Bone marrow sample collecting device

Abstract

The invention relates to a bone marrow sample collecting device which comprises a connecting base, a sampling structure is arranged on the connecting base, the sampling structure comprises a needle cylinder and a sampling needle, the needle cylinder is fixedly connected to the connecting base, the sampling needle is slidably connected into the needle cylinder, four liquid inlets are formed in the positions, close to the bottom end, of the sampling needle, and the liquid inlets are communicated with the sampling needle. Four liquid outlets are formed in the position, close to the top end, of the sampling needle, a connecting sleeve is fixedly connected to the position, close to the top end, of the outer side of the sampling needle, four sliding rods are fixedly connected to the bottom end of the connecting sleeve, the sliding rods are slidably connected to a connecting base, a limiting structure is arranged on the connecting base, and a sealing structure is arranged on the sampling needle. The sampling device has the advantages that the sampling operation time can be shortened, the sampling operation convenience is improved, and meanwhile quantitative samples can be accurately and stably extracted.

Description

Technical Field

[0001] The present application relates to the technical field of sampling devices, and in particular to a bone marrow sample collection device. Background Art

[0002] Bone marrow transplantation is usually carried out according to the steps of bone marrow matching, pretreatment, bone marrow sampling, transplantation, and postoperative treatment. During bone marrow sampling, anesthetics are first injected locally, and then bone marrow is extracted from the donor's iliac bone using a sampling device. Finally, the stem cell-rich bone marrow is stored to facilitate subsequent bone marrow transplantation surgery.

[0003] However, a general sampling device includes a needle core and a needle sheath. Since the front end of the needle core is relatively sharp, it is convenient to pierce the patient's body. When the specified position is reached, the needle core needs to be pulled out of the needle sheath, and then the front end of the syringe is connected to the rear end of the needle sheath, and the sampling is achieved by pulling the syringe. This process is relatively time-consuming, and it is not convenient for rapid sampling. In addition, the end of the syringe is generally threadedly connected to the needle sheath, so each sampling requires a certain amount of time to twist the syringe, which is not convenient for rapid disassembly and assembly of the syringe. When sampling through the syringe, the doctor needs to pull the syringe by hand. When the pulling force is large, it is easy to pull the needle sheath, thereby causing the position of the needle sheath to change. At the same time, when the pulling force is large, more samples will be extracted at one time, which is not convenient for accurate and stable extraction of quantitative samples. Summary of the invention

[0004] In order to shorten the sampling operation time, improve the convenience of sampling operation, and realize accurate and stable extraction of quantitative samples, the present application provides a bone marrow sample collection device.

[0005] The present application provides a bone marrow sample collection device, which adopts the following technical solution: A bone marrow sample collection device comprises a connecting seat, a sampling structure is provided on the connecting seat, the sampling structure comprises a syringe and a sampling needle, the connecting seat is fixedly connected to the syringe, the sampling needle is slidably connected to the inside of the syringe, the sampling needle is provided with four liquid inlets near the bottom end, the sampling needle is provided with four liquid outlets near the top end, a connecting sleeve is fixedly connected to the outer side of the sampling needle near the top end, four sliding rods are fixedly connected to the bottom end of the connecting sleeve, the sliding rods are slidably connected to the connecting seat, a limiting structure is provided on the connecting seat, a sealing structure is provided on the sampling needle, and a collecting structure is provided on the top end of the sampling needle.

[0006] By adopting the above technical solution, the limiting structure will limit the sliding rod again, so that the sampling needle cannot move. Then, under the action of the collecting structure, the sample liquid will enter the interior of the sampling needle from the four liquid inlets, and finally flow out from the four liquid outlets, and finally enter the interior of the collecting structure for collection, thereby realizing rapid sampling, shortening the sampling time, and improving the convenience of the sampling operation.

[0007] Optionally, the cross-section of the bottom end of the sampling needle is a conical structure, and a handle is fixedly connected to the connecting seat.

[0008] By adopting the above technical solution, the doctor can better apply pressure by holding the handle, so that the sampling needle can be inserted into the patient's body.

[0009] Optionally, the limiting structure includes a sliding sleeve and a resist sleeve, the sliding sleeve is slidably connected to the connecting seat, the top of the sliding sleeve is fixedly connected to the bottom ends of the three sliding rods, the inside of the sliding sleeve is slidably connected to the resist sleeve, a first spring is in contact with the resist sleeve and the sliding sleeve, the sliding sleeve is movably connected to a plurality of limiting beads inside, three limiting grooves are provided on the connecting seat, a plurality of the limiting beads are located inside one of the limiting grooves, and a groove is provided on the inner side of the resist sleeve.

[0010] By adopting the above technical solution, the three sliding bars slide on the connecting seat to prevent the connecting sleeve from rotating. The movement of the three sliding bars will drive the connecting sleeve to move, and the movement of the connecting sleeve will drive the sampling needle to move. When the liquid inlet moves from the inside of the syringe to the outside of the syringe, the first spring will extend and drive the sleeve to move. The sleeve will interfere with the engagement between multiple limit beads and another limit groove. At this time, the sliding sleeve will be unable to continue moving, thereby achieving the fixation of the sampling needle after the position is adjusted.

[0011] Optionally, the bottom end of the abutment sleeve extends to the outside of the sliding sleeve, and four limiting beads are provided, and the four limiting beads are distributed in a circular array about the middle of the sliding sleeve.

[0012] By adopting the above technical solution, since the bottom end of the sleeve extends to the outside of the sliding sleeve, it is convenient to press the sleeve, and the stability during limiting can be improved by providing four limiting beads.

[0013] Optionally, the sealing structure includes a sealing sleeve and a second spring, the sealing sleeve is slidably connected to the outer side of the sampling needle near the top, and the second spring is fixedly connected between the sealing sleeve and the connecting sleeve.

[0014] By adopting the above technical solution, during the process of pulling out the collecting tube, the second spring will extend and drive the sealing sleeve to slide on the sampling needle. As the collecting tube is pulled out, the sealing sleeve will seal multiple liquid outlets, thereby preventing the sample liquid from overflowing from the liquid outlet after the collecting tube is pulled out, making it more convenient to use.

[0015] Optionally, the collecting structure includes a collecting cylinder and an end cover, the sealing sleeve is in contact with the bottom end of the collecting cylinder, the top end of the collecting cylinder is threadedly connected to the end cover, the end cover is threadedly connected to a screw, the bottom end of the screw is rotatably connected to a piston, the piston is slidably connected to the collecting cylinder, and the top end of the screw is fixedly connected to a crank.

[0016] By adopting the above technical solution, as the screw rotates, the piston will slide inside the collecting tube, thereby generating negative pressure inside the collecting tube. Under the action of the negative pressure, the sample liquid will enter the interior of the collecting tube for collection. Driving the piston movement by the screw can save effort and can accurately and stably control the movement distance of the piston, thereby facilitating the accurate and stable extraction of a certain amount of sample liquid.

[0017] Optionally, scale lines are provided on the outer side of the collecting tube, and the collecting tube is made of a transparent material.

[0018] By adopting the above technical solution, since the collecting tube is made of transparent material, the volume of the sample liquid collected inside the collecting tube can be easily observed, and the specific volume of the extracted sample liquid can be known through the scale line, which also makes it convenient to stop extracting the sample liquid in time after a certain amount of sample liquid is extracted.

[0019] Optionally, a fixing structure is provided on the connecting sleeve, and the fixing structure includes a pressing plate and a slider. Two sliders are slidably connected to the connecting sleeve, and one end of the slider close to the collecting tube is rotatably connected to two connecting rods. The bottom end of the collecting tube is fixedly connected to a limiting sleeve, and two blocks are clamped on the outer side of the limiting sleeve, and both ends of the blocks are rotatably connected to two adjacent connecting rods.

[0020] By adopting the above technical solution, the simultaneous movement of the four connecting rods will cause the two blocks to move away from the limit sleeve. When the two blocks are not engaged with the limit sleeve, the collecting tube can be moved and taken out from the inside of the sealing sleeve, thereby realizing the rapid separation of the collecting tube and the sealing sleeve, shortening the operation time and improving the sampling efficiency.

[0021] Optionally, a pressing plate is fixedly connected to one end of the sliding block facing away from the collecting cylinder, and a cross section between the pressing plate and the sliding block is in a T-shaped structure.

[0022] By adopting the above technical solution, since the contact area between the pressing sheet and the finger is larger, the movement of the slider by pressing the pressing sheet can be more comfortable.

[0023] Optionally, a third spring is provided on the outer sleeve of the sliding block, one end of the third spring abuts against the pressing sheet, and the other end of the third spring abuts against the connecting sleeve.

[0024] By adopting the above technical solution, after the limiting sleeve reaches the specified position, the clamping block can be automatically engaged with the limiting sleeve under the action of the third spring, thereby improving the convenience of operation.

[0025] In summary, the present application includes at least one of the following beneficial technical effects: 1. When sampling, the position of the syringe can be moved by pressing the sleeve and the sliding sleeve. When the syringe moves a specified distance, the limit bead will automatically engage with the limit groove under the action of the first spring. At this time, the syringe cannot move, and then sampling can be performed directly by turning the crank, thereby simplifying the sampling steps, effectively shortening the sampling time, and improving the convenience of the sampling operation; 2. When sampling, the piston can move inside the collection tube to generate negative pressure. Under the action of negative pressure, the sample liquid will enter the collection tube for collection. The movement of the piston driven by the screw can save more effort and can accurately and stably control the movement distance of the piston, so as to facilitate accurate and stable extraction of quantitative sample liquid; 3. After the sample liquid is extracted, the two clamping blocks can be moved away from the limiting sleeve by pressing the two pressing pieces at the same time. When the two clamping blocks are not engaged with the limiting sleeve, the collecting tube can be moved and taken out from the inside of the sealing sleeve, thereby realizing the rapid separation of the collecting tube and the sealing sleeve, shortening the operation time and improving the sampling efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figure 1 It is a schematic diagram of the overall structure of the present invention; Figure 2 It is a schematic diagram of the connection structure between the screw and the piston of the present invention; Figure 3 for Figure 2 An enlarged schematic diagram of part A is shown; Figure 4 for Figure 2 An enlarged schematic diagram of part B is shown; Figure 5 for Figure 2 An enlarged schematic diagram of part C is shown; Figure 6 It is a schematic diagram of the connection structure between the sliding sleeve and the limiting bead of the present invention; Figure 7 It is a schematic diagram of the connection structure between the connection base and the handle of the present invention; Figure 8 It is a schematic diagram of the connection structure between the syringe and the liquid outlet of the present invention.

[0027] 1. Connecting seat; 2. Sampling structure; 201. Syringe; 202. Sampling needle; 203. Liquid inlet; 204. Liquid outlet; 205. Connecting sleeve; 206. Sliding rod; 3. Limiting structure; 301. Sliding sleeve; 302. Abutting sleeve; 303. First spring; 304. Limiting bead; 305. Limiting groove; 306. Groove; 4. Sealing structure; 401. Sealing sleeve; 402. Second spring; 5. Fixing structure; 501. Pressing sheet; 502. Sliding block; 503. Third spring; 504. Connecting rod; 505. Block; 506. Limiting sleeve; 6. Collecting structure; 601. Collecting cylinder; 602. End cover; 603. Crank handle; 604. Screw; 605. Piston; 606. Scale line; 7. Handle. DETAILED DESCRIPTION

[0028] The present invention is further described in detail below in conjunction with the accompanying drawings and embodiments, wherein the same components are represented by the same reference numerals.

[0029] Reference Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 , Figure 7 and Figure 8 A bone marrow sample collection device comprises a connecting seat 1, a sampling structure 2 is provided on the connecting seat 1, a limiting structure 3 is provided on the connecting seat 1, a sealing structure 4 is provided on the sampling needle 202, and a collecting structure 6 is provided at the top of the sampling needle 202.

[0030] When the liquid inlet 203 moves from the inside of the syringe 201 to the outside of the syringe 201, the first spring 303 will stretch to drive the sleeve 302 to move, and the sleeve 302 will interfere with the plurality of limiting beads 304 and engage with another limiting groove 305. At this time, the sleeve 301 will not be able to continue moving, thereby achieving the fixation of the sampling needle 202 after the position adjustment, and the piston 605 slides inside the collecting tube 601, thereby generating negative pressure inside the collecting tube 601, and then the sample liquid will enter the sampling needle 202 from the four liquid inlets 203, and finally flow out from the four liquid outlets 204, and finally enter the collecting tube 601 for collection, thereby achieving rapid sampling, shortening the sampling time, and improving the convenience of the sampling operation.

[0031] Reference Figure 3 A sealing sleeve 401 is slidably connected to the outer side of the sampling needle 202 near the top, and a second spring 402 is fixedly connected between the sealing sleeve 401 and the connecting sleeve 205 .

[0032] As the collecting tube 601 is pulled out, the sealing sleeve 401 will seal the multiple liquid outlets 204, thereby preventing the sample liquid from overflowing from the liquid outlet 204 after the collecting tube 601 is pulled out, making it more convenient to use. As the sealing sleeve 401 continues to move, the blocking block 505 will engage with the limiting sleeve 506. At this time, the sealing sleeve 401 will not block the multiple liquid outlets 204, thereby facilitating the sample liquid to enter the interior of the collecting tube 601 from the multiple liquid outlets 204.

[0033] Reference Figure 1 , Figure 2 and Figure 3 The bottom end of the screw rod 604 is rotatably connected to a piston 605, and the piston 605 is slidably connected to the collecting tube 601. The top end of the screw rod 604 is fixedly connected to a crank 603. A scale line 606 is provided on the outside of the collecting tube 601, and the collecting tube 601 is made of a transparent material.

[0034] Driving the piston 605 to move through the screw 604 can save more effort and can accurately and stably control the movement distance of the piston 605, thereby facilitating the accurate and stable extraction of a quantitative sample liquid. The interior of the collection tube 601 can be cleaned by twisting off the end cap 602 from the end of the collection tube 601, making it easier to use.

[0035] Reference Figure 2 and Figure 3 Two sliders 502 are slidably connected to the connecting sleeve 205, and one end of the slider 502 close to the collecting tube 601 is rotatably connected to two connecting rods 504. The bottom end of the collecting tube 601 is fixedly connected to a limiting sleeve 506, and two clamping blocks 505 are clamped on the outer side of the limiting sleeve 506. The two ends of the clamping blocks 505 are respectively rotatably connected to two adjacent connecting rods 504. The end of the slider 502 facing away from the collecting tube 601 is fixedly connected to a pressing plate 501, and the outer sleeve of the slider 502 is provided with a third spring 503, one end of the third spring 503 abuts against the pressing plate 501, and the other end of the third spring 503 abuts against the connecting sleeve 205.

[0036] When the sample liquid is extracted, the two pressing pieces 501 can be pressed at the same time, and the third spring 503 will shrink. Since the contact area between the pressing piece 501 and the finger is large, the comfort during pressing can be improved. When the two blocking blocks 505 are not engaged with the limiting sleeve 506, the collecting tube 601 can be moved and taken out from the inside of the sealing sleeve 401, thereby realizing the rapid separation of the collecting tube 601 and the sealing sleeve 401, shortening the operation time and improving the sampling efficiency.

[0037] The embodiment of the present application discloses a bone marrow sample collection device having the following implementation principles: during use, the handle 7 can be held to insert the syringe 201 into the patient's body. Since the front end of the sampling needle 202 is relatively sharp, it is convenient for it to be inserted into the patient's body. When the end of the sampling needle 202 is located at the sampling site, the sleeve 302 can be pressed to contract the first spring 303. During the movement of the sleeve 302, the groove 306 will be driven to move toward the plurality of limiting beads 304. When the top of the sleeve 302 contacts the sliding sleeve 301, the sleeve 302 cannot be pushed further. At this time, the plurality of limiting beads 304 are located on one side of the groove 306, and then the sliding sleeve can be pushed. 301, at this time, the limiting bead 304 will move toward the inside of the groove 306, so that the sliding sleeve 301 can move smoothly on the connecting seat 1, the movement of the sliding sleeve 301 will drive the three sliding rods 206 to move, and the three sliding rods 206 can slide on the connecting seat 1 to prevent the connecting sleeve 205 from rotating, and the movement of the three sliding rods 206 will drive the connecting sleeve 205 to move, and the movement of the connecting sleeve 205 will drive the sampling needle 202 to move. When the liquid inlet 203 moves from the inside of the syringe 201 to the outside of the syringe 201, the first spring 303 will extend and drive the sleeve 302 to move, and the sleeve 302 will interfere with the engagement between the plurality of limiting beads 304 and another limiting groove 305. At this time, the sliding sleeve 301 will not be able to continue to move, thereby achieving the fixation of the sampling needle 202 after the position adjustment, and then hold the collecting tube 601 with one hand and hold the crank 603 with the other hand, and then turn the crank 603, the rotation of the crank 603 will drive the screw 604 to rotate, because the screw 604 and the end cover 602 are threadedly connected, and are also rotationally connected to the piston 605. Therefore, as the screw 604 rotates, the piston 605 will slide inside the collecting tube 601, so that negative pressure will be generated inside the collecting tube 601. Under the action of the negative pressure, the sample liquid will enter the interior of the sampling needle 202 from the four liquid inlets 203, and finally flow out from the four liquid outlets 204. The sample is then drawn out and finally enters the interior of the collection barrel 601 for collection. When the sampling device is not needed, the front end of the sampling needle 202 can be moved to the interior of the syringe 201, thereby preventing the front end from being damaged, thereby effectively improving the safety of use. Since the collection barrel 601 is made of a transparent material, the volume of the sample liquid collected in the collection barrel 601 can be conveniently observed, and the specific volume of the sample liquid extracted can be known through the scale line 606, which is also convenient for stopping the extraction of the sample liquid in time after a certain amount of sample liquid is extracted. The movement of the piston 605 driven by the screw 604 can save more effort, and the movement distance of the piston 605 can be accurately and stably controlled. When the sample liquid is extracted, the two pressing pieces 501 can be pressed at the same time, and the third spring 503 will contract. The movement of the pressing piece 501 will drive the slider 502 to move, and the movement of the slider 502 will drive the two connecting rods 504 to move. The simultaneous movement of the four connecting rods 504 will cause the two clamping blocks 505 to move away from the limiting sleeve 506. When the two clamping blocks 505 are not engaged with the limiting sleeve 506, the collecting cylinder 601 can be moved and taken out from the inside of the sealing sleeve 401. In the process of pulling out the collecting cylinder 601, the second spring 402 will extend to drive the sealing sleeve 401 to slide on the sampling needle 202. As the collecting cylinder 601 is pulled out, the sealing sleeve 401 will The liquid outlets 204 are sealed, thereby preventing the sample liquid from overflowing from the liquid outlet 204 after the collecting tube 601 is pulled out. During the insertion of the collecting tube 601, it will resist the sealing sleeve 401 and slide on the sampling needle 202. As the sealing sleeve 401 continues to move, the block 505 will engage with the limiting sleeve 506. At this time, the sealing sleeve 401 will not block the multiple liquid outlets 204, thereby facilitating the sample liquid to enter the interior of the collecting tube 601 from the multiple liquid outlets 204. At the same time, under the action of the second spring 402, the sealing sleeve 401 and the collecting tube 601 can be tightly pressed against each other, thereby improving the sealing between the sealing sleeve 401 and the collecting tube 601.

[0038] The above is only a preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above embodiments. All technical solutions under the concept of the present invention belong to the protection scope of the present invention. It should be pointed out that for ordinary technicians in this technical field, some improvements and modifications without departing from the principle of the present invention should also be regarded as the protection scope of the present invention.

Claims

1. A bone marrow sample collection device, comprising a connection seat (1), characterized in that: The connection seat (1) is provided with a sampling structure (2), the sampling structure (2) comprising a syringe (201) and a sampling needle (202), the connection seat (1) is fixedly connected with the syringe (201), the sampling needle (202) is slidably connected inside the syringe (201), the sampling needle (202) is provided with four liquid inlets (203) near the bottom end of the sampling needle (202), the sampling needle (202) is provided with four liquid outlets (204) near the top end, the outer side of the sampling needle (202) is fixedly connected with a connecting sleeve (205) near the top end, the bottom end of the connecting sleeve (205) is fixedly connected with four sliding rods (206), the sliding rods (206) are slidably connected to the connection seat (1), the connection seat (1) is provided with a limiting structure (3), the sampling needle (202) is provided with a sealing structure (4), and the top end of the sampling needle (202) is provided with a collecting structure (6).

2. A bone marrow sample collection device according to claim 1, characterized in that: The cross-section of the bottom end of the sampling needle (202) is a conical structure, and a handle (7) is fixedly connected to the connecting seat (1).

3. A bone marrow sample collection device according to claim 1, characterized in that: The limiting structure (3) comprises a sliding sleeve (301) and a resisting sleeve (302); the connecting seat (1) is slidably connected with the sliding sleeve (301); the top of the sliding sleeve (301) is fixedly connected to the bottom ends of the three sliding rods (206); the inside of the sliding sleeve (301) is slidably connected with the resisting sleeve (302); a first spring (303) is abutted between the resisting sleeve (302) and the sliding sleeve (301); a plurality of limiting beads (304) are movably connected inside the sliding sleeve (301); three limiting grooves (305) are provided on the connecting seat (1); a plurality of limiting beads (304) are located inside one of the limiting grooves (305); and a groove (306) is provided on the inner side of the resisting sleeve (302).

4. A bone marrow sample collection device according to claim 3, characterized in that: The bottom end of the abutment sleeve (302) extends to the outside of the sliding sleeve (301), and four limiting beads (304) are provided. The four limiting beads (304) are distributed in a circular array about the middle of the sliding sleeve (301).

5. A bone marrow sample collection device according to claim 1, characterized in that: The sealing structure (4) comprises a sealing sleeve (401) and a second spring (402); the sealing sleeve (401) is slidably connected to the outside of the sampling needle (202) near the top end; and the second spring (402) is fixedly connected between the sealing sleeve (401) and the connecting sleeve (205).

6. A bone marrow sample collection device according to claim 5, characterized in that: The collecting structure (6) comprises a collecting tube (601) and an end cover (602), the sealing sleeve (401) abuts against the bottom end of the collecting tube (601), the top end of the collecting tube (601) is threadedly connected to the end cover (602), the end cover (602) is threadedly connected to a screw rod (604), the bottom end of the screw rod (604) is rotatably connected to a piston (605), the piston (605) is slidably connected to the collecting tube (601), and the top end of the screw rod (604) is fixedly connected to a crank (603).

7. A bone marrow sample collection device according to claim 6, characterized in that: The outer side of the collecting tube (601) is provided with scale lines (606), and the collecting tube (601) is made of a transparent material.

8. A bone marrow sample collection device according to claim 6, characterized in that: The connecting sleeve (205) is provided with a fixing structure (5), the fixing structure (5) comprising a pressing sheet (501) and a slider (502), the connecting sleeve (205) being slidably connected to two sliders (502), one end of the slider (502) close to the collecting barrel (601) being rotatably connected to two connecting rods (504), the bottom end of the collecting barrel (601) being fixedly connected to a limiting sleeve (506), the outer side of the limiting sleeve (506) being clamped with two clamping blocks (505), and the two ends of the clamping blocks (505) being rotatably connected to two adjacent connecting rods (504) respectively.

9. A bone marrow sample collection device according to claim 8, characterized in that: One end of the sliding block (502) facing away from the collecting cylinder (601) is fixedly connected to a pressing plate (501), and the cross section between the pressing plate (501) and the sliding block (502) is in a T-shaped structure.

10. A bone marrow sample collection device according to claim 9, characterized in that: The outer sleeve of the sliding block (502) is provided with a third spring (503), one end of the third spring (503) abuts against the pressing sheet (501), and the other end of the third spring (503) abuts against the connecting sleeve (205).

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