Head and neck anti-radiation coating agent for tumor radiotherapy and coating method thereof

Abstract

The invention discloses a head and neck radiation-proof coating agent for tumor radiotherapy. The raw materials comprise 50%-60% of aloe gel, 20%-30% of centella asiatica extract, 10%-15% of hyaluronic acid, 0.5%-1% of vitamin E, 0.5%-1% of green tea extract, 1%-2% of wool fat, 0.5% of polyethylene glycol, 1%-2% of superoxide dismutase, 1%-2% of epidermal active factors, 5% of beewax, 5% of saturated fatty acid and / or unsaturated fatty acid, 2% of potassium sorbate, 2% of SOD stabilizer and 1% of triethanolamine. 0.5% of methyl p-hydroxybenzoate; according to the invention, the centella asiatica extract and the saturated fatty acid and / or unsaturated fatty acid in the pigmentum are utilized to calm and diminish inflammation of the skin, so that irritation and damage of radiotherapy to the skin can be reduced, and meanwhile, part of radiation energy is effectively isolated, so that direct damage of radiation to skin cells is reduced; the skin barrier function is enhanced, inflammatory reactions such as skin redness and swelling and pain caused by radiotherapy can be relieved, and skin healing is promoted.

Description

Technical Field

[0001] The invention relates to the technical field of radiation protection coatings, in particular to a radiation protection coating for head and neck in tumor radiotherapy and a coating method thereof. Background Art

[0002] Radiotherapy is one of the important ways to treat malignant tumors. Radiotherapy mainly uses radiation to produce oxygen free radicals in tumor cells, thereby killing tumor cells. Radiation can also pass through the skin, and some skin cells are also highly sensitive to radioactivity, causing cell damage and radiation dermatitis.

[0003] Radiation protection coating is a composite preparation for external use. It can quickly and effectively penetrate the skin or wound surface, effectively remove a large number of free radicals generated by radiation on the irradiated skin surface, reduce the damage to skin and mucous membrane tissue caused by free radicals generated by factors such as radiotherapy, and increase the radiation damage tolerance dose of skin and mucous membranes, thereby protecting skin cells.

[0004] For example, the invention patent with the publication number (CN104000748B) discloses (a medical radiotherapy skin care agent and its production process), and the invention patent with the publication number (CN115487172B) discloses (an X-ray protective agent and its preparation method);

[0005] Although the above two types of ointments can remove a large number of free radicals generated by radiation on the surface of the irradiated skin and reduce the damage to the skin and mucous membrane tissues caused by free radicals generated by factors such as radiotherapy, they are unable to reduce the oxidative stress caused by radiation and inflammatory reactions such as skin redness, swelling, and pain. Therefore, they cause greater direct damage to skin cells and cannot promote skin healing. The skin is prone to discomfort, manifested as skin erythema and edema, and in more severe cases, peeling and even ulcers and necrosis may occur.

[0006] Therefore, a radiation protection coating for head and neck in tumor radiotherapy is proposed to solve this problem. Summary of the invention

[0007] The purpose of the present invention is to provide a radiation-proof coating for the head and neck for tumor radiotherapy, which solves the problem that the current radiation-proof coating causes a large oxidative stress reaction in patients after chemotherapy, easily destroys skin cells, and easily causes inflammatory reactions such as skin redness, swelling, pain, etc.

[0008] To achieve the above object, the present invention provides the following technical solution: a head and neck radiation protection coating for tumor radiotherapy, and the raw material ratio is as follows:

[0009] Aloe vera gel 50%-60%, Centella asiatica extract 20%-30%, hyaluronic acid 10%-15%, vitamin E 0.5%-1%, green tea extract 0.5%-1%, lanolin 1%-2%, polyethylene glycol 0.5%, superoxide dismutase 1%-2%, epidermal active factor 1%-2%, beeswax 5%, saturated fatty acids and / or unsaturated fatty acids 5%, potassium sorbate 2%, SOD stabilizer 2%, triethanolamine 1%, methylparaben 0.5%.

[0010] The hyaluronic acid may be replaced by 10% to 15% glycerin or 10% ceramide and 10% vaseline.

[0011] The saturated fatty acid is one or more of lard, mutton fat, fish oil and beef tallow.

[0012] The unsaturated fatty acid is one or more of olive oil, peanut oil, sesame oil, rapeseed oil, soybean oil, palm oil or castor oil.

[0013] A method for applying a radiation-proof coating for head and neck during tumor radiotherapy, comprising the following steps:

[0014] Step 1: Coating preparation: Proportion the above materials according to their proportions, and mix the proportioned materials into a coating for use;

[0015] Step 2: Skin cleaning: Before applying the lotion, the patient's head and neck skin needs to be cleaned to ensure that the skin is clean and dust-free. After cleaning, the patient lies flat on the chemotherapy bed and waits for the moisture to dry;

[0016] Step 3: Apply the ointment: Apply the ointment 15 to 30 minutes before radiotherapy. Apply an appropriate amount of the ointment to the head and neck area that needs to be protected. Do not apply it repeatedly and forcefully. Wait for it to dry naturally before performing radiotherapy.

[0017] Step 4: Reapply the ointment: During radiotherapy, patients who undergo long-term radiotherapy need to reapply the ointment regularly to maintain the protective effect on patients during radiotherapy. Generally, the ointment is reapplied 2-3 hours after radiotherapy.

[0018] Preferably, in step 2, after the patient has finished cleaning the head and neck area, a hair dryer can be used to accelerate the drying of moisture on the lens area, thereby reducing the waiting time before applying the ointment, so as to facilitate more efficient chemotherapy later.

[0019] Preferably, in step 3, before applying the lotion, it should be ensured that the patient has no allergic reaction to the ingredients of the lotion. And the spray should not replace other protective measures, such as wearing protective clothing or using shielding equipment, and a comprehensive protection strategy should always be implemented to ensure safety.

[0020] Preferably, in step 3, when applying the ointment, care should be taken to avoid contact between the ointment and the eyes and mucous membranes. If the ointment accidentally enters the eyes, it should be immediately rinsed with clean water. At the same time, when applying the ointment, medical staff should protect the wound of the patient at the application site to prevent the ointment from entering the wound.

[0021] Preferably, in the above step 3, after the medical staff has evenly applied the ointment, they need to gently massage the skin on the patient's head and neck where the ointment is applied to help it absorb quickly, and the massage time should be no less than 5 minutes.

[0022] Preferably, in step 4, the patient needs to pay attention to closely observe his or her own condition after applying the reagent, and communicate with the doctor in time if any obvious adverse reaction occurs, and actively cooperate with the doctor's examination and treatment.

[0023] Compared with the prior art, the present invention has the following beneficial effects:

[0024] The patent of the present invention adds vitamin E, green tea extract and hyaluronic acid to the coating. These antioxidant ingredients can not only neutralize free radicals and reduce the oxidative stress reaction caused by radiation, thereby protecting skin cells. At the same time, they can form a thin film on the skin surface, which can inhibit the loss of water in the stratum corneum, improve skin moisture retention, improve skin dryness, and reduce dryness, desquamation and other uncomfortable symptoms;

[0025] The present invention uses the Centella asiatica extract and saturated fatty acids and / or unsaturated fatty acids in the ointment to calm and reduce inflammation of the skin, thereby reducing the irritation and damage to the skin caused by radiotherapy, while effectively isolating part of the radiation energy, thereby reducing the direct damage of radiation to skin cells, enhancing the barrier function of the skin, reducing inflammatory reactions such as skin redness, swelling, and pain caused by radiotherapy, and promoting skin healing. DETAILED DESCRIPTION

[0026] The present invention will be described in more detail below by way of examples, which are merely illustrative and do not in any way limit the scope of the present invention.

[0027] In one aspect of the present invention, the present invention provides a technical solution: a radiation-proof coating for head and neck for tumor radiotherapy, the raw material ratio is as follows:

[0028] Aloe vera gel 50%-60%, Centella asiatica extract 20%-30%, hyaluronic acid 10%-15%, vitamin E 0.5%-1%, green tea extract 0.5%-1%, lanolin 1%-2%, polyethylene glycol 0.5%, superoxide dismutase 1%-2%, epidermal active factor 1%-2%, beeswax 5%, saturated fatty acids and / or unsaturated fatty acids 5%, potassium sorbate 2%, SOD stabilizer 2%, triethanolamine 1%, methylparaben 0.5%.

[0029] According to an embodiment of the present invention, the hyaluronic acid can be replaced with 10% to 15% glycerol or 10% ceramide and 10% vaseline. According to an embodiment of the present invention, hyaluronic acid, glycerol, ceramide and vaseline are added as needed to moisturize and protect the patient's skin, thereby meeting the usage conditions of different skins and ensuring the protective effect on the skin.

[0030] Hyaluronic acid is a substance that exists naturally in the human body. It has a water-locking effect, can inhibit the loss of water in the stratum corneum, and improve the moisturizing degree of the skin.

[0031] Glycerin is a common moisturizing ingredient that absorbs moisture from the air and locks in moisture. It is suitable for symptoms such as itching and chapped skin caused by dryness.

[0032] Ceramide can strengthen the skin barrier function and reduce water loss, and is suitable for sensitive skin and dry skin;

[0033] Vaseline can form a protective film on the skin surface to prevent moisture loss. It is suitable for dry skin and skin that needs to repair the barrier.

[0034] According to an embodiment of the present invention, the saturated fatty acid is one or more of lard, sheep oil, fish oil, and beef tallow. According to an embodiment of the present invention, the coating is made into a relatively soft oily ointment using animal oil, which contains saturated fatty acids, is not only more friendly to the patient's skin, but also convenient for medical staff to apply, and does not evaporate water, and does not cause a drop in local temperature. At the same time, after the coating is cleaned off, a very thin layer of protective oil film is still left on the skin surface, which is conducive to promoting continuous skin repair.

[0035] Lard is the fat extracted from pigs, also known as animal fat or pig fat. It is characterized by high saturated fatty acid content, high melting point, and solid at room temperature.

[0036] Sheep fat is the fat extracted from sheep. It is hard and not easy to oxidize, so it is suitable for long-term storage.

[0037] Fish oil is a kind of oil extracted from fish. It is rich in unsaturated fatty acids and Omega-3 fatty acids, which helps lower cholesterol and prevent cardiovascular and cerebrovascular diseases. Fish oil can lower blood lipids, prevent cardiovascular diseases and brain function decline;

[0038] Butter is the fat extracted from cattle, which also contains high saturated fatty acids, has a high melting point, and is solid at room temperature;

[0039] According to an embodiment of the present invention, the unsaturated fatty acid is one or more of olive oil, peanut oil, sesame oil, rapeseed oil, soybean oil, palm oil or castor oil. According to an embodiment of the present invention, the coating is made into a relatively soft oily ointment using vegetable oil, which contains unsaturated fatty acids, is not only more friendly to the patient's skin, but also convenient for medical staff to apply, and does not evaporate water, and will not cause a drop in local temperature. At the same time, after the coating is cleaned off, a very thin layer of protective oil film is still left on the skin surface, which is conducive to promoting continuous skin repair.

[0040] Olive oil is directly cold-pressed from fresh olive fruits without heating or chemical treatment, retaining its natural nutrients and containing high levels of unsaturated fatty acids. Olive oil is considered to be the most suitable oil for human nutrition discovered so far, and has extremely high natural health and beauty effects;

[0041] Peanut oil is pressed from peanuts and is rich in monounsaturated and polyunsaturated fatty acids;

[0042] Sesame oil usually refers to sesame oil, which is pressed from sesame seeds, has a strong aroma, and contains natural antioxidants such as sesamol and sesamin;

[0043] Rapeseed oil has a unique fragrance and is pressed from rapeseed. It is rich in vitamin E, carotene and phospholipids.

[0044] Soybean oil is pressed from soybeans and is rich in vitamin E and lecithin;

[0045] Palm oil is squeezed from the fruit of palm trees and contains high levels of unsaturated fatty acids.

[0046] Castor oil is a vegetable oil extracted from castor seeds. Castor oil is composed of 80% to 85% ricinoleic acid, 7% oleic acid, 3% linoleic acid, 2% palmitic acid, and 1% stearic acid. It is flammable but not non-flammable, soluble in ethanol, slightly soluble in aliphatic hydrocarbons, almost insoluble in water, and slightly volatile.

[0047] Preparation method

[0048] In the second aspect of the present invention, the present invention provides a method for preparing the radiation protection coating described above, the method comprising: first preparing the coating: proportioning the above materials according to the ratio, and mixing the proportioned materials into a coating for use; then cleaning the skin: before applying the coating, the skin of the patient's head and neck needs to be cleaned to ensure that the skin is clean and dust-free. After cleaning, the patient lies flat on the chemotherapy bed and waits for the moisture to dry; then apply the coating: use the coating 15 to 30 minutes before radiotherapy. Take an appropriate amount of the above coating to the head and neck area that the patient needs to protect and spread it evenly. Do not apply it repeatedly and forcefully. After that, wait for it to dry naturally before performing radiotherapy operations; finally, apply the coating as needed: during radiotherapy, for patients who undergo radiotherapy for a long time, it is necessary to regularly apply the coating to maintain the protective effect on the patient during radiotherapy. Generally, the coating is applied 2-3 hours after radiotherapy.

[0049] The patent of the present invention adds vitamin E, green tea extract and hyaluronic acid to the coating. These antioxidant ingredients can not only neutralize free radicals and reduce the oxidative stress reaction caused by radiation, thereby protecting skin cells, but also form a thin film on the skin surface, which can inhibit the loss of water in the stratum corneum, improve skin moisture retention, improve skin dryness, and reduce dryness, desquamation and other uncomfortable symptoms.

[0050] The present invention uses the Centella asiatica extract and saturated fatty acids and / or unsaturated fatty acids in the ointment to calm and reduce inflammation of the skin, thereby reducing the irritation and damage to the skin caused by radiotherapy, while effectively isolating part of the radiation energy, thereby reducing the direct damage of radiation to skin cells, enhancing the barrier function of the skin, reducing inflammatory reactions such as skin redness, swelling, and pain caused by radiotherapy, and promoting skin healing.

[0051] According to an embodiment of the present invention, the coating is first prepared: the materials are proportioned according to the ratio, and the proportioned materials are mixed and processed into a coating for use; then the skin is cleaned: the skin of the patient's head and neck needs to be cleaned before applying the coating to ensure that the skin is clean and dust-free. After the cleaning is completed, the patient lies flat on the chemotherapy bed and waits for the moisture to dry; during the skin cleaning process, a hair dryer can be used to accelerate the drying of the moisture in the lens area, thereby reducing the waiting time before applying the coating, so that chemotherapy can be performed more efficiently later; then the coating is applied again: before radiotherapy, the coating is used 15 to 30 minutes in advance. Take an appropriate amount of the above coating to the head and neck area that the patient needs to protect and spread it evenly. Do not apply it repeatedly and forcefully. After that, wait for it to dry naturally before performing radiotherapy operations; finally, apply the coating as needed: during radiotherapy, for patients who undergo radiotherapy for a long time, it is necessary to regularly apply the coating to maintain the protective effect on the patient during radiotherapy. Generally, the coating is applied 2-3 hours after radiotherapy.

[0052] According to an embodiment of the present invention, the coating is first prepared: the materials are proportioned according to the ratio, and the proportioned materials are mixed and processed into a coating for use; then the skin is cleaned: the skin of the patient's head and neck needs to be cleaned before applying the coating to ensure that the skin is clean and dust-free. After the cleaning is completed, the patient lies flat on the chemotherapy bed and waits for the moisture to dry; during the skin cleaning process, a hair dryer can be used to accelerate the drying of the moisture on the lens part, thereby reducing the waiting time before applying the coating, so that chemotherapy can be performed more efficiently later; then the coating is applied: before radiotherapy, the coating is used 15 to 30 minutes in advance. Take an appropriate amount of the above coating and apply it evenly to the head and neck area of ​​the patient that needs to be protected. Do not apply it repeatedly and forcefully. After that, wait for it to dry naturally before performing radiotherapy operations; before applying the coating, it should be ensured that the patient has no allergic reaction to the ingredients of the coating. And the spray should not replace other protective measures, such as wearing protective clothing or using shielding equipment. A comprehensive protection strategy should always be implemented to ensure safety. Finally, reapply the spray as needed: During radiotherapy, patients undergoing long-term radiotherapy need to reapply the spray regularly to maintain the protective effect on the patients during radiotherapy. Generally, reapply the spray 2-3 hours after radiotherapy.

[0053] According to an embodiment of the present invention, the coating is first prepared: the materials are proportioned according to the ratio, and the proportioned materials are mixed and processed into a coating for use; then the skin is cleaned: the skin of the patient's head and neck needs to be cleaned before applying the coating to ensure that the skin is clean and dust-free. After the cleaning is completed, the patient lies flat on the chemotherapy bed and waits for the moisture to dry; during the skin cleaning process, a hair dryer can be used to accelerate the drying of the moisture in the lens part, thereby reducing the waiting time before applying the coating, so that chemotherapy can be carried out more efficiently later; then the coating is applied: before radiotherapy, the coating is used 15 to 30 minutes in advance. Take an appropriate amount of the above coating to the head and neck part of the patient that needs to be protected and apply it evenly. Do not apply it repeatedly and forcefully. After that, wait for it to dry naturally before performing radiotherapy operations; before applying the coating, it should be ensured that the patient has no allergic reaction to the ingredients of the coating. In addition, the spray should not replace other protective measures, such as wearing protective clothing or using shielding equipment, and a comprehensive protection strategy should always be implemented to ensure safety; during the application of the coating, care should be taken to avoid contact between the coating and the eyes and mucous membranes. If it accidentally enters the eyes, it should be rinsed immediately with clean water. At the same time, when applying the ointment, medical staff should protect the patient's wound at the application site to prevent the ointment from entering the wound; finally, reapply the ointment as needed: During radiotherapy, patients undergoing long-term radiotherapy need to reapply the ointment regularly to maintain the protective effect on the patient during radiotherapy. Generally, reapply the ointment 2-3 hours after radiotherapy.

[0054] According to an embodiment of the present invention, the coating is first prepared: the materials are proportioned according to the ratio, and the proportioned materials are mixed and processed into a coating for use; then the skin is cleaned: the skin of the patient's head and neck needs to be cleaned before applying the coating to ensure that the skin is clean and dust-free. After the cleaning is completed, the patient lies flat on the chemotherapy bed and waits for the moisture to dry; during the skin cleaning process, a hair dryer can be used to accelerate the drying of the moisture in the lens part, thereby reducing the waiting time before applying the coating, so that chemotherapy can be carried out more efficiently later; then the coating is applied: before radiotherapy, the coating is used 15 to 30 minutes in advance. Take an appropriate amount of the above coating to the head and neck part of the patient that needs to be protected and apply it evenly. Do not apply it repeatedly and forcefully. After that, wait for it to dry naturally before performing radiotherapy operations; before applying the coating, it should be ensured that the patient has no allergic reaction to the ingredients of the coating. In addition, the spray should not replace other protective measures, such as wearing protective clothing or using shielding equipment, and a comprehensive protection strategy should always be implemented to ensure safety; during the application of the coating, care should be taken to avoid contact between the coating and the eyes and mucous membranes. If it accidentally enters the eyes, it should be rinsed immediately with clean water. At the same time, when applying the ointment, medical staff should protect the patient's wound at the application site to prevent the ointment from entering the wound; after the medical staff has applied the ointment evenly, they need to gently massage the skin on the patient's head and neck where the ointment is applied to help it absorb quickly. The massage should last no less than 5 minutes; finally, reapply the ointment as needed: During radiotherapy, patients undergoing long-term radiotherapy need to reapply the ointment regularly to maintain the protective effect on the patient during radiotherapy. Generally, reapply the ointment 2-3 hours after radiotherapy.

[0055] According to an embodiment of the present invention, the coating is first prepared: the materials are proportioned according to the ratio, and the proportioned materials are mixed and processed into a coating for use; then the skin is cleaned: the skin of the patient's head and neck needs to be cleaned before applying the coating to ensure that the skin is clean and dust-free. After the cleaning is completed, the patient lies flat on the chemotherapy bed and waits for the moisture to dry; during the skin cleaning process, a hair dryer can be used to accelerate the drying of the moisture in the lens part, thereby reducing the waiting time before applying the coating, so that chemotherapy can be carried out more efficiently later; then the coating is applied: before radiotherapy, the coating is used 15 to 30 minutes in advance. Take an appropriate amount of the above coating to the head and neck part of the patient that needs to be protected and apply it evenly. Do not apply it repeatedly and forcefully. After that, wait for it to dry naturally before performing radiotherapy operations; before applying the coating, it should be ensured that the patient has no allergic reaction to the ingredients of the coating. In addition, the spray should not replace other protective measures, such as wearing protective clothing or using shielding equipment, and a comprehensive protection strategy should always be implemented to ensure safety; during the application of the coating, care should be taken to avoid contact between the coating and the eyes and mucous membranes. If it accidentally enters the eyes, it should be rinsed immediately with clean water. At the same time, when applying the ointment, medical staff should protect the patient's wound at the application site to prevent the ointment from entering the wound; after the medical staff has applied the ointment evenly, they need to gently massage the skin on the patient's head and neck where the ointment is applied to help it absorb quickly. The massage should last no less than 5 minutes; finally, reapply the ointment as needed: During radiotherapy, patients who undergo long-term radiotherapy need to reapply the ointment regularly to maintain the protective effect on the patient during radiotherapy, generally reapply the ointment 2-3 hours after radiotherapy; after applying the reagent, the patient needs to pay attention to closely observe his or her own condition. If any obvious adverse reactions occur, he or she needs to communicate with the doctor in a timely manner, and actively cooperate with the doctor's examination and treatment.

Claims

1. A radiation protection coating for head and neck for tumor radiotherapy, characterized in that: The raw material ratio is as follows: Aloe vera gel 50%-60%, Centella asiatica extract 20%-30%, hyaluronic acid 10%-15%, vitamin E 0.5%-1%, green tea extract 0.5%-1%, lanolin 1%-2%, polyethylene glycol 0.5%, superoxide dismutase 1%-2%, epidermal active factor 1%-2%, beeswax 5%, saturated fatty acids and / or unsaturated fatty acids 5%, potassium sorbate 2%, SOD stabilizer 2%, triethanolamine 1%, methylparaben 0.5%.

2. The head and neck radiation protection coating for tumor radiotherapy according to claim 1, characterized in that: The hyaluronic acid may be replaced by 10% to 15% glycerin or 10% ceramide and 10% vaseline.

3. The head and neck radiation protection coating for tumor radiotherapy according to claim 1, characterized in that: The saturated fatty acid is one or more of lard, mutton fat, fish oil and beef tallow.

4. The head and neck radiation protection coating for tumor radiotherapy according to claim 1, characterized in that: The unsaturated fatty acid is one or more of olive oil, peanut oil, sesame oil, rapeseed oil, soybean oil, palm oil or castor oil.

5. A method for applying a radiation-proof coating for head and neck for tumor radiotherapy, according to any one of claims 1 to 4, characterized in that: The following steps are involved: Step 1: Coating preparation: Proportion the above materials according to their proportions, and mix the proportioned materials into a coating for use; Step 2: Skin cleaning: Before applying the lotion, the patient's head and neck skin needs to be cleaned to ensure that the skin is clean and dust-free. After cleaning, the patient lies flat on the chemotherapy bed and waits for the moisture to dry; Step 3: Apply the ointment: Apply the ointment 15 to 30 minutes before radiotherapy. Apply an appropriate amount of the ointment to the head and neck area that needs to be protected. Do not apply it repeatedly and forcefully. Wait for it to dry naturally before performing radiotherapy. Step 4: Reapply the ointment: During radiotherapy, patients who undergo long-term radiotherapy need to reapply the ointment regularly to maintain the protective effect on patients during radiotherapy. Generally, the ointment is reapplied 2-3 hours after radiotherapy.

6. The method for applying the radiation protection coating for head and neck for tumor radiotherapy according to claim 5, characterized in that: In step 2, after the patient has finished cleaning the head and neck, a hair dryer can be used to accelerate the drying of moisture on the lens area, thereby reducing the waiting time before applying the ointment, so that subsequent chemotherapy can be carried out more efficiently.

7. The method for applying the radiation protection coating for head and neck for tumor radiotherapy according to claim 5, characterized in that: In step 3, before applying the lotion, it should be ensured that the patient has no allergic reaction to the ingredients of the lotion. And the spray should not replace other protective measures, such as wearing protective clothing or using shielding equipment, and a comprehensive protection strategy should always be implemented to ensure safety.

8. The method for applying the radiation protection coating for head and neck for tumor radiotherapy according to claim 5, characterized in that: In step 3, when applying the ointment, care should be taken to avoid contact between the ointment and the eyes and mucous membranes. If the ointment accidentally enters the eyes, it should be immediately rinsed with clean water. At the same time, when applying the ointment, medical staff should protect the wound of the patient to prevent the ointment from entering the wound.

9. The method for applying the head and neck radiation protection coating for tumor radiotherapy according to claim 5, characterized in that: In step 3, after the medical staff has evenly applied the ointment, they need to gently massage the skin on the patient's head and neck where the ointment is applied to help it absorb quickly, and the massage time should be no less than 5 minutes.

10. The method for applying the radiation protection coating for head and neck for tumor radiotherapy according to claim 5, characterized in that: In step 4, the patient needs to pay close attention to observing his or her own condition after applying the reagent. If any obvious adverse reaction occurs, the patient needs to communicate with the doctor in a timely manner and actively cooperate with the doctor's examination and treatment.