Chinese herbal medicine eyesight-improving health-care patch containing nitric oxide precursor and preparation process of Chinese herbal medicine eyesight-improving health-care patch
By using materials such as nitric oxide precursors, far-infrared ceramic powder and magnetic powder in the eye-opening health patch, the existing eye-opening health patch has been solved, and more efficient eye fatigue treatment and vision rehabilitation effects have been achieved.
Patent Information
- Application Number
- CN202410475340.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-19
- Publication Date
- 2025-05-06
AI Technical Summary
The existing eye-enhancing health patches have poor results in treating and relieving eye fatigue and cannot effectively improve the effect of vision rehabilitation.
The Chinese herbal medicine eye-catching health patch containing nitric oxide precursor is used to regulate the opening and closing of skin pores through the heating effect of far-infrared ceramic powder, the stimulation of the eye acupoints by magnetic powder, and the coordinated combination of various raw materials is significantly improved, which is the infiltration efficiency and utilization rate of medicinal ingredients.
It significantly improves the treatment and relief effect of eye fatigue, enhances the effect of nitrogen monoxide on the eyes, and is suitable for large-scale promotion and application.
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of medical and health care products, and in particular to a Chinese herbal medicine eye-improving health care patch containing a nitric oxide precursor and a preparation process thereof. Background Art
[0002] With the development of the information age, computers and mobile phones have become essential tools for everyone. People spend more than eight hours a day looking at their phones or computers. Therefore, the damage and overuse of computers and mobile phones to the eyes are self-evident. Eye fatigue has become the most common eye health problem today. Eye fatigue is also called visual fatigue. The main symptoms are dry eyes, astringent eyes, sore eyes, blurred vision and even decreased vision. Severe visual fatigue patients will also have varying degrees of systemic symptoms, such as headaches, dizziness, weakness, nausea and vomiting, which directly affect people's work and life. Therefore, relieving and treating eye fatigue is something that everyone should pay attention to. In order to relieve eye fatigue, in addition to natural rest and massage creams, various eye health products are also common ways. Among them, eye patches are one of the most widely used health care products for relieving and treating eye fatigue. They have many advantages such as easy use, low cost, multiple indications, and good effects.
[0003] At the same time, the latest research has found that vascular endothelial cells of the choroid and retina, outer segments of rod cells, retinal neurons, choroidal vascular nerve fibers, retinal pigment epithelial cells, etc., can all produce nitric oxide, and it is widely distributed in the tertiary neurons of the visual system. Further research has found that nitric oxide is not only a newly discovered neurotransmitter, but can also participate in visual development, integration and transmission of visual information with some neurotransmitters and neuropeptides, and participate in synaptic plasticity of the visual nervous system; moreover, nitric oxide can also dilate blood vessels, increase blood flow, and regulate the blood circulation of the central nervous system and the arteries and retinal capillaries inside and outside the eyeball, thereby improving symptoms such as eye fatigue and impaired vision caused by long-term use of the eyes by regulating blood circulation.
[0004] Therefore, the eye care patch is combined with a substance that can produce nitric oxide for relieving and treating eye fatigue, which has a positive effect on improving the relief and therapeutic effect of the eye care patch on eye fatigue. For example, patent CN107029037A is a kind of eye care patch based on the nitric oxide principle to improve the eyes, which is exactly according to the theory of traditional Chinese medicine and drug transdermal absorption technology, selects the drug formula, combines the traditional and modern technology to refine the eye care patch, can stimulate the eye peripheral nerve receptors and peripheral blood vessels, effectively improve the blood circulation around the eye and the internal nerve regulation, improve the blood circulation and metabolism of the eye tissue, restore the physiological regulation of the eye muscle, so as to achieve the purpose of effectively improving vision rehabilitation. However, the above-mentioned eye care patch is due to the problem of raw material selection and only adopting the traditional osmotic drug administration method, resulting in the poor effect of the health care patch, and the relief and therapeutic effect of the eye cannot reach the expected. Summary of the invention
[0005] The purpose of the present invention is to overcome the shortcomings of the existing eyesight health care patch in that the treatment and relief effects on eye fatigue are poor, and to provide a Chinese herbal medicine eyesight health care patch containing a nitric oxide precursor and a preparation process thereof.
[0006] In order to achieve the above-mentioned purpose of the invention, the present invention provides a Chinese herbal medicine eye-improving health care patch containing a nitric oxide precursor, which is prepared by the following raw materials in parts by weight: 3-6 parts of a nitric oxide precursor, 10-15 parts of a magnetic powder, 15-25 parts of a porous far-infrared ceramic powder, 0.5-2 parts of taurine, 0.2-0.5 parts of musk, 0.1-0.3 parts of menthol, 1-3 parts of frankincense, 0.1-0.5 parts of wild chrysanthemum extract, 0.1-0.2 parts of carnosic acid, 0.2-0.5 parts of cassia seed extract, 0.1-0.3 parts of safflower extract, 0.2-0.4 parts of plantain seed extract, 0.1-0.2 parts of glutamine, 0.1-0.2 parts of arginine, 0.1-0.3 parts of astaxanthin, 0.2-0.3 parts of taurine, 0.5-1 parts of borneol, and 3-5 parts of glycerol.
[0007] The Chinese herbal medicine eye-improving health care patch containing a nitric oxide precursor not only utilizes the heating effect of far-infrared ceramic powder to regulate the opening and closing of skin pores, significantly improving the efficiency of medicinal ingredients penetrating into the skin; it also utilizes the stimulating effect of the magnetic field on eye acupuncture points, thereby promoting the absorption of medicinal ingredients by eye cells, significantly improving the utilization rate of medicinal ingredients; at the same time, through the coordinated effect of multiple raw materials, the effect of nitric oxide on the eyes is significantly enhanced; the eye-improving health care patch of the present invention significantly improves its treatment and relief effects on eye fatigue through the synergistic effect of magnetic powder, far-infrared ceramic powder and multiple raw materials, and is suitable for large-scale promotion and application.
[0008] Wherein, the nitric oxide precursor is a compound containing a diazeniumdiolate functional group; preferably, the nitric oxide precursor is diazeniumdiolate.
[0009] Wherein, the magnetic powder is ferroferric oxide powder.
[0010] The emission wavelength of the porous far-infrared ceramic powder is 10 μm-20 μm; preferably, the porosity of the porous far-infrared ceramic powder is 50-80%, the pore size is 0.1-2 μm; and the particle size is 0.1-1 mm.
[0011] The preparation method of the wild chrysanthemum extract comprises: crushing the wild chrysanthemum, adding cellulase and pectinase for enzymolysis; then adding ethanol solution for soaking, filtering and collecting the filtrate; adding organic solvent to the filtrate for extraction, taking the lower aqueous solution after standing, and concentrating it into a paste to obtain the wild chrysanthemum extract.
[0012] Preferably, the ratio of cellulase to pectinase is 1:1; the amount of cellulase and pectinase added is 0.5-1.5% of the wild chrysanthemum raw material; the temperature of enzymolysis is 30-38°C, and the time is 1-3h.
[0013] Preferably, in the ethanol solution, the concentration of ethanol is 50%; and the added amount is 5 times the weight of the wild chrysanthemum raw material.
[0014] Preferably, the organic solvent is dichloromethane or chloroform.
[0015] The preparation method of the safflower extract comprises: crushing the safflower, then soaking it in water, filtering and collecting the filtrate; adding ethanol to the filtrate for extraction, taking the upper ethanol solution after standing, concentrating and removing the ethanol into a paste to obtain the safflower extract.
[0016] The preparation method of the cassia seed extract comprises: high-temperature steaming the cassia seeds, then crushing them, adding cellulase and pectinase for enzymolysis, then extracting them with 75% ethanol solution, filtering and removing ethanol, and concentrating them into a paste to obtain the cassia seed extract.
[0017] Preferably, the high temperature cooking temperature is 120-130° C. and the time is 1-2 h.
[0018] Preferably, the ratio of cellulase to pectinase is 2:1; the amount of cellulase and pectinase added is 0.5-1.5% of the Cassia seed raw material; the temperature of enzymolysis is 35-40°C, and the time is 1-2h.
[0019] The preparation method of the psyllium seed extract comprises: low-temperature steaming the psyllium seed, then crushing it, extracting it with a 75% ethanol solution, filtering it to remove the ethanol, and concentrating it into a paste to obtain the psyllium seed extract.
[0020] Preferably, the low-temperature cooking temperature is 80-90° C. and the time is 3-4 hours.
[0021] In order to achieve the above-mentioned object of the invention, the present invention further provides a preparation process of a Chinese herbal medicine eye-improving health care patch containing a nitric oxide precursor, comprising the following steps:
[0022] (1) taurine, musk, menthol, frankincense, wild chrysanthemum extract, carnosic acid, cassia seed extract, safflower extract, plantain extract, glutamine, arginine, astaxanthin, taurine, borneol and magnetic powder are uniformly mixed to obtain a first mixture; nitric oxide precursor is first mixed with porous far-infrared ceramic powder to load the nitric oxide precursor into the pores of the porous far-infrared ceramic powder, and then mixed with glycerol to coat the porous far-infrared ceramic powder to obtain a second mixture;
[0023] (2) Loading the first mixture onto a first non-woven fabric, and loading the second mixture onto a second non-woven fabric; stacking the first non-woven fabric loaded with the first mixture and the second non-woven fabric loaded with the second mixture, and then sealing and packaging to obtain a Chinese herbal medicine eye health patch.
[0024] The method for using the Chinese herbal medicine eye-improving health care patch containing a nitric oxide precursor is as follows: applying the eye-improving health care patch to the eyes, peeling it off after the heat is gone, and continuing to close the eyes and rest for 2-5 minutes; 2-3 patches are applied daily, and half a month is one course of treatment.
[0025] Compared with the prior art, the present invention has the following beneficial effects:
[0026] 1. The Chinese herbal medicine eye-improving health care patch containing a nitric oxide precursor of the present invention utilizes the heating effect of far-infrared ceramic powder to regulate the opening and closing of skin pores and significantly improve the efficiency of medicinal ingredients penetrating into the skin.
[0027] 2. The Chinese herbal medicine eye-improving health care patch containing nitric oxide precursors of the present invention utilizes the stimulating effect of the magnetic field on the eye acupuncture points, thereby promoting the absorption of medicinal ingredients by eye cells and significantly improving the utilization rate of the medicinal ingredients.
[0028] 3. The Chinese herbal medicine eye-improving health care patch containing a nitric oxide precursor of the present invention significantly enhances the effect of nitric oxide on the eyes through the coordinated action of multiple raw materials.
[0029] 4. The Chinese herbal medicine eye-improving health care patch containing a nitric oxide precursor of the present invention significantly improves the treatment and relief effects of eye fatigue through the synergistic effect of magnetic powder, far-infrared ceramic powder and a variety of raw materials, and is suitable for large-scale promotion and application.
[0030] 5. The Chinese herbal medicine eye-improving health care patch containing nitric oxide precursors of the present invention can avoid the loss of nitric oxide precursors during storage through a special preparation process, thereby ensuring the efficacy of the Chinese herbal medicine eye-improving health care patch when in use. DETAILED DESCRIPTION
[0031] The present invention is further described in detail below in conjunction with test examples and specific implementation methods. However, this should not be understood as the scope of the above subject matter of the present invention being limited to the following embodiments, and all technologies realized based on the content of the present invention belong to the scope of the present invention.
[0032] Example 1
[0033] A Chinese herbal medicine eye-improving health care patch containing a nitric oxide precursor is prepared from the following raw materials in parts by weight: 5 parts of diazeniumdiolate, 12 parts of ferroferric oxide powder, 20 parts of porous far-infrared ceramic powder (with an emission wavelength of 10 μm-20 μm, a porosity of 70%, a pore size of 0.5 μm, and a particle size of 0.5 mm), 1 part of taurine, 0.3 parts of musk, 0.2 parts of menthol, 2 parts of frankincense, 0.3 parts of wild chrysanthemum extract, 0.1 parts of carnosic acid, 0.3 parts of cassia seed extract, 0.2 parts of safflower extract, 0.3 parts of plantain seed extract, 0.15 parts of glutamine, 0.15 parts of arginine, 0.2 parts of astaxanthin, 0.25 parts of taurine, 0.8 parts of borneol, and 4 parts of glycerol;
[0034] The preparation method of wild chrysanthemum extract comprises: crushing wild chrysanthemum, adding cellulase and pectinase (ratio of 1:1, dosage of 1%) for enzymolysis (temperature of 34°C, time of 2 hours); then adding ethanol solution (5 times; concentration of 50%) for soaking, filtering and collecting filtrate; adding organic solvent (dichloromethane) to the filtrate for extraction, taking the lower aqueous solution after standing, concentrating into a paste, and obtaining wild chrysanthemum extract;
[0035] The preparation method of safflower extract comprises: crushing safflower, then adding 5 times the weight of water to soak, filtering and collecting the filtrate; adding 2 times the weight of ethanol to the filtrate for extraction, taking the upper ethanol solution after standing, concentrating and removing the ethanol into a paste to obtain the safflower extract;
[0036] The preparation method of the psyllium seed extract comprises: steaming the psyllium seed at 85°C for 3 hours, then crushing it, extracting it with 5 times the weight of a 75% ethanol solution, removing the ethanol after filtering, and concentrating it into a paste to obtain the psyllium seed extract;
[0037] The preparation method of cassia seed extract comprises: high-temperature steaming of cassia seed (temperature is 125°C, time is 1 hour), then crushing, adding cellulase and pectinase (ratio is 2:1, dosage is 1%) for enzymatic hydrolysis (temperature is 38°C, time is 1.5 hours), then extracting with 75% ethanol solution, filtering to remove ethanol, and concentrating into a paste to obtain cassia seed extract.
[0038] A preparation process of a Chinese herbal medicine eye-improving health care patch containing a nitric oxide precursor comprises the following steps:
[0039] (1) taurine, musk, menthol, frankincense, wild chrysanthemum extract, carnosic acid, cassia seed extract, borneol and magnetic powder are uniformly mixed to obtain a first mixture; a nitric oxide precursor is first mixed with a porous far-infrared ceramic powder to load the nitric oxide precursor into the pores of the porous far-infrared ceramic powder, and then mixed with glycerol to coat the porous far-infrared ceramic powder to obtain a second mixture;
[0040] (2) Loading the first mixture onto a first non-woven fabric, and loading the second mixture onto a second non-woven fabric; stacking the first non-woven fabric loaded with the first mixture and the second non-woven fabric loaded with the second mixture, and then sealing and packaging to obtain a Chinese herbal medicine eye health patch.
[0041] Example 2
[0042] A Chinese herbal medicine eye-improving health care patch containing a nitric oxide precursor is prepared by the following raw materials in parts by weight: 6 parts of diazeniumdiolate, 15 parts of ferroferric oxide powder, 15 parts of porous far-infrared ceramic powder (with an emission wavelength of 10 μm-20 μm, a porosity of 80%, a pore size of 2 μm, and a particle size of 1 mm), 0.5 parts of taurine, 0.5 parts of musk, 0.3 parts of menthol, 3 parts of frankincense, 0.1 parts of wild chrysanthemum extract, 0.2 parts of carnosic acid, 0.2 parts of cassia seed extract, 0.1 parts of safflower extract, 0.2 parts of plantain seed extract, 0.2 parts of glutamine, 0.1 parts of arginine, 0.3 parts of astaxanthin, 0.2 parts of taurine, 1 part of borneol, and 3 parts of glycerol;
[0043] The preparation method of wild chrysanthemum extract comprises: crushing wild chrysanthemum, adding cellulase and pectinase (ratio of 1:1, dosage of 1.5%) for enzymolysis (temperature of 38°C, time of 1 hour); then adding ethanol solution (5 times; concentration of 50%) for soaking, filtering and collecting filtrate; adding organic solvent (chloroform) to the filtrate for extraction, taking the lower aqueous solution after standing, concentrating into a paste, and obtaining wild chrysanthemum extract;
[0044] The preparation method of safflower extract comprises: crushing safflower, then adding 5 times the weight of water to soak, filtering and collecting the filtrate; adding 2 times the weight of ethanol to the filtrate for extraction, taking the upper ethanol solution after standing, concentrating and removing the ethanol into a paste to obtain the safflower extract;
[0045] The preparation method of the psyllium seed extract comprises: steaming the psyllium seed at 85°C for 3 hours, then crushing it, extracting it with 5 times the weight of a 75% ethanol solution, removing the ethanol after filtering, and concentrating it into a paste to obtain the psyllium seed extract;
[0046] The preparation method of cassia seed extract comprises: high-temperature steaming of cassia seed (temperature is 130°C, time is 1 hour), then crushing, adding cellulase and pectinase (ratio is 2:1, dosage is 0.5%) for enzymatic hydrolysis (temperature is 35°C, time is 2 hours), then extracting with 75% ethanol solution, filtering to remove ethanol, and concentrating into a paste to obtain cassia seed extract.
[0047] A preparation process of a Chinese herbal medicine eye-improving health care patch containing a nitric oxide precursor comprises the following steps:
[0048] (1) taurine, musk, menthol, frankincense, wild chrysanthemum extract, carnosic acid, cassia seed extract, safflower extract, plantain extract, glutamine, arginine, astaxanthin, taurine, borneol and magnetic powder are uniformly mixed to obtain a first mixture; nitric oxide precursor is first mixed with porous far-infrared ceramic powder to load the nitric oxide precursor into the pores of the porous far-infrared ceramic powder, and then mixed with glycerol to coat the porous far-infrared ceramic powder to obtain a second mixture;
[0049] (2) Loading the first mixture onto a first non-woven fabric, and loading the second mixture onto a second non-woven fabric; stacking the first non-woven fabric loaded with the first mixture and the second non-woven fabric loaded with the second mixture, and then sealing and packaging to obtain a Chinese herbal medicine eye health patch.
[0050] Example 3
[0051] A Chinese herbal medicine eye-improving health care patch containing a nitric oxide precursor is prepared by the following raw materials in parts by weight: 3 parts of diazeniumdiolate, 10 parts of ferroferric oxide powder, 25 parts of porous far-infrared ceramic powder (with an emission wavelength of 10 μm-20 μm, a porosity of 50%, a pore size of 0.1 μm, and a particle size of 0.1 mm), 2 parts of taurine, 0.2 parts of musk, 0.3 parts of menthol, 1 part of frankincense, 0.5 parts of wild chrysanthemum extract, 0.1 parts of carnosic acid, 0.5 parts of cassia seed extract, 0.3 parts of safflower extract, 0.4 parts of plantain seed extract, 0.1 parts of glutamine, 0.2 parts of arginine, 0.1 parts of astaxanthin, 0.3 parts of taurine, 0.5 parts of borneol, and 3 parts of glycerol;
[0052] The preparation method of wild chrysanthemum extract comprises: crushing wild chrysanthemum, adding cellulase and pectinase (ratio of 1:1, dosage of 1.5%) for enzymolysis (temperature of 30°C, time of 3 hours); then adding ethanol solution (5 times; concentration of 50%) for soaking, filtering and collecting filtrate; adding organic solvent (dichloromethane) to the filtrate for extraction, taking the lower aqueous solution after standing, concentrating into a paste, and obtaining wild chrysanthemum extract;
[0053] The preparation method of safflower extract comprises: crushing safflower, then adding 5 times the weight of water to soak, filtering and collecting the filtrate; adding 2 times the weight of ethanol to the filtrate for extraction, taking the upper ethanol solution after standing, concentrating and removing the ethanol into a paste to obtain the safflower extract;
[0054] The preparation method of the psyllium seed extract comprises: steaming the psyllium seed at 80°C for 4 hours, then crushing it, extracting it with 5 times the weight of a 75% ethanol solution, filtering it to remove the ethanol, and concentrating it into a paste to obtain the psyllium seed extract;
[0055] The preparation method of cassia seed extract comprises: high-temperature steaming of cassia seed (temperature is 130°C, time is 1 hour), then crushing, adding cellulase and pectinase (ratio is 2:1, dosage is 0.5%) for enzymatic hydrolysis (temperature is 35°C, time is 2 hours), then extracting with 75% ethanol solution, filtering to remove ethanol, and concentrating into a paste to obtain cassia seed extract.
[0056] A preparation process of a Chinese herbal medicine eye-improving health care patch containing a nitric oxide precursor comprises the following steps:
[0057] (1) taurine, musk, menthol, frankincense, wild chrysanthemum extract, carnosic acid, cassia seed extract, safflower extract, plantain extract, glutamine, arginine, astaxanthin, taurine, borneol and magnetic powder are uniformly mixed to obtain a first mixture; nitric oxide precursor is first mixed with porous far-infrared ceramic powder to load the nitric oxide precursor into the pores of the porous far-infrared ceramic powder, and then mixed with glycerol to coat the porous far-infrared ceramic powder to obtain a second mixture;
[0058] (2) Loading the first mixture onto a first non-woven fabric, and loading the second mixture onto a second non-woven fabric; stacking the first non-woven fabric loaded with the first mixture and the second non-woven fabric loaded with the second mixture, and then sealing and packaging to obtain a Chinese herbal medicine eye health patch.
[0059] Embodiment 4:
[0060] A Chinese herbal medicine eye-improving health care patch containing a nitric oxide precursor is prepared by the following raw materials in parts by weight: 6 parts of diazeniumdiolate, 15 parts of ferroferric oxide powder, 15 parts of porous far-infrared ceramic powder (with an emission wavelength of 10 μm-20 μm, a porosity of 80%, a pore size of 2 μm, and a particle size of 1 mm), 0.5 parts of taurine, 0.5 parts of musk, 0.3 parts of menthol, 3 parts of frankincense, 0.1 parts of wild chrysanthemum extract, 0.2 parts of carnosic acid, 0.2 parts of cassia seed extract, 0.1 parts of safflower extract, 0.4 parts of plantain seed extract, 0.2 parts of glutamine, 0.1 parts of arginine, 0.2 parts of astaxanthin, 0.2 parts of taurine, 1 part of borneol, and 3 parts of glycerol;
[0061] The preparation method of wild chrysanthemum extract comprises: crushing wild chrysanthemum, adding cellulase and pectinase (ratio of 1:1, dosage of 1.5%) for enzymolysis (temperature of 30°C, time of 3 hours); then adding ethanol solution (5 times; concentration of 50%) for soaking, filtering and collecting filtrate; adding organic solvent (dichloromethane) to the filtrate for extraction, taking the lower aqueous solution after standing, concentrating into a paste, and obtaining wild chrysanthemum extract;
[0062] The preparation method of safflower extract comprises: crushing safflower, then adding 5 times the weight of water to soak, filtering and collecting the filtrate; adding 2 times the weight of ethanol to the filtrate for extraction, taking the upper ethanol solution after standing, concentrating and removing the ethanol into a paste to obtain the safflower extract;
[0063] The preparation method of the psyllium seed extract comprises: steaming the psyllium seed at 90° C. for 4 hours, then crushing it, extracting it with a 75% ethanol solution of 5 times its weight, removing the ethanol after filtering, and concentrating it into a paste to obtain the psyllium seed extract;
[0064] The preparation method of cassia seed extract comprises: high-temperature steaming of cassia seed (temperature is 125°C, time is 1 hour), then crushing, adding cellulase and pectinase (ratio is 2:1, dosage is 1%) for enzymatic hydrolysis (temperature is 38°C, time is 1.5 hours), then extracting with 75% ethanol solution, filtering to remove ethanol, and concentrating into a paste to obtain cassia seed extract.
[0065] A preparation process of a Chinese herbal medicine eye-improving health care patch containing a nitric oxide precursor comprises the following steps:
[0066] (1) taurine, musk, menthol, frankincense, wild chrysanthemum extract, carnosic acid, cassia seed extract, safflower extract, plantain extract, glutamine, arginine, astaxanthin, taurine, borneol and magnetic powder are uniformly mixed to obtain a first mixture; nitric oxide precursor is first mixed with porous far-infrared ceramic powder to load the nitric oxide precursor into the pores of the porous far-infrared ceramic powder, and then mixed with glycerol to coat the porous far-infrared ceramic powder to obtain a second mixture;
[0067] (2) Loading the first mixture onto a first non-woven fabric, and loading the second mixture onto a second non-woven fabric; stacking the first non-woven fabric loaded with the first mixture and the second non-woven fabric loaded with the second mixture, and then sealing and packaging to obtain a Chinese herbal medicine eye health patch.
Claims
1. A Chinese herbal medicine eye-improving health care patch containing a nitric oxide precursor, characterized in that: The invention comprises the following raw materials in parts by weight: 3-6 parts of nitric oxide precursor, 10-15 parts of magnetic powder, 15-25 parts of porous far-infrared ceramic powder, 0.5-2 parts of taurine, 0.2-0.5 parts of musk, 0.1-0.3 parts of menthol, 1-3 parts of frankincense, 0.1-0.5 parts of wild chrysanthemum extract, 0.1-0.2 parts of carnosic acid, 0.2-0. 5 parts of cassia seed extract, 0.1-0.3 parts of safflower extract, 0.2-0.4 parts of plantain seed extract, 0.1-0.2 parts of glutamine, 0.1-0.2 parts of arginine, 0.1-0.3 parts of astaxanthin, 0.2-0.3 parts of taurine, 0.5-1 parts of borneol, and 3-5 parts of glycerol; the nitric oxide precursor is a compound containing a diazeniumdiolate functional group.
2. The Chinese herbal medicine eye-improving health care patch according to claim 1, characterized in that: The nitric oxide precursor is diazeniumdiolate.
3. The Chinese herbal medicine eye-improving health care patch according to claim 1, characterized in that: The magnetic powder is ferroferric oxide powder.
4. The Chinese herbal medicine eye-improving health care patch according to claim 1, characterized in that: The emission wavelength of the porous far-infrared ceramic powder is 10 μm-20 μm.
5. The Chinese herbal medicine eye-improving health care patch according to claim 1, characterized in that: The porous far-infrared ceramic powder has a porosity of 50-80%, a pore size of 0.1-2 μm, and a particle size of 0.1-1 mm.
6. The Chinese herbal medicine eye-improving health care patch according to claim 1, characterized in that: The preparation method of the wild chrysanthemum extract comprises: crushing the wild chrysanthemum, adding cellulase and pectinase for enzymolysis; then adding ethanol solution for soaking, filtering and collecting the filtrate; adding organic solvent to the filtrate for extraction, taking the lower aqueous solution after standing, and concentrating it into a paste to obtain the wild chrysanthemum extract.
7. The Chinese herbal medicine eye-improving health care patch according to claim 6, characterized in that: The ratio of cellulase to pectinase is 1:1; the amount of cellulase and pectinase added is 0.5-1.5% of the wild chrysanthemum raw material; the temperature of enzymolysis is 30-38°C, and the time is 1-3h.
8. The Chinese herbal medicine eye-improving health care patch according to claim 6, characterized in that: In the ethanol solution, the concentration of ethanol is 50%; the added amount is 5 times the weight of the wild chrysanthemum raw material.
9. The Chinese herbal medicine eye-improving health care patch according to claim 1, characterized in that: The preparation method of the cassia seed extract comprises: steaming the cassia seeds at high temperature, then crushing them, adding cellulase and pectinase for enzymolysis, extracting them with 75% ethanol solution, removing ethanol after filtering, and concentrating them into a paste to obtain the cassia seed extract.
10. A process for preparing the Chinese herbal medicine eye-improving health care patch containing nitric oxide precursor according to any one of claims 1 to 9, characterized in that: The following steps are involved: (1) taurine, musk, menthol, frankincense, wild chrysanthemum extract, carnosic acid, cassia seed extract, safflower extract, plantain extract, glutamine, arginine, astaxanthin, taurine, borneol and magnetic powder are uniformly mixed to obtain a first mixture; nitric oxide precursor is first mixed with porous far-infrared ceramic powder to load the nitric oxide precursor into the pores of the porous far-infrared ceramic powder, and then mixed with glycerol to coat the porous far-infrared ceramic powder to obtain a second mixture; (2) loading the first mixture onto a first non-woven fabric, and loading the second mixture onto a second non-woven fabric; The first non-woven fabric loaded with the first mixture and the second non-woven fabric loaded with the second mixture are stacked and then sealed and packaged to obtain a Chinese herbal medicine eye-improving health care patch.
Citation Information
Patent Citations
Eyesight-improving health-care patch for improving eyes based on nitric oxide principle
CN107029037A