Sample analysis system and control method thereof

Abstract

The invention is suitable for the field of in-vitro diagnostic equipment, and discloses a sample analysis system and a control method of the sample analysis system. The sample analysis system comprises a sample management device, a sample determination device, a sample container transmission device, a first camera device and a control device, and the sample determination device comprises a sample distribution mechanism and a determination mechanism. The control device is configured to control the sample container transmission device to transmit a first sample container to a first shooting position and control the first shooting device to execute a first shooting action on the first sample container when the first sample container which is loaded with a blood sample and has a clot abnormal phenomenon in the blood sample is placed in the sample management device; and controlling the sample container conveying device to convey a first sample container to the first storage space, wherein the first sample container is not used for measuring the upper-layer liquid loaded in the first sample container after the first shooting action is completed. The present invention can prevent a measurement mechanism from measuring a blood sample having an abnormal clot phenomenon.

Description

Technical Field

[0001] The present invention relates to the field of in vitro diagnostic equipment, and in particular to a sample analysis system and a control method of the sample analysis system. Background Art

[0002] A sample analysis system provided by the related art is used to perform coagulation testing on a blood sample. Before the sample analysis system performs coagulation testing on the blood sample, the blood sample may have abnormal coagulation. If the blood sample has serious coagulation abnormality before the coagulation test, the coagulation test result may only reflect the problem of the blood sample, but cannot reflect the true coagulation function of the patient to whom the blood sample belongs.

[0003] In order to reduce the impact of clots in blood samples on coagulation test results, related technologies propose a scheme for performing the following quality inspection on blood samples before the sample analysis system performs coagulation test on the blood samples: when the sample needle draws the blood sample, the sample suction pressure of the sample needle is monitored by a pressure sensor to determine whether clots are drawn in, thereby determining whether there is any abnormal clotting phenomenon in the blood sample.

[0004] However, the above-mentioned scheme for clot detection of blood samples still has the following shortcomings in specific applications: (1) The above-mentioned scheme for clot detection of blood samples can only obtain the corresponding clot detection results after the blood sample enters the sample measurement device and the blood sample has begun to be drawn, which will cause the blood sample with clot quality problems to still undergo the normal measurement process. This will, on the one hand, lead to waste of reagents, and on the other hand, it is not conducive to improving the efficiency of batch blood sample measurement by the sample analysis system. (2) When the sample needle is inserted into the blood sample to draw the sample, it sometimes contacts the clot and sometimes does not contact the clot. In addition, due to the accuracy limitation of the pressure sensor, sometimes even if the sample needle touches the clot, it may not be able to accurately detect the presence of a clot in the blood sample. Therefore, this pressure detection method has a high probability of missing abnormal clot problems. Summary of the invention

[0005] The first object of the present invention is to provide a sample analysis system, which aims to solve the technical problem in the related art that a blood sample with abnormal clotting phenomenon can normally enter the sample measurement device for coagulation measurement, affecting the overall measurement efficiency of the sample analysis system.

[0006] To achieve the above object, the present invention provides a solution: a sample analysis system, comprising:

[0007] A sample management device, the sample management device is at least used for placing a sample container loaded with a blood sample to achieve the loading of the blood sample;

[0008] A sample measuring device, the sample measuring device comprising a sample dispensing mechanism and a measuring mechanism, the sample dispensing mechanism is used to absorb at least part of the upper layer liquid from the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer liquid, an intermediate layer liquid, and a lower layer liquid, and distribute it to a reaction container, the intermediate layer liquid containing platelets and / or leukocytes; the measuring mechanism is used to measure the test liquid in the reaction container made of at least the absorbed upper layer liquid and a reagent;

[0009] a sample container transporting device, the sample container transporting device being used to transport the sample container loaded with the blood sample from the sample management device to the sample measuring device;

[0010] a first camera device, the first camera device being used to perform a first photographing action on the sample container from obliquely above or obliquely below the middle layer liquid loaded in the sample container before the sample dispensing mechanism absorbs the upper layer liquid from the sample container;

[0011] A control device, the control device being configured to:

[0012] When a first sample container loaded with the blood sample and having abnormal clots in the blood sample is placed in the sample management device, the sample container transfer device is controlled to transfer the first sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position, the first camera device is controlled to perform the first shooting action on the first sample container located at the first shooting position, and the sample container transfer device is controlled to transfer the first sample container after the first shooting action is completed and the upper layer of liquid loaded therein is not measured by the measuring mechanism to the first storage space;

[0013] When a second sample container loaded with the blood sample and having no abnormal clot phenomenon in the blood sample is placed in the sample management device, the sample container transmission device is controlled to transmit the second sample container loaded with the blood sample and after the blood sample is centrifuged and stratified into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position, the first camera device is controlled to perform the first shooting action on the second sample container located at the first shooting position, the sample container transmission device is controlled to transmit the second sample container after completing the first shooting action to the sample measurement device, the sample distribution mechanism is controlled to absorb at least a part of the upper layer of liquid from the second sample container and distribute it to the first reaction container, and the measurement mechanism is controlled to measure the first test liquid made of at least the upper layer of liquid distributed to the first reaction container and a reagent;

[0014] Wherein, the first storage space is located in the sample management device, or is located beside the sample container transmission device, or is located below the sample container transmission device, or is located above the sample container transmission device.

[0015] As an embodiment, the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space includes: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid has not been transported by the sample container transporting device to the sample measuring device to the first storage space;

[0016] Alternatively, the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space includes: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed to the sample measuring device, and controlling the sample container transporting device to transport the first sample container output from the sample measuring device and the upper layer liquid has not been sucked out of it by the sample dispensing mechanism to the first storage space;

[0017] Alternatively, the sample measuring device further includes a reagent dispensing mechanism, and the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space comprises: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least part of the upper layer liquid from the first sample container and distribute it to a second reaction container, and controlling the sample container transporting device to transport the first sample container output from the sample measuring device and before the reagent dispensing mechanism distributes the reagent to the second reaction container to the first storage space;

[0018] Alternatively, the sample measuring device further includes an incubation mechanism, and the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space comprises: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least a portion of the upper layer liquid from the first sample container and distribute it to a second reaction container, and controlling the sample container transporting device to transport the first sample container output from the sample measuring device and without the incubation mechanism incubating the liquid in the second reaction container at least containing the upper layer liquid distributed from the first sample container to the second reaction container to the first storage space;

[0019] Alternatively, the sample measuring device further includes a reagent dispensing mechanism and an incubation mechanism, and the control of the sample container transmission device to transfer the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space includes: controlling the sample container transmission device to transfer the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least a portion of the upper layer liquid from the first sample container and distribute it to a second reaction container, controlling the incubation mechanism to incubate the liquid in the second reaction container that at least contains the upper layer liquid distributed from the first sample container to the second reaction container, controlling the reagent dispensing mechanism to distribute the reagent to the second reaction container, and controlling the sample container transmission device to transfer the first sample container that is output from the sample measuring device and the second liquid to be tested that at least contains the upper layer liquid distributed to the second reaction container and the reagent has not been measured by the measuring mechanism to the first storage space.

[0020] As an embodiment, when a first sample container loaded with the blood sample and having abnormal clotting phenomenon in the blood sample is placed in the sample management device, after controlling the first camera device to perform the first shooting action on the first sample container located at the first shooting position, the control device is further configured to: output prompt information for indicating that the blood sample in the first sample container has abnormal clotting phenomenon;

[0021] Preferably, after the sample container transmission device is controlled to transmit the first sample container to the first storage space after completing the first shooting action and without the upper layer liquid loaded therein being measured by the measuring mechanism, the control device is further configured to: output prompt information for characterizing the presence of abnormal clotting phenomenon in the blood sample in the first sample container.

[0022] As an embodiment, the sample analysis system further includes a first display screen, the first display screen and the sample measuring device are independently arranged, the first display screen is used to display at least the storage information of the blood sample in the sample management device and the information of the blood sample transmitted by the sample container transmission device, and the outputting of the prompt information indicating that the blood sample in the first sample container has a coagulation abnormality includes: controlling the first display screen to display the prompt information indicating that the blood sample in the first sample container has a coagulation abnormality;

[0023] And / or, the sample measuring device further comprises a second display screen, the second display screen is used to display at least the measuring item information of the blood sample in the sample measuring device, and the outputting of the prompt information indicating that the blood sample in the first sample container has an abnormal clotting phenomenon comprises: controlling the second display screen to display the prompt information indicating that the blood sample in the first sample container has an abnormal clotting phenomenon;

[0024] And / or, the outputting of the prompt information for indicating that the blood sample in the first sample container has an abnormal clotting phenomenon includes: transmitting the prompt information for indicating that the blood sample in the first sample container has an abnormal clotting phenomenon to a laboratory information management system that is communicatively connected to the sample analysis system;

[0025] And / or, the sample analysis system also includes an alarm device, the alarm device includes a sound alarm component and / or a light alarm component, and the output is used to indicate that the blood sample in the first sample container has an abnormal clotting phenomenon, including: controlling the alarm device to emit a sound alarm signal and / or a light alarm signal for indicating that the blood sample in the first sample container has an abnormal clotting phenomenon.

[0026] As an embodiment, controlling the sample container transport device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space includes: controlling the sample container transport device to transport the first sample container along a first route to the first storage space;

[0027] The controlling the sample container transport device to transport the second sample container after the first shooting action is completed to the sample measuring device comprises: controlling the sample container transport device to transport the second sample container to the sample measuring device along a second route;

[0028] The first route is at least partially different from the second route.

[0029] As an embodiment, the control of the sample container transmission device to transmit the first sample container after the first shooting action is completed and the upper layer liquid loaded thereon has not been measured by the measuring mechanism to the first storage space includes: based on the image obtained by the first camera device performing the first shooting action on the first sample container located at the first shooting position, controlling the sample container transmission device to transmit the first sample container after the first shooting action is completed and the upper layer liquid loaded thereon has not been measured by the measuring mechanism to the first storage space.

[0030] As an embodiment, according to the image obtained by the first camera device performing the first shooting action on the first sample container located at the first shooting position, controlling the sample container transport device to transport the first sample container after completing the first shooting action and without the upper layer liquid loaded therein being measured by the measuring mechanism to the first storage space includes:

[0031] Obtaining a first target image according to information fed back by the first camera device performing the first shooting action on the first sample container located at the first shooting position;

[0032] When it is determined according to the first target image that the blood sample loaded in the first sample container has an abnormal clot phenomenon, the sample container transmission device is controlled to transmit the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space;

[0033] Preferably, there is a boundary liquid surface or a boundary liquid layer between the intermediate layer liquid and the upper layer liquid; and the first target image at least includes an image showing the boundary liquid surface or the boundary liquid layer in a two-dimensional form and / or a three-dimensional form.

[0034] As an embodiment, determining, based on the first target image, whether the blood sample loaded in the first sample container has abnormal clot phenomenon includes:

[0035] Extracting a target index for characterizing the flatness of the intermediate layer liquid in the first target image;

[0036] comparing the target indicator with a preset indicator;

[0037] If the target index is greater than or equal to the preset index, it is determined that the blood sample loaded in the first sample container has abnormal clotting phenomenon;

[0038] Alternatively, determining, based on the first target image, that the blood sample loaded in the first sample container has an abnormal clot phenomenon includes:

[0039] extracting target features in the first target image;

[0040] comparing the target feature with a preset feature;

[0041] If the similarity between the target feature and the preset feature is greater than or equal to a first preset threshold, it is determined that the blood sample loaded in the first sample container has a clot abnormality;

[0042] Alternatively, determining, based on the first target image, that the blood sample loaded in the first sample container has an abnormal clot phenomenon includes:

[0043] comparing the first target image with a preset image;

[0044] If the similarity between the first target image and the preset image is greater than or equal to a second preset threshold, it is determined that the blood sample loaded in the first sample container has a clot abnormality.

[0045] As an embodiment, after controlling the first camera device to perform the first shooting action on the second sample container located at the first shooting position, and before controlling the measuring mechanism to measure the first test liquid prepared by at least the upper layer liquid and the reagent distributed in the first reaction container, the control device is further configured to:

[0046] Obtaining a first target image according to information fed back by the first camera device performing the first shooting action on the second sample container located at the first shooting position;

[0047] According to the first target image, determining that the blood sample loaded in the second sample container has no abnormal clot phenomenon;

[0048] Preferably, there is a boundary liquid surface or a boundary liquid layer between the intermediate layer liquid and the upper layer liquid; and the first target image at least includes an image showing the boundary liquid surface or the boundary liquid layer in a two-dimensional form and / or a three-dimensional form.

[0049] As an embodiment, the sample analysis system further includes a first reflector, and the first reflector is used to: when the first camera device performs the first shooting action, reflect the image of the sample container to the first camera device; the first camera device performs the first shooting action on the sample container including: the first camera device shoots the image of the sample container in the first reflector toward the first reflector;

[0050] Alternatively, the first camera device captures the image of the sample container from obliquely above or obliquely below the intermediate layer of liquid, directly toward the sample container.

[0051] As an embodiment, the sample analysis system further comprises a second camera device, which is used to perform a second shooting action on the sample container before the sample dispensing mechanism absorbs at least part of the upper layer of liquid from the sample container;

[0052] The control device is also configured to:

[0053] Obtaining a second target image according to information fed back by the second camera device performing the second shooting action;

[0054] According to the second target image, at least one of the following information is obtained: the total liquid volume of the blood sample in the sample container, the hematocrit of the blood sample in the sample container, the hemolysis index of the blood sample in the sample container, the icterus index of the blood sample in the sample container, and the lipemia index of the blood sample in the sample container;

[0055] Preferably, the second target image at least includes an image showing the entire height of one side of the sample container in a two-dimensional and / or three-dimensional form, or at least includes an image showing all of the blood samples in the sample container in a two-dimensional and / or three-dimensional form, or at least includes an image showing the liquid level of the upper liquid layer, the liquid level of the middle liquid layer, and the liquid level of the lower liquid layer in the sample container in a two-dimensional and / or three-dimensional form, or at least includes an image showing all of the upper liquid layer, all of the middle liquid layer, and all of the lower liquid layer in the sample container in a two-dimensional and / or three-dimensional form, or at least includes an image showing at least one side of the bottom, middle part, and top of the sample container in a two-dimensional and / or three-dimensional form;

[0056] The second camera device and the first camera device are two independent camera devices, or the second camera device and the first camera device are the same camera device.

[0057] As an implementation manner, the control device is further configured to:

[0058] When a third sample container loaded with a blood sample and having a total liquid volume less than a first threshold, or a hematocrit of the blood sample greater than a second threshold, or a hematocrit of the blood sample less than a third threshold, or a hemolysis index of the blood sample greater than a fourth threshold, or a icteric index of the blood sample greater than a fifth threshold, or a lipemia index of the blood sample greater than a sixth threshold is placed in the sample management device, the sample container transfer device is controlled to transfer the third sample container loaded with the blood sample and having the blood sample centrifugally separated into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the second shooting position;

[0059] Controlling the second camera device to perform the second shooting action on the third sample container located at the second shooting position;

[0060] Controlling the sample container transport device to transport the third sample container after the second shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the second storage space;

[0061] The second storage space and the first storage space are the same storage space, or the second storage space and the first storage space are two different storage spaces.

[0062] As an embodiment, when the third sample container loaded with the blood sample and having a hematocrit greater than the second threshold value, or having a hematocrit less than the third threshold value, is placed in the sample management device, after controlling the second camera device to perform the second shooting action on the third sample container located at the second shooting position, the control device is further configured to: output prompt information for indicating that the hematocrit of the blood sample in the third sample container is too high or too low;

[0063] Preferably, the control device is further configured to: after the sample container transport device is controlled to transport the third sample container after the second shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the second storage space, output a prompt message for indicating that the hematocrit of the blood sample in the third sample container is too high or too low;

[0064] Preferably, the sample analysis system further comprises a first display screen, which is independently arranged from the sample measuring device, and is at least used to display storage information of the blood sample in the sample management device and information of the blood sample transmitted by the sample container transmission device, and the output is used to indicate prompt information that the hematocrit of the blood sample in the third sample container is too high or too low, comprising: controlling the first display screen to display prompt information that the hematocrit of the blood sample in the third sample container is too high or too low.

[0065] As an embodiment, when the third sample container loaded with a blood sample and the hematocrit of the blood sample is greater than the second threshold, or the hematocrit of the blood sample is less than the third threshold, is placed in the sample management device, after controlling the second camera device to perform the second shooting action on the third sample container located at the second shooting position, the control device is further configured to: output recommended collection amount information for characterizing the blood sample and / or output recommended usage amount information for characterizing the anticoagulant;

[0066] Preferably, the control device is further configured to: after controlling the sample container transport device to transport the third sample container after the second shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the second storage space, output the recommended collection amount information for characterizing the blood sample and / or output the recommended usage amount information for characterizing the anticoagulant;

[0067] Preferably, the output is used to characterize the recommended collection volume information of the blood sample and / or the output is used to characterize the recommended usage information of the anticoagulant, including: controlling the first display screen to display the recommended collection volume information for characterizing the blood sample and / or the recommended usage information for characterizing the anticoagulant.

[0068] As an embodiment, obtaining the total liquid volume of the blood sample in the sample container according to the second target image includes: obtaining the total liquid level of the blood sample in the sample container according to the second target image, and obtaining the total liquid volume of the blood sample in the sample container according to the total liquid level;

[0069] The obtaining of the hematocrit of the blood sample in the sample container according to the second target image comprises: obtaining the total liquid level height of the blood sample in the sample container and the height of the lower layer liquid according to the second target image, and obtaining the hematocrit of the blood sample in the sample container according to the total liquid level height and the height of the lower layer liquid.

[0070] As an embodiment, obtaining the total liquid volume of the blood sample in the sample container according to the total liquid level includes: obtaining the total liquid volume of the blood sample in the sample container according to the total liquid level and a conversion function pre-stored in the sample analysis system or obtained according to a conversion function calibration process, wherein the conversion function is a conversion relationship between the liquid level in the sample container and the volume of the blood sample;

[0071] The step of obtaining the hematocrit of the blood sample in the sample container according to the total liquid level and the height of the lower layer liquid comprises: obtaining the hematocrit of the blood sample in the sample container according to the total liquid level, the height of the lower layer liquid and the conversion function;

[0072] Alternatively, obtaining the total liquid volume of the blood sample in the sample container according to the total liquid level includes: obtaining, according to the type of the sample container, a conversion function that is pre-stored in the sample analysis system or obtained according to a conversion function calibration process and corresponds to the type of the sample container, and obtaining the total liquid volume of the blood sample in the sample container according to the total liquid level and the conversion function, wherein the conversion function is a conversion relationship between the liquid level in the sample container and the volume of the blood sample;

[0073] The step of obtaining the hematocrit of the blood sample in the sample container according to the total liquid level and the height of the lower layer liquid comprises: obtaining the conversion function corresponding to the type of the sample container according to the type of the sample container, and obtaining the hematocrit of the blood sample in the sample container according to the total liquid level, the height of the lower layer liquid and the conversion function;

[0074] Alternatively, obtaining the total liquid volume of the blood sample in the sample container according to the total liquid level may include: obtaining a size parameter of the sample container according to an instruction input by an operator through a human-computer interaction device; obtaining the total liquid volume of the blood sample in the sample container according to the total liquid level and the size parameter;

[0075] The step of obtaining the hematocrit of the blood sample in the sample container according to the total liquid level and the height of the lower layer liquid comprises: obtaining the hematocrit of the blood sample in the sample container according to the total liquid level, the height of the lower layer liquid and the size parameter.

[0076] As an embodiment, there is a boundary liquid surface or a boundary liquid layer between the intermediate layer liquid and the upper layer liquid;

[0077] The first target image at least includes an image showing the interface liquid surface or the interface liquid layer in a two-dimensional form and / or a three-dimensional form;

[0078] The second camera device is used for performing the second shooting action on the sample container along the horizontal direction before the first camera device performs the first shooting action on the sample container, in which the blood sample is loaded and after the blood sample is centrifuged and layered;

[0079] The control device is further configured to: before acquiring the first target image, first control the second camera device to perform the second shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and layered, obtain the height position of the interface liquid surface or the interface liquid layer according to the image captured by the second camera device when performing the second shooting action, and obtain the target height position according to the height position of the interface liquid surface or the interface liquid layer;

[0080] The obtaining of the first target image includes: controlling one of the sample container and the first camera device to move relative to the other and stop at the target height position, controlling the first camera device to perform the first shooting action on the sample container, and obtaining the first target image based on an image captured by the first camera device performing the first shooting action.

[0081] As an embodiment, the sample management device is provided with a loading area, a recovery area and a first abnormal area, the loading area is used for placing the sample container to realize the loading of the sample container, the recovery area is used for placing the sample container whose blood sample measurement result has been determined to be normal after being measured by the sample measuring device to realize the recovery of the sample container, the first abnormal area is used for storing at least the sample container with abnormal code scanning, the sample container whose blood sample measurement result has been determined to be abnormal after being measured by the sample measuring device, and the sample container whose blood sample has abnormal clot phenomenon after being determined to be loaded by the first camera device, and the first storage space is located in the first abnormal area;

[0082] Alternatively, the sample management device is provided with a loading area, a recovery area, a first abnormal area, and a second abnormal area, the loading area is used for placing the sample container to achieve loading of the sample container, the recovery area is used for placing the sample container whose blood sample measurement result has been determined to be normal after being measured by the sample measuring device to achieve recycling of the sample container, the first abnormal area is used for storing the sample container whose code scanning is abnormal and the sample container whose blood sample measurement result has been determined to be abnormal after being measured by the sample measuring device, the second abnormal area is used for storing the sample container whose blood sample has been determined to have abnormal clot phenomenon after being photographed by the first camera device, and the first storage space is located in the second abnormal area;

[0083] Alternatively, the sample management device is provided with a loading area, a recovery area, a first abnormal area, a second abnormal area and a third abnormal area, the loading area is used for placing the sample container to realize the loading of the sample container, the recovery area is used for placing the sample container that has been determined by the sample measuring device to have a normal measurement result of the blood sample loaded therein to realize the recovery of the sample container, the first abnormal area is used for storing the sample container with abnormal code scanning, the second abnormal area is used for storing the sample container with abnormal clot phenomenon of the blood sample loaded therein determined by the first camera device taking an image, the third abnormal area is used for placing the sample container with abnormal blood sample measurement result of the blood sample loaded therein determined by the sample measuring device, and the first storage space is located in the second abnormal area;

[0084] Alternatively, the sample management device is provided with a loading area, a recovery area and a first abnormal area, the loading area is used for placing the sample container to achieve loading of the sample container, the recovery area is used for placing the sample container that has been measured by the sample measuring device and the measurement result of the blood sample loaded therein is determined to be normal to achieve recovery of the sample container, the first abnormal area is used at least for storing the sample container with abnormal code scanning and the sample container that has been measured by the sample measuring device and the measurement result of the blood sample loaded therein is determined to be abnormal, the sample analysis system also includes a recovery container, the recovery container is located outside the sample management device, and the recovery container is located beside, below or above the sample container transmission device, the recovery container is used for placing the sample container that has been determined by the first camera device to have abnormal clot phenomenon in the blood sample loaded therein, and the first storage space is located in the recovery container.

[0085] As an embodiment, the sample container transmission device includes a conveying track, a first sample container scheduling mechanism and a sample container transfer device, the conveying track is used to convey a sample seat having a single first container position, and the first container position is used to place a single sample container;

[0086] The first sample scheduling mechanism is used to schedule the sample container placed in the sample management device and loaded with the blood sample to the sample seat located on the conveying track;

[0087] The sample container transfer device comprises a sample seat scheduling mechanism, a second sample container scheduling mechanism and a sample rack scheduling mechanism, wherein the sample seat scheduling mechanism is at least used to transport the sample seat transported by the transport track to the sample container transfer device to a rack position, and the second sample container scheduling mechanism is used to schedule the sample container on the sample seat at the rack position to a sample rack provided by the sample rack scheduling mechanism, wherein the sample rack has at least two second container positions, each of which is used to place a single sample container; the sample rack scheduling mechanism is used to schedule the sample rack loaded with the sample container and the blood sample in the sample container to the sample measurement device;

[0088] Wherein, the first shooting position is located in the sample container transfer device, the first shooting position is set on the path of the sample container transfer device to transfer the sample container and is located between the conveying track and the sample measurement device, and the first camera device is used to perform the first shooting action on the sample container transferred from the sample container transfer device to the first shooting position;

[0089] Alternatively, the first shooting position is located on the conveying track, the first shooting position is set on the path of the conveying track for conveying the sample container and is located between the first sample scheduling mechanism and the sample container transfer device, and the first camera device is used to perform the first shooting action on the sample container conveyed by the conveying track to the first shooting position;

[0090] Alternatively, the first shooting position is located in the sample measuring device, the first shooting position is set on the path of the sample measuring device for conveying the sample container and is located before the sample suction position of the sample dispensing mechanism, and the first camera device is used to perform the first shooting action on the sample container conveyed by the sample measuring device to the first shooting position.

[0091] As an embodiment, the sample analysis system further comprises a centrifugal device, which is used to centrifuge the sample container loaded with the blood sample so that the blood sample is centrifugally layered into the upper layer liquid, the middle layer liquid, and the lower layer liquid;

[0092] The sample management device is used for placing the sample container loaded with the blood sample and not subjected to the centrifugation operation to realize the loading of the uncentrifuged blood sample, and for placing the sample container loaded with the blood sample and subjected to the centrifugation operation to realize the loading of the centrifuged blood sample;

[0093] The sample container transfer device is at least used to transfer the sample container output from the sample management device and loaded with the uncentrifuged blood sample to the centrifuge device for centrifugation, to transfer the sample container output from the centrifuge device and loaded with the centrifuged blood sample to the sample measurement device, and to transfer the sample container output from the sample management device and loaded with the centrifuged blood sample to the sample measurement device;

[0094] Wherein, the first photographing position is provided on the path where the sample container transporting device transports the sample container from the sample management device to the sample measuring device and is located between the centrifugal device and the sample measuring device, and the first camera device is used to perform the first photographing action on the sample container transported to the first photographing position by the sample container transporting device;

[0095] Alternatively, the first shooting position is located in the sample measuring device, the first shooting position is set on the path of the sample measuring device for conveying the sample container and is located before the sample suction position of the sample dispensing mechanism, and the first camera device is used to perform the first shooting action on the sample container conveyed by the sample measuring device to the first shooting position.

[0096] A second object of the present invention is to provide a sample analysis system, the sample analysis system comprising:

[0097] A sample management device, the sample management device is at least used for placing a sample container loaded with a blood sample to achieve the loading of the blood sample;

[0098] A sample measuring device, the sample measuring device comprising a sample dispensing mechanism and a measuring mechanism, the sample dispensing mechanism is used to absorb at least part of the upper layer liquid from the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer liquid, an intermediate layer liquid, and a lower layer liquid, and distribute it to a reaction container, the intermediate layer liquid containing platelets and / or leukocytes; the measuring mechanism is used to measure the test liquid in the reaction container made of at least the absorbed upper layer liquid and a reagent;

[0099] a sample container transporting device, the sample container transporting device being used to transport the sample container loaded with the blood sample from the sample management device to the sample measuring device;

[0100] a first camera device, the first camera device being used to perform a first photographing action on the sample container from obliquely above or obliquely below the middle layer liquid loaded in the sample container before the sample dispensing mechanism absorbs the upper layer liquid from the sample container;

[0101] A control device, the control device being configured to:

[0102] When a first sample container loaded with the blood sample and having abnormal clots in the blood sample is placed in the sample management device, the sample container transport device is controlled to transport the first sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to a first shooting position, the first camera device is controlled to perform the first shooting action on the first sample container located at the first shooting position, and the sample container transport device is controlled to transport the first sample container after the first shooting action is completed and the upper layer of liquid loaded therein is not measured by the measuring mechanism along the first route to the first storage space;

[0103] When a second sample container loaded with the blood sample and having no abnormal clot phenomenon in the blood sample is placed in the sample management device, the sample container transmission device is controlled to transmit the second sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position, the first camera device is controlled to perform the first shooting action on the second sample container located at the first shooting position, the sample container transmission device is controlled to transmit the second sample container after the first shooting action is completed to the sample measurement device along a second route, the sample distribution mechanism is controlled to absorb at least part of the upper layer of liquid from the second sample container and distribute it to the first reaction container, and the measurement mechanism is controlled to measure the first test liquid made of at least the upper layer of liquid distributed to the first reaction container and a reagent;

[0104] The first route is at least partially different from the second route.

[0105] As an embodiment, when a first sample container loaded with the blood sample and having abnormal clotting phenomenon in the blood sample is placed in the sample management device, after controlling the first camera device to perform the first shooting action on the first sample container located at the first shooting position, the control device is further configured to: output prompt information for indicating that the blood sample in the first sample container has abnormal clotting phenomenon;

[0106] Preferably, after the sample container transmission device is controlled to complete the first shooting action and transmits the first sample container along the first route to the first storage space without the upper liquid loaded therein being measured by the measuring mechanism, the control device is further configured to: output prompt information for characterizing the presence of abnormal clotting phenomenon in the blood sample in the first sample container.

[0107] As an embodiment, the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded thereon has not been measured by the measuring mechanism along the first route to the first storage space comprises: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded thereon has not been measured by the measuring mechanism along the first route to the first storage space according to the first target image obtained by the first camera device performing the first shooting action on the first sample container located at the first shooting position;

[0108] Wherein, there is a boundary liquid surface or boundary liquid layer between the intermediate layer liquid and the upper layer liquid;

[0109] The first target image at least includes an image showing the interface liquid surface or the interface liquid layer in a two-dimensional form and / or a three-dimensional form.

[0110] A third object of the present invention is to provide a sample analysis system, the sample analysis system comprising:

[0111] A sample management device, the sample management device is at least used for placing a sample container loaded with a blood sample to achieve the loading of the blood sample;

[0112] A sample measuring device, the sample measuring device comprising a sample dispensing mechanism and a measuring mechanism, the sample dispensing mechanism is used to absorb at least part of the upper layer liquid from the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer liquid, an intermediate layer liquid, and a lower layer liquid, and distribute it to a reaction container, the intermediate layer liquid containing platelets and / or leukocytes; the measuring mechanism is used to measure the test liquid in the reaction container made of at least the absorbed upper layer liquid and a reagent;

[0113] a sample container transporting device, the sample container transporting device being used to transport the sample container loaded with the blood sample from the sample management device to the sample measuring device;

[0114] a first camera device, the first camera device being used to perform a first photographing action on the sample container from obliquely above or obliquely below the middle layer liquid loaded in the sample container before the sample dispensing mechanism absorbs the upper layer liquid from the sample container;

[0115] A control device, the control device being configured to:

[0116] When a first sample container loaded with the blood sample and having abnormal clotting phenomenon in the blood sample is placed in the sample management device, the sample container transmission device is controlled to transmit the first sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer liquid, a middle layer liquid, and a lower layer liquid to a first shooting position, the first camera device is controlled to perform the first shooting action on the first sample container located at the first shooting position, the sample container transmission device is controlled to transmit the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to a first storage space, and prompt information for indicating that the blood sample in the first sample container has abnormal clotting phenomenon is output;

[0117] When a second sample container loaded with the blood sample and having no abnormal clot phenomenon in the blood sample is placed in the sample management device, the sample container transmission device is controlled to transmit the second sample container loaded with the blood sample and after the blood sample is centrifuged and stratified into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position, the first camera device is controlled to perform the first shooting action on the second sample container located at the first shooting position, the sample container transmission device is controlled to transmit the second sample container after completing the first shooting action to the sample measurement device, the sample distribution mechanism is controlled to absorb at least a part of the upper layer of liquid from the second sample container and distribute it to the first reaction container, and the measurement mechanism is controlled to measure a first test liquid made of at least the upper layer of liquid distributed to the first reaction container and a reagent.

[0118] As an embodiment, the sample analysis system further includes a first display screen, the first display screen and the sample measuring device are independently arranged, the first display screen is used to display at least the storage information of the blood sample in the sample management device and the information of the blood sample transmitted by the sample container transmission device, and the outputting of the prompt information indicating that the blood sample in the first sample container has a coagulation abnormality includes: controlling the first display screen to display the prompt information indicating that the blood sample in the first sample container has a coagulation abnormality;

[0119] And / or, the sample measuring device further comprises a second display screen, the second display screen is used to display at least the measuring item information of the blood sample in the sample measuring device, and the outputting of the prompt information indicating that the blood sample in the first sample container has an abnormal clotting phenomenon comprises: controlling the second display screen to display the prompt information indicating that the blood sample in the first sample container has an abnormal clotting phenomenon;

[0120] And / or, the outputting of the prompt information for indicating that the blood sample in the first sample container has an abnormal clotting phenomenon includes: transmitting the prompt information for indicating that the blood sample in the first sample container has an abnormal clotting phenomenon to a laboratory information management system that is communicatively connected to the sample analysis system;

[0121] And / or, the sample analysis system also includes an alarm device, the alarm device includes a sound alarm component and / or a light alarm component, and the output is used to indicate that the blood sample in the first sample container has an abnormal clotting phenomenon, including: controlling the alarm device to emit a sound alarm signal and / or a light alarm signal for indicating that the blood sample in the first sample container has an abnormal clotting phenomenon.

[0122] As an embodiment, the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded thereon has not been measured by the measuring mechanism to the first storage space comprises: according to a first target image obtained by the first camera device performing the first shooting action on the first sample container located at the first shooting position, controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded thereon has not been measured by the measuring mechanism to the first storage space;

[0123] Wherein, there is a boundary liquid surface or boundary liquid layer between the intermediate layer liquid and the upper layer liquid;

[0124] The first target image at least includes an image showing the interface liquid surface or the interface liquid layer in a two-dimensional form and / or a three-dimensional form.

[0125] A fourth object of the present invention is to provide a control method for a sample analysis system, the control method comprising:

[0126] Controlling the sample container transmission device to transmit the sample container loaded with the blood sample after the blood sample is centrifuged and separated into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position;

[0127] Controlling the first camera device to perform a first shooting action on the sample container located at the first shooting position to obtain a first target image;

[0128] determining, according to the first target image, whether the blood sample loaded in the sample container has abnormal clot phenomenon;

[0129] If it is determined according to the first target image that the blood sample loaded in the sample container has an abnormal clot phenomenon, the sample container transmission device is controlled to transmit the sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism of the sample measuring device to the first storage space;

[0130] If it is determined according to the first target image that the blood sample loaded in the sample container has no abnormal clot phenomenon, then the sample container transmission device is controlled to transmit the sample container after the first shooting action to the sample measurement device, the sample distribution mechanism of the sample measurement device is controlled to absorb at least part of the upper layer liquid from the sample container and distribute it to a first reaction container, and the measurement mechanism is controlled to measure a first test liquid made of at least the upper layer liquid distributed to the first reaction container and a reagent;

[0131] Wherein, there is a boundary liquid surface or boundary liquid layer between the intermediate layer liquid and the upper layer liquid;

[0132] The first target image at least includes an image showing the interface liquid surface or the interface liquid layer in a two-dimensional form and / or a three-dimensional form.

[0133] As an embodiment, after determining that the blood sample loaded in the sample container has abnormal clotting phenomenon, the control method further includes: outputting prompt information for indicating that the blood sample in the sample container has abnormal clotting phenomenon;

[0134] Preferably, after controlling the sample container transmission device to transmit the sample container to the first storage space after completing the first shooting action and without the upper layer liquid loaded therein being measured by the measuring mechanism of the sample measuring device, the control method further includes: outputting prompt information for characterizing the presence of abnormal clotting phenomenon in the blood sample in the sample container.

[0135] As an embodiment, before controlling the sample container transfer device to transfer the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into the upper layer liquid, the middle layer liquid, and the lower layer liquid to the first shooting position, the control method further includes:

[0136] Controlling the sample container transfer device to transfer the sample container loaded with the blood sample after the blood sample is centrifuged and separated into the upper layer liquid, the middle layer liquid, and the lower layer liquid to the second shooting position;

[0137] Controlling the second camera device to perform a second shooting action on the sample container located at the second shooting position to obtain a second target image;

[0138] According to the second target image, at least one of the following information is obtained: the total liquid volume of the blood sample in the sample container, the hematocrit of the blood sample in the sample container, the hemolysis index of the blood sample in the sample container, the icterus index of the blood sample in the sample container, and the lipemia index of the blood sample in the sample container;

[0139] When it is determined according to the second target image that the blood sample satisfies at least one of the following conditions: the total liquid volume of the blood sample is less than a first threshold, or the hematocrit of the blood sample is greater than a second threshold, or the hematocrit of the blood sample is less than a third threshold, or the hemolytic index of the blood sample is greater than a fourth threshold, or the icteric index of the blood sample is greater than a fifth threshold, or the lipemia index of the blood sample is greater than a sixth threshold, the sample container transport device is controlled to transport the sample container after the second shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism of the sample measuring device to the second storage space;

[0140] The second storage space and the first storage space are the same storage space, or the second storage space and the first storage space are two different storage spaces.

[0141] The sample analysis system and control method provided by the present invention use a first camera device to photograph the centrifuged blood sample before blood sample aspiration. When a blood sample with abnormal clotting phenomenon enters the sample analysis system, the control device controls the sample container transmission device to transmit the blood sample that has been photographed by the first camera device and has not been measured by the measuring mechanism to the first storage space, thereby effectively preventing the measuring mechanism from measuring the blood sample with abnormal clotting phenomenon, at least saving the time for the measuring mechanism to measure the blood sample with abnormal clotting phenomenon, and thus helping to improve the sample measurement efficiency of the sample analysis system. BRIEF DESCRIPTION OF THE DRAWINGS

[0142] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the structures shown in these drawings without paying creative work.

[0143] Figure 1 This is a schematic diagram of the distribution of the camera device provided by an embodiment of the present invention in a sample analysis device;

[0144] Figure 2is another schematic diagram of the distribution of the camera device in the sample analysis device provided by the embodiment of the present invention;

[0145] Figure 3 is another schematic diagram of the distribution of the camera device in the sample analysis device provided by the embodiment of the present invention;

[0146] Figure 4 is a schematic diagram of a first camera device provided by an embodiment of the present invention indirectly capturing an image of a sample container through a first reflecting mirror;

[0147] Figure 5 is a schematic diagram of a first camera device directly photographing a sample image provided by an embodiment of the present invention;

[0148] Figure 6 is a schematic diagram of a second camera device provided by an embodiment of the present invention indirectly capturing an image of a sample container through a second reflecting mirror;

[0149] Figure 7 is a schematic diagram of a second camera device directly capturing an image of a sample container provided by an embodiment of the present invention;

[0150] Figure 8 is a display schematic diagram of a first target image and a second target image provided by an embodiment of the present invention;

[0151] Fig. 9 A schematic structural diagram of a sample assay device provided by an embodiment of the present invention.

[0152] Description of the accompanying drawings: 10, sample analysis system; 100, sample management device; 200, sample measurement device; 210, sample suction channel; 220, sample distribution mechanism; 230, measurement mechanism; 240, incubation mechanism; 250, reagent distribution mechanism; 251, mixed reagent dispensing component; 252, trigger reagent dispensing component; 260, reagent tray; 270, reaction container supply mechanism; 280, reaction container transport mechanism; 300, sample container transmission device; 310, conveying track; 320, first sample container scheduling Mechanism; 330, sample container transfer device; 400, first camera device; 500, control device; 600, first reflector; 700, second camera device; 800, first fill light component; 900, centrifugal device; 101, first display screen; 1011, first target image; 1012, second target image; 102, second reflector; 103, second fill light component; 20, sample container; 30, blood sample; 31, upper layer liquid; 32, middle layer liquid; 321, interface liquid surface; 33, lower layer liquid. DETAILED DESCRIPTION

[0153] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0154] The sample analysis system provided in the embodiment of the present application is applicable to an analysis system in which a camera device is used to photograph a sample container and the object to be tested includes at least a blood sample collected from a human or an animal. The blood sample determination by the sample analysis system includes but is not limited to coagulation detection items.

[0155] Prior to this application, the erroneous coagulation test results of some blood samples were caused by the quality of the blood samples before the coagulation test. Before the sample analysis system performs a coagulation test on the blood sample, the blood sample may have at least one of the following quality problems: the HIL of the blood sample (HIL includes the hemolysis index H, the icterus index I, and the lipemia index L) exceeds the anti-interference ability of the test item; the total liquid volume of the blood sample is less than the liquid volume threshold; the HCT (hematocrit) of the blood sample is greater than the first hematocrit threshold; the HCT of the blood sample is less than the second hematocrit threshold; there is an abnormal clot in the blood sample. If there are serious quality problems with the blood sample before the coagulation test, the coagulation test results obtained may only reflect the problems of the blood sample, but cannot reflect the true coagulation function of the patient to whom the blood sample belongs.

[0156] Therefore, it is very important to test the quality of blood samples before coagulation testing. The quality test of blood samples before coagulation testing includes but is not limited to: HIL test (i.e. hemolysis, jaundice, lipemia test), total fluid volume test, HCT (i.e. hematocrit or hematocrit test), and clot test. Among them, the impact of HIL on the coagulation test results is mainly reflected in: if the anti-interference ability of the coagulation test item is exceeded, the coagulation test results may be inaccurate. For the liquid volume and HCT of blood samples, there are clear provisions in the "Ws / T359-2011 Guidelines for the Collection and Processing of Blood Specimens for Plasma Coagulation Experiments" and CLSI "H21-A5": It is required that the liquid volume of blood samples used for coagulation testing shall not be less than the preset threshold (for example, the difference between the total liquid volume of the collected blood sample and the labeled amount is greater than 10%); if the hematocrit of the blood sample is greater than or equal to 55%, or the hematocrit of the blood sample is less than or equal to 20%, the proportion of the anticoagulant needs to be adjusted. The influence of abnormal clotting in blood samples on the coagulation test results includes two aspects: on the one hand, the sample needle touches the clot when drawing the blood sample, resulting in inaccurate sample amount; on the other hand, as long as there is a clot in the blood sample, it means that the blood sample has started the coagulation process, resulting in the consumption of coagulation factors. At this time, even if the sample needle does not touch the clot and the sample amount is accurate, it will cause abnormal coagulation test results. Although this abnormality reflects the coagulation state of the blood sample, it cannot accurately reflect the patient's coagulation parameters.

[0157] In a related technology prior to the present application, the HIL detection method is: by measuring the absorbance at different wavelengths by sampling, the HIL test result of the blood sample is obtained, that is, the jaundice, hemolysis, and lipemia test results of the blood sample are obtained, and then whether the blood sample has jaundice, hemolysis, and lipemia, or the level, concentration, and other information of jaundice, hemolysis, and lipemia are displayed.

[0158] In a related art before this application, the detection method of the total liquid volume of the blood sample and the detection method of whether the blood sample has abnormal clot phenomenon are: through the sample needle aspiration detection, confirm the liquid level of the blood sample to determine whether the total liquid volume of the blood sample is sufficient, and confirm whether there is abnormal clot phenomenon according to the pressure of the aspiration. Among them, the specific method of liquid volume detection is: when the sample needle aspirates the blood sample, the liquid level of the blood sample is obtained through the liquid level detection function of the sample needle, and then the total liquid volume of the blood sample is obtained. The specific method of clot detection is: when the sample needle aspirates the blood sample, by monitoring the aspiration pressure of the sample needle, it is determined whether a clot is aspirated, thereby determining whether the blood sample has abnormal clot phenomenon. In this related art, the clot detection scheme and the liquid volume detection scheme are to obtain the corresponding clot detection results and liquid volume detection results after the blood sample enters the sample measurement device and starts to aspirate the blood sample, which will result in the normal measurement process for blood samples with clot quality problems and insufficient liquid volume, which will lead to a waste of reagents and is not conducive to the improvement of the efficiency of batch blood sample measurement by the sample analysis system.

[0159] In a related technology prior to the present application, one way for a coagulation detection device to obtain HCT test results is to obtain the HCT test results of the same patient measured by a hematology analyzer (also known as a blood cell analyzer) on a LIS system (i.e., a laboratory information management system).

[0160] like Figures 1 to 9 As shown, a first aspect of an embodiment of the present invention provides a sample analysis system 10, which includes a sample management device 100, a sample measurement device 200, and a sample container transmission device 300. The sample management device 100 is at least used for placing a sample container 20 loaded with a blood sample 30 to achieve the loading of the blood sample 30. The sample measurement device 200 is used to absorb at least a portion of the blood sample 30 from the sample container 20 loaded with the blood sample 30 for measurement. The sample container transmission device 300 is used to transfer the sample container 20 loaded with the blood sample 30 from the sample management device 100 to the sample measurement device 200. The sample management device 100 can be used to achieve the loading function of the blood sample 30, and the sample container 20 loaded with the blood sample 30 can be placed in the sample management device 100 by an operator or an operating robot. The sample container transmission device 300 is used to achieve the transmission function of the blood sample 30. The sample measurement device 200 is used to perform the measurement items of the blood sample 30.

[0161] As an embodiment, the sample measuring device 200 is used to measure the centrifuged blood sample 30, that is, the sample measuring device 200 is used to draw at least a portion of the centrifuged blood sample 30 from the sample container 20 loaded with the blood sample 30 and the blood sample 30 after centrifugation and distribute it to the reaction container for reaction and measurement.

[0162] As an embodiment, the sample measuring device 200 is used to absorb at least part of the upper layer liquid 31 from the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and separated into the upper layer liquid 31, the middle layer liquid 32, and the lower layer liquid 33, and distribute it to the reaction container for measurement, that is, the sample measuring device 200 is used to measure the upper layer liquid 31 in the centrifuged blood sample 30. The middle layer liquid 32 contains at least platelets and / or white blood cells. The middle layer liquid 32 is also called the buffy coat layer, the upper layer liquid 31 is plasma or serum, and the lower layer liquid 33 is red blood cells. The blood sample 30 collected from the human body or animal and stored in the sample container 20 is a whole blood sample. In this embodiment, the sample measuring device 200 is used to perform measurement items on the upper layer liquid 31 obtained after the blood sample 30 is centrifuged. Of course, in specific applications, as an alternative implementation, other measuring devices may be provided in the sample analysis system 10 for performing measurement items on the middle layer liquid and / or the lower layer liquid 33; or, as another alternative implementation, other measuring devices may be provided in the sample analysis system 10 for performing measurement items on the uncentrifuged blood sample 30 (i.e., the whole blood sample).

[0163] As an embodiment, the sample measuring device 200 includes a sample distribution mechanism 220 and a measuring mechanism 230. The sample distribution mechanism 220 is used to absorb at least a portion of the upper layer liquid 31 from the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and stratified into an upper layer liquid 31, a middle layer liquid 32, and a lower layer liquid 33, and distribute it to the reaction container, wherein the middle layer liquid 32 contains platelets and / or leukocytes; the measuring mechanism 230 is used to measure the test liquid in the reaction container made of at least the absorbed upper layer liquid 31 and the reagent.

[0164] As an embodiment, the sample analysis system 10 further includes a first camera device 400, which is used to perform a first photographing action on the sample container 20 before the sample dispensing mechanism 220 absorbs the upper layer of liquid 31 from the sample container 20. Specifically, before the sample measuring device 200 absorbs the upper layer of liquid 31 from the sample container 20, the first camera device 400 photographs the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and stratified into the upper layer of liquid 31, the middle layer of liquid 32, and the lower layer of liquid 33. In this embodiment, the first camera device 400 is mainly used to photograph the sample container 20 after centrifugation and before the sample is absorbed, so as to obtain an image of the blood sample 30 before the sample is absorbed, so as to facilitate the quality inspection of the blood sample 30 according to the image and facilitate the operator to review the quality information of the blood sample 30.

[0165] As an embodiment, the first camera device 400 is used to perform a first photographing action on the sample container 20 from the oblique upper or lower side of the intermediate layer liquid 32 loaded in the sample container 20 before the sample dispensing mechanism 220 sucks the upper layer liquid 31 from the sample container 20. In this embodiment, the first camera device 400 photographs the image of the sample container 20 from the oblique upper or lower side of the intermediate layer liquid 32, which is conducive to photographing the liquid surface image of the intermediate layer liquid 32, that is, the two-dimensional liquid surface image and / or the three-dimensional liquid surface image of the white film layer.

[0166] As an embodiment, the sample analysis system 10 further includes a control device 500, which is configured to: when a first sample container 20 loaded with a blood sample 30 and having a clot abnormality is placed in the sample management device 100, control the sample container transfer device 300 to transfer the first sample container 20 loaded with a blood sample 30 and having the blood sample 30 separated into an upper layer liquid 31, an intermediate layer liquid 32, and a lower layer liquid 33 after centrifugation to the first shooting position, control the first camera device 400 to perform a first shooting action on the first sample container 20 located at the first shooting position, and control the sample container transfer device 300 to transfer the first sample container 20 after the first shooting action is completed and the upper layer liquid 31 loaded therein has not been measured by the measuring mechanism 230 to the first storage space. The blood sample 30 having a clot abnormality includes at least one of the following situations: there is a clot in the blood sample 30 and the clot meets the first preset condition, and the degree of coagulation of the blood sample 30 meets the second preset condition. The first storage space is used to recycle the sample container 20 having a clot abnormality. In the present embodiment, when a blood sample 30 with abnormal clotting phenomenon enters the sample analysis system 10, the control device 500 controls the sample container transmission device 300 to transmit the blood sample 30 that has been photographed by the first camera device 400 but has not been measured by the measuring mechanism 230 to the first storage space, that is, the blood sample 30 with abnormal clotting phenomenon will not be sent to the measuring mechanism 230, thereby effectively preventing the measuring mechanism 230 from measuring the blood sample 30 with abnormal clotting phenomenon, that is, the blood sample 30 with abnormal clotting phenomenon is intercepted, at least the time for the measuring mechanism 230 to measure the blood sample 30 with abnormal clotting phenomenon is saved, and thus it is beneficial to improve the sample measurement efficiency of the sample analysis system 10.

[0167] As an embodiment, the control device 500 is further configured to: when the second sample container 20 loaded with the blood sample 30 and having no abnormal clot phenomenon in the blood sample 30 is placed in the sample management device 100, control the sample container transfer device 300 to transfer the second sample container 20 loaded with the blood sample 30 and having the blood sample 30 separated into the upper layer liquid 31, the middle layer liquid 32, and the lower layer liquid 33 after centrifugation to the first shooting position, control the first camera device 400 to perform a first shooting action on the second sample container 20 located at the first shooting position, control the sample container transfer device 300 to transfer the second sample container 20 after completing the first shooting action to the sample measurement device 200, control the sample distribution mechanism 220 to absorb at least part of the upper layer liquid 31 from the second sample container 20 and distribute it to the first reaction container, and control the measurement mechanism 230 to measure the first test liquid prepared by at least the upper layer liquid 31 distributed to the first reaction container and the reagent. The second sample container 20 and the first sample container 20 are two different sample containers 20, not the same sample container 20. The blood sample 30 without abnormal clotting phenomenon includes at least one of the following situations: there is no clot in the blood sample 30, there is clot in the blood sample 30 but the clot does not meet the first preset condition, and the degree of coagulation of the blood sample 30 does not meet the second preset condition. In this embodiment, when the blood sample 30 without abnormal clotting phenomenon enters the sample analysis system 10, the control device 500 controls the sample container transmission device 300 to transmit the second sample container 20 after completing the first shooting action to the sample measurement device 200, so that the sample distribution mechanism 220 and the measurement mechanism 230 normally aspirate and measure the blood sample 30 in the second sample container 20.

[0168] As an embodiment, the first storage space is located in the sample management device 100. In this embodiment, the first storage space for recovering the sample container 20 with abnormal clotting phenomenon is set in the sample management device 100, and the blood sample 30 with abnormal clotting phenomenon can be returned to the sample management device 100 through the sample transmission device, so that the structure of the sample analysis system 10 can be used to realize the recovery function of the sample container 20 with abnormal clotting phenomenon, without the need to set up other components to recover the sample container 20 with abnormal clotting phenomenon, which can help simplify the structure of the sample analysis system 10 while meeting the recovery function of the sample container 20 with abnormal clotting phenomenon. Of course, in specific applications, the setting method of the first storage space is not limited to this. For example, as an alternative embodiment, the first storage space is located beside the sample container transmission device 300, that is, the first storage space is located on the side or horizontal side of the sample transmission device, and the blood sample 30 with abnormal clotting phenomenon can be transferred to the first storage space by track transmission or manipulator. Alternatively, as another alternative embodiment, the first storage space is located below the sample container transport device 300, and the sample container transport device 300 is provided with a recovery port connected to the first storage space, and the blood sample 30 with abnormal clotting phenomenon can be transferred to the recovery port by rail transport or robot. Alternatively, as another alternative embodiment, the first storage space is located above the sample container transport device 300, and the blood sample 30 with abnormal clotting phenomenon can be transferred to the first storage space by robot.

[0169] As an embodiment, the above-mentioned controlling the sample container transporting device 300 to transport the first sample container 20 after the first shooting action is completed and the upper layer liquid 31 loaded therein has not been measured by the measuring mechanism 230 to the first storage space includes: according to the image obtained by the first camera device 400 performing the first shooting action on the first sample container 20 located at the first shooting position, controlling the sample container transporting device 300 to transport the first sample container 20 after the first shooting action is completed and the upper layer liquid 31 loaded therein has not been measured by the measuring mechanism 230 to the first storage space. In this embodiment, the control device 500 controls the sample container transporting device 300 to transport the blood sample 30 with abnormal clot phenomenon to the first storage space according to the image of the sample container 20 captured by the first camera device 400, that is, the image of the sample container 20 captured by the first camera device 400 is used as the basis for the control device 500 to determine whether to control the sample container transporting device 300 to transfer the blood sample 30 to the first storage space.

[0170] As an embodiment, the above-mentioned control of the sample container transmission device 300 to transmit the first sample container 20 located at the first shooting position after the first shooting action is completed and the upper layer liquid 31 thereof has not been measured by the measuring mechanism 230 to the first storage space according to the image obtained by the first camera device 400 performing the first shooting action on the first sample container 20 located at the first shooting position includes: obtaining the first target image 1011 according to the information fed back by the first camera device 400 performing the first shooting action on the first sample container 20 located at the first shooting position; when it is determined according to the first target image 1011 that the blood sample 30 loaded in the first sample container 20 has an abnormal clot phenomenon, the sample container transmission device 300 is controlled to transmit the first sample container 20 located at the first shooting position after the first shooting action is completed and the upper layer liquid 31 thereof has not been measured by the measuring mechanism 230 to the first storage space. In this embodiment, the control device 500 can analyze the first target image 1011 obtained by the first camera device 400 photographing the sample container 20 to determine whether the blood sample 30 loaded in the sample container 20 has an abnormal clot phenomenon. When it is determined that the blood sample 30 loaded in the first sample container 20 has an abnormal clot phenomenon according to the first target image 1011, the sample container transmission device 300 is controlled to transmit the blood sample 30 with the abnormal clot phenomenon to the first storage space. That is, the node at which the control device 500 controls the sample container transmission device 300 to transmit the blood sample 30 with the abnormal clot phenomenon to the first storage space is located after it is determined that the blood sample 30 loaded in the first sample container 20 has an abnormal clot phenomenon according to the first target image 1011.

[0171] As an embodiment, after controlling the first camera device 400 to perform the first shooting action on the second sample container 20 located at the first shooting position, and before controlling the measuring mechanism 230 to measure the first test liquid made of at least the upper layer liquid 31 and the reagent distributed in the first reaction container, the control device 500 is further configured to: obtain the first target image 1011 according to the information fed back by the first camera device 400 performing the first shooting action on the second sample container 20 located at the first shooting position; and determine that the blood sample 30 loaded in the second sample container 20 has no abnormal clot phenomenon according to the first target image 1011. In this embodiment, the control device 500 determines that the blood sample 30 loaded in the first sample container 20 has no abnormal clot phenomenon according to the first target image 1011, and then controls the measuring mechanism 230 to measure the first test liquid made of at least the upper layer liquid 31 and the reagent distributed in the first reaction container. That is, the node at which the control device 500 controls the measuring mechanism 230 to measure the first test liquid made of at least the upper layer liquid 31 distributed into the first reaction container and the reagent is located after it is determined that the blood sample 30 loaded in the second sample-free container 20 has no abnormal clot phenomenon according to the first target image 1011.

[0172] As an embodiment, there is a boundary liquid surface 321 or a boundary liquid layer between the middle layer liquid 32 and the upper layer liquid 31; the first target image 1011 at least includes an image showing the boundary liquid surface 321 or the boundary liquid layer in a two-dimensional form and / or a three-dimensional form. The first target image 1011 can show an image of a white film layer. For the sake of ease of description and understanding, the first target image 1011 can also be referred to as a white film layer image. A one-dimensional form refers to a form that extends in only one direction, and a one-dimensional form has only length elements, such as a line, a point, etc. A two-dimensional form refers to a form that extends in only two directions, and a two-dimensional form has only two elements, length and width, such as a plane, etc. A three-dimensional form refers to a form that has three directions, and a three-dimensional form has three elements, length, width, and height. In the related art before this application, there is also a solution of using a camera device to shoot the sample container 20 from the side of the sample container 20. In the solution of this related art, although the image captured also includes an image of the interface liquid surface 321, the interface liquid surface 321 is displayed in the form of a line, which is used to determine the height position of the interface liquid surface 321. Due to the solution of this related art, the two-dimensional form and / or three-dimensional form of the interface liquid surface 321 or the interface liquid layer cannot be seen, so it cannot be used as a basis for clot detection of the intermediate layer liquid 32. In this application, the interface liquid surface 321 or the interface liquid layer is displayed in a two-dimensional form and / or a three-dimensional form by an image, which is conducive to seeing whether the interface liquid surface 321 or the interface liquid layer has an uneven problem, so that the image containing the interface liquid surface 321 or the interface liquid layer displayed in a two-dimensional form and / or a three-dimensional form can be used as a basis for clot detection of the intermediate layer liquid 32. The first camera device 400 captures the liquid surface image of the buffy coat layer from the oblique upper or oblique lower side of the intermediate layer liquid 32 loaded in the sample container 20, which helps to ensure that the two-dimensional liquid surface image and / or three-dimensional liquid surface image of the buffy coat layer, i.e., the two-dimensional and / or three-dimensional image of the interface liquid surface 321 or the interface liquid layer, is captured. By performing abnormal recognition on the buffy coat layer image, if the buffy coat layer image of the blood sample 30 is abnormal, it is considered that the blood sample 30 has a clot abnormality.

[0173] As an implementation manner, the above-mentioned determination of the presence of abnormal clots in the blood sample 30 loaded in the first sample container 20 according to the first target image 1011 is mainly based on algorithmic judgment of the buffy coat image. The specific algorithmic judgment method can be based on checking and judging whether the buffy coat is flat, or can be analyzed and judged by AI algorithms such as CNN convolutional neural network and other methods.

[0174] As an embodiment, the above-mentioned determining whether the blood sample 30 loaded in the first sample container 20 has abnormal clot phenomenon according to the first target image 1011 includes: extracting a target index for characterizing the flatness of the intermediate layer liquid 32 in the first target image 1011; comparing the target index with a preset index;

[0175] If the target index is greater than or equal to the preset index, it is determined that the blood sample 30 loaded in the first sample container 20 has abnormal clotting. It has been found that after centrifugation, the middle liquid layer of a normal blood sample 30 (blood sample 30 without abnormal clotting) is very flat; while the blood sample 30 with abnormal clotting is uneven in the middle liquid layer (sometimes it is uneven in the middle liquid layer, and sometimes it is covered with a layer of loose floating objects coagulated by fibrin, which is mainly caused by the different sizes, causes and time of the clots). The main reason for the unevenness of the middle liquid layer of the blood sample 30 with abnormal coagulation is that, for example, when the blood sample 30 and the anticoagulant are not mixed well, the blood sample 30 has already coagulated before centrifugation. The main mechanism of coagulation is that the fibrinogen in the plasma forms fibrin under the action of a series of coagulation factors, and the fibrin will wrap the blood cells to form a clot. After centrifugation, if the density of the clot is between that of red blood cells and plasma, the clot is near the middle liquid layer, which will cause the unevenness of the middle liquid layer. In addition, some parts of the formed clots wrap more platelets, while some parts wrap more red blood cells, so the density of the clots at different positions is different, which is also one of the reasons why the clots cause the unevenness of the middle liquid layer. In this embodiment, the target index of the white film layer image (i.e., the first target image 1011) obtained by shooting is extracted to characterize the flatness of the white film layer (for example, the number and / or size of the concave-convex structure used to characterize the flatness of the white film layer), and the target index is compared with the preset index. When the target index is higher than the preset index, it is determined that the blood sample 30 has abnormal clotting phenomenon, otherwise it is determined that the blood sample 30 has no abnormal clotting phenomenon.

[0176] Of course, in specific applications, it is not limited to analyzing the buffy coat image by target indicators to determine whether the blood sample 30 has abnormal clotting phenomenon. For example, as an alternative embodiment, the above-mentioned determination of the presence of abnormal clotting phenomenon in the blood sample 30 loaded in the first sample container 20 according to the first target image 1011 includes: extracting target features in the first target image 1011; comparing the target features with preset features; if the similarity between the target features and the preset features is greater than or equal to a first preset threshold, then determining that the blood sample 30 loaded in the first sample container 20 has abnormal clotting phenomenon. In this alternative embodiment, based on target feature detection (for example, features for characterizing clots), by extracting the target features in the captured buffy coat image (i.e., the first target image 1011), and comparing the target features with the preset features, when the similarity or matching degree between the target features and the preset features reaches the first preset threshold, then determining that the blood sample 30 has abnormal clotting phenomenon, otherwise determining that the blood sample 30 has no abnormal clotting phenomenon.

[0177] Alternatively, as another alternative embodiment, the above-mentioned determination of the presence of abnormal clotting phenomenon in the blood sample 30 loaded in the first sample container 20 according to the first target image 1011 includes: comparing the first target image 1011 with a preset image; if the similarity between the first target image 1011 and the preset image is greater than or equal to a second preset threshold, determining that the blood sample 30 loaded in the first sample container 20 has abnormal clotting phenomenon. In this alternative embodiment, by pre-storing one or more preset images with abnormal clotting phenomenon in the sample analysis system 10, the entire buffy coat layer image (i.e., the first target image 1011) is directly compared with the preset image pre-stored in the sample analysis system 10, and when the similarity or matching degree between the photographed buffy coat layer image and the preset image reaches the second preset threshold, it is determined that the blood sample 30 has abnormal clotting phenomenon.

[0178] As an embodiment, the sample measuring device 200 further includes a reagent dispensing mechanism 250 , and the reagent dispensing mechanism 250 is used to dispense the reagent into the reaction container.

[0179] As an embodiment, the sample measuring device 200 further includes an incubation mechanism 240 , and the incubation mechanism 240 is used to incubate the liquid in the reaction container including at least the upper layer liquid 31 .

[0180] As an embodiment, the control device 500 controls the sample container transfer device 300 to transfer the first sample container 20 loaded with a blood sample 30 and having an abnormal clotting phenomenon in the blood sample 30 to a node of the first storage space, which is located after the control device 500 determines that the blood sample 30 loaded in the first sample container 20 has an abnormal clotting phenomenon according to the first target image 1011. After the first camera device 400 completes the first shooting action on the first sample container 20, the control device 500 needs time to analyze the first target image 1011 to determine whether the blood sample 30 loaded in the first sample container 20 has a clotting abnormality. Therefore, when the control device 500 completes the analysis of the first target image 1011 and determines that the blood sample 30 loaded in the first sample container 20 has a clotting abnormality, the first sample container 20 may be in one of the following nodes: 1) It has not been transferred to the sample measuring device 200 by the sample container transmission device 300; 2) It has been transferred to the sample measuring device 200 by the sample container transmission device 300, but the sample measuring device 200 has not yet sucked the sample from the first sample container 20; 3) It has been transferred to the sample measuring device 200 by the sample container transmission device 300, and the sample measuring device 200 has not yet sucked the sample from the first sample container 20. 200 has been aspirated from the first sample container 20 and distributed to the reaction container, but the sample measuring device 200 has not yet distributed the reagent to the reaction container containing the blood sample 30; 4) has been transferred to the sample measuring device 200 by the sample container transfer device 300, and the sample measuring device 200 has aspirated from the first sample container 20 and distributed to the reaction container, but the sample measuring device 200 has not yet incubated the reaction container containing the blood sample 30; 5) has been transferred to the sample measuring device 200 by the sample container transfer device 300, and the sample measuring device 200 has aspirated from the first sample container 20 and distributed to the reaction container, and has distributed the reagent to the reaction container containing the blood sample 30 and incubated the reaction container, but the measuring mechanism 230 has not yet measured the test liquid in the reaction container made of at least the blood sample 30 and the reagent. Since at these nodes, the measuring mechanism 230 has not yet measured the blood sample 30 with the abnormal clotting phenomenon, the control device 500 completes the analysis of the first target image 1011 at these nodes and determines that the blood sample 30 loaded in the first sample container 20 has the abnormal clotting phenomenon, and controls the sample container transfer device 300 to transfer the blood sample 30 with the abnormal clotting phenomenon to the first storage space, which can effectively prevent the measuring mechanism 230 from measuring the blood sample 30 with the abnormal clotting phenomenon, thereby at least saving the time for the measuring mechanism 230 to measure the blood sample 30 with the abnormal clotting phenomenon, and further helping to improve the sample measurement efficiency of the sample analysis system 10.

[0181] As an embodiment, the above-mentioned controlling the sample container transporting device 300 to transport the first sample container 20 after completing the first shooting action and before the upper layer liquid 31 thereof is measured by the measuring mechanism 230 to the first storage space includes: controlling the sample container transporting device 300 to transport the first sample container 20 after completing the first shooting action and before the sample container transporting device 300 is transported to the sample measuring device 200 to the first storage space. In this embodiment, the node at which the control device 500 completes the analysis of the first target image 1011 and determines whether the blood sample 30 loaded in the first sample container 20 has a clot abnormality is, for example, before the first sample container 20 is transported to the sample measuring device 200 by the sample container transporting device 300, that is, the first sample container 20 is still in the first shooting position, or the first sample container 20 is located in the path of the sample container transporting device 300 transporting it toward the sample measuring device 200, or the first sample container 20 is placed in a cache position after completing the first shooting action to wait for the conclusion of the control device 500 determining whether the blood sample 30 loaded in the first sample container 20 has a clot abnormality. Since the blood sample 30 with abnormal clotting phenomenon has a node that is rolled back before the blood sample 30 is transmitted to the sample measuring device 200, that is, after the blood sample 30 with abnormal clotting phenomenon is photographed by the first camera device 400, it will not be transmitted to the sample measuring device 200, but will be transmitted to the first storage space for recovery. In this way, the sample measuring device 200 will not perform the sample suction action, reagent addition action, incubation action and measurement action on the blood sample 30 with abnormal clotting phenomenon, which is beneficial to reduce the waste of consumables such as reaction containers and reagents, and avoid the blood sample 30 from occupying the resources of the sample measuring device 200, thereby improving the measurement efficiency of batch blood samples 30.

[0182] Alternatively, as another embodiment, the above-mentioned controlling the sample container transporting device 300 to transport the first sample container 20 after the first shooting action is completed and the upper layer liquid 31 loaded therein has not been measured by the measuring mechanism 230 to the first storage space includes: controlling the sample container transporting device 300 to transport the first sample container 20 after the first shooting action is completed to the sample measuring device 200, and controlling the sample container transporting device 300 to transport the first sample container 20 output from the sample measuring device 200 and the upper layer liquid 31 has not been sucked out of it by the sample dispensing mechanism 220 to the first storage space. In this embodiment, the node at which the control device 500 completes the analysis of the first target image 1011 and determines that the blood sample 30 loaded in the first sample container 20 has a clot abnormality phenomenon, before the sample measuring device 200 sucks the sample from the first sample container 20, for example, can be the first sample container 20 in the loading area or buffer area or the sample suction channel 210 or the sample suction position of the sample measuring device 200. Since the blood sample 30 with abnormal clotting phenomenon has a node that is retracted, it is located before the sample measuring device 200 aspirates the sample from the first sample container 20, that is, the blood sample 30 with abnormal clotting phenomenon will be transmitted to the sample measuring device 200 after the first camera device 400 completes the shooting, but will not be aspirated and measured by the sample measuring device, but will be transmitted to the first storage space for recovery before aspirating the sample. In this way, the sample measuring device 200 will not perform aspirating, reagent adding, incubating and measuring actions on the blood sample 30 with abnormal clotting phenomenon, which is beneficial to reducing the waste of consumables such as reaction containers and reagents, and avoiding the occupation of resources of the sample measuring device 200 by the blood sample 30, thereby improving the measurement efficiency of batch blood samples 30.

[0183] Alternatively, as another embodiment, the above-mentioned control of the sample container transmission device 300 to transmit the first sample container 20 after completing the first shooting action and before the upper layer liquid 31 loaded therein is measured by the measuring mechanism 230 to the first storage space includes: controlling the sample container transmission device 300 to transmit the first sample container 20 after completing the first shooting action to the sample measuring device 200, controlling the sample dispensing mechanism 220 to absorb at least part of the upper layer liquid 31 from the first sample container 20 and distribute it to the second reaction container, and controlling the sample container transmission device 300 to transmit the first sample container 20 output from the sample measuring device 200 and before the reagent dispensing mechanism 250 distributes the reagent to the second reaction container to the first storage space. In the present embodiment, the control device 500 completes the analysis of the first target image 1011 and determines the node at which the blood sample 30 loaded in the first sample container 20 has an abnormal clotting phenomenon, before the reagent dispensing mechanism 250 dispenses the reagent to the second reaction container, for example, the second reaction container may be after the sample is loaded at the loading position or the second reaction container after loading is on the way to the incubation mechanism 240 or the second reaction container after loading is on the incubation mechanism 240 or the second reaction container after loading is on the way to the reagent loading position or the second reaction container after loading is at the reagent loading position. Since the blood sample 30 with abnormal clotting phenomenon exists, the node to be rolled back is located before the sample measuring device 200 distributes the reagent to the second reaction container, that is, after the blood sample 30 with abnormal clotting phenomenon is photographed by the first camera device 400, it will be transmitted to the sample measuring device 200 for sample aspiration, but the actions of adding reagent and measuring will not be performed after sample aspiration, but the blood sample 30 will be transmitted to the first storage space for recovery before adding reagent. In this way, the sample measuring device 200 will not perform the actions of adding reagent and measuring on the blood sample 30 with abnormal clotting phenomenon, which is beneficial to reduce the waste of reagents and avoid the occupation of resources of the sample measuring device 200 by the blood sample 30, thereby improving the measurement efficiency of batch blood samples 30.

[0184] Alternatively, as yet another embodiment, controlling the sample container transmission device 300 to transmit the first sample container 20 after completing the first shooting action and without the upper layer liquid 31 loaded therein being measured by the measuring mechanism 230 to the first storage space includes: controlling the sample container transmission device 300 to transmit the first sample container 20 after completing the first shooting action to the sample measuring device 200, controlling the sample dispensing mechanism 220 to absorb at least a portion of the upper layer liquid 31 from the first sample container 20 and distribute it to the second reaction container, and controlling the sample container transmission device 300 to transmit the first sample container 20 output from the sample measuring device 200 and without the incubation mechanism 240 to incubate the liquid in the second reaction container at least containing the upper layer liquid 31 distributed from the first sample container 20 to the second reaction container to the first storage space. In this embodiment, the control device 500 completes the analysis of the first target image 1011 and determines the node where the blood sample 30 loaded in the first sample container 20 has an abnormal clotting phenomenon, before the incubation mechanism 240 incubates the liquid in the second reaction container containing at least the upper layer of liquid 31, for example, the second reaction container may be after the sample is loaded at the loading position or the second reaction container after the sample is loaded is on the way to the incubation mechanism 240 or the second reaction container after the sample is loaded is on the incubation mechanism 240. Since the blood sample 30 with abnormal clotting phenomenon has a node that is retracted, it is located before the sample measuring device 200 incubates the liquid in the second reaction container, that is, after the blood sample 30 with abnormal clotting phenomenon is photographed by the first camera device 400, it will be transmitted to the sample measuring device 200 for sample aspiration, but no incubation and measurement will be performed after sample aspiration. Instead, it will be transmitted to the first storage space for recovery before incubation. In this way, the sample measuring device 200 will not perform incubation and measurement actions on the blood sample 30 with abnormal clotting phenomenon, which is beneficial to avoid the blood sample 30 occupying the resources of the sample measuring device 200, thereby helping to improve the measurement efficiency of batch blood samples 30.

[0185] Alternatively, as another embodiment, controlling the sample container transmission device 300 to transmit the first sample container 20 after completing the first shooting action and before the upper layer liquid 31 loaded therein is measured by the measuring mechanism 230 to the first storage space includes: controlling the sample container transmission device 300 to transmit the first sample container 20 after completing the first shooting action to the sample measuring device 200, controlling the sample dispensing mechanism 220 to absorb at least a portion of the upper layer liquid 31 from the first sample container 20 and distribute it to the second reaction container, controlling the incubation mechanism 240 to incubate the liquid in the second reaction container at least containing the upper layer liquid 31 distributed from the first sample container 20 to the second reaction container, controlling the reagent dispensing mechanism 250 to distribute the reagent to the second reaction container, and controlling the sample container transmission device 300 to transmit the first sample container 20 output from the sample measuring device 200 and before the second liquid to be tested containing at least the upper layer liquid 31 distributed to the second reaction container and the reagent to the second reaction container to the first storage space. In this embodiment, the control device 500 completes the analysis of the first target image 1011 and determines the node where the blood sample 30 loaded in the first sample container 20 has the abnormal clotting phenomenon, before the measuring mechanism 230 measures the second test liquid in the second reaction container at least including the upper layer liquid 31 and the reagent, for example, after the second reaction container has finished adding the reagent at the reagent adding position or during the process of the second reaction container after adding the reagent being transferred to the measuring mechanism 230 or the second reaction container is on the incubation mechanism 240. Since the blood sample 30 with the abnormal clotting phenomenon is returned to the node before the sample measuring device 200 measures the liquid in the second reaction container, the sample measuring device 200 will not perform the measuring action on the blood sample 30 with the abnormal clotting phenomenon, which is conducive to avoiding the occupation of the resources of the sample measuring device 200 by the blood sample 30, thereby facilitating the improvement of the measuring efficiency of the batch blood samples 30.

[0186] As an embodiment, when a first sample container 20 loaded with a blood sample 30 and in which a clotting abnormality exists is placed in the sample management device 100, after controlling the first camera device 400 to perform a first shooting action on the first sample container 20 located at the first shooting position, the control device 500 is further configured to: output a prompt message for indicating that the blood sample 30 in the first sample container 20 has a clotting abnormality, so as to help remind the operator to intervene in the processing of the blood sample 30 with the clotting abnormality, for example: manually review whether the blood sample 30 actually has a clotting abnormality, and when it is determined that a clotting abnormality exists, the blood sample 30 can be collected from the patient again or the blood sample 30 can be processed to eliminate the clot, etc.

[0187] As an embodiment, the output of the prompt information indicating that the blood sample 30 in the first sample container 20 has an abnormal clot phenomenon is performed after the control device 500 completes the analysis of the first target image 1011 and determines that the blood sample 30 loaded in the first sample container 20 has an abnormal clot phenomenon. That is, when the first sample container 20 loaded with the blood sample 30 and the blood sample 30 having an abnormal clot phenomenon is placed in the sample management device 100, after the control device 500 completes the analysis of the first target image 1011 and determines that the blood sample 30 loaded in the first sample container 20 has an abnormal clot phenomenon, the control device 500 is further configured to output the prompt information indicating that the blood sample 30 in the first sample container 20 has an abnormal clot phenomenon.

[0188] As an embodiment, the output of the prompt information indicating that the blood sample 30 in the first sample container 20 has a coagulation abnormality is performed after the sample container transport device 300 is controlled to transport the first sample container 20 that has completed the first shooting action and has not been measured by the measuring mechanism 230 and the upper layer liquid 31 thereof to the first storage space, that is, after the sample container transport device 300 is controlled to transport the first sample container 20 that has completed the first shooting action and has not been measured by the measuring mechanism 230 and the upper layer liquid 31 thereof to the first storage space, the control device 500 is further configured to: output the prompt information indicating that the blood sample 30 in the first sample container 20 has a coagulation abnormality. In this embodiment, the output of the prompt information indicating that the blood sample 30 in the first sample container 20 has a coagulation abnormality is performed after the sample container transport device 300 transports the first sample container 20 that has the blood sample 30 that has a coagulation abnormality to the first storage space, so that the operator can quickly process the first sample container 20 that has the blood sample 30 that has a coagulation abnormality according to the prompt information.

[0189] Of course, in a specific application, outputting the prompt information for indicating that the blood sample 30 in the first sample container 20 has a coagulation abnormality is not limited to being executed after the blood sample 30 with the coagulation abnormality is transferred to the first storage space. For example, as an alternative embodiment, in the process of controlling the sample container transfer device 300 to transfer the first sample container 20 after completing the first shooting action and before the upper layer liquid 31 loaded therein is measured by the measuring mechanism 230 to the first storage space, the control device 500 is further configured to: output the prompt information for indicating that the blood sample 30 in the first sample container 20 has a coagulation abnormality; or, as another alternative embodiment, after controlling the first camera device 400 to perform the first shooting action on the first sample container 20 located at the first shooting position, and before controlling the sample container transfer device 300 to transfer the first sample container 20 after completing the first shooting action and before the upper layer liquid 31 loaded therein is measured by the measuring mechanism 230 to the first storage space, the control device 500 is further configured to: output the prompt information for indicating that the blood sample 30 in the first sample container 20 has a coagulation abnormality. Specifically, the control device 500 is also configured to: output prompt information for characterizing the presence of abnormal clotting phenomenon in the blood sample 30 in the first sample container 20 at one of the following nodes: after controlling the sample container transmission device 300 to transmit the first sample container 20 after completing the first shooting action and before the upper layer liquid 31 loaded therein is measured by the measuring mechanism 230 to the first storage space; during the process of controlling the sample container transmission device 300 to transmit the first sample container 20 after completing the first shooting action and before the upper layer liquid 31 loaded therein is measured by the measuring mechanism 230 to the first storage space; after controlling the first camera device 400 to perform the first shooting action on the first sample container 20 located at the first shooting position, and before controlling the sample container transmission device 300 to transmit the first sample container 20 after completing the first shooting action and before the upper layer liquid 31 loaded therein is measured by the measuring mechanism 230 to the first storage space. After controlling the first camera device 400 to perform a first shooting action on the first sample container 20 located at the first shooting position, prompt information for indicating that there is an abnormal clot phenomenon in the blood sample 30 in the first sample container 20 can be output after the sample container transmission device 300 transmits the first sample container 20 to the first storage space, or before the sample container transmission device 300 transmits the first sample container 20 to the first storage space, or during the process of the sample container transmission device 300 transmitting the first sample container 20 to the first storage space.

[0190] As an embodiment, the sample analysis system 10 further includes a first display screen 101, which is independently provided with the sample measuring device 200, and is used to display at least the storage information of the blood sample 30 in the sample management device 100 and the information of the blood sample 30 transmitted by the sample container transmission device 300, and outputting the prompt information indicating that the blood sample 30 in the first sample container 20 has an abnormal clot phenomenon includes: controlling the first display screen 101 to display the prompt information indicating that the blood sample 30 in the first sample container 20 has an abnormal clot phenomenon. In this embodiment, the sample analysis system 10 is a sample analysis pipeline or a sample analysis cascade system, and the sample analysis system 10 includes at least two sample measuring devices 200, and the at least two sample measuring devices 200 are respectively connected to the sample container transmission device 300. The first display screen 101 is a display screen at the operation end of the sample analysis pipeline or the sample analysis cascade system. The prompt information indicating that the blood sample 30 in the first sample container 20 has abnormal clotting phenomenon is set to be displayed on the first display screen 101, so that the operator can more conveniently and quickly obtain the prompt information and process the blood sample 30 with abnormal clotting phenomenon.

[0191] In a specific application, the output of the prompt information indicating that the blood sample 30 in the first sample container 20 has an abnormal clot phenomenon can also be displayed on other display screens. For example, as an embodiment, the sample measuring device 200 further includes a second display screen, which is used to display at least the measurement item information of the blood sample 30 in the sample measuring device 200. The output of the prompt information indicating that the blood sample 30 in the first sample container 20 has an abnormal clot phenomenon includes: controlling the second display screen to display the prompt information indicating that the blood sample 30 in the first sample container 20 has an abnormal clot phenomenon. The second display screen is a display screen provided by the sample measuring device 200, that is, a display screen of a stand-alone sample analyzer.

[0192] Alternatively, as another embodiment, the above-mentioned output of the prompt information for characterizing the presence of abnormal clotting phenomenon in the blood sample 30 in the first sample container 20 includes: transmitting the prompt information for characterizing the presence of abnormal clotting phenomenon in the blood sample 30 in the first sample container 20 to a laboratory information management system (i.e., LIS system) that is communicatively connected to the sample analysis system 10.

[0193] Alternatively, as another embodiment, the sample analysis system 10 further includes an alarm device, the alarm device includes a sound alarm component and / or a light alarm component, and outputting the prompt information for indicating that the blood sample 30 in the first sample container 20 has an abnormal clot phenomenon includes: controlling the alarm device to issue a sound alarm signal and / or a light alarm signal for indicating that the blood sample 30 in the first sample container 20 has an abnormal clot phenomenon. That is, the prompt information for indicating that the blood sample 30 in the first sample container 20 has an abnormal clot phenomenon can be issued through a sound alarm or a light alarm signal.

[0194] As an implementation manner, the first display screen 101 is located beside the sample management device 100 or beside the sample container transmission device 300 .

[0195] As an embodiment, the control device 500 is further configured to: control the first display screen 101 to display the first target image 1011 and the second target image 1012, so as to facilitate the operator to review the quality information of the blood sample 30, thereby improving the intuitiveness and efficiency of the review.

[0196] As an implementation manner, the control device 500 is further configured to: control the first display screen 101 to display the first target image 1011 and the second target image 1012 on the same interface.

[0197] As an embodiment, the control device 500 is further configured to: control the first display screen 101 to display the first target image 1011, the second target image 1012, the hematocrit test result, the clot test result, the fluid volume test result, the hemolysis test result, the jaundice test result and the lipemia test result on the same interface. In this way, it is helpful to reduce the time for operators to find relevant information on the quality test of the blood sample 30, and further help to improve the intuitive and rapid judgment or review of the quality of the blood sample 30, and finally help to improve the efficiency of the quality review of the blood sample 30.

[0198] As an embodiment, the control of the sample container transport device 300 to transport the first sample container 20 after the first shooting action is completed and the upper layer liquid 31 loaded therein has not been measured by the measuring mechanism 230 to the first storage space includes: controlling the sample container transport device 300 to transport the first sample container 20 to the first storage space along a first route. The control of the sample container transport device 300 to transport the second sample container 20 after the first shooting action is completed to the sample measuring device 200 includes: controlling the sample container transport device 300 to transport the second sample container 20 to the sample measuring device 200 along a second route; wherein the first route and the second route are at least partially different. In this embodiment, after the control device 500 completes the analysis of the first target image 1011 and draws a conclusion on whether the blood sample 30 loaded in the sample container 20 has the abnormal clotting phenomenon, the blood sample 30 with the abnormal clotting phenomenon and the blood sample 30 without the abnormal clotting phenomenon are respectively transmitted along different routes, wherein the blood sample 30 with the abnormal clotting phenomenon is transmitted along one route toward the first storage space, and the blood sample 30 without the abnormal clotting phenomenon is transmitted along another route toward the sample measuring device 200, thereby facilitating the recovery and processing of the blood sample 30 with the abnormal clotting phenomenon and the sampling and measurement of the blood sample 30 without the abnormal clotting phenomenon.

[0199] As an embodiment, the sample analysis system 10 further includes a first reflector 600, and the first reflector 600 is used to: when the first camera device 400 performs the first shooting action, reflect the image of the sample container 20 to the first camera device 400; the first camera device 400 performs the first shooting action on the sample container 20 includes: the first camera device 400 shoots the image of the sample container 20 in the first reflector 600 toward the first reflector 600. Specifically, the first camera device 400 performs the first shooting action on the sample container 20 includes: the first camera device 400 indirectly shoots the image of the sample container 20 through the first reflector 600 from the oblique upper or oblique lower side of the intermediate layer liquid 32. The first reflector 600 is used to: when the first camera device 400 performs the first shooting action, reflect the image at least including the interface liquid surface 321 or the interface liquid layer displayed in a two-dimensional form and / or a three-dimensional form to the first camera device 400. Since there are requirements for the focal position when the first camera device 400 performs the first shooting action, in this embodiment, the first reflector 600 is used to reflect the image of the interface liquid surface 321 or the interface liquid layer in a two-dimensional form and / or a three-dimensional form to the first camera device 400, which is beneficial to change the propagation path of the light, so that the shooting focal position of the first camera device 400 is converted to the distance between the first camera device 400 and the first reflector 600, thereby facilitating the reduction of the distance between the first camera device 400 and the sample container 20, and further facilitating the reduction of the volume of the sample analysis system 10.

[0200] Of course, in a specific application, the sample analysis system 10 may not be provided with the first reflector 600. For example, as an alternative embodiment, the first camera device 400 directly faces the sample container 20 from the oblique upper or lower side of the intermediate layer of liquid 32 to capture the image of the sample container 20. That is, the first camera device 400 directly captures the image of the sample container 20 from the oblique upper or lower side of the intermediate layer of liquid 32. As a further embodiment of the alternative embodiment, the first camera device 400 performs a first capturing action on the sample container 20, including: the first camera device 400 is used to capture the image of the sample container 20 directly faces the sample container 20 from the oblique upper side of the intermediate layer of liquid 32 in a posture where the camera optical axis forms a preset angle with the horizontal direction, and the preset angle is greater than or equal to 10° and less than or equal to 70°.

[0201] As an embodiment, the first reflector 600 is tilted relative to the horizontal direction. The optical axis of the first camera device 400 when performing the first shooting action is perpendicular to the horizontal direction, that is, the optical axis of the first camera device 400 when performing the first shooting action is arranged in the vertical direction. The first camera device 400 can be arranged above or below the first reflector 600 in the vertical direction. Since the sample container 20 is arranged in the vertical direction when performing the first shooting action, that is, the height direction of the sample container 20 is parallel to the vertical direction, the optical axis of the first camera device 400 is parallel to the height direction of the sample container 20, which is conducive to reducing the horizontal distance between the first camera device 400 and the sample container 20, thereby helping to reduce the horizontal footprint of the sample analysis system 10. Of course, in specific applications, the arrangement of the first reflector 600 and the first camera device 400 is not limited to this. For example, the position and orientation of the first reflector 600 and the first camera device 400 can also be adjusted, that is, the camera optical axis of the first camera device 400 is not necessarily along the vertical direction, and can also have a certain inclination angle, as long as the first camera device 400 can capture an image containing the interface liquid surface 321 or the interface liquid layer displayed in two-dimensional form and / or three-dimensional form through the first reflector 600.

[0202] As an embodiment, the first reflector 600 is used to reflect the image of the sample container 20 from the oblique upper side of the intermediate layer liquid 32 when the first camera device 400 performs the first shooting action; the first camera device 400 is used to shoot the image of the sample container 20 in the first reflector 600 when performing the first shooting action. In this embodiment, the first reflector 600 reflects upward from the side of the sample container 20 an image including the interface liquid surface 321 or the interface liquid layer displayed in a two-dimensional form and / or a three-dimensional form, and the first camera device 400 shoots the image including the interface liquid surface 321 or the interface liquid layer displayed in a two-dimensional form and / or a three-dimensional form in the first reflector 600 from above the first reflector 600. Of course, in specific applications, the relative positions of the first reflector 600 and the first camera device 400 are not limited thereto. For example, as an alternative embodiment, the first reflector 600 is used to reflect the image of the sample container 20 from obliquely below the intermediate layer of liquid 32 when the first camera device 400 performs the first shooting action; the first camera device 400 is used to capture the image of the sample container 20 in the first reflector 600 when performing the first shooting action. In this alternative embodiment, the first reflector 600 reflects downward from the side of the sample container 20 an image including the interface liquid surface 321 or the interface liquid layer displayed in a two-dimensional form and / or a three-dimensional form, and the first camera device 400 captures the image including the interface liquid surface 321 or the interface liquid layer displayed in a two-dimensional form and / or a three-dimensional form in the first reflector 600 from below the first reflector 600.

[0203] As an implementation manner, the sample analysis system 10 further includes a first fill light component 800, which is used to emit light toward the sample container 20 to illuminate the sample container 20 during the first shooting action, that is, the first fill light component 800 is used to fill light for shooting of the first camera device 400. The first fill light component 800 can be disposed on the front or side of the sample container 20, or on the top or other positions of the sample container 20.

[0204] As an implementation manner, the first camera device 400 is a first camera, and the first fill light component 800 is an array LED that has been homogenized. Its main purpose is to fill light for the white film layer in the field of view of the first camera to at least illuminate the white film layer.

[0205] As an embodiment, the sample analysis system 10 further includes a second camera device 700, which is used to perform a second shooting action on the sample container 20 before the sample dispensing mechanism 220 absorbs at least part of the upper layer of liquid 31 from the sample container 20. The control device 500 is further configured to: obtain a second target image 1012 according to the information fed back by the second camera device 700 when performing the second shooting action; and obtain at least one of the following information according to the second target image 1012: the total liquid volume of the blood sample 30 in the sample container 20, the hematocrit of the blood sample 30 in the sample container 20, the hemolysis index of the blood sample 30 in the sample container 20, the icterus index of the blood sample 30 in the sample container 20, and the lipemia index of the blood sample 30 in the sample container 20. In this embodiment, at least one of the hematocrit detection result, the liquid volume detection result, the hemolysis detection result, the icterus detection result, and the lipemia detection result is obtained through the second target image 1012, and the detection method is simple.

[0206] As an embodiment, the control device 500 is also configured to obtain at least two of the following information based on the second target image 1012: the total liquid volume of the blood sample 30 in the sample container 20, the hematocrit of the blood sample 30 in the sample container 20, the hemolytic index of the blood sample 30 in the sample container 20, the icterus index of the blood sample 30 in the sample container 20, and the lipemia index of the blood sample 30 in the sample container 20.

[0207] As an embodiment, the control device 500 is also configured to obtain all of the following information based on the second target image 1012: the total liquid volume of the blood sample 30 in the sample container 20, the hematocrit of the blood sample 30 in the sample container 20, the hemolytic index of the blood sample 30 in the sample container 20, the icterus index of the blood sample 30 in the sample container 20, and the lipemia index of the blood sample 30 in the sample container 20.

[0208] As an embodiment, the second target image 1012 at least includes an image showing the entire height of one side of the sample container 20 in a two-dimensional and / or three-dimensional form, or at least includes an image showing the entire blood sample 30 in the sample container 20 in a two-dimensional and / or three-dimensional form, or at least includes an image showing the liquid surface of the upper liquid 31, the liquid surface of the middle layer liquid 32 and the liquid surface of the lower layer liquid 33 in the sample container 20, or at least includes an image showing the entire upper liquid 31, the entire middle layer liquid 32 and the entire lower layer liquid 33 in the sample container 20 in a two-dimensional and / or three-dimensional form, or at least includes an image showing at least one side of the bottom, middle part and top of the sample container 20 in a two-dimensional and / or three-dimensional form. The second target image 1012 is a full-view image of the sample container 20 (it may be a full-view image of the sample container 20 with a cap, or it may be a full-view image of the sample container 20 without a cap, or it may be a full-view image of the sample container 20 with a stopper, or it may be a full-view image of the sample container 20 without a stopper), which may at least display the entire height information of the sample container 20; or the second target image 1012 is a full-view image of the blood sample 30 in the sample container 20, which may at least display the height information of the three liquid levels of the blood sample 30 in the sample container 20 or the entire height information. For the convenience of description and understanding, the second target image 1012 may also be referred to as a full-view image of the blood sample 30.

[0209] As an implementation manner, the second camera device 700 and the first camera device 400 are two independent camera devices, that is, the second camera device 700 and the first camera device 400 are two different camera devices, rather than the same camera device. In this implementation manner, by setting two camera devices, one of which is used to capture the full image of the blood sample 30, and the other is used to capture the white film layer image of the blood sample 30, the full image of one blood sample 30 and the white film layer image of another blood sample 30 can be captured in parallel, thereby facilitating the improvement of the detection efficiency of batch blood samples 30. Of course, in a specific application, as an alternative implementation manner, the second camera device 700 and the first camera device 400 can also be set as the same camera device.

[0210] As an implementation manner, the first camera device 400 and the second camera device 700 are respectively located at two different positions. Of course, in a specific application, as an alternative implementation manner, the first camera device 400 and the second camera device 700 can also be located at the same position.

[0211] As an embodiment, the second camera device 700 is located in front of the first camera device 400 along the transmission direction of the sample container 20. The sample container 20 is first transmitted to the shooting position of the second camera device 700 for shooting, and then transmitted to the shooting position of the first camera device 400 for shooting.

[0212] As an embodiment, the second camera device 700 is used to perform a second shooting action on the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and layered, before the first camera device 400 performs the first shooting action on the sample container 20, that is, the second camera device 700 is used to shoot an image of the sample container 20 from the side of the sample container 20 in the horizontal direction. The height direction of the sample container 20 is parallel to the vertical direction, and the shooting optical axis of the second camera device 700 is perpendicular to the height direction of the sample container 20. In this way, it is convenient for the control device 500 to accurately obtain the total liquid level of the blood sample 30 and the height of the lower layer of liquid 33 according to the image captured by the second camera device 700.

[0213] As an embodiment, the second camera device 700 performs the second shooting action on the sample container 20, including: the second camera device 700 directly shoots the image of the sample container 20 from the side of the sample container 20 or indirectly shoots the image of the sample container 20 through the second reflector 102. That is, the second camera device 700 is used to directly or indirectly shoot the image of the sample container 20 and / or the blood sample 30 in the sample container 20.

[0214] As an embodiment, the camera device further includes a second reflector 102, and the second reflector 102 is used to: when the second camera device 700 performs the second shooting action, reflect at least an image showing the whole picture of the sample container 20 in a two-dimensional form and / or a three-dimensional form to the second camera device 700. The second camera device 700 performs the second shooting action on the sample container 20, including: the second camera device 700 indirectly shoots the image of the sample container 20 through the second reflector 102. Of course, in a specific application, the sample analysis system 10 may also not be provided with the second reflector 102. For example, as an alternative embodiment, the second camera device 700 performs the second shooting action on the sample container 20, including: the second camera device 700 directly shoots the image of the sample container 20 from the side of the sample container 20.

[0215] As an implementation manner, the second camera device 700 is a second camera, and the sample analysis system 10 further includes a second fill light component 103. The second camera captures the full view of the blood sample 30 from the side of the sample container 20. The second fill light component 103 is mainly used to fill light for the full view of the blood sample 30 in the field of view of the second camera, so as to at least illuminate all the blood samples 30 in the sample container 20.

[0216] As an embodiment, the second camera device 700 is used to perform a second shooting action on the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and layered, in a horizontal direction, before the first camera device 400 performs the first shooting action on the sample container 20. The control device 500 is also configured to: before acquiring the first target image 1011, first control the second camera device 700 to perform the second shooting action on the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and layered, obtain the height position of the interface liquid surface 321 or the interface liquid layer according to the image captured by the second camera device 700 when performing the second shooting action, and obtain the target height position according to the height position of the interface liquid surface 321 or the interface liquid layer. The above-mentioned obtaining of the first target image 1011 includes: controlling one of the sample container 20 and the first camera device 400 to move relative to the other and stop at a target height position, controlling the first camera device 400 to perform a first shooting action on the sample container 20, and obtaining the first target image 1011 according to the image captured by the first camera device 400 when performing the first shooting action. The target height position can be a specific height position or a height range value. Since the first camera device 400 has a requirement for the focus position when performing the shooting action of the white film layer, before performing the shooting action of the white film layer, the height position of the interface liquid surface 321 or the interface liquid layer is first found, and then the shooting action of the white film layer is performed based on the height position, which is conducive to ensuring the clarity of the image of the interface liquid surface 321 or the interface liquid layer.

[0217] As an embodiment, the control device 500 is further configured to: before acquiring the first target image 1011, first control the second camera device 700 to perform a second shooting action on the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and layered, obtain the height position of the interface liquid surface 321 or the interface liquid layer according to the image captured by the second camera device 700 in the second shooting action, and obtain the target height position according to the height position of the interface liquid surface 321 or the interface liquid layer. Obtain the first target image 1011 according to the information fed back by the first camera device 400 in the first shooting action, including: controlling one of the sample container 20 and the first camera device 400 to move relative to the other and stop at the target height position, controlling the first camera device 400 to perform the first shooting action on the sample container 20, and obtaining the first target image 1011 according to the image captured by the first camera device 400 in the first shooting action. The target height position can be a specific height position or a height range value. Since the first camera device 400 has requirements on the focus position when performing the shooting action of the white film layer, before performing the shooting action of the white film layer, the height position of the interface liquid surface 321 or the interface liquid layer is first found, and then the shooting action of the white film layer is performed based on the height position, which is beneficial to ensure the clarity of the image of the interface liquid surface 321 or the interface liquid layer.

[0218] As an embodiment, the control device 500 is further configured to: when a third sample container 20 loaded with a blood sample 30 and having a total liquid volume less than a first threshold value, or a hematocrit of the blood sample 30 greater than a second threshold value, or a hematocrit of the blood sample 30 less than a third threshold value, or a hemolytic index of the blood sample 30 greater than a fourth threshold value, or a icteric index of the blood sample 30 greater than a fifth threshold value, or a lipemia index of the blood sample 30 greater than a sixth threshold value is placed in the sample management device 100, control the sample container transfer device 300 to transfer the third sample container 20 loaded with the blood sample 30 and having been centrifugally stratified into an upper layer liquid 31, an intermediate layer liquid 32, and a lower layer liquid 33 to the second shooting position; control the second camera device 700 to perform a second shooting action on the third sample container 20 located at the second shooting position; and control the sample container transfer device 300 to transfer the third sample container 20 after the second shooting action is completed and the upper layer liquid 31 loaded therein has not been measured by the measuring mechanism 230 to the second storage space. The total liquid volume of the blood sample 30 is less than the first threshold value, indicating that the blood sample 30 has an abnormal liquid volume phenomenon. The hematocrit of the blood sample 30 is greater than the second threshold value or less than the third threshold value, indicating that the blood sample 30 has an abnormal hematocrit phenomenon. The hemolysis index of the blood sample 30 is greater than the fourth threshold value, or the icteric index of the blood sample 30 is greater than the fifth threshold value, or the lipemia index of the blood sample 30 is greater than the sixth threshold value, indicating that the blood sample 30 has an abnormal HIL phenomenon. The second storage space is used to recover sample containers 20 with abnormal liquid volume, abnormal hematocrit, and abnormal HIL.Since the total liquid volume of the blood sample 30 is too small, the hematocrit of the blood sample 30 is too large, the hematocrit of the blood sample 30 is too small, the hemolysis index of the blood sample 30 exceeds the standard, the icterus index of the blood sample 30 exceeds the standard, and the lipemia index of the blood sample 30 exceeds the standard, all of these may cause errors in the coagulation test result of the blood sample 30. Therefore, the present embodiment judges whether the total liquid volume of the blood sample 30 is abnormal, whether the hematocrit of the blood sample 30 is abnormal, whether the hemolysis index of the blood sample 30 is abnormal, whether the icterus index of the blood sample 30 is abnormal, and whether the lipemia index of the blood sample 30 is abnormal by taking a full-view image of the blood sample 30. When a blood sample 30 with abnormal liquid volume, abnormal hematocrit, or abnormal HIL enters the sample analysis system 10, the control device 500 controls the sample container transmission The transport device 300 transfers the blood sample 30 after the second camera device 700 completes the second shooting action and has not been measured by the measuring mechanism 230 to the second storage space, that is, the blood sample 30 with abnormal liquid volume, abnormal hematocrit or abnormal HIL phenomenon will not be sent to the measuring mechanism 230, thereby effectively preventing the measuring mechanism 230 from measuring the blood sample 30 with abnormal liquid volume, abnormal hematocrit or abnormal HIL phenomenon, that is, the blood sample 30 with abnormal liquid volume, abnormal hematocrit or abnormal HIL phenomenon is intercepted, at least saving the time for the measuring mechanism 230 to measure the blood sample 30 with abnormal liquid volume, abnormal hematocrit or abnormal HIL phenomenon, thereby helping to improve the sample measurement efficiency of the sample analysis system 10.

[0219] As an embodiment, the control device 500 controls the sample container transfer device 300 to transfer the third sample container 20 loaded with the blood sample 30 and having abnormal liquid volume, abnormal hematocrit or abnormal HIL to a node of the second storage space, which is located after the control device 500 determines that the blood sample 30 loaded in the third sample container 20 has abnormal liquid volume, abnormal hematocrit or abnormal HIL according to the second target image 1012.

[0220] As an implementation method, the second storage space and the first storage space are the same storage space, that is, the second storage space and the first storage space are located in the same area. The blood sample 30 with abnormal liquid volume, the blood sample 30 with abnormal hematocrit, the blood sample 30 with abnormal HIL, and the blood sample 30 with abnormal clot are recycled and processed in the same storage space. Of course, in a specific application, as an alternative implementation method, the second storage space and the first storage space can also be two different storage spaces.

[0221] As an embodiment, when the third sample container 20 loaded with the blood sample 30 and the hematocrit of the blood sample 30 is greater than the second threshold value is placed in the sample management device 100, after controlling the second camera device 700 to perform the second shooting action on the third sample container 20 located at the second shooting position, the control device 500 is further configured to: output a prompt message for indicating that the hematocrit of the blood sample 30 in the third sample container 20 is too high. In a specific application, the second threshold value of the hematocrit being too high can be set in the sample analysis system 10. When the hematocrit of the blood sample 30 is detected to be greater than the second threshold value, the blood sample 30 is intercepted and transferred to the second storage space, and a prompt message of the hematocrit being too high is output, which is conducive to reminding the operator to intervene and process the blood sample 30 with the high hematocrit phenomenon as soon as possible, for example: manually verify whether the blood sample 30 actually has the high hematocrit phenomenon, and when it is determined that the hematocrit phenomenon is too high, the blood sample 30 can be collected from the patient again or the blood sample 30 can be processed to eliminate the high hematocrit phenomenon.

[0222] As an embodiment, when the third sample container 20 loaded with the blood sample 30 and the hematocrit of the blood sample 30 is less than the third threshold value is placed in the sample management device 100, after controlling the second camera device 700 to perform the second shooting action on the third sample container 20 located at the second shooting position, the control device 500 is further configured to: output a prompt message for indicating that the hematocrit of the blood sample 30 in the third sample container 20 is low. In a specific application, the third threshold value for low hematocrit can be set in the sample analysis system 10. When the hematocrit of the blood sample 30 is detected to be less than the third threshold value, the blood sample 30 is intercepted and transferred to the second storage space, and a prompt message for low hematocrit is output, which is conducive to reminding the operator to intervene in the treatment of the blood sample 30 with low hematocrit.

[0223] As an embodiment, the output of the prompt information indicating that the hematocrit of the blood sample 30 in the third sample container 20 is too high or too low is performed after the control device 500 completes the analysis of the second target image 1012 and determines that the blood sample 30 loaded in the third sample container 20 has a phenomenon of too high hematocrit or too low hematocrit. That is, when the third sample container 20 loaded with the blood sample 30 and the hematocrit of the blood sample 30 is greater than the second threshold value, or the hematocrit of the blood sample 30 is less than the third threshold value, is placed in the sample management device 100, after the control device 500 completes the analysis of the second target image 1012 and determines that the hematocrit of the blood sample 30 loaded in the third sample container 20 is greater than the second threshold value, or the hematocrit of the blood sample 30 is less than the third threshold value, the control device 500 is further configured to: output the prompt information indicating that the hematocrit of the blood sample 30 in the third sample container 20 is too high or too low hematocrit.

[0224] As an embodiment, the control device 500 is further configured to: after controlling the sample container transfer device 300 to transfer the third sample container 20 that has completed the second shooting action and has not been measured by the measuring mechanism 230 and has not been loaded with the upper layer liquid 31 to the second storage space, output a prompt message for indicating that the hematocrit of the blood sample 30 in the third sample container 20 is too high or too low. In this way, it is convenient for the operator to quickly process the third sample container 20 loaded with the blood sample 30 with a high or low hematocrit phenomenon according to the prompt message. Of course, in a specific application, outputting the prompt message for indicating that the hematocrit of the blood sample 30 in the third sample container 20 is too high or too low is not limited to being executed after the blood sample 30 with a high or low hematocrit phenomenon is transferred to the second storage space, for example, it can also be executed during the transfer to the second storage space or before the transfer to the second storage space.

[0225] As an embodiment, the output of the prompt information indicating that the hematocrit of the blood sample 30 in the third sample container 20 is too high or too low includes: controlling the first display screen 101 to display the prompt information indicating that the hematocrit of the blood sample 30 in the third sample container 20 is too high or too low.

[0226] As another embodiment, the output of prompt information indicating that the hematocrit of the blood sample 30 in the third sample container 20 is high or low includes: controlling the second display screen to display prompt information indicating that the hematocrit of the blood sample 30 in the third sample container 20 is high or low.

[0227] As another embodiment, the output of the prompt information indicating that the hematocrit of the blood sample 30 in the third sample container 20 is too high or too low includes: transmitting the prompt information indicating that the hematocrit of the blood sample 30 in the third sample container 20 is too high or too low to a laboratory information management system (i.e., a LIS system) that is communicatively connected to the sample analysis system 10.

[0228] As an embodiment, when the third sample container 20 loaded with a blood sample 30 and the hematocrit of the blood sample 30 is greater than the second threshold value is placed in the sample management device 100, after controlling the second camera device 700 to perform a second shooting action on the third sample container 20 located at the second shooting position, the control device 500 is further configured to: output recommended collection amount information for characterizing the blood sample 30 and / or output recommended usage information for characterizing the anticoagulant. In a specific application, when the hematocrit of the blood sample 30 is detected to be greater than the second threshold value, the blood sample 30 is intercepted and transferred to the second storage space, and information for adjusting the collection amount of the blood sample 30 and / or adjusting the usage amount of the anticoagulant is output.

[0229] As an embodiment, when the third sample container 20 loaded with a blood sample 30 and the hematocrit of the blood sample 30 is less than the third threshold value is placed in the sample management device 100, after controlling the second camera device 700 to perform a second shooting action on the third sample container 20 located at the second shooting position, the control device 500 is further configured to: output recommended collection amount information for characterizing the blood sample 30 and / or output recommended usage information for characterizing the anticoagulant. In a specific application, when the hematocrit of the blood sample 30 is detected to be less than the third threshold value, the blood sample 30 is intercepted and transferred to the second storage space, and information for adjusting the collection amount of the blood sample 30 and / or adjusting the usage amount of the anticoagulant is output.

[0230] Specifically, the amount V1 of the anticoagulant used and the nominal collection volume V2 of the blood sample 30 satisfy the following relationship: V1=(100-HCT*100)*V2*0.00185, wherein HCT is the hematocrit, in %. The units of the amount V1 of the anticoagulant used and the collection volume V2 of the blood sample 30 are the same, for example, ml.

[0231] As an embodiment, the recommended usage amount of the anticoagulant in the sample container 20 is 1 / 9 of the nominal collection volume V2 of the blood sample 30, and the recommended collection volume V3 of the blood sample 30 and the nominal collection volume V2 of the blood sample 30 satisfy the following formula: V3 = V2 / (0.00185*(100-HCT*100)*9).

[0232] As an implementation, the second threshold is 55% and the third threshold is 20%. Of course, in specific applications, the second threshold and the third threshold are not limited to this. For example, the second threshold can also be set to be slightly higher than 55%, and the third threshold can also be set to be slightly lower than 20%.

[0233] As an embodiment, the above-mentioned output is used to characterize the recommended collection volume information of the blood sample 30 and / or output is used to characterize the recommended usage information of the anticoagulant, including: controlling the first display screen 101 to display the recommended collection volume information for characterizing the blood sample 30 and / or the recommended usage information for characterizing the anticoagulant.

[0234] As another embodiment, the above-mentioned output is used to characterize the recommended collection volume information of the blood sample 30 and / or output is used to characterize the recommended usage information of the anticoagulant, including: controlling the second display screen to display the recommended collection volume information for characterizing the blood sample 30 and / or output is used to characterize the recommended usage information of the anticoagulant.

[0235] As another embodiment, the above-mentioned output is used to characterize the recommended collection volume information of the blood sample 30 and / or the recommended usage information of the anticoagulant, including: transmitting the recommended collection volume information for characterizing the blood sample 30 and / or the recommended usage information for characterizing the anticoagulant to a laboratory information management system (i.e., LIS system) that is communicatively connected to the sample analysis system 10.

[0236] As an embodiment, the control device 500 is also configured to: after controlling the sample container transfer device 300 to transfer the third sample container 20 after completing the second shooting action and without the upper liquid 31 loaded therein being measured by the measuring mechanism 230 to the second storage space, output the recommended collection volume information for characterizing the blood sample 30 and / or output the recommended usage volume information for characterizing the anticoagulant.

[0237] As an embodiment, the control device 500 is also configured to: after controlling the sample container transfer device 300 to transfer the third sample container 20 that has completed the second shooting action and has not been measured by the measuring mechanism 230 and loaded with the upper layer liquid 31 to the second storage space, output a prompt message for characterizing that the hematocrit of the blood sample 30 in the third sample container 20 is too high or too low, and output a recommended collection volume information for characterizing the blood sample 30 and / or output a recommended usage amount information for characterizing the anticoagulant. For example, when the HCT is high, the prompt message "HCT is high, the recommended blood sample 30 collection volume is V4 ml, or the anticoagulant dosage used is V5 ml" is output. When the HCT is low, the prompt message "HCT is low, the recommended blood sample 30 collection volume is V6 ml, or the anticoagulant dosage used is V7 ml" is output.

[0238] As an implementation manner, the above-mentioned obtaining the total liquid volume of the blood sample 30 in the sample container 20 according to the second target image 1012 includes: obtaining the total liquid level of the blood sample 30 in the sample container 20 according to the second target image 1012, and obtaining the total liquid volume of the blood sample 30 in the sample container 20 according to the total liquid level. The total liquid volume of the blood sample 30 is the liquid volume detection result of the blood sample 30. In this implementation manner, the liquid volume detection method of the blood sample 30 is: firstly obtaining the total liquid level of the blood sample 30 through the full image of the blood sample 30, and then obtaining the total liquid volume of the blood sample 30 according to the total liquid level of the blood sample 30, and the operation method is simple.

[0239] As an embodiment, the above-mentioned obtaining the hematocrit of the blood sample 30 in the sample container 20 according to the second target image 1012 includes: obtaining the total liquid level of the blood sample 30 in the sample container 20 and the height of the lower layer liquid 33 according to the second target image 1012, and obtaining the hematocrit of the blood sample 30 in the sample container 20 according to the total liquid level and the height of the lower layer liquid 33. In this embodiment, the hematocrit detection method of the blood sample 30 is: firstly obtaining the total liquid level of the blood sample 30 and the height of the lower layer liquid 33 through the full image of the blood sample 30, and then obtaining the hematocrit of the blood sample 30 according to the total liquid level and the height of the lower layer liquid 33.

[0240] As an implementation method of obtaining the total liquid volume and the hematocrit according to the total liquid level and the height of the lower layer liquid 33, the above-mentioned obtaining the total liquid volume of the blood sample 30 in the sample container 20 according to the total liquid level includes: obtaining the total liquid volume of the blood sample 30 in the sample container 20 according to the total liquid level and a conversion function pre-stored in the sample analysis system 10, wherein the conversion function is a conversion relationship between the liquid level in the sample container 20 and the volume of the blood sample 30. The above-mentioned obtaining the hematocrit of the blood sample 30 in the sample container 20 according to the total liquid level and the height of the lower layer liquid 33 includes: obtaining the hematocrit of the blood sample 30 in the sample container 20 according to the total liquid level, the height of the lower layer liquid 33 and the conversion function. Specifically, the liquid volume and hematocrit are detected as follows: first, the total liquid level of the blood sample 30 and the height of the lower layer liquid 33 are obtained based on the full image of the blood sample 30, then the total volume (i.e., total liquid volume) of the blood sample 30 is converted based on the total liquid level and the conversion function of the pre-stored sample analysis system 10, then the volume of the lower layer liquid 33 is converted based on the height of the lower layer liquid 33 and the conversion function, and then the hematocrit of the blood sample 30 is obtained based on the total volume of the blood sample 30 and the volume of the lower layer liquid 33, thereby completing the detection of the liquid volume and hematocrit of the blood sample 30. The method of obtaining the total liquid volume and hematocrit of the blood sample 30 in this embodiment is suitable for the case where the sample analysis system 10 uses only one type of sample container 20.

[0241] In specific applications, there are many types of sample containers 20. The shape and size parameters of different types of sample containers 20 will be different. The difference in shape and size of the sample container 20 will affect the accuracy of the conversion result from height to volume, thereby affecting the accuracy of the liquid volume detection result and the hematocrit detection result of the blood sample 30. Among them, the influence of the shape and size of the sample container 20 on the calculation accuracy of the liquid volume in the sample container 20 is mainly reflected in the following points: 1) The inner diameter of the sample container 20 is different, that is, the inner diameters of different sample containers 20 are different, and it is difficult to achieve a unified inner diameter. 2) There is a draft angle when the sample container 20 is manufactured, resulting in inconsistency between the inner diameter of the tube mouth and the tube bottom of the sample container 20; 3) The shape of the bottom of the sample container 20 is a non-standard hemisphere, and it is difficult to model and calculate the volume of the bottom of the sample container 20. It can be seen that due to the irregular shape of the sample container 20, before performing liquid volume detection and hematocrit detection, it is necessary to obtain in advance the conversion relationship between the liquid level height in the sample container 20 of this type and the volume of the blood sample 30 to ensure the accuracy of the conversion result from height to volume.

[0242] In the above scheme, in the process of converting the volume according to the height, the conversion function used is pre-stored in the sample analysis system 10, that is, the conversion function is pre-stored in the sample analysis system 10 before the first blood sample 30 is measured after the sample analysis system 10 is installed, and the user end (the actual occasion for the measurement of the blood sample 30, such as the testing room of the hospital) does not need to execute any process to obtain the conversion function. Of course, in a specific application, as an alternative implementation, the conversion function can also be obtained according to the conversion function calibration process, that is, in this alternative implementation, according to the total liquid level, the total liquid volume of the blood sample 30 in the sample container 20 is obtained, including: according to the total liquid level and the conversion function obtained according to the conversion function calibration process, the total liquid volume of the blood sample 30 in the sample container 20 is obtained. The above-mentioned hematocrit of the blood sample 30 in the sample container 20 is obtained according to the total liquid level and the height of the lower layer liquid 33, including: according to the total liquid level, the height of the lower layer liquid 33 and the conversion function obtained according to the conversion function calibration process, the hematocrit of the blood sample 30 in the sample container 20 is obtained. In this alternative embodiment, after the sample analysis system 10 is installed, a conversion function is pre-stored in the sample analysis system 10 . During use at the user end, an updated conversion function is obtained by further executing a conversion function calibration process at the user end.

[0243] As another embodiment of obtaining the total liquid volume and the hematocrit according to the total liquid level and the height of the lower liquid 33, the above-mentioned obtaining the total liquid volume of the blood sample 30 in the sample container 20 according to the total liquid level includes: obtaining a conversion function pre-stored in the sample analysis system 10 and corresponding to the type of the sample container 20 according to the type of the sample container 20, and obtaining the total liquid volume of the blood sample 30 in the sample container 20 according to the total liquid level and the conversion function, wherein the conversion function is a conversion relationship between the liquid level in the sample container 20 and the volume of the blood sample 30. Obtaining the hematocrit of the blood sample 30 in the sample container 20 according to the total liquid level and the height of the lower liquid 33 includes: obtaining the hematocrit of the blood sample 30 in the sample container 20 according to the total liquid level, the height of the lower liquid 33 and the conversion function. The method of obtaining the liquid volume detection result and the hematocrit detection result in this embodiment is applicable to the case where the sample analysis system 10 uses at least two types of sample containers 20. In the related art prior to the present application, it is difficult to measure the inner diameters of all sample containers 20, which makes it difficult to accurately calculate the liquid volume and hematocrit of the blood sample 30 in each different type of sample container 20 according to the liquid level. In this embodiment, the conversion functions corresponding to the different types of sample containers 20 are pre-stored in the sample analysis system 10 in advance. In this way, in a specific application, only the type information of the sample container 20 and the liquid level of the blood sample 30 in the sample container 20 need to be obtained, and the total liquid volume and hematocrit of the blood sample 30 can be converted according to the conversion function. Among them, the type of the sample container 20 can be obtained by a barcode reader or visual shooting, or by loading different types of sample containers 20 separately in different loading areas.

[0244] In the above embodiment, in the process of converting the height to obtain the volume, the conversion function used is pre-stored in the sample analysis system 10. Of course, in a specific application, as an alternative embodiment, the conversion function can also be obtained according to the conversion function calibration process, that is, in this alternative embodiment, the above-mentioned information for characterizing the liquid volume detection result of the blood sample 30 in the sample container 20 according to the total liquid level height includes: according to the type of the sample container 20, a conversion function obtained according to the conversion function calibration process and corresponding to the type of the sample container 20 is obtained, and according to the total liquid level and the conversion function, the information for characterizing the liquid volume detection result of the blood sample 30 in the sample container 20 is obtained. The above-mentioned hematocrit of the blood sample 30 in the sample container 20 according to the total liquid level and the height of the lower layer liquid 33 includes: according to the total liquid level, the height of the lower layer liquid 33 and the conversion function obtained according to the conversion function calibration process and corresponding to the type of the sample container 20, the hematocrit of the blood sample 30 in the sample container 20 is obtained. In this alternative embodiment, after the sample analysis system 10 is installed, the conversion function will be pre-stored in the sample analysis system 10 , and during use at the user end, an updated conversion function will be obtained by further executing a conversion function calibration process at the user end.

[0245] As another embodiment of obtaining the total liquid volume and the hematocrit according to the total liquid level and the height of the lower layer liquid 33, the above-mentioned obtaining the total liquid volume of the blood sample 30 in the sample container 20 according to the total liquid level includes: obtaining the size parameters of the sample container 20 according to the instruction input by the operator through the human-computer interaction device; obtaining the total liquid volume of the blood sample 30 in the sample container 20 according to the total liquid level and the size parameters; the above-mentioned obtaining the hematocrit of the blood sample 30 in the sample container 20 according to the total liquid level and the height of the lower layer liquid 33 includes: obtaining the hematocrit of the blood sample 30 in the sample container 20 according to the total liquid level, the height of the lower layer liquid 33 and the size parameters. In this embodiment, the size parameters of the sample container 20 are obtained by manual input, and the control device 500 can obtain the liquid volume detection result and the hematocrit detection result of the blood sample 30 according to the liquid level obtained by shooting and the manually input size parameters of the sample container 20. It is not necessary to pre-store a conversion function between the liquid level in the sample container 20 and the volume of the blood sample 30 and to set a conversion function calibration process in the sample analysis system 10 .

[0246] As an implementation method of setting up the first storage space, the sample management device 100 is provided with a loading area, a recovery area and a first abnormal area. The loading area is used for placing the sample container 20 to realize the loading of the sample container 20. The recovery area is used for placing the sample container 20 that has been measured by the sample measuring device 200 and the measurement result of the blood sample 30 loaded therein is determined to be normal to realize the recovery of the sample container 20. The first abnormal area is used to store at least the sample container 20 with abnormal code scanning, the sample container 20 with abnormal measurement result of the blood sample 30 loaded therein that has been measured by the sample measuring device 200 and the measurement result of the blood sample 30 loaded therein is determined to be abnormal, and the sample container 20 with abnormal clot phenomenon in the blood sample 30 loaded therein determined by taking an image by the first camera device 400. The first storage space is located in the first abnormal area. In this embodiment, the first abnormal area in the sample management device 100 for storing sample containers 20 with abnormal code scanning and sample containers 20 with abnormal blood samples 30 measured by the sample measuring device 200 is reused as the first storage space to store sample containers 20 with abnormal clots in the blood samples 30 taken by the first camera device 400. In this way, there is no need to set up other structures to form the first storage space, and the structure is simple. As a further embodiment, the second storage space can also be located in the first abnormal area.

[0247] Alternatively, as another embodiment of the first storage space setting method, the sample management device 100 is provided with a loading area, a recovery area, a first abnormal area and a second abnormal area. The loading area is used for placing the sample container 20 to realize the loading of the sample container 20. The recovery area is used to place the sample container 20 that has been measured by the sample measuring device 200 and the measurement result of the blood sample 30 loaded therein is determined to be normal to realize the recovery of the sample container 20. The first abnormal area is used to store the sample container 20 with abnormal code scanning and the sample container 20 that has been measured by the sample measuring device 200 and the measurement result of the blood sample 30 loaded therein is determined to be abnormal. The second abnormal area is used to place the sample container 20 that has been measured by the first camera device 400 and the blood sample 30 loaded therein is determined to have abnormal clot phenomenon. The first storage space is located in the second abnormal area. In this embodiment, a second abnormal area is separately set in the sample management device 100 as the first storage space to store the sample container 20 whose blood sample 30 is determined to have abnormal clot phenomenon after the first camera device 400 takes an image, instead of directly using the first abnormal area in the sample management device 100 for storing the sample container 20 with abnormal code scanning and the sample container 20 with abnormal blood sample 30 after the sample measurement device 200 has completed the measurement, which is conducive to the zoning management of different abnormal sample containers 20. As a further embodiment, the second storage space is located in the first abnormal area or the second abnormal area or an area different from the first abnormal area and different from the second abnormal area.

[0248] Alternatively, as another embodiment of the first storage space setting method, the sample management device 100 is provided with a loading area, a recovery area, a first abnormal area, a second abnormal area and a third abnormal area. The loading area is used for placing the sample container 20 to realize the loading of the sample container 20. The recovery area is used to place the sample container 20 that has been measured by the sample measuring device 200 and the measurement result of the blood sample 30 loaded therein is determined to be normal to realize the recovery of the sample container 20. The first abnormal area is used to store the sample container 20 with abnormal code scanning. The second abnormal area is used to place the sample container 20 with abnormal clot phenomenon in the blood sample 30 loaded therein determined by the first camera device 400. The third abnormal area is used to place the sample container 20 that has been measured by the sample measuring device 200 and the measurement result of the blood sample 30 loaded therein is determined to be abnormal. The first storage space is located in the second abnormal area. In this embodiment, a second abnormal area is separately set in the sample management device 100 as the first storage space to store sample containers 20 whose blood samples 30 are judged to have abnormal clot phenomenon by the first camera device 400, and sample containers 20 with abnormal code scanning and sample containers 20 with abnormal blood samples 30 are also placed in different areas, which is conducive to further refinement of the zoning management of different abnormal sample containers 20. As a further embodiment, the second storage space is located in the first abnormal area, the second abnormal area, the third abnormal area, or an area different from the first abnormal area, the second abnormal area, and the third abnormal area.

[0249] Alternatively, as another embodiment of the first storage space setting method, the sample management device 100 is provided with a loading area, a recovery area and a first abnormal area. The loading area is used for placing the sample container 20 to realize the loading of the sample container 20. The recovery area is used to place the sample container 20 that has been measured by the sample measuring device 200 and the measurement result of the blood sample 30 loaded therein is determined to be normal to realize the recovery of the sample container 20. The first abnormal area is at least used to store the sample container 20 with abnormal code scanning and the sample container 20 with abnormal measurement result of the blood sample 30 loaded therein that has been measured by the sample measuring device 200. The sample analysis system 10 also includes a recovery container, which is located outside the sample management device 100, and the recovery container is located beside, below or above the sample container transmission device 300. The recovery container is used to place the sample container 20 whose blood sample 30 loaded therein is determined to have abnormal clot phenomenon after the first camera device 400 takes an image, and the first storage space is located in the recovery container. In this embodiment, a recovery container is additionally provided outside the sample management device 100 to form a first storage space, so that the recovery and processing of the blood sample 30 with abnormal clotting phenomenon will not affect the sample management device 100. As a further embodiment, the second storage space is located in the first abnormal area or the recovery container or an area different from the first abnormal area and different from the recovery container.

[0250] As an embodiment, the sample container transmission device 300 includes a conveying track 310, a first sample container scheduling mechanism 320 and a sample container transfer device 330. The conveying track 310 is used to convey a sample seat having a single first container position, and the first container position is used to place a single sample container 20; the first sample container scheduling mechanism 320 is used to schedule the sample container 20 placed in the sample management device 100 and loaded with a blood sample 30 to the sample seat located on the conveying track 310.

[0251] As an embodiment, the sample container transfer device 330 is disposed between the conveying track 310 and the sample measuring device 200, and is used to grab the sample containers 20 on the sample holder conveyed by the conveying track 310 one by one to the sample rack inside the sample container transfer device 330, and then send the sample containers 20 to the sample measuring device 200 through the sample rack for measurement. The conveying track 310 is the main conveying track 310 of the sample analysis system 10, and the sample measuring device 200 is a sample processing device in the sample analysis system 10 for performing an analysis function on the blood sample 30. The sample container transfer device 330 is also called an RBU module, which is mainly used to grab the sample containers 20 on the sample holder conveyed by the conveying track 310 one by one to the sample rack inside the sample container transfer device 330, and then send the sample containers 20 to the sample measuring device 200 through the sample rack for measurement. In this embodiment, by setting up the sample container transfer device 330, the effect of transferring the sample container 20 from the sample seat to the sample rack for transmission is achieved, so that the blood sample 30 transmission function between the conveying track 310 with the sample seat conveying function and the sample measuring device 200 with the sample rack conveying function can be realized without changing the structure of the conveying track 310 and the sample measuring device 200.

[0252] As an embodiment, the sample container transfer device 330 includes a sample seat scheduling mechanism, a second sample container scheduling mechanism and a sample rack scheduling mechanism. The sample seat scheduling mechanism is at least used to transfer the sample seat transferred by the conveying track 310 to the sample container transfer device 330 to the rack position. The second sample container scheduling mechanism is used to schedule the sample container 20 on the sample seat at the rack position to the sample rack provided by the sample rack scheduling mechanism. The sample rack has at least two second container positions, each of which is used to place a single sample container 20. The sample rack scheduling mechanism is used to schedule the sample rack loaded with the sample container 20 and the blood sample 30 in the sample container 20 to the sample measurement device 200. The sample seat is a transmission carrier of a single sample container 20, and the sample rack is a transmission carrier of multiple sample containers 20. The sample seat scheduling mechanism is used to realize the connection between the sample container transfer device 330 and the conveying track 310 on the one hand, and to realize the transmission of the sample seat in the sample container transfer device 330 on the other hand. The sample rack scheduling mechanism is used to realize the connection between the sample container transfer device 330 and the sample measurement device 200, and to realize the transfer of the sample rack in the sample container transfer device 330. The second sample container scheduling mechanism is used to realize the interaction between the sample seat scheduling mechanism and the sample rack scheduling mechanism, and to realize the transfer of the sample container 20 between the sample seat and the sample rack.

[0253] As an embodiment, the sample analysis system 10 further includes a centrifugal device 900. The centrifugal device 900 is used to centrifuge the sample container 20 loaded with the blood sample 30 so that the blood sample 30 is centrifugally layered into an upper layer of liquid 31, an intermediate layer of liquid 32, and a lower layer of liquid 33. The sample management device 100 is used to allow the sample container 20 loaded with the blood sample 30 and not subjected to the centrifugal operation to be placed therein so as to load the uncentrifuged blood sample 30, and to allow the sample container 20 loaded with the blood sample 30 and subjected to the centrifugal operation to be placed therein so as to load the centrifuged blood sample 30. The sample container transfer device 300 is at least used to transfer the sample container 20 outputted from the sample management device 100 and loaded with the uncentrifuged blood sample 30 to the centrifugal device 900 for centrifugation, to transfer the sample container 20 outputted from the centrifugal device 900 and loaded with the centrifuged blood sample 30 to the sample measurement device 200, and to transfer the sample container 20 outputted from the sample management device 100 and loaded with the centrifuged blood sample 30 to the sample measurement device 200. In this embodiment, the sample analysis system 10 has the function of centrifuging the blood sample 30, which can meet the sample loading and measurement requirements of uncentrifuged samples and centrifuged samples. Of course, in specific applications, as an alternative implementation, the sample analysis system 10 is also possible without the centrifugation device 900, and the blood sample 30 is placed on the sample analysis system 10 for measurement after the centrifugation of other devices is completed.

[0254] As an implementation of the location of the first camera device 400, the first shooting position is located in the sample container transfer device 330. The first shooting position is located on the path of the sample container transfer device 330 to transfer the sample container 20 and is located between the conveying track 310 and the sample measurement device 200. The first camera device 400 is used to perform a first shooting action on the sample container 20 transferred to the first shooting position by the sample container transfer device 330. In this implementation, the first camera device 400 is provided in the sample container transfer device 330 (i.e., the RBU module) to perform a first shooting action on the sample container 20 in the sample container transfer device 330.

[0255] As another embodiment of the position of the first camera device 400, the first shooting position is located on the conveying track 310. The first shooting position is located on the path of the conveying track 310 for conveying the sample container 20 and is located between the first sample scheduling mechanism and the sample container transfer device 330. The first camera device 400 is used to perform a first shooting action on the sample container 20 conveyed to the first shooting position by the conveying track 310. In this alternative embodiment, the first camera device 400 is provided on the conveying track 310 to perform a first shooting action on the sample container 20 on the conveying track 310.

[0256] As another embodiment of the position of the first camera device 400, the first shooting position is located in the sample measuring device 200, the first shooting position is located on the path of the sample measuring device 200 for conveying the sample container 20 and is located before the sample aspirating position of the sample dispensing mechanism 220, and the first camera device 400 is used to perform a first shooting action on the sample container 20 conveyed to the first shooting position by the sample measuring device 200. In this alternative embodiment, the first camera device 400 is provided in the sample measuring device 200 to perform a first shooting action on the sample container 20 before the sample is aspirated in the sample measuring device 200. Further, a sample aspirating channel 210 for conveying a sample rack is provided in the sample measuring device 200, and the first shooting position and the sample aspirating position are arranged at intervals in the sample aspirating channel 210.

[0257] As another embodiment of the setting position of the first camera device 400, in a scenario where the sample analysis system 10 includes a centrifuge 900, the first shooting position is set on the path where the sample container transmission device 300 transports the sample container 20 from the sample management device 100 to the sample measuring device 200 and is located between the centrifuge 900 and the sample measuring device 200. The first camera device 400 is used to perform a first shooting action on the sample container 20 transported by the sample container transmission device 300 to the first shooting position. Of course, in the scenario where the sample analysis system 10 includes the centrifuge 900, the setting position of the first camera device 400 is not limited thereto. For example, the first camera device 400 can also be used to perform a first shooting action on the sample container 20 that is transported by the sample measuring device 200 to the first shooting position. The first shooting position is located in the sample measuring device 200. The first shooting position is located on the path for the sample measuring device 200 to transport the sample container 20 and is located before the sample suction position of the sample measuring device 200. Alternatively, the first camera device 400 can also be used to perform a first shooting action on the sample container 20 that is transferred from the sample container transfer device 330 to the first shooting position. The first shooting position is located in the sample container transfer device 330. The first shooting position is located on the path for the sample container transfer device 330 to transfer the sample container 20 and is located between the conveying track 310 and the sample measuring device 200.

[0258] As an embodiment, the second camera device 700 is used to perform a second shooting action on the sample container 20 transported by the conveying track 310 to the second shooting position. The second shooting position is located on the conveying track 310. The second shooting position is arranged on the path of the conveying track 310 to transport the sample container 20 and is located between the first sample scheduling mechanism and the sample container transfer device 330.

[0259] As an implementation manner, the second photographing position is located between the centrifugal device 900 and the sample measuring device 200 .

[0260] As an implementation manner, the second shooting position is located between the centrifugal device 900 and the sample container transfer device 330 .

[0261] As an implementation manner, the second camera device 700 is disposed in the sample container transport device 300 and is located beside the centrifugal device 900 .

[0262] As an embodiment, the sample measuring device 200 includes a sample dispensing mechanism 220, a reagent dispensing mechanism 250, an incubation mechanism 240 and a measuring mechanism 230. The sample dispensing mechanism 220 is used to draw a blood sample 30 from the sample container 20 and distribute at least a portion of the drawn blood sample 30 to a reaction container. The reagent dispensing mechanism 250 is used to draw a reagent from a reagent container and distribute at least a portion of the drawn reagent to a reaction container. The incubation mechanism 240 is used to incubate the blood sample 30 or a mixture of the sample and the reagent in the reaction container. The measuring mechanism 230 is used to measure the reaction solution made of the blood sample 30 and the reagent in the reaction container.

[0263] As an embodiment, the sample dispensing mechanism 220 includes a sample needle, a first suction and discharge driving component, and a first motion driving component; the sample needle is used to absorb and discharge the sample. The first suction and discharge driving component is used to provide driving force for the sample needle to absorb and discharge the sample. The first motion driving component is used to drive the sample needle to move in two-dimensional or three-dimensional space, so that the sample needle moves to different positions, such as the standby position, the sample suction position, the sample addition position, the cleaning position, etc.

[0264] As an embodiment, the first suction and discharge driving component is a syringe. Of course, in specific applications, the configuration of the first suction and discharge driving component is not limited thereto, and for example, it can also be a pump or a positive and negative pressure driving component.

[0265] As an embodiment, the sample measuring device 200 further includes a reaction container supply mechanism 270 and a reaction container transport mechanism 280. The reaction container supply mechanism 270 is used to provide a reaction container; and the reaction container transport mechanism 280 is used to transfer the reaction container. In the specific measuring process, the sample dispensing mechanism 220 distributes the blood sample 30 to the reaction container supplied by the reaction container supply mechanism 270, and the reaction container transport mechanism 280 transfers the reaction container provided by the reaction container supply mechanism 270 and completed with the sample to the incubation mechanism 240, and the reagent dispensing mechanism 250 distributes the reagent to the reaction container, and the measuring mechanism 230 measures the reaction made by the blood sample 30 and the reagent in the reaction container, and the reaction container transport mechanism 280 discards and recycles the reaction container after the measurement is completed. In this embodiment, the reaction container is a disposable container, that is, the reaction container is discarded and recycled after carrying the blood sample 30 to complete the measurement of the corresponding measurement item, without the need to be cleaned and reused in the sample measuring device 200, thereby simplifying the structure and working procedures of the sample measuring device 200. Of course, in specific applications, the sample measuring device 200 can also use a recyclable reaction container.

[0266] As an embodiment, the sample measuring device 200 is used to perform coagulation-related detection items on the upper layer liquid 31 distributed into the reaction container. The sample measuring device 200 is a coagulation analyzer, and the reagent dispensing mechanism 250 includes a mixed reagent dispensing component 251 and a trigger reagent dispensing component 252. The mixed reagent dispensing component 251 is used to draw mixed reagent from the mixed reagent container and distribute it to the reaction container, and the trigger reagent dispensing component 252 is used to draw trigger reagent from the trigger reagent container and distribute it to the reaction container. Each coagulation detection item includes at least a sample loading period, an incubation period, a trigger reagent period and a measurement period that are performed in sequence. Among them, during the sample loading period, the sample dispensing mechanism 220 draws blood sample 30 from the sample container 20 and distributes it to the reaction container to complete the sample loading operation. During the incubation period of the multi-reagent coagulation measurement item, the mixed reagent dispensing component 251 draws mixed reagent from the reagent container and distributes it to the reaction container, and the incubation mechanism 240 incubates the reaction container loaded with at least the blood sample 30 and the mixed reagent to complete the incubation operation of the multi-reagent coagulation measurement item. During the incubation period of the single-reagent coagulation assay, the incubation mechanism 240 incubates the reaction container loaded with at least the blood sample 30 to complete the incubation operation of the single-reagent coagulation assay. During the trigger reagent period, the trigger reagent dispensing component 252 draws the trigger reagent from the reagent container and distributes it to the reaction container, and mixes the reaction container to complete the trigger reagent addition operation. During the measurement period, the measurement mechanism 230 measures the reaction liquid in the reaction container to complete the measurement operation. Of course, in specific applications, the sample measurement device 200 is not limited to a coagulation analyzer. For example, as an alternative embodiment, the sample measurement device 200 can also be a biochemical analyzer, an immunoassay analyzer, etc.

[0267] As an embodiment, the processing process of the blood sample 30 used in the determination of coagulation items includes: using sodium citrate as an anticoagulant, mixing the anticoagulant and the blood sample 30 thoroughly, and then centrifuging on a centrifuge 900; due to the different densities of red blood cells, white blood cells, platelets and plasma, the blood sample 30 after centrifugation is divided into three layers, the bottom layer is mainly red blood cells; the top layer is plasma, which is light yellow; between the red blood cells and plasma is a white film layer, the main components of which are white blood cells and platelets; the determination of coagulation items mainly involves the absorption and analysis of the plasma above, and the plasma used for the determination of coagulation items is also called platelet-poor plasma.

[0268] In a preferred embodiment, the sample analysis system 10 mainly adopts an optical photography method to take photos of the whole image and the white film layer of the centrifuged blood sample 30, and uses the whole image information of the blood sample 30 to calculate the liquid volume detection result, HCT detection result and HIL detection result of the blood sample 30, and uses the white film layer photography method to obtain the clot detection result of the blood sample 30. In this way, the clot of the blood sample 30 is pre-checked, and the blood sample 30 suspected of having abnormal clot phenomenon is intercepted and transported to a designated area (i.e., the first storage space) so that it does not enter the sample measurement device 200 (e.g., a coagulation analyzer) for measurement. In addition, in a further scheme, the total liquid volume, HIL, and HCT can also be pre-checked, and the blood sample 30 with abnormal total liquid volume, abnormal HIL, and abnormal HCT can be intercepted and transported to a designated area (i.e., the second storage space) so that it does not enter the sample measurement device 200 for measurement.

[0269] The second aspect of the embodiment of the present invention provides a sample analysis system 10, which differs from the sample analysis system 10 provided by the first aspect of the embodiment of the present invention mainly in that: under the premise of intercepting the blood sample 30 with abnormal clotting phenomenon, the first aspect focuses on limiting the possible setting method of the first storage space; while the second aspect focuses on limiting the transmission of blood samples 30 with abnormal clotting phenomenon and blood samples 30 without abnormal clotting phenomenon along different routes.

[0270] Specifically, the sample analysis system 10 provided in the second aspect of the embodiment of the present invention includes a sample management device 100, a sample measurement device 200, a sample container transmission device 300, a first camera device 400 and a control device 500. The sample management device 100 is at least used for placing the sample container 20 loaded with the blood sample 30 to achieve the loading of the blood sample 30. The sample measurement device 200 includes a sample distribution mechanism 220 and a measurement mechanism 230. The sample distribution mechanism 220 is used to absorb at least part of the upper layer liquid 31 from the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and separated into the upper layer liquid 31, the middle layer liquid 32 and the lower layer liquid 33, and distribute it to the reaction container. The middle layer liquid 32 contains platelets and / or leukocytes. The measurement mechanism 230 is used to measure the liquid to be tested in the reaction container made of at least the absorbed upper layer liquid 31 and the reagent. The sample container transmission device 300 is used to transfer the sample container 20 loaded with the blood sample 30 from the sample management device 100 to the sample measurement device 200. The first camera device 400 is used to perform a first photographing operation on the sample container 20 from obliquely above or below the intermediate layer liquid 32 loaded in the sample container 20 before the sample dispensing mechanism 220 sucks the upper layer liquid 31 from the sample container 20 .The control device 500 is configured as follows: when a first sample container 20 loaded with a blood sample 30 and having a clot abnormality is placed in the sample management device 100, the control device 500 controls the sample container transfer device 300 to transfer the first sample container 20 loaded with a blood sample 30 and having the blood sample 30 separated into an upper layer liquid 31, a middle layer liquid 32, and a lower layer liquid 33 after centrifugation to the first shooting position, controls the first camera device 400 to perform a first shooting action on the first sample container 20 located at the first shooting position, controls the sample container transfer device 300 to transfer the first sample container 20 loaded with the upper layer liquid 31 after the first shooting action is completed and has not been measured by the measuring mechanism 230 to the first storage space along the first route; when a second sample container 20 loaded with a blood sample 30 and having no clot abnormality is placed in the sample management device 100, the control device 500 controls the sample container transfer device 300 to transfer the first sample container 20 loaded with the blood sample 30 and having no clot abnormality after centrifugation to the first shooting position; The sample container is placed in the sample management device 100, controls the sample container transmission device 300 to transmit the second sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and separated into an upper layer liquid 31, a middle layer liquid 32, and a lower layer liquid 33 to the first shooting position, controls the first camera device 400 to perform a first shooting action on the second sample container 20 located at the first shooting position, controls the sample container transmission device 300 to transmit the second sample container 20 after the first shooting action is completed to the sample measurement device 200 along the second route, controls the sample distribution mechanism 220 to absorb at least part of the upper layer liquid 31 from the second sample container 20 and distribute it to the first reaction container, and controls the measurement mechanism 230 to measure the first test liquid prepared by at least the upper layer liquid 31 distributed to the first reaction container and the reagent; wherein the first route and the second route are at least partially different.

[0271] As an embodiment, when a first sample container 20 loaded with a blood sample 30 and having an abnormal clotting phenomenon in the blood sample 30 is placed in the sample management device 100, after controlling the first camera device 400 to perform a first shooting action on the first sample container 20 located at a first shooting position, the control device 500 is further configured to: output prompt information for indicating that the blood sample 30 in the first sample container 20 has an abnormal clotting phenomenon.

[0272] As an embodiment, after controlling the sample container transmission device 300 to transmit the first sample container 20 along the first route to the first storage space after completing the first shooting action and without the upper liquid 31 loaded therein being measured by the measuring mechanism 230, the control device 500 is also configured to: output a prompt message for characterizing the presence of an abnormal clot phenomenon in the blood sample 30 in the first sample container 20.

[0273] As an embodiment, controlling the sample container transmission device 300 to transmit the first sample container 20 that has completed the first shooting action and has not yet been measured by the measuring mechanism 230 to the first storage space along the first route includes: according to the first target image 1011 obtained by the first camera device 400 performing the first shooting action on the first sample container 20 located at the first shooting position, controlling the sample container transmission device 300 to transmit the first sample container 20 that has completed the first shooting action and has not yet been measured by the measuring mechanism 230 to the first storage space along the first route; wherein there is a boundary liquid surface 321 or a boundary liquid layer between the intermediate layer liquid 32 and the upper layer liquid 31; the first target image 1011 at least includes an image showing the boundary liquid surface 321 or the boundary liquid layer in a two-dimensional form and / or a three-dimensional form.

[0274] In addition to the above, other parts and principles of the sample analysis system 10 provided in the second aspect of the embodiment of the present invention can refer to the above first aspect and will not be described in detail here.

[0275] The third aspect of the embodiment of the present invention provides a sample analysis system 10, which differs from the sample analysis system 10 provided in the first aspect of the embodiment of the present invention mentioned above mainly in that: under the premise of intercepting the blood sample 30 with abnormal clotting phenomenon, the first aspect focuses on limiting the possible setting method of the first storage space; while the second aspect focuses on limiting the first camera device 400 to perform a first shooting action on the sample container 20 from obliquely above or obliquely below the middle layer liquid 32 in the sample container 20.

[0276] Specifically, the sample analysis system 10 provided in the second aspect of the embodiment of the present invention includes a sample management device 100, a sample measurement device 200, a sample container transmission device 300, a first camera device 400 and a control device 500. The sample management device 100 is at least used for placing the sample container 20 loaded with the blood sample 30 to achieve the loading of the blood sample 30. The sample measurement device 200 includes a sample distribution mechanism 220 and a measurement mechanism 230. The sample distribution mechanism 220 is used to absorb at least part of the upper layer liquid 31 from the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and separated into the upper layer liquid 31, the middle layer liquid 32 and the lower layer liquid 33, and distribute it to the reaction container. The middle layer liquid 32 contains platelets and / or leukocytes. The measurement mechanism 230 is used to measure the liquid to be tested in the reaction container made of at least the absorbed upper layer liquid 31 and the reagent. The sample container transmission device 300 is used to transfer the sample container 20 loaded with the blood sample 30 from the sample management device 100 to the sample measurement device 200. The first camera device 400 is used to perform a first photographing operation on the sample container 20 from obliquely above or below the intermediate layer liquid 32 loaded in the sample container 20 before the sample dispensing mechanism 220 sucks the upper layer liquid 31 from the sample container 20 .The control device 500 is configured to: when the first sample container 20 loaded with the blood sample 30 and in which the blood sample 30 has a coagulation abnormality is placed in the sample management device 100, control the sample container transfer device 300 to transfer the first sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and separated into an upper layer liquid 31, an intermediate layer liquid 32, and a lower layer liquid 33 to the first shooting position, control the first camera device 400 to perform a first shooting action on the first sample container 20 located at the first shooting position, control the sample container transfer device 300 to transfer the first sample container 20 after the first shooting action is completed and the upper layer liquid 31 loaded therein has not been measured by the measuring mechanism 230 to the first storage space, and output a prompt message for indicating that the blood sample 30 in the first sample container 20 has a coagulation abnormality; when the first sample container 20 loaded with the blood sample 30 is placed in the sample management device 100, control the sample container transfer device 300 to transfer the first sample container 20 after the first shooting action is completed and the upper layer liquid 31 loaded therein has not been measured by the measuring mechanism 230 to the first storage space, and output a prompt message for indicating that the blood sample 30 in the first sample container 20 has a coagulation abnormality; The second sample container 20 containing the blood sample 30 and having no abnormal clot phenomenon in the blood sample 30 is placed in the sample management device 100, the sample container transfer device 300 is controlled to transfer the second sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and separated into an upper layer liquid 31, a middle layer liquid 32, and a lower layer liquid 33 to the first shooting position, the first camera device 400 is controlled to perform a first shooting action on the second sample container 20 located at the first shooting position, the sample container transfer device 300 is controlled to transfer the second sample container 20 after the first shooting action is completed to the sample measurement device 200, the sample distribution mechanism 220 is controlled to absorb at least a part of the upper layer liquid 31 from the second sample container 20 and distribute it to the first reaction container, and the measurement mechanism 230 is controlled to measure the first test liquid prepared by at least the upper layer liquid 31 distributed to the first reaction container and the reagent.

[0277] As an embodiment, the sample analysis system 10 also includes a first display screen 101. The first display screen 101 and the sample measuring device 200 are independently arranged. The first display screen 101 is at least used to display the storage information of the blood sample 30 in the sample management device 100 and the information of the blood sample 30 transmitted by the sample container transmission device 300. The output of the prompt information for indicating that the blood sample 30 in the first sample container 20 has an abnormal clotting phenomenon includes: controlling the first display screen 101 to display the prompt information for indicating that the blood sample 30 in the first sample container 20 has an abnormal clotting phenomenon.

[0278] As an embodiment, the sample measuring device 200 also includes a second display screen, which is used to display at least the measuring item information of the blood sample 30 in the sample measuring device 200. Outputting the prompt information indicating that the blood sample 30 in the first sample container 20 has an abnormal clotting phenomenon includes: controlling the second display screen to display the prompt information indicating that the blood sample 30 in the first sample container 20 has an abnormal clotting phenomenon.

[0279] As an embodiment, outputting the prompt information for characterizing the presence of abnormal clotting in the blood sample 30 in the first sample container 20 includes: transmitting the prompt information for characterizing the presence of abnormal clotting in the blood sample 30 in the first sample container 20 to a laboratory information management system that is communicatively connected to the sample analysis system 10.

[0280] As an embodiment, the sample analysis system 10 also includes an alarm device, which includes a sound alarm component and / or a light alarm component, and outputs prompt information for indicating that the blood sample 30 in the first sample container 20 has an abnormal clotting phenomenon, including: controlling the alarm device to emit a sound alarm signal and / or a light alarm signal for indicating that the blood sample 30 in the first sample container 20 has an abnormal clotting phenomenon.

[0281] As an embodiment, controlling the sample container transmission device 300 to transmit the first sample container 20 after completing the first shooting action and before the upper liquid 31 loaded therein is measured by the measuring mechanism 230 to the first storage space includes: according to the first target image 1011 obtained by the first camera device 400 performing the first shooting action on the first sample container 20 located at the first shooting position, controlling the sample container transmission device 300 to transmit the first sample container 20 after completing the first shooting action and before the upper liquid 31 loaded therein is measured by the measuring mechanism 230 to the first storage space; wherein, there is a boundary liquid surface 321 or a boundary liquid layer between the intermediate layer liquid 32 and the upper layer liquid 31; the first target image 1011 at least includes an image showing the boundary liquid surface 321 or the boundary liquid layer in a two-dimensional form and / or a three-dimensional form.

[0282] In addition to the above, other parts and principles of the sample analysis system 10 provided in the third aspect of the embodiment of the present invention can refer to the first aspect above and will not be described in detail here.

[0283] According to a fourth aspect of an embodiment of the present invention, there is provided a control method of a sample analysis system 10, the control method comprising: controlling a sample container transmission device 300 to transmit a sample container 20 loaded with a blood sample 30 and after the blood sample 30 is centrifuged and separated into an upper layer liquid 31, a middle layer liquid 32, and a lower layer liquid 33 to a first shooting position; controlling a first camera device 400 to perform a first shooting action on the sample container 20 located at the first shooting position to obtain a first target image 1011; judging whether there is a clot abnormality in the blood sample 30 loaded in the sample container 20 according to the first target image 1011; if it is judged that there is a clot abnormality in the blood sample 30 loaded in the sample container 20 according to the first target image 1011, then controlling the sample container transmission device 300 to perform a first shooting action on the sample container 20 after the first shooting action is completed and without being subjected to the measuring mechanism 230 of the sample measuring device 200; The sample container 20 in which the upper layer liquid 31 is to be measured is transferred to the first storage space; if it is determined according to the first target image 1011 that the blood sample 30 loaded in the sample container 20 has no abnormal clot phenomenon, the sample container transmission device 300 is controlled to transfer the sample container 20 after the first shooting action to the sample measurement device 200, the sample distribution mechanism 220 of the sample measurement device 200 is controlled to absorb at least part of the upper layer liquid 31 from the sample container 20 and distribute it to the first reaction container, and the measurement mechanism 230 is controlled to measure the first test liquid made of at least the upper layer liquid 31 distributed to the first reaction container and the reagent; wherein there is a boundary liquid surface 321 or a boundary liquid layer between the intermediate layer liquid 32 and the upper layer liquid 31; the first target image 1011 at least includes an image showing the boundary liquid surface 321 or the boundary liquid layer in a two-dimensional form and / or a three-dimensional form.

[0284] As an implementation manner, after determining that the blood sample 30 loaded in the sample container 20 has abnormal clotting phenomenon, the control method further includes: outputting prompt information for indicating that the blood sample 30 in the sample container 20 has abnormal clotting phenomenon.

[0285] As an embodiment, after controlling the sample container transmission device 300 to transfer the sample container 20 that has completed the first shooting action and has not been measured by the measuring mechanism 230 of the sample measuring device 200 and has the upper layer liquid 31 loaded therein to the first storage space, the control method also includes: outputting a prompt message for indicating that there is an abnormal clot phenomenon in the blood sample 30 in the sample container 20.

[0286] As an embodiment, before controlling the sample container transmission device 300 to transmit the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and separated into an upper layer of liquid 31, an intermediate layer of liquid 32, and a lower layer of liquid 33 to the first shooting position, the control method further includes: controlling the sample container transmission device 300 to transmit the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and separated into an upper layer of liquid 31, an intermediate layer of liquid 32, and a lower layer of liquid 33 to the second shooting position; controlling the second camera device 700 to perform a second shooting action on the sample container 20 located at the second shooting position to obtain a second target image 1012; and obtaining at least one of the following information according to the second target image 1012: the total liquid volume of the blood sample 30 in the sample container 20, the hematocrit of the blood sample 30 in the sample container 20, the hemolytic index of the blood sample 30 in the sample container 20, and the hemolysis index of the blood sample 30 in the sample container 20. 0, the lipemia index of the blood sample 30 in the sample container 20; when it is determined according to the second target image 1012 that the blood sample 30 meets at least one of the following conditions: the total liquid volume of the blood sample 30 is less than the first threshold value, or the hematocrit of the blood sample 30 is greater than the second threshold value, or the hematocrit of the blood sample 30 is less than the third threshold value, or the hemolysis index of the blood sample 30 is greater than the fourth threshold value, or the jaundice index of the blood sample 30 is greater than the fifth threshold value, or the lipemia index of the blood sample 30 is greater than the sixth threshold value, the sample container transmission device 300 is controlled to transmit the sample container 20 after the second shooting action is completed and the upper layer liquid 31 loaded therein has not been measured by the measuring mechanism 230 of the sample measuring device 200 to the second storage space; wherein the second storage space and the first storage space are the same storage space, or the second storage space and the first storage space are two different storage spaces.

[0287] In addition to the above, other parts and principles of the control method of the sample analysis system 10 provided in the fourth aspect of the embodiment of the present invention can refer to the first to third aspects mentioned above and will not be described in detail here.

[0288] The above description is only a preferred embodiment of the present invention, and does not limit the patent scope of the present invention. All equivalent structural changes made by using the contents of the present invention specification and drawings under the inventive concept of the present invention, or directly / indirectly applied in other related technical fields are included in the patent protection scope of the present invention.

Claims

1. A sample analysis system, characterized in that: include: A sample management device, the sample management device is at least used for placing a sample container loaded with a blood sample to achieve the loading of the blood sample; A sample measuring device, the sample measuring device comprising a sample dispensing mechanism and a measuring mechanism, the sample dispensing mechanism is used to absorb at least part of the upper layer liquid from the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer liquid, an intermediate layer liquid, and a lower layer liquid, and distribute it to a reaction container, the intermediate layer liquid containing platelets and / or leukocytes; the measuring mechanism is used to measure the test liquid in the reaction container made of at least the absorbed upper layer liquid and a reagent; a sample container transporting device, the sample container transporting device being used to transport the sample container loaded with the blood sample from the sample management device to the sample measuring device; a first camera device, the first camera device being used to perform a first photographing action on the sample container from obliquely above or obliquely below the middle layer liquid loaded in the sample container before the sample dispensing mechanism absorbs the upper layer liquid from the sample container; A control device, the control device being configured to: When a first sample container loaded with the blood sample and having abnormal clots in the blood sample is placed in the sample management device, the sample container transfer device is controlled to transfer the first sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position, the first camera device is controlled to perform the first shooting action on the first sample container located at the first shooting position, and the sample container transfer device is controlled to transfer the first sample container after the first shooting action is completed and the upper layer of liquid loaded therein is not measured by the measuring mechanism to the first storage space; When a second sample container loaded with the blood sample and having no abnormal clot phenomenon in the blood sample is placed in the sample management device, the sample container transmission device is controlled to transmit the second sample container loaded with the blood sample and after the blood sample is centrifuged and stratified into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position, the first camera device is controlled to perform the first shooting action on the second sample container located at the first shooting position, the sample container transmission device is controlled to transmit the second sample container after completing the first shooting action to the sample measurement device, the sample distribution mechanism is controlled to absorb at least a part of the upper layer of liquid from the second sample container and distribute it to the first reaction container, and the measurement mechanism is controlled to measure the first test liquid made of at least the upper layer of liquid distributed to the first reaction container and a reagent; Wherein, the first storage space is located in the sample management device, or is located beside the sample container transmission device, or is located below the sample container transmission device, or is located above the sample container transmission device.

2. The sample analysis system according to claim 1, wherein: The controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space comprises: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the first sample container has not been transported by the sample container transporting device to the sample measuring device to the first storage space; Alternatively, the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space includes: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed to the sample measuring device, and controlling the sample container transporting device to transport the first sample container output from the sample measuring device and the upper layer liquid has not been sucked out of it by the sample dispensing mechanism to the first storage space; Alternatively, the sample measuring device further includes a reagent dispensing mechanism, and the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space comprises: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least part of the upper layer liquid from the first sample container and distribute it to a second reaction container, and controlling the sample container transporting device to transport the first sample container output from the sample measuring device and before the reagent dispensing mechanism distributes the reagent to the second reaction container to the first storage space; Alternatively, the sample measuring device further includes an incubation mechanism, and the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space comprises: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least a portion of the upper layer liquid from the first sample container and distribute it to a second reaction container, and controlling the sample container transporting device to transport the first sample container output from the sample measuring device and without the incubation mechanism incubating the liquid in the second reaction container at least containing the upper layer liquid distributed from the first sample container to the second reaction container to the first storage space; Alternatively, the sample measuring device further includes a reagent dispensing mechanism and an incubation mechanism, and the control of the sample container transmission device to transfer the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space includes: controlling the sample container transmission device to transfer the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least a portion of the upper layer liquid from the first sample container and distribute it to a second reaction container, controlling the incubation mechanism to incubate the liquid in the second reaction container that at least contains the upper layer liquid distributed from the first sample container to the second reaction container, controlling the reagent dispensing mechanism to distribute the reagent to the second reaction container, and controlling the sample container transmission device to transfer the first sample container that is output from the sample measuring device and the second liquid to be tested that at least contains the upper layer liquid distributed to the second reaction container and the reagent has not been measured by the measuring mechanism to the first storage space.

3. The sample analysis system according to claim 1 or 2, characterized in that: When a first sample container loaded with the blood sample and having abnormal clotting phenomenon in the blood sample is placed in the sample management device, after controlling the first camera device to perform the first shooting action on the first sample container located at the first shooting position, the control device is further configured to: output prompt information for indicating that the blood sample in the first sample container has abnormal clotting phenomenon; Preferably, after the sample container transmission device is controlled to transmit the first sample container to the first storage space after completing the first shooting action and without the upper layer liquid loaded therein being measured by the measuring mechanism, the control device is further configured to: output prompt information for characterizing the presence of abnormal clotting phenomenon in the blood sample in the first sample container.

4. The sample analysis system according to claim 3, characterized in that: The sample analysis system further includes a first display screen, the first display screen and the sample measuring device are independently arranged, the first display screen is used to display at least the storage information of the blood sample in the sample management device and the information of the blood sample transmitted by the sample container transmission device, and the outputting the prompt information indicating that the blood sample in the first sample container has a coagulation abnormality includes: controlling the first display screen to display the prompt information indicating that the blood sample in the first sample container has a coagulation abnormality; And / or, the sample measuring device further comprises a second display screen, the second display screen is used to display at least the measuring item information of the blood sample in the sample measuring device, and the outputting of the prompt information indicating that the blood sample in the first sample container has an abnormal clotting phenomenon comprises: controlling the second display screen to display the prompt information indicating that the blood sample in the first sample container has an abnormal clotting phenomenon; And / or, the outputting of the prompt information for indicating that the blood sample in the first sample container has an abnormal clotting phenomenon includes: transmitting the prompt information for indicating that the blood sample in the first sample container has an abnormal clotting phenomenon to a laboratory information management system that is communicatively connected to the sample analysis system; And / or, the sample analysis system also includes an alarm device, the alarm device includes a sound alarm component and / or a light alarm component, and the output is used to indicate that the blood sample in the first sample container has an abnormal clotting phenomenon, including: controlling the alarm device to emit a sound alarm signal and / or a light alarm signal for indicating that the blood sample in the first sample container has an abnormal clotting phenomenon.

5. The sample analysis system according to claim 1, wherein: The controlling the sample container transport device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space comprises: controlling the sample container transport device to transport the first sample container along a first route to the first storage space; The controlling the sample container transport device to transport the second sample container after the first shooting action is completed to the sample measuring device comprises: controlling the sample container transport device to transport the second sample container to the sample measuring device along a second route; The first route is at least partially different from the second route.

6. The sample analysis system according to claim 1, wherein: The controlling of the sample container transmission device to transmit the first sample container after the first shooting action is completed and the upper layer liquid loaded thereon has not been measured by the measuring mechanism to the first storage space includes: based on the image obtained by the first camera device performing the first shooting action on the first sample container located at the first shooting position, controlling the sample container transmission device to transmit the first sample container after the first shooting action is completed and the upper layer liquid loaded thereon has not been measured by the measuring mechanism to the first storage space.

7. The sample analysis system according to claim 6, wherein: The method of controlling the sample container transport device to transport the first sample container located at the first photographing position after the first photographing action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space according to the image obtained by the first camera device performing the first photographing action on the first sample container located at the first photographing position, comprises: Obtaining a first target image according to information fed back by the first camera device performing the first shooting action on the first sample container located at the first shooting position; When it is determined according to the first target image that the blood sample loaded in the first sample container has an abnormal clot phenomenon, the sample container transmission device is controlled to transmit the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space; Preferably, there is a boundary liquid surface or a boundary liquid layer between the intermediate layer liquid and the upper layer liquid; and the first target image at least includes an image showing the boundary liquid surface or the boundary liquid layer in a two-dimensional form and / or a three-dimensional form.

8. The sample analysis system according to claim 7, wherein: The step of determining, based on the first target image, whether the blood sample loaded in the first sample container has an abnormal clot phenomenon includes: Extracting a target index for characterizing the flatness of the intermediate layer liquid in the first target image; comparing the target indicator with a preset indicator; If the target index is greater than or equal to the preset index, it is determined that the blood sample loaded in the first sample container has abnormal clotting phenomenon; Alternatively, determining, based on the first target image, that the blood sample loaded in the first sample container has an abnormal clot phenomenon includes: extracting target features in the first target image; comparing the target feature with a preset feature; If the similarity between the target feature and the preset feature is greater than or equal to a first preset threshold, it is determined that the blood sample loaded in the first sample container has a clot abnormality; Alternatively, determining, based on the first target image, that the blood sample loaded in the first sample container has an abnormal clot phenomenon includes: comparing the first target image with a preset image; If the similarity between the first target image and the preset image is greater than or equal to a second preset threshold, it is determined that the blood sample loaded in the first sample container has a clot abnormality.

9. The sample analysis system according to claim 1, wherein: After controlling the first camera device to perform the first photographing action on the second sample container located at the first photographing position, and before controlling the measuring mechanism to measure the first test liquid prepared by at least the upper layer liquid and the reagent distributed into the first reaction container, the control device is further configured to: Obtaining a first target image according to information fed back by the first camera device performing the first shooting action on the second sample container located at the first shooting position; According to the first target image, determining that the blood sample loaded in the second sample container has no abnormal clot phenomenon; Preferably, there is a boundary liquid surface or a boundary liquid layer between the intermediate layer liquid and the upper layer liquid; and the first target image at least includes an image showing the boundary liquid surface or the boundary liquid layer in a two-dimensional form and / or a three-dimensional form.

10. The sample analysis system according to any one of claims 1 to 9, characterized in that: The sample analysis system further includes a first reflector, the first reflector being used to: reflect the image of the sample container to the first camera device when the first camera device performs the first shooting action; The first camera device performing the first shooting action on the sample container includes: the first camera device shooting an image of the sample container in the first reflector toward the first reflector; Alternatively, the first camera device captures the image of the sample container from obliquely above or obliquely below the intermediate layer of liquid, directly toward the sample container.

11. The sample analysis system according to any one of claims 1 to 9, characterized in that: The sample analysis system further comprises a second camera device, which is used to perform a second photographing action on the sample container before the sample dispensing mechanism absorbs at least a portion of the upper layer of liquid from the sample container; The control device is also configured to: Obtaining a second target image according to information fed back by the second camera device performing the second shooting action; According to the second target image, at least one of the following information is obtained: the total liquid volume of the blood sample in the sample container, the hematocrit of the blood sample in the sample container, the hemolysis index of the blood sample in the sample container, the icterus index of the blood sample in the sample container, and the lipemia index of the blood sample in the sample container; Preferably, the second target image at least includes an image showing the entire height of one side of the sample container in a two-dimensional and / or three-dimensional form, or at least includes an image showing all of the blood samples in the sample container in a two-dimensional and / or three-dimensional form, or at least includes an image showing the liquid level of the upper liquid layer, the liquid level of the middle liquid layer, and the liquid level of the lower liquid layer in the sample container in a two-dimensional and / or three-dimensional form, or at least includes an image showing all of the upper liquid layer, all of the middle liquid layer, and all of the lower liquid layer in the sample container in a two-dimensional and / or three-dimensional form, or at least includes an image showing at least one side of the bottom, middle part, and top of the sample container in a two-dimensional and / or three-dimensional form; The second camera device and the first camera device are two independent camera devices, or the second camera device and the first camera device are the same camera device.

12. The sample analysis system according to claim 11, characterized in that: The control device is also configured to: When a third sample container loaded with a blood sample and having a total liquid volume less than a first threshold, or a hematocrit of the blood sample greater than a second threshold, or a hematocrit of the blood sample less than a third threshold, or a hemolysis index of the blood sample greater than a fourth threshold, or a icteric index of the blood sample greater than a fifth threshold, or a lipemia index of the blood sample greater than a sixth threshold is placed in the sample management device, the sample container transfer device is controlled to transfer the third sample container loaded with the blood sample and having the blood sample centrifugally separated into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the second shooting position; Controlling the second camera device to perform the second shooting action on the third sample container located at the second shooting position; Controlling the sample container transport device to transport the third sample container after the second shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the second storage space; The second storage space and the first storage space are the same storage space, or the second storage space and the first storage space are two different storage spaces.

13. The sample analysis system according to claim 12, wherein: When the third sample container loaded with the blood sample and having a hematocrit greater than the second threshold, or having a hematocrit less than the third threshold, is placed in the sample management device, after controlling the second camera device to perform the second shooting action on the third sample container located at the second shooting position, the control device is further configured to: output prompt information for indicating that the hematocrit of the blood sample in the third sample container is too high or too low; Preferably, the control device is further configured to: after the sample container transport device is controlled to transport the third sample container after the second shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the second storage space, output a prompt message for indicating that the hematocrit of the blood sample in the third sample container is too high or too low; Preferably, the sample analysis system further comprises a first display screen, which is independently arranged from the sample measuring device, and is at least used to display storage information of the blood sample in the sample management device and information of the blood sample transmitted by the sample container transmission device, and the output is used to indicate prompt information that the hematocrit of the blood sample in the third sample container is too high or too low, comprising: controlling the first display screen to display prompt information that the hematocrit of the blood sample in the third sample container is too high or too low.

14. The sample analysis system according to claim 13, wherein: When the third sample container loaded with a blood sample whose hematocrit is greater than the second threshold value, or whose hematocrit is less than the third threshold value, is placed in the sample management device, after controlling the second camera device to perform the second shooting action on the third sample container located at the second shooting position, the control device is further configured to: output recommended collection amount information for characterizing the blood sample and / or output recommended usage amount information for characterizing the anticoagulant; Preferably, the control device is further configured to: after controlling the sample container transport device to transport the third sample container after the second shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the second storage space, output the recommended collection amount information for characterizing the blood sample and / or output the recommended usage amount information for characterizing the anticoagulant; Preferably, the output is used to characterize the recommended collection volume information of the blood sample and / or the output is used to characterize the recommended usage information of the anticoagulant, including: controlling the first display screen to display the recommended collection volume information for characterizing the blood sample and / or the recommended usage information for characterizing the anticoagulant.

15. The sample analysis system according to claim 11, wherein: The step of obtaining the total liquid volume of the blood sample in the sample container according to the second target image comprises: obtaining the total liquid level of the blood sample in the sample container according to the second target image, and obtaining the total liquid volume of the blood sample in the sample container according to the total liquid level; The obtaining of the hematocrit of the blood sample in the sample container according to the second target image comprises: obtaining the total liquid level height of the blood sample in the sample container and the height of the lower layer liquid according to the second target image, and obtaining the hematocrit of the blood sample in the sample container according to the total liquid level height and the height of the lower layer liquid.

16. The sample analysis system according to claim 15, characterized in that: The step of obtaining the total liquid volume of the blood sample in the sample container according to the total liquid level comprises: obtaining the total liquid volume of the blood sample in the sample container according to the total liquid level and a conversion function pre-stored in the sample analysis system or obtained according to a conversion function calibration process, wherein the conversion function is a conversion relationship between the liquid level in the sample container and the volume of the blood sample; The step of obtaining the hematocrit of the blood sample in the sample container according to the total liquid level and the height of the lower layer liquid comprises: obtaining the hematocrit of the blood sample in the sample container according to the total liquid level, the height of the lower layer liquid and the conversion function; Alternatively, obtaining the total liquid volume of the blood sample in the sample container according to the total liquid level includes: obtaining, according to the type of the sample container, a conversion function that is pre-stored in the sample analysis system or obtained according to a conversion function calibration process and corresponds to the type of the sample container, and obtaining the total liquid volume of the blood sample in the sample container according to the total liquid level and the conversion function, wherein the conversion function is a conversion relationship between the liquid level in the sample container and the volume of the blood sample; The step of obtaining the hematocrit of the blood sample in the sample container according to the total liquid level and the height of the lower layer liquid comprises: obtaining the conversion function corresponding to the type of the sample container according to the type of the sample container, and obtaining the hematocrit of the blood sample in the sample container according to the total liquid level, the height of the lower layer liquid and the conversion function; Alternatively, obtaining the total liquid volume of the blood sample in the sample container according to the total liquid level may include: obtaining a size parameter of the sample container according to an instruction input by an operator through a human-computer interaction device; obtaining the total liquid volume of the blood sample in the sample container according to the total liquid level and the size parameter; The step of obtaining the hematocrit of the blood sample in the sample container according to the total liquid level and the height of the lower layer liquid comprises: obtaining the hematocrit of the blood sample in the sample container according to the total liquid level, the height of the lower layer liquid and the size parameter.

17. The sample analysis system according to claim 12, wherein: There is a boundary liquid surface or boundary liquid layer between the intermediate layer liquid and the upper layer liquid; The first target image at least includes an image showing the interface liquid surface or the interface liquid layer in a two-dimensional form and / or a three-dimensional form; The second camera device is used for performing the second shooting action on the sample container along the horizontal direction before the first camera device performs the first shooting action on the sample container, in which the blood sample is loaded and after the blood sample is centrifuged and layered; The control device is further configured to: before acquiring the first target image, first control the second camera device to perform the second shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and layered, obtain the height position of the interface liquid surface or the interface liquid layer according to the image captured by the second camera device when performing the second shooting action, and obtain the target height position according to the height position of the interface liquid surface or the interface liquid layer; The obtaining of the first target image includes: controlling one of the sample container and the first camera device to move relative to the other and stop at the target height position, controlling the first camera device to perform the first shooting action on the sample container, and obtaining the first target image based on an image captured by the first camera device performing the first shooting action.

18. The sample analysis system according to any one of claims 1 to 9, characterized in that: The sample management device is provided with a loading area, a recovery area and a first abnormal area, wherein the loading area is used for placing the sample container to load the sample container, the recovery area is used for placing the sample container whose blood sample measurement result has been determined to be normal after being measured by the sample measuring device to recover the sample container, the first abnormal area is used for storing at least the sample container with abnormal code scanning, the sample container whose blood sample measurement result has been determined to be abnormal after being measured by the sample measuring device, and the sample container whose blood sample has abnormal clot phenomenon after being determined to be loaded by the first camera device, and the first storage space is located in the first abnormal area; Alternatively, the sample management device is provided with a loading area, a recovery area, a first abnormal area, and a second abnormal area, the loading area is used for placing the sample container to achieve loading of the sample container, the recovery area is used for placing the sample container whose blood sample measurement result has been determined to be normal after being measured by the sample measuring device to achieve recycling of the sample container, the first abnormal area is used for storing the sample container whose code scanning is abnormal and the sample container whose blood sample measurement result has been determined to be abnormal after being measured by the sample measuring device, the second abnormal area is used for storing the sample container whose blood sample has been determined to have abnormal clot phenomenon after being photographed by the first camera device, and the first storage space is located in the second abnormal area; Alternatively, the sample management device is provided with a loading area, a recovery area, a first abnormal area, a second abnormal area and a third abnormal area, the loading area is used for placing the sample container to realize the loading of the sample container, the recovery area is used for placing the sample container that has been determined by the sample measuring device to have a normal measurement result of the blood sample loaded therein to realize the recovery of the sample container, the first abnormal area is used for storing the sample container with abnormal code scanning, the second abnormal area is used for storing the sample container with abnormal clot phenomenon of the blood sample loaded therein determined by the first camera device taking an image, the third abnormal area is used for placing the sample container with abnormal blood sample measurement result of the blood sample loaded therein determined by the sample measuring device, and the first storage space is located in the second abnormal area; Alternatively, the sample management device is provided with a loading area, a recovery area and a first abnormal area, the loading area is used for placing the sample container to achieve loading of the sample container, the recovery area is used for placing the sample container that has been measured by the sample measuring device and the measurement result of the blood sample loaded therein is determined to be normal to achieve recovery of the sample container, the first abnormal area is used at least for storing the sample container with abnormal code scanning and the sample container that has been measured by the sample measuring device and the measurement result of the blood sample loaded therein is determined to be abnormal, the sample analysis system also includes a recovery container, the recovery container is located outside the sample management device, and the recovery container is located beside, below or above the sample container transmission device, the recovery container is used for placing the sample container that has been determined by the first camera device to have abnormal clot phenomenon in the blood sample loaded therein, and the first storage space is located in the recovery container.

19. The sample analysis system according to any one of claims 1 to 9, characterized in that: The sample container transmission device comprises a conveying track, a first sample container scheduling mechanism and a sample container transfer device, wherein the conveying track is used to convey a sample seat having a single first container position, wherein the first container position is used to place a single sample container; The first sample scheduling mechanism is used to schedule the sample container placed in the sample management device and loaded with the blood sample to the sample seat located on the conveying track; The sample container transfer device comprises a sample seat scheduling mechanism, a second sample container scheduling mechanism and a sample rack scheduling mechanism, wherein the sample seat scheduling mechanism is at least used to transport the sample seat transported by the transport track to the sample container transfer device to a rack position, and the second sample container scheduling mechanism is used to schedule the sample container on the sample seat at the rack position to a sample rack provided by the sample rack scheduling mechanism, wherein the sample rack has at least two second container positions, each of which is used to place a single sample container; the sample rack scheduling mechanism is used to schedule the sample rack loaded with the sample container and the blood sample in the sample container to the sample measurement device; Wherein, the first shooting position is located in the sample container transfer device, the first shooting position is set on the path of the sample container transfer device to transfer the sample container and is located between the conveying track and the sample measurement device, and the first camera device is used to perform the first shooting action on the sample container transferred from the sample container transfer device to the first shooting position; Alternatively, the first shooting position is located on the conveying track, the first shooting position is set on the path of the conveying track for conveying the sample container and is located between the first sample scheduling mechanism and the sample container transfer device, and the first camera device is used to perform the first shooting action on the sample container conveyed by the conveying track to the first shooting position; Alternatively, the first shooting position is located in the sample measuring device, the first shooting position is set on the path of the sample measuring device for conveying the sample container and is located before the sample suction position of the sample dispensing mechanism, and the first camera device is used to perform the first shooting action on the sample container conveyed by the sample measuring device to the first shooting position.

20. The sample analysis system according to any one of claims 1 to 9, characterized in that: The sample analysis system further comprises a centrifugal device, which is used to centrifuge the sample container loaded with the blood sample so as to centrifugally separate the blood sample into the upper layer of liquid, the middle layer of liquid, and the lower layer of liquid; The sample management device is used for placing the sample container loaded with the blood sample and not subjected to the centrifugation operation to realize the loading of the uncentrifuged blood sample, and for placing the sample container loaded with the blood sample and subjected to the centrifugation operation to realize the loading of the centrifuged blood sample; The sample container transfer device is at least used to transfer the sample container output from the sample management device and loaded with the uncentrifuged blood sample to the centrifuge device for centrifugation, to transfer the sample container output from the centrifuge device and loaded with the centrifuged blood sample to the sample measurement device, and to transfer the sample container output from the sample management device and loaded with the centrifuged blood sample to the sample measurement device; Wherein, the first photographing position is provided on the path where the sample container transporting device transports the sample container from the sample management device to the sample measuring device and is located between the centrifugal device and the sample measuring device, and the first camera device is used to perform the first photographing action on the sample container transported to the first photographing position by the sample container transporting device; Alternatively, the first shooting position is located in the sample measuring device, the first shooting position is set on the path of the sample measuring device for conveying the sample container and is located before the sample suction position of the sample dispensing mechanism, and the first camera device is used to perform the first shooting action on the sample container conveyed by the sample measuring device to the first shooting position.

21. A sample analysis system, characterized in that: include: A sample management device, the sample management device is at least used for placing a sample container loaded with a blood sample to achieve the loading of the blood sample; A sample measuring device, the sample measuring device comprising a sample dispensing mechanism and a measuring mechanism, the sample dispensing mechanism is used to absorb at least part of the upper layer liquid from the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer liquid, an intermediate layer liquid, and a lower layer liquid, and distribute it to a reaction container, the intermediate layer liquid containing platelets and / or leukocytes; the measuring mechanism is used to measure the test liquid in the reaction container made of at least the absorbed upper layer liquid and a reagent; a sample container transporting device, the sample container transporting device being used to transport the sample container loaded with the blood sample from the sample management device to the sample measuring device; a first camera device, the first camera device being used to perform a first photographing action on the sample container from obliquely above or obliquely below the middle layer liquid loaded in the sample container before the sample dispensing mechanism absorbs the upper layer liquid from the sample container; A control device, the control device being configured to: When a first sample container loaded with the blood sample and having abnormal clots in the blood sample is placed in the sample management device, the sample container transport device is controlled to transport the first sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to a first shooting position, the first camera device is controlled to perform the first shooting action on the first sample container located at the first shooting position, and the sample container transport device is controlled to transport the first sample container after the first shooting action is completed and the upper layer of liquid loaded therein is not measured by the measuring mechanism along the first route to the first storage space; When a second sample container loaded with the blood sample and having no abnormal clot phenomenon in the blood sample is placed in the sample management device, the sample container transmission device is controlled to transmit the second sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position, the first camera device is controlled to perform the first shooting action on the second sample container located at the first shooting position, the sample container transmission device is controlled to transmit the second sample container after the first shooting action is completed to the sample measurement device along a second route, the sample distribution mechanism is controlled to absorb at least part of the upper layer of liquid from the second sample container and distribute it to the first reaction container, and the measurement mechanism is controlled to measure the first test liquid made of at least the upper layer of liquid distributed to the first reaction container and a reagent; The first route is at least partially different from the second route.

22. The sample analysis system according to claim 21, characterized in that: When a first sample container loaded with the blood sample and having abnormal clotting phenomenon in the blood sample is placed in the sample management device, after controlling the first camera device to perform the first shooting action on the first sample container located at the first shooting position, the control device is further configured to: output prompt information for indicating that the blood sample in the first sample container has abnormal clotting phenomenon; Preferably, after the sample container transmission device is controlled to complete the first shooting action and transmits the first sample container along the first route to the first storage space without the upper liquid loaded therein being measured by the measuring mechanism, the control device is further configured to: output prompt information for characterizing the presence of abnormal clotting phenomenon in the blood sample in the first sample container.

23. The sample analysis system according to claim 21 or 22, characterized in that: The controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded by the measuring mechanism is not measured by the measuring mechanism along the first route to the first storage space comprises: according to the first target image obtained by the first camera device performing the first shooting action on the first sample container located at the first shooting position, controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded by the measuring mechanism is not measured by the measuring mechanism along the first route to the first storage space; Wherein, there is a boundary liquid surface or boundary liquid layer between the intermediate layer liquid and the upper layer liquid; The first target image at least includes an image showing the interface liquid surface or the interface liquid layer in a two-dimensional form and / or a three-dimensional form.

24. A sample analysis system, characterized in that: include: A sample management device, the sample management device is at least used for placing a sample container loaded with a blood sample to achieve the loading of the blood sample; A sample measuring device, the sample measuring device comprising a sample dispensing mechanism and a measuring mechanism, the sample dispensing mechanism is used to absorb at least part of the upper layer liquid from the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer liquid, an intermediate layer liquid, and a lower layer liquid, and distribute it to a reaction container, the intermediate layer liquid containing platelets and / or leukocytes; the measuring mechanism is used to measure the test liquid in the reaction container made of at least the absorbed upper layer liquid and a reagent; a sample container transporting device, the sample container transporting device being used to transport the sample container loaded with the blood sample from the sample management device to the sample measuring device; a first camera device, the first camera device being used to perform a first photographing action on the sample container from obliquely above or obliquely below the middle layer liquid loaded in the sample container before the sample dispensing mechanism absorbs the upper layer liquid from the sample container; A control device, the control device being configured to: When a first sample container loaded with the blood sample and having abnormal clotting phenomenon in the blood sample is placed in the sample management device, the sample container transmission device is controlled to transmit the first sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer liquid, a middle layer liquid, and a lower layer liquid to a first shooting position, the first camera device is controlled to perform the first shooting action on the first sample container located at the first shooting position, the sample container transmission device is controlled to transmit the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to a first storage space, and prompt information for indicating that the blood sample in the first sample container has abnormal clotting phenomenon is output; When a second sample container loaded with the blood sample and having no abnormal clot phenomenon in the blood sample is placed in the sample management device, the sample container transmission device is controlled to transmit the second sample container loaded with the blood sample and after the blood sample is centrifuged and stratified into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position, the first camera device is controlled to perform the first shooting action on the second sample container located at the first shooting position, the sample container transmission device is controlled to transmit the second sample container after completing the first shooting action to the sample measurement device, the sample distribution mechanism is controlled to absorb at least a part of the upper layer of liquid from the second sample container and distribute it to the first reaction container, and the measurement mechanism is controlled to measure a first test liquid made of at least the upper layer of liquid distributed to the first reaction container and a reagent.

25. The sample analysis system according to claim 24, characterized in that: The sample analysis system further includes a first display screen, the first display screen and the sample measuring device are independently arranged, the first display screen is used to display at least the storage information of the blood sample in the sample management device and the information of the blood sample transmitted by the sample container transmission device, and the outputting the prompt information indicating that the blood sample in the first sample container has a coagulation abnormality includes: controlling the first display screen to display the prompt information indicating that the blood sample in the first sample container has a coagulation abnormality; And / or, the sample measuring device further comprises a second display screen, the second display screen is used to display at least the measuring item information of the blood sample in the sample measuring device, and the outputting of the prompt information indicating that the blood sample in the first sample container has an abnormal clotting phenomenon comprises: controlling the second display screen to display the prompt information indicating that the blood sample in the first sample container has an abnormal clotting phenomenon; And / or, the outputting of the prompt information for indicating that the blood sample in the first sample container has an abnormal clotting phenomenon includes: transmitting the prompt information for indicating that the blood sample in the first sample container has an abnormal clotting phenomenon to a laboratory information management system that is communicatively connected to the sample analysis system; And / or, the sample analysis system also includes an alarm device, the alarm device includes a sound alarm component and / or a light alarm component, and the output is used to indicate that the blood sample in the first sample container has an abnormal clotting phenomenon, including: controlling the alarm device to emit a sound alarm signal and / or a light alarm signal for indicating that the blood sample in the first sample container has an abnormal clotting phenomenon.

26. The sample analysis system according to claim 24 or 25, characterized in that: The controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded thereon has not been measured by the measuring mechanism to the first storage space comprises: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded thereon has not been measured by the measuring mechanism to the first storage space according to a first target image obtained by the first camera device performing the first shooting action on the first sample container located at the first shooting position; Wherein, there is a boundary liquid surface or boundary liquid layer between the intermediate layer liquid and the upper layer liquid; The first target image at least includes an image showing the interface liquid surface or the interface liquid layer in a two-dimensional form and / or a three-dimensional form.

27. A control method for a sample analysis system, characterized in that: The control method comprises: Controlling the sample container transmission device to transmit the sample container loaded with the blood sample after the blood sample is centrifuged and separated into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position; Controlling the first camera device to perform a first shooting action on the sample container located at the first shooting position to obtain a first target image; determining, according to the first target image, whether the blood sample loaded in the sample container has abnormal clot phenomenon; If it is determined according to the first target image that the blood sample loaded in the sample container has an abnormal clot phenomenon, the sample container transmission device is controlled to transmit the sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism of the sample measuring device to the first storage space; If it is determined according to the first target image that the blood sample loaded in the sample container has no abnormal clot phenomenon, then the sample container transmission device is controlled to transmit the sample container after the first shooting action to the sample measurement device, the sample distribution mechanism of the sample measurement device is controlled to absorb at least part of the upper layer liquid from the sample container and distribute it to a first reaction container, and the measurement mechanism is controlled to measure a first test liquid made of at least the upper layer liquid distributed to the first reaction container and a reagent; Wherein, there is a boundary liquid surface or boundary liquid layer between the intermediate layer liquid and the upper layer liquid; The first target image at least includes an image showing the interface liquid surface or the interface liquid layer in a two-dimensional form and / or a three-dimensional form.

28. The control method of the sample analysis system according to claim 27, characterized in that: After determining that the blood sample loaded in the sample container has abnormal clotting phenomenon, the control method further includes: outputting prompt information for indicating that the blood sample in the sample container has abnormal clotting phenomenon; Preferably, after controlling the sample container transmission device to transmit the sample container to the first storage space after completing the first shooting action and without the upper layer liquid loaded therein being measured by the measuring mechanism of the sample measuring device, the control method further includes: outputting prompt information for characterizing the presence of abnormal clotting phenomenon in the blood sample in the sample container.

29. The control method of the sample analysis system according to claim 27 or 28, characterized in that: Before controlling the sample container transfer device to transfer the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into the upper layer liquid, the middle layer liquid, and the lower layer liquid to the first shooting position, the control method further includes: Controlling the sample container transfer device to transfer the sample container loaded with the blood sample after the blood sample is centrifuged and separated into the upper layer liquid, the middle layer liquid, and the lower layer liquid to the second shooting position; Controlling the second camera device to perform a second shooting action on the sample container located at the second shooting position to obtain a second target image; According to the second target image, at least one of the following information is obtained: the total liquid volume of the blood sample in the sample container, the hematocrit of the blood sample in the sample container, the hemolysis index of the blood sample in the sample container, the icterus index of the blood sample in the sample container, and the lipemia index of the blood sample in the sample container; When it is determined according to the second target image that the blood sample satisfies at least one of the following conditions: the total liquid volume of the blood sample is less than a first threshold, or the hematocrit of the blood sample is greater than a second threshold, or the hematocrit of the blood sample is less than a third threshold, or the hemolytic index of the blood sample is greater than a fourth threshold, or the icteric index of the blood sample is greater than a fifth threshold, or the lipemia index of the blood sample is greater than a sixth threshold, the sample container transport device is controlled to transport the sample container after the second shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism of the sample measuring device to the second storage space; The second storage space and the first storage space are the same storage space, or the second storage space and the first storage space are two different storage spaces.

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