Extraction separation device and extraction separation system

Abstract

The embodiment of the invention provides an extraction separation device and an extraction separation system, the extraction separation device comprises a body part and a separation membrane, and the body part comprises a liquid inlet, a first channel, a second channel, a third channel, a fourth channel, a mixing cavity, a separation cavity, a first liquid storage cavity and a second liquid storage cavity. The liquid inlet is formed in the outer surface of the body part. And the liquid inlet is communicated with the mixing cavity through the first channel. The separation membrane is arranged in the separation cavity and divides the separation cavity into a first sub-cavity and a second sub-cavity, the first sub-cavity is communicated with the mixing cavity through the second channel, and the separation membrane is used for preventing the non-organic phase in the first sub-cavity from entering the second sub-cavity. And the first liquid storage cavity is communicated with the second sub-cavity through a third channel. And the second liquid storage cavity is communicated with the first sub-cavity through a fourth channel. The extraction and separation device provided by the embodiment of the invention is compact in structure, the organic phase and the non-organic phase of the separation cavity are primarily separated through the separation membrane, and the separation efficiency and the purity are improved.

Description

Technical Field

[0001] The present application relates to the technical field of extraction and separation, and in particular to an extraction and separation device and an extraction and separation system. Background Art

[0002] In the post-processing sample analysis, due to the complex composition of the sample, the sample needs to be pre-treated before detection. Liquid-liquid extraction is often used as a pre-treatment method. The complex properties of organic solvents and actinides of different valence states can be used to separate the components to be tested from the matrix. The extraction equipment in the related technology has a complex structure and has the problem of low efficiency in extraction, separation and measurement. Summary of the invention

[0003] In view of this, the embodiments of the present application provide an extraction and separation device and an extraction and separation system for simplifying the work of extraction and separation and measurement and improving separation efficiency.

[0004] To achieve the above-mentioned purpose, the first aspect of the embodiment of the present application provides an extraction separation device, the extraction separation device comprises a main body and a separation membrane, the main body comprises:

[0005] A liquid inlet, the liquid inlet being arranged on the outer surface of the main body;

[0006] a first channel and a mixing chamber, wherein the liquid inlet is connected to the mixing chamber through the first channel;

[0007] a second channel and a separation chamber, wherein the separation membrane is disposed in the separation chamber and divides the separation chamber into a first sub-chamber and a second sub-chamber, the first sub-chamber is connected to the mixing chamber through the second channel, and the separation membrane is used to prevent the non-organic phase in the first sub-chamber from entering the second sub-chamber;

[0008] a third channel and a first liquid storage chamber, wherein the first liquid storage chamber is connected with the second sub-chamber through the third channel;

[0009] A fourth channel and a second liquid storage chamber, wherein the second liquid storage chamber is connected with the first sub-chamber through the fourth channel.

[0010] In one embodiment, the first liquid storage chamber and the second liquid storage chamber are arranged on both sides of the main body along the length direction, and the mixing chamber and the separation chamber are arranged between the first liquid storage chamber and the second liquid storage chamber.

[0011] In one embodiment, the main body comprises an air outlet, the air outlet is arranged on the outer surface of the main body, and the air outlet is communicated with the mixing chamber; and / or,

[0012] A buffer chamber is defined inside the main body, the second channel penetrates the buffer chamber, and the mixed phase flowing out of the mixing chamber is stored in the buffer chamber.

[0013] In one embodiment, the separation chamber extends in an S-shape.

[0014] In one embodiment, the flow channel length of the separation chamber is greater than or equal to 1 cm and less than or equal to 1.5 cm; and / or,

[0015] The equivalent diameter of the flow cross section of the separation chamber is greater than or equal to 450 nm and less than or equal to 800 nm.

[0016] In one embodiment, the material of the separation membrane includes polytetrafluoroethylene; and / or,

[0017] The material of the main body includes polymethyl methacrylate; and / or,

[0018] The volume of the mixing chamber is greater than or equal to 3 cm 3 , and less than or equal to 3.2cm 3 .

[0019] In one embodiment, the main body portion includes a first body and a second body arranged along a thickness direction.

[0020] In one embodiment, the first body is connected to the second body by thermocompression bonding; and / or,

[0021] The main body portion includes a third body, and the third body is connected to the second body by thermocompression bonding.

[0022] In one embodiment, the extraction and separation device comprises a polycarbonate membrane, and the polycarbonate membrane seals the first liquid storage chamber and / or the second liquid storage chamber.

[0023] A second aspect of the embodiments of the present application provides an extraction and separation system, the extraction and separation system comprising an X-ray tube, a detector, a drive assembly and an extraction and separation device as described in any embodiment of the present application;

[0024] The driving assembly is used to drive the first liquid storage chamber or the second liquid storage chamber of the extraction and separation device to be close to or away from the X-ray tube, the X-ray tube irradiates the phase to be detected in the first liquid storage chamber or the second liquid storage chamber, and the detector detects the components of the phase to be detected.

[0025] The extraction and separation device provided in the embodiment of the present application integrates a liquid inlet, multiple channels, a mixing chamber, a separation chamber, a liquid storage chamber and other components in the main body, so that the entire device has a compact structure. After the liquid to be separated enters from the liquid inlet, it is processed by the mixing chamber and the separation chamber in turn, and finally flows into the corresponding liquid storage chamber respectively, so as to achieve the separation and purification of the target substance. The separation chamber is divided into two sub-chambers by a separation membrane, which can effectively prevent the non-organic phase in the first sub-chamber from entering the second sub-chamber, realize the preliminary separation of the organic phase and the non-organic phase, and improve the separation efficiency and purity. The first liquid storage chamber and the second liquid storage chamber are used to store the organic phase and the non-organic phase respectively, which is also conducive to the classified storage of the components in the solution, thereby improving the accuracy of the detection. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figure 1 This is a schematic diagram of the structure of an extraction and separation system in one embodiment of the present application;

[0027] Figure 2 This is a schematic diagram of the structure of an extraction and separation device in one embodiment of the present application;

[0028] Figure 3 for Figure 2 Schematic diagram of the structure of the middle buffer cavity;

[0029] Figure 4 for Figure 2 Schematic diagram of the structure of the separation chamber;

[0030] Figure 5 for Figure 4 Cross-sectional view of the separation chamber.

[0031] Description of Reference Numerals

[0032] 1000, extraction and separation system; 100, extraction and separation device; 10, main body; 101, liquid inlet; 102, first channel; 103, second channel; 104, third channel; 105, fourth channel; 106, mixing chamber; 107, separation chamber; 1071, first sub-chamber; 1072, second sub-chamber; 108, first liquid storage chamber; 109, second liquid storage chamber; 110, buffer chamber; 111, first body; 112, second body; 113, third body; 114, gas outlet; 20, separation membrane; 30, polycarbonate membrane; 200, X-ray tube; 300, detector; 400, drive assembly. DETAILED DESCRIPTION

[0033] It should be noted that, in the absence of conflict, the embodiments in this application and the technical features in the embodiments can be combined with each other, and the detailed description in the specific implementation method should be understood as an explanation of the purpose of this application and should not be regarded as an improper limitation on this application.

[0034] In the description of the embodiments of the present application, it should be noted that the orientations or positional relationships indicated by the terms "transmission direction of rays", "thickness direction", "first direction", "second direction", etc. are based on the orientations or positional relationships shown in the drawings. These orientation terms are only for the convenience of describing the embodiments of the present application and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the embodiments of the present application. The present application will be further described in detail below in conjunction with the drawings and specific embodiments.

[0035] The present application embodiment provides an extraction separation device 100, see Figure 2 The extraction separation device 100 includes a body 10 and a separation membrane 20. The body 10 includes a liquid inlet 101, a first channel 102, a second channel 103, a third channel 104, a fourth channel 105, a mixing chamber 106, a separation chamber 107, a first liquid storage chamber 108, and a second liquid storage chamber 109. The liquid inlet 101 is arranged on the outer surface of the body 10. The liquid inlet 101 is connected to the mixing chamber 106 through the first channel 102. The separation membrane 20 is arranged in the separation chamber 107, and divides the separation chamber 107 into a first sub-chamber 1071 and a second sub-chamber 1072. The first sub-chamber 1071 is connected to the mixing chamber 106 through the second channel 103. The separation membrane 20 is used to prevent the non-organic phase in the first sub-chamber 1071 from entering the second sub-chamber 1072. The first liquid storage chamber 108 is connected to the second sub-chamber 1072 through the third channel 104. The second liquid storage chamber 109 is in communication with the first sub-chamber 1071 through the fourth channel 105 .

[0036] The extraction separation device 100 is a device specially used to separate different components in a mixture. Through a specific structure and principle, it uses the characteristics of the difference in solubility of a substance in different phases or media to achieve the separation purpose.

[0037] The extraction separation device 100 includes a main body 10 and a separation membrane 20 . The main body 10 includes a liquid inlet 101 , a first channel 102 , a second channel 103 , a third channel 104 , a fourth channel 105 , a mixing chamber 106 , a separation chamber 107 , a first liquid storage chamber 108 , and a second liquid storage chamber 109 .

[0038] The body 10 is the main structural part of the extraction and separation device 100, carrying other components and providing space and channels for the flow and separation process of the liquid.

[0039] The liquid inlet 101 is located at the entrance of the outer surface of the main body 10 and is the starting point of the channel for the liquid to be treated to enter the interior of the device.

[0040] For example, the liquid inlet 101 may be provided with a filtering device to prevent impurities from entering the device to affect the separation effect and damage internal components. For example, a multi-layer filter structure may be used to perform graded filtering on impurities of different particle sizes.

[0041] For example, the liquid dispenser is used to compress the air to push the liquid forward. The size of the liquid inlet 101 is designed to match the size of the liquid dispenser tip. The operator only needs to keep pressing the liquid dispenser slowly to complete the liquid injection. The operation is simple and does not require an external driving device. The only problem is that the liquid dispenser tip is contaminated.

[0042] The first channel 102 is a pipe or passage connecting the liquid inlet 101 and the mixing chamber 106 , so that the liquid entering from the liquid inlet 101 can be smoothly transferred to the mixing chamber 106 .

[0043] For example, a flow regulating device, such as a regulating valve or a combination of a flow meter and a regulating valve, may be installed in the first channel 102 to accurately control the flow of liquid entering the mixing chamber 106 and ensure the stability and repeatability of the mixing process.

[0044] The size of the first channel 102 is determined according to actual needs and is not limited here. For example, the first channel 102 is a rectangular cavity with a length and width of 300 μm and a depth of 300 μm.

[0045] The second channel 103 is a channel connecting the mixing chamber 106 and the first sub-chamber 1071 in the separation chamber 107, and is used to introduce the liquid in the mixing chamber 106 into the first sub-chamber 1071 of the separation chamber 107 for preliminary separation treatment.

[0046] The size of the second channel 103 is determined according to actual needs and is not limited here. For example, the second channel 103 is a rectangular cavity with a length and width of 250 μm and a depth of 250 μm.

[0047] The third channel 104 is a channel connecting the second sub-chamber 1072 in the separation chamber 107 and the first liquid storage chamber 108. After being processed by the separation membrane 20, the specific liquid in the second sub-chamber 1072 can flow into the first liquid storage chamber 108 through the third channel 104 for storage.

[0048] The fourth channel 105 is a channel connecting the first sub-chamber 1071 in the separation chamber 107 and the second liquid storage chamber 109 . The remaining liquid in the first sub-chamber 1071 can flow into the second liquid storage chamber 109 through the fourth channel 105 .

[0049] The mixing chamber 106 is a cavity space used to preliminarily mix the liquid entering the device, thereby providing a uniform material basis for the subsequent separation process.

[0050] In some embodiments, a stirring device, such as a mechanical stirring paddle or a magnetic stirrer, may be provided inside the mixing chamber 106 to fully mix the incoming liquid and improve the subsequent separation efficiency. The shape and material of the stirring paddle may be selected according to the properties of the liquid to be processed. For example, a stirring paddle made of corrosion-resistant material may be used for corrosive liquids.

[0051] The separation chamber 107 is the core area for performing separation operations in the device, and is divided into two sub-chambers by the separation membrane 20 to achieve separation of different phases or components.

[0052] The first liquid storage chamber 108 is a chamber for storing a specific liquid that flows out of the second sub-chamber 1072 of the separation chamber 107 after being processed by the separation membrane 20 .

[0053] The second liquid storage chamber 109 is a chamber used to store the remaining liquid flowing out of the first sub-chamber 1071 of the separation chamber 107 .

[0054] Exemplarily, the first liquid storage chamber 108 and the second liquid storage chamber 109 are rectangular parallelepiped chambers with a length of 11 mm, a width of 2 mm, and a depth of 7 mm.

[0055] The separation membrane 20 is a thin film material with a selective permeability function. In this extraction separation device 100, it plays a key separation role. Its main function is to prevent the non-organic phase in the first sub-chamber 1071 from entering the second sub-chamber 1072, thereby achieving the separation of the organic phase and the non-organic phase. This selective permeability is based on the differences in the physical and chemical properties of different substances, such as molecular size, charge, solubility, etc.

[0056] The separation membrane 20 has a certain pore size. If the size of the non-organic phase molecules is larger than the pore size of the membrane, and the size of the organic phase molecules is smaller than the pore size of the membrane, then driven by the pressure difference or concentration difference, the organic phase molecules can pass through the membrane into the second sub-chamber 1072, while the non-organic phase molecules are blocked in the first sub-chamber 1071. For example, when treating a mixed solution containing large molecular proteins (non-organic phase) and small molecular organic compounds, the membrane can block the protein molecules and allow the small molecular organic compounds to pass through.

[0057] The separation membrane 20 should have certain chemical stability and physical stability. The separation membrane 20 should be able to maintain its performance under different chemical environments (such as acid, alkali, organic solvent, etc.). The separation membrane 20 should also maintain structural integrity under the influence of physical factors such as pressure and temperature changes. For example, when treating a mixed solution containing strong acid or alkalinity, the separation membrane 20 needs to have good chemical stability to prevent the membrane from degradation and performance degradation.

[0058] For example, the separation membrane 20 can adopt a multi-layer composite structure, which can not only block the non-organic phase, but also further separate the specific organic phase. For example, a layer of material having a selective adsorption function for specific small molecule organic compounds is composited on one side of the separation membrane 20 to improve the separation accuracy.

[0059] The working principle of the extraction separation device 100 of this embodiment is described below. The liquid and organic solvent to be separated can be injected into the mixing chamber 106 through the liquid inlet 101 and the first channel 102, and mixed in the mixing chamber 106 through the oscillation effect. After the liquid and organic solvent to be separated are mixed to form a mixed phase, the mixing chamber 106 can be pressurized at a suitable pipeline or component connected to the mixing chamber 106, for example, pressurized at the liquid inlet 101, and the mixed phase in the mixing chamber 106 is pushed along the second channel 103 into the first sub-chamber 1071 of the separation chamber 107. Under the action of pressure, the components in the mixed phase that can be dissolved in the organic solvent pass through the separation membrane 20 together with the organic solvent, enter the second sub-chamber 1072 to form an organic phase, and the organic phase enters the first liquid storage chamber 108 through the third channel 104 for storage. On the other hand, the substances in the mixed phase that cannot pass through the separation membrane 20 and water form a non-organic phase together, and the non-organic phase enters the second liquid storage chamber 109 through the fourth channel 105 for storage.

[0060] The extraction and separation device 100 provided in the embodiment of the present application integrates the liquid inlet 101, multiple channels, the mixing chamber 106, the separation chamber 107 and the liquid storage chamber and other components in the main body 10, so that the entire device has a compact structure. After the liquid to be separated enters from the liquid inlet 101, it is processed by the mixing chamber 106 and the separation chamber 107 in turn, and finally flows into the corresponding liquid storage chamber respectively, so as to achieve the separation and purification of the target substance. The separation chamber 107 is divided into two sub-chambers by the separation membrane 20, which can effectively prevent the non-organic phase in the first sub-chamber 1071 from entering the second sub-chamber 1072, so as to achieve the preliminary separation of the organic phase and the non-organic phase, and improve the separation efficiency and purity. The first liquid storage chamber 108 and the second liquid storage chamber 109 are used to store the organic phase and the non-organic phase respectively, which is also conducive to the classified storage of the components in the solution, thereby improving the accuracy of the detection.

[0061] In some embodiments, see Figure 2 The first liquid storage chamber 108 and the second liquid storage chamber 109 are arranged on both sides of the main body 10 along the length direction, and the mixing chamber 106 and the separation chamber 107 are arranged between the first liquid storage chamber 108 and the second liquid storage chamber 109 .

[0062] The length direction of the main body 10 refers to the direction of the longer dimension of the overall shape of the main body 10 as shown in the drawings, and the relative position layout of each component is determined based on this direction.

[0063] The first liquid storage chamber 108 and the second liquid storage chamber 109 are arranged on both sides along the length direction of the main body 10, and the mixing chamber 106 and the separation chamber 107 are in the middle, so that the layout of the entire device is more regular and compact. The connecting channels between the various components can be more reasonably planned, reducing the bends and length of the pipeline, reducing the liquid flow resistance, facilitating the smooth transmission of the liquid, and improving the efficiency of extraction and separation.

[0064] This layout makes each functional area relatively independent and clearly defined. During the maintenance and overhaul of the equipment, operators can more conveniently inspect, repair or replace different components. For example, if the first liquid storage chamber 108 or the second liquid storage chamber 109 leaks, it can be handled more conveniently from both sides of the main body 10 without excessively interfering with the normal operation of the mixing chamber 106 and the separation chamber 107 in the middle.

[0065] The mixing chamber 106 and the separation chamber 107 are arranged adjacent to each other, which can reduce the energy loss and possible composition changes in the process of the mixed phase being transferred from the mixing chamber 106 to the separation chamber 107. Moreover, the separation chamber 107 is located in the middle position, and its two sides are respectively connected to the first liquid storage chamber 108 and the second liquid storage chamber 109 through the third channel 104 and the fourth channel 105. Such a layout is conducive to accurately controlling the flow direction and flow rate of the organic phase and the non-organic phase as needed during the separation process, and further improving the separation accuracy and effect.

[0066] In some embodiments, see Figure 2 The main body 10 includes an air outlet 114 , which is disposed on the outer surface of the main body 10 and communicates with the mixing chamber 106 .

[0067] The structure of the air outlet 114 is not limited here. The air outlet 114 can be directly connected to the mixing chamber 106, or can be connected to the mixing chamber 106 through a structure on the main body 10 that is connected to the mixing chamber 106 to achieve indirect connection.

[0068] The provision of the air outlet 114 allows the gas inside the main body 10 to be discharged from the air outlet 114 when the liquid inlet 101 is taking in liquid, thereby ensuring the balance of the internal and external air pressures of the main body 10 and helping to reduce the resistance to liquid inlet.

[0069] In addition, the presence of the gas outlet 114 allows the gas generated in the device to be discharged, effectively preventing the pressure increase caused by gas accumulation. Timely discharge of the gas generated in the mixing chamber 106 can avoid potential safety risks caused by gas accumulation, such as dangerous situations such as device rupture or explosion caused by excessive pressure. The normal operation of the gas outlet 114 can improve the safety of the device.

[0070] It should be noted that when the mixing chamber 106 is pressurized, the gas outlet 114 may be blocked to ensure the pressure in the mixing chamber 106 .

[0071] In some embodiments, see Figures 2 to 3 A buffer chamber 110 is defined inside the main body 10 , and the second channel 103 penetrates the buffer chamber 110 . The mixed phase flowing out of the mixing chamber 106 is stored in the buffer chamber 110 .

[0072] The buffer chamber 110 is a cavity space defined by a specific structure inside the main body 10, which is mainly used to temporarily contain and buffer substances. In this context, it is used to store the mixed phase flowing out of the first liquid storage chamber 108, and plays a role in regulating flow, stabilizing system pressure and providing temporary storage space for subsequent further processing.

[0073] The specific structure of the buffer chamber 110 is not limited here. Exemplarily, the buffer chamber 110 is a tortuous structure extending in an S shape, which can increase the storage volume of the mixed phase in the buffer chamber 110 and increase the flow resistance of the mixed phase.

[0074] The buffer chamber 110 can accommodate the mixed phase flowing out of the mixing chamber 106, preventing the mixed phase from directly and quickly flowing into the separation chamber 107, thereby effectively buffering the fluctuation of the flow rate and making the mixed phase flow rate entering the separation chamber 107 more stable and uniform. At the same time, it also helps to stabilize the pressure in the system, prevent the separation membrane 20 and other components from being damaged by sudden pressure changes caused by excessive instantaneous flow, and ensure the stable operation of the entire device.

[0075] After being temporarily stored in the buffer chamber 110, the mixed phase has the opportunity to further mix evenly or undergo some pre-separation processes (such as partial gas-liquid separation, etc.) in a relatively stable environment, making the mixed phase state entering the separation chamber 107 more conducive to the separation operation, thereby improving the separation effect and purity of the organic phase and the non-organic phase. For example, for some mixed phases containing tiny bubbles, the residence time in the buffer chamber 110 can allow the bubbles to rise and escape, reducing the interference of the bubbles on the separation process of the separation membrane 20.

[0076] The existence of the buffer chamber 110 provides an adjustable link for the entire extraction and separation process. By controlling the storage time, flow rate and other parameters of the mixed phase in the buffer chamber 110, the process can be flexibly adjusted according to different raw material characteristics and separation requirements.

[0077] In some embodiments, see Figure 2 , Figure 4 and Figure 5 , the separation chamber 107 extends in an S shape.

[0078] The S-shaped extension means that the shape of the separation chamber 107 is extended along a curve track similar to the English letter “S”. This shape design will change the flow path, residence time and contact mode of the mixed phase with the separation membrane 20 in the separation chamber 107.

[0079] For example, guide fins may be provided on the inner surface of the S-shaped separation chamber 107. These fins are distributed along the curve direction of the S shape, and their function is to guide the mixed phase to flow more orderly in the separation chamber 107, avoiding turbulence or excessively fast or slow local flow rates. For example, the fins may be designed in a spiral shape, so that the mixed phase generates a certain rotational motion while flowing along the S-shaped path, thereby increasing the contact opportunity and contact area between the mixed phase and the separation membrane 20, and improving the separation efficiency.

[0080] The S-shaped extended separation chamber 107 greatly increases the flow path length of the mixed phase in the separation chamber 107, and the residence time of the mixed phase in the chamber is significantly prolonged compared to the straight or simple shaped separation chamber 107. This allows the organic phase and the non-organic phase to have more time to interact with the separation membrane 20, thereby improving the thoroughness and accuracy of the separation. For example, for some mixed systems that are difficult to separate and have small differences between the two phases, a longer contact time can enable the separation membrane 20 to more effectively screen and separate different components.

[0081] In addition, when the mixed phase flows in the S-shaped cavity, the flow direction is constantly changed, which will produce internal stirring and mixing effects, avoiding local uneven concentration and keeping the mixed phase in a relatively uniform state throughout the separation process.

[0082] In some embodiments, see Figure 2 , Figure 4 and Figure 5 , the flow channel length of the separation chamber 107 is greater than or equal to 1 cm and less than or equal to 1.5 cm.

[0083] The flow channel length refers to the length of the flow path of the mixed phase in the separation chamber 107. It is the length of the channel through which the liquid flows, starting from the inlet of the mixed phase entering the separation chamber 107 to the outlet of the separation chamber 107.

[0084] The specific flow channel length of the separation chamber 107 is not limited herein, for example, it can be 1 cm, 1.05 cm, 1.1 cm, 1.15 cm, 1.2 cm, 1.25 cm, 1.3 cm, 1.35 cm, 1.4 cm, 1.45 cm, 1.5 cm, etc.

[0085] The flow channel length between 1 cm and 1.5 cm can ensure that the mixed phase has enough time and distance to contact the separation membrane 20. Sufficient contact time allows the separation membrane 20 to fully exert its selective permeation function, effectively separate the organic phase and the non-organic phase, and ensure the efficiency and quality of separation. For example, for some mixed phases containing complex components, a suitable flow channel length can gradually separate the various components according to their permeability differences in the separation membrane 20.

[0086] In some embodiments, see Figure 2 , Figure 4 and Figure 5 The equivalent diameter of the flow cross section of the separation chamber 107 is greater than or equal to 450 nm and less than or equal to 800 nm.

[0087] The flow cross section refers to the cross section perpendicular to the flow direction of the mixed phase in the separation chamber 107. The mixed phase passes through this cross section, and its shape and size will affect the flow rate, pressure distribution and contact with the separation membrane 20 of the mixed phase.

[0088] For non-circular flow cross-sections, in order to facilitate analysis and comparison, equivalent diameter is used to describe its size characteristics. Equivalent diameter refers to the diameter of a circle with the same area as the non-circular cross-section. The equivalent diameter can be used to uniformly measure the effects of flow cross-sections of different shapes in fluid mechanics and separation processes.

[0089] The specific equivalent diameter size of the flow cross section of the separation chamber 107 is not limited here, for example, it can be 450nm, 500nm, 550nm, 600nm, 650nm, 700nm, 750nm, 800nm, etc.

[0090] The appropriate equivalent diameter range of the flow cross section can control the flow rate and pressure of the mixed phase in the separation chamber 107, so that the organic phase and the non-organic phase have suitable dynamic conditions when they contact the separation membrane 20. The flow rate should not be too fast to cause the separation membrane 20 to have no time to separate, nor should it be too slow to affect the processing capacity and separation effect. For example, for the separation of some organic phases and non-organic phases with small molecular size differences, the flow rate and pressure can be accurately adjusted within this equivalent diameter range, so that the separation membrane 20 can give full play to its selective separation function, improve separation efficiency and product purity.

[0091] In some embodiments, see Figure 2 , Figure 4 and Figure 5 , the material of the separation membrane 20 includes polytetrafluoroethylene.

[0092] Polytetrafluoroethylene is a high molecular polymer material with many unique properties. It is polymerized from tetrafluoroethylene monomers. In the chemical structure, fluorine atoms tightly surround carbon atoms to form a highly stable structure. With its excellent chemical stability, low surface energy and good heat resistance, polytetrafluoroethylene can cope with a variety of complex chemical environments and working conditions during the extraction and separation process. The hydrophobic and oleophilic properties of polytetrafluoroethylene can play a key supporting role in achieving the effective separation of organic and non-organic phases.

[0093] For example, a multi-layered polytetrafluoroethylene separation membrane 20 is constructed, and each layer of polytetrafluoroethylene has a different pore size or density. For example, a layer of polytetrafluoroethylene with a large pore size is provided as a support layer to provide mechanical strength, and then a layer of polytetrafluoroethylene with a small pore size is covered on its surface as a separation function layer, which not only ensures the overall strength of the separation membrane 20, but also realizes a fine separation function.

[0094] Here, the thickness of the polytetrafluoroethylene membrane is greater than or equal to 45 μm and less than 50 μm, and the pore size of the polytetrafluoroethylene membrane is greater than or equal to 450 nm and less than or equal to 800 nm.

[0095] Polytetrafluoroethylene has extremely strong chemical inertness and can withstand the erosion of almost all chemical reagents such as strong acids, strong bases, strong oxidants, etc. In the extraction and separation process, whether it is an acidic or alkaline mixed liquid, or a system containing strong oxidizing substances, the polytetrafluoroethylene separation membrane 20 can maintain the stability of its structure and performance, and is not prone to chemical reactions that cause damage to the membrane or performance degradation, thereby ensuring the long-term stable operation of the separation process.

[0096] In some embodiments, see Figure 2 The material of the main body 10 includes polymethyl methacrylate.

[0097] Polymethyl methacrylate is a high molecular polymer material, also known as organic glass. It has good transparency, mechanical properties and chemical stability, and can be made into various shapes through various processing methods such as injection molding and extrusion.

[0098] Polymethyl methacrylate has the characteristic of high transparency, which allows the operator to directly observe the flow of the liquid inside the device, the mixing state and the working state of each component (such as whether the separation membrane 20 is blocked, etc.). This is very helpful for monitoring the extraction and separation process, timely discovering problems and making adjustments, especially in research and experimental environments, where experimental phenomena can be easily observed. At the same time, polymethyl methacrylate can withstand the corrosion of various chemical substances, and to a certain extent can resist the erosion of the main body 10 by organic solvents, acid and alkali solutions, etc. used in the extraction and separation process. This helps to extend the service life of the device, reduce the maintenance and replacement costs caused by material damage, and also ensure the safety and stability of the extraction and separation process, and avoid problems such as liquid leakage caused by material corrosion. Furthermore, polymethyl methacrylate can be made into complex shapes through a variety of processing methods, which can well meet the design requirements of the main body 10 for various channels, chambers and other complex structures. This allows the shape and size of the main body 10 to be flexibly designed according to specific process requirements and spatial layout when manufacturing the extraction and separation device 100, which is conducive to optimizing the performance of the device and improving space utilization.

[0099] In some embodiments, see Figure 2 , the volume of the mixing chamber 106 is greater than or equal to 3 cm 3 , and less than or equal to 3.2cm 3 .

[0100] The specific volume of the mixing chamber 106 is not limited here, and can be, for example, 3 cm 3 、3.01cm 3 、3.02cm 3 、3.03cm 3 、3.04cm 3 、3.05cm 3 、3.06cm 3 、3.07cm 3 、3.08cm 3 、3.09cm 3 、3.1cm 3 、3.11cm 3 、3.12cm 3 、3.13cm 3 、3.14cm 3 、3.15cm 3 、3.16cm 3 、3.17cm 3 、3.18cm 3 、3.19cm 3 、3.2cm 3 etc.

[0101] Exemplarily, the mixing chamber 106 is a cylindrical cavity with a diameter of 12 mm and a depth of 7 mm.

[0102] Setting the mixing chamber 106 within the above range can ensure that there is enough space for the liquid to be fully mixed, but it will not be too large to cause the liquid to stay in the chamber for too long or to be mixed unevenly. At the same time, it is also necessary to consider the size compatibility with the entire device and the balance between processing volume and efficiency. This volume range is compatible with other components of the entire extraction and separation device 100, and the overall structure of the device will not be bloated due to the excessive volume of the mixing chamber 106, nor will the processing volume be limited due to the small volume. It helps to achieve the balance and stability of the liquid flow inside the device, improve the reliability and stability of the device as a whole, extend the service life of the device, and reduce maintenance costs.

[0103] In some embodiments, see Figure 2 The main body 10 includes a first body 111 and a second body 112 arranged along a thickness direction.

[0104] The first body 111 is a portion of the structure divided from the main body 10 along the thickness direction, which undertakes specific functions or accommodates related components, and cooperates with the second body 112 .

[0105] The second body 112 corresponds to the first body 111 and is also a component of the main body 10 in the thickness direction. It works in conjunction with the first body 111, for example, in terms of accommodating chambers, channel connections, and providing installation locations for components such as the separation membrane 20, so as to achieve the extraction and separation function of the entire device.

[0106] The originally integrated main body 10 is split into two parts in the thickness direction, namely the first main body 111 and the second main body 112 , which is beneficial to the molding and manufacturing of the internal structure and convenient for the installation and maintenance of the internal components.

[0107] In some embodiments, see Figure 2 The first body 111 is connected to the second body 112 by thermal compression bonding.

[0108] Thermocompression bonding is a connection process method that uses heating and pressure to soften, flow and diffuse the materials at the connection interface of two parts (here, the first body 111 and the second body 112) to form a strong connection bond. This connection method usually requires that the materials to be connected have a certain degree of thermoplasticity or can interact with each other under heating conditions to achieve a good connection effect.

[0109] Thermocompression bonding can form a tight bond at the connection interface between the first body 111 and the second body 112, effectively preventing leakage of liquid and gas inside the device. During the extraction and separation process, good sealing is very important for maintaining the pressure stability inside the device, ensuring that the liquid flows in the specified channels and chambers, and preventing the separated substances from leaking into the external environment, thereby ensuring the accuracy and safety of the extraction and separation process.

[0110] In some embodiments, the body portion 10 includes a third body 113 , and the third body 113 is connected to the second body 112 by thermocompression bonding.

[0111] The third body 113 is one of the components of the main body 10 and cooperates with the first body 111 and the second body 112. It has a specific structure shape and function, and is used to provide a space for the first body 111 and the second body 112 to be installed and supported.

[0112] The hot pressing bonding connection surface between the third body 113 and the second body 112 can be designed with a special shape structure. For example, a toothed connection surface or a wavy connection surface with concave and convex matching is adopted. Compared with a plane connection, this special shape can increase the contact area of ​​the connection interface during the hot pressing process, promote the mutual diffusion and bonding of material molecules, thereby further improving the strength and stability of the connection, and is also conducive to resisting shear force and tension after connection, and preventing the separation or loosening of the connection surface.

[0113] In some embodiments, see Figure 2 The extraction and separation device 100 includes a polycarbonate membrane 30 , which seals the first liquid storage chamber 108 and / or the second liquid storage chamber 109 .

[0114] Polycarbonate is a high molecular polymer with good mechanical properties, optical properties and chemical stability. The polycarbonate film 30 is a thin film component made of polycarbonate as the main material, which is relatively thin and has certain flexibility and strength.

[0115] The polycarbonate membrane 30 is a component of the extraction and separation device 100, and its main function is to seal the first liquid storage chamber 108 and / or the second liquid storage chamber 109. The polycarbonate membrane 30 is placed in a position that can prevent liquid from flowing out of the liquid storage chamber or foreign matter from entering the liquid storage chamber, and it may achieve the sealing function by being attached to the opening edge of the liquid storage chamber or serving as a partition layer of the liquid storage chamber.

[0116] The sealing form of the polycarbonate film 30 is not limited here. For example, the first liquid storage chamber 108 and / or the second liquid storage chamber 109 may be sealed by heat pressing bonding.

[0117] Polycarbonate itself has excellent chemical stability and can withstand corrosion from a variety of chemical substances. In the liquid storage chamber, whether storing acidic, alkaline or organic solvent liquids, the polycarbonate membrane 30 can effectively prevent the liquid from corroding the sealing material, thereby ensuring the long-term effectiveness of the seal and reducing the risk of liquid leakage due to damage to the sealing material. The polycarbonate membrane 30 has high strength and toughness and can withstand certain pressure and tensile forces. When the internal pressure of the liquid storage chamber changes or is subjected to external impact, it can maintain the integrity of the structure and will not easily break or deform, ensuring the reliability of the seal, helping to maintain the stability of the internal environment of the liquid storage chamber, and ensuring the smooth progress of the extraction and separation process. The polycarbonate material has a certain degree of transparency. If it is necessary to observe the liquid level, color, etc. of the liquid in the liquid storage chamber, it is conducive to the detection of the solution components in the first liquid storage chamber 108 and / or the second liquid storage chamber 109.

[0118] For example, the thickness of the polycarbonate film 30 is greater than or equal to 0.05 mm and less than or equal to 0.15 nm. The polycarbonate material itself has no X-ray fluorescence signal, and the sealing liquid does not interfere with the measurement of actinide elements such as uranium, neptunium and plutonium. The 0.1 mm polycarbonate film has good flexibility and a suitable softening temperature, which is conducive to bonding it to the chip substrate using a hot press bonding process.

[0119] This embodiment of the application provides an extraction separation system 1000, please refer to Figure 1 The extraction and separation system 1000 includes an X-ray tube 200, a detector 300, a driving assembly 400, and the extraction and separation device 100 in any embodiment of the present application. The driving assembly 400 is used to drive the first liquid storage chamber 108 or the second liquid storage chamber 109 of the extraction and separation device 100 to approach or move away from the X-ray tube 200, the X-ray tube 200 irradiates the phase to be detected in the first liquid storage chamber 108 or the second liquid storage chamber 109, and the detector 300 detects the components of the phase to be detected.

[0120] The extraction and separation system 1000 is a comprehensive device system that integrates a variety of components and equipment. Its core function is to first use the extraction and separation device 100 to separate the mixture, and then use the X-ray tube 200, detector 300, etc. to detect and analyze the separated substances to obtain detailed information about the substances.

[0121] The X-ray tube 200 is a device capable of generating X-rays. It accelerates electrons and makes them collide with a specific target material, so that the inner electrons of the target material atoms transition to generate X-ray radiation. In the extraction and separation system 1000, it is used as an excitation source to irradiate the phase to be detected in the liquid storage chamber of the extraction and separation device 100, so that the atoms in the phase to be detected interact with each other and generate characteristic information related to the composition of the substance.

[0122] Exemplarily, a protective shielding device, such as a lead shielding cover, is provided around the X-ray tube 200 and the detector 300. Since X-rays are radioactive, the protective shielding device can effectively block the leakage of X-rays to the surrounding environment and protect the operator from radiation hazards. At the same time, the shielding device can also reduce the interference of stray scattered rays in the external environment on the detection results, improve the signal-to-noise ratio of the detection signal of the detector 300, and thus improve the accuracy of the detection.

[0123] The detector 300 is a device for detecting various signals generated by the interaction between X-rays and the phase to be detected. These signals may include scattering, absorption, fluorescence emission, etc. of X-rays. The detector 300 can convert these signals into measurable and analyzable data, and then determine the composition of the phase to be detected, such as the type and content of elements.

[0124] The driving assembly 400 is a mechanical device, which functions to provide power and control the position movement of the first liquid storage chamber 108 or the second liquid storage chamber 109 of the extraction and separation device 100 relative to the X-ray tube 200. It can realize the operation of the liquid storage chamber approaching or moving away from the X-ray tube 200, so that the liquid storage chamber is accurately positioned at a suitable detection position when detection is required, and can be moved away when detection is not required without affecting other operations. The driving assembly 400 can also be remotely operated to reduce the number of operators remaining in the radiation environment and protect personnel safety.

[0125] Exemplarily, a positioning and locking mechanism is added to the connection between the drive assembly 400 and the first liquid storage chamber 108 or the second liquid storage chamber 109. When the drive assembly 400 moves the liquid storage chamber to the detection position of the X-ray tube 200, the mechanism can accurately locate the position of the liquid storage chamber, ensuring that the liquid storage chamber is in the same and accurate irradiation area during each detection, thereby improving the repeatability and accuracy of the detection results. In addition, the liquid storage chamber can be locked during the detection process to prevent the position of the liquid storage chamber from being offset due to external factors (such as vibration, etc.) and affecting the detection results.

[0126] First, the extraction and separation device 100 separates the mixture into different phases and stores them in the first liquid storage chamber 108 and the second liquid storage chamber 109. Then, when it is necessary to detect the liquid in one of the liquid storage chambers, the driving component 400 takes effect and moves the corresponding liquid storage chamber to the irradiation area of ​​the X-ray tube 200. The X-ray tube 200 emits X-rays to irradiate the liquid in the liquid storage chamber. The atoms in the liquid interact with the X-rays to generate various signals. These signals are captured by the detector 300 and converted into data. Finally, the composition of the liquid is determined by analyzing the data.

[0127] The extraction and separation system 1000 integrates the extraction and separation function with the detection function, realizing a one-stop operation from mixture separation to component detection. It reduces the loss and error in the sample transfer process and improves the efficiency of the entire analysis process. For example, in a chemical analysis laboratory, for the study of complex mixtures, separation and detection can be completed directly in this system without transferring the separated samples to other detection equipment, saving time and labor costs, improving detection efficiency, and also reducing the risk of sample contamination or loss.

[0128] The above description is only a preferred embodiment of the present application and is not intended to limit the present application. For those skilled in the art, the present application can have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application are included in the protection scope of the present application.

Claims

1. An extraction separation device, characterized in that: The extraction and separation device comprises a main body and a separation membrane, wherein the main body comprises: A liquid inlet, the liquid inlet being arranged on the outer surface of the main body; a first channel and a mixing chamber, wherein the liquid inlet is connected to the mixing chamber through the first channel; a second channel and a separation chamber, wherein the separation membrane is disposed in the separation chamber and divides the separation chamber into a first sub-chamber and a second sub-chamber, the first sub-chamber is connected to the mixing chamber through the second channel, and the separation membrane is used to prevent the non-organic phase in the first sub-chamber from entering the second sub-chamber; a third channel and a first liquid storage chamber, wherein the first liquid storage chamber is connected with the second sub-chamber through the third channel; A fourth channel and a second liquid storage chamber, wherein the second liquid storage chamber is connected with the first sub-chamber through the fourth channel.

2. The extraction separation device according to claim 1, characterized in that: The first liquid storage chamber and the second liquid storage chamber are arranged on both sides of the main body along the length direction, and the mixing chamber and the separation chamber are arranged between the first liquid storage chamber and the second liquid storage chamber.

3. The extraction separation device according to any one of claims 1 to 2, characterized in that: The main body comprises an air outlet, the air outlet is arranged on the outer surface of the main body, and the air outlet is communicated with the mixing chamber; and / or, A buffer chamber is defined inside the main body, the second channel penetrates the buffer chamber, and the mixed phase flowing out of the mixing chamber is stored in the buffer chamber.

4. The extraction separation device according to any one of claims 1 to 2, characterized in that: The separation chamber extends in an S shape.

5. The extraction separation device according to claim 4, characterized in that: The flow channel length of the separation chamber is greater than or equal to 1 cm and less than or equal to 1.5 cm; and / or, The equivalent diameter of the flow cross section of the separation chamber is greater than or equal to 450 nm and less than or equal to 800 nm.

6. The extraction separation device according to any one of claims 1 to 2, characterized in that: The material of the separation membrane includes polytetrafluoroethylene; and / or, The material of the main body includes polymethyl methacrylate; and / or, The volume of the mixing chamber is greater than or equal to 3 cm 3 , and less than or equal to 3.2cm 3 .

7. The extraction separation device according to any one of claims 1 to 2, characterized in that: The body portion includes a first body and a second body arranged along a thickness direction.

8. The extraction separation device according to claim 7, characterized in that: The first body is connected to the second body by thermocompression bonding; and / or, The main body portion includes a third body, and the third body is connected to the second body by thermocompression bonding.

9. The extraction separation device according to any one of claims 1 to 2, characterized in that: The extraction and separation device comprises a polycarbonate membrane, and the polycarbonate membrane seals the first liquid storage chamber and / or the second liquid storage chamber.

10. An extraction separation system, characterized in that: The extraction and separation system comprises an X-ray tube, a detector, a drive assembly and the extraction and separation device according to any one of claims 1 to 9; The driving assembly is used to drive the first liquid storage chamber or the second liquid storage chamber of the extraction and separation device to be close to or away from the X-ray tube, the X-ray tube irradiates the phase to be detected in the first liquid storage chamber or the second liquid storage chamber, and the detector detects the components of the phase to be detected.

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