Nerve stimulation method and device

Abstract

The embodiment of the invention provides a nerve stimulation method and device, and the method comprises the steps: starting a nerve stimulation instrument, selecting a working mode, and controlling the nerve stimulation instrument to carry out the nerve stimulation of a target head according to a treatment parameter preset by a doctor under the condition of selecting a doctor mode; under the condition that the user mode is selected, the nerve stimulation instrument is controlled to conduct nerve stimulation on the target head according to the treatment parameters set by the user, specific requirements of different patients can be flexibly met, and the treatment effectiveness is fully exerted.

Description

Technical Field

[0001] The present invention relates to the medical field, and in particular to a nerve stimulation method and a device thereof. Background Art

[0002] Transcranial nerve stimulation is a treatment method that modulates the nervous system in the head through external or internal devices. This technology can be used to treat a variety of neurological diseases and symptoms, such as chronic pain, Parkinson's disease, depression, epilepsy, anxiety, etc.

[0003] Traditional neurostimulators usually use fixed treatment parameters, which are often designed based on the average data of the general population and lack the ability to adjust them for different users. Since each user's physiological state, severity of the disease, tolerance, and sensitivity to stimulation are different, fixed parameter settings may not meet individualized treatment needs. For example, for some users, the preset stimulation intensity may be too high, causing discomfort or even side effects; while for other users, the same intensity may be too low to achieve the expected treatment effect. This "one-size-fits-all" design not only limits the effectiveness of treatment, but may also reduce user compliance and satisfaction. In addition, fixed parameters cannot be dynamically adjusted based on the user's real-time feedback or changes in the disease, further affecting the accuracy and long-term effects of the treatment. Therefore, traditional neurostimulators have obvious deficiencies in meeting personalized treatment needs, and there is an urgent need for a solution that can flexibly adjust parameters to adapt to the specific needs of different users. Summary of the invention

[0004] In view of the above problems, a method and device for nerve stimulation are proposed to overcome the above problems or at least partially solve the above problems, including: A method of neural stimulation, the method comprising: Start the nerve stimulation instrument and select the working mode, which includes doctor mode and user mode; When the doctor mode is selected, the neurostimulator is controlled to perform neurostimulation on the target head according to the treatment parameters preset by the doctor; When the user mode is selected, the neurostimulation device is controlled to perform neurostimulation on the target head according to the treatment parameters set by the user.

[0005] Optionally, when the doctor mode is selected, the neurostimulator is controlled to perform neurostimulation on the target head according to the treatment parameters preset by the doctor, including: In the case of selecting the doctor mode, a user account is logged in on the neurostimulator, the user account corresponds to the treatment parameters pre-set by the doctor, and the neurostimulator is controlled to perform neurostimulation on the target head according to the treatment parameters pre-set by the doctor until the preset stimulation time is reached; Among them, the treatment parameters pre-set by the doctor are fixed values.

[0006] Optionally, when the user mode is selected, the neurostimulator is controlled to perform neurostimulation on the target head according to the treatment parameters set by the user, including: When the user mode is selected, the neurostimulation mode is selected on the neurostimulation instrument according to the target disease and the treatment parameters are set. The neurostimulation instrument is controlled to perform neurostimulation on the target head according to the treatment parameters set by the user until the preset stimulation time is reached.

[0007] Optionally, nerve stimulation is performed on the target head until a preset stimulation time is reached, including: When all treatment parameters are less than the safety value, the nerve stimulation device is controlled to perform nerve stimulation on the target head until the preset stimulation time is reached; When at least one of the treatment parameters is greater than or equal to the safety value, the neurostimulator is controlled to stop neurostimulation on the target head, an abnormal alarm is issued, and the EEG signal at this time is stored locally in the neurostimulator.

[0008] Optionally, when at least one of the treatment parameters is greater than or equal to a preset value, the method further includes: The treatment parameter greater than or equal to the preset value is adjusted to less than the safety value, and the adjusted treatment parameter is input into the neurostimulator to control the neurostimulator to perform neurostimulation on the target head until the preset stimulation time is reached.

[0009] Optionally, controlling the nerve stimulation device to perform nerve stimulation on the target head until a preset stimulation time is reached, further comprising: Controlling the sensor to monitor the target body temperature and heart rate in real time, and when the target body temperature is greater than or equal to a preset value, controlling the neurostimulator to stop neurostimulating the target head, giving an abnormal alarm and storing the EEG signal at this time locally in the neurostimulator, and / or; When the target heart rate is greater than or equal to the preset value, the neurostimulator is controlled to stop neurostimulation on the target head, an abnormal alarm is issued and the EEG signal at this time is stored locally in the neurostimulator.

[0010] Optionally, the neurostimulator performs neurostimulation on the target head by outputting neurostimulation current.

[0011] Optionally, the neural stimulation modes include: transcranial direct current stimulation and transcranial alternating current stimulation, wherein transcranial direct current stimulation includes direct current stimulation, monophasic square wave stimulation and sham stimulation, and transcranial alternating current stimulation includes biphasic square wave stimulation and sinusoidal wave stimulation.

[0012] Optionally, neurostimulation devices are used to treat depression, anxiety, cognitive impairment, stroke, chronic pain, addictive behaviors, epilepsy, sleep disorders, ALS, and Parkinson's disease.

[0013] A nerve stimulation device, comprising: A startup module, used to start the nerve stimulation instrument and select a working mode, which includes a doctor mode and a user mode; The control module is used to control the neurostimulator to perform neurostimulation on the target head according to the treatment parameters pre-set by the doctor when the doctor mode is selected; and to control the neurostimulator to perform neurostimulation on the target head according to the treatment parameters set by the user when the user mode is selected.

[0014] In an embodiment of the present invention, by starting the neurostimulator and selecting a working mode, when the doctor mode is selected, the neurostimulator is controlled to perform neurostimulation on the target head according to the treatment parameters pre-set by the doctor; when the user mode is selected, the neurostimulator is controlled to perform neurostimulation on the target head according to the treatment parameters set by the user. This can flexibly adapt to the specific needs of different patients and give full play to the effectiveness of the treatment. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] In order to more clearly illustrate the technical solution of the present invention, the accompanying drawings required for use in the description of the present invention will be briefly introduced below. Obviously, the accompanying drawings in the following description are only some embodiments of the present invention. For ordinary technicians in this field, other accompanying drawings can be obtained based on these accompanying drawings without paying creative labor.

[0016] Figure 1 is a flowchart of the steps of a nerve stimulation method provided by one embodiment of the present invention; Figure 2 It is a schematic diagram of electrode placement provided by an embodiment of the present invention. DETAILED DESCRIPTION

[0017] In order to make the above-mentioned purposes, features and advantages of the present invention more obvious and easy to understand, the present invention is further described in detail below in conjunction with the accompanying drawings and specific embodiments. Obviously, the described embodiments are part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0018] Reference Figure 1 , shows a flowchart of a neural stimulation method provided by an embodiment of the present invention, which may specifically include the following steps: Step 101, start the nerve stimulation device and select the working mode.

[0019] In an embodiment of the present invention, the user can start the nerve stimulation instrument after connecting the electrode patch. After starting the nerve stimulation instrument, the user needs to select a working mode, which may include a doctor mode and a user mode.

[0020] Step 102, when the doctor mode is selected, the neurostimulator is controlled to perform neurostimulation on the target head according to the treatment parameters pre-set by the doctor; when the user mode is selected, the neurostimulator is controlled to perform neurostimulation on the target head according to the treatment parameters set by the user.

[0021] In an embodiment of the present invention, when the doctor mode is selected, a user account is logged in on the neurostimulator, the user account corresponds to the treatment parameters preset by the doctor, and the neurostimulator is controlled to perform neurostimulation on the target head according to the treatment parameters preset by the doctor until the preset stimulation time is reached; wherein the treatment parameters preset by the doctor are fixed values. When the user mode is selected, a neurostimulation mode is selected on the neurostimulator according to the target disease and the treatment parameters are set, and the neurostimulator is controlled to perform neurostimulation on the target head according to the treatment parameters set by the user until the preset stimulation time is reached.

[0022] It is understandable that doctors can pre-set relevant treatment parameters according to the specific conditions of patients and save them to the user account, so that users can directly complete the treatment through the nerve stimulation device after returning home. In this process, users do not need to adjust the treatment parameters themselves, that is, the treatment parameters pre-set by doctors are fixed values. On the one hand, it can improve the convenience of user operation, and on the other hand, it can also avoid user operation errors that lead to medical accidents.

[0023] In actual applications, as the patient's condition changes, the patient can choose to go to the hospital regularly to let the doctor reset the treatment parameters. However, in order to reduce unnecessary travel for patients, the embodiment of the present invention also provides a user mode, that is, the user can debug and set the treatment parameters by himself according to the patient's recovery condition.

[0024] In an embodiment of the present invention, when all treatment parameters are less than the safety value, the neurostimulator is controlled to perform neurostimulation on the target head until the preset stimulation time is reached; when at least one of the treatment parameters is greater than or equal to the safety value, the neurostimulator is controlled to stop neurostimulating the target head, an abnormal alarm is issued and the EEG signal at this time is stored locally in the neurostimulator.

[0025] In an embodiment of the present invention, a treatment parameter greater than or equal to a preset value may be adjusted to a value less than a safety value, and the adjusted treatment parameter may be input into a neurostimulator to control the neurostimulator to perform neurostimulation on the target head until a preset stimulation time is reached.

[0026] In an embodiment of the present invention, by starting the neurostimulator and selecting a working mode, when the doctor mode is selected, the neurostimulator is controlled to perform neurostimulation on the target head according to the treatment parameters pre-set by the doctor; when the user mode is selected, the neurostimulator is controlled to perform neurostimulation on the target head according to the treatment parameters set by the user. This can flexibly adapt to the specific needs of different patients and give full play to the effectiveness of the treatment.

[0027] In some other embodiments of the present invention, the following nerve stimulation methods may also be used: Step 201, generating an EEG signal for the target head in real time.

[0028] Specifically, it may include: The electrode patch is used to collect the original EEG signal of the target head in real time, and the original EEG signal is input into the amplifier. When the original EEG signal is amplified to a preset range, the amplified EEG signal is output, and the EEG signal output by the amplifier is filtered by a filter to generate a processed EEG signal.

[0029] In some embodiments of the present invention, an electrode patch may be connected to a nerve stimulation device, and then the electrode patch may be attached to the patient's head. Specifically, the electrode attachment may be performed by the following method: 1. International 10-20 system The international 10-20 system is based on anatomical landmarks of the head and divides the scalp into 10% and 20% intervals, with a total of 21 electrodes, such as Figure 2 The following are the detailed electrode placement steps: 1) Determine the baseline: Front-back line: Draw a front-back line from the root of the nose to the external occipital protuberance, and the length of this line is set to 100%.

[0030] Left-right connecting line: Draw a left-right connecting line between the left and right preauricular concavities, and the length of this connecting line is also set to 100%.

[0031] 2) Determine the midline electrode position: Cz electrode: The intersection of the front-to-back line and the left-to-right line is at the top of the head, which is the position of electrode Cz.

[0032] Fpz electrode: Along the front-to-back line, the position 10% of the distance from the root of the nose is determined as the Fpz electrode position.

[0033] Fz, Cz, Pz and Oz electrodes: An electrode position is defined every 20% of the distance from Fpz to the back, namely Fz, Cz, Pz and Oz from front to back, where the length of electrode Oz from the external occipital protuberance is 10%.

[0034] 3) Determine the position of the left and right connecting electrodes: T3 electrode: Along the left-right line, the position 10% from the left preauricular concave to the right is set as the T3 electrode position.

[0035] C3, Cz, C4 and T4 electrodes: An electrode is set every 20% of the distance from T3 to the right, from left to right, they are C3, Cz, C4 and T4, among which the length of the T4 electrode from the right preauricular notch is 10%.

[0036] 4) Determine the position of the left connecting electrode: Fp1 electrode: The point 10% posterior to Fpz is defined as the Fp1 electrode.

[0037] F7, T3, T5 and O1 electrodes: From Fp1 to the back, there is an electrode position every 20%, namely F7, T3, T5 and O1, where the distance between O1 and Oz is 10%.

[0038] 5) Determine the position of the right-side connecting electrode: Fp2 electrode: The point 10% posterior to Fpz is defined as the Fp2 electrode.

[0039] F8, T4, T6 and O2 electrodes: From Fp2 to the back, there is an electrode position every 20%, namely F8, T4, T6 and O2, where the distance between O2 and Oz is 10%.

[0040] 6) Determine the remaining electrode positions: F3 electrode: The intersection of the Fp1-C3-O1 line and the F7-Fz-F8 line is defined as electrode F3.

[0041] P3 electrode: The intersection of the Fp1-C3-O1 line and the T5-Pz-T6 line is defined as P3.

[0042] F4 and P4 electrodes: Similarly, the F4 and P4 electrodes on the right can be defined.

[0043] High-density electrode array High-density electrode arrays usually use 64, 128, 256 or even more electrodes, far more than the 21 electrodes in the international 10-20 system. The electrode placement method is also more flexible, including but not limited to: Grid arrangement: The electrodes are arranged in a grid pattern, evenly distributed on the scalp surface, such as 8x8, 16x8, 16x16, etc.

[0044] Specific area coverage: Patients can personalize the placement of electrode arrays in areas such as the frontal lobe, occipital lobe, parietal lobe or other brain structures based on the medical plan given by their doctor.

[0045] It is understandable that since the international 10-20 system only involves 21 electrodes, it is more convenient for patients to wear and adjust by themselves, and although the high-density electrode array is relatively troublesome to wear, it is more flexible in its placement, making it easier for patients to receive targeted treatment, and it involves a large number of electrodes, with a higher spatial resolution, and can capture more detailed brain electrical activity. Those skilled in the art can choose the placement method according to actual needs, and the present invention does not limit this.

[0046] In some embodiments of the present invention, an amplifier may be used to amplify the collected original EEG signal.

[0047] In actual applications, some patients may have weak EEG signals, but weak EEG signals may not be conducive to the subsequent prediction of treatment parameters. Therefore, the embodiment of the present invention can input the collected original EEG signals into the amplifier and amplify them to a preset range for further processing of the EEG signals.

[0048] It is understandable that the EEG signal output by the amplifier may have noise interference introduced by the amplifier itself, such as thermal noise and shot noise, or some noise interference may be introduced in the process of collecting the original EEG signal due to problems such as poor contact between the electrode and the scalp and electrode aging. Therefore, the embodiment of the present invention also uses a filter to filter the EEG signal output by the amplifier, which can effectively improve the quality of the EEG signal, make the subsequent predicted treatment parameters more accurate, and further improve the treatment effect of nerve stimulation.

[0049] Step 202: predicting treatment parameters based on the EEG signal.

[0050] As an embodiment of the present invention, treatment parameters may be predicted based on EEG signals, and the treatment parameters may include: current intensity, stimulation frequency, pulse width, etc., wherein the pulse width may include positive pulse width and negative pulse width.

[0051] After the above treatment parameters are predicted, they can be input into the neurostimulator. It should be understood that since the EEG signal is generated in real time, the treatment parameters predicted in different time periods will also change. In practical applications, the treatment parameters predicted in different time periods need to be continuously input into the neurostimulator to achieve dynamic adjustment of the treatment parameters, so as to ensure that the current treatment parameters can achieve the best treatment effect according to the patient's real-time status.

[0052] In some embodiments of the present invention, the EEG signal can be input into a trained convolutional neural network model, and the convolutional neural network model can be used to predict treatment parameters.

[0053] As a deep learning algorithm, convolutional neural network can achieve accurate prediction of treatment parameters. Compared with the traditional way of adjusting treatment parameters, that is, doctors give adjusted treatment parameters in the medical plan based on the patient's condition, the use of convolutional neural network to automatically predict treatment parameters can effectively improve the efficiency of treatment, without the need for patients to go to the hospital or clinic many times to ask doctors for help in adjusting treatment parameters. Moreover, in actual applications, some doctors often adjust treatment parameters based on their medical experience, but due to differences in the conditions of different patients, it is difficult for some doctors to guarantee that the treatment parameters they provide can achieve the best treatment effect.

[0054] In addition, in the embodiments of the present invention, the real-time generated EEG signals can also be stored as new training data in the training set of the convolutional neural network, thereby realizing continuous optimization of the convolutional neural network model and improving its generalization ability.

[0055] Step 203, controlling the nerve stimulation device to perform nerve stimulation on the target head until a preset stimulation time is reached.

[0056] In some embodiments of the present invention, the nerve stimulation apparatus may record the user's frequently used stimulation time according to the user's habits, and set the frequently used stimulation time as the default stimulation time.

[0057] For example, user A uses the neurostimulator to treat epilepsy 5 times, and the stimulation time is set to 30 minutes for 4 of the times. When user A uses the neurostimulator to treat epilepsy again, the default stimulation time will be set to 30 minutes. If user A uses the neurostimulator to treat epilepsy 10 times, and the stimulation time is set to 30 minutes for 5 of the times and 20 minutes for the other 5 times, when user A uses the neurostimulator to treat epilepsy again, the default stimulation time may be randomly set to 20 minutes or 30 minutes.

[0058] It is understandable that before using the neurostimulator for treatment, the user needs to log in his or her user information to facilitate the neurostimulator to read the user's habits.

[0059] In some embodiments of the present invention, controlling a neurostimulator to perform neurostimulation on a target head until a preset stimulation time is reached may include: when several predicted treatment parameters are all less than preset values, inputting the treatment parameters into the neurostimulator, and controlling the neurostimulator to perform neurostimulation on the target head until the preset stimulation time is reached; when at least one of the predicted treatment parameters is greater than or equal to the preset value, controlling the neurostimulator to stop neurostimulating the target head, issuing an abnormal alarm and storing the EEG signal at this time locally in the neurostimulator.

[0060] To ensure patient safety, the embodiment of the present invention further sets a threshold value for the treatment parameter and uses the threshold value as a preset value, wherein the threshold value for the treatment parameter can also be obtained through a convolutional neural network model.

[0061] When all the predicted treatment parameters are less than the preset values, that is, the treatment parameters such as current intensity are within the patient's tolerance range, the treatment parameters are input into the neurostimulator, and the neurostimulator is controlled to perform neurostimulation on the target head until the preset stimulation time is reached.

[0062] When a certain predicted treatment parameter is equal to the preset value, it means that the patient's tolerance has reached the critical value. The neurostimulator is controlled to stop neurostimulation on the target head to avoid sudden situations that break the above critical value and cause damage to the patient's body. The EEG signal at this time is recorded and stored locally in the neurostimulator, so that the patient can go to the hospital or clinic to feedback the above abnormal conditions to the doctor for further targeted treatment.

[0063] Similarly, when a predicted treatment parameter is greater than a preset value, it means that the patient cannot withstand the upcoming neurostimulation, and the neurostimulator is controlled to stop neurostimulating the target head, an abnormal alarm is issued, and the EEG signal at this time is stored locally in the neurostimulator.

[0064] In practical applications, in addition to storing the above-mentioned EEG signals locally in the neural stimulation instrument, they can also be stored in the cloud. Those skilled in the art can make their own choices based on actual conditions, and the embodiments of the present invention do not limit this.

[0065] Furthermore, when at least one of the predicted treatment parameters is greater than or equal to a preset value, it also includes: adjusting the treatment parameter greater than or equal to the preset value to less than the preset value, and inputting the adjusted treatment parameter into the neurostimulator, and controlling the neurostimulator to perform neurostimulation on the target head until the preset stimulation time is reached.

[0066] It is understandable that if the neurostimulator is controlled to stop performing neurostimulation on the target head before the preset stimulation time is reached, the treatment effect may be affected to a certain extent. Therefore, the embodiment of the present invention also proposes that when at least one of the predicted treatment parameters is greater than or equal to the preset value, the treatment parameter greater than or equal to the preset value is adjusted to less than the preset value, and the adjusted treatment parameter is input into the neurostimulator, and the neurostimulator is controlled to perform neurostimulation on the target head until the preset stimulation time is reached, which can ensure that the treatment effect is maximized within a safe range.

[0067] In actual applications, due to the differences in the physical conditions of each patient, the treatment parameters may not reach the preset values, but the patient's heart rate or body temperature may increase significantly. It is understandable that heart rate and body temperature are the most intuitive reflections of the patient's physiological state, which can be used to assess whether the patient is able to withstand further neural stimulation. In order to avoid causing damage to the patient's body, the embodiment of the present invention can also control the sensor to monitor the target body temperature and heart rate in real time. When the target body temperature is greater than or equal to the preset value, the neural stimulation instrument is controlled to stop neural stimulation of the target head, an abnormal alarm is issued, and the EEG signal at this time is stored locally in the neural stimulation instrument, and / or; when the target heart rate is greater than or equal to the preset value, the neural stimulation instrument is controlled to stop neural stimulation of the target head, an abnormal alarm is issued, and the EEG signal at this time is stored locally in the neural stimulation instrument.

[0068] In some embodiments of the present invention, the nerve stimulation apparatus can perform nerve stimulation on the target head by outputting a nerve stimulation current. Specifically, the nerve stimulation current can include direct current and alternating current.

[0069] In some embodiments of the present invention, the neural stimulation modes include: transcranial direct current stimulation (TDCS) and transcranial alternating current stimulation (TDAS), wherein transcranial direct current stimulation includes direct current stimulation, monophasic square wave stimulation and sham stimulation, and transcranial alternating current stimulation includes biphasic square wave stimulation and sinusoidal wave stimulation.

[0070] In some embodiments of the present invention, the neurostimulation apparatus may be used to treat depression, anxiety, cognitive impairment, stroke, chronic pain, addictive behavior, epilepsy, sleep disorders, ALS, and Parkinson's disease.

[0071] Among them, a monophasic square wave is a current waveform characterized by the current flowing in only one direction in each cycle, after which the current returns to zero. In monophasic square wave stimulation, the direction of the current is usually unidirectional, that is, the current flows in only one direction during the stimulation process. Specifically, the current can flow from the positive electrode (anode) to the negative electrode (cathode), or vice versa. The direction of the current depends on the polarity of the electrode and the setting of the stimulation parameters.

[0072] Sham stimulation is a commonly used control method in clinical trials or studies to evaluate the true effect of a treatment or intervention. The purpose of sham stimulation is to simulate the feeling or process of actual treatment, but without producing actual treatment effects, thereby helping researchers distinguish the true effect of treatment from placebo effects or other non-specific effects. In general, the waveform of sham stimulation is no different from a direct current waveform.

[0073] In actual application, after applying the electrode patches, the patient can turn on the neurostimulator, log in his user information, and then select the corresponding indication based on his conscious choice.

[0074] In an embodiment of the present invention, by generating EEG signals for the target head in real time; predicting treatment parameters based on the EEG signals; using the treatment parameters to dynamically adjust the neurostimulation instrument; and controlling the neurostimulation instrument to perform neurostimulation on the target head until a preset stimulation time is reached, the number of times patients go to the hospital or clinic can be effectively reduced, and the patient's medical experience can be significantly improved. Moreover, this method can fine-tune the treatment parameters in real time according to changes in the patient's condition, and can effectively avoid problems such as physical discomfort in the patient caused by excessive changes in the treatment parameters.

[0075] It should be noted that, for the sake of simplicity, the method embodiments are described as a series of action combinations, but those skilled in the art should be aware that the embodiments of the present invention are not limited by the order of the actions described, because according to the embodiments of the present invention, certain steps can be performed in other orders or simultaneously. Secondly, those skilled in the art should also be aware that the embodiments described in the specification are all preferred embodiments, and the actions involved are not necessarily required by the embodiments of the present invention.

[0076] The present invention also provides a neural stimulation device, which may include the following modules: A start module 301 is used to start the nerve stimulation device and select a working mode, wherein the working modes include a doctor mode and a user mode; The control module 302 is used to control the neurostimulator to perform neurostimulation on the target head according to the treatment parameters pre-set by the doctor when the doctor mode is selected; and to control the neurostimulator to perform neurostimulation on the target head according to the treatment parameters set by the user when the user mode is selected.

[0077] In another embodiment of the present invention, the nerve stimulation device may further include the following modules: A generating module 401 is used to generate an EEG signal for a target head in real time; Prediction module 402, used to predict treatment parameters based on EEG signals; treatment parameters are used to dynamically adjust the neural stimulation instrument; The control module 403 is used to control the nerve stimulation device to perform nerve stimulation on the target head until a preset stimulation time is reached.

[0078] Optionally, the generating module 401 includes: The EEG signal acquisition submodule is used to use electrode patches to collect the original EEG signals of the target head in real time; input the original EEG signals into the amplifier, and when the original EEG signals are amplified to a preset range, the amplified EEG signals are output; and the EEG signals output by the amplifier are filtered using a filter to generate processed EEG signals.

[0079] Optionally, the prediction module 402 includes: The EEG signal input submodule is used to input the EEG signal into the trained convolutional neural network model and use the convolutional neural network model to predict treatment parameters.

[0080] Optionally, the control module 403 includes: The treatment parameter judgment submodule is used to input the treatment parameters into the neurostimulator when all the predicted treatment parameters are less than the preset values, and control the neurostimulator to perform neurostimulation on the target head until the preset stimulation time is reached; when at least one of the predicted treatment parameters is greater than or equal to the preset value, control the neurostimulator to stop neurostimulating the target head, issue an abnormal alarm and store the EEG signal at this time locally in the neurostimulator.

[0081] Optionally, the treatment parameter determination submodule further includes: The treatment parameter adjustment unit is used to adjust the treatment parameter greater than or equal to the preset value to less than the preset value, and input the adjusted treatment parameter to the neurostimulation instrument to control the neurostimulation instrument to perform neurostimulation on the target head until the preset stimulation time is reached.

[0082] Optionally, the treatment parameter adjustment unit further includes: The sensor control subunit is used to control the sensor to monitor the target body temperature and heart rate in real time. When the target body temperature is greater than or equal to a preset value, the sensor controls the neurostimulator to stop neurostimulation on the target head, issues an abnormal alarm and stores the EEG signal locally on the neurostimulator, and / or; when the target heart rate is greater than or equal to a preset value, the sensor controls the neurostimulator to stop neurostimulation on the target head, issues an abnormal alarm and stores the EEG signal locally on the neurostimulator.

[0083] Optionally, the neural stimulation modes include: transcranial direct current stimulation and transcranial alternating current stimulation, wherein transcranial direct current stimulation includes direct current stimulation, monophasic square wave stimulation and sham stimulation, and transcranial alternating current stimulation includes biphasic square wave stimulation and sinusoidal wave stimulation.

[0084] Optionally, neurostimulation devices are used to treat depression, anxiety, cognitive impairment, stroke, chronic pain, addictive behaviors, epilepsy, sleep disorders, ALS, and Parkinson's disease.

[0085] As for the device embodiment, since it is basically similar to the method embodiment, the description is relatively simple, and the relevant parts can be referred to the partial description of the method embodiment.

[0086] The various embodiments in this specification are described in a progressive manner, and each embodiment focuses on the differences from other embodiments. The same or similar parts between the various embodiments can be referenced to each other.

[0087] Although the preferred embodiments of the present invention have been described, those skilled in the art may make additional changes and modifications to these embodiments once they have learned the basic creative concept. Therefore, the appended claims are intended to be interpreted as including the preferred embodiments and all changes and modifications that fall within the scope of the embodiments of the present invention.

[0088] The above provides a detailed introduction to a neural stimulation method and device thereof. Specific examples are used herein to illustrate the principles and implementation methods of the present invention. The description of the above embodiments is only used to help understand the method of the present invention and its core idea. At the same time, for those skilled in the art, according to the idea of ​​the present invention, there will be changes in the specific implementation methods and application scopes. In summary, the content of this specification should not be understood as a limitation on the present invention.

Claims

1. A method for nerve stimulation, characterized in that: The method comprises: Starting the nerve stimulation device and selecting a working mode, wherein the working mode includes a doctor mode and a user mode; When the doctor mode is selected, the nerve stimulation device is controlled to perform nerve stimulation on the target head according to the treatment parameters preset by the doctor; When the user mode is selected, the neurostimulation device is controlled to perform neurostimulation on the target head according to the treatment parameters set by the user.

2. The method according to claim 1, characterized in that When the doctor mode is selected, controlling the nerve stimulation device to perform nerve stimulation on the target head according to the treatment parameters preset by the doctor includes: In the case of selecting the doctor mode, a user account is logged in on the neurostimulator, the user account corresponds to the treatment parameters preset by the doctor, and the neurostimulator is controlled to perform neurostimulation on the target head according to the treatment parameters preset by the doctor until the preset stimulation time is reached; Among them, the treatment parameters preset by the doctor are fixed values.

3. The method according to claim 2, characterized in that When the user mode is selected, controlling the nerve stimulation apparatus to perform nerve stimulation on the target head according to the treatment parameters set by the user includes: When the user mode is selected, a neurostimulation mode is selected on the neurostimulation instrument according to the target disease and treatment parameters are set, and the neurostimulation instrument is controlled to perform neurostimulation on the target head according to the treatment parameters set by the user until a preset stimulation time is reached.

4. The method according to claim 3, characterized in that The step of performing nerve stimulation on the target head until a preset stimulation time is reached includes: When all the treatment parameters are less than the safety value, controlling the nerve stimulation device to perform nerve stimulation on the target head until a preset stimulation time is reached; When at least one of the treatment parameters is greater than or equal to a safety value, the neurostimulator is controlled to stop neurostimulation of the target head, an abnormal alarm is issued, and the EEG signal at this time is stored locally in the neurostimulator.

5. The method according to claim 4, characterized in that When at least one of the treatment parameters is greater than or equal to the safety value, the method further comprises: The treatment parameter greater than or equal to the preset value is adjusted to be less than the safety value, and the adjusted treatment parameter is input into the neurostimulation device, and the neurostimulation device is controlled to perform neurostimulation on the target head until the preset stimulation time is reached.

6. The method according to claim 5, characterized in that The controlling the nerve stimulation apparatus to perform nerve stimulation on the target head until a preset stimulation time is reached also includes: Controlling the sensor to monitor the target body temperature and heart rate in real time, and when the target body temperature is greater than or equal to a preset value, controlling the neurostimulator to stop neurostimulating the target head, giving an abnormal alarm and storing the EEG signal at this time locally in the neurostimulator, and / or; When the target heart rate is greater than or equal to a preset value, the neurostimulator is controlled to stop neurostimulation of the target head, an abnormal alarm is issued, and the EEG signal at this time is stored locally in the neurostimulator.

7. The method according to claim 3, characterized in that The neurostimulation device performs neurostimulation on the target head by outputting a neurostimulation current.

8. The method according to claim 7, characterized in that The neural stimulation modes include: transcranial direct current stimulation and transcranial alternating current stimulation, wherein the transcranial direct current stimulation includes direct current stimulation, monophasic square wave stimulation and sham stimulation, and the transcranial alternating current stimulation includes biphasic square wave stimulation and sinusoidal wave stimulation.

9. The method according to claim 8, characterized in that The neurostimulation device is used to treat depression, anxiety, cognitive impairment, stroke, chronic pain, addictive behavior, epilepsy, sleep disorders, ALS and Parkinson's disease.

10. A nerve stimulation device, characterized in that: The device comprises: A start-up module, used to start the nerve stimulation instrument and select a working mode, wherein the working mode includes a doctor mode and a user mode; The control module is used to control the neurostimulator to perform neurostimulation on the target head according to the treatment parameters preset by the doctor when the doctor mode is selected; and to control the neurostimulator to perform neurostimulation on the target head according to the treatment parameters set by the user when the user mode is selected.

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