Giant salamander polypeptide powder composition formula for immunoregulation

Abstract

The invention belongs to the field of polypeptide powder, and particularly relates to a giant salamander polypeptide powder composition formula for immunoregulation, which comprises 10-20 parts of giant salamander polypeptide powder, 30-40 parts of oyster polypeptide, 15-25 parts of soybean polypeptide, 5-15 parts of Chinese yam powder, 6-14 parts of apple powder, 4-16 parts of Chinese wolfberry fruit powder, 5-14 parts of sea buckthorn fruit powder, 22-36 parts of fructo-oligosaccharide, 5-13 parts of water-soluble dietary fiber and 1-8 parts of stevioside. The giant salamander polypeptide small molecule peptide in the composition is high in proportion, and the giant salamander polypeptide composition contains metallothionein (MT) and has the effects of expelling toxins by heavy metals and delaying senescence. The giant salamander protein and amino acid composition proportion is basically consistent with human beings, and can be easily absorbed by human bodies. The components of arginine, glutamine, leucine and the like can effectively enhance the immune function of a patient and reduce the occurrence rate of postoperative infection. In addition, the composition also contains DHA and phosphatidylserine, and is especially suitable for people who need to quickly recover physique after an operation, people with cardiovascular and cerebrovascular diseases and people with low immunity in a high-pressure working environment.

Description

Technical Field

[0001] The invention belongs to the field of polypeptide powder, in particular to a formula of a giant salamander polypeptide powder composition for immunomodulation. Background Art

[0002] As a rare and precious product unique to my country, the giant salamander occupies a unique position in the fields of biodiversity and traditional medicine. It mainly inhabits streams in the middle and upper reaches of the Yangtze River, the middle and upper reaches of the Pearl River, and the upper reaches of the Han River.

[0003] At present, the annual breeding capacity has climbed to 600,000, and the breeding scale has achieved a leap-forward development. However, behind the booming industry, the problem of deep processing and utilization of giant salamander resources has gradually become prominent, becoming a key bottleneck restricting the continued development of the giant salamander industry, which urgently needs to be broken through.

[0004] As social economy continues to improve, people are paying more and more attention to their own health. Taking the postoperative patients as an example, surgical trauma will significantly weaken the body's immune regulation ability, and it is very easy to cause postoperative infection if you are not careful, which will seriously affect the recovery process and quality of life. At the same time, people in high-pressure working environments face high-intensity work pressure for a long time, high mental tension, and irregular work and rest, which leads to generally weak immune regulation ability and a greatly increased risk of illness. The market is in urgent need of products that can effectively enhance immune regulation ability.

[0005] To this end, the present invention provides a formula of a giant salamander polypeptide powder composition for immunomodulation. Summary of the invention

[0006] In order to make up for the deficiencies of the prior art, at least one technical problem raised in the background technology is solved.

[0007] The technical solution adopted by the present invention to solve the technical problem is: the formula of the giant salamander polypeptide powder composition for immunomodulation described in the present invention is characterized by comprising the following components in parts by weight:

[0008] 10-20 parts of giant salamander polypeptide powder, which is prepared by a specific process and is rich in a variety of bioactive peptides and has significant immunomodulatory potential;

[0009] 30-40 servings of oyster peptides, which are extracted from high-quality oysters and contain a variety of amino acids and functional ingredients, which help enhance immune regulation.

[0010] 15-25 parts of soybean peptides. Soy peptides are derived from the hydrolysis of soybean protein. They are easy to absorb and have high biological activity, and play a synergistic role in overall immune regulation.

[0011] 5-15 portions of yam powder. The yam powder is finely ground to retain a variety of nutrients in the yam, providing gentle nourishment for immune regulation;

[0012] 6-14 servings of apple powder. Apple powder is made from high-quality apples and is rich in vitamins, minerals, pectin, etc., which can help improve the body's immune vitality;

[0013] 4-16 servings of wolfberry powder. Wolfberry powder is processed from natural wolfberries. The wolfberry polysaccharides it contains play a positive role in immune regulation.

[0014] 5-14 parts of seabuckthorn fruit powder. Seabuckthorn fruit powder is extracted from seabuckthorn fruit and is rich in various bioactive substances, which can enhance the immune regulation effect;

[0015] 22-36 parts of oligofructose. As a prebiotic, oligofructose can regulate intestinal flora and indirectly promote the body's immune regulation function;

[0016] 5-13 servings of water-soluble dietary fiber, which helps maintain intestinal health and intestinal barrier function, thus having a positive impact on immune regulation;

[0017] 1-8 parts of stevioside are used to adjust the taste and improve the palatability of the product without adding too much calories.

[0018] A preparation process of a giant salamander polypeptide powder composition formula for immunomodulation, the preparation process comprising the following steps:

[0019] S1: Pretreatment: Select healthy giant salamanders, first use a specific cleaning method to remove the mucus on their body surface, then use precise cutting techniques to cut open the neck of the giant salamander to bleed, collect the blood and freeze it, then remove the giant salamander meat, and properly freeze the head, tail and limbs for later use;

[0020] S2: Grinding: Put the pre-treated giant salamander meat into a universal grinder, grind it into uniform meat pieces, and prepare it into liquid according to a specific ratio to ensure the smooth progress of the subsequent enzymatic hydrolysis process;

[0021] S3: Enzyme hydrolysis: Add enzymes of specific types and proportions to the feed solution, perform enzymolysis reaction at a temperature range of 45-60°C for 2-8 hours, and obtain high-quality enzymolysis solution after the enzymolysis is completed;

[0022] S4: Centrifugation: Place the enzymatic hydrolysate into a centrifuge, set the speed to 4000-20000 r / min, and perform centrifugation for 3-10 minutes to achieve solid-liquid separation;

[0023] S5: Concentration: The supernatant produced by the centrifuge is concentrated by a professional concentrator. The temperature of the concentrator is set at 50-55°C, the pressure is maintained at -0.1Mpa, and the condensation temperature is controlled at 10-11°C;

[0024] S6: Spray drying: The concentrated supernatant material is atomized and sent to a drying chamber. During the process of full contact with hot air, the water vaporizes rapidly, and finally dry giant salamander polypeptide powder is obtained.

[0025] Furthermore, in step S1, the bloodletting operation uses professional tools and processes to ensure that the blood is collected completely, and the freezing temperature of the collected blood is controlled below -18°C to maintain the stability of the bioactive substances in the blood.

[0026] Furthermore, the ratio of the liquid, water and minced meat in step S3 is strictly controlled at 1:1-6, and the amount of enzyme added during the enzymatic hydrolysis is precisely controlled at 0.3-1.2%, thereby ensuring that the enzymatic hydrolysis reaction is efficient and sufficient.

[0027] Furthermore, in step S6, the content of the material entering the spray drying process is stabilized at 5-20%, the inlet temperature of the drying chamber is maintained at 120-170°C, and the outlet temperature is maintained at 70-95°C, to ensure the quality and activity of the giant salamander polypeptide powder.

[0028] The beneficial effects of the present invention are as follows:

[0029] A kind of giant salamander polypeptide powder composition formula for immunomodulation described in the present invention, the giant salamander polypeptide small molecule peptide in the composition accounts for a high proportion, and contains metallothionein (MT), has the effect of heavy metal detoxification and anti-aging. The composition ratio of giant salamander protein and amino acid is basically the same as that of humans, and is easily absorbed by the human body. The ingredients such as arginine, glutamine and leucine therein can effectively enhance the patient's immune function and reduce the incidence of postoperative infection. In addition, the composition also contains DHA and phosphatidylserine, which is particularly suitable for people who need to quickly recover their physical fitness after surgery, sub-healthy groups, people with cardiovascular and cerebrovascular diseases, and people with low immunity under high-pressure working environment. At the same time, the composition can also prevent Alzheimer's disease and memory degradation, significantly improve the immune regulation ability of the human body, and provide a strong guarantee for the health of different groups of people. DETAILED DESCRIPTION

[0030] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further explained below in conjunction with specific implementation methods.

[0031] A formula of a giant salamander polypeptide powder composition for immunomodulation according to an embodiment of the present invention is characterized by comprising the following components in parts by weight:

[0032] 10-20 parts of giant salamander polypeptide powder, which is prepared by a specific process and is rich in a variety of bioactive peptides and has significant immunomodulatory potential;

[0033] 30-40 servings of oyster peptides, which are extracted from high-quality oysters and contain a variety of amino acids and functional ingredients, which help enhance immune regulation.

[0034] 15-25 parts of soybean peptides. Soy peptides are derived from the hydrolysis of soybean protein. They are easy to absorb and have high biological activity, and play a synergistic role in overall immune regulation.

[0035] 5-15 portions of yam powder. The yam powder is finely ground to retain a variety of nutrients in the yam, providing gentle nourishment for immune regulation;

[0036] 6-14 servings of apple powder. Apple powder is made from high-quality apples and is rich in vitamins, minerals, pectin, etc., which can help improve the body's immune vitality;

[0037] 4-16 servings of wolfberry powder. Wolfberry powder is processed from natural wolfberries. The wolfberry polysaccharides it contains play a positive role in immune regulation.

[0038] 5-14 parts of seabuckthorn fruit powder. Seabuckthorn fruit powder is extracted from seabuckthorn fruit and is rich in various bioactive substances, which can enhance the immune regulation effect;

[0039] 22-36 parts of oligofructose. As a prebiotic, oligofructose can regulate intestinal flora and indirectly promote the body's immune regulation function;

[0040] 5-13 servings of water-soluble dietary fiber, which helps maintain intestinal health and intestinal barrier function, thus having a positive impact on immune regulation;

[0041] 1-8 parts of stevioside are used to adjust the taste and improve the palatability of the product without adding too much calories.

[0042] A preparation process of a giant salamander polypeptide powder composition formula for immunomodulation, the preparation process comprising the following steps:

[0043] S1: Pretreatment: Select healthy giant salamanders, first use a specific cleaning method to remove the mucus on their body surface, then use precise cutting techniques to cut open the neck of the giant salamander to bleed, collect the blood and freeze it, then remove the giant salamander meat, and properly freeze the head, tail and limbs for later use;

[0044] S2: Grinding: Put the pre-treated giant salamander meat into a universal grinder, grind it into uniform meat pieces, and prepare it into liquid according to a specific ratio to ensure the smooth progress of the subsequent enzymatic hydrolysis process;

[0045] S3: Enzyme hydrolysis: Add enzymes of specific types and proportions to the feed solution, perform enzymolysis reaction at a temperature range of 45-60°C for 2-8 hours, and obtain high-quality enzymolysis solution after the enzymolysis is completed;

[0046] S4: Centrifugation: Place the enzymatic hydrolysate into a centrifuge, set the speed to 4000-20000 r / min, and perform centrifugation for 3-10 minutes to achieve solid-liquid separation;

[0047] S5: Concentration: The supernatant produced by the centrifuge is concentrated by a professional concentrator. The temperature of the concentrator is set at 50-55°C, the pressure is maintained at -0.1Mpa, and the condensation temperature is controlled at 10-11°C;

[0048] S6: Spray drying: The concentrated supernatant material is atomized and sent to a drying chamber. During the process of full contact with hot air, the water vaporizes rapidly, and finally dry giant salamander polypeptide powder is obtained.

[0049] In the S1 step, the bloodletting operation uses professional tools and processes to ensure that the blood is collected completely, and the freezing temperature of the collected blood is controlled below -18°C to maintain the stability of the bioactive substances in the blood.

[0050] The ratio of the liquid, water and minced meat in step S3 is strictly controlled at 1:1-6, and the amount of enzyme added during the enzymatic hydrolysis is precisely controlled at 0.3-1.2%, so as to ensure that the enzymatic hydrolysis reaction is efficient and sufficient.

[0051] In step S6, the content of the material entering the spray drying process is stabilized at 5-20%, the inlet temperature of the drying chamber is maintained at 120-170° C., and the outlet temperature is maintained at 70-95° C., ensuring the quality and activity of the giant salamander polypeptide powder.

[0052] Embodiment 1

[0053] The components of the formula of the giant salamander polypeptide powder composition for immunomodulation are as follows by weight:

[0054] 13 servings of giant salamander polypeptide powder: Giant salamander polypeptide powder is one of the core ingredients of the composition, rich in a variety of bioactive peptides that are beneficial to the human body. These active peptides play a key role in immune regulation.

[0055] 32 servings of Oyster Peptide: Oyster peptide extracted from high-quality oysters, rich in amino acids and functional ingredients, can work synergistically with other ingredients such as giant salamander peptide to further enhance the immunomodulatory effect of the combination.

[0056] 18 servings of soy peptides: Soy peptides are obtained by hydrolyzing soy protein. They are easily absorbed and have high biological activity. They help improve the body's utilization efficiency of nutrients and play a positive role in overall immune regulation.

[0057] 8 servings of yam powder: Yam powder is made from high-quality yam through fine grinding, retaining a variety of nutrients in yam, such as polysaccharides, saponins, etc. These ingredients have a mild tonic effect and provide a good foundation for immune regulation.

[0058] 9 servings of apple powder: Apple powder is made from fresh apples and is rich in nutrients such as vitamins, minerals, and pectin. It helps maintain normal intestinal function and indirectly enhances the body's immune activity.

[0059] 7 portions of wolfberry powder: Wolfberry powder is made from natural wolfberries. The biologically active ingredients it contains, such as wolfberry polysaccharides, have significant effects in regulating the body's immune function and anti-oxidation.

[0060] 8.5 parts of seabuckthorn fruit powder: Seabuckthorn fruit powder is extracted from seabuckthorn fruit. Seabuckthorn is rich in various bioactive substances, such as vitamin C, carotenoids, etc., which can enhance the immunomodulatory effect of the composition.

[0061] 27 parts of oligofructose: As a prebiotic, oligofructose can regulate the balance of intestinal flora and promote the growth and reproduction of beneficial bacteria, thereby indirectly affecting the body's immune regulation function.

[0062] 8 servings of water-soluble dietary fiber: Water-soluble dietary fiber helps increase intestinal motility, maintain intestinal barrier function, plays an important role in intestinal health, and thus has a positive impact on overall immune regulation.

[0063] 3 parts of stevioside: Stevioside is used to adjust the taste of the composition, improve the palatability of the product without adding too much calories, and make it easier for consumers to accept.

[0064] Preparation technology of giant salamander polypeptide powder

[0065] The preparation of the giant salamander polypeptide powder in this embodiment adopts a set of scientific and rigorous processes, and the specific steps are as follows:

[0066] S1: Preprocessing

[0067] A healthy giant salamander is selected, and a specific cleaning method is first used to remove the mucus on its body surface to ensure the hygiene and quality of the subsequent processing process. Then, a sharp knife is used to accurately cut the neck of the giant salamander for bleeding. At the same time, the blood is collected and immediately frozen for possible subsequent research or application. After the bleeding is completed, the meat of the giant salamander is carefully removed, and the remaining head, tail and limbs are properly frozen for later use, so as to make full use of all parts of the giant salamander.

[0068] S2: Smash

[0069] Put the pre-treated giant salamander meat into a universal grinder and grind it thoroughly to make it into uniform and fine meat mince. Then, prepare the liquid with a ratio of 1:2 between water and meat mince to prepare for the subsequent enzymatic hydrolysis process.

[0070] S3: Enzymatic hydrolysis

[0071] Add an appropriate amount of enzyme to the prepared liquid, and strictly control the temperature and time during the enzymolysis process. Set the enzymolysis temperature to 48°C and perform the enzymolysis reaction at this temperature for 3.5 hours. The amount of enzyme added for enzymolysis is controlled to 0.5% to ensure that the enzymolysis reaction can be carried out efficiently and fully, thereby obtaining high-quality enzymolysis solution.

[0072] S4: Centrifugation

[0073] Transfer the enzymatic hydrolysate to a centrifuge, set the speed of the centrifuge to 10,000 r / min, and centrifuge for 4.5 minutes. Through centrifugation, the solid and liquid in the enzymatic hydrolysate are effectively separated, providing a pure supernatant for the subsequent concentration process.

[0074] S5: Condensation

[0075] The supernatant produced by the centrifuge is concentrated by a professional concentrator. The temperature of the concentrator is set at 50°C, the pressure is maintained at -0.1Mpa, and the condensation temperature is controlled at 10°C. Under such conditions, the water in the supernatant is gradually removed to achieve the concentration effect.

[0076] S6: Spray Drying

[0077] The concentrated supernatant material is atomized and then sent to the drying chamber. When the material is fully in contact with the hot air, the water vaporizes rapidly. At this time, the material content is strictly controlled to be 8%, the inlet temperature of the drying chamber is 110°C, and the outlet temperature is 78°C, and finally the dried giant salamander polypeptide powder is obtained.

[0078] Embodiment 2

[0079] The components of the formula of the giant salamander polypeptide powder composition for immunomodulation are as follows by weight:

[0080] 15 servings of Giant Salamander Peptide Powder: The proportion of Giant Salamander Peptide Powder is further increased to strengthen its core role in immune regulation.

[0081] 35 servings of oyster peptides: Rationally adjust the dosage of oyster peptides to better cooperate with other ingredients to exert their immune-regulating effects.

[0082] 20 servings of soybean peptides: An appropriate amount of soybean peptides helps improve the body's absorption and utilization of nutrients and promotes the activity of immune cells.

[0083] 10 parts of Chinese yam powder: The addition of Chinese yam powder provides the composition with richer nutritional and nourishing ingredients, and enhances the mild conditioning effect on the body.

[0084] 10 servings of Apple Powder: The steady addition of apple powder helps maintain intestinal health and creates a good internal environment for immune regulation.

[0085] 10 servings of wolfberry powder: The increased content of wolfberry powder makes its effects in regulating immune function and anti-oxidation more significant.

[0086] 10 parts of seabuckthorn fruit powder: The reasonable proportion of seabuckthorn fruit powder enhances the biological activity of the composition and improves the overall immune regulation ability.

[0087] 30 servings of oligofructose: The appropriate amount of oligofructose helps to further optimize the intestinal flora and enhance the intestinal immune barrier.

[0088] 10 servings of water-soluble dietary fiber: maintains normal intestinal function, promotes intestinal peristalsis, and plays a positive auxiliary role in immune regulation.

[0089] 5 parts of stevioside: adjusts the taste so that the composition has better palatability while ensuring the efficacy.

[0090] Preparation technology of giant salamander polypeptide powder

[0091] S1: Preprocessing

[0092] Similarly, healthy giant salamanders are selected and the mucus is removed, blood is drained, blood is collected and frozen according to standard procedures. The giant salamander meat is removed and the head, tail and limbs are frozen for later use.

[0093] S2: Smash

[0094] The pre-processed giant salamander meat is crushed into minced meat, and the liquid is prepared according to the ratio of water to minced meat of 1:3.5.

[0095] S3: Enzymatic hydrolysis

[0096] Enzymes were added to the liquid, the enzymolysis temperature was controlled at 52°C, the enzymolysis time was 4 hours, and the enzyme addition amount was 0.8% to ensure the best enzymolysis effect.

[0097] S4: Centrifugation

[0098] The enzymatic hydrolysate was placed in a centrifuge and centrifuged at 13000 r / min for 6 minutes to achieve solid-liquid separation.

[0099] S5: Condensation

[0100] The supernatant was concentrated by a concentrator with the temperature of the concentrator set at 52°C, the pressure at -0.1 MPa, and the condensation temperature at 10.5°C.

[0101] S6: Spray Drying

[0102] The concentrated material is atomized and sent to a drying chamber, the material content is 13%, the inlet temperature of the drying chamber is 110° C., and the outlet temperature is 85° C., to obtain dry giant salamander polypeptide powder.

[0103] Embodiment 3

[0104] The components of the formula of the giant salamander polypeptide powder composition for immunomodulation are as follows by weight:

[0105] 18 portions of giant salamander polypeptide powder: The higher proportion of giant salamander polypeptide powder further highlights its important role in immune regulation.

[0106] 39 portions of oyster polypeptide: Increasing the dosage of oyster polypeptide enhances the immunomodulatory effect of the composition.

[0107] 24 servings of soy peptides: Rich soy peptides provide the body with more high-quality nutrients and help improve the activity and function of immune cells.

[0108] 12 servings of yam powder: The addition of yam powder further enhances the nourishing effect on the body and promotes overall health.

[0109] 13 servings of apple powder: More apple powder helps maintain intestinal health and promotes the absorption and utilization of nutrients.

[0110] 14.5 portions of wolfberry powder: wolfberry powder with a higher content has a more powerful effect in regulating immune function and anti-oxidation.

[0111] 12 parts of seabuckthorn fruit powder: The addition of seabuckthorn fruit powder enhances the biological activity and immunomodulatory ability of the composition.

[0112] 33 servings of oligofructose: Increasing the amount of oligofructose can help optimize the intestinal microecological environment and enhance intestinal immune function.

[0113] 12 servings of water-soluble dietary fiber: maintains normal physiological function of the intestines and plays an important supporting role in immune regulation.

[0114] 7 parts of stevioside: adjusts the taste and makes the composition more acceptable to consumers.

[0115] Preparation technology of giant salamander polypeptide powder

[0116] S1: Preprocessing

[0117] Healthy giant salamanders are pre-processed by removing mucus, bleeding, collecting blood for freezing, taking meat, and freezing the head, tail and limbs for later use.

[0118] S2: Smash

[0119] The pre-treated giant salamander meat is crushed into minced meat, and a feed liquid is prepared according to a ratio of 1:4 between water and minced meat.

[0120] S3: Enzymatic hydrolysis

[0121] Enzyme was added to the liquid, the enzymolysis temperature was 58°C, the enzymolysis time was 2-8 hours, and the enzyme addition amount was 1%, to ensure that the enzymolysis reaction was fully carried out.

[0122] S4: Centrifugation

[0123] The enzymatic hydrolysate was placed in a centrifuge and centrifuged at 18000 r / min for 7 minutes to achieve solid-liquid separation.

[0124] S5: Condensation

[0125] The supernatant was concentrated by a concentrator with the temperature of the concentrator set at 54°C, the pressure at -0.1 MPa, and the condensation temperature at 11°C.

[0126] S6: Spray Drying

[0127] The concentrated material is atomized and sent to a drying chamber, the material content is 15%, the inlet temperature of the drying chamber is 120°C, and the outlet temperature is 92°C, to obtain dry giant salamander polypeptide powder.

[0128] In summary, the giant salamander polypeptide powder composition for immunomodulation involved in the present invention has many significant advantages. The giant salamander polypeptide small molecule peptide in the composition accounts for a high proportion, and contains metallothionein (MT), which has the effect of heavy metal detoxification and anti-aging. The composition ratio of giant salamander protein and amino acid is basically the same as that of humans and is easily absorbed by the human body. The ingredients such as arginine, glutamine and leucine can effectively enhance the patient's immune function and reduce the incidence of postoperative infection. In addition, the composition also contains DHA and phosphatidylserine, which is particularly suitable for people who need to quickly recover their physical fitness after surgery, sub-healthy groups, people with cardiovascular and cerebrovascular diseases, and people with low immunity under high-pressure working environments. At the same time, the composition can also prevent Alzheimer's disease and memory degeneration, significantly improve the immune regulation ability of the human body, and provide a strong guarantee for the health of different groups of people.

[0129] The above shows and describes the basic principles, main features and advantages of the present invention. It should be understood by those skilled in the art that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A formula of a giant salamander polypeptide powder composition for immunomodulation, characterized in that: Contains the following components by weight: 10-20 parts of giant salamander polypeptide powder, which is prepared by a specific process and is rich in a variety of bioactive peptides and has significant immunomodulatory potential; 30-40 servings of oyster peptides, which are extracted from high-quality oysters and contain a variety of amino acids and functional ingredients, which help enhance immune regulation. 15-25 parts of soybean peptides. Soy peptides are derived from the hydrolysis of soybean protein. They are easy to absorb and have high biological activity, and play a synergistic role in overall immune regulation. 5-15 portions of yam powder. The yam powder is finely ground to retain a variety of nutrients in the yam, providing gentle nourishment for immune regulation; 6-14 servings of apple powder. Apple powder is made from high-quality apples and is rich in vitamins, minerals, pectin, etc., which can help improve the body's immune vitality; 4-16 servings of wolfberry powder. Wolfberry powder is processed from natural wolfberries. The wolfberry polysaccharides it contains play a positive role in immune regulation. 5-14 parts of seabuckthorn fruit powder. Seabuckthorn fruit powder is extracted from seabuckthorn fruit and is rich in various bioactive substances, which can enhance the immune regulation effect; 22-36 parts of oligofructose. As a prebiotic, oligofructose can regulate intestinal flora and indirectly promote the body's immune regulation function; 5-13 servings of water-soluble dietary fiber, which helps maintain intestinal health and intestinal barrier function, thus having a positive impact on immune regulation; 1-8 parts of stevioside are used to adjust the taste and improve the palatability of the product without adding too much calories.

2. A preparation process of a composition formula of giant salamander polypeptide powder for immunomodulation, characterized in that: It is used to prepare a giant salamander polypeptide powder composition formula for immune regulation as described in claim 1, and the preparation process comprises the following steps: S1: Pretreatment: Select healthy giant salamanders, first use a specific cleaning method to remove the mucus on their body surface, then use precise cutting techniques to cut open the neck of the giant salamander to bleed, collect the blood and freeze it, then remove the giant salamander meat, and properly freeze the head, tail and limbs for later use; S2: Grinding: Put the pre-treated giant salamander meat into a universal grinder, grind it into uniform meat pieces, and prepare it into liquid according to a specific ratio to ensure the smooth progress of the subsequent enzymatic hydrolysis process; S3: Enzyme hydrolysis: Add enzymes of specific types and proportions to the feed solution, perform enzymolysis reaction at a temperature range of 45-60°C for 2-8 hours, and obtain high-quality enzymolysis solution after the enzymolysis is completed; S4: Centrifugation: Place the enzymatic hydrolysate into a centrifuge, set the speed to 4000-20000 r / min, and perform centrifugation for 3-10 minutes to achieve solid-liquid separation; S5: Concentration: The supernatant produced by the centrifuge is concentrated by a professional concentrator. The temperature of the concentrator is set at 50-55°C, the pressure is maintained at -0.1Mpa, and the condensation temperature is controlled at 10-11°C; S6: Spray drying: The concentrated supernatant material is atomized and sent to a drying chamber. During the process of full contact with hot air, the water vaporizes rapidly, and finally dry giant salamander polypeptide powder is obtained.

3. The preparation process of a giant salamander polypeptide powder composition for immunomodulation according to claim 2, characterized in that: In the S1 step, the bloodletting operation uses professional tools and processes to ensure that the blood is collected completely, and the freezing temperature of the collected blood is controlled below -18°C to maintain the stability of the bioactive substances in the blood.

4. The preparation process of a giant salamander polypeptide powder composition for immunomodulation according to claim 2, characterized in that: The ratio of the liquid, water and minced meat in step S3 is strictly controlled at 1:1-6, and the amount of enzyme added during the enzymatic hydrolysis is precisely controlled at 0.3-1.2%, so as to ensure that the enzymatic hydrolysis reaction is efficient and sufficient.

5. The preparation process of a composition formula of giant salamander polypeptide powder for immunomodulation according to claim 2, characterized in that: In step S6, the content of the material entering the spray drying process is stabilized at 5-20%, the inlet temperature of the drying chamber is maintained at 120-170° C., and the outlet temperature is maintained at 70-95° C., ensuring the quality and activity of the giant salamander polypeptide powder.