Composition with effects of controlling oil, removing acnes and minimizing pores, skin care product and preparation method thereof

Abstract

The invention discloses a composition with effects of controlling oil, removing acnes and minimizing pores, a skin care product and a preparation method of the composition. The composition comprises the following components in parts by mass: 0.5-8 parts of white willow bark extract, 0.1-1 part of Guangxi curcuma zedoary extract, 0.5-4.5 parts of medicinal phellinus igniarius extract and 0.005-0.05 part of lysozyme. The composition is prepared from the following components in parts by mass: 0.5-8 parts of white willow bark extract, 0.1-1 part of Guangxi curcuma zedoary extract, 0.5-4.5 parts of medicinal phellinus igniarius extract and 0.005-0.05 part of lysozyme. The skin care product comprises the composition. According to the composition with the effects of controlling oil, removing acnes and minimizing pores, the skin care product and the preparation method of the composition, the water-oil balance of the skin can be adjusted, the acnes are removed, the oil is controlled, the pores are minimized, and the skin barrier is maintained.

Description

Technical Field

[0001] The invention belongs to the technical field of cosmetics, and relates to a composition upgrading system, and in particular to a composition with the effects of controlling oil, removing acne and tightening pores, a skin care product and a preparation method thereof. Background Art

[0002] With the accelerated pace of life of modern people, increased work pressure, more entertainment options, etc., staying up late, irregular life, changing seasons and the influence of male hormones, the keratin metabolism rate is abnormal, and thick keratin accumulates around the pores, making the pores rough and easily blocked, resulting in an increase in the size of the hair follicles and thickening of the pores.

[0003] Nowadays, people pay more attention to skin care, and the pursuit of firm and delicate skin is getting stronger. Skin pores are often concerned because of their beauty problems. Skin pore problems are mainly manifested as oily, blocked and enlarged. There are many factors that affect the formation of enlarged pores. According to their different mechanisms, they can be summarized into endogenous factors including gender, age / skin aging, abnormal skin keratinization, vigorous sebum secretion, enlarged hair follicles, genetics, etc., as well as exogenous factors such as chronic ultraviolet exposure, exogenous irritants, improper skin care and bad living habits.

[0004] As the core component of oil-controlling, acne-removing, and pore-tightening cosmetics, the selection of active ingredients is crucial. However, due to the restrictions on formula application and my country's laws and regulations on related ingredients and dosage, commercially available oil-controlling, acne-removing, and pore-tightening skin care products generally have shortcomings such as single effective ingredients, slow effects, and unsatisfactory oil-controlling, acne-removing, and pore-tightening effects.

[0005] In view of this, there is an urgent need to design a new skin care product to overcome at least part of the above-mentioned defects of existing skin care products. Summary of the invention

[0006] The invention provides a composition with the effects of controlling oil, removing acne and tightening pores, a skin care product and a preparation method thereof, which can adjust the water-oil balance of the skin, remove acne, control oil and tighten pores, and maintain the skin barrier.

[0007] To solve the above technical problem, according to one aspect of the present invention, the following technical solution is adopted:

[0008] A composition with the effects of controlling oil, removing acne and tightening pores, comprising: 0.5-8 parts by weight of white willow bark extract, 0.1-1 parts by weight of Guangxi zedoaria extract, 0.5-4.5 parts by weight of medicinal pore fungus extract and 0.005-0.05 parts by weight of lysozyme.

[0009] As an embodiment of the present invention, the mass ratio of the white willow (SALIX ALBA) bark extract, the Guangxi Curcuma (CURCUMA KWANGSI ENSIS) extract, the medicinal pore fungus (FOMES OFFICINALIS) extract and lysozyme is (2-6): (0.3-0.8): (1-4): (0.01-0.05).

[0010] As an embodiment of the present invention, the white willow bark extract, Guangxi Curcuma zedoaria extract and lysozyme are dissolved in deionized water before use, wherein the mass ratio of the white willow bark extract to deionized water is (2-6):2, the mass ratio of the Guangxi Curcuma zedoaria extract to deionized water is (0.3-0.8):2, and the mass ratio of lysozyme to deionized water is (0.01-0.05):2.

[0011] According to another aspect of the present invention, the following technical solution is adopted: a skin care product, comprising the above-mentioned composition.

[0012] As an embodiment of the present invention, the skin care product is an essence, a cream, an emulsion or a skin care water.

[0013] As an embodiment of the present invention, the skin care product is an essence, and the essence comprises 5 to 25% by mass of the composition and 75 to 95% by mass of a cosmetic auxiliary material matrix.

[0014] As an embodiment of the present invention, based on the total mass of the raw materials for preparing the essence as 100%, the composition includes 2-6% by mass of Salix ALBA bark extract, 0.3-0.8% by mass of Curcuma KWANGSI ENSIS extract, 1-4% by mass of FOMES OFFICINALIS extract and 0.01-0.05% by mass of lysozyme;

[0015] The cosmetic auxiliary material matrix comprises: 0.2-35% by mass of a moisturizer, 0.2-1% by mass of a thickener, 0.5-1% by mass of a preservative, 0.1-5% by mass of a skin conditioner, 0.005-1% by mass of a daily essence; the balance is deionized water.

[0016] As an embodiment of the present invention, the cosmetic auxiliary material matrix includes a moisturizer, a thickener, a preservative, a skin conditioner, a daily fragrance and deionized water.

[0017] As an embodiment of the present invention, the moisturizing agent is selected from at least one of sodium hyaluronate, butylene glycol, hexylene glycol, pentylene glycol, glycerin, and dipropylene glycol;

[0018] The thickener is selected from at least one of carbomer, xanthan gum, acrylic acid (esters) / C10-30 alkyl acrylate cross-linked polymer, gellan gum, sodium acrylate / sodium acryloyldimethyl taurate, acrylic acid (esters) / C10-30 alkyl acrylate cross-linked polymer copolymer, hydroxyethyl cellulose, and agarose;

[0019] The preservative is selected from at least one of phenoxyethanol, ethylhexylglycerin, phenoxyethanol, sodium benzoate, pentylene glycol, and hexylene glycol; the skin conditioning agent is selected from at least one of allantoin, D-panthenol, and betaine.

[0020] According to another aspect of the present invention, the following technical solution is adopted: a method for preparing the above-mentioned skin care product, the preparation method comprising:

[0021] Step S1, completely dispersing the thickener in water to obtain a mixed solution;

[0022] Step S2, adding a moisturizer, a skin conditioner, and a preservative to the mixed solution, heating the mixture to a first temperature, and stirring the mixture to completely dissolve the mixture;

[0023] Step S3, cooling to a second temperature, adding the composition with oil-controlling, acne-removing, and pore-tightening effects and daily-use essence to the mixed solution obtained in step S2, stirring to completely dissolve them, and obtaining a skin care product with oil-controlling, acne-removing, and pore-tightening effects.

[0024] As an embodiment of the present invention, the first temperature is greater than or equal to 70°C and less than or equal to 90°C; the second temperature is greater than or equal to 30°C and less than or equal to 60°C.

[0025] As an embodiment of the present invention, the first temperature is 80°C; the second temperature is 45°C.

[0026] The beneficial effects of the present invention are as follows: the composition, skin care product and preparation method thereof with the effects of controlling oil, removing acne and tightening pores can adjust the water-oil balance of the skin, remove acne, control oil and tighten pores, and maintain the skin barrier.

[0027] The mechanism of enlarged pores is: a. abnormal skin keratinization; b. enlarged hair follicles; c. excessive secretion of sebaceous glands. The invention selects white willow (SALIX ALBA) bark extract, Guangxi Curcuma (CURCUMA KWANGSI ENSIS) extract, medicinal fennel (FOMES OFFICINALIS) extract and lysozyme as effective ingredients for oil control, acne removal and pore astringent effects, and the four ingredients act synergistically. The white willow (SALIX ALBA) bark extract is natural "salicylic acid" and aspirin in nature, and has similar effects to salicylic acid, and is very safe and mild; the medicinal fennel (FOMES OFFICINALIS) extract has a good inhibitory effect on the expression of inflammatory factors TNF-ɑ and IL-6, can well prevent and alleviate skin inflammation, and contains agaric acid, which is a natural astringent, has a good improvement effect on the volume of pores and hair follicles, can significantly increase the expression of COL-I, and can significantly inhibit the expression of MMP-1, so as to achieve the effect of astringing pores; the Guangxi Curcuma (CURCUMA KWANGSIENSIS) extract can inhibit the activity of type I and type II 5α-reductase to inhibit excessive secretion of sebaceous glands, achieving the effect of oil control and acne removal; the first domestic plant-derived recombinant human lysozyme, lysozyme can combine with peptidoglycan in the bacterial cell wall, causing the cell wall to lose its structure and function, thereby killing the bacteria, and can inhibit the growth of Propionibacterium acnes at a very low concentration, and can kill most of the bacteria, thereby achieving the effect of acne removal. The four active ingredients work together to inhibit the formation of acne and enlarged pores, thereby achieving the effect of oil control and acne removal and tightening pores.

[0028] The oil-controlling, acne-removing and pore-tightening effective ingredients of the present invention are matched according to specific proportions, and multiple effective ingredients are coordinated and synergistic with each other. The acid-free and acid-enzyme-free scrub regulates the water-oil balance of the skin, removes acne, tightens pores, maintains the skin barrier function, and solves enlarged pores and acne-prone skin from multiple aspects. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] Figure 1 The present invention is a flowchart of a method for preparing a skin care product in one embodiment of the present invention. DETAILED DESCRIPTION

[0030] The preferred embodiments of the present invention are described in detail below with reference to the accompanying drawings.

[0031] In order to further understand the present invention, preferred embodiments of the present invention are described below in conjunction with examples. However, it should be understood that these descriptions are only for further illustrating the features and advantages of the present invention, rather than limiting the claims of the present invention.

[0032] The description in this section is only for several typical embodiments, and the present invention is not limited to the scope of the embodiments. The same or similar prior art means and some technical features in the embodiments are mutually replaced within the scope of the present invention.

[0033] Unless otherwise indicated, implied from the context, or customary in the prior art, all parts and percentages in this application are based on weight, and the test and characterization methods used are all current as of the filing date of this application. Where applicable, the contents of any patent, patent application or publication referred to in this application are fully incorporated herein by reference, and their equivalent patent families are also incorporated by reference, especially the definitions of synthesis techniques, product and processing designs, polymers, comonomers, initiators or catalysts disclosed in these documents in the art. If the definition of a specific term disclosed in the prior art is inconsistent with any definition provided in this application, the definition of the term provided in this application shall prevail.

[0034] Numerical ranges in this application are approximate values, so unless otherwise specified, they may include numerical values ​​outside the range. Numerical ranges include all numerical values ​​from the lower limit to the upper limit increased by 1 unit, provided that there is an interval of at least 2 units between any lower value and any higher value. For example, if the recorded component, physical or other properties (such as molecular weight, melt index, etc.) are 100 to 1000, it means that all single values ​​are clearly listed, such as 100, 101, 102, etc., and all sub-ranges, such as 100 to 166, 155 to 170, 198 to 200, etc. For a range containing a numerical value less than 1 or containing a fraction greater than 1 (such as 1.1, 1.5, etc.), 1 unit is appropriately regarded as 0.0001, 0.001, 0.01 or 0.1. For a range containing a single digit less than 10 (such as 1 to 5), 1 unit is usually regarded as 0.1. These are only specific examples of what is intended to be expressed, and all possible combinations of values ​​between the lowest and highest values ​​listed are considered to be clearly recorded in this application. It should also be noted that the terms "first", "second", etc. in this article do not limit the order of precedence, but are only used to distinguish substances with different structures.

[0035] When used with respect to chemical compounds, unless expressly specified otherwise, the singular includes all isomeric forms and vice versa (e.g., "hexane" includes all isomers of hexane, individually or collectively). In addition, nouns using "a," "an," or "the" also include their plural forms unless expressly specified otherwise.

[0036] The terms "comprising", "including", "having" and their derivatives do not exclude the presence of any other components, steps or processes, and are irrelevant to whether these other components, steps or processes are disclosed in this application. To eliminate any doubt, unless explicitly stated, all compositions using the terms "comprising", "including", or "having" in this application may include any additional additives, adjuvants or compounds. On the contrary, except for those necessary for operating performance, the term "essentially consisting of..." excludes any other components, steps or processes from the scope of any description of the term below. The term "consisting of..." does not include any components, steps or processes that are not specifically described or listed. Unless explicitly stated, the term "or" refers to the listed individual members or any combination thereof.

[0037] The description of the steps in each embodiment in the specification is only for the convenience of explanation, and the implementation method of the present application is not limited by the order of implementation of the steps.

[0038] The invention discloses a composition with the effects of controlling oil, removing acne and tightening pores. The composition comprises: 0.5-8 parts by weight of white willow bark extract, 0.1-1 parts by weight of Guangxi zedoaria extract, 0.5-4.5 parts by weight of medicinal pore fungus extract and 0.005-0.05 parts by weight of lysozyme.

[0039] In one embodiment of the present invention, the mass ratio of the Salix Alba bark extract, the Curcuma Akwangsi Ensis extract, the Fomes Officinalis extract and lysozyme is (2-6): (0.3-0.8): (1-4): (0.01-0.05).

[0040] In one usage scenario of the present invention, the white willow (SALIX ALBA) bark extract, the Guangxi Curcuma (CURCUMAKWANGSI ENSIS) extract and the lysozyme are respectively dissolved in deionized water before use, wherein the mass ratio of the white willow bark extract to the deionized water is (2-6):2, the mass ratio of the Guangxi Curcuma extract to the deionized water is (0.3-0.8):2, and the mass ratio of the lysozyme to the deionized water is (0.01-0.05):2.

[0041] The present invention also discloses a skin care product, which comprises the above composition. The skin care product can be an essence, a cream, an emulsion or a skin care lotion.

[0042] In one embodiment of the present invention, the skin care product is an essence, which comprises 5-25% by weight of the composition and 75-95% by weight of a cosmetic auxiliary material matrix. The cosmetic auxiliary material matrix comprises a moisturizer, a thickener, a preservative, a skin conditioner, a daily fragrance and deionized water.

[0043] In one embodiment, based on the total mass of the raw materials for preparing the essence as 100%, the composition includes 0.5-8% by mass of Salix Alba bark extract, 0.1-1% by mass of Curcuma Kwangsi Ensis extract, 0.5-4.5% by mass of FOMES OFFICINALIS extract and 0.005-0.05% by mass of lysozyme. The composition may also include 2-6% by mass of Salix Alba bark extract, 0.3-0.8% by mass of Curcuma Kwangsi Ensis extract, 1-4% by mass of FOMES OFFICINALIS extract and 0.01-0.05% by mass of lysozyme. The cosmetic auxiliary material matrix comprises: 0.2-35% by mass of a moisturizer, 0.2-1% by mass of a thickener, 0.5-1% by mass of a preservative, 0.1-5% by mass of a skin conditioner, 0.005-1% by mass of a daily essence; the balance is deionized water.

[0044] In one embodiment of the present invention, the moisturizing agent is selected from at least one of sodium hyaluronate, butylene glycol, hexylene glycol, pentylene glycol, glycerin, and dipropylene glycol.

[0045] The thickener is selected from at least one of carbomer, xanthan gum, acrylates / C10-30 alkyl acrylate cross-linked polymer, gellan gum, sodium acrylate / sodium acryloyldimethyl taurate, acrylates / C10-30 alkyl acrylate cross-linked polymer copolymer, hydroxyethyl cellulose, and agarose.

[0046] The preservative is selected from at least one of phenoxyethanol, ethylhexylglycerin, phenoxyethanol, sodium benzoate, pentylene glycol, and hexylene glycol. The skin conditioning agent is selected from at least one of allantoin, D-panthenol, and betaine.

[0047] The present invention also discloses a method for preparing the above skin care product. Figure 1 is a flow chart of a method for preparing a skin care product in one embodiment of the present invention; the skin care product is an essence; please refer to Figure 1 , the preparation method comprises:

[0048] [Step S1] Completely dispersing the thickener in water to obtain a mixed solution;

[0049] [Step S2] Add moisturizer, skin conditioner, and preservative to the mixed solution, heat to a first temperature, and stir to completely dissolve them.

[0050] In an embodiment of the present invention, the first temperature is greater than or equal to 70° C. and less than or equal to 90° C., for example, the first temperature may be 80° C.

[0051] [Step S3] Cool down to the second temperature, add the composition with oil-controlling, acne-removing, and pore-tightening effects and the daily fragrance to the mixed solution formed in step S2, stir to make them completely dissolved, and obtain the skin care product with oil-controlling, acne-removing, and pore-tightening effects.

[0052] In an embodiment of the present invention, the second temperature is greater than or equal to 30° C. and less than or equal to 60° C., for example, the second temperature may be 45° C.

[0053] The invention discloses an essence composition with the effects of oil control, acne removal and pore tightening and a preparation method thereof. The main oil control, acne removal and pore tightening components of the essence composition include: white willow (SALIX ALBA) bark extract, Guangxi Curcuma (CURCUMA KWANGSI ENSIS) extract, medicinal pore fungus (FOMES OFFICINALIS) extract and lysozyme. By matching the components according to a specific ratio, multiple functional ingredients are mutually coordinated and synergistic, and acid-free acid-enzyme brushing is used to adjust the water-oil balance of the skin, remove acne, tighten pores, maintain the skin barrier function, and solve the problems of enlarged pores and acne-prone skin in multiple ways.

[0054] White willow (SALIX ALBA) bark extract helps oily skin and seborrheic skin by maintaining a balance in oil secretion. It is a natural "salicylic acid", aspirin in nature, with similar effects to salicylic acid, and is very safe and gentle. In the essence, it mainly plays the role of softening the epidermal keratin, softening and decomposing, gently removing keratin and refining pores.

[0055] Plant-derived recombinant human lysozyme can bind to the peptidoglycan in the bacterial cell wall, causing the cell wall to lose its structure and function, thereby killing the bacteria. It can inhibit the growth of Propionibacterium acnes at very low concentrations and can kill most of the bacteria, thereby achieving an acne-removing effect.

[0056] The extract of medicinal pore fungus (FOMES OFFICINALIS) has a good inhibitory effect on the expression of inflammatory factors TNF-ɑ and 1L-6, which can effectively prevent and relieve skin inflammation. It also contains agaric acid, which is a natural astringent. It has a good effect on improving the volume of pores and hair follicles, and can significantly increase the expression of COL-I. At the same time, it can significantly inhibit the expression of MMP-1, thereby achieving the effect of tightening pores.

[0057] Curcuma Kwangsi Ensis extract can inhibit the activity of type I and type II 5α-reductase to inhibit excessive secretion of sebaceous glands and achieve the effect of oil control and acne removal.

[0058] The present invention innovatively combines four oil-controlling, acne-removing and pore-tightening ingredients to remove acne, tighten pores, maintain skin barrier function, and solve enlarged pores and acne-prone skin from all aspects.

[0059] Examples 1-3

[0060] A cosmetic composition with the effects of controlling oil, removing acne and tightening pores is prepared into an essence, and the content of the raw material components is shown in the following Table 1.

[0061] Table 1 Raw material composition ratio table of Examples 1-3 (unit: mass %)

[0062]

[0063]

[0064] The preparation process of the essence with the effects of oil control, acne removal and pore tightening in Examples 1-3 comprises the following steps:

[0065] 1) The thickener in phase A is completely wetted and dispersed in water to obtain a mixed solution;

[0066] 2) Add other moisturizers, skin conditioners and preservatives in phase A to the mixed solution in step 1), heat to 80° C., stir to completely dissolve, and cool to 45° C.;

[0067] 3) The raw materials of phase B, phase C and phase D are mixed respectively, and then added to the mixture obtained in step 2), and stirred to completely dissolve, thereby obtaining an essence with the effects of oil control, acne removal and pore tightening.

[0068] The preparation process of blank example essence is as follows:

[0069] 1) The thickener in phase A is completely wetted and dispersed in water to obtain a mixed solution;

[0070] 2) Add other moisturizers, skin conditioners and preservatives in phase A to the mixed solution in step 1), heat to 80° C., stir to completely dissolve; cool to 45° C.;

[0071] 3) The raw materials of phase B and phase D are mixed separately, and then added to the mixture obtained in step 2), and stirred to completely dissolve, thereby obtaining an essence with the effects of oil control, acne removal and pore tightening.

[0072] Comparative Examples 1-8

[0073] According to the raw material composition ratio in Table 2-3, the essence is prepared:

[0074] Table 2 Composition ratio of the oil-controlling, acne-removing and pore-tightening essence of comparative examples 1-4 (unit: mass %)

[0075]

[0076]

[0077] Table 3 Composition ratio of the oil-controlling, acne-removing and pore-tightening essence of comparative examples 5-8 (unit: mass %)

[0078]

[0079]

[0080] The preparation process of the essence of the above-mentioned reference examples 1-8 comprises the following steps:

[0081] 1) The thickener in phase A is completely wetted and dispersed in water to obtain a mixed solution;

[0082] 2) Add other moisturizers, skin conditioners and preservatives in phase A to the mixed solution in step 1), heat to 80° C., stir to completely dissolve, and cool to 45° C.;

[0083] 3) The raw materials of phase B, phase C and phase D are mixed respectively, and then added to the mixture obtained in step 2), and stirred to completely dissolve, thereby obtaining an essence with the effects of oil control, acne removal and pore tightening.

[0084] Effect verification test example

[0085] 1. Security Testing

[0086] Test samples: Examples 1-3, Comparative Examples 1-8 and Blank Examples;

[0087] Test subjects: 120 subjects aged 20-35 were selected and randomly divided into 12 groups, with 10 people in each group.

[0088] Test method: Use a third-party testing agency to test safety. Select an area not exceeding 50mm 2 , a suitable patch with a depth of about 1mm, and using the closed patch test method, add about 0.02-0.025ml (g) of the test sample (the essence prepared in Examples 1-3, Control Examples 1-8 and Blank Example, respectively) into the patch tester. The patch tester was attached to the curved side of the forearm of the subjects (120 people), and the test substance was removed after 24 hours. The skin reaction was observed at 0.5h, 24h, and 48h after removal, and the results were recorded according to the skin reaction grading standards in the "Cosmetic Safety Technical Regulations 2015".

[0089] Notes: Skin reaction grading standards;

[0090] Grade 0: negative reaction;

[0091] Grade 1: Suspicious reaction; only slight erythema;

[0092] Grade 2: weak positive reaction (erythema reaction); erythema, infiltration, edema, and papules may be present;

[0093] Grade 3: Strong positive reaction (herpes reaction); erythema, infiltration, edema, papules, herpes; the reaction may extend beyond the test area;

[0094] Grade 4: Very strong reaction (confluent herpes reaction); obvious erythema, severe infiltration, edema, confluent herpes, and the reaction exceeds the test area.

[0095] Table 4 Patch test results

[0096]

[0097]

[0098] The results in Table 4 show that the scores of the essences prepared in the embodiments, control examples and blank examples were all 0 at 0.5 h, 24 h and 48 h, and no adverse skin reactions occurred, indicating that the composition and essence products of the present invention are safe and non-irritating to the skin.

[0099] 2. Stability test

[0100] Test samples: Examples 1-3;

[0101] Test method: Internal control standard: observe the appearance color and pH for three months.

[0102] Table 5 Comparison table of stability investigation results

[0103]

[0104] In Table 5, W represents week, M represents month, and cycle represents that the temperature cycles from 50°C to -15°C once a day.

[0105] The color, viscosity and pH of the essence prepared in the example did not change significantly under high or low temperature or light exposure within three months, which shows that the essence of the present invention has good stability.

[0106] 3. Oil control efficacy test experiment

[0107] Skin oil content test:

[0108] Test instrument: Sebumeter SM815, produced by CK Company of Germany.

[0109] Test conditions: constant temperature and humidity environment, temperature 23±1℃, humidity 50%±5%. Before the test, the subjects should sit quietly in this environment for at least 30 minutes.

[0110] A total of 120 subjects with oily skin were recruited, including 60 males and 60 females, and randomly divided into 12 groups, with 10 subjects in each group.

[0111] The oil content of the skin on both sides of the nose of the subjects was tested using the oil tester Sebumeter SM815 (μg / cm 2 ), recorded as T0 (average value of 10 people in each group). After washing the face, each subject applied the essence obtained from Examples 1, 2, 3, the control example and the blank example on the face, especially on both sides of the nose, once in the morning and evening every day, for 4 weeks. The skin oil content on both sides of the nose of the subject was tested with an oil tester every week, and the oil content values ​​of T1 (1 week), T2 (after 2 weeks), T3 (after 3 weeks) and T4 (after 4 weeks) were recorded respectively, and the average value of 10 people in each group was calculated, and the oil content change rate was further calculated. The results are shown in Table 6.

[0112] The rate of change of fat content = (the average fat content of 10 people in each group after using the test sample - the average fat content of 10 people in each group before using the test sample, i.e., at T0) / the average fat content of 10 people in each group before using the test sample, i.e., at T0.

[0113] The results are shown in Table 6 below.

[0114] Table 6 Test results comparison table

[0115]

[0116] As can be seen from Table 6, the essence liquid composition with oil control, acne removal and pore tightening effects obtained in Examples 1-3 of the present invention can effectively inhibit oil secretion, while when one or two of the functional components of the present application are added to the essence liquid obtained in the control example, there is a certain effect of inhibiting oil secretion, but the effect is far less than that of Examples 1-3, proving that the combination of the functional components of the present application produces a synergistic effect, while the essence liquid composition obtained in the blank example has almost no effect of inhibiting oil secretion. It shows that the essence liquid with oil control, acne removal and pore tightening effects of the present invention has an oil control effect.

[0117] 4. Facial image acquisition and acne analysis test

[0118] The effects of Example 1 and Control Examples 1-8 of the synergistic enhancement experiment of oil control, acne removal and pore tightening components were verified, and the experimental steps and results are as follows:

[0119] 1) Test subjects: 90 healthy women (20-45 years old), divided into 9 groups, each with 10 people; each group used the same formula product.

[0120] 2) Test area: the entire face.

[0121] 3) Usage: Use twice a day, morning and evening. Apply an appropriate amount of the test sample to the entire face, and apply sunscreen products to the entire face every morning.

[0122] The results were tested at the following four time periods: before using the sample (D0), 14 days after using the sample (D14), 28 days after using the sample (D28), and 56 days after using the sample (D56). The average value of 10 people in each group was calculated.

[0123] 4) Test instrument: German CK model: PRIMOS pico rapid three-dimensional skin imaging system.

[0124] 5) Effect indicators: Primos is used for facial image acquisition and acne analysis.

[0125] 6) Change in skin acne volume (%) = (average skin acne volume of 10 people in each group after using the test sample - average skin acne volume of 10 people in each group before using the test sample, i.e., at D0) / average skin acne volume of 10 people in each group before using the test sample, i.e., at D0.

[0126] The results of skin acne volume change are shown in Table 7.

[0127] Table 7 Test group effect comparison table

[0128]

[0129]

[0130] From the results of Table 7, it can be seen that when the extract of Salix Alba bark, Curcuma Kwangsi Ensis, Fomes Officinalis and lysozyme are added to the essence at the same time, the ability to reduce acne is 21.66%, 32.37% and 42.85% on the 14th, 28th and 56th days respectively, and its anti-acne ability is significantly greater than that of the control examples 1-8, which shows that the anti-acne ability of the four components used at the same time is significantly improved compared with some components and a single component, and it can be concluded that the four components have a synergistic function in acne removal. The emergence of this synergistic function is due to the different division of labor and cooperation of the four components used in acne removal and anti-inflammation, removing acne from all aspects, converging pores, maintaining skin barrier function, and solving enlarged pores and acne skin in all directions.

[0131] 5. Evaluation of pore improvement effect

[0132] The effects of Example 1 and Control Examples 1-8 of the synergistic enhancement experiment of oil control, acne removal and pore tightening components were verified, and the experimental steps and results are as follows:

[0133] 1) Test subjects: 90 healthy women (20-45 years old), divided into 9 groups, each with 10 people; each group used the same formula product.

[0134] 2) Test area: the entire face.

[0135] 3) Usage: Use twice a day, morning and evening. The method of use and dosage should be consistent. The experimenter will take VISIA photos and Primos CR pictures on D0, D14 and D28 respectively.

[0136] 4) Test equipment: VISIA and Primos CR

[0137] Effect verification (1): VISIA was used to collect facial image information and analyze photos. Feature counting means counting feature parameters without calculating the size and strength of feature parameters. A smaller value indicates better skin. Score means evaluating the size, area, and strength of feature parameters. A smaller score indicates better skin. SPSS28.0 was used for statistical analysis of data. If the test data was normally distributed, the T test method was used for statistical analysis. If the test data was non-normally distributed, the rank sum test method was used for statistical analysis. The rank sum test was used for statistical analysis of graded data. The statistical method significance level p < 0.05; the statistical results are shown in Table 8.

[0138] Table 8 Statistical data

[0139]

[0140]

[0141] From the data in Table 8, it can be seen that compared with before using the sample, after using the essence of Example 1 for 14 days, the characteristic count of skin pores on the cheek decreased by 4.28%, the skin pore score decreased by 8.45%, and the skin pore percentile decreased by 3.24%; after using the essence of Example 1 for 28 days, the characteristic count of skin pores on the cheek decreased by 5.83%, the skin pore score decreased by 20.31%, and the skin pore percentile decreased by 11.48% without significant difference. The effect is significantly better than that of the control example, indicating that the simultaneous addition of Salixalba bark extract, Curcuma Kwangsi Ensis extract, Fomes Officinalis extract and lysozyme has a synergistic promotion effect on the effect of finely astringing pores that is difficult for those skilled in the art to predict, and more effectively smooths the skin and shrinks pores.

[0142] Effect verification (2): VISIA was used to collect facial images and combined with Image-pro skin comprehensive analysis software for photo analysis. The skin pore analysis value became smaller, indicating that the skin pores have improved. The statistical results are shown in Table 9 (average decrease rate of 10 people in each group).

[0143] Table 9 Statistical data

[0144]

[0145]

[0146] It can be seen from the data in Table 9 that the essence with the effects of controlling oil, removing acne and tightening pores of the present invention has excellent effect of refining pores, and it can be seen from the data of Example 1 and Control Examples 1-8 that the four ingredients of SALIX ALBA bark extract, CURCUMA KWANGSI ENSIS extract, FOMES OFFICINALIS extract and lysozyme have a synergistic promoting effect in improving the effect of pores.

[0147] Effect verification (3): A subject of Example 1 was randomly selected, such as Figure 1 The figure shows the intuitive effect diagram of the local pore area ratio after using the sample of Example 1 of the present invention. The blue dots represent the number of pores. The left one is the intuitive effect diagram of the local pore area ratio on the 0th day, and the right one is the intuitive effect diagram of the local pore area ratio on the 28th day. Figure 1 It can be seen intuitively that after using the sample of Example 1 of the present invention for 28 days, the pores are obviously reduced visibly.

[0148] In summary, the composition, skin care product and preparation method thereof with the effects of controlling oil, removing acne and tightening pores proposed in the present invention can adjust the water-oil balance of the skin, remove acne, control oil and tighten pores, and maintain the skin barrier.

[0149] The mechanism of enlarged pores is: a. abnormal skin keratinization; b. enlarged hair follicles; c. excessive secretion of sebaceous glands. The invention selects white willow (SALIX ALBA) bark extract, Guangxi Curcuma (CURCUMA KWANGSI ENSIS) extract, medicinal fennel (FOMES OFFICINALIS) extract and lysozyme as effective ingredients for oil control, acne removal and pore astringent effects, and the four ingredients act synergistically. The white willow (SALIX ALBA) bark extract is natural "salicylic acid" and aspirin in nature, and has similar effects to salicylic acid, and is very safe and mild; the medicinal fennel (FOMES OFFICINALIS) extract has a good inhibitory effect on the expression of inflammatory factors TNF-ɑ and IL-6, can well prevent and alleviate skin inflammation, and contains agaric acid, which is a natural astringent, has a good improvement effect on the volume of pores and hair follicles, can significantly increase the expression of COL-I, and can significantly inhibit the expression of MMP-1, so as to achieve the effect of astringing pores; the Guangxi Curcuma (CURCUMA KWANGSIENSIS) extract can inhibit the activity of type I and type II 5α-reductase to inhibit excessive secretion of sebaceous glands, achieving the effect of oil control and acne removal; the first domestic plant-derived recombinant human lysozyme, lysozyme can combine with peptidoglycan in the bacterial cell wall, causing the cell wall to lose its structure and function, thereby killing the bacteria, and can inhibit the growth of Propionibacterium acnes at a very low concentration, and can kill most of the bacteria, thereby achieving the effect of acne removal. The four active ingredients work together to inhibit the formation of acne and enlarged pores, thereby achieving the effect of oil control and acne removal and tightening pores.

[0150] The oil-controlling, acne-removing and pore-tightening effective ingredients of the present invention are matched according to specific proportions, and multiple effective ingredients are coordinated and synergistic with each other. The acid-free and acid-enzyme-free scrub regulates the water-oil balance of the skin, removes acne, tightens pores, maintains the skin barrier function, and solves enlarged pores and acne-prone skin from multiple aspects.

[0151] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0152] The description and application of the present invention here are illustrative, and it is not intended to limit the scope of the present invention to the above-mentioned embodiments. The effects or advantages involved in the embodiments may not be embodied in the embodiments due to interference from various factors, and the description of the effects or advantages is not used to limit the embodiments. The deformation and change of the embodiments disclosed here are possible, and the replacement of the embodiments and the various equivalent parts are well known to those of ordinary skill in the art. It should be clear to those skilled in the art that the present invention can be implemented in other forms, structures, arrangements, proportions, and with other components, materials and parts without departing from the spirit or essential features of the present invention. Other deformations and changes can be made to the embodiments disclosed here without departing from the scope and spirit of the present invention.

Claims

1. A composition having the effects of controlling oil, removing acne and tightening pores, characterized in that: The composition comprises: 0.5-8 parts by weight of white willow bark extract, 0.1-1 parts by weight of Guangxi zedoaria extract, 0.5-4.5 parts by weight of medicinal pore fungus extract and 0.005-0.05 parts by weight of lysozyme.

2. The skin care product according to claim 1, characterized in that: The mass ratio of the willow bark extract, the zedoaria zedoaria extract, the medicinal pore fungus extract and the lysozyme is (2-6): (0.3-0.8): (1-4): (0.01-0.05).

3. The skin care product according to claim 2, characterized in that: The white willow bark extract, Guangxi Curcuma zedoaria extract and lysozyme are respectively dissolved in deionized water before use, wherein the mass ratio of the white willow bark extract to deionized water is (2-6):2, the mass ratio of the Guangxi Curcuma zedoaria extract to deionized water is (0.3-0.8):2, and the mass ratio of lysozyme to deionized water is (0.01-0.05):

2.

4. A skin care product, characterized in that: The skin care product comprises the composition according to any one of claims 1 to 3.

5. The skin care product according to claim 4, characterized in that: The skin care product is essence, cream, lotion or skin care water.

6. The skin care product according to claim 4, characterized in that: The skin care product is an essence, which comprises 5-25% by mass of the composition and 75-95% by mass of a cosmetic auxiliary material matrix.

7. The skin care product according to claim 6, characterized in that: Taking the total mass of the raw materials for preparing the essence as 100%, the composition comprises 2-6% by mass of a willow bark extract, 0.3-0.8% by mass of a zedoaria zedoaria extract, 1-4% by mass of a medicinal pore fungus extract, and 0.01-0.05% by mass of lysozyme; The cosmetic auxiliary material matrix comprises: 0.2-35% by mass of a moisturizer, 0.2-1% by mass of a thickener, 0.5-1% by mass of a preservative, 0.1-5% by mass of a skin conditioner, 0.005-1% by mass of a daily essence; the balance is deionized water.

8. The skin care product according to claim 6, characterized in that: The cosmetic auxiliary material matrix includes a moisturizer, a thickener, a preservative, a skin conditioner, a daily fragrance and deionized water; The moisturizing agent is selected from at least one of sodium hyaluronate, butylene glycol, hexylene glycol, pentylene glycol, glycerin, and dipropylene glycol; The thickener is selected from at least one of carbomer, xanthan gum, acrylic acid (esters) / C10-30 alkyl acrylate cross-linked polymer, gellan gum, sodium acrylate / sodium acryloyldimethyl taurate, acrylic acid (esters) / C10-30 alkyl acrylate cross-linked polymer copolymer, hydroxyethyl cellulose, and agarose; The preservative is selected from at least one of phenoxyethanol, ethylhexylglycerin, phenoxyethanol, sodium benzoate, pentylene glycol, and hexylene glycol; The skin conditioning agent is selected from at least one of allantoin, D-panthenol and betaine.

9. A method for preparing the skin care product according to any one of claims 4 to 8, characterized in that: The skin care product is an essence; the preparation method comprises: Step S1, completely dispersing the thickener in water to obtain a mixed solution; Step S2, adding a moisturizer, a skin conditioner, and a preservative to the mixed solution, heating the mixture to a first temperature, and stirring the mixture to completely dissolve the mixture; Step S3, cooling to a second temperature, adding the composition with oil-controlling, acne-removing, and pore-tightening effects and daily-use essence to the mixed solution obtained in step S2, stirring to completely dissolve them, and obtaining a skin care product with oil-controlling, acne-removing, and pore-tightening effects.

10. The preparation method according to claim 9, characterized in that: The first temperature is greater than or equal to 70° C. and less than or equal to 90° C.; the second temperature is greater than or equal to 30° C. and less than or equal to 60° C.

Images