine for weight loss. Summary of the invention

[0005] The present invention aims at the deficiencies of the existing technologies and treatment methods, and provides a Chinese medicine composition for weight loss with good curative effect and its preparation method and use through experimental research, which has little toxic side effects and significant weight loss effect. In order to achieve the purpose of the present invention, the following technical scheme is proposed:

[0006] A traditional Chinese medicine composition with weight loss effect is prepared from the following raw materials, measured by weight: 5-10 parts of quinquefolius, 5-10 parts of tuckahoe, 5-10 parts of coix seeds, 3-9 parts of hawthorn, 1-4 parts of licorice, 1-4 parts of lotus leaves, 1-4 parts of cassia seeds, 0.1-2.0 parts of notoginseng root, 0.1-2.0 parts of bitter melon, 0.1-2.0 parts of tangerine peel, and 0.01-1.0 parts of Yunnan black tea.

[0007] Preferably, the Chinese medicine composition with weight loss effect is made of the following raw materials, measured by weight: 6-9 parts of ginseng, 6-9 parts of Poria cocos, 6-9 parts of coix seeds, 4-8 parts of hawthorn, 1-3 parts of licorice, 1-3 parts of lotus leaves, 1-3 parts of cassia seeds, 0.1-1.5 parts of Panax notoginseng roots, 0.1-1.5 parts of bitter gourd, 0.1-1.5 parts of tangerine peel, and 0.01-0.9 parts of Yunnan black tea.

[0008] Preferably, the Chinese medicine composition with weight loss effect is made of the following raw materials, measured by weight: 7 parts of ginseng, 7 parts of Poria cocos, 7 parts of coix seeds, 7 parts of hawthorn, 2.5 parts of licorice, 2.5 parts of lotus leaves, 2.5 parts of cassia seeds, 0.9 parts of Panax notoginseng roots, 0.8 parts of bitter melon, 0.5 parts of tangerine peel, and 0.15 parts of Yunnan black tea.

[0009] Furthermore, the present invention also provides a method for preparing the Chinese medicine composition, comprising the following steps:

[0010] (a) Add 8-15 times the amount of water to Prunus mume, Poria cocos, Coix seeds, hawthorn, licorice, lotus leaf, Cassia seed, Panax notoginseng root, bitter melon, tangerine peel, and Yunnan black tea, decoct for 1-3 hours, and pass through a 80-200 mesh sieve to obtain a first extract;

[0011] (b) adding 8-15 times the amount of water again, decocting and extracting for 1-3 hours, decocting 2-4 times in total, and filtering through a 80-200 mesh sieve to obtain an extract;

[0012] (c) combining the extracts, concentrating in vacuo to a Brix of ≥20%, standing for 12-24 hours, passing through a 100-200 mesh sieve, discarding the waste residue, and concentrating the filtrate to obtain an extract;

[0013] (d) Add the obtained extract to drinking water, heat it to 50-70° C., stir and mix, adjust the volume, fill and sterilize to obtain a Chinese medicine composition.

[0014] Preferably, the amount of water added in steps a and b is 12 times, and the decocting time is 2.5 hours.

[0015] Preferably, in step a, the solution is sieved through a 100-mesh sieve to obtain a first extract; in step b, the solution is sieved through a 200-mesh sieve to obtain an extract; and in step c, the solution is allowed to stand for 18 hours and sieved through a 200-mesh sieve.

[0016] Preferably, in step d, the mixture is heated to 65° C., stirred and mixed, fixed to volume, sealed, and sterilized to obtain a traditional Chinese medicine composition.

[0017] Furthermore, the present invention also provides a pharmaceutical preparation, which is composed of the Chinese medicine composition and a pharmaceutically acceptable carrier. The pharmaceutical preparation is an ointment, tablet, capsule, oral liquid, granule, pill, powder, suspension or syrup.

[0018] Furthermore, the present invention also provides the use of the traditional Chinese medicine composition in preparing functional food or medicine with weight loss effect.

[0019] Properties of each Chinese medicine raw material:

[0020] Five-fingered ginseng: enters the spleen, lung, and liver meridians; strengthens the spleen and lungs, promotes qi and eliminates dampness, relaxes muscles and activates collaterals; mainly treats spleen deficiency edema, tuberculosis cough, etc.

[0021] Poria: It enters the heart, lung, spleen, and kidney meridians; it promotes diuresis and eliminates dampness, strengthens the spleen, and calms the mind; it is mainly used to treat edema, phlegm and fluid, spleen deficiency diarrhea, palpitations, insomnia, etc.

[0022] Coix seed: enters the spleen, stomach, and lung meridians; promotes diuresis and eliminates dampness, strengthens the spleen and stops diarrhea, removes numbness, discharges pus, detoxifies and disperses nodules; it is mainly used to treat edema, athlete's foot, difficulty urinating, spleen deficiency diarrhea, dampness, numbness, cramps, etc.

[0023] Hawthorn: enters the spleen, stomach, liver, and lung meridians; eliminates food stagnation and resolves blood stasis; mainly treats food stagnation, abdominal distension and pain, diarrhea and dysentery

[0024] Licorice: It enters the heart, lung, spleen, and stomach meridians; it replenishes qi and nourishes the middle, moistens the lungs and relieves cough, clears away heat and detoxifies, relieves pain, and harmonizes the properties of medicines; it is mainly used to treat spleen deficiency and fatigue, heart deficiency and palpitations, cough and asthma, carbuncle and throat numbness, drug and food poisoning, and cramps and pain in the abdomen and limbs.

[0025] Lotus leaf: enters the liver, spleen, and stomach meridians; clears away heat and dampness, promotes the flow of clear yang, cools blood and stops bleeding; it is mainly used to treat summer heat and thirst, summer-damp diarrhea, spleen deficiency diarrhea, blood heat and vomiting and epistaxis, and bloody stools.

[0026] Cassia seed: enters the liver and large intestine meridians; clears the liver and improves eyesight, moistens the intestines and promotes bowel movements; mainly treats red and painful eyes, photophobia and excessive tears, headaches and dizziness, blurred vision, and constipation, etc.

[0027] Panax notoginseng fibrous roots: fibrous roots growing on the main root of Panax notoginseng; Panax notoginseng fibrous roots contain notoginseng saponins, flavonoids, notoginseng extract, polysaccharides and other effective ingredients, which have the effects of regulating blood sugar, lowering blood lipids and cholesterol, and inhibiting arteriosclerosis.

[0028] Bitter melon: enters the heart, spleen, and lung meridians; dispels summer heat, improves eyesight, and detoxifies; it is mainly used to treat summer heat, thirst, diabetes, red and painful eyes, dysentery, sores, carbuncles, and swelling.

[0029] Tangerine peel: enters the spleen and lung meridians; regulates qi and removes blood stasis, regulates the middle and stimulates appetite, dries dampness and resolves phlegm; mainly treats spleen and stomach qi stagnation, chest fullness, abdominal distension and pain, loss of appetite, phlegm and cough, etc.

[0030] Dianhong Tea: It has the effects of diuresis and anti-inflammatory, detoxification and refreshing, thirst quenching, heat clearing, stomachic and intestinal conditioning, aiding digestion, and lowering blood lipids.

[0031] Most obese patients suffer from spleen deficiency and phlegm and dampness, which are mutually causal. However, phlegm and dampness accumulate in the middle burner and easily turn into heat. Therefore, treatment should also focus on clearing heat and dampness.

[0032] Compared with the prior art, the beneficial effects of the present invention are as follows: most of the Chinese medicine compositions of the present invention are Chinese medicines with the same origin as medicine and food, which are safe and effective. Based on the theory of TCM syndrome differentiation and treatment, the Chinese medicines with the effects of promoting water and dampness, strengthening the spleen, clearing away summer heat and removing dampness are rationally formulated and matched, and the weight loss effect is remarkable. The Chinese medicine components complement each other and synergize with each other, which can reduce the body weight, Lee's index, fat wet weight, liver wet weight, fat / body ratio, etc. of rats, and at the same time reduce the content of total cholesterol, triglyceride, low-density lipoprotein, etc. in serum, and increase the content of high-density lipoprotein in serum, which has very significant effect in weight loss, and the preparation method is simple, safe and convenient to use, and is an effective Chinese medicine prescription with weight loss effect. DETAILED DESCRIPTION

[0033] In order to better understand the present invention, the embodiments of the present invention are described in detail below in conjunction with examples. However, those skilled in the art will understand that the following examples are only used to illustrate the present invention and should not be construed as limiting the scope of the present invention.

[0034] Example 1

[0035] A Chinese medicine composition with weight loss effect is composed of the following raw materials: 10 parts of quinquefolius, 10 parts of tuckahoe, 10 parts of coix seeds, 9 parts of hawthorn, 4 parts of licorice, 4 parts of lotus leaves, 4 parts of cassia seeds, 2 parts of notoginseng roots, 2 parts of bitter melon, 2 parts of tangerine peel, and 1.0 part of Yunnan black tea.

[0036] Example 2

[0037] A Chinese medicine composition with weight loss effect, composed of the following raw materials: 5 parts of quinquefolius, 5 parts of tuckahoe, 5 parts of coix seeds, 3 parts of hawthorn, 1 part of licorice, 1 part of lotus leaf, 1 part of cassia seed, 0.1 part of notoginseng root, 0.1 part of bitter melon, 0.1 part of tangerine peel, and 0.01 part of Yunnan black tea.

[0038] Example 3

[0039] A Chinese medicine composition with weight loss effect, composed of the following raw materials: 8 parts of quinquefolius, 7.5 parts of tuckahoe, 8.5 parts of coix seeds, 6 parts of hawthorn, 3 parts of licorice, 3 parts of lotus leaves, 3 parts of cassia seeds, 1.2 parts of notoginseng roots, 1.5 parts of bitter melon, 1.0 part of tangerine peel, and 0.4 part of Yunnan black tea.

[0040] Example 4

[0041] A Chinese medicine composition with weight loss effect is prepared by taking the raw materials in Example 3. The specific preparation method is:

[0042] (a) Add 8 times the amount of water to Prunus mume, Poria cocos, Coix seeds, hawthorn, licorice, lotus leaf, Cassia seed, Panax notoginseng root, bitter melon, tangerine peel, and Yunnan black tea, boil and extract for 2.5 hours, and pass through a 100-mesh sieve to obtain the first extract;

[0043] (b) adding 8 times the amount of water again, boiling and extracting for 2.5 hours, boiling twice in total, and filtering through a 200-mesh sieve to obtain an extract;

[0044] (c) combining the extracts, concentrating in vacuo to a Brix of ≥20%, standing for 12 h, passing through a 100-mesh sieve, discarding the waste residue, and concentrating the filtrate to obtain an extract;

[0045] (d) adding the obtained extract to drinking water, heating the mixture to 50° C., stirring and mixing, fixing the volume, filling and sterilizing the mixture to obtain the compound weight loss cream.

[0046] Example 5

[0047] A Chinese medicine composition with weight loss effect is prepared by taking the raw materials in Example 3. The specific preparation method is:

[0048] (a) Add 12 times the amount of water to Prunus mume, Poria cocos, Coix seeds, hawthorn, licorice, lotus leaf, Cassia seed, Panax notoginseng root, bitter melon, tangerine peel, and Yunnan black tea, boil and extract for 2.5 hours, and pass through a 100-mesh sieve to obtain the first extract;

[0049] (b) adding 12 times the amount of water again, boiling and extracting for 2.5 hours, boiling for a total of 3 times, and filtering through a 200-mesh sieve to obtain an extract;

[0050] (c) combining the extracts, concentrating in vacuo to a Brix of ≥20%, standing for 18 h, passing through a 200-mesh sieve, discarding the waste residue, and concentrating the filtrate to obtain an extract;

[0051] (d) adding the obtained extract to drinking water, heating the mixture to 65° C., stirring and mixing, fixing the volume, filling the mixture, and sterilizing the mixture to obtain the compound weight loss cream.

[0052] Example 6

[0053] A Chinese medicine composition with weight loss effect is prepared by taking the raw materials in Example 3. The specific preparation method is:

[0054] (a) Add 15 times the amount of water to Prunus mume, Poria cocos, Coix seeds, hawthorn, licorice, lotus leaf, Cassia seed, Panax notoginseng root, bitter melon, tangerine peel, and Yunnan black tea, boil and extract for 2.5 hours, and pass through a 100-mesh sieve to obtain the first extract;

[0055] (b) adding 15 times the amount of water again, boiling and extracting for 2.5 hours, boiling for a total of 4 times, and filtering through a 200-mesh sieve to obtain an extract;

[0056] (c) combining the extracts, concentrating in vacuo to a Brix of ≥20%, standing for 24 h, passing through a 100-mesh sieve, discarding the waste residue, and concentrating the filtrate to obtain an extract;

[0057] (d) adding the obtained extract to drinking water, heating the mixture to 70° C., stirring and mixing, fixing the volume, filling and sterilizing the mixture to obtain the compound weight loss cream.

[0058] Example 7

[0059] In order to better illustrate the technical effect of the present invention, the extract obtained in Example 4 was used to carry out the following experiment.

[0060] 1. Animal Modeling

[0061] According to the Guidelines for Health Food (2023 Edition), 70 SPF SD rats weighing 180-200g, all male, were selected according to the specific conditions of the experiment. 12 rats were randomly selected to be given maintenance feed as the blank group, and the remaining 58 rats were given high-calorie feed for modeling. After 2 weeks of feeding, the rats given high-calorie feed were sorted by weight gain, and the obesity-resistant rats with lower weight gain were eliminated.

[0062] 2. Grouping and Dosing

[0063] The 48 obese-sensitive rats screened were randomly divided into 4 groups according to body weight, namely: model group, 0.06, 0.12, and 0.24 g / kg dosage groups of the composition, 12 rats / group. Every day, the rats in the model group and each dosage group of the Chinese medicine composition continued to be given the same amount of high-calorie model feed (the amount of feed given was based on the principle that most animals had eaten it), and the blank group was given maintenance feed in the same way for 6 weeks. During this period, rats in each dosage group of the Chinese medicine composition were gavaged with different doses of the test samples, and rats in the model group and the blank group were given the same amount of the corresponding solvent, 1 time / d, each time at 10 mL / kg for gavage, for 6 consecutive weeks.

[0064] 3. Index detection

[0065] (1) Weight and Lee's Index

[0066] The animals were weighed once every 3 days. One hour after the last administration, the animals in each group were weighed and anesthetized with isoflurane. After anesthesia, the body length (length from nose tip to anus) of the rats in each group was measured and recorded; Lee's index was calculated based on the body weight and body length. The calculation formula is shown below.

[0067] Lee's Index = Weight 1 / 3 ×10 3 / Body length

[0068] (2) Organ wet weight and fat / body ratio

[0069] After measuring the body length of the rats after anesthesia, cut open the abdomen, collect 5mL of blood from the abdominal aorta with a common vacuum blood collection tube, and then take the animal body fat (fat pads around the testicles and kidneys) and liver, and weigh the body fat and liver. The weight of the organs after weighing is directly compared. Then, according to the body weight and body fat, calculate the fat / body ratio according to the following company.

[0070] Fat / body ratio =

[0071] (3) Serum biochemical indicators

[0072] After anesthesia, 5 mL of blood was collected from the abdominal aorta. After the blood sample was allowed to stand for 2 hours, it was centrifuged at 3500 r / min for 15 minutes at 4°C to obtain serum, which was stored in a -80°C refrigerator. Finally, the levels of TC, TG, HDL-C, and LDL-C in serum were detected according to the operating procedures of each detection kit.

[0073] 4. Statistical analysis of data

[0074] The experimental results are ±SD. Graphpad Prism9.0 statistical software was used for statistical analysis, and P<0.05 was considered statistically significant.

[0075] 5. Experimental Results

[0076] (1) Effect of Chinese herbal medicine combination on body weight of rats

[0077] The experimental results of body weight are shown in Table 1: Compared with the blank group, the body weight of rats in the model group increased significantly from before administration to the end of administration (the sixth week) (P<0.01 or P<0.001), indicating that the model was successfully established. Compared with the model group, the body weight of rats in the 0.06g / kg dose group of the Chinese medicine composition decreased significantly in the fourth and sixth weeks of administration (P<0.05); the body weight of rats in the 0.12 and 0.24g / kg dose groups of the Chinese medicine composition decreased significantly in the second, fourth and sixth weeks of administration (P<0.05 or P<0.01).

[0078] Table 1 Effects of Chinese medicine composition on body weight of obese rat model ( ±SD)

[0079]

[0080] (2) Effect of Chinese herbal medicine combination on Lee's index of rats

[0081] The results of the Lee's index experiment are shown in Table 2: Compared with the blank group, the Lee's index of the model group increased significantly (P<0.01), indicating that the model was successfully established; compared with the model group, the Lee's index of each dose group of the Chinese medicine combination was significantly reduced, which was statistically significant (P<0.05).

[0082] Table 2 Effect of Chinese herbal medicine composition on Lee's index of obese rat model ( ±SD)

[0083]

[0084] (3) Effect of Chinese herbal medicine combination on wet weight of rat organs and fat / body ratio

[0085] The results of the organ wet weight experiment are shown in Table 3: Compared with the blank group, the fat wet weight, liver wet weight, and fat / body ratio of the rats in the model group were significantly increased (P<0.001). Compared with the model group, the liver wet weight of the rats in the 0.06g / kg dose group of the Chinese medicine composition was significantly reduced (P<0.05), but there was no significant effect on the fat wet weight and fat / body ratio (P>0.05); the fat wet weight, liver wet weight, and fat / body ratio of the rats in the 0.12 and 0.24g / kg dose groups of the Chinese medicine composition were significantly reduced (P<0.05 or P<0.01 or P<0.001).

[0086] Table 3 Effects of Chinese medicine combination on wet weight of organs and fat / body ratio in obese rat model ( ±SD)

[0087]

[0088] (4) Effects of Chinese herbal medicine combination on serum biochemical indexes in rats

[0089] The experimental results of TG, TC, HDL-C and LDL-C in serum are shown in Table 4: compared with the blank group, the TG, TC and LDL-C contents in serum of rats in the model group were significantly increased, and the HDL-C content was significantly decreased (P<0.05 or P<0.001); compared with the model group, the TG, TC and LDL-C contents in serum of rats in each dose group of the Chinese medicine combination were significantly decreased, and the HDL-C content was significantly increased (P<0.05 or P<0.01 or P<0.001).

[0090] Table 4 Effects of Chinese medicine composition on serum biochemical indexes of obese rat model ( ±SD)

[0091]

[0092] In summary, the Chinese medicine composition of the present invention can significantly reduce the body weight, Lee's index, fat wet weight, liver wet weight, fat / body ratio, serum total cholesterol, triglyceride, low-density lipoprotein content of obese rats, and can significantly increase the serum high-density lipoprotein content of obese rats, indicating that the Chinese medicine composition of the present invention has a significant weight-loss effect and is a safe, simple to prepare, and excellent weight-loss formula.

[0093] The applicant declares that the present invention uses the above-mentioned embodiments to illustrate a Chinese medicine composition with weight loss effect and its preparation method and application, but the present invention is not limited to the above-mentioned embodiments, that is, it does not mean that the present invention must rely on the above-mentioned embodiments to be implemented. Those skilled in the art should understand that any improvement of the present invention, equivalent replacement of various raw materials of the product of the present invention, addition of auxiliary components, selection of specific methods, etc., all fall within the protection scope and disclosure scope of the present invention.

[0094] The preferred embodiments of the present invention are described in detail above. However, the present invention is not limited to the specific details in the above embodiments. Within the technical concept of the present invention, a variety of simple modifications can be made to the technical solution of the present invention, and these simple modifications all belong to the protection scope of the present invention.

[0095] It should also be noted that the various specific technical features described in the above specific embodiments can be combined in any suitable manner without contradiction. In order to avoid unnecessary repetition, the present invention will not further describe various possible combinations.

Claims

1. A Chinese medicine composition with weight loss effect, characterized in that: The traditional Chinese medicine composition is made of the following raw materials, in parts by weight: 5-10 parts of ginseng, 5-10 parts of tuckahoe, 5-10 parts of coix seeds, 3-9 parts of hawthorn, 1-4 parts of licorice, 1-4 parts of lotus leaves, 1-4 parts of cassia seeds, 0.1-2.0 parts of Panax notoginseng roots, 0.1-2.0 parts of bitter melon, 0.1-2.0 parts of tangerine peel, and 0.01-1.0 parts of Yunnan black tea.

2. A Chinese medicine composition with weight loss efficacy according to claim 1, characterized in that: The Chinese medicine composition is made of the following raw materials in parts by weight: 6-9 parts of ginseng, 6-9 parts of tuckahoe, 6-9 parts of coix seeds, 4-8 parts of hawthorn, 1-3 parts of licorice, 1-3 parts of lotus leaves, 1-3 parts of cassia seeds, 0.1-1.5 parts of Panax notoginseng roots, 0.1-1.5 parts of bitter melon, 0.1-1.5 parts of tangerine peel, and 0.01-0.9 parts of Yunnan black tea.

3. A Chinese medicine composition with weight loss efficacy according to claim 1, characterized in that: The Chinese medicine composition is made of the following raw materials in parts by weight: 7 parts of ginseng, 7 parts of tuckahoe, 7 parts of coix seeds, 7 parts of hawthorn, 2.5 parts of licorice, 2.5 parts of lotus leaves, 2.5 parts of cassia seeds, 0.9 parts of Panax notoginseng roots, 0.8 parts of bitter melon, 0.5 parts of tangerine peel, and 0.15 parts of Yunnan black tea.

4. A Chinese medicine composition with weight loss efficacy according to any one of claims 1 to 3, characterized in that: The Chinese medicine composition is used in preparing functional food or medicine with weight loss effect.

5. A Chinese medicine composition with weight loss efficacy according to any one of claims 1 to 3, characterized in that: The specific steps of the preparation method of the Chinese medicine composition are as follows: (a) adding 8-15 times amount of water to quinquefolius, Poria cocos, coix seed, hawthorn, liquorice, lotus leaf, cassia seed, notoginseng root, bitter melon, tangerine peel, and Yunnan black tea, decocting and extracting for 2-4 times, and sieving to obtain an extract; (b) vacuum concentrating the extract, standing for 12-24 hours, passing through a 100-200 mesh sieve, discarding the waste residue, and concentrating the filtrate to obtain an extract; (c) adding the obtained extract to drinking water, heating the mixture to 50-70° C., stirring and mixing, fixing the volume, filling and sterilizing the mixture to obtain a Chinese medicine composition.

6. A Chinese medicine composition with weight loss efficacy according to any one of claims 1 to 3, characterized in that: The Chinese medicine composition is prepared into ointment, tablet, capsule, oral liquid, granule, pill, powder, suspension or syrup.

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