Composition containing plant extract as well as preparation method and application thereof

Abstract

The invention relates to a composition containing plant extracts as well as a preparation method and application thereof. The invention provides a composition containing plant extracts, which is prepared from the following components in percentage by mass: 77.5 to 90 percent of water, 1 to 20 percent of willow herb extracting solution and 1 to 9 percent of 1, 2-hexanediol. The composition is simple in preparation method and high in stability, and has a relatively good effect of regulating the micro-ecology of the skin.

Description

Technical Field

[0001] The invention relates to a composition containing plant extracts, a preparation method and application thereof. Background Art

[0002] The skin is the largest organ in the human body and is our first line of defense against external damage. The earth is a large ecosystem, and the human body is actually a small micro-ecosystem. The human micro-ecosystem is divided into the oral cavity, skin, urinary tract, gastrointestinal tract, respiratory tract and skin. The skin microecology is also called the skin microecology, which is an ecosystem composed of various microorganisms such as bacteria, fungi, viruses, mites and arthropods, and tissues, cells and various secretions and microenvironments on the surface of the skin. Together, they maintain the balance of the skin microecology, forming the first biological barrier on the surface of the skin, and have important physiological functions.

[0003] Changes in skin microecology are related to the occurrence and development of skin problems such as excessive oil secretion, acne and skin inflammation. Skin microorganisms are an important component of the balance system. After a long process of biological evolution, normal flora and human body are in a symbiotic state and have established a close relationship with the human body. They have formed a unity of mutual dependence, mutual benefit, mutual coordination and mutual restraint with the body. This unity reflects the dynamic balance of human microecology. Balance means health, while imbalance causes disease.

[0004] An imbalance in the skin microbiome can lead to impaired skin health. For example, eczema flare-ups are caused by a loss of bacterial diversity in the skin, primarily due to an imbalance in Staphylococcus aureus bacteria. Normal skin does not lack microbial diversity. Common harmful skin bacteria can overgrow on the surface of the skin and cause skin problems. For example, Propionibacterium acnes is one of the common harmful skin bacteria. If Propionibacterium acnes overgrows on the skin, it can cause acne and pimples.

[0005] In recent years, plant extracts, essential oils, gums, resins, etc. have been proven to have in vitro and in vivo biological activity against pathogens such as bacteria, fungi and other microorganisms, and are widely accepted for their safety advantages compared to chemically synthesized products. Epilobium angustifolium is a perennial sturdy herb of the genus Epilobium of the family Onagraceae, also known as iron chopsticks and fire orchid. As an important Chinese herbal medicine, it has huge market development potential. According to the "Hubei Chinese Herbal Medicine Records", it has the effects of promoting blood circulation, removing blood stasis, setting bones, and relieving pain. It is mainly used to treat symptoms such as contusions, swelling, fractures, rheumatic pain, and dysmenorrhea.

[0006] At present, the imbalance of skin microbiota has also attracted some attention. Many countermeasures are to use drugs such as hormones and antibiotics, or treatment methods such as lasers and radio frequency, all of which have certain irritation or toxic side effects. Some drugs are prone to drug resistance after long-term use, which affects the skin and even the health of the body, thus causing concerns for people. Some corresponding products on the market are derived from plant extracts, but most of them are composites with complex ingredients that are difficult to distinguish. Therefore, the research on the role of angustifolia extract in maintaining the balance of skin microecology has good scientific research and market value. Summary of the invention

[0007] In order to regulate the changes in skin microecology and the occurrence of skin problems such as excessive oil secretion, acne and skin inflammation, the present invention provides a composition containing plant extracts, a preparation method thereof and an application thereof. The preparation method of the composition is simple, the stability is high, and it has a good effect of regulating skin microecology.

[0008] The present invention provides a composition containing plant extracts, which comprises (77.5-90)% water, (1-20)% angustifolia extract and (1-9)% 1,2-hexanediol, wherein the percentages are the mass percentages of the mass of each component to the total mass of the composition.

[0009] In the present invention, the composition containing plant extracts is preferably composed of 87.5% water, 10% angustifolia extract and 2.5% 1,2-hexanediol.

[0010] In the present invention, the preparation method of the angustifolia extract preferably comprises the following steps:

[0011] S1: In 1,2-hexanediol, angustifolia is subjected to ultrasonic extraction and then filtered to obtain filtrate A;

[0012] S2: at 40-60° C., the filtrate A is mixed with the viscose solution B; then mixed with the viscose solution A, allowed to stand, filtered, and the filtrate is centrifuged to obtain the supernatant to obtain the angustifolia extract;

[0013] The A viscose solution is composed of water and ZTCIII, and the B viscose solution is composed of water, acetic acid and ZTCIII.

[0014] In the present invention, the epilobium angustifolium is preferably produced in Xinjiang Uygur Autonomous Region, China. The epilobium angustifolium can be any part of the epilobium angustifolium plant or the whole epilobium angustifolium plant, including roots, stems, leaves and flowers. The epilobium angustifolium can be sliced ​​before ultrasonic extraction, preferably cut into slices of 1-2 cm in length.

[0015] In the present invention, the angustifolia is preferably washed before being sliced.

[0016] In the present invention, the water is preferably deionized water.

[0017] In one embodiment, in S1, the mass ratio of the angustifolia to the 1,2-hexanediol is 1:25.

[0018] In one embodiment, in S1, the power of the ultrasonic extraction equipment is 200-400W, for example, 300W.

[0019] In one embodiment, in S1, the frequency of the ultrasonic extraction is set to 30-50 kHz, for example, 40 kHz.

[0020] In one embodiment, in S1, the ultrasonic extraction is performed at room temperature, such as 25°C.

[0021] In a certain scheme, in S1, the time of the ultrasonic extraction is usually adjusted according to the conventional method in the art according to the quality of the angustifolia to be extracted, and can be 2-6 hours, for example, 4 hours.

[0022] In one embodiment, in S1, the pore size of the filter paper used for filtration is 0.3 μm-0.5 μm, for example, 0.45 μm.

[0023] In the present invention, in S2, the mass ratio of the viscose solution A to the viscose solution B is preferably 1:1.

[0024] In the present invention, in S2, the mass ratio of the filtrate A, the A viscose solution and the B viscose solution is 760:(12-5):(12-5); for example, 760:12:12.

[0025] In the present invention, in S2, the method for preparing the viscose solution A preferably comprises the following steps: mixing ZTCIII with water.

[0026] In the present invention, in S2, in the viscose solution A, the mass ratio of ZTCIII to water is preferably 1:(99-500), such as 1:99 or 1:399.

[0027] In the present invention, in S2, the method for preparing the B viscose solution preferably comprises the following steps: mixing ZTCIII with a 1% acetic acid aqueous solution.

[0028] In the present invention, in S2, in the B viscose solution, the mass ratio of the ZTCIII to the 1% acetic acid aqueous solution is preferably 1:(99-500), such as 1:99 or 1:399.

[0029] In the method for preparing the angustifolia extract, the step of allowing to stand is preferably performed at room temperature, usually 25°C.

[0030] In the preparation method of the angustifolia extract, the standing time is usually to perform preliminary solid sedimentation on the turbid liquid in preparation for filtration, and the preferred standing time is 5-12 hours, such as 6 hours.

[0031] In the method for preparing the angustifolia extract, the pore size of the filter paper used for filtration is preferably 0.3 μm-0.5 μm, such as 0.45 μm.

[0032] In the method for preparing the angustifolia extract, the centrifugal speed is preferably 3000-6000 rpm, such as 5000 rpm.

[0033] In the preparation method of the angustifolia extract, the centrifugation usually allows the solid to settle completely, preferably for 8-15 minutes, such as 10 minutes.

[0034] The present invention also provides a method for preparing the composition containing plant extracts, which comprises the following steps:

[0035] Just add 1,2-hexanediol and water to the angustifolia extract as described above;

[0036] In a certain embodiment, the mass ratio of the angustifolia extract, the 1,2-hexanediol and the water is 10:2.5:87.5.

[0037] The invention also provides a composition containing plant extracts prepared by the preparation method of the composition.

[0038] The invention also provides application of the composition containing the plant extract in cosmetics.

[0039] The cosmetics described in the present invention can be used by people with sensitive skin, especially those with skin inflammation, and can also be used as cosmetics for cleaning or caring for skin and / or hair, or as one of the ingredients added to makeup.

[0040] The cosmetics of the present invention are preferably cosmetics for external use, which generally refer to preparations for use outside the body rather than for internal administration.

[0041] The composition containing plant extracts in the present invention can be used in cosmetics after dilution. The dilution can be performed with distilled water. The target concentration of the dilution can be 0.001%-0.005%, for example, 0.0025%, where the mass percentage is the mass of the composition containing plant extracts to the total mass of the liquid after dilution. The target concentration of the dilution can also be 0.05%-0.25%, for example, 0.1%, where the mass percentage is the mass of the composition containing plant extracts to the total mass of the liquid after dilution.

[0042] The cosmetics described in the present invention can be skin protection cream, skin cleansing milk, skin cleansing soap, sunscreen lotion, nourishing cream, day cream, night cream, essence, eye cream, isolation cream, cleansing water, moisturizer, care solution, balancing muscle base lotion, deodorant, antiperspirant, shampoo, hair care agent, conditioner, shower gel, hand soap or hair dye, etc.

[0043] The composition containing plant extracts of the present invention can be used in cosmetics of various dosage forms, including: creams, emulsions, lotions, aqueous preparations, ointments, sprays, foams, soap bars, roller balls, gel beads, liquid soaps and gels, etc.

[0044] The present invention also provides application of the composition containing the plant extract in preparing oil-control cosmetics.

[0045] The present invention also provides application of the composition containing the plant extract in preparing cosmetics for inflammatory-sensitive skin.

[0046] In the present invention, the inflammatory-sensitive skin generally refers to skin that is prone to acne or has already developed acne.

[0047] In the present invention, the ZTCIII is a commercially available clarifier, for example, ZTCIII sold by Beijing Zhengtiancheng Clarification Technology Co., Ltd.

[0048] The positive and progressive effect of the present invention is that the composition containing the angustifolia plant extract of the present invention can be widely used in the field of cosmetics, has high stability, has good oil control, sterilization and acne inhibition effects, and has a significant regulating effect on skin microecology. BRIEF DESCRIPTION OF THE DRAWINGS

[0049] Figure 1 The finished product obtained in Example 1

[0050] Figure 2 The finished product obtained in Example 1 was stored for one month.

[0051] Figure 3 The finished product obtained in Example 1 was stored for two months.

[0052] Figure 4 The finished product obtained in Example 1 was stored for three months.

[0053] Figure 5 The finished product obtained in Comparative Example 1

[0054] Figure 6 The finished product obtained in Comparative Example 1 was stored for one month.

[0055] Figure 7 The finished product obtained in Comparative Example 1 was stored for two months.

[0056] Figure 8The finished product obtained in Comparative Example 1 was stored for three months. DETAILED DESCRIPTION

[0057] The present invention is further described below by way of examples, but the present invention is not limited to the scope of the examples. The experimental methods in the following examples without specifying specific conditions are carried out according to conventional methods and conditions, or selected according to the product specifications.

[0058] The components of the composition containing plant extracts prepared in the following examples are shown in the following table:

[0059] Table 1

[0060]

[0061] Fireweed Source

[0062] The fireweed used was sourced from Xinjiang Uyghur Autonomous Region, China.

[0063] Example 1

[0064] Wash the whole herb of Epilobium angustifolium, remove the soil and impurities to 30g, and cut into 1-2 cm long slices. Add 1,2-hexanediol at a ratio of 1:25 (solid: liquid) (the solid-liquid ratio is the mass ratio), put it into an ultrasonic extraction container, set the power of the ultrasonic equipment to 300W, the frequency to 40kHz, the temperature to room temperature (25℃), and extract for 4 hours. After the extraction, filter the extract with a pore size of 0.45μm filter paper to remove the residue. To obtain Epilobium angustifolium extract (filtrate A), heat 760g Epilobium angustifolium extract to 50℃, add 12g of B viscose solution, stir, and then add 12g of A viscose solution. Let it stand for 6 hours (room temperature), filter with a pore size of 0.45μm filter paper, take the filtrate, centrifuge at 5000rpm for 10min to take the supernatant, and obtain 750g Epilobium angustifolium extract.

[0065] 187.5 g of 1,2-hexanediol was added to the angustifolia extract, and the mixture was mixed evenly. Deionized water was then added thereto until the total mass of the solution was 7500 g, thereby obtaining a composition containing a plant extract.

[0066] Method of using the clarifier: ZTCIII clarifier is mixed with water to form a 1% clarifier viscose solution, wherein the mass ratio of the clarifier to water is 1:99, to obtain viscose solution A; ZTCIII clarifier is dissolved in 1% acetic acid, wherein the mass ratio of the clarifier to 1% acetic acid aqueous solution is 1:99, to obtain viscose solution B.

[0067] Example 2

[0068] Wash 30g of whole herb of Epilobium angustifolium, remove dirt and impurities, and cut into 1-2 cm long slices. Add 1,2-hexanediol at a ratio of 1:25 (solid: liquid) (the solid-liquid ratio is a mass ratio), put it into an ultrasonic extraction container, set the power of the ultrasonic equipment to 300W, the frequency to 40kHz, the temperature to room temperature (25°C), and extract for 4 hours. After the extraction, filter the extract with a 0.45μm filter paper to remove the residue. To obtain Epilobium angustifolium extract (filtrate A), heat 760g Epilobium angustifolium extract to 50°C, add 12g of B viscose solution, stir, and then add 12g of A viscose solution. Let it stand for 6 hours, filter with a 0.45μm filter paper, take the filtrate, centrifuge at 5000rpm for 10min, and take the supernatant to obtain 750g Epilobium angustifolium extract.

[0069] 187.5 g of 1,2-hexanediol was added to the angustifolia extract, and the mixture was mixed evenly. Deionized water was then added thereto until the total mass of the solution was 7500 g, thereby obtaining a composition containing a plant extract.

[0070] Method for using the clarifier: ZTCIII clarifier is mixed with water to form a 0.25% clarifier viscose solution, wherein the mass ratio of the clarifier to water is 0.25:99.75, to obtain viscose solution A; ZTCIII clarifier is dissolved in 1% acetic acid, wherein the mass ratio of the clarifier to the 1% acetic acid solution is 0.25:99.75, to obtain viscose solution B.

[0071] Example 3

[0072] 30g of whole herb of Epilobium angustifolium was cleaned, soil and impurities were removed, and sliced ​​into 1-2 cm long slices. 1,2-hexanediol was added in a ratio of 1:25 (solid: liquid) (the solid-liquid ratio is a mass ratio), and it was placed in an ultrasonic extraction container. The power of the ultrasonic equipment was set to 300W, the frequency was set to 40kHz, the temperature was set to room temperature (25°C), and the extraction was performed for 4 hours. After the extraction, the extract was filtered using a filter paper with a pore size of 0.45μm to remove the residue. The Epilobium angustifolium extract (filtrate A) was obtained. 760g of Epilobium angustifolium extract was heated to 50°C, 5g of B viscose solution was added, stirred, and then 5g of A viscose solution was added. Let it stand for 6 hours, filter it using a filter paper with a pore size of 0.45μm, take the filtrate, centrifuge it at 5000rpm for 10min, and take the supernatant to obtain 750g Epilobium angustifolium extract.

[0073] 187.5 g of 1,2-hexanediol was added to the angustifolia extract, and the mixture was mixed evenly. Deionized water was then added thereto until the total mass of the solution was 7500 g, thereby obtaining a composition containing a plant extract.

[0074] Method of using the clarifier: ZTCIII clarifier is mixed with water to form a 1% clarifier viscose solution, wherein the mass ratio of the clarifier to water is 1:99, to obtain viscose solution A; ZTCIII clarifier is dissolved in 1% acetic acid, wherein the mass ratio of the clarifier to 1% acetic acid solution is 1:99, to obtain viscose solution B.

[0075] Comparative Example 1

[0076] Wash 30g of whole herb of Epilobium angustifolium and remove dirt and impurities. Cut into 1-2 cm long slices. Add 1,2-hexanediol at a ratio of 1:25 (solid: liquid) (the solid-liquid ratio is a mass ratio), put it into an ultrasonic extraction container, set the ultrasonic equipment power to 300W, the frequency to 40kHz, the temperature to room temperature (25°C), and extract for 4 hours. After the extraction is completed, filter the extract with a filter paper with a pore size of 0.45μm to remove the residue, and obtain 750g of Epilobium angustifolium extract.

[0077] 187.5 g of 1,2-hexanediol was added to the angustifolia extract, and the mixture was mixed evenly. Deionized water was then added thereto until the total mass of the solution was 7500 g, thereby obtaining a composition containing a plant extract.

[0078] Stability test

[0079] The finished product obtained in Example 1 is as follows Figure 1 As shown (the four bottles from left to right are the finished products obtained in Example 1)

[0080] (Light yellow liquid, clear and transparent)

[0081] The finished product obtained in Example 1 was stored for 1 month. Figure 2 Shown

[0082] (Storage conditions of containers from left to right are -18℃, -7℃, 7℃, room temperature, sealed and kept away from light)

[0083] The finished product obtained in Example 1 was stored for 2 months. Figure 3 Shown

[0084] (Storage conditions of containers from left to right are -18℃, -7℃, 7℃, room temperature, sealed and kept away from light)

[0085] The finished product obtained in Example 1 was stored for 3 months. Figure 4 Shown

[0086] (Storage conditions of containers from left to right are -18℃, -7℃, 7℃, room temperature, sealed and kept away from light)

[0087] During the storage process, the smell, appearance and state of Example 1 did not change over time, and the stability was good.

[0088] The finished product obtained in Comparative Example 1 is as follows Figure 5 As shown (the four bottles from left to right are the finished products obtained from Comparative Example 1)

[0089] The results of Comparative Example 1 after 1 month of storage are as follows Figure 6 Shown

[0090] (Storage conditions of containers from left to right are -18℃, -7℃, 7℃, room temperature, sealed and kept away from light)

[0091] The results of comparative example 1 after 2 months of storage are as follows Figure 7 Shown

[0092] (Storage conditions of containers from left to right are -18℃, -7℃, 7℃, room temperature, sealed and kept away from light)

[0093] The results of comparative example 1 after 3 months of storage are as follows Figure 8 Shown

[0094] (Storage conditions of containers from left to right are -18℃, -7℃, 7℃, room temperature, sealed and kept away from light)

[0095] The color of Comparative Example 1 became lighter after being stored for a period of time, and its stability was poor.

[0096] Skin improvement: Oil control effect (FAS)

[0097] 1. Test principle

[0098] Fatty acid biosynthesis includes two enzyme systems: acetyl-CoA carboxylase (ACCase) and fatty acid synthase (FAS). ACCase catalyzes acetyl-CoA to generate malonyl-CoA, and FAS transfers the malonyl part to acyl carrier protein (ACP), using malonyl-ACP to catalyze the extension of the growing acyl chain. This experimental plan uses human sebaceous gland cells SZ95 (Shanghai Cell Bank, Chinese Academy of Sciences) to determine the effect of cosmetic raw materials on the expression of ACC and FAS genes related to lipid synthesis in cells, and explore the oil control effect of raw materials.

[0099] 2. Test methods are shown in Table 2

[0100] Table 2

[0101]

[0102] (2) Preparation of working fluid

[0103] ① Sample preparation: Dilute the samples to 0.005%, 0.0025%, and 0.001% as required, where % is the mass concentration, and dilute with distilled water.

[0104] ② Dilute linoleic acid and retinoic acid to corresponding concentrations respectively.

[0105] (The negative control (linoleic acid) is to simulate the increase in oil secretion, and the positive control (retinoic acid) is to verify the success of the model establishment)

[0106] (3) Operation steps

[0107] ① Cell plating: The cell concentration is 2×10 5 The cells were inoculated into a 6-well plate at a density of cells / mL, with 2 ml per well. The inoculated cell culture plate was placed in an incubator and cultured for 24 hours (5% CO2, 37°C).

[0108] ②Administration: After 24 h of cell culture, replace the blank culture medium, add the corresponding concentration of the test substance and linoleic acid to each well, mix well, and place in the incubator for 24 h + 1 h.

[0109] ③ RNA extraction: 24 hours later, RNA was extracted, cDNA was synthesized and PCR was performed (total RNA was isolated from the cell sphere using cell to RT-PCR reaction solution (For You Bio, China) and quantified using Qubit™ RNA BR Assay Kit (Invitrogen, USA). cDNA was synthesized in a 20 μL reaction containing 0.7 μg of total RNA, oligonucleotide (dT) and reverse transcription premix (Beyotime, China). 2 μL of cDNA product was PCR amplified using BeyoFast™ SYBR Green qPCR Mix (Beyotime, China).)

[0110] 3. Reagents and equipment see Table 3

[0111] Table 3

[0112]

[0113] Note: RT refers to room temperature, 25°C.

[0114] 4. Test results are shown in Table 4

[0115] Table 4

[0116] Summary table of FAS mRNA relative gene expression results

[0117]

[0118] Note: When using the t-test method for statistical analysis, the significance is indicated by * and P-value < 0.05 is indicated by * , P-value<0.01 is indicated as **, P-value<0.001 is indicated as *** ; Compared with the NC group, the significance is indicated by #, and P-value<0.05 is indicated by # , P-value<0.01 is indicated as ## , P-value<0.001 is indicated as ### Example 1-0.005% means that the composition containing plant extracts prepared in Example 1 is diluted with distilled water to obtain a sample to be tested with a mass concentration of 0.005%.

[0119] The calculation formula for PCR is 2^(-ΔΔCq)*100.

[0120] It can be seen from the above table that, under the same concentration, the PCR values ​​of Examples 1, 2, and 3 are significantly lower than those of Comparative Example 1, indicating that the oil control effect is better after adding the clarifier.

[0121] Skin improvement: Oil control effect (ACC)

[0122] 1. Test principle, equipment and method are the same as FAS

[0123] 2. Test results are shown in Table 5

[0124] Table 5

[0125] ACC mRNA relative gene expression results summary table

[0126]

[0127] Note: When the t-test method is used for statistical analysis, compared with the BC group, the significance is indicated by *, P-value <0.05 is indicated by *, P-value <0.01 is indicated by **, and P-value <0.001 is indicated by ***; compared with the NC group, the significance is indicated by #, P-value <0.05 is indicated by #, P-value <0.01 is indicated by ##, and P-value <0.001 is indicated by ###; Example 1-0.005% means that the composition containing the plant extract prepared in Example 1 is diluted with distilled water to obtain a sample to be tested with a mass concentration of 0.005%.

[0128] The calculation formula of PCR is 2^(-ΔΔCq)*100

[0129] It can be seen from the above table that, under the same concentration, the PCR values ​​of Examples 1, 2, and 3 are significantly lower than those of Comparative Example 1, indicating that the oil control effect is better after adding the clarifier.

[0130] Regulates skin microecology (inhibits Propionibacterium acnes)

[0131] 1. Test principle

[0132] Excessive proliferation of Propionibacterium acnes is one of the manifestations of skin microecological imbalance, which can also lead to the onset of acne and is considered to be a key factor in the pathogenesis of acne vulgaris. The interaction between Propionibacterium acnes and host skin cells is mainly mediated by Toll-like receptor (TLR-2) recognition.

[0133] 2. Test methods

[0134] Human normal sebocytes were inoculated in a 60 mm culture dish and cultured. The culture medium was replaced with serum-free medium. After LPS and the sample were treated together, the cells were cultured in a 37°C, 5% CO2 microbial incubator. After the culture medium was removed, the cells were collected using QIAzolTM lysis reagent and RNA was extracted according to the manufacturer's method. The extracted RNA was quantified and then synthesized into cDNA for real-time quantitative PCR (Applied Biosystems kit, fast real-time quantitative PCR instrument) to confirm the expression of the P. acnes receptor (TLR-2).

[0135] 3. Test results are shown in Table 6

[0136] Table 6

[0137]

[0138] In Table 6, "concentration %" means that the composition containing plant extracts prepared in the examples is diluted with distilled water to a liquid of corresponding mass concentration, wherein the mass concentration is the percentage of the mass of the composition containing plant extracts to the total mass of the diluted liquid.

[0139] It can be seen from the above table that, under the same concentration, Examples 1, 2, and 3 can effectively inhibit Propionibacterium acnes on the skin surface compared with Comparative Example 1.

Claims

1. A composition containing a plant extract, characterized in that It contains (77.5-90)% water, (1-20)% angustifolia extract and (1-9)% 1,2-hexanediol, wherein the % is the mass percentage of each component to the total mass of the composition.

2. The composition containing plant extracts according to claim 1, characterized in that It is composed of 87.5% water, 10% angustifolia extract and 2.5% 1,2-hexanediol.

3. The composition containing plant extracts according to claim 1, characterized in that The preparation method of the angustifolia extract comprises the following steps: S1: In 1,2-hexanediol, angustifolia is subjected to ultrasonic extraction and then filtered to obtain filtrate A; S2: at 40-60° C., mixing the filtrate A with the viscose solution B; then mixing it with the viscose solution A, letting it stand, and filtering; centrifuging the filtrate to obtain the supernatant to obtain the angustifolia extract; The A viscose solution is composed of water and ZTCIII, and the B viscose solution is composed of water, acetic acid and ZTCIII.

4. The composition containing plant extracts as claimed in claim 3, characterized in that The preparation method of the angustifolia extract satisfies one or more of the following conditions: (1) Slicing the angustifolia, preferably into slices 1-2 cm long; (2) preferably washing the Epilobium angustifolium before slicing the Epilobium angustifolium; (3) The water is deionized water; (4) In S1, the mass ratio of the angustifolia to the 1,2-hexanediol is 1:25; (5) In S1, the power of the ultrasonic extraction equipment is 200-400W, for example, 300W; (6) In S1, the frequency of the ultrasonic extraction is set to 30-50 kHz, for example, 40 kHz; (7) In S1, the ultrasonic extraction is performed at room temperature, for example, 25°C; (8) In S1, the ultrasonic extraction time is 2-6 hours, for example, 4 hours; (9) In S1, the pore size of the filter paper used for filtration is 0.3 μm-0.5 μm, for example, 0.45 μm; (10) In S2, the mass ratio of the A viscose solution to the B viscose solution is preferably 1:1; (11) In S2, the mass ratio of the filtrate A, the A viscose solution and the B viscose solution is 760:(12-5):(12-5); for example, 760:12:12; (12) In S2, the method for preparing the viscose solution A preferably comprises the following steps: mixing ZTCIII with water; (13) In S2, in the viscose solution A, the mass ratio of ZTCIII to water is preferably 1:(99-500), for example 1:99 or 1:399; (14) In S2, the method for preparing the B viscose solution preferably comprises the following steps: mixing ZTCIII with a 1% acetic acid aqueous solution; (15) In S2, in the B viscose solution, the mass ratio of ZTCIII to 1% acetic acid aqueous solution is preferably 1:(99-500), for example 1:99 or 1:399; (16) In S2, the standing is standing at room temperature, for example, 25°C; (17) In S2, the standing time is 5-12 hours, for example, 6 hours; (18) In S2, the pore size of the filter paper used for filtration is 0.3 μm-0.5 μm, for example, 0.45 μm; (19) In S2, the centrifugal speed is preferably 3000-6000 rpm, for example 5000 rpm; (20) In S2, the centrifugation time is 8-15 minutes, for example, 10 minutes.

5. A method for preparing a composition containing plant extracts as claimed in claim 1, characterized in that: It includes the following steps: (1) preparing an epilobium extract by the method for preparing an epilobium extract as claimed in claim 3; (2) Mixing the angustifolia extract prepared in step (1) with 1,2-hexanediol and water.

6. The preparation method according to claim 5, characterized in that: It meets one or more of the following conditions: (1) The mass ratio of the angustifolia extract, the 1,2-hexanediol and the water is 10:2.5:87.5; (2) The mixing means adding the 1,2-hexanediol first and then adding the water.

7. A composition containing plant extracts prepared by the preparation method according to claim 5 or 6.

8. Use of the composition containing plant extracts as claimed in claim 1 in cosmetics.

9. The use according to claim 8, characterized in that It meets one or more of the following conditions: (1) The composition containing the plant extract can be used in cosmetics after dilution; (2) The dilution mentioned above refers to dilution with distilled water; (3) The target concentration of the dilution is 0.001%-0.005%; for example: 0.0025%; the mass percentage is the percentage of the mass of the composition containing the plant extract to the total mass of the liquid after dilution; Alternatively, the target concentration of the dilution is also 0.05%-0.25%, for example: 0.1%, and the mass percentage is the percentage of the mass of the composition containing the plant extract to the total mass of the liquid after dilution.

10. The use according to claim 8, characterized in that The composition containing the plant extract is used in preparing oil-control cosmetics or cosmetics for inflammatory sensitive skin.

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